ライフサイエンスコーパス: bedside

1 third alternative of 'handover away from the bedside'.

2 al movement of information between bench and bedside.

3 g clues for ways to connect the bench to the bedside.

4 utaminase diseases: from biochemistry to the bedside.

5 enable rapid phenotype identification at the bedside.

6 uration for transporting cells from bench-to-bedside.

7 engaged as partners with the ICU team at the bedside.

8 the laboratory into improved outcomes at the bedside.

9 al risk" noted in outcomes trials and at the bedside.

10 application of this technology from bench to bedside.

11 ts use, as they evolve from the bench to the bedside.

12 between theory and practice at the patient's bedside.

13 s may decrease time and effort from bench to bedside.

14 not worked itself to the clinical thrombosis bedside.

15 neous blinded clinical UAO assessment at the bedside.

16 o translate disease treatments from bench to bedside.

17 ocusing on transitions between the bench and bedside.

18 for rapid point-of-care detection of PMPs at bedside.

19 ndidate therapeutics has moved from bench to bedside.

20 e used right by the critically ill patients' bedside.

21 peed with which these can move from bench to bedside.

22 mon, pragmatic approach by physicians at the bedside.

23 allowed moving this biomarker from bench to bedside.

24 lity of using wave intensity analysis by the bedside.

25 ) have been translated from the bench to the bedside.

26 cal information that is readily available at bedside.

27 on systems, and return those findings to the bedside.

28 monitoring technology from the bench to the bedside.

29 ocardiography, which can be performed at the bedside.

30 s generally preferred handover away from the bedside.

31 patients (44.4%) had a family member at the bedside.

32 ting to translate cellular mechanisms to the bedside.

33 clinical management of sepsis at the patient bedside.

34 (SERM) that could move quickly from bench to bedside.

35 cal coherence tomography (OCT) system at the bedside.

36 erial elastance may be reliably estimated at bedside (0.9 x systolic femoral pressure/stroke volume).

37 ata consisted of observations of patients at bedside (170h in total); observations of the context of

38 in 94%, and 23 (6.6%) were leukoreduced (10 bedside, 2 prestorage, and 11 unknown).

39 amily members were absent from the patient's bedside (6.3 minutes [95% CI, 2.2-10.4] vs 11.7 minutes

40 nce, a novel measure readily attainable from bedside accelerometry.

41 lbourne Rapid Field, (MRF)) conducted at the bedside aided swift and appropriate management of the pa

42 eferred handover to take place away from the bedside, all else equal.

43 ers are beginning to translate from bench to bedside along the paths of neuroprotection, gene replace

44 whole translational spectrum (from 'bench to bedside and back again') with recognition that both biol

45 f cerebral blood flow (CBFi) at the infant's bedside and compute an index of cerebral oxygen metaboli

46 vasive diagnostic instrumentation, with both bedside and intra-operative operation capability, is env

47 rfusion map characterization as inexpensive, bedside and longitudinal indicator of tumor perfusion fo

48 isdictional guidance, capacity and safety of bedside and research personnel, disposition of patients

49 eral aspects of the research process such as bedside and research staff safety, infection control, th

50 ion of lung aeration can be performed at the bedside and used in mechanically ventilated patients to

51 judgment skill they bring to their patients' bedsides and to the array of evidence presented to them

52 available to assess respiratory drive at the bedside, and discuss the implications of altered respira

53 Through an iterative bench-to-bedside-and-back process, methods to efficiently add new

54 , some of which are already practiced at the bedside; and the challenges of implementing molecular pa

55 nd how our therapies work and to improve the bedside applicability of RCTs.

56 godendrocyte biology and neuroradiology with bedside applications may result in the possibility of cl

57 We propose a bedside approach to estimate recruitability accounting f

58 in the determination of tissue perfusion and bedside approaches to management of shock.

59 ers exist for either, which impedes bench-to-bedside approaches.

60 tween DNIC and CPM, gauged between bench and bedside, are key for the development of analgesic therap

61 yses revealed the desire to be at the baby's bedside as a driver of maternal health-seeking behaviors

62 ses requiring complex decision making at the bedside as to when prompt antibiotics are indicated and

63 ipate that PulseCam will be used both at the bedside as well as a point-of-care blood perfusion imagi

64 the trajectory of a biomarker from bench to bedside as well as the regulatory and other requirements

65 some of the disparity between the bench and bedside, as well as emerging avenues for combining the c

66 t percent of eyes (n = 53) underwent initial bedside aspirate with intravitreal injection of antibiot

67 This study also reports that a simple bedside assessment for the presence and intensity of pai

68 ma Scale has provided a practical method for bedside assessment of impairment of conscious level, the

