ライフサイエンスコーパス: before reaching

1 em able to detect a SARS-CoV-2-like pathogen before reaching 0.01% cumulative incidence.

2 these mice died of severe diabetic symptoms before reaching 1 year of age.

3 eight loss and other clinical manifestations before reaching 100% mortality within 8 days after intra

4 se almost linearly at a rate of 0.9 mm Hg/mo before reaching 22 to 23 mm Hg at 10 months.

5 on was determined in blood and urine samples before reaching (225)Ac/(213)Bi equilibrium.

6 ulfilled the inclusion criteria exhibited VA before reaching 87% of maximum heart rate.

7 was better at higher ratios, but leveled off before reaching a 100% yield.

8 strengthens for a few initial atomic periods before reaching a constant value.

9 quested on average significantly fewer beads before reaching a decision than controls (3 vs 6 beads).

10 with different ground electronic properties before reaching a fully oxidized, metallic SrFeO(3) phas

11 many daily tasks, we make multiple decisions before reaching a goal.

12 outside of a hospital, approximately 60% die before reaching a hospital (presumed sudden cardiac deat

13 sed with increasing spermidine concentration before reaching a limiting value 40 nm.

14 aques appear and grow over a period of weeks before reaching a mature size.

15 two cycles to the computed number of cycles before reaching a metric of subfertility.

16 peaks of extremely high Akt phosphorylation before reaching a moderate steady-state.

17 iated with increased postoperative mortality before reaching a new baseline, particularly for electiv

18 lasmic tail at the COOH terminal are altered before reaching a new premature stop codon 38 amino acid

19 ining a volume fraction of 80% around 170 K, before reaching a non-magnetic state.

20 lls undergo multiple rounds of cell division before reaching a nonresponsive (i.e., tolerant) state.

21 s independent of the state of other subunits before reaching a permissive state, from which the chann

22 PA gradually increased over the initial week before reaching a persistent maximum.

23 ceeding via a transient triplet intermediate before reaching a planar singlet species.

24 The trial was terminated early for futility before reaching a planned enrollment of 200 participants

25 ise over 2 h (t((1/2)) approximately 20 min) before reaching a plateau at >1,400 nmol/g (ED(50) = 900

26 The antibody levels increased steadily before reaching a plateau in mice receiving the booster,

27 drivers) to 36.9 per 100,000 (17-year-olds), before reaching a plateau of 46.2 per 100,000 (18-year-o

28 ally increase over a period of several weeks before reaching a plateau that is stable 6 months after

29 ucose levels increased with maximum lifespan before reaching a plateau.

30 he ratios increased from 2.0:1:0 to 4.0:1:0, before reaching a plateau.

31 at unexpectedly declined by ~50% over 100 ms before reaching a stable plateau.

32 gher than the final value and then decreases before reaching a steady state.

33 observed to accelerate rapidly along a line before reaching a terminal velocity when their drag matc

34 n with a gradual loss of specific cell types before reaching a threshold for symptomatic onset.

35 uted by the plasma membrane cholesterol pool before reaching ACAT.

36 ty (51%), facial dysmorphism (38%) and death before reaching adulthood (16%).

37 y that an adolescent aged 15 years would die before reaching age 25 years.

38 aughters born to older mothers tended to die before reaching ages at which such senescent decreases c

39 pacity to be activated and repeatedly divide before reaching an anergic or replicative senescence sta

40 ed monotonically within the subitizing range before reaching an asymptotic limit at approximately thr

41 lected to transition to open-label treatment before reaching an end point.

42 Six patients withdrew before reaching an end point: 3 to receive commercial th

43 competition in the rhizosphere is inevitable before reaching and infecting roots.

44 ation, neural activation of the motor system before reaching, and straightness of their reach traject

45 ere similar to reptiles in that RM developed before reaching asymptotic size.

46 nly establish minimal regions of coinfection before reaching cells where coinfection was blocked.

47 release but were unable to terminate release before reaching completion.

48 dered exploratory and requires further study before reaching conclusions about efficacy.

49 efficacy and safety, as well as replication, before reaching conclusions about the clinical value of

50 l discriminations; the number of errors made before reaching criterion was greatest for the first few

51 hich suggests that loop extrusion is impeded before reaching CTCF.

52 these secondary outcomes require replication before reaching definitive conclusions.

53 hal and that the homozygous-null embryos die before reaching E12.5.

54 ntinue to rise by 6%-18% in future evolution before reaching equilibrium between operon gains and los

55 The transient time before reaching equilibrium is determined by PapI stabil

56 quantitatively measure ligand concentration before reaching equilibrium.

57 in 56% of patients, and 26% of patients died before reaching ESRD.

58 s interest to allow food items to accumulate before reaching for food.

59 ompared with their inextensible counterparts before reaching forces sufficient to cleave covalent bon

60 t antidepressant drugs require several weeks before reaching full biochemical efficacy and remission

61 icate that tissue oxygenation was restricted before reaching Hbcrit.

62 ponentially, but lose their growth advantage before reaching high frequencies.

63 tegrate temperature and humidity information before reaching higher brain centres.

