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1 Results suggest that the world became ~1.5% more suitable per decade for the developmen

2 responsive color change and shelter seeking, became a key species of interest [4, 8, 9].

3 treatment arms was enhanced and RNFLT change became a stronger predictor of VF progression.

4 uary onset of plant growth and the ecosystem became a sustained carbon sink well before winter ended,

5 emained significant and anti-IL-6 antibodies became a trend after controlling for physical response t

6 Biologic agents have become a core component of therapeutic strategies for ma

7 overlapping which may arise in such data and become a crucial aspect for determining classification p

8 Cancer biomarker research has become a data-intensive discipline requiring innovative

9 Childhood obesity has become a global pandemic in developed countries, leading

10 S-CoV-2), emerged in late 2019 and has since become a global pandemic.

11 antibiotic resistant pathogenic bacteria has become a global threat, which besides the development of

12 s-reactivity in ZIKV and DENV infections has become a great concern.

13 Psychology needs to become a historical science if it wants to be a genuinel

14 The anterior temporal lobes (ATL) have become a key brain region of interest in cognitive neuro

15 ATAC-seq has become a leading technology for probing the chromatin la

16 of their targets and are therefore poised to become a main pillar of cellular cancer immunotherapies.

17 f transcription factors using these data has become a major challenge in genomic research.

18 ic algae ("bleaching") under heat stress has become a major problem for reef-building corals worldwid

19 3D printing technology has become a mature manufacturing technique, widely used for

20 nonymous to synonymous mutations (dN/dS) has become a popular method to detect selection in somatic c

21 Ion mobility-mass spectrometry (IM-MS) has become a powerful tool for glycan structural characteriz

22 maging of fluorescent activity reporters has become a powerful tool for studying the function of the

23 Single cell sequencing has become a powerful tool to study the genome of individual

24 nges have to be overcome for this concept to become a practical way to encode and manipulate error-pr

25 Marchantia polymorpha has recently become a prime model for cellular, evo-devo, synthetic b

26 Chemical vapor deposition (CVD) has become a promising approach for the industrial productio

27 erefore, atezolizumab plus bevacizumab might become a promising treatment option for these patients.

28 The proposed assay may become a prototype for point-of-care diagnosis of drug r

29 tion (LKD), especially for young donors, has become a real matter of concern in the transplant commun

30 Food allergies have become a significant heath burden as prevalence continue

31 FOLFIRINOX has become a standard therapy for patients with advanced PDA

32 Selenium NMR has become a standard tool for scaling the pai-accepting cha

33 Thus, cardiac D1R has the potential to become a therapeutic target for preventing heart failure

34 recent emergence, and symptom screening has become a ubiquitous tool in the global response.

35 Our hope is that the TRPA1 KO rat will become a useful tool in further studies of TRPA1 as a dr

36 ment tools for RNA 3D structures, STAR3D has become a valuable tool for its unprecedented speed and a

37 ansoceanic movements that have enabled it to become a worldwide pest.

38 lammation that is not resolved in due course becomes a chronic disease.

39 abidopsis lnp1-1 lnp2-1 mutant cells, the ER becomes a dense tubular network.

40 R) RNA, such that the native GS conformation becomes a low-abundance ES.

41 ICL and related branched DNA structures, and becomes a sliding DNA clamp that can coordinate the subs

42 Although Abeta levels become abnormal long before severe cognitive impairments

43 lateral liquid, paracellular HCO(3) (-) flux becomes absorptive, tempering the alkaline pH generated

44 eptionally difficult to eradicate after they become abundant in their new habitats.

45 nt to exploit multiple data streams that are becoming abundantly available during the pandemic.