69 Physician bedside assessment of sonified electroencephalography (3

70 olism showed no significant association with bedside behavioral testing, except in a few cases when E

71 Recent researches for bedside biosensors are also discussed.

72 s shows potential for realising miniaturised bedside biosensors for clinical diagnostics exploiting M

73 ion in critical care-not just as part of the bedside, but as part of educational and management organ

74 ique is radiation free and applicable at the bedside, but lacks of spatial resolution compared to mor

75 Noninvasive near-infrared spectroscopy-based bedside calculation of optimal mean arterial blood press

76 measured physiologic variables using simple bedside calculations (functional hemodynamic monitoring)

77 commendations were made regarding the use of bedside cardiac ultrasound in pediatric patients ranging

78 veral class 1 recommendations for the use of bedside cardiac ultrasound, echocardiography, in the ICU

79 the unit level where nurses provide 24-hour bedside care to patients.

80 red nurses need to assume responsibility for bedside care.

81 ally triggered further patient resistance to bedside care.

82 ir stay were more likely to be observed in a bedside chair and less likely to be observed in bed, as

83 zed to the control group (n = 164) underwent bedside chest tube insertion with local anesthesia follo

84 ggest that PVP may be useful in the standard bedside clinical assessment of volume status in these pa

85 h the remote evaluation of fundus images and bedside clinical examination of infants at risk for ROP.

86 ical criteria that together constitute a new bedside clinical score termed quickSOFA (qSOFA): respira

87 s and is now enjoying unprecedented bench-to-bedside clinical success.

88 new standardized handoff protocol requiring bedside clinician communication using an information tem

89 gation of information can be used to aid the bedside clinician in this task: analysis of derived para

90 In the second phase, bedside clinicians were additionally assisted in guideli

91 This concise review aims to provide bedside clinicians with ways to think about common metho

92 ies, and, in most cases, will not be made by bedside clinicians.

93 behavioural evidence of consciousness at the bedside, clinicians may render an inaccurate prognosis,

94 Care Delirium Screening Checklist, a focused bedside cognitive examination, chart review, and nurse i

95 ales, physical and neurological examination, bedside cognitive tests, neuropsychological assessment,

96 resent a comprehensive pipeline for reliable bedside collection, sequencing, and analysis of the huma

97 owed a strong preference for handover at the bedside compared to nurses.

98 Bedside confirmation of bundle checklists during physici

99 the auditory startle reflex (hASR) tested at bedside constitutes a novel, simple and powerful behavio

100 POTTER could prove useful for bedside counseling and for benchmarking of ES care.

101 ome a prototype for transition from bench to bedside, culminating in the development and clinical imp

102 gap exists in translating this knowledge to bedside decision making.

103 n time to admission was 2 h (IQR 1-3) with a bedside decision to admit, and 12 h otherwise (5-29).

104 Early bedside detection of intraventricular hemorrhage holds p

105 Early bedside detection of intraventricular hemorrhage is cruc

106 nsitive, and specific tool, which allows for bedside detections of the morphologic patterns in acute

107 of-care testing field: easy miniaturization (bedside devices) and low cost.

108 nd pulmonary gangrene and to assess how this bedside diagnosis could impact the prognosis of the dise

109 sults of different omics approaches for both bedside diagnosis of immune dysfunction and detection of

110 Bedside diagnosis of sarcopenia by ultrasound predicts a

111 ful biological surface functionalization for bedside diagnostic assays.

112 nstrates that fingerstick CRAG is a reliable bedside diagnostic test.

113 s in Africa, demands immediate attention for bedside diagnostics.

114 Bedside DOSI images of the tissue concentrations of deox

115 When comparing percutaneous bedside drainage to operating room burr hole evacuation,

116 he exposures were time from (1) admission to bedside dysphagia screen, and (2) admission to comprehen

117 We aimed to identify if delays in bedside dysphagia screening and comprehensive dysphagia

118 licity of use, availability at the patient's bedside, easy transportability, and relatively low cost

119 After a rapid bedside echocardiogram suggesting pulmonary embolus, thr

120 As bedside echocardiographic technology becomes more rapidl

121 Bedside echocardiography enabled confirmation of these r

122 Physicians can be taught bedside echocardiography in a time-effective manner with

123 se patients after cardiac arrest and enables bedside EEG interpretation of unexperienced readers.

