ライフサイエンスコーパス: begin with

1 methods requires a large number of cells to begin with.

2 te in which it is more active than it was to begin with.

3 xtension and scene construction in memory to begin with.

4 ry support at birth, it may be reasonable to begin with 21% to 30% oxygen and to base subsequent oxyg

5 The STEP-KOA intervention began with 3 months of an internet-based exercise progra

6 To begin with, 48 potential active components in SND agains

7 red via homologous recombination (HR), which begins with 5' end resection, mediated by exonuclease co

8 ric clinical event sequences most frequently began with a Giardia-specific test, whereas adult sequen

9 either sententially constrained or not, and began with a salient or non-salient mouth movement.

10 development for the treatment of psoriasis, began with a survey of six-membered heteroaryl groups in

11 We begin with a brief historical review of the development

12 We begin with a brief introduction to natural and artificia

13 We begin with a brief introduction to the architectural div

14 We begin with a brief introduction to the early history of

15 We begin with a brief overview of the evolution of 2D TMD r

16 We begin with a comparison of the core signaling pathways o

17 We begin with a description of the differences in the chemi

18 Initially we begin with a description of the fundamentals related to

19 These calculations begin with a detailed description of a system, including

20 We begin with a detailed fine-grained spatial model in whic

21 In this Review, we begin with a discussion of both established and novel me

22 We begin with a discussion of reactions where metal hydride

23 We begin with a focused review of the current literature, f

24 We begin with a general introduction to circadian rhythms a

25 We begin with a historical discussion of N(2) functionaliza

26 In this Perspective, we begin with a historical flashback to early reports befor

27 We begin with a historical survey and then compare attribut

28 We begin with a review of the clinical landscape of pancrea

29 We begin with a short introduction to the wide variety of p

30 od for sulfondiimine synthesis that does not begin with a sulfide or a thiol, and instead employs two

31 In preparation, begin with a theoretically sound definition of self-care

32 arter of mycobacterial mRNAs are leaderless, beginning with a 5'-AUG or GUG initiation codon.

33 Beginning with a cytological screen of genome stability

34 athways in the tree shrew are also reviewed, beginning with a description of the organization and cen

35 Beginning with a diverse microbial community generated f

36 omoted pathway for this net 1,5-Cu-migration beginning with a doubly dearomative imidoyl-Cu-ene react

37 Beginning with a high-throughput screening hit, we ident

38 Beginning with a primary causal target, we extend this t

39 imulated single-particle growth trajectories beginning with a single tiling unit.

40 We used serial passage in ribavirin, beginning with a variety of ribavirin-sensitive and riba

41 This transition predominantly begins with a 0.5 degrees C increase from the west coast

42 Transmembrane signaling begins with a 2- angstrom ligand-induced displacement of

43 nd handedness was observed when the sequence begins with a beta-hGly residue instead of a (S)-beta-Ca

44 elped us learn that the most preferred route begins with a bidentate chelate binding of deprotonated

45 This article begins with a brief discussion of the proposed biosynthe

46 This review begins with a brief review of the strengths and limitati

47 The visual phototransduction cascade begins with a cis-trans photoisomerization of a retinyli

48 The manuscript begins with a critical discussion regarding the potassiu

49 This article begins with a description of the scope of the problem, i

50 This evidence begins with a discovery that transcripts of one or more

51 The review begins with a discussion of flexible and stretchable dev

52 This section begins with a discussion of methods that are more chemic

53 The germinal center (GC) reaction begins with a diverse and expanded group of B cell clone

54 This Perspective begins with a focus on the catalytic H-cluster of [FeFe]

55 patterns suggest that infant gut succession begins with a functionally variable cohort of taxa, adep

56 Drug discovery usually begins with a high-throughput screen (HTS) of thousands

57 This reprogramming begins with a loss of SOX10-mediated differentiation fol

58 g the challenges of a top-down approach that begins with a many-body system, the size of which can hi

59 Early diagnosis begins with a medical history and involves using neuroim

60 mbers need not be identified initially-MISST begins with a minimal representative set of known struct

61 ls, we propose an alternative mechanism that begins with a Ni(2) -mediated coupling of (Me(3) Si)CHN(

62 Repair begins with a phase mediated by inflammatory monocytes (

63 We offer an efficient new approach that begins with a potentially infeasible maximum parsimony r

64 that oral CMV infection in infants typically begins with a single virus that spreads inefficiently to

65 Metastasis begins with a subset of local tumor cells acquiring the

66 The review begins with a summary of the proteins and the anchoring

67 The paper begins with a summary of traditional approaches to nurse

68 ntraocular lens (IOL) technology has already begun with a number of recent innovations.