46 ata shows that regulatory elements gradually become accessible within pre-existing TADs during early

47 It becomes accessible upon pocket opening for selective cov

48 When dormant naive T cells first become activated by antigen-presenting cells, they expre

49 icularly under conditions when the epidermis becomes "activated" (hyperproliferative), remains unclea

50 important complication in pregnant women who become acutely infected with Brucella melitensis is spon

51 ion in African women, and pregnant women who become acutely infected with HIV account for up to a thi

52 A group of cells that can become adipocytes controls the formation of blood vessel

53 Residual Dipolar Couplings (RDCs) have become an alternate approach for structure calculation b

54 This study suggests that SNVs may become an important consideration in SARS-CoV-2 classifi

55 o improve recombinant protein production has become an important tool, but is still rarely applied to

56 ntimicrobial stewardship programs (ASPs) has become an increasing global focus.

57 Cardiovascular disease (CVD) has become an increasingly common limitation to effective an

58 e improve, and costs diminish, iEcology will become an increasingly important means to gain novel ins

59 des, X-ray absorption spectroscopy (XAS) has become an indispensable method for probing the structure

60 Genetic testing has become an integral component of the diagnostic evaluatio

61 ed into heat, and thus improved heat removal becomes an important factor in increasing performance.

62 Power analysis becomes an inevitable step in experimental design of cur

63 ges, in which the period of the limit cycles becomes an integer n > 1 multiple of the driving period.

64 Resourcing real-world evidence (RWE) is becoming an increasingly important asset in developing n

65 Nature-based solutions are becoming an increasingly important component of sustaina

66 gh CH(4) accumulation in oxic surface waters became apparent in recent years, the sources are still s

67 sociation between the two rhythms in V4 that became apparent when the major feedforward input to V4 w

68 It has recently become apparent that the diversity of microbial life ext

69 Yet, extreme wet episodes, which are becoming as severe and frequent as droughts, are overloo

70 that KEAP1 sheds many basal interactions and becomes associated with known lysosomal trafficking and

71 The DHHC enzyme then becomes autoacylated at a site defined by a conserved As

72 e took advantage of space and personnel that became available due to closure of the research division

73 of 6,228 and 38,248 SARS-CoV-2 genomes which became available later.

74 widely used in rheumatic diseases since they became available over 60 years ago.

75 ecently, plasma separation cards (PSCs) have become available and, though more expensive, have lower

76 istils the results of vaccine trials as they become available.

77 ions, until further direct experimental data become available.SIGNIFICANCE STATEMENT The hippocampal

78 more active and respire nitrate when oxygen becomes available at low concentrations suggests that th

79 rapy for Leber congenital amaurosis (LCA) is becoming available, and therefore it is crucial to ident

80 Despite multiple gene expression studies becoming available, the limited overlap of reported p63-

81 me into the limelight ten years ago, we have become aware that responses of holobionts to climate cha

82 from furnishings and building materials have become better regulated and energy efficient homes may r

83 transporter activity of class I proteins is becoming better understood, class III protein functions

84 pathogenesis by preventing macrophages from becoming both hemophagocytic and hyperactivated under pr

85 te 3 substitutions of W156A and L160E, which become buried at the complex interface, disrupt binding

86 er, with 11 000 annual publications this has become challenging.

87 sible interactions (covalent or noncovalent) becomes challenging, especially when the target is made

88 Furthermore, it has become clear that ARV therapy does not fully restore hea

89 ids and sphingolipid metabolites, and it has become clear that the intracellular sphingolipid composi

90 It now becomes clear that cell metabolism is an integral part o

91 It is becoming clear that alterations to HEV network density a

92 RNAs previously considered noncoding, it is becoming clear that these initial assumptions are incorr

93 These influences have become clearest in nanoscale experiments, in terms of st

94 s the fraction of atmospheric particles that become cloud droplets.

95 Multiyear stanzas above 2.1 degrees C become commonplace in projections from ~2030 onward, wit

96 en additionally monocyte-derived cells (MCs) become competent antigen-presenting cells (APCs).

