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1 ed to prolonged SERCA activation, presumably because 14-3-3 protected PLN pentamers from dephosphoryl
3 y of this key GTPase in cancer, particularly because a large number of cancer cell lines with charact
4 health care, use of TM is likely to increase because a large part of the move to adopt TM is driven b
5 the importance of accurate head positioning, because a slight change in head position resulted in ina
6 nt chemistry's challenging synthetic targets because a three-dimensional assembly is necessary for th
7 mental stressors not only for a few species, because an effect may be positive in one species but neg
14 t; however, treatment typically occurs later because biliary atresia is difficult to detect during it
15 growth on later-life cardiometabolic disease because birth weight is only a crude indicator of fetal
20 ically reduced their calf losses by cheetahs because cheetahs did not follow the herds but instead pr
22 nd thermodynamics of biochemical conversions because CO(2) is an intermediate and end-product of the
26 in vivo in C. trachomatis We reasoned that, because DapF (Ct) utilizes a shared substrate-binding si
27 PE or CPOs is better but still insufficient, because different carbapenemases have differing treatmen
28 ies engineer the climate, conflict can arise because different countries might prefer different tempe
29 pants, and interpretation can be challenging because different variants and genes were highlighted by
30 ibuted conclusively to a change in ownership because differential improvement occurred before acquisi
32 hundreds of millions of years, is entrenched because exposure of this interface to solvent reduces pr
33 hment of colonizing zooplankton populations, because fish preferentially consume larger species that
36 ion rather than electron-driven dissociation because glycan-retaining peptide fragments would not be
37 tteries are limited by electrolyte selection because high ionic conductivity and poor electrochemical
38 y troponin interactions on actin-tropomyosin because high-resolution experimentally determined struct
40 model for studying how RNA triggers disease because: (i) Affected tissue is routinely removed during
41 does not always reflect its activity state, because interventions such as inhibitors or mutations ca
42 nd painless procedure that is well tolerated because it avoids rectal trauma and patients recover imm
43 ng is essential to many biological processes because it builds high-affinity bonds by using several w
44 ption for the treatment of infrabony defects because it can improve both tooth retention rate and ove
46 to nCV, but cnCV has much shorter run times because it does not construct classifiers in the inner f
47 ontrol and public health in tropical regions because it enables the development of instantaneous upda
48 mportant building block in organic synthesis because it features several reaction sites with nucleoph
51 lization is notoriously difficult to control because it is exquisitely sensitive to monomer concentra
52 eads to many unnecessary surgical procedures because it is not possible to assure the benignity of th
53 roportionation lacks technological relevance because it occurs only under specific physical condition
54 ited to micromolar levels in the environment because it precipitates with calcium as low-solubility a
55 carotenoids has attracted a lot of interest because it provides an understanding of their oxidative
56 eeism in nursing is particularly significant because it puts patients at risk by reducing the capacit
58 HEJ has the potential to be highly mutagenic because it uses DNA polymerases, nucleases, and other en
59 le ends, to which KIF5B binds poorly, likely because its cofactors, MAP7-family proteins, are slow in
64 noninvasive genetic samples are inefficient because lower-quality samples cannot be used, and they a
68 in is an appropriate model for these viruses because many target cells are present, including basal k
69 use of large numbers of detectable taxa, and because microbiota characteristics are described in rela
75 ment concentrations typically remain unknown because nonsuitable sample stabilization and chromatogra
76 pregnancy, is prevalent; this is of concern because observational studies have shown negative associ
77 It has been argued that psychosis may emerge because of a failure to learn sensory statistics, result
78 or into deeper water when temperatures rise because of barriers, reduced light availability, altered
79 immense physical and psychological symptoms because of both their illness and often intensive treatm
80 is a perpetual concern in Arctic communities because of challenging climatic conditions, limited opti
81 murine b-wave in both genotypes, most likely because of chelating amino acids present in the murine n
82 et negative charges appeared self-inhibitory because of ClC-5's voltage-gated properties, but shunt c
83 uld not have met ZUMA-1 eligibility criteria because of comorbidities at the time of leukapheresis.
86 ntingent on early community states, not only because of differences in the species pool, but also bec
88 est stages of the CD8(+)T(M) recall response because of expeditious synthesis/secretion kinetics (CCL
89 years after his first facial transplantation because of extensive disfigurement from type 1 neurofibr
90 sm type 2 (OCA2) is a gene of great interest because of genetic variation affecting normal pigmentati
91 ophenes bearing reactive groups is difficult because of high reactivity of organometallic reagents.
92 45% of 1103 United States kidneys discarded because of histologic findings could be accurately match
95 esearch data do not provide database matches because of informatic artifacts, chemical contaminants,
96 chniques have limitations, particularly APT, because of insufficient understanding of void imaging.
