ライフサイエンスコーパス: begin to

1 he previously dominant view that plants only began to actively moderate the Earth's surface with the

2 nt factors affecting lipotransfer as well as begin to address its oncological risks.

3 They also begin to address the relationship between in utero expos

4 We begin to address this by asking the following: (1) What

5 We begin to address this knowledge gap by conducting longit

6 To begin to address this question, we created 2 alleles to

7 Here we synthesize studies that are beginning to address this question by investigating fund

8 n chronically immunosuppressed patients, and begins to address the feasibility of kidney retransplant

9 While new approaches have begun to address these challenges, ultimately, additiona

10 inning in the early postnatal brain, neurons begin to aggregate near the ventricles of treated animal

11 r's yeast, even as experimental systems have begun to allow measurements in other contexts.

12 As an atypical pneumonia began to appear in December 2019, Zhou et al. worked wit

13 per microliter with no evidence that we have begun to approach complexity limits.

14 f plant-microbe interactions (MPMI), we have begun to ask ourselves "what are the major questions sti

15 nomic variation across human populations and begin to assemble a human pan-genome, these efforts will

16 mpling a diverse set of individuals, one can begin to assemble a pan-genome: a collection of all the

17 iofacial patterning and GnRH dysfunction and begin to assemble the functional network that regulates

18 le-containing covalent polymer networks have begun to attract attention in the context of water treat

19 Neurofeedback has begun to attract the attention and scrutiny of the scien

20 molecules of the immune system just recently began to be extensively studied.

21 ive yet mechanistically important issues can begin to be addressed.

22 versibility as electron and proton transfers begin to be decoupled.

23 red in increasingly specified ways, they can begin to be optimized for drug delivery in a more person

24 tates whose identity and importance are just beginning to be appreciated.

25 during enteric bacterial infection are only beginning to be characterized.

26 asibility of implementing such strategies is beginning to be confirmed.

27 eract with the extracellular matrix are just beginning to be elucidated.

28 r mechanisms, the evolution of which is just beginning to be explored.

29 hat extent domains can be engineered is just beginning to be explored.

30 Forecasting is beginning to be integrated into decision-making processe

31 the World Health Organization in 2017 and is beginning to be introduced in countries around the world

32 ntum information and computing that are only beginning to be realized.

33 ys underlying islet cell differentiation are beginning to be resolved, the cellular basis of islet mo

34 lar transitions during fibrogenesis are only beginning to be resolved.

35 One strategy beginning to be successfully leveraged is the use of end

36 o other neurodegenerative conditions and are beginning to be translated into clinical trials.

37 biology and functions of IL-34 are only now beginning to be uncovered.

38 d that the full scope of their roles is only beginning to be uncovered.

39 broblasts and promote tissue remodelling are beginning to be understood and will be an important rese

40 As the landscape of TIMCs is beginning to be understood, it opens up questions about

41 chondrial movement toward axon terminals are beginning to be understood, the frequency and function o

42 nitially orient the left-right body axis are beginning to be understood, the mechanisms that shape th

43 ciples of these regulatory networks are only beginning to be understood.

44 d the relevant mechanistic underpinnings are beginning to be understood.

45 tiple mechanisms of action that are only now beginning to be understood.

46 each of these pathways is conferred is just beginning to be understood.

47 lour, and fruit size and shape are only just beginning to be understood.

48 ns affecting adaptation in the wild are only beginning to be understood.

49 sms that regulate these differences are only beginning to be understood.

50 tooth eruption and tooth root formation are beginning to be unraveled.

51 ns of these developmental processes are just beginning to be unveiled.

52 The impact of these mutations has begun to be analyzed at a molecular level by modeling in

53 pathways during infection have only recently begun to be elucidated.

54 disorder whose scientific underpinnings have begun to be established in the past decade.

55 ic function and brain disorders has only now begun to be investigated.

56 sense and maintain cell wall integrity have begun to be revealed, including signals arising in the w

57 ly have the functions of these contact sites begun to be understood.

58 ex actions of BAF in vivo have only recently begun to be unraveled.

59 sumptions of PSF fitting hold and where they begin to break down.

60 mperature increases, bonds between the atoms begin to break, giving rise to molecular-scale fracture

61 The work presented here begins to bridge that gap in knowledge by showing how on

62 Nature offer a strong foundation on which to begin to build microbial diagnostics to detect cancer.

63 enetic enzymes in specific brain regions are beginning to build causal links between these epigenetic

64 Non-breeders began to care for eggs after male removal and further in

65 We are only just beginning to catalog the vast diversity of cell types in

66 cent finds of early ceremonial complexes are beginning to challenge this model.