97 Physicians need to become competent in understanding the potential risks an

98 CAR assembly in S. pombe when its integrity becomes compromised during cytoskeletal damage and stres

99 We found that antineoplastic drugs become concentrated in specific protein condensates in v

100 f the aromatic rings allows for the rings to become coplanar; this manifests in a more ribbon-like st

101 nation success at marginal temperatures will become critical for the long-term persistence of many pl

102 In hypoxia, however, glycolysis becomes critical for cytokine production and cell surviv

103 As the membrane becomes crowded by ENTH proteins, the polymer chain exte

104 hat phosphorylation of Thr(17) by CaMKII may become crucial for 14-3-3 recruitment to DeltaArg(14) PL

105 st-effective tools for viral load monitoring become crucial to allow specific diagnostics and the eff

106 fic and simple quantitation of microRNAs are becoming crucial enablers of early diagnosis and therape

107 ation levels prior to global de-methylation, become de-methylated during global de-methylation, and t

108 ing agent therapy is not effective generally become dependent on red-cell transfusions.

109 These Heinz bodies become deposited on the cell membranes and can lead to h

110 Context-drug associative memories become destabilized on retrieval and must be reconsolida

111 r combs(5,6), an injected monochromatic wave becomes destabilized by the interplay between the resona

112 Our results show that membrane necks become diffusion barriers.

113 er <-> dimer <-> tetramer <-> hexamer, which becomes directional toward the large oligomeric states w

114 antly, membrane morphology and lipid packing became disrupted.

115 s a result, interactions between species can become disrupted, with potentially detrimental effects.

116 ination of a specific virus (H1delta-2) that becomes dominant among exhibition swine and is associate

117 r ratio on both sides decreased as the ankle became dorsiflexed, but the slope of the fascicle gear r

118 us signaling pathways, have the potential to become drug candidates for distinct central nervous syst

119 teractions change when the endothelial cells become dysfunctional and have an impact in diseases such

120 est that MAIT cells are highly activated and become dysfunctional during clinical sepsis, and contrib

121 suggest that reward provided during training becomes effective during sleep, with excited reward proc

122 offer varied and remarkable functionalities, becoming efficient building blocks for the construction

123 nclusion: ITPR3 expression in cholangiocytes becomes enhanced in CCA.

124 ernative explanation is that multimers could become entrenched if substitutions accumulate that are n

125 sed by an unknown spectrum of prions and has become enzootic in populations of cervid species that ex

126 navirus 2 (SARS-CoV-2) transmission networks became established in Europe and North America.

127 uld have prevented SARS-CoV-2 outbreaks from becoming established in these regions.

128 in treatment decisions, this knowledge will become ever more important to optimize our patients' car

129 ally recruits neighboring pericycle cells to become FCs.

130 r sequence of the mammalian POLG gene, which became fixed in placental mammals.

131 s dynamic in isotropically growing cells but becomes fixed in anisotropic cells and aligns with the a

132 system consists of GFP-based reporters that become fluorescent upon cleavage by recombinant DENV-2/Z

133 The rate of resistance decay to become fully susceptible from moderate-intensity resista

134 nvironment on the epithelial boundary, which becomes further dysbiotic by the synergistic action of b

135 perfectly alternating 3' U and G nucleotides become gene-silencing agents.

136 ion occurs along the sides of fibrils, which become heavily decorated under the current solution cond

137 e for generating glucosylceramide, colonoids become highly permeable, lose structural integrity, and

138 my between bivalent genes that do and do not become hypermethylated, which is also mirrored in cancer

139 let therapy for existing conditions prior to becoming ill with COVID-19 have different outcomes from

140 f an inhibitory morphogen, but how this cell becomes immune to self-inhibition is rather unknown.

141 However, HA antigenic site B, which has become immunodominant in recent human H3N2 influenza vir

142 such lines have existed for decades and has become important research tools in genome studies as wel

143 of MMP-selective agents; accordingly, it has become important to identify a platform with which high

144 difficult and lacks long-term stability, it becomes important to unravel the etiology of LF pattern

145 ch do not produce adhesive FLO1, nonetheless become incorporated into flocs at a higher frequency tha

146 and diversified in benthic environments that became increasingly available as ice retreated.

