ライフサイエンスコーパス: beauty

1 tand a simple cell in all its complexity and beauty.

2 silk protein fibers that embody strength and beauty.

3 scientists have pursued the goal of defining beauty.

4 sexual selection with its emphasis on sexual beauty.

5 dly complex relationship between fluency and beauty.

6 ed interest in its mechanical properties and beauty.

7 itude increases linearly with the feeling of beauty.

8 and then judged whether they had experienced beauty.

9 e perceive and make inferences about others' beauty.

10 itive inferences when judging others' facial beauty.

11 evolutionary advantages and often with great beauty.

12 r aesthetic preferences for elaborateness or beauty [1-3].

13 on with concepts of aesthetic judgement and 'beauty.'(1)(,)(5-9) We report that during their song and

14 her positively or negatively correlated with beauty across the multiple layers of the DCNN.

15 in average ratings of arousal, valence, and beauty alike.

16 Just like a sleeping beauty, alpha-oxocarboxylic acids were awakened from a 1

17 ment Dadaism challenged established norms of beauty and authority in art.

18 total synthesis of molecules of unimaginable beauty and diversity such as the four discussed in this

19 obtained abstract attribute measures such as beauty and emotional valence for these pieces.

20 ever, I question his ensuing arguments about beauty and goodness, and thereby the practical value of

21 and Western participants to rate stimuli on beauty and liking.

22 bert Burns Woodward's publications exhibit a beauty and majesty infrequently seen in the scientific l

23 on in the brain by studying the link between beauty and neuronal sparsity, a measure of information p

24 ermline transposition frequency for Sleeping Beauty and piggyBac was approximately 10% or about one n

25 ompare them with the preferences of Sleeping Beauty and piggyBac, showing that each superfamily has a

26 The distraction greatly reduces the beauty and pleasure experienced from stimuli that otherw

27 ies in providing ecosystem services, natural beauty and pleasure, and sustaining human lives is a mes

28 Physiogenic and pathogenic oscillations: the beauty and the beast, based on presentations at the annu

29 e results provide a visceral reminder of the beauty and the complexity of living systems.

30 A pearl's distinguished beauty and toughness are attributable to the periodic st

31 analysis of 23,417 piggyBac, 30,303 Sleeping Beauty, and 27,985 TcBuster integrations in HEK-293 cell

32 Truth may be beauty, and beauty truth, in more than a metaphorical se

33 wo transposon systems, PiggyBac and Sleeping Beauty, and give guidance on the use of different engine

34 al role in visual art, it is often linked to beauty, and observers can detect it efficiently in the l

35 d by their geometrical perfection, intrinsic beauty, and particular properties of polyhedranes, a ser

36 e attention due to their symmetry, aesthetic beauty, and potential applications in catalysis, plasmon

37 s challenges that arise, relating to art and beauty, and provide ideas for a way forward.

38 tion by trace element analysis in edible and beauty argan oil is a method that can be generalised.

39 ere assessed by ICP-AES in virgin edible and beauty argan oil samples prepared from four remote locat

40 s and artists alike have since proposed that beauty arises from the interaction between the object an

41 ons of human ICC, we electroporated Sleeping Beauty-based oncogenic transposon plasmids into the left

42 BEAUTY (BLAST Enhanced Alignment Utility) is an enhanced

43 he unique topological complexity and elegant beauty, Borromean systems are attracting intense attenti

44 content of that information, when predicting beauty, but also suggests an unexpectedly complex relati

45 ransposon biology and indicate that Sleeping Beauty can be readily improved for enhanced genetic rese

46 xposure during a hair removal procedure at a beauty center.

47 clinical neurology and, even more often, in beauty clinics.

48 aking the advantage of the attractiveness of beauty colored coverage, and the simple, and non-tousled

49 , practitioners will encounter more and more beauty-conscious teenagers using these products for prev

50 s, and when it does, there is no place for a beauty contest.