67 al realms and melanopsin ganglion cells have begun to challenge the boundary between them, providing

68 d covered by this review), however, that has begun to change, with theory now frequently leading the

69 study to demonstrate invasion of human-RPEs, begin to characterize intracellular localization and sur

70 In conclusion, we begin to characterize the genetic regulation of serum le

71 (iPSCs), which were used to isolate EMVs and begin to characterize their cargoes.

72 clinical depression, and other disorders may begin to clarify how the effects spread through the enti

73 Tissue studies have also begun to clarify the meaning of changes in PET signal in

74 We recently began to collaborate with the RepeatsDB resource to impr

75 dom, transkingdom, and immune cross talk are beginning to come into focus, setting the stage for a ne

76 permeability in this chemical space are only beginning to come into focus.

77 Capturing transition-state ensembles begins to complete the catalytic energy landscape that i

78 mingham Institute of Forest Research (BIFoR) began to conduct Free Air Carbon Dioxide Enrichment (FAC

79 t only within the past two centuries have we begun to connect particular plant metabolites with speci

80 to eliminate trachoma by 2020, countries are beginning to control the transmission of trachomatous in

81 yr BP, inhabitants of this region began to create a landscape that ultimately comprised ap

82 egies provides an analytical method that can begin to decipher causal associations.

83 vity against Env-expressing target cells but began to decline after 3 to 6 weekly doses, coincident w

84 inescence per bacterium, and its persistence began to decline by 48 h.

85 In Pou3f4(y/-) mice, SGN density begins to decline by the end of the first postnatal week

86 ALB) was >= 30 years, the age when fertility begins to decline.

87 These studies have begun to decode the chemical logic that enables opioids

88 Here, we begin to deconvolute the process of signal bias from the

89 Fibrosis began to decrease by 1 year after surgery and continued

90 Amyloid-beta42 levels began to decrease in Alzheimer's disease cases a few yea

91 alis gene expression (RNA-Seq analysis), and began to define the impact of SL synthesis on its intera

92 Our findings begin to define a consensus sequence for ZMPSTE24 that h

93 These findings begin to define a mechanism for extracellular interactio

94 sity of function within the Scrib module and begin to define the elusive molecular functions of Scrib

95 Together, these findings are beginning to define an engram as the basic unit of memor

96 More recent work has now begun to define nuanced, stage-specific roles for Ikaros

97 mples from patients with lupus nephritis has begun to define the phenotypes of both infiltrating and

98 Crater began to drain and the summit caldera began to deflate, with the summit collapse ending on Aug

99 Today's genetic structure began to develop by 5,800 BP, followed by bi-directional

100 How and when infants and young children begin to develop emotion categories is not yet well unde

101 still do not know precisely when these cells begin to develop the selectivity.

102 A was enriched in DNs when a plaque was just beginning to develop.

103 ased with age in both groups (p<0.0001), and began to differentiate carriers from non-carriers when a

104 etermine the age at which NfL concentrations begin to differentiate between carriers of the presenili

105 , long before the androgenic gland primordia begin to differentiate, and exponentially throughout dev

106 ortical development and gets induced as NSCs begin to differentiate.

107 ative at carcasses when blowfly maggots have begun to digest the tissue, but that this social coopera

108 r neurons are recruited in a short burst and begin to discharge at high frequencies (up to >200 Hz).

109 more bacterial genomes are sequenced, we are beginning to discover their prevalence and their differe

110 Recent studies are beginning to dissect the mechanisms that make these MEK

111 oblem of inference-based decision making and begins to dissect the network of brain regions crucial f

112 the earliest age at which NfL concentrations begin to diverge between mutation carriers and non-carri

113 n both Pu'u O'o Vent and Halema'uma'u Crater began to drain and the summit caldera began to deflate,

114 quencing and analysis of gene expression has begun to dramatically increase our understanding of orga

115 To begin to elucidate how VU0364572 modulates cocaine self-

116 Together, these results begin to elucidate the brain-level molecular processes t

117 ncomplete, recent progress has allowed us to begin to elucidate the specific mechanisms supporting fi

118 elopments in RNA sequencing technologies are beginning to elucidate the cellular diversity present wi

119 Additionally, our work begins to elucidate the critical role of isotype for an

120 neuronal activity in preclinical models have begun to elucidate the contributions of the PFC and its

121 In recent years large-scale efforts have begun to elucidate the genetic and phenotypic diversity

122 Recent work has begun to elucidate the important roles of developmental

123 DPs apparently began to emerge during the aquatic-to-land transition, w

124 on was gradual, assuming that small villages began to emerge during the Middle Preclassic period (100

125 As new genetic tools began to emerge to study chlamydial genes in vivo, we sp

126 een that stability and environmental drivers begin to emerge when the lakescape, composed of many dis

127 iate when differences in HC and LC offspring begin to emerge.