124 ria can inform large-scale collaborative and bedside efforts to reduce inappropriate urinary catheter

125 Bedside electroencephalographic methods may corroborate

126 importance of conducting rounds at patients' bedside; essential participants in rounds; the inclusion

127 First, to validate bedside estimates of effective arterial elastance = end-

128 This study highlights a simple bedside evaluation of itch and pain for suspicious skin

129 Clinical bedside evaluations and right heart hemodynamic assessme

130 quality care and to detect infants requiring bedside examination.

131 r with documentation of volume "overload" by bedside examination.

132 lity were collected prospectively by trained bedside extracorporeal membrane oxygenation specialists

133 are (POC), such as at primary clinics or the bedside, faces impediments because they may require high

134 tion on variable cutoffs of gait response to bedside fluid-drainage testing.

135 understood to have evolved from the bench-to-bedside framework by which basic science transitions to

136 elin or peptide YY plasma concentration with bedside functional assessment of gastric emptying.

137 sound, a method increasingly considered as a bedside gold standard in critically ill patients due to

138 Bedside handheld spectral-domain optical coherence tomog

139 de repeated choices between two hypothetical bedside handover alternatives and a third alternative of

140 ient participation in nursing shift-to-shift bedside handover can be enacted.

141 When implementing bedside handover in a Swedish context this must be consi

142 nces could jeopardize future introduction of bedside handover in Swedish health care, and might expla

143 ed, we discovered that the patient's role in bedside handover involves contributing clinical informat

144 Shift-to-shift bedside handover is advocated as a patient-centred appro

145 n Swedish health care, and might explain why bedside handover is still not very common in hospital wa

146 although participation is a prerequisite for bedside handover.

147 arriers to enacting patient participation in bedside handover; and involving patients in beside hando

148 barrier to enacting patient participation in bedside handover; and involving patients in beside hando

149 (Informatics for Integrating Biology and the Bedside) has developed a widely internationally adopted

150 These subphenotypes could play a role in the bedside identification of cytokine profiles in patients

151 iation-free functional modality that enables bedside imaging and monitoring of lung function and expa

152 ising, inexpensive, radiation-free, tool for bedside imaging.

153 cal practice suggests that clinicians at the bedside implement measure to attenuate the risk of unint

154 se electroencephalography information at the bedside improved the sensitivity (95% CI) of physicians'

155 networks (CNNs) to predict diagnosis at the bedside in near real-time in an automated fashion.

156 e in detecting cerebral hypoperfusion at the bedside in patients with severe traumatic brain injury a

157 If deployed at the bedside in the clinical context, such network measuremen

158 rformance of stellate ganglion blocks at the bedside in the ICU is feasible for patients who are suff

159 al stellate ganglion blocks at the patient's bedside in the ICU.

160 All cannulations were performed at the bedside in the intensive care unit in patients who had u

161 At the bedside in the last 5 years, uric acid and nerinetide ar

162 idge the translational gap between bench and bedside in the near future.

163 ment programs, bringing teaching back to the bedside, increasing resident autonomy, utilizing near-pe

164 for the use of ventilatory ratio as a simple bedside index of impaired ventilation in ARDS.

165 The ventilatory ratio is a simple bedside index that can be calculated using routinely mea

166 s the potential for objective and real time, bedside insight in the neurologic prognosis of comatose

167 nd he was stabilized after cardioversion and bedside intubation.

168 Translation of novel therapies from bench to bedside is hampered by profound disparities between anim

169 ation from cellular and animal models to the bedside is hampered by significant differences between s

170 c studies, and their translation back to the bedside, is expected to eventually lead to improvements

171 d space fraction is easy to calculate at the bedside, it may be useful for risk stratification and se

172 In this article, we review the bench-to-bedside journey of natalizumab, along with the lessons l

173 ry mechanics in acute neurologic conditions, bedside judgment, interpretation of additional laborator

174 In Bench to Bedside, Kornelia Polyak peruses studies that uncover sp

175 mational in accelerating ideas from bench to bedside, maximizing scientific discovery and improving p

176 ering the patients' respiratory drive at the bedside may improve clinical assessment and management o

177 burdens required to bring lactoferrin to the bedside may limit its availability.

178 ng the first postnatal days is possible from bedside measures of brain activity prior to ultrasound c

179 specific detection of microRNA panels on the bedside, medical point-of-care systems that measure thos

180 ine connections to other PID caregivers, and bedside mental health services.

181 We aimed to determine which bedside method would provide positive end-expiratory pre

182 ar collapse and overdistension, but reliable bedside methods to quantify them are lacking.

