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1 sidered unsuitable for standard chemotherapy because of a cardiac ejection fraction of less than 50%,
2 ve decline and is thought to arise, in part, because of a chronic pro-inflammatory state in the brain
3 . crescentus MreB over Escherichia coli MreB because of a closer match in the degree of opening with
4 It has been argued that psychosis may emerge because of a failure to learn sensory statistics, result
5 dy brings about resistance to chemotherapies because of a general feature of the aneuploid condition-
6 anged from one visual hemifield to the other because of a horizontal saccadic eye movement.
7 he facial and/or spinal accessory nerves and because of a likely margin-positive (R1 or R2) result.
8  clades achieved higher relative brain sizes because of a reduction in body size.
9                          This alteration was because of a reduction in the levels and activity of a r
10                                              Because of a scarcity of functional studies and poor und
11 ransplant in the United States are discarded because of abnormal histology.
12 -old who discontinued treatment after 3 days because of "abnormal drug taste." The most commonly repo
13  be killed by developmental alcohol exposure because of activation of microglial immune cells in the
14 anisms has in particular remained unexplored because of additional experimental limitations.
15 static cancer have extended overall survival because of advanced therapies.
16                 Remdesivir was stopped early because of adverse events in 18 (12%) patients versus fo
17 eased in adar- and eri-6/7-defective mutants because of an antiviral RNAi response to dsRNA.
18 g motif shown in experiments, but it rotates because of an electrostatic repulsion and forms a hydrop
19 gue that current drugs for AF are inadequate because of an oversimplified system for patient classifi
20 blockers reduce migration and invasion rates because of autophagy blockade only in BRAF(V600E)-mutant
21  or into deeper water when temperatures rise because of barriers, reduced light availability, altered
22 .5 y old) who underwent (68)Ga-PSMA11 PET/CT because of biochemically recurrent PC.
23  immense physical and psychological symptoms because of both their illness and often intensive treatm
24 tivity are difficult to study experimentally because of challenges in isolating a particular phosphor
25 s at large scale, but not mosquitoes, mainly because of challenges with consistent production and dis
26 is a perpetual concern in Arctic communities because of challenging climatic conditions, limited opti
27 murine b-wave in both genotypes, most likely because of chelating amino acids present in the murine n
28 et negative charges appeared self-inhibitory because of ClC-5's voltage-gated properties, but shunt c
29 uld not have met ZUMA-1 eligibility criteria because of comorbidities at the time of leukapheresis.
30 cancer in this population can be challenging because of competing health and ageing-related condition
31 d then single-cell sequence such populations because of compounding losses.
32 isinin monotherapy, which is not recommended because of concerns regarding parasite resistance.
33 mage and decline of cardiac function, likely because of dampened activation of cytotoxic CD8(+) T cel
34 nal support in medical and academic settings because of deficits in various EF domains.
35 developing antiicing surfaces remain elusive because of degradation such as mechanical wearing.
36            Exposure to chronic hyperglycemia because of diabetes mellitus can lead to development and
37  compared with local field potential was not because of differences in low-level visual features capt
38 ntingent on early community states, not only because of differences in the species pool, but also bec
39 ay have caused some discrepancy in VL values because of different limits of detection.
40 molecular details are only partly understood because of difficulties with experimentally accessing th
41                                              Because of earlier findings that ~90% of global ribozyme
42              Asthma may limit imaging for PE because of either worsened ventilation defects on ventil
43 rk as effectively in female mice as in males because of estrogen regulation of G protein receptor kin
44 est stages of the CD8(+)T(M) recall response because of expeditious synthesis/secretion kinetics (CCL
45 years after his first facial transplantation because of extensive disfigurement from type 1 neurofibr
46 ory epithelium, the organ of Corti, vibrates because of external and internal excitations.
