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1 ical for proper force transmission and force bearing.
2 ill aid those new to the field to find their bearings.
4 e and an annulated fifth (or isocyclic) ring bearing 13(1)-oxo and 13(2)-carbomethoxy substituents.
5 tion of DTMGM-SEGPHOS, a bisphosphine ligand bearing 3,5-bis(trimethylgermanyl)-4-methoxyphenyl group
6 ining effective cyclization of such peptides bearing 3,5-dihydroxyphenylglycine residues at position
8 this approach can convert any aromatic ring bearing a -CH(2) Br or a -CHO group into a pyrene moiety
12 ted ring-opening product, dibenzosuberenone, bearing a beta-amino-alpha-ketone group was secured by X
13 ), cyclo-C(6)H(11), t-Bu, cyclopropylmethyl) bearing a bulky bidentate 2-[bis(adamant-1-yl)phosphino]
14 construction of a library of isoindolinones bearing a congested carbon in good to excellent yields u
17 re we characterize a likely effector protein bearing a deubiquitylase (DUB) domain from the obligate
18 A represents a basic form of the sub-family bearing a dioxopiperazine core and a rare 3-spiro-psi-in
19 expression in mPFC and BLA, by crossing mice bearing a floxed Rapgef2 allele with a cre mouse line dr
21 at an H9N2 avian influenza reassortant virus bearing a human-origin H1N1/2009 PA gene was attenuated
22 s of alpha-phenyl-N-tert-butyl nitrone (PBN) bearing a hydroxyl, an acetate, or an acetamide substitu
23 n of trisubstitued cyclopentane carboxylates bearing a leaving group (at the C-4 position) and an add
24 nthesis of a new NDBF-based protecting group bearing a methoxy substituent and use it to prepare a pr
25 esults in the formation of pyrrolidine rings bearing a new stereogenic center on the C2 of the five-m
27 we reveal a 14- angstrom structure of LRRK2 bearing a pathogenic mutation that oligomerizes as a rig
28 The unreactivity of the alkyne terminus not bearing a phenyl ring is because the cyclization is ther
29 of key 4-propargylisoxazole building blocks bearing a pyrid-2-yl or quinolin-2-yl substituent at the
30 RINC5 reduced the binding of HIV-1 particles bearing a SERINC5-susceptible Env to antibodies that rec
31 e m6A target and a biotinylated RNA oligomer bearing a single m6A enzymatically labelled with a comme
32 eomeric 2-(2-pyrrolidinyl)-1,4-benzodioxanes bearing a small, hydrogen-bonding substituent at the 7-,
33 r protein, has been reported to recruit RNAs bearing a specific sequence (EXO motif) into exosomes.
35 new class of organo-iridium drug candidates bearing a structural feature that results in a leap in a
37 razole-based derivatives, NDM-1 by compounds bearing a thiol, a thiosemicarbazide or thiosemicarbazon
38 p optimization revealed that (68)Ga-HTK03041 bearing a tranexamic acid-9-anthrylalanine affinity-modi
39 original enantiopure aza-tricyclic scaffolds bearing a trifluoromethyl substituent at the bridgehead
40 ted by the synthesis of 35 different ketones bearing a wide variety of functional groups with an aver
41 the preparation of ten new hangman chlorins bearing a xanthene backbone and a pendant carboxylic aci
42 port crystal structures of substrate mimetic bearing ACPs in complex with the elongating KSs from Esc
43 tic barrier, we developed polymeric micelles bearing active formats of irinotecan and oxaliplatin, SN
45 ng domain fused to IL-12 (CBD-IL-12) in mice bearing aggressive mouse tumours, CBD-IL-12 accumulates
48 ing to produce a variety of dibenzosuberones bearing an isoxazole group in 24 to >99% (1)H NMR yields
49 rofiles for rat P2X2 receptors; triphosphate-bearing analogues display broad activity, tolerating a n
50 , we assessed the presence of Ag-bearing, Ti-bearing, and Ce-bearing NPs in the Barcelona catchment a
53 an survival as a monotherapy in KR158 glioma-bearing animals and further increased median and overall
54 s studies, treatment of autochthonous tumour-bearing animals with Telaglenastat (CB-839), an orally b
55 ive study analyzed hip joints seen on weight-bearing anterior-posterior pelvic radiographs from parti
56 o ligation between a trans-cyclooctene (TCO)-bearing antibody and a tetrazine (Tz)-based radioligand
58 -L1 treatment restricts tumor growth in mice bearing ARID2-knockout melanoma cells, correlating with
60 mic control of tumor vessels in C57BL/6 mice bearing B16 melanoma was performed using volume expansio
61 ongested coupling partners, as well as those bearing base- and nucleophile-sensitive functional group
65 ies and excellent osteoconductivity for load-bearing bone defects repair is still challenging in the
66 rhabdomeric-opsin in eye photoreceptor cells bearing both microvilli and cilia in larva of the anneli
67 tically pure transition metal (TM) complexes bearing C(1)- and C(2)-symmetric N-heterocyclic carbene
73 actory epithelium in adult mice, and rosette-bearing cells often have free centrioles in addition.