97 ransforming growth factor beta 1 (TGF-beta1) because of interleukin-4 (IL-4)- and signal transducer a
102 al 2D material predicted to be piezoelectric because of its highly directional properties and non-cen
105 cancer (PC) remains a therapeutic challenge because of its intrinsic and extrinsic chemoresistance m
108 ZBP1 is unique among innate immune sensors because of its N-terminal Zalpha1 and Zalpha2 domains, w
110 ion among different data-sources is reliable because of its potential of unveiling new functionalitie
113 of treatment in adoptive cell therapy (ACT) because of its protumor effects and its role in the cyto
114 is of HCM-LVSD has reportedly been poor, but because of its relative rarity, the natural history rema
116 oved to be a promising tool for targeted EMB because of its sensitivity and specificity for identific
119 Ubiquitin was chosen as the model protein because of its structural stability which allows the pro
120 difference in chloroplast morphology, likely because of K redistribution from vacuole to chloroplast.
121 ds (44.4%) or a high suspicion of malignancy because of known pre-existing systemic malignancy or the
122 riation, but such calibrations are precluded because of lack of experimental relative permeability da
124 DNA sequencing are complex and compositional because of large numbers of detectable taxa, and because
125 le in rejection is unknown, however, in part because of limited techniques for distinguishing recipie
126 enome sequencing of specimens is challenging because of low bacterial and high human DNA abundances.
127 lthough phylogenetic clustering is uncertain because of low virus genetic variation early in the pand
128 emodeling in which pulmonary arteries narrow because of medial thickening and occlusion by neointimal
130 sis and phosphorylate most mitotic proteins, because of parallel PP2A:B55 phosphatase inactivation by
131 th a 2-fold increased odds of being referred because of photography findings compared with standard c
132 pharmacogenetic studies is often challenging because of poor reporting of key data in study reports.
133 ses severe disability and death of young men because of progressive muscle degeneration aggravated by
135 or cells, while IgE-ICs were noninflammatory because of reduced FcepsilonRI binding and enhanced CD23
136 , particularly type 2 myocardial infarction, because of respiratory failure with hypoxia and hemodyna
137 However, patient access remains limited because of restricted insurance coverage and a lack of g
138 de patients who are at high immunologic risk because of sensitization to alloantigens, including thos
139 design is preferable over monolithic sensors because of simpler assay optimization and improved selec
141 modified clones; this is usually challenging because of sparse sampling of the various cell types dur
142 mice are not readily infected by SARS-CoV-2 because of species-specific differences in their angiote
143 icted to affect wild organisms, particularly because of the central role that light regimes play in d
144 degradation products has proven challenging because of the complexity, transience, and low concentra
146 difficult to localize by conventional means because of the difficulty in specific targeting/delivery
147 butene-1,2-dione from 2-diazo-1,3-indandione because of the difficulty of inducing the initial rearra
148 diction of plant gas exchange is challenging because of the diversity of biological components regula
149 ced number of circulating white blood cells, because of the Duffy-null (CC) genotype at rs2814778 in
150 patient, enteric derivation was not possible because of the extremely fragile intestinal tissue perio
151 rts have focused on those aspects, primarily because of the few animal models available as natural ho
153 0) crystallographic plane of the Li crystals because of the fine in-plane lattice matching between Li
155 ion enzymology has evaded detailed analysis, because of the historical unavailability of kinetically
156 is aggressive with a poor prognosis, partly because of the immunosuppressive microenvironment create
157 tibiotics for these pathogens is challenging because of the inability of most small molecules to accu
158 DGAT2's acyl-donor specificity is not known because of the inherent challenges of predicting structu
159 ations have experienced declines of over 90% because of the introduced fungal pathogen that causes wh
160 aments are less stable than the ScRad51 ones because of the kinetically much reduced nucleation step.
162 sites for NRR catalysis remains challenging because of the large distance between them, which signif
163 s to adult facilities is also a complex task because of the large number of distinct disorders, which
164 ever, the three studies were not independent because of the large overlap in their participants, and
165 ures of perfect absorption could be observed because of the localized surface plasmon resonance that
166 eptible to the low arginine microenvironment because of the low expression of the arginine resynthesi
168 ng useful mathematical models is challenging because of the often different domains of knowledge requ
169 ve heat transfer in the ambient environment, because of the overlap with the atmospheric transmission
170 ion (TACE) in hepatocellular carcinoma (HCC) because of the potential for profound adverse events and
171 effects of contaminants remains challenging because of the sheer number of chemicals and their ambig
174 arantine, and population-level interventions because of the specific transmission kinetics of this vi
175 anically bound Fe dominates with this effect because of the strong dependency of iron oxyhydroxide so
177 passive, and heterogeneity may be increased because of the underlying pathophysiology leading to Fon
178 simply infeasible for many taxa and settings because of the vast numbers of animals involved-hundreds
179 ce infection is established, and this may be because of the very early formation of a reservoir of la
181 a spin splitting and anomalous Hall effects, because of their characteristic layered structures compo
183 hingolipid metabolites have gained attention because of their essential role in the pathogenesis and
184 gnetic systems have been studied for decades because of their extraordinary properties and promising
185 mental waters is an alarming issue, not only because of their harmful effects in the environment but
191 has mainly focused on redox-active proteins because of their role in biological charge transport.