69 Chromothripsis accumulates, beginning with aberrant interphase replication of bridge

70 The clinical syndrome begins with abnormal placentation with subsequent releas

71 ude that the most likely catalytic mechanism begins with abstraction of a hydrogen atom from C-4 (or

72 ccurs throughout an epidemiologist's career, beginning with academic instruction before workforce ent

73 e modern version of the RNA World Hypothesis begins with activated ribonucleotides condensing (nonenz

74 ms supporting spoken language comprehension, beginning with age-related physiological decline.

75 se of our argument that human ultrasociality began with agriculture.

76 sequence of primary limiting factors to GPP beginning with air temperature in winter and proceeding

77 est, whereas adult sequences most frequently began with an antiparasitic prescription.

78 each guideline, the decision-making process began with an assessment of overall cardiovascular risk.

79 Initial reports in the 1980s began with an emphasis on 2nd and 3rd row late transitio

80 ion of water as life's matrix must, however, begin with an acknowledgment that our understanding of i

81 We begin with an overview of the importance of the Wulst in

82 In this review, we begin with an overview of the major challenges GxE studi

83 We begin with an overview of these schemes and illustrate t

84 graph to a series of wet chemical reactions, beginning with an acidic copper(II) chloride and hydroge

85 c enantioselective synthesis of such esters, beginning with an alkyl halide (derived from an aldehyde

86 Beginning with an assessment of a patient's pre-ICU func

87 malignancy, is primarily diagnosed visually, beginning with an initial clinical screening and followe

88 ceiver Operating Characteristic (ROC) chart, beginning with an over-motivated state with many false p

89 Searching for food, friends, and mates often begins with an airborne scent.

90 XCI begins with an establishment phase during which Xist RNA

91 The last part of this review begins with an extensive, comparative, and critical surv

92 This review begins with an overview of the current biologically and

93 All that we view of the world begins with an ultrafast cis to trans photoisomerization

94 sensorimotor circuits that guide exploration begins with an understanding of the pattern of motor out

95 y due to the near-ideal miscibility of Y6 to begin with and indicates that strategies for developing

96 The process begins with approval from ASCO's Clinical Practice Guide

97 encoding genes by RNA polymerase II (Pol II) begins with assembly of the pre-initiation complex (PIC)

98 aracterization of proteins using NMR methods begins with assignment of resonances to specific residue

99 Beginning with atrial synchronous right ventricular (RV)

100 mptoms appear between 5 and 10 years of age, beginning with blindness and seizures, followed by progr

101 activate synapses that had few receptors to begin with, but that additional remodeling events are re

102 Beginning with CaV 3.2 channel inhibition, Ni(2+) was sh

103 C-labelling study suggests that the reaction begins with cleavage of the unstrained C-C bond, followe

104 The model described platelet activation beginning with CLEC-2 receptor clustering, followed by S

105 This apparent symbiosis begins with close physical contact and nutrient exchange

106 Collisional events began with collision of India and the Trans-Tethyan subd

107 We begin with contextual factors, including demographic var

108 ational repair of double-strand breaks often begins with creation of initiating 3' single-stranded DN

109 Here, beginning with cryo-electron microscopy structures of th

110 PheCAP begins with data from the EMR, including structured data

111 This work has begun with data from humans and can be extended to other

112 Beginning with dC11, which does not fold, the transition

113 Our analysis begins with definitions of ethically relevant terms.

114 The process begins with deposition of carbon nanotube (CNT) or graph

115 The cascade of care in our model begins with diagnosis of hepatitis C infection through a

116 and cost, management of constipation should begin with dietary fiber supplementation and stimulant a

117 itical species, this environmental filtering begins with differential recruitment and post-recruitmen

118 with in vivo development of the distal lung, beginning with differentiation of cells into anterior fo

119 amed within a developmental perspective that begins with disturbances in glutamate synaptic developme

120 vealed that pitch classes have rainbow hues, beginning with do-red, re-yellow, and so forth, ending w

121 rovides my reflections on these studies that began with enzymology and the use of cultured mammalian

122 ated in a stepwise hierarchical process that begins with extensive laboratory-based structural analys

123 Sex determination of the gonads begins with fate specification of gonadal supporting cel

124 smitted by the respiratory route and illness begins with fever, cough, coryza, and conjunctivitis fol