47 tients may still face progressive disability because of failure of myelin regeneration and loss of ne
48                                              Because of FD numerically showing changes in bone trabec
49        Higher frequency populations do exist because of frequent first-cousin marriages and/or a high
50 how signs of deeper evolutionary integration because of functional, developmental or genetic constrai
51 sm type 2 (OCA2) is a gene of great interest because of genetic variation affecting normal pigmentati
52 pecies lack putrescine biosynthetic pathways because of genomic decay.
53 ls from biorenewable and sustainable sources because of great concerns about the environment, waste a
54                                              Because of high anthocyanin content and higher bioactive
55 ns under paced in deployment efforts, mainly because of high costs.
56 growth in private insurers' overhead, mostly because of high overhead in their Medicare and Medicaid
57 ophenes bearing reactive groups is difficult because of high reactivity of organometallic reagents.
58  45% of 1103 United States kidneys discarded because of histologic findings could be accurately match
59                                              Because of HIV's vast sequence diversity, the ability of
60 ntervention arm could not complete the trial because of hypotension.
61                                              Because of increasing access to and use of cannabis in t
62 ammatory disease of the heart that may occur because of infections, immune system activation, or expo
63 esearch data do not provide database matches because of informatic artifacts, chemical contaminants,
64 chniques have limitations, particularly APT, because of insufficient understanding of void imaging.
65  anthracene-substituted derivatives, perhaps because of inter-arene torsions that emerge in theoretic
66 ransforming growth factor beta 1 (TGF-beta1) because of interleukin-4 (IL-4)- and signal transducer a
67           Bespoke reagents are commonly used because of issues associated with the low reactivity of
68 iagnosed on CT angiography (CTA) of the neck because of its ability to resolve calcium and create mul
69 of increase in brain Asp and NAA is possibly because of its active utilization by the aralar-KO brain
70  portion is higher (26%) in central Auckland because of its better road network connectivity.
71 been paid to magnetic particle imaging (MPI) because of its better sensitivity compared to MRI.
72 ere for engineering higher-valency molecules because of its compact size, simple structure, and natur
73 hment and function of the TME remain obscure because of its complex cellular composition.
74 uced bioactivity compared with WT GH (GH-WT) because of its decreased ability to bind and activate th
75 cterization of proteins by mass spectrometry because of its distinct fingerprint pattern.
76 al and biotechnological applications, mainly because of its effects on the cell plasma membrane, but
77 rus (AAV) is a promising gene therapy vector because of its efficient gene delivery and relatively mi
78  most widely used proteases in biotechnology because of its exquisite sequence specificity.
79 anding potential applications in biomedicine because of its high electrical conductivity and biocompa
80      It is concerning to health care workers because of its high mortality rate, due primarily to its
81 en observed indirectly in the gas phase, and because of its high reactivity has eluded isolation in t
82 al 2D material predicted to be piezoelectric because of its highly directional properties and non-cen
83                                              Because of its immunomodulatory function, CD40L has been
84                                              Because of its impact in the immune system, we investiga
85  cancer (PC) remains a therapeutic challenge because of its intrinsic and extrinsic chemoresistance m
86 enerated a lot of interest among researchers because of its involvement in both the normal aging proc
87                                              Because of its involvement in synaptic plasticity, SynGA
88                                              Because of its longevity and enormous information densit
89 he tumor microbiome has remained challenging because of its low biomass.
90   ZBP1 is unique among innate immune sensors because of its N-terminal Zalpha1 and Zalpha2 domains, w
91                                              Because of its narrow host range - limited to Vitis spec
92 ect-targeting of c-Myc poses special problem because of its non-enzymatic nature and certain amount o
93                 VEEV is a biodefence concern because of its potential for aerosol spread and the curr
94 ion among different data-sources is reliable because of its potential of unveiling new functionalitie
95 to one of its two isoforms, GSK3beta, simply because of its prevalent expression in the brain.
96 as gained a considerable amount of attention because of its promising pharmacological effects.