128 Sex-specific synaptic connectivity is beginning to emerge as a remarkable, but little explored

129 We explore the numerous hit molecules beginning to emerge from high-content/high-throughput sc

130 n fetal programming of brain development are beginning to emerge in the literature.

131 al information on ABC sterol transporters is beginning to emerge, with published structures of ABCA1

132 PD-1 in regulating NK cell function is only beginning to emerge.

133 ses and their inhibitory mechanisms are just beginning to emerge.

134 tion rate and mRNA abundance under stress is beginning to emerge.

135 course correction, and a clearer picture is beginning to emerge.

136 tors manipulate nonimmunity pathways is only beginning to emerge.

137 pathway mutations in pediatric diseases has begun to emerge.

138 We provide both a guide to begin to empower the new generation of educators, scient

139 , facilitated discovery of therapeutics, and begun to enable investigation of virulence mechanisms at

140 ric contribution appears to have taken, from beginning to end, just ~30 Myrs, suggesting this is the

141 are now enabling vehicle electrification and beginning to enter the utility industry.

142 To begin to establish the global pattern of these outputs,

143 As we began to examine the role of CsrA in A. baumannii, we ob

144 ction risk as temperatures and precipitation begin to exceed species' historically observed tolerance

145 wo or more humans interacting together often begin to exhibit similar structures of behavioural varia

146 Accordingly, the vacuolar cargo begins to exit the Golgi near the midpoint of maturation

147 information from human and animal studies is beginning to expand insights regarding neurobiological s

148 While ocean global change biologists have begun to experimentally test how variability in environm

149 nce of HYAL2 on RNA splicing, these findings begin to explain the broad biological effects of HYAL2.

150 This begins to explain the contribution of common variants to

151 lding on these foundations, researchers have begun to exploit the predictable base-pairing properties

152 To begin to explore potential dynamic changes of the gut mi

153 To begin to explore the biological consequence of introduci

154 nt belowground components, we are still only beginning to explore the complex relationships between r

155 We are only beginning to explore the possibilities of this technolog

156 Therefore, researchers have begun to explore alternative therapeutic options.

157 A handful of studies have begun to explore the reverse inference: creating brain-t

158 initiation of tracheal development, endoderm begins to express Nkx2.1, and then mesoderm expresses th

159 At pressures above 30 mmHg, the model begins to fail, consistent with non-linear changes in co

160 in bacteria, transiently accumulates as FolE begins to fail, stimulates the interaction between ZagA

161 Here, Li and colleagues begin to fill these gaps by identifying the loss of the

162 This study begins to fill this gap in literature by testing the nul

163 RNAs begin to fold and function during transcription.

164 Proteins synthesized in the cell can begin to fold during translation before the entire polyp

165 ins are synthesized from N to C terminus and begin to fold during translation.

166 Nascent polypeptides begin to fold in the constrained space of the ribosomal

167 dest, deepest, and most voluminous lake that began to form over 30 million years ago.

168 ffold against which nascent polypeptides can begin to form structure in a highly coordinated, co-tran

169 When pathogenic Abeta seeds begin to form, propagate and spread is not known, nor ar

170 However, HMMs have only recently begun to gain traction within the broader ecological com

171 Emerging studies have begun to generate exciting insights about some fundament

172 communicate more complex meanings, children began to grammatically structure their gestures.

173 Yet, we are only beginning to grasp the drivers of terrestrial microbial

174 r, her symptoms continued to worsen, and she began to have dyspnea when she was at rest.

175 Artificial intelligence approaches are beginning to have considerable impact in improving diagn

176 The Montreal Protocol has begun to heal the Antarctic ozone hole and avoided more

177 are common challenges that nanotechnology is beginning to help address.