183 Here, we describe a bedside microdialysis monitoring technique for optimizin

184 omated hematology analyzers, microscopy, and bedside microfluidic devices provide clinically feasible

185 prescription and modifiable practices at the bedside might enhance enteral protein delivery in the PI

186 Bedside monitor alarms alert nurses to life-threatening

187 The lack of bedside monitoring devices for alpha-amylase detection h

188 ons of a novel imaging approach that enables bedside monitoring of amygdala activity using fMRI-inspi

189 this method has been driven by the need for bedside monitoring of the dynamics of the lungs and the

190 This approach may assist in bedside monitoring of therapy or in improving the effica

191 rocardiography waveform time series from the bedside monitors of 9,232 ICU admissions.

192 l mean arterial blood pressure calculated by bedside multimodal cerebral autoregulation monitoring us

193 toregulation was determined using continuous bedside near-infrared spectroscopy and acquired brain in

194 ocSSRT is an easily-administered bedside neuro-physiological tool; significantly prolonge

195 science every day, the principles from which bedside neurology is derived have broader consequences-f

196 of new liposomal nanomedicines from bench to bedside, new cost-effective and scalable production meth

197 Bedside noncontact SD-OCT imaging was performed after ob

198 nell Assessment of Pediatric Delirium by the bedside nurse.

199 sleeping hours at night was assessed by the bedside nurse.

200 Bedside nurses also recorded the total time and number o

201 lgesia quality, but inconsistent adoption by bedside nurses limited its impact.

202 These patients' attending physicians and bedside nurses were also enrolled.

203 ents involved surrogates, awake patients, or bedside nurses, respectively.

204 hat Virtual ACE was extremely empowering for bedside nurses.

205 understood and thought to lack relevance to bedside nursing practice.

206 Bedside nursing staff administered dexmedetomidine (or p

207 We recorded 24 h EEG at the bedside of 18 patients diagnosed to be vigilant but unaw

208 We measured point-of-care CSF lactate at the bedside of 319 HIV-infected Ugandan adults at diagnosis

209 required to bring precision medicine to the bedside of critically ill patients with sepsis.

210 To view this Bench to Bedside, open or download the PDF.

211 ations revealed inconsistent disinfection of bedside ophthalmologic equipment and limited glove use.

212 and ocular surface disease were assessed on bedside ophthalmologic examination.

213 HIV or other health-threatening pathogens at bedside or in resource-limited settings.

214 diating nature of laser-based techniques for bedside or intraoperative microcirculatory perfusion ass

215 We compared our bedside paediatric early warning (PEW) score and a machi

216 ructure that underlies the original bench-to-bedside paradigm.

217 he delivery of actionable information to the bedside, particularly in the outpatient setting.

218 icroscopy has the potential to provide rapid bedside pathologic analysis, but clinical adoption has b

219 ration with a dedicated ID team performing a bedside patient evaluation within 1 hour of ED arrival.

220 nation could improve the diagnostic yield of bedside patient evaluation.

221 citly did not seek to include discussions of bedside patient-family engagement or shared decision-mak

222 Bedside physicians have to make most diagnostic and trea

223 rformed multivariate statistical analyses of bedside physiologic monitoring data to identify such ear

224 eclinical testing for FXS; however, bench-to-bedside plans for the clinic are severely limited due to

225 In less than 2 h, the PepS device allows bedside plasma separation from whole blood, volume meter

226 e iatrogenic pneumothoraces while performing bedside pleural procedures has increased but with little

227 ous after acute changes in blood flow, (2) a bedside point-of-care assay (platelet function analyzer-

228 nd 50 term infants with adequate images from bedside portable, handheld spectral-domain optical coher

229 Bedside positive end-expiratory pressure selection metho

230 and to promote its translation into clinical bedside practice for stroke management.

231 y because staff did not think it relevant to bedside practice.

232 totype for bedside to bench, and back to the bedside, practice of evidence-based precision medicine.

233 We developed a bedside predictive score for enterococcal IE-Number of p

234 ardized inspiration is a simple, noninvasive bedside predictor of fluid responsiveness in nonintubate

235 difficulty of obtaining thrombolytics at the bedside rapidly enough to administer during a code, and

236 ses and patients' personal caregivers at the bedside reported on their perception of patients' sympto

237 is typically used to refer both to "bench to bedside" research, in which preclinical research finding

238 rs of this new drug class provide a bench-to-bedside review on preclinical validation of IDO1 as a ca

239 multivariable results, a reliable and simple bedside risk prediction tool was developed.

240 cumented, elements were verified by provider bedside rounds.

241 biomedical studies and increase the bench-to-bedside safety and success of immunological studies.