125 at endogenous daily rhythms in the fetal SCN begin with few noisy oscillators on E14.5, followed by w

126 uential assembly process in living bacteria, beginning with formation of the AcrAB subcomplex and sug

127 iscuss pattern and process in domestication, beginning with general findings about early domesticatio

128 The procedure begins with genetic editing of mouse ESCs via CRISPR-Cas

129 The growth-to-maturation transition begins with germinal vesicle or nuclear envelope breakdo

130 Beginning with graphene on untreated thermal oxidised si

131 The condition began with high-frequency hearing impairment in all fami

132 s in plants, using four vegetal examples and beginning with HPLC-MS/MS in precursor ion scan mode, af

133 The latter begin with hydrogen abstraction (HA) from Ch by a reacti

134 enerally accepted model that protein folding begins with hydrophobicity-driven chain collapse.

135 Monitoring of safety began with ICD implant and continued up to 5 years.

136 gnitive decline and dementia risk may really begin with improving educational quality and access in c

137 ity, particularly for a tumor that typically begins with inactivation of a single gene.

138 elopments in the surgical management of NEC, beginning with indications for surgery and following wit

139 Beginning with individuals from Phoenician/Punic sites (

140 ding a comprehensive overview of their uses, beginning with initial applications through to the prese

141 n a nativist view, the developmental process begins with innate prescribed solutions, and experience

142 itus, obesity and cardiovascular disease and begins with intrahepatic triacylglycerol accumulation.

143 ermined during the preceding cell cycle that begins with invasion by a single, asexually committed me

144 better understand these clinical disorders, beginning with iPSCs generated from a patient with PTSx

145 g characteristics of free radical chemistry, beginning with its rich and storied history.

146 ns from molecular dynamics trajectories that begin with known protein structures.

147 ypothesized to involve a cycle of behaviours beginning with leading edge extension.

148 Beginning with library design, a genome-scale screen can

149 Often, relevant mechanisms that begin with lifestyle choices and lead to cardiovascular

150 e global biodiversity crisis, but extinction begins with loss in abundance of individuals that can re

151 This thrilling journey began with mechanistic studies on a beta-globin enhancer

152 We began with minimalist assumptions about the intrinsic pr

153 tified a time-dependent pathological cascade beginning with mitochondrial oxidant stress leading to o

154 egies are currently used, a stepped approach beginning with more simple care that is progressed if th

155 My career as an accidental nutritionist began with my immersion in cholera control, a cyclone di

156 Two viable routes were developed beginning with N-TIPS-pyrrole or with 4-oxo-2-pentene an

157 Lead optimization, beginning with narrower-spectrum, weakly active compound

158 A two-step treatment regimen, beginning with neoadjuvant metformin+venetoclax to induc

159 present from the onset of brain development, beginning with neural crest cell migration.

160 that force generated at the parasite surface begins with no preferential directionality but becomes d

161 ative technological culture, arguing that it begins with non-social cognitive skills that allow human

162 The clinical course in affected individuals began with normal development or mild developmental dela

163 and break repair by homologous recombination begins with nucleolytic resection of the 5' DNA strand a

164 Assessment for heart failure begins with obtaining a medical history and physical exa

165 Outbreaks began with one to three index case(s) with large estimat

166 site usage by HIV-1 produces 5'-capped RNAs beginning with one, two, or three 5'-guanosines ((Cap)1G

167 This 10-week summer program begins with one week of training on computational biolog

168 at electrical breakdown in thunderstorms can begin with oppositely-directed fast breakdown of negativ

169 Prevention of osteoporosis in adulthood begins with optimizing bone health in early life.

170 ental data for a wide range of V1 phenomena, beginning with orientation selectivity but also includin

171 pts are markedly more stable than mRNAs that begin with other nucleotides.

172 different approach to that taken previously, beginning with our understanding of the molecular mechan

173 decline in the ecological role for cod that began with overfishing in this ecosystem will likely be

174 We propose an evolutionary scenario beginning with pathogen-associated molecular pattern(s)

175 Activation of the core kinase cassette begins with phosphorylation of the kinase MST1/2 (also k

176 This high-throughput approach begins with polyhistidine-tagged protein substrates expr

177 t engender unique pharmacological properties began with Portoghese's work directed toward opioid rece

178 Human lung growth and development begins with preconception exposures and continues throug

179 Beginning with predetermined ratios of phosphorylated to

180 delines have identified a Chain of Survival, beginning with prevention and early identification of ca

181 The processing of downloaded data files began with quality checks using NOISeq, followed by WGCN

182 nations) and to control stereochemistry when beginning with readily available racemic starting materi

183 betaarr-dependent actions begin with recruitment of betaarr to the phosphorylated

184 Endurance exercise begun with reduced muscle glycogen stores seems to poten

185 ophisticated machine with purified proteins, beginning with regulated CMG assembly and activation.