97  of treatment in adoptive cell therapy (ACT) because of its protumor effects and its role in the cyto
98                                              Because of its recent emergence, there is a paucity of i
99 is of HCM-LVSD has reportedly been poor, but because of its relative rarity, the natural history rema
100                                              Because of its remarkable stress tolerance and intense f
101                        Our study was limited because of its restricted geographic scope, small sample
102 oved to be a promising tool for targeted EMB because of its sensitivity and specificity for identific
103  skeletal myosin is particularly challenging because of its similarity to the cardiac isoform.
104 T182I resided predominantly on mitochondria, because of its slow retrotranslocation and mediated apop
105 tive therapy (IPT) may revert LTBI diagnoses because of its sterilizing activity.
106    Ubiquitin was chosen as the model protein because of its structural stability which allows the pro
107 est electrophysiologically studied jellyfish because of its system of giant axons and unique fast swi
108 difference in chloroplast morphology, likely because of K redistribution from vacuole to chloroplast.
109 ds (44.4%) or a high suspicion of malignancy because of known pre-existing systemic malignancy or the
110  a planned analysis of the first 10 patients because of lack of efficacy.
111 riation, but such calibrations are precluded because of lack of experimental relative permeability da
112 ed it to 2.7 +/- 0.2 kg CO(2) eq per kg milk because of land use change emissions.
113 DNA sequencing are complex and compositional because of large numbers of detectable taxa, and because
114 visual features captured by them but instead because of larger spatial summation of the ECoG.
115 declines have offset energy efficiency gains because of LEPA adoption.
116 ransplantation outcomes is poorly understood because of limitations of conventional SES measures.
117                                              Because of limited investigation of demethylation-induce
118 econdary sources, has been uncertain in part because of limited knowledge of the precursor emissions
119 le in rejection is unknown, however, in part because of limited techniques for distinguishing recipie
120 adrant US examinations were mostly performed because of liver laboratory findings (87%, 32 of 37), an
121                                              Because of logistical difficulties with cryotherapy (eg,
122 ondria aggregate and depolarize after stress because of loss of activity of the mitochondrial fission
123 y, and six (17%) discontinued it prematurely because of loss to follow-up, withdrawal of consent, inv
124 enome sequencing of specimens is challenging because of low bacterial and high human DNA abundances.
125 lthough phylogenetic clustering is uncertain because of low virus genetic variation early in the pand
126 gained are not always translatable to humans because of major species differences.
127 emodeling in which pulmonary arteries narrow because of medial thickening and occlusion by neointimal
128 rolled patients did not undergo the protocol because of medical complications unrelated to the study
129 to and mixes with POPC, also an inverse cone because of mobility of its unsaturated tail.
130 eye (0.3%) changed diagnosis from PIC to MFC because of newly developed peripheral lesions.
131                                        Also, because of nonlinear production chemistry and titration
132 ed large challenges to energy quantification because of nonlinearities.
133 tive pollen tube growth and seed development because of nonviable mutant gametes.
134      Diagnosis of alveococcosis is difficult because of not typical clinical picture and irregular re
135 f Aleutian kelp forests, are rapidly eroding because of overgrazing by herbivores.
136 sis and phosphorylate most mitotic proteins, because of parallel PP2A:B55 phosphatase inactivation by
137                                     However, because of peak overlap and peak shifting, the available
138 uronal function and survival remains unclear because of perinatal lethality exhibited by knockout mic
139  novo monogenic neurodevelopmental disorders because of phenotypic heterogeneity and the absence of l
140 th a 2-fold increased odds of being referred because of photography findings compared with standard c
141  in low diversity communities and especially because of plant diversity loss in initially high divers
142 ives as therapeutic agents has been hampered because of poor drug-like properties as well as syntheti
143  Of 210 subjects recruited, 23 were excluded because of poor quality UBM images.
144 pharmacogenetic studies is often challenging because of poor reporting of key data in study reports.