147 al activity that discriminated between tones became increasingly stable in time as the information co

148 assive recorders of ocean conditions, it has become increasingly clear that biological processes play

149 However, as niches become increasingly filled, diversity hits a plateau (as

150 x cardiovascular needs of these patients has become increasingly important, resulting in an imperativ

151 VLNT and LVB have become increasingly popular in the treatment of lymphede

152 e spread is difficult to predict, but should become increasingly predictable over multiple fire cycle

153 P-Rex1 has also become increasingly recognized for its role in promoting

154 are markedly weak in 1-cell SCNT embryos and become increasingly strengthened afterward.

155 hms to convert spoken language to text, have become increasingly widespread, powering popular virtual

156 the most informative and discriminative ones becomes increasingly important.

157 nide as the identical isotopic mass disorder becomes increasingly invisible to phonons.

158 ity of interbacterial antagonism pathways is becoming increasingly apparent, and the insidious manner

159 Large-scale energy storage is becoming increasingly critical to balancing renewable en

160 corporating optical cavities in ion traps is becoming increasingly important in the development of ph

161 itive markers of Alzheimer's disease (AD) is becoming increasingly important.

162 oaches to modeling of epidemiologic data are becoming increasingly more prevalent in the literature.

163 Marijuana is becoming increasingly potent, and smoking marijuana carr

164 sms supporting human-machine interactions is becoming increasingly pressing.

165 taff testing may help prevent hospitals from becoming independent 'hubs' of SARS-CoV-2 transmission,

166 f gas formation or during reservoir storage, becoming indistinguishable from equilibrium in the most

167 correlate with viral loads in recipients who became infected, cross-reactivity did appear to influenc

168 al virus (RSV) to 58 volunteers, of whom 57% became infected.

169 c Islands, and parts of South America, often become infected at birth and account for up to 95% of ne

170 out COVID-19, to not believe that they would become infected, and to feel less prepared for an outbre

171 ing as to how these groups will fare if they become infected.

172 The EHR has become integral to perioperative care.

173 sociates from extracellular matrix proteins, becoming internalized with CD63, which is necessary for

174 nical work and the processing of information become intertwined at the molecular scale, creating a fa

175 attern categories generated by AW-Fisher can become intractable.

176 s of the particles, an entire experiment can become irreproducible.

177 Hepatitis B and C virus-associated HCC became less common, and more patients were diagnosed at

178 residues near predicted hairpin hinges that become less constrained in the LD environment.

179 oduction will be reduced because masting has become less effective at satiating seed predators.

180 In contrast to neurons, astrocytes become less synchronized during non-rapid eye movement s

181 ion of premalignant to malignant disease and becomes less prevalent after therapy, in which it is ass

182 he presence of substrates, with the majority becoming less accessible in the presence of saturating c

183 nse mechanisms acting when other amino acids become limiting, we tested the efficacy of prokaryote-sp

184 Control cells became lodged in the first capillary bed encountered in

185 neuronal firing rates increase and waveforms become longer in duration and shorter in amplitude as th

186 In honeybees, learning flights become longer when the reward offered by a flower is inc

187 nce favoured in an ancient environment might become maladaptive upon environmental changes.

188 nt surgeon, psychologist and psychiatrist is becoming mandatory to properly evaluate the candidate to

189 tissue being tested and for phenotypes that become manifest in older ages.

190 gnate Ag at a defined effector checkpoint to become memory cells.

191 sized proteins and refolding those that have become misfolded in the context of a crowded cytosol.

192 s, the mechanism by which the cancer nucleus becomes misshapen is not fully understood.

193 number of animal species lend themselves to becoming model organisms in multiple biological discipli

194 Cisterns became more prevalent over the course of the first 20 ye

195 We find that snow droughts became more prevalent, intensified, and lengthened acros

196 d oligodendrocyte lineage cells subsequently became more responsive.

197 c abundances in freshwater environments have become more common in the past five years, but few studi

198 obesity, diabetes mellitus and hypertension become more common in the pregnant population.

199 s evolution and the reactions catalyzed have become more complex with time.