186 Decoding of this information begins with regulated transcription of genomic DNA into

187 r a stepped-care model in which patients may begin with relatively nonintensive treatment, with incre

188 Beginning with reports about increased S100B levels in d

189 romic repeats)-associated (Cas) protein Cas9 begin with RNA-guided DNA unwinding to form an RNA-DNA h

190 reflect a long co-evolutionary history that began with rudimentary, mutually-stabilizing interaction

191 on an Orbitrap Tribrid mass spectrometer and begins with selection of a parent ion in the MS scan, fo

192 iation of the Vgamma9Vdelta2 T cell response begins with sensing of pAg via the intracellular domain

193 ggests that value-driven attentional capture begins with sensory modulations of distractor representa

194 these materials within the postgraphene era began with silicene in 2010 and quickly progressed to th

195 Here, beginning with single-cell RNA sequencing, we identified

196 Zippering begins with slow N-terminal association followed by rapi

197 We show that neurogenesis in sea star larvae begins with soxc-expressing multipotent progenitors.

198 to advance through a series of transitions, beginning with spore germination and culminating with es

199 hosphoproteome at seven developmental stages beginning with stage VI oocytes and ending with two-cell

200 proaches for comparing two protein sequences begin with strings of letters (amino acids) that represe

201 What began with studies showing that cofactor availability dr

202 nal processing of viscerosensory information begins with synaptic gating at the first central synapse

203 ponent signaling pathway on model membranes, beginning with T cell receptor (TCR) activation and endi

204 The process begins with template DNA transcription by NUCLEAR RNA PO

205 tion of O(2) -dependent micro-organisms that began with the autotrophic eukaryotes.

206 The story we present began with the discovery of glucocorticoid receptors in

207 transcription in lambda, the study of which began with the discovery of the Rho transcription termin

208 ssible role of sleep in memory consolidation began with the early studies of Jenkins and Dallenbach (

209 This reaction began with the growth of a cerussite shell on top of cal

210 This interdisciplinary field began with the implementation of silicon circuits for bi

211 tion for addressing noncommunicable diseases began with the need to address the epidemic of tobacco-c

212 s that the first stage of the origin of life began with the onset of a primitive nonenzymatic version

213 deltoides The discovery of lignin regulators began with the quantitative genetic analysis of the xyle

214 Her wide-ranging career began with the study of protein folding and molecular ch

215 ication and Endgame Strategic Plan 2013-2018 began with the synchronized global replacement of trival

216 Stereochemical definition began with the synthesis of (2S,3S)-2-ethyl-3-methylpent

217 Catalytic reactions begin with the action of Lewis acidic B(C(6)F(5))(3) and

218 To study the dose-response relationship, we begin with the assumption that the external and internal

219 We begin with the demystification of regression models, as

220 Both protocols begin with the differentiation of hPSCs into definitive

221 initial stage of spinogenesis is thought to begin with the emergence of actin-rich dendritic filopod

222 We begin with the history of aquaporin zero (AQP0), the mos

223 of disease, and some (p-tau217 and p-tau181) begin with the initial increases in aggregate amyloid-be

224 oural and physiologic function, most studies begin with the injection of an engineered virus, often a

225 f the release of synaptic vesicles generally begin with the movement of vesicles from the cloud into

226 We begin with the myometrium and its myocytes and describe

227 ts and the predictive takeoff ensure flights begin with the prey visually fixated and directly overhe

228 r 1200 mg or 600 mg long-acting rilpivirine, beginning with the 1200 mg dose.