51 ue that such sites potentially devolve into "beauty contests" where patients in need are evaluated on

52 c toxicity at smelters, mercury in paint and beauty creams, dioxin in waste oil in Missouri, polychlo

53 vo adeno-associated virus (AAV)-SB (Sleeping Beauty)-CRISPR (clustered regularly interspaced short pa

54 Neuroanatomically, when contemplating beauty, curvilinear contour activated the anterior cingu

55 on sense and philosophy suggest that feeling beauty differs from sensuous pleasures such as eating or

56 ained by non-viral gene transfer of Sleeping Beauty DNA plasmids and selectively expanded ex vivo usi

57 n delivered into the genome via the Sleeping Beauty DNA transposon, suggesting that the observed meth

58 colorectal cancer (CRC) in several Sleeping Beauty DNA transposon-based forward genetic screens in m

59 cer susceptibility gene in multiple Sleeping Beauty DNA transposon-based forward genetic screens in m

60 ied derivatives of the piggyBac and Sleeping Beauty DNA transposons.

61 Transposition of Sleeping Beauty elements has been observed in cultured cells, hep

62 one of the most amazing displays of mineral beauty ever created in nature.

63 s initially focused on objective criteria of beauty ('feature-based aesthetics'), philosophers and ar

64 edict human ratings of arousal, valence, and beauty for images from multiple categories (objects, fac

65 notion that females were attracted to sexual beauty for its own sake.

66 sticated animal, is characterized by natural beauty, graceful movement, athletic endurance, and, as a

67 PiggyBac and Sleeping Beauty have different integration preferences.

68 choices as contributing factors to perceived beauty, health, and age.

69 ru), Striped Parrotfish (Scarus iseri), Rock Beauty (Holacanthus tricolor), Ocean Surgeonfish (Acanth

70 nced with the outdoors, and engaged with the beauty in nature benefited particularly strongly from vi

71 sted a functional transposon called Sleeping Beauty in the one-cell mouse embryo.

72 investigators who seek reinvigoration in the beauty in their craft.

73 accelerates tumorigenesis following Sleeping Beauty insertional mutagenesis in a mouse model of melan

74 from a forward genetic screen using Sleeping Beauty insertional mutagenesis in a mouse model of pancr

75 Sleeping Beauty insertional mutagenesis in this model led to acce

76 Sleeping Beauty is a new tool for unbiased, forward genetic scree

77 The experience of beauty is a pleasure, but common sense and philosophy su

78 Sleeping Beauty is a synthetic "cut-and-paste" transposon of the

79 Sleeping Beauty is an active DNA-transposon system from vertebrat

80 s this idea of interaction by proposing that beauty is determined by the efficiency of information pr

81 That is, to some significant degree, beauty is in the "eye of the beholder." Here, we investi

82 The findings suggest that beauty judgements of art are not strongly calibrated to

83 In the same way that beauty lies in the eye of the beholder, what a stimulus

84 through hydrodynamic injection and sleeping beauty-mediated somatic integration.

85 namic injection in combination with Sleeping Beauty-mediated somatic integration.

86 for malignant progression, we used Sleeping Beauty-mediated transposon mutagenesis, which dramatical

87 A forward genetic screen utilizing Sleeping Beauty mutagenesis in mice previously identified potenti

88 The beauty of conserving germplasm is the securement of gene

89 The beauty of our approach lies in its simplicity: manipulat

90 xhibitions and installations that convey the beauty of plants and the value of herbaria in addressing

91 Beyond the spectacular beauty of such minute structures lie surfaces evolutiona

92 An understanding of the complexities and beauty of the biological process of hearing itself is un

93 Moreover, the beauty of the cascade process is further underscored by

94 The beauty of the eukaryotic cilium has been appreciated sin

95 cular biology while experiencing the natural beauty of the Pacific Coast.

96 over a week and eventually soil and mar the beauty of the temple's iconic tower gates (Gopurams).

97 spin liquids, and to paint a picture of the beauty of the underlying chemistry of this exciting clas

98 able position of being able to share the raw beauty of the world around us-and in the case of neurosc

99 hetic value to environmental conditions, the beauty of the world's reefs appears severely threatened.