200 ry and empirical work suggests that song may become more elaborate with age, there are a paucity of l

201 ture, as other renewable electricity sources become more important, electricity production from bioma

202 tly, the relevance of non-HLA antibodies has become more prominent as AMR can be diagnosed in the abs

203 ation loop with out-of-plane magnetic fields become more prominent.

204 ) this adaptation increases as water sources become more rare.

205 hanges induced with omalizumab treatment and become more similar to the control subjects, while non-r

206 As biosimilars become more widely available in oncology, especially wit

207 the lysis is delayed until host/phage ratio becomes more favorable for the release of progeny.

208 that the ligand shell of Au(25) nanoclusters becomes more fragile and rigid after ligand addition.

209 We reveal that the SARS-CoV-2 virus becomes more infectious.

210 Our findings suggest that as the environment becomes more severe [1], the resilience of some species

211 As segment 2 interacts with AbpSH3, it becomes more structured, but retains flexibility even in

212 ntestinalis, and potentially gas gangrene is becoming more common and was utilized effectively in thi

213 st at the cave site was absent at that time, becoming more frequent from about 1.35 Ma, as the Northe

214 ave further adapted to gallinaceous poultry, becoming more highly transmissible and causing higher mo

215 led worldwide since 1975 as environments are becoming more obesogenic.

216 l symbiont community can lead to some corals becoming more or less thermally tolerant.

217 to a pattern of "seasonally variable regimes becoming more variable".

218 functions that are trivial on linear genomes become much more difficult in genome graphs.

219 4AD co-assembly, the light-harvesting system becomes near-infrared (NIR) emissive (675 nm).

220 er cells progressively lost centrioles after becoming near-tetraploid, we transiently transfected dip

221 at hour 6, risk was reduced for patients who became negative (23.8% vs 9.8%, p=0.01; OR 2.15, 95%CI 1

222 emerges in the quiescent state, and the flow becomes nonlinear.

223 lated to interactions with nanomaterials has become of interest due to its therapeutic potential.

224 Programmed cell death protein 1 (PD-1) has become one of the most investigated targets for cancer i

225 3D printing has become one of the most promising methods to construct de

226 y for the presence of mosquitoes and viruses becomes one of the most important pieces of information

227 individuals with the skills and knowledge to become outstanding scientists and expand knowledge throu

228 Importantly, this system can become overloaded due to ongoing environmental demands o

229 high, high-grade serous ovarian cancer cells become PARPi sensitive, undergo mitotic catastrophe, and

230 nano-oscillators, the frequency spectrum can become particularly complex.

231 olonizes human mucosal tissues and skin, can become pathogenic, clinically manifesting most commonly

232 underwent enucleation at 6 months, and 1 eye became phthisical 1 year after endophthalmitis.

233 hosts to a lethal lytic stage as host cells become physiologically stressed.

234 cholangiocytes in the channel of the device became polarized and formed mature tight junctions, that

235 ive [TIMP-2]*[IGFBP7] at baseline, those who became positive (>0.3 units) after resuscitation had 3-t

236 tion and detection of this high-momenta mode become possible with our resonator design that can boost

237 Here, we show that this differentiation becomes possible by adding the local environmental infor

238 At atomic resolution, it becomes possible to extend frustration analysis to prote

239 As our science progresses, it is becoming possible to apply the principles of population

240 Nucleic acid nanoparticles (NANPs) have become powerful new platforms as therapeutic and diagnos

241 Yet they become practically unusable upon cutting much softer mat

242 e management in women who might subsequently become pregnant.

243 ection who are now ageing into adulthood and becoming pregnant.

244 0.2 M NaCl), we find that plectoneme pinning becomes probabilistic and the pinning probability increa

245 eliably responsive to any of the stimuli and becomes progressively larger in higher visual areas.

246 ing it to undergo conformational changes and become prone to proteolytic activation.

247 l TPLSM, the fluorescence signal of a vessel becomes proportional to its size, which enables convenie

248 were not more frequent in subjects who later became psychotic than those who did not.