64 examine the morphogenetic function of an ECM before reaching homeostatic equilibrium by analyzing de

65 the risk that the first such event is fatal before reaching hospital, particularly among people who

66 undergo a number of sequential folding steps before reaching its functional fold, i.e., the global mi

67 referentially populate the noncanonical fold before reaching its modern-day near-equal population of

68 epidermal cells and transmitting tract cells before reaching its ovule targets.

69 cling endosome and apical transport carriers before reaching its steady-state apical membrane localiz

70 a range DeltaT(A) approximately 0.015-0.018 before reaching its steady-state random coil configurati

71 are still significant challenges to overcome before reaching large-scale commercialization.

72 res also limits birds' thermal safety margin before reaching lethal levels.

73 to experience the birth of a younger sibling before reaching maturity.

74 opment, passing though several larval stages before reaching maturity.

75 ocytes developed tremors and ataxia and died before reaching maturity.

76 t observed from 8 hpf, but waned from 16 hpf before reaching maximal expression at 6 dpf, but this wa

77 These fibers appear to "zip" together before reaching mechanical equilibrium due to the existe

78 14)C offset was close to zero prior to GS-1, before reaching 'near-modern' values at ~12,660 cal BP,

79 t becomes a net ecosystem carbon source just before reaching net-zero and negative emissions.

80 ported from endosomes to the plasma membrane before reaching NPC1-containing late endosomes.

81 Before reaching peak values, EBOV viremia similarly incr

82 diverge following successive stress episodes before reaching persistent abnormal levels.

83 ment was voluntarily halted on Feb 16, 2014, before reaching planned enrolment (n=150) because of poo

84 The trial was stopped before reaching planned sample size due to the decrease

85 due to enhanced gas-to-particle partitioning before reaching plateaus at approximately C(14)-C(15), w

86 onse to experimental treatments stall growth before reaching post-synaptic targets.

87 hemocytes, carry melanotic capsules and die before reaching pupal stages.

88 otyls and expanded cotyledons and are lethal before reaching reproductive development.

89 ced lateral re-orientation in the deep crust before reaching shallower magmatic storage and the summi

90 e in the displacement distance up to 300 mum before reaching significant DeltaCSF.

91 fined databases the power-law line collapses before reaching smaller sized families.

92 Importantly, potential LT before reaching status 1a/1b and aggressive postoperativ

93 lb are the final stage in sensory processing before reaching target cortical regions, at which there

94 orals to a protective, sub-bleaching stress, before reaching temperatures that cause bleaching.

95 ed different secondary structure transiently before reaching the active state in the activation proce

96 Before reaching the alveoli, particles must transverse t

97 In FGF mutants, CVM cells die before reaching the anterior region of the TVM.

98 tratosphere during the initial eruption well before reaching the Asian monsoon deep convective region

99 and sequestered by the hydrosphere/biosphere before reaching the atmosphere.

100 ntation development, and severe degeneration before reaching the blastocyst stage.

101 d during two stages of the annual migration: before reaching the breeding grounds (northward migratio

102 y (Cryo-EM) analysis of the construct ending before reaching the CAD demonstrated that the N terminus

103 exocytic pathway transits through endosomes before reaching the cell surface.

104 o their native, fully inactive conformations before reaching the cell surface.

105 ss branching under increasing insulin levels before reaching the cell's insulin-resistant state, wher

106 the unchosen path on non-VTE laps to appear before reaching the choice point.

107 cdysone is first secreted into the hemolymph before reaching the CNS [3], our finding raised the ques

108 hough Liprin-alpha mutant R7 axons terminate before reaching the correct target layer, Liprin-beta mu

109 raphic, with little cross-whisker divergence before reaching the cortical network.

110 t undergo a complex metabolic transformation before reaching the critical 2'-deoxyzebularine 5'-triph

111 nd the rim-pore reaches its equilibrium size before reaching the critical pore size.

112 significant amount of CO2 either is released before reaching the depth at which arc magmas are genera

113 erms clay-rich marls completely devolatilize before reaching the depths at which arc magmatism is gen

114 over tens of picoseconds and 600 nanometers before reaching the diffusive transport limit.

115 herefore the number of amino acids unraveled before reaching the disulfide bond (n) facilitates the t

116 gerin(+) DCs that transit through the dermis before reaching the DLN.

117 ctive site toward subdomain 2, but dissipate before reaching the DNase binding loop (D-loop), which r

118 ted errors, mismatch extension, and transfer before reaching the end of the donor template were deter

119 cell extract, replication frequently stalls before reaching the end of the genome, causing the newly

120 ee transient migratory streams in the cortex before reaching the final laminar destination.

121 which move through a multilevel supply chain before reaching the finished product.

122 e-emission) corresponded to an emission well before reaching the generation of the radical anion and

123 and showed that the two proteins dissociate before reaching the Golgi apparatus.

124 ked carbohydrates, and were rapidly degraded before reaching the Golgi complex thus exhibiting a traf

125 Most patients with cardiac death die before reaching the hospital, which brought about a trem

126 networks, all of which terminated in moulins before reaching the ice edge.