74 ght to form a gel-like matrix between stress-bearing cellulose microfibrils in growing plant cell wal
75 ropanecarboxylic acids and cyclopropylamines bearing CH(2)F, CHF(2), and CF(3) substituents were synt
76 ction in most animals is mediated by neurons bearing cilia that are accessible to the environment.
77 st-implantation development of human embryos bearing common aneuploidies using a recently established
78 is strategy via coupling of two prerotaxanes bearing complementary linker functionalities (i.e., azid
79 in order to link DNA origami nanostructures bearing complementary strands into micrometer-long one-d
80 o mid-ocean ridge basalts and contain two Cl-bearing components with elevated isotopic compositions r
82 esicle trafficking and cell wall deposition, bearing consequences in pollen-stigma interactions and P
83 wearable tourniquet, a transforming and load-bearing deployable structure, and an untethered, self-st
84 ield of deuterium labelling, where compounds bearing deuterium ((2)H) atoms at chiral centres are bec
86 ression in neurons, studies of animal models bearing different disease-causing mutations, and more in
87 hols and a wide variety of arylacetonitriles bearing different functional groups were converted into
89 Here, we assessed aberrant expression of AR bearing different polyQ tracts and stabilized beta-caten
90 demonstrated in the synthesis of acylsilanes bearing different silyl groups as well as in situ reduct
91 of these CB[8]-secured Pt(II) complex dimers bearing different tpy "heads" and thiolate "tails" scram
94 million-year-old supernovae with the (60)Fe-bearing dust particles still permeating the interstellar
95 of the bacteriophage Enterococcus hirae Mice bearing E. hirae harboring this prophage mounted a TMP-s
97 onstrated that the coordination of catechols bearing EDGs led to deep-red positively charged complexe
98 ol-5-yl)pyridine luminophoric pincer ligands bearing either CF(3) or (t)Bu moieties on the triazole r
100 ggest that unsymmetrical aniline derivatives bearing electron withdrawing groups are preferred compar
104 We created a series of hybrid PKS modules bearing exchanged TE domains from heterologous pathways
105 A and CpG DNA induce the secretion of ADAM10-bearing exosomes from human cells as well as in mice.
109 perience significant infiltration by a water-bearing fluid may release orders of magnitude more CO(2)
113 type, the NOS-1 AC: a multistratified, axon-bearing GABAergic cell, with dendrites in both ON and OF
114 method utilizes accessible carbamate esters bearing gamma-propargylic C-H bonds and furnishes versat
116 ome, which is formed by the repair of lesion-bearing HBV relaxed circular DNA delivered by the virion
122 ally, we provide evidence that primary FCRL4-bearing human memory B cells are constitutively bound to
123 ells by positron emission tomography in mice bearing human papillomavirus-positive tumors, as well as
124 ment with CEA-TCB/CEA-4-1BBL in MKN-45 tumor-bearing humanized mice correlated with intratumoral CD8(
125 In ovalbumin (OVA)-expressing E.G-7 tumor-bearing immune-deficient mice, intravenously injected Cy
127 nicians may consider the use of early weight-bearing in a functional brace as a safe and cost-effecti
128 was not found to be superior to early weight-bearing in a functional brace, as measured by ATRS, in t
129 n polycarpic plants, we focused on alternate bearing in Citrus trees that had been experimentally est
132 Molecular dynamics simulations of such ions bearing intrinsically charged labels reveal evidence of
136 with conventional memory T cell populations, bearing little resemblance to recently activated effecto
141 features with clonal inflammatory disorders bearing MEK and RUNX1 mutations such as histiocytoses an
142 cted oceanic lithosphere destabilizes carbon-bearing metals to form diamond, without disturbing the a
143 methyl, and methoxy, as well as 2-pyridone-N-bearing methyl, cyclopropyl methyl, cyclopentyl methyl,
144 determined by longitudinal imaging of tumor-bearing mice (MC38 and A9F1) undergoing 2 types of chemo
149 6 was abundantly expressed in MDSCs in tumor-bearing mice and patients with human colorectal cancer.