100 mmunicate the intricacies, interactions, and beauty of these virus structures.

101 The beauty of this idea lies in its simplicity and testabili

102 e point during his or her education, and the beauty of this process has led many of us to go deeper a

103 ascade of triple C-H bond activations is the beauty of this protocol.

104 The beauty of this transformation is that the easily oxidiza

105 The beauty of zeolite-confined noble metals lies in their un

106 n: either consensus judgments about physical beauty (paracingulate cortex) or individualized preferen

107 ling goal of providing a judgment of liking, beauty, perfection, or similar.

108 preserved TSCM potential using the Sleeping Beauty platform.

109 BEAUTY Post-Processing of submitted search results is av

110 5-7) including representing the diversity of beauty preferences within and across cultures.(8-12) Her

111 his favoritism is not sufficient to create a beauty premium in competitive settings.

112 An account of the "beauty premium" based only on mating motivations overloo

113 There is believed to be a 'beauty premium' in key life outcomes: it is thought that

114 te-based and stereotype explanations for the beauty premium, have too many confounding effects, and l

115 dable, but mating motives do not explain the beauty premium.

116 ate the experimental and field evidence of a beauty premium.

117 dividual by highlighting the type of hygiene/beauty products the person uses, diet, medical status, a

118 Three recent improvements to the BEAUTY program described here make the enhanced output (

119 Theories of universal beauty propose that attractive faces comprise features t

120 ols, including BLAST, FASTA, Smith-Waterman, BEAUTY, PROSITE, and BLOCKS searches.

121 ample of such a transition is the decay of a beauty quark into a strange quark.

122 LSR) indicated that 6-15% of the variance in beauty ratings of the art can be accounted for by the ar

123 ere, we investigated the extent to which the beauty ratings of Western oil paintings from the JenAest

124 ferent types of visual stimuli covaried with beauty ratings.

125 -accounted for nearly 60% of the variance in beauty ratings.

126 load in the presence of the Flp and Sleeping Beauty recombinases.

127 ents of built environment quality (perceived beauty, relaxation potential, nature quality, safe for w

128 sulting nationwide estimates of street-level beauty, relaxation, nature quality, and safety for walki

129 at only the pleasure associated with feeling beauty requires thought and disprove his claim that sens

130 manuel Kant [1, 2] claimed that experiencing beauty requires thought but that sensuous pleasure can b

131 ns included hairdressing or hairdressing and beauty salons.

132 ely used transposons piggyBac (PB), Sleeping Beauty (SB) and Tol2.

133 encing and bioinformatics pipeline, Sleeping Beauty (SB) capture hybridization sequencing (SBCapSeq),

134 In particular, the Sleeping Beauty (SB) DNA transposon has advanced into clinical tr

135 es the DNA damage introduced during Sleeping Beauty (SB) element excision and reinsertion in mammalia

136 he chromosomal transposition of the Sleeping Beauty (SB) element in mouse embryonic stem cells, provi

137 mariner family transposable element Sleeping Beauty (SB) for transgenesis and long-term expression st

138 enesis strategy based on a two-step Sleeping Beauty (SB) forward genetic screen to identify and valid

139 conducted a mutagenic screen using Sleeping Beauty (SB) in mice to identify new candidate cancer gen

140 A Sleeping Beauty (SB) in science refers to a paper whose importanc

141 Sleeping Beauty (SB) is the most active Tc1/mariner-type transpos

142 ively suppresses tumorigenesis in a Sleeping Beauty (SB) mouse model of cancer.