127 ce mass gain is lost through oceanic erosion before reaching the ice front, and the calving flux is a

128 hat becomes mixed by the diffuse reflections before reaching the image sensor.

129 junction toward the anterior temporal lobe, before reaching the inferior frontal gyrus.

130 t of the COVID-19 pandemic, enrollment ended before reaching the initial target, leaving the trial un

131 ce the outer cell membrane and the cell wall before reaching the inner cell membrane for subsequent v

132 chromosome replication being resumed shortly before reaching the intracellular proliferation compartm

133 r, other energy barriers have to be overcome before reaching the major transition state.

134 s that this technology still has to overcome before reaching the market, and future perspectives.

135 at evergreen forest RUEs initially increased before reaching the mature stage (i.e., around 90 years

136 at the majority of target ribosomes bind SRP before reaching the membrane.

137 along one of the conical intersection seams before reaching the minimum energy conical intersection.

138 Under these conditions, the reaction stops before reaching the most thermodynamically stable produc

139 ckets and dry globular states numerous times before reaching the native conformation.

140 hrough the entorhinal and perirhinal regions before reaching the neocortex.

141 s must have ponded, producing an inland sea, before reaching the northern plains as enormous spillove

142 grade transport to cross the Golgi apparatus before reaching the nucleus to cause infection.

143 unds with lower binding affinity are ejected before reaching the olfactory receptor, rendering them s

144 Before reaching the OM, precursor unfolded OMPs (uOMPs)

145 of TOM is that TOM is almost fully degraded before reaching the open ocean.

146 intravascular space during its first passage before reaching the organs and spreading into the extrac

147 igher and is formed approximately 10 degrees before reaching the orientation in the post-stroke cryst

148 near-miss events-errors caught and corrected before reaching the patient-than MEDIC.

149 ayer, through which sun light must propagate before reaching the perovskite layer, may lower the powe

150 Both trial designs stopped for futility before reaching the planned maximum sample size.

151 rly following publication of a related study before reaching the planned sample size of 350 patients.

152 oplasmic reticulum through the Golgi complex before reaching the plasma membrane along microtubule tr

153 osomes (REs) located in dendrites and spines before reaching the plasma membrane.

154 ewly synthesized ZO-2 travels to the nucleus before reaching the plasma membrane.

155 of cadmium, Pca1 is targeted for degradation before reaching the plasma membrane.

156 o the NPC1-containing late endosome/lysosome before reaching the PM or the endoplasmic reticulum.

157 ffeine; 411, placebo) out of the 878 planned before reaching the prespecified futility threshold.

158 ansmembrane domains (TMDs) avoid aggregation before reaching the proteasome is unclear.

159 nary spaces through which filtrate must pass before reaching the proximal convoluted tubule.

160 aining the particles in the mixed layer just before reaching the pycnocline.

161 Because light must pass through MP before reaching the receptors, it filters significant am

162 atterns for identical action sequences, well before reaching the reward site.

163 ion, absorption, deposition, and degradation before reaching the sampling site.

164 rives mercury enrichment in marine sediments before reaching the seafloor.

165 wth layer and the extent to which hail melts before reaching the surface.

166 trosome polarisation is initiated but aborts before reaching the synapse and the granules do not pola

167 sm, then the signal could in principle decay before reaching the target and a stable spatial gradient

168 tection of siRNAs from premature degradation before reaching the target cells.

169 cline; symptomatic participants had declined before reaching the target doses.

170 hrough a cascade of Landau-Zener transitions before reaching the target state.

171 ecause most of the devices contact the blood before reaching the targeted regions.

172 The study was closed to accrual before reaching the targeted sample size, after the prim

173 ears to be no further evolution of this rate before reaching the transition state of folding.

174 ated sewage is discharged into water sources before reaching the treatment facility, potentially cont

175 less susceptible to microbial mineralisation before reaching the treatment works.

176 An implantation of the embryo before reaching the uterus could result in ectopic pregn

177 metrically into the nasal and dorsal regions before reaching the ventrotemporal retina.

178 ynapses to traverse a large number of states before reaching their bounds, or by changing the way the

179 se several membranous transport compartments before reaching their destinations.

180 he minimum accrual and are intended to close before reaching their end points, whereas trials are alm

181 ency' that ectotherms expend (or accumulate) before reaching their heat limits.

182 vesicles, to continue to the Golgi apparatus before reaching their membrane of residence.

183 es to face the many obstacles they encounter before reaching their metastatic site(s), whether these

184 eruptions as luminous blue variables (LBVs) before reaching their most likely end as supernovae, but

185 tein, motor neuron growth cones stop growing before reaching their muscle targets, or follow incorrec

186 uses crossing the acidic gastric environment before reaching their primary replication site, the inte

187 neurons appear to differentiate prematurely before reaching their target.

188 hat spend too much time at nonspecific sites before reaching their targets on DNA.

189 wed substantial shrinkage during dehydration before reaching TLP, in contrast with species originatin

190 relatively short-lived and disassemble well before reaching vesicle size.