150 reverses excessive lipid oxidation in tumor-bearing mice and prevents cancer cachexia, even under ca
151 ssion and long-term survival in 87.5% of GBM-bearing mice and prime the immune system to develop anti
152 l mNK cells in spleens of MYC(ON) T-lymphoma-bearing mice exhibit perturbations in the terminal NK ef
157 l/proliferation, and survival in brain tumor-bearing mice treated with PT2385 alone and in combinatio
160 of this preclinical model, a cohort of tumor-bearing mice were injected with the chemotherapeutic dru
162 Treatment of orthotopic pancreatic tumor-bearing mice with gemcitabine alone or in combination wi
178 w that a single removable transdermal patch, bearing microneedles loaded with insulin and a non-degra
179 was first interpreted as fossilized vacuole-bearing microorganisms, but later regarded as artifactua
180 ting to mediastinal draining lymph nodes and bearing migratory and immunoregulatory markers, includin
182 near folding motions of such sheets to force-bearing modes in conjunction with the Maxwell-Calladine
187 zation process to access chiral cyclopentane bearing multiple stereocenters with excellent enantiosel
188 the reaction were explored, with piperidines bearing multiple substitution patterns providing the ary
190 des, a significant increase of phospholipids bearing n-3 fatty acids (most in PC and PE) was also rec
191 oming peptides, immunostimulatory nucleotide-bearing nanoparticles facilitate antitumor efficacy afte
194 h COVID-19 platelet-rich plasma generated TF-bearing NETs that induced thrombotic activity of HAECs.
195 first preparation of 3-aryloxazolidin-2-ones bearing new functionalized C-5 substituents derived from
196 ls and Methods A total of 21 VX2 liver tumor-bearing New Zealand white rabbits were used between Octo
197 polymers synthesized by RAFT polymerization, bearing no specific functional end group, by means of he
198 ell-type-specific incorporation of the azide-bearing non-canonical-amino-acid azidonorleucine (ANL) d
199 ith native substrates and hybrid PKS modules bearing non-cognate TE domains was severely reduced.
200 e presence of Ag-bearing, Ti-bearing, and Ce-bearing NPs in the Barcelona catchment area, including t
203 ng and care planning, as well as a potential bearing on cost effectiveness within early pregnancy car
206 fection process in the host have significant bearings on both recovery from the disease and on the co
209 Hills 84001, preserve indigenous nitrogen(N)-bearing organics by developing a new technique for high-
212 -economic synthesis of aryliminophosphoranes bearing ortho urea was achieved via unprecedented Ph(3)P
214 n vivo studies using a syngeneic mouse model bearing orthotopically injected 4T1 cells, Cl-OCH3 decre
215 Systemic induction of senescence in nontumor-bearing p16-3MR mice using a chemotherapy followed by th
216 cleus with nuclear localization signal (NLS)-bearing paralogues in the NMCP1-clade was discounted bas
218 -labeled ligands in human prostate carcinoma bearing (PC-3) mice revealed two compounds with a biodis
225 es of protein mechanics, to serving as force-bearing protein linker for modulation of mechanotransduc
227 peroxisomes in the anaerobic, hydrogenosome-bearing protist Mastigamoeba balamuthi We found a conser
228 (203)Pb-L1-(203)Pb-L5 were performed on mice bearing PSMA(+) PC3 PIP and PSMA(-) PC3 flu flank xenogr
231 Zweifel olefinations provide trifluoromethyl-bearing quaternary stereocenters substituted with alkene
234 em, we designed seven variants of GB1 domain bearing R1 spin label and recorded the corresponding MD
235 lycine SNR was significantly higher in tumor-bearing rats compared to controls, and in tumor regions
236 ctate in the brains of unaffected and glioma-bearing rats following the administration of (2)H(2)-lab