145        Equally, avoiding essential treatment because of potential fetal harm risks a poor outcome for
146 ses severe disability and death of young men because of progressive muscle degeneration aggravated by
147 zing replication fork stalling likely occurs because of proteins bound to the R-loops.
148 icity of both CT and (18)F-FDG PET/CT is low because of radiation-induced changes.
149 or cells, while IgE-ICs were noninflammatory because of reduced FcepsilonRI binding and enhanced CD23
150 ome countries and might not be generalisable because of regional differences in health-care infrastru
151 n health-care systems and society as a whole because of repeated consultations, unnecessary investiga
152 tenuated DOX-induced cardiac atrophy, likely because of repression of muscle RING finger 1 (MuRF1), a
153 , particularly type 2 myocardial infarction, because of respiratory failure with hypoxia and hemodyna
154      However, patient access remains limited because of restricted insurance coverage and a lack of g
155 de patients who are at high immunologic risk because of sensitization to alloantigens, including thos
156 design is preferable over monolithic sensors because of simpler assay optimization and improved selec
157         The trial was terminated prematurely because of slower-than-expected recruitment and funding
158 ish in their magnitude over time, especially because of soil acidification in low diversity communiti
159 modified clones; this is usually challenging because of sparse sampling of the various cell types dur
160  mice are not readily infected by SARS-CoV-2 because of species-specific differences in their angiote
161 ality failed to be statistically significant because of survey design or because participants use heu
162                                              Because of systematic differences in access to care, cos
163                                              Because of the ability to rapidly generate metabolite-bi
164 icted to affect wild organisms, particularly because of the central role that light regimes play in d
165 either load-free or constant load conditions because of the complexity of the equipment required for
166  degradation products has proven challenging because of the complexity, transience, and low concentra
167 radictory results have been reported, mainly because of the complicated trap states characteristic of
168                                              Because of the costs of clinical and experimental studie
169 esidential declaration of national emergency because of the COVID-19 pandemic.
170  bilayers, which form moire superlattices(6) because of the difference between the lattice constants
171 ly active heterosurfaces remains a challenge because of the difficulty in component tuning, morpholog
172  difficult to localize by conventional means because of the difficulty in specific targeting/delivery
173 rs in extinct vertebrates is rare, primarily because of the difficulty of identifying such behaviors
174 butene-1,2-dione from 2-diazo-1,3-indandione because of the difficulty of inducing the initial rearra
175                                     Further, because of the difficulty of studying pregnant patients,
176 studies, however, are inherently problematic because of the discovery of excessive false positive (FP
177                                              Because of the diverse contexts in which placebo or sham
178 diction of plant gas exchange is challenging because of the diversity of biological components regula
179 ced number of circulating white blood cells, because of the Duffy-null (CC) genotype at rs2814778 in
180 e kappa(latt) by effective phonon scattering because of the excess point defects and rich microstruct
181 patient, enteric derivation was not possible because of the extremely fragile intestinal tissue perio
182                                              Because of the favorable outcome of most patients with C
183 rts have focused on those aspects, primarily because of the few animal models available as natural ho
184 ents, and woody aroma profile did not change because of the film-treatment.
185 0) crystallographic plane of the Li crystals because of the fine in-plane lattice matching between Li
186                                              Because of the high coverage of international vaccinatio
187                                              Because of the high selectivity of the sensor, we were a
188                                              Because of the high transmissibility of the virus and th
189  represents an attractive treatment strategy because of the high-linear-energy transfer and short pat
190 ion enzymology has evaded detailed analysis, because of the historical unavailability of kinetically
191  is aggressive with a poor prognosis, partly because of the immunosuppressive microenvironment create
192 evel II, and 13 studies were rated level III because of the impact on the development and popularizat
193 tibiotics for these pathogens is challenging because of the inability of most small molecules to accu
194 ens as data are aggregated over larger areas because of the increasing diversity among farms, but at
195 phagocytic activity, both likely compromised because of the induction of antibodies that did not bind
196  DGAT2's acyl-donor specificity is not known because of the inherent challenges of predicting structu
197 ations have experienced declines of over 90% because of the introduced fungal pathogen that causes wh
198 aments are less stable than the ScRad51 ones because of the kinetically much reduced nucleation step.