249 important opportunistic pathogens which have become public health priorities linked to major hospital

250 arkable plasticity during development before becoming quiescent and functionally mature.

251 Plastics become rapidly colonized by microbes when released into

252 lated during global de-methylation, and then become re-methylated.

253 capture <1% of HH opportunities and rapidly become recognized by staff, resulting in inflation in pe

254 n stem cell-specific accessible regions that become repressed in endoderm.

255 Metastatic tumors that have become resistant to androgen deprivation therapy represe

256 The PVCs become resistant to inhibition and have an increased cap

257 Mutations that allow tumors to evolve and become resistant to treatment can be readily identified

258 1), which continues to increase as the cells become resistant with a mesenchymal phenotype.

259 ing resolution and cell-specific annotations become richer.

260 Our discovery that podocytes become sensitized to AngII-induced calcium signaling upo

261 However, at oxidation state IV, complex 2(+) becomes seven coordinated with the two phosphonic groups

262 s, for reasons we do not understand, malaria becomes severe and life threatening.

263 Visual models became significant early after image onset, and identity

264 We find that TADs are lost as genes become silenced on the paternal X chromosome but linger

265 at when stone tip cross-sectional geometries become smaller over time in particular contexts, this ev

266 mum free energy path between the CIP and SIP becomes smoother at high pressure, and the relative stab

267 muscles contract, myosin-containing A-bands become split and adjacent myosin filaments move in oppos

268 ve approach against myosin V, spine synapses became stronger compared to controls.

269 of exposure to the alkaloids, the parasites became swollen and rounded in shape, with hypertrophied

270 COPI vesicles likely become tethered while they bud, thereby promoting effici

271 vulnerable communities fearful that they may become the center of next ZIKV outbreak.

272 China was forecasted to become the largest economy by 2035 but in the reference

273 enario, the USA was forecasted to once again become the largest economy in 2098.

274 untries, mortality from cancer will probably become the leading cause of death.

275 MtSSPdb also has the potential to become the most complete database of SSPs in plants.

276 In the past 20 years, MRI has become the most useful paraclinical tool in both situati

277 actin in 1981, the pyrene-labeled actin has become the most widely employed tool to measure the kine

278 f microbial nucleic acids in body fluids has become the preferred method for rapid diagnosis of many

279 racic endovascular aortic repair (TEVAR) has become the primary surgical treatment modality for desce

280 With about 800 curated models, BioModels has become the world's largest repository of curated models

281 d regulates erythrocyte maturation, where it becomes the most abundant miRNA.

282 rane antigen (PSMA)-targeting PET imaging is becoming the reference standard for prostate cancer stag

283 mCG becomes transiently asymmetric during S phase but is rap

284 anded ballistically outward, while the other became trapped at the substrate.

285 promising but niche treatment, has suddenly become treatment as usual.

286 Interestingly, the emission of GO-AuNPs becomes "turn-on" after the addition of 75 x 10(-6) M KM

287 nd two centrosomes in animal cells naturally become two spindle poles.

288 earning networks to real-world problems have become ubiquitous, our understanding of why they are so

289 As OCT becomes ubiquitous, OCT-derived measurements may provide

290 t rate in a novelty-free manner, have merely become undetectable by search algorithms used to infer h

291 flagging and delabelling virus lineages that become unobserved and hence are probably inactive.

292 ts responded to a target stimulus until they became unresponsive.

293 a green fluorescence protein (GFP) reporter becomes unstable when fused to the last 10 amino acids o

294 720 nm, the next generation of miRFPs should become versatile NIR probes for multiplexed imaging acro

295 Cancer cells then become very dependent on the proper function of those pa

296 understanding of these secondary effects is becoming vital now that FUS-BBB opening treatments have

297 genomic instability, when the entire genome becomes vulnerable and multiple chromosomal alterations

298 The cell aggregates-spheroids-have become widely used model objects in the study of this ph

299 Droplet-based microfluidic devices have become widely used to perform single-cell RNA sequencing

300 ghbors, while its overlying epithelial cells become WNT-restricted.