143 vanced DNA vectors derived from the Sleeping Beauty (SB) system to avoid the expense and manufacturin

144 rmits conditional mobilization of a Sleeping Beauty (SB) transposase allele by Cre recombinase to ind

145 ene-delivery system consisting of a Sleeping Beauty (SB) transposase encoded into a messenger RNA del

146 The N-terminal domain of the Sleeping Beauty (SB) transposase mediates transposon DNA binding,

147 The Sleeping Beauty (SB) transposon (Tn) system is a nonviral gene de

148 a novel nonviral vector system, the Sleeping Beauty (SB) transposon (Tn) to insert a wild-type beta-g

149 CD19 CAR T cells generated with the Sleeping Beauty (SB) transposon and differentiated into cytokine-

150 genetic screening system where the Sleeping Beauty (SB) transposon and single guide RNA cassette are

151 ased genome-wide integration of the Sleeping Beauty (SB) transposon by combining it with components o

152 Sleeping Beauty (SB) transposon is a natural nonviral gene transf

153 The Sleeping Beauty (SB) transposon is a nonviral method of gene deli

154 The Sleeping Beauty (SB) transposon is a promising gene transfer vect

155 The Sleeping Beauty (SB) transposon is a Tc1/mariner family transposo

156 The Sleeping Beauty (SB) transposon is an emerging tool for transgene

157 The Sleeping Beauty (SB) transposon is an integrative nonviral plasmi

158 The Sleeping Beauty (SB) transposon mutagenesis screen is a powerful

159 cer (CRC) progression, we performed Sleeping Beauty (SB) transposon mutagenesis screens in mice carry

160 The Sleeping Beauty (SB) transposon mutagenesis system is a powerful

161 We used Sleeping Beauty (SB) transposon mutagenesis to identify events th

162 leukemia, we targeted cre-dependent Sleeping Beauty (SB) transposon mutagenesis to the blood-forming

163 Using Sleeping Beauty (SB) transposon mutagenesis, we identified novel

164 The Sleeping Beauty (SB) transposon represents an important vehicle f

165 o initiate leukemia, we performed a Sleeping Beauty (SB) transposon screen that identified cooperatin

166 (HO-1) rats) were generated using a Sleeping Beauty (SB) transposon system and extent of lesions over

167 The Sleeping Beauty (SB) transposon system can integrate foreign sequ

168 The Sleeping Beauty (SB) transposon system combines the advantages of

169 Over the past decade, the Sleeping Beauty (SB) transposon system has been developed as the

170 The Sleeping Beauty (SB) transposon system has been used as a somatic

171 The Sleeping Beauty (SB) transposon system has been used as an insert

172 The Sleeping Beauty (SB) transposon system is a nonviral DNA delivery

173 The Sleeping Beauty (SB) transposon system provides the first random

174 sly described an approach using the Sleeping Beauty (SB) transposon system to model hematopoietic mal

175 his study we utilized the non-viral Sleeping Beauty (SB) transposon system using the SB100X hyperacti

176 Recently, the Sleeping Beauty (SB) transposon system was shown to be useful for

177 The Sleeping Beauty (SB) transposon system was used to elucidate cand

178 nt non-viral approach combining the Sleeping Beauty (SB) Transposon System with selective proliferati

179 ene expression in pigs by using the Sleeping Beauty (SB) transposon system.

180 expression in rabbits by using the Sleeping Beauty (SB) transposon system.

181 The latest generation of Sleeping Beauty (SB) transposon vectors fulfills these requiremen

182 We used the Sleeping Beauty (SB) transposon, delivered as naked plasmid DNA b

183 ment and metastasis, we performed a Sleeping Beauty (SB) transposon-based forward genetic screen in m

184 ecently, two groups have shown that sleeping beauty (SB) transposon-based insertional mutagenesis can

185 s of MPNST development, we used the Sleeping Beauty (SB) transposon-based somatic mutagenesis system

186 Here we use Sleeping Beauty (SB) transposon-mediated insertional mutagenesis

187 Here we show that Sleeping Beauty (SB) transposon-mediated mutagenesis drives melan

188 tant allele of Apc (Apc(Min)) using Sleeping Beauty (SB) transposon-mediated mutagenesis.