199                                              Because of the lack of a standard definition for HFrecEF
200 hogenesis research has been greatly hindered because of the lack of an animal model.
201 ted systematically on this class of proteins because of the lack of an appropriate benchmark set.
202 d with caution, perhaps sparingly, primarily because of the lack of enough training data and computat
203                                     However, because of the lack of suitable tools, little spatiotemp
204  sites for NRR catalysis remains challenging because of the large distance between them, which signif
205 s to adult facilities is also a complex task because of the large number of distinct disorders, which
206 ever, the three studies were not independent because of the large overlap in their participants, and
207 nning patients in the first 2 d of treatment because of the larger degree of tracer clearance in this
208                                              Because of the limited availability of this MRI techniqu
209  unusual properties of water remains elusive because of the limited data at the temperatures and pres
210                   Here, we question whether, because of the limited sustainable supply of biomass, BE
211 ures of perfect absorption could be observed because of the localized surface plasmon resonance that
212 eptible to the low arginine microenvironment because of the low expression of the arginine resynthesi
213 s, the correlation was low (<0.80) primarily because of the low numbers of events recorded in these s
214                                              Because of the low sensitivity, targeting individuals in
215 ons remain a leading threat to global health because of the misuse of antibiotics and the rise in dru
216                                              Because of the need for increased knowledge regarding th
217  elective cancer surgery has become an issue because of the need to balance the requirement to treat
218 ng useful mathematical models is challenging because of the often different domains of knowledge requ
219 g receptors leads to LL HC hyperpolarization because of the opening of small-conductance Ca(2+)-activ
220                                              Because of the overexpression of Aurora kinases in a bro
221 ve heat transfer in the ambient environment, because of the overlap with the atmospheric transmission
222 , the presence of arsenic can be problematic because of the potential for increased mobilization and
223 ion (TACE) in hepatocellular carcinoma (HCC) because of the potential for profound adverse events and
224 tion carried a substantial risk of morbidity because of the potential need to sacrifice the facial an
225 ons were less stable than in C(H)2s and m01s because of the presence of the N-terminal 3(10)-helix an
226                                     However, because of the prominent mitotic phenotype upon NuMA los
227                                              Because of the rarity and aggressive nature of malignant
228 etic compartment reconstitution was improved because of the recovery of the supportive stromal ME.
229  generated by topoisomerases are short-lived because of the religation activity of these enzymes, whi
230                 Their contribution is unique because of the scale and the diversity of care roles and
231  effects of contaminants remains challenging because of the sheer number of chemicals and their ambig
232                                              Because of the small number of results from well designe
233 hough the statistical power for this was low because of the small sample size.
234 arantine, and population-level interventions because of the specific transmission kinetics of this vi
235 lded polypeptides remains highly challenging because of the stringent requirement for simultaneous re
236 anically bound Fe dominates with this effect because of the strong dependency of iron oxyhydroxide so
237                                              Because of the transient subunit association, an atomic
238  owing to the difficulty in identifying them because of the typically long interval between carcinoge
239  passive, and heterogeneity may be increased because of the underlying pathophysiology leading to Fon
240                                              Because of the unique attributes of several of these new
241                                              Because of the unique role of the mouse as a genetically
242 simply infeasible for many taxa and settings because of the vast numbers of animals involved-hundreds
243 ce infection is established, and this may be because of the very early formation of a reservoir of la
244                                              Because of the vital role that these S proteins play, th
245 , supercoil dynamics are difficult to access because of the wide range of relevant length and timesca
246 istent organic pollutants of global interest because of their associations with adverse health outcom
247 ctating seals to display energy compensation because of their breeding strategy of high energy transf
248 of atmospheric chemistry, they were selected because of their broad relevance to other areas.