178 To begin to identify such candidates, we used the laminated

179 rences among species have been resolved that begin to identify the determinants that define grass cel

180 This work begins to identify the physiologic and pathogenic conseq

181 rals, and the hydrozoan Hydractinia, we have begun to identify bacterial cues that stimulate animal m

182 Predictive studies have begun to identify pathogen traits associated with emerge

183 Researchers have begun to identify the manifold roles that these cells pl

184 ch bacteria promote animal metamorphosis, we begin to illustrate how, and explore why, the developmen

185 rging body of social scientific research has begun to illustrate a logic to revenge, demonstrating wh

186 iques, it is encouraging that guidelines are beginning to include evidence from robust observational

187 genetics of CHC biosynthesis, which is just beginning to incorporate work on more insect taxa beyond

188 ) on day 8 (3 days after symptom onset) then began to increase again, from 21% (CI, 13% to 31%) on da

189 ptions to reduce patient risk, registrations began to increase in May, 2020, and reached higher numbe

190 idden for 15 years, at which point diversity began to increase in unfertilised plots.

191 duration when retinal acellular capillaries begin to increase.

192 , the risk of arterial thromboembolic events begins to increase 150 days before the date of cancer di

193 adolescents' views of their social position begin to independently relate to well-being is currently

194 Recent studies in neuroscience have begun to independently address the two components of inf

195 ates about major movements of people and has begun to inform on other important facets of the human e

196 , revealed that early forest-linked lineages began to invade seasonal savannahs during the late Mioce

197 During this period, many societies began to invest heavily in building monuments, which sug

198 ow that in young zebra finches that are just beginning to learn the structure of their species' song,

199 Recently, researchers have begun to leverage insights from regenerating and metamor

200 In doing so we can begin to link motor microcircuit pathology to specific d

201 Infants as young as 3 months have begun to link language and core cognitive capacities.

202 lls (OHCs), but not inner hair cells (IHCs), began to lose their third row of stereocilia and showed

203 As artificial intelligence (AI) systems begin to make their way into clinical radiology practice

204 few years, however, it appears the field is beginning to make progress.

205 terlink brain and brain-inspired devices are beginning to materialise.

206 ing embryogenesis and emerges when the heart begins to mature.

207 eripheral nerves in small animal models that begins to meet these constraints.

208 ting when stocks in the core-dominant sector begin to move in lock-step, presaging a dramatic move in

209 e of proliferation, and mature MTB cells had begun to move from the main body of the conceptus.

210 ion of TG is greater in CD28(-/-) mice, this begins to normalize with time and this normalization is

211 ill continue to grow and worsen if economies begin to open without the proper precautions, including

212 Previous retrospective studies have begun to outline the clinical course of breast implant A

213 Whereas recent studies have begun to outline the spatial organization of synaptic in

214 strategies, like acquaintance immunization, begin to outstrip them in minimizing outbreaks.

215 In this article, we review how recent effort begins to overcome this technical challenge, leading to

216 xperimental camera trap studies have already begun to play an important role in understanding the pre

217 lant life-history trade-offs, ecologists can begin to predict plant community structure at global sca

218 , which produced most of the world's coffee, began to prepare for an outbreak.

219 Diverse efforts in protein engineering are beginning to produce novel kinds of symmetric self-assem

220 ons in different fields of investigation are beginning to prove the relevance and effectiveness of [F

221 Evidence from multiple animal species is beginning to provide a mechanistic understanding of the

222 how the recent developments in genetics are beginning to provide social scientists with a powerful n

223 genetic relationship between T2D and CHD is beginning to provide the promise for improved prevention

224 ough single-cell RNA sequencing studies have begun to provide compendia of cell expression profiles(1

225 ecent experimental and modeling studies have begun to question this long-held belief.

226 Lastly, as clinics begin to re-open for routine appointments, protocols hav

227 As we begin to reach the limits of classical computing, quantu

228 As many low-income countries begin to reach the threshold at which countries transiti

229 Sediments from an active area of seepage began to reduce sulfate in a methane-dependent manner wi

230 ic transition, these structures degrade, and begin to reform in the months following metamorphosis.

231 pon injury, cardiac fibroblasts in the heart begin to remodel the myocardium by depositing excess ext

232 sented in a continuous series and eventually began to repeat.

233 l reduction in global gain when the stimulus began to repeat.

234 by less dense cytoplasm, recent studies have begun to report the opposite.

235 ble-layer sign became evident as the lesions began to resolve, and eventually this area was replaced

236 rdisciplinary structure-function studies are beginning to resolve the effect each interaction has on

237 reasing in early winter, well before sea ice begins to retreat.