189 were genetically modified using the Sleeping Beauty (SB) transposon/transposase system to express a C

190 We used the Sleeping Beauty (SB) transposon/transposase system to identify ac

191 ling of the piggyBac (PB), Tol2 and Sleeping Beauty (SB) transposons and the murine leukemia virus (M

192 preferential integration sites for Sleeping Beauty (SB) transposons into a particular 100 bp region

193 Mice harboring mutagenic Sleeping Beauty (SB) transposons were crossed with mice expressin

194 Here we show that Sleeping Beauty (SB), a member of the Tc1/mariner class of transp

195 However, since the resurrection of Sleeping Beauty (SB), the possibility of performing forward genet

196 ssion, through a human IDO-encoding Sleeping Beauty (SB)-based nonviral gene-integrating approach, ha

197 Finally, we show that Sleeping Beauty (SB)-HCC tumors evolve different antigenic/immuno

198 Forward genetic screens using Sleeping Beauty (SB)-mobilized T2/Onc transposons have been used

199 es in the IR/DR subgroup, including Sleeping Beauty (SB).

200 based on an engineered transposase, Sleeping Beauty (SB100X), delivered as an mRNA within a lipid nan

201 ficiencies of piggyBac, hyperactive Sleeping Beauty (SB11), Tol2, and Mos1 in four mammalian cell lin

202 l sparsity explains up to 28% of variance in beauty scores, and up to 47% when combined with a featur

203 BEAUTY searches of the NCBI and EMBL non-redundant prote

204 pharmacies, grocery stores, and cosmetic or beauty stores) in Baltimore, Maryland, and online.

205 cells genetically modified with the Sleeping Beauty system to express D-CAR stably were propagated se

206 We used electrotransfer of Sleeping Beauty system to introduce a CAR transposon and selectiv

207 ed T cells were generated using the Sleeping Beauty system to stably introduce the CD19-specific CAR

208 The Sleeping Beauty system was used to deliver microRNA-15a/16-1 into

209 ercome this constraint, we used the Sleeping Beauty transposable element to achieve chromosomal integ

210 e transcription unit expressing the Sleeping Beauty transposase (SB) and another expressing human uri

211 The Sleeping Beauty transposase (SB) was constructed on the basis of

212 PiggyBac or Sleeping Beauty transposase bigenic rats bred with wild-type albi

213 Sleeping Beauty transposase binds to the inverted repeats of salm

214 We show that the Sleeping Beauty transposase can efficiently insert transposon DNA

215 in-deleted canine FVIII in cis with Sleeping Beauty transposase in hyaluronan nanocapsules and inject

216 6 E6/E7-luciferase, AKT, c-myc, and Sleeping Beauty transposase into the cervicovaginal tract of C57B

217 uitously express either piggyBac or Sleeping Beauty transposase were generated by standard zygote inj

218 coexpress the Etv6-RUNX1 fusion and Sleeping Beauty transposase.

219 housands of genomic sites using the Sleeping Beauty transposase.

220 tructed by ligating the CMV-driven "Sleeping Beauty" transposase gene downstream to the Tc1-like tran

221 sposition but were inactive against Sleeping Beauty transposition and long interspersed nucleotide el

222 For example, the Sleeping Beauty transposon (SB) can transform a wide range of ver

223 Sleeping Beauty transposon (SB-Tn) has emerged as an important no

224 -CA) with mice in which a mutagenic Sleeping Beauty transposon (T2/Onc) was mobilized only in B cells

225 ng these mice with those carrying a Sleeping Beauty transposon array.

226 Using the Sleeping Beauty transposon as a delivery system, we introduced an

227 l of this approach, we encapsulated Sleeping Beauty transposon expressing the B domain-deleted canine

228 For example, the Sleeping Beauty transposon has become highly instrumental to indu

229 Mobilizing the Sleeping Beauty transposon in cerebellar neural progenitor cells

230 ted this hypothesis by performing a Sleeping Beauty transposon mutagenesis screen in which common ins

231 We used it to perform a Sleeping Beauty transposon mutagenesis screen to identify genes t

232 A new study uses Sleeping Beauty transposon mutagenesis to drive osteosarcomagenes

233 An unbiased Sleeping Beauty transposon screen revealed MyoD as a putative med

234 dentified in previous retroviral or Sleeping Beauty transposon screens, including Spic, which encodes