242 tration rate (e-GFR) was estimated using the Bedside Schwartz equation, whereas 24-hour proteinuria w

243 Bedside screening for dysphagia was performed within 3 h

244 treated with intravitreal bevacizumab using bedside sedation returned to their preprocedure respirat

245 Bedside "sitters" are often used for patients at high ri

246 eferred technique for assessing ischaemia in bedside situations, whereas CT has the greatest value fo

247 , we discuss how the tried and true bench-to-bedside strategies resulted in some spectacular successe

248 ormed in 88% of patients and mostly portable/bedside studies, with 87% of patients receiving chest ra

249 ctors to AF pathogenesis from both bench and bedside studies.

250 lth and disease, exemplified by the bench-to-bedside success of Jak inhibitors ('jakinibs') and pathw

251 screening triggered confirmatory specialist bedside swallowing examinations and follow-up until hosp

252 Lung ultrasonography (LUS) is a bedside technique useful to diagnose neonatal respirator

253 xygenation quantified by a simple, sensitive bedside test.

254 , neurologic examination, neuropsychological bedside testing, and socioemotional assessments.

255 Simple bedside tests and somatosensory-evoked potentials predic

256 Although a variety of bedside tests are available, there is no agreement as to

257 duplex scan; PAD-scan) against commonly used bedside tests for the detection of peripheral arterial d

258 optimization of cardiac output is a feasible bedside therapeutic option, which should be considered w

259 ailures to translate research from "bench to bedside." These challenges emerge on a background of inc

260 e group randomized to presence or absence at bedside throughout the brain death evaluation with a tra

261 knowledge translation, moving away from the bedside to a focus on health systems, whereas translatio

262 These data might support the idea of a 'bedside to bench' concept, whereby results from clinical

263 , the PTEN-opathies serve as a prototype for bedside to bench, and back to the bedside, practice of e

264 , no calibration, and can be repeated at the bedside to generate almost continuous analysis of left v

265 s are beginning to be translated back to the bedside to improve treatment.

266 is expanding from real-time diagnosis at the bedside to include a capture, store, and forward model w

267 -care ultrasound is increasingly used at the bedside to integrate the clinical assessment of the crit

268 hat clinicians could easily calculate at the bedside to predict the risk of death of acute respirator

269 eed in rapid testing of visual fields at the bedside to screen for post-operative complications, such

270 Our in-depth bedside-to-bench analysis uncovers the molecular mechani

271 ction.SIGNIFICANCE STATEMENT We have used a "bedside-to-bench" approach to investigate the functional

272 ential role as a non-invasive and affordable bedside tool for predicting brain pathology and death in

273 mate P0.1ref.Conclusions: P0.1 is a reliable bedside tool to assess respiratory drive and detect pote

274 EIT may be an interesting noninvasive bedside tool to provide real-time monitoring of the PEEP

275 over the years, involving both non-invasive bedside tools (clinical decision rules and D-dimer blood

276 Bedside tracheostomy in COVID-19 does not cause addition

277 icroemboli burden, assessed noninvasively by bedside transcranial Doppler ultrasonography, correlates

278 Successful bench-to-bedside translation of nanomedicine relies heavily on th

279 o disease pathogenesis and expedite bench-to-bedside translation of new therapeutics.

280 tients and a substantial failure in bench to bedside translation of other potential therapies, the un

281 Challenges exist in bench-to-bedside translation, but they are not insurmountable.

282 epresents a promising candidate for bench-to-bedside translation.

283 rder that have been developed via a bench to bedside translational model.

284 An interdisciplinary, bench to bedside translational research approach is crucial for t

285 ultimately use our benchside data to improve bedside treatment.

286 Percutaneous bedside twist-drill drainage is a relatively safe and ef

287 hy, investigation of portal venous gas using bedside ultrasonography may help the clinician to identi

288 tracts describing the diagnostic accuracy of bedside ultrasound compared with chest radiography for c

289 ater reliability, and efficiency to complete bedside ultrasound confirmation of central venous cathet

290 and meta-analysis to examine the accuracy of bedside ultrasound for confirmation of central venous ca

291 Bedside ultrasound is faster than radiography at identif

292 Bedside ultrasound reduced mean central venous catheter

293 Awareness of the impact of bedside ultrasound to reduce iatrogenic pneumothoraces w

294 central venous catheter malposition exists, bedside ultrasound will identify four out of every five

295 acidic protein has a potential for clinical bedside use in helping for prognostic assessment.

296 allow us to immunophenotype patients at the bedside using temperature.

297 pidly move translation from the bench to the bedside, we believe that cooperative research efforts ha

298 erspective on CRT's evolution from "bench to bedside." We also comment on the task faced by electroph

299 patients strongly preferred handover at the bedside, while the nurses considered patients to be invi

300 This knowledge has translated to the bedside with implications for clinical practice and dire