238 Three studies in this issue of Cell begin to reveal the drastic and complex effects of fasti

239 In a new study, Li and Ma begin to reveal the mechanisms of confidence generation

240 ll-type specific manner during oogenesis and begin to reveal the relatedness in expression between ce

241 Our results begin to reveal the unique regulation of stem cell centr

242 These new studies are beginning to reveal how macromolecular assemblies of ded

243 nization at unprecedented resolution and are beginning to reveal the ways that cells co-opt the struc

244 onnectivity and physiological properties and begun to reveal aspects of its function.

245 Emerging studies have also begun to reveal critical roles for distinct innate immun

246 However, recent advances have begun to reveal that epigenetic modifications of chromat

247 mingly, the age-standardized rate of CVD has begun to rise in some locations where it was previously

248 o subwavelength scales, their resonant modes begin to scatter light into many spatial channels.

249 ging methods to infer cellular functions are beginning to shed new light on the interplay of componen

250 Such discoveries have begun to shed light on the pathophysiology of bipolar di

251 phic collapse, suggesting the focus of power began to shift to urban centers outside of the capital d

252 s by Consiglio et al. and Gruber et al. have begun to shine light on the immune drivers of this enigm

253 t majority of diagnoses happen once patients begin to show noticeable signs of illness.

254 Renewed interest in this area has begun to showcase the therapeutic potential that lies in

255 w applications of ecohydrological models are beginning to simulate small-scale water movement process

256 Thus, even for infants just beginning to speak their first words, the way in which a

257 nguages they will link to cognition: infants begin to specify which human languages they will link to

258 After ART was discontinued and as the virus began to spread, an apparently functional pDC response e

259 noncoding genome, and machine learning have begun to succeed.

260 and controlling matter at the microscale are beginning to take hold, suggesting new modular approache

261 he development of new functional devices has begun to take advantage of wrinkled surfaces.

262 provide examples of recent studies that have begun to take on this important next step in the literat

263 ut not subjective fatigue, declined from the beginning to the end of the mission.

264 From the beginning to the end of the study period, the mean weekl

265 ratory rate increased significantly from the beginning to the end of the trial.

266 With implantation, mouse stromal cells begin to transform into epithelial-like cells surroundin

267 nd discusses how these analyses have already begun to transform fundamental concepts in the field of

268 e away from a one-size-fits-all approach and begin to treat each patient with therapies that are effe

269 g research on coordination chemistry that we began to truly understand the nature of the coordination

270 Together, these findings begin to uncover how innate immune signaling is dysregul

271 experiments and new modeling techniques are beginning to uncover the general control principles unde

272 Researchers are also beginning to uncover the genetic architecture of complex

273 Over the past 5 years, several studies have begun to uncover the links between the classical signal

274 Recent data have begun to uncover the molecular mechanisms by which infla

275 To begin to understand how CPSs have an impact on Bacteroid

276 in early March 2020 in order to discuss and begin to understand neurological presentations in patien

277 To begin to understand phenotypic plasticity of a long-live

278 h hydroxychloroquine-with caution as we only begin to understand the biology, epidemiology, and poten

279 world data from electronic health records to begin to understand the clinical relevance of these inhi

280 To begin to understand the mechanism by which beta-arr1 tog

281 To begin to understand the mechanisms regulating VE-cadheri

282 ity learning during reward-guided actions to begin to understand the neuronal basis of this form of l

283 ld populations of Drosophila melanogaster To begin to understand the processes that underlie this vir

284 To begin to understand the underlying cellular mechanisms a

285 We are just beginning to understand the diversity of the peripheral

286 ars, considerable advances have been made in beginning to understand the genetic substrates that unde

287 We are only beginning to understand the mechanisms by which the huma

288 However, we are only beginning to understand the mechanisms governing cilia g

289 and chronic pain mechanisms, but we are only beginning to understand their mechanistic basis.

290 ss whose function and regulation we are just beginning to understand.

291 In recent years, we have begun to understand how membrane remodelling is coordina

292 360 years, only in the last 20 years have we begun to understand the basic mechanisms that underlie t

293 Only recently have we begun to understand the ecological and evolutionary effe

294 ority of human cancers, and we have recently begun to understand the mechanisms by which cancer cells

295 These studies have begun to unearth many novel genetic variants associated

296 Taken together, these findings begin to unravel biophysical underpinnings that contribu

297 To begin to unravel the complexities of GABAergic circuits

298 We are just beginning to unravel the cell-specific, physiological ro

299 thermore, we discuss how recent studies have begun to unravel how these fundamental class C GPCR feat

300 cells in vitro, and co-culture platforms are beginning to yield insights into the complex interaction