235 y shows for the first time that the Sleeping Beauty transposon system can be used to identify candida

236 uced pluripotent stem cells using a Sleeping Beauty transposon system carrying the micro-utrophin gen

237 d insertional mutagenesis using the Sleeping Beauty transposon system in mice carrying germline or so

238 tional mutagenesis screen using the Sleeping Beauty transposon system in mice with mammary-specific i

239 sorders have shown efficacy for the Sleeping Beauty transposon system in the treatment of hemophilia,

240 factor in prostate cancer, and the Sleeping Beauty transposon system is a useful tool for identifyin

241 ional mutagenesis indicate that the Sleeping Beauty transposon system may be a safer alternative than

242 in Nature, Sun et al. (2014) used a sleeping beauty transposon system to demonstrate that natural hem

243 ing insertional mutagenesis via the Sleeping Beauty transposon system, combined with long-read nanopo

244 the mouse and the rat, by using the Sleeping Beauty transposon system.

245 Thus, Sleeping Beauty transposon targeted to liver sinusoidal endotheli

246 Here we report the ability of the Sleeping Beauty transposon to act as a somatic insertional mutage

247 injected with AKT/Ras or c-Myc and Sleeping Beauty transposon to induce HCC.

248 rodynamically codelivered using the Sleeping Beauty transposon to initiate liver tumorigenesis.

249 ation of a single-copy inactivating Sleeping Beauty transposon to Pten disruption within the same gen

250 liary tract was accomplished by the Sleeping Beauty transposon transfection system with transduction

251 A Sleeping Beauty transposon, engineered to elicit loss-of-function

252 entivirus, PiggyBac transposon, and Sleeping Beauty transposon, in aggregate >108,000 vector permutat

253 g the local hopping activity of the Sleeping Beauty transposon, the lacZ reporter gene was dispersed

254 e identified such mutations using a Sleeping Beauty transposon, which caused rapid-onset AML in 80% o

255 A hybrid piggyBac/Sleeping Beauty transposon-based insertional mutagenesis system t

256 In this study, we conducted a Sleeping Beauty transposon-mediated insertional mutagenesis scree

257 a novel tyrosinase minigene-tagged Sleeping Beauty transposon-mediated mutagenesis, which allows for

258 netic screen in Emu-TCL1 mice using Sleeping Beauty transposon-mediated mutagenesis.

259 ed human PAX7+ satellite cells with Sleeping Beauty transposon-mediated nonviral gene transfer, highl

260 ted throughout the genome using the Sleeping Beauty transposon.

261 expressed in p53fl/fl mice using a sleeping beauty transposon.

262 using ex vivo mutagenesis with the Sleeping Beauty transposon.

263 hMet and mutant-beta-catenin using sleeping beauty transposon/transposase leads to hepatocellular ca

264 , introducing DNA plasmids from the Sleeping Beauty transposon/transposase system to directly express

265 MA148 was genetically modified by "Sleeping Beauty" transposon-mediated delivery of DsRed2 fluoresce

266 Sleeping Beauty transposons have the potential for use as chromos

267 ce and forward genetic screens with Sleeping Beauty transposons implicate additional signaling cascad

268 Mobilization of Sleeping Beauty transposons in NSCs induced the immortalization o

269 nts, which were further deployed by Sleeping Beauty transposons throughout the genome of human bone e

270 have also been developed to deliver Sleeping Beauty transposons to the lung, liver and tumors for tre

271 Truth may be beauty, and beauty truth, in more than a metaphorical sense, and fal

272 (WEs) and East Asians (EAs) evaluate facial beauty using culture-specific features, contradicting th

273 These results support the use of Sleeping Beauty vectors in carrying an insulated IHK-beta-globin

274 mportance of an image statistic to perceived beauty was not related to how closely art reproduces the

275 and face to face) among UK salons (hair and beauty) was conducted.

276 o construct a synthetic transposon, Sleeping Beauty, which could be identical or equivalent to an anc

277 i nc (tobacco), and Cucurbita pepo cv. Black Beauty (zucchini).