249 azardous substances to public health, mainly because of their carcinogenicity and oxidative potential
250 a spin splitting and anomalous Hall effects, because of their characteristic layered structures compo
251 ar polyatomic molecules has remained unknown because of their complex structure.
252 tructure of depressive symptoms in late-life because of their distinct etiologic factors, clinical pr
253                                              Because of their dual protease and ligase activity, plan
254 hingolipid metabolites have gained attention because of their essential role in the pathogenesis and
255 gnetic systems have been studied for decades because of their extraordinary properties and promising
256 porated into billions of commercial products because of their good colour saturation, versatile form
257 mental waters is an alarming issue, not only because of their harmful effects in the environment but
258 e promising as strategies for drug delivery, because of their high drug loading capacity and low prem
259                                              Because of their high level of diversity and complex evo
260 of major environmental and practical concern because of their highly toxic effects on human health an
261 AFMs) possess great potential in spintronics because of their immunity to external magnetic disturban
262  attracted enormous interest in recent years because of their implications in many areas of chemistry
263 airs have been challenging to directly probe because of their inherently fast timescales.
264 ignificant chemical and biological attention because of their intriguing carbogenic frameworks, react
265 dimers have attracted considerable attention because of their intriguing electronic features.
266  are high-interest targets in drug discovery because of their involvement in numerous biological proc
267 is of cycloarenes in solution is challenging because of their low solubility and the often hindered c
268 erests in bioaerosols have rapidly increased because of their many potential health effects.
269 ells (PVSCs) have drawn increasing attention because of their outstanding thermal stability.
270                                              Because of their prominent roles in development, cancer,
271 those that were partially buried, presumably because of their reduced access to water.
272                                              Because of their restricted cell type expression and rol
273  harmful effects in the environment but also because of their risk to human health.
274  has mainly focused on redox-active proteins because of their role in biological charge transport.
275 ections that defied direct visual resolution because of their size and rapid movement.
276 but recalcitrant to automated identification because of their size and sequence complexity.
277                                     However, because of their special physical characteristics, the f
278 ations are an interesting part of this group because of their tendency to undergo rearrangement, some
279                                              Because of their unique morphological and functional spe
280 es, NO, H(2)S, and CO occupy a special place because of their widely known physiological functions in
281 t adaptive behaviour in spite of, and indeed because of, their departure from veridical representatio
282                                              Because of these commonalities, one could propose that t
283                                              Because of these features, magnetosome magnetite crystal
284                                              Because of this asymmetry, the net-negative charge at th
285                                              Because of this difference, inhibitors of metastasis mus
286                                              Because of this movement, daughter cells may be born dis
287                                              Because of this success, the interest in integrating nan
288                                              Because of this, the droplet-mediated transport system i
289  of age, at which point she was hospitalized because of three syncopal episodes that were not related
290  that cell contacts are highly heterogeneous because of topography- and protein-density-related proce
291 ntly, skyrmions have high physical stability because of topological protection.
292 a (ALL) treatment, but is often discontinued because of toxicity.
293 l carbonyls that are challenging to quantify because of unavailability of standards.
294  the transcriptome remain unclear, primarily because of uncertainty over the mechanism that detects t
295 ined efforts to target those at highest risk because of underlying conditions with a range of prevent
296               Two participants were excluded because of unequivocal evidence of liver metastases at b
297 lectrochemical energy conversion and storage because of unique electronic and structural properties,
298               Thereby the risk for rejection because of unnecessary reduction of immunosuppression in
299  in realistic light intervals across a year, because of weather and seasons.
300 n survival compared with untreated controls, because of whole-body toxicity.

 
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