237 but synthesis of polysubstituted thiophenes bearing reactive groups is difficult because of high rea
238 beled multi-triazolo-peptidomimetics in mice bearing receptor-positive tumor xenografts revealed up t
239 c crust, not sediment, is the primary carbon-bearing reservoir in slabs subducted to deep-lithospheri
240 er-deep borehole (SG-3, 12,262 m depth) gold-bearing rocks of Archaean age have been located at depth
241 nd control groups (n = 6-7) using C4-2 tumor-bearing SCID mice by evaluating tumor growth and surviva
242 d to simulate multiphase flow in gas hydrate-bearing sediments where the proposed relative permeabili
244 g from a platform Rhodobacter sphaeroides RC bearing several amino acid changes, an Arg in place of t
245 77)Lu-PSMA I&T was determined in LNCaP tumor-bearing severe combined immunodeficiency (SCID) mice aft
246 er membrane vesicle-like features, while NPs bearing short cationic ligands only exhibit weak membran
247 -regulated downstream genes in tumor samples bearing short polyQ AR versus those with longer polyQ tr
248 essive tumor phenotypes in the compound mice bearing short polyQ tract AR and stabilized beta-catenin
252 odified magnesium alloy as the internal load-bearing skeleton and bioglass-magnesium phosphate bone c
257 diffraction indicated that U-As-Ca- and U-Ca-bearing solids resemble uranospinite [Ca(UO(2))(2)(AsO(4
261 ir-regenerating capability, and produce skin bearing striking resemblance to irreversible human alope
262 ndium catalyst hydrodefluorinates substrates bearing strong aryl C-F bonds, including difluoro- and f
264 -DOTATATE by PET/CT imaging in NOD-SCID mice bearing subcutaneous somatostatin receptor-expressing AR
265 imaging was performed on female BALB/C mice bearing syngeneic 4T07 (nonmetastatic) and 4T1 (metastat
268 We found that the BET N-terminal halves bearing the bromodomains convey marked differences in pr
269 at cristae junctions in patient fibroblasts bearing the CHCHD10(S59L) mutation, the role of CHCHD10
270 Lewy body dementia; in particular, patients bearing the E46K disease mutation manifest a clinical pi
271 roduces a putative truncated AtPRMT3 protein bearing the entire N-terminus but lacking an intact enzy
273 in a duplicated preprotein pair, the isoform bearing the leucoplast motif usually has greater root pr
275 ps28 protein, translated in cis from an mRNA bearing the RPS28B 3'UTR, physically interacts more stro
278 /refractory patients, including plasma cells bearing the t(4;14) translocation obtained from patients
279 in all variants, full-length AfGcHK variants bearing the Y15A or Y15G substitutions lack enzymatic ac
280 rticular, in the past decade, many compounds bearing these heterocycles have been studied for their p
281 diazoacetates to afford stable norcaradienes bearing three stereogenic centers, one of which is an al
282 resent study, we assessed the presence of Ag-bearing, Ti-bearing, and Ce-bearing NPs in the Barcelona
285 The catalyst contains a phosphine ligand bearing trimethylsilyl-substituted aryl groups and a tri
287 ketone formed a new Zn(4) L(4) tetrahedron 1 bearing twelve uncoordinated pyridyl units around its me
288 l expressing human amyloid precursor protein bearing two familial mutations and asked whether activat
289 mplex L->C(2) using a bulky phosphine ligand bearing two imidazolidin-2-iminato groups (L is (NHC(R)=
291 based lanthanide chelators, L(4b) and L(4c), bearing two specific picolinate two-photon antennas (tai
293 o dynamic PET studies were performed on mice bearing U87 (CXCR4 low-expressing) and U87.CXCR4 (human-
295 ticular, functionalized homopropargyl amines bearing up to three contiguous stereocenters can be prep
296 gments derived from the 5' region of SLC26A9-bearing variants from the low-risk haplotype generated 1