193 ations are an interesting part of this group because of their tendency to undergo rearrangement, some
198 of age, at which point she was hospitalized because of three syncopal episodes that were not related
201 egions have higher local richness not simply because older pools are more speciose but also because s
202 ke et al. in Ecol Evol 9:10734-10745, 2019), because one parent can benefit by mating with a new part
204 ve important implications for cancer biology because oxidized purines in the nucleoside pool can sign
205 erapy or to improve radiotherapy have failed because oxygenation protocols were not combined with imm
212 to address religious and cultural concerns, because porcine and bovine gelatins are prohibited in Ha
213 lective probes for individual SHs are scarce because probe synthesis usually takes place by time-cons
214 patients with glioblastoma is controversial because progression-free survival benefit did not transl
215 e sensitivity was not limited to TP receptor because prostaglandin F receptor activated with U46619 a
218 egarding the impact of 12 h shifts may arise because research is conducted in divergent contexts.
219 ver, this conclusion was recently challenged because residual uncorrected stratification from large-s
220 y RTN triggers active expiration, presumably because RTN, unlike C1, has direct excitatory projection
225 cause older pools are more speciose but also because species have evolved traits that allow them to l
226 persal across species remain unclear, partly because standardised estimates of dispersal ability are
228 od ingredients with anti-diabetic properties because strong alpha-amylase inhibition generally causes
231 using conventional approaches is challenging because the available materials at these scales are not
234 vioral and neural effects have been puzzling because the compounds target distinct molecular receptor
236 sidered to be the deadliest animals on Earth because the diseases they transmit claim at least a mill
237 of the solvent molecules must be understood because the electrochemical properties of a solvent can
238 yields complex populations of materials, and because the elements H, C, O, and N are among the most a
242 e His complex (PHC) will always perturb AVRT because the His bundle is obligatory to the circuit.
244 apture as much as 30-60% of a school at once because the increase in their apparent (visual) size doe
245 ered precautionary for forage species simply because the limit is a small proportion of the species'
247 is in cases analyzed without microdissection because the majority of sequences were contaminants.
248 influence mammographic features is important because the mechanisms through which they are associated
249 terization of these materials is challenging because the metal atoms reside on surfaces that are typi
250 defects are the most challenging to classify because the minimal level of full-length (FL) transcript
251 arget opioid use, misuse, and addiction, but because the opioid crisis includes multiple substances,
253 urrences of zoster ophthalmicus are uncommon because the reactivation efficiently boosts anti-VZV imm
254 of differences in the species pool, but also because the same species have different dynamics in diff
255 oncentration, yielding predictable switching because the statistical ensemble behavior of oxygen vaca
256 with accuracies ranging from 85.5 to 88.0%, because the top discriminatory metabolite biomarkers fro
259 ng specific 5,10-diheterotruxene derivatives because the universal method suitable for obtaining mole
260 concern to food regulators around the world because these compounds have been associated to acute an
261 tage of traditional summer research programs because these programs require students to relocate or b
262 hat these subtypes are biologically relevant because they appear to have distinct genetic architectur
263 can be successfully applied in this setting because they are a powerful tool to analyze data with la
264 ary means to probe these polymers, precisely because they are sensitive to different aspects of molec
267 Many livestock and human vaccines are leaky because they block symptoms but do not prevent infection
268 battery electrode deionization (BDI) systems because they can achieve selective ion removal and low e
269 ofluids (e.g., sweat), play a critical role, because they can be deployed at a large scale to monitor
270 retained their ability to sense alloantigen because they continued to drive T cell maturation into C
272 ARM1 may make worthwhile therapeutic targets because they did not have genetically predicted effects
274 tructures presented in this study are unique because they exhibit three distinct helical states, two
275 cy of vaccines expressing alpha-Gal epitopes because they express alpha-Gal epitopes and lack anti-Ga
277 ole-body MRI, two participants were excluded because they had clinical progression before imaging sho
279 of amphipathic components of plasma membrane because they may serve as interaction, condensation, and
282 results suggest that we use rules, in part, because they reduce the costs of decision-making through
283 se arachnids are ideal to examine this topic because they show high levels of leg loss in the field b
284 also required cDC1, and this was not simply because they transport antigens to lymph nodes for proce
285 al proofreading schemes, however, is limited because they typically require dedicated structural feat
286 r-catalyzed MCRs are particularly attractive because they use a relatively abundant and non-toxic cat
287 ithms have limited predictive power, in part because they were not trained on high-quality epitope da
288 ) of the proteolytic cleavage site of MuV F, because this amino acid residue shows a striking variabi
289 nuously values declared for prepacked foods, because this information is crucial for consumers and fo
290 t logging influences phosphorus (P) cycling, because this scarce nutrient is removed in extracted tim
293 This benefit can extend to a large region because two thirds of patients treated at KHCC were non-
295 identify individuals having these disorders because, unlike patients with sporadic cancer, these pat
297 graphic convergence is particularly striking because while the dynamics of biological and cultural ev