229 or the observed clamping effect of complexin beginning with the acceptor t-SNARE complex and the subs

230 Each sequential stage of the pathways beginning with the cellular uptake, intracellular transp

231 ained population contraction and stagnation, beginning with the cold episode of the Younger Dryas and

232 We used a demographic projection model beginning with the country population in the baseline ye

233 es and their utility toward N(2) activation, beginning with the d-block metals from Group 4 to Group

234 nt developments within the pyroptosis field, beginning with the discovery of Gasdermin D (GSDMD) as a

235 interest in polyP experienced a renaissance, beginning with the discovery of polyP as phosphate sourc

236 zontal cells (HCs) and amacrine cells (ACs), beginning with the early stages of postmitotic developme

237 s agree that this was a multi-stage process, beginning with the exploitation of natural fires and end

238 Beginning with the first isolation of graphene, mechanic

239 2018 calls for the phased withdrawal of OPV, beginning with the globally synchronized cessation of tO

240 reflect on the evolution of microbe hunting, beginning with the history of pre-germ theory epidemiolo

241 Beginning with the index admission, we estimated inpatie

242 combination of complex biochemical processes beginning with the initial insult and lasting for days,

243 w focused on modern, FDA-approved hypnotics, beginning with the introduction of benzodiazepines, limi

244 Beginning with the library design, the entire protocol c

245 Beginning with the nitro-NHC, we form an amine-NHC termi

246 marking developmental genes for activation, beginning with the onset of zygotic gene expression.

247 ns converging on the left entorhinal cortex, beginning with the perirhinal cortex and shifting throug

248 Beginning with the preservation of the first soluble com

249 of rheumatoid arthritis (RA) spans decades, beginning with the production of autoantibodies against

250 Beginning with the superposition rule for genuine partia

251 gin withdrawal of oral polio vaccines (OPV), beginning with the type 2 component (OPV2), through a gl

252 or a phased withdrawal of oral polio vaccine beginning with the type 2 component, introduction of ina

253 Nitrogen fixation by nitrogenase begins with the accumulation of four reducing equivalent

254 Perception of the thermal environment begins with the activation of peripheral thermosensory n

255 Mammary gland development begins with the appearance of epithelial placodes that i

256 tep in RQ biosynthesis, in worms the pathway begins with the arylamine precursor AA or 3HAA.

257 ukaryotic cells, protein synthesis typically begins with the binding of eIF4F to the 7-methylguanylat

258 activation loop is crucial for catalysis and begins with the conserved DFGmotif.

259 presented model, each new calculation cycle begins with the correction of the components' concentrat

260 The fabrication begins with the covalent conjugation of capture DNA prob

261 tion instead follows a two-step pathway that begins with the creation of disordered clusters of 10-20

262 It begins with the design and characterization of the first

263 acquired (1D/2D NMR and RDCs), the procedure begins with the determination of the molecular constitut

264 This begins with the development of an understanding of the p

265 This review begins with the discussion of the sensing mechanisms in

266 l photoconductivity, the degradation process begins with the disintegration of grains rather than nuc

267 a pro-inflammatory signaling cascade, which begins with the disruption of epithelial barrier integri

268 omplexes reveals that side chain restriction begins with the enzyme-substrate complex and persists th

269 Synovial joint development begins with the formation of the interzone, a region of

270 spectroscopy of intermediates, the reaction begins with the formation of Ti(3+)-AlH(3) complexes.

271 o P1 virions follows a distinct pathway that begins with the incorporation of DarA and Hdf and conclu

272 Clathrin-mediated endocytosis (CME) begins with the nucleation of clathrin assembly on the p

273 masome complex following infection or injury begins with the oligomerization of the upstream inflamma

274 cascade of protein-protein interactions that begins with the opening of the N-terminal domain of cTnC

275 Intracellular collagen assembly begins with the oxidative folding of ~30-kDa C-terminal

276 The new technique begins with the passage of one of two straight needles e

277 The reaction begins with the photoinduced electron transfer from CsPb

278 Cell division in Escherichia coli begins with the polymerization of FtsZ into a ring-like

279 The protocol begins with the preparation of a SCIDY precursor for FPE

280 In budding yeast, centromere establishment begins with the recognition of a specific DNA sequence b

281 Homo sapiens phylogeography begins with the species' origin nearly 200 kya in Africa

282 The route begins with the synthesis of two chiral pool-derived fra

283 iphered an early-stage assembly process that begins with the targeting of Dot/Icm components to the b

284 Scaffold assembly begins with the trimerization of alpha-chains into proto

285 yndrome coronavirus 2 (SARS-CoV-2) infection begins with the viral spike protein binding to the human

286 plex history of migration is thought to have begun with the arrival of people sharing ancestry with N

287 Clinical translation of this work has begun with the novel viewer being used in 5 TES patients

288 lted in many scientists not knowing where to begin with their projects.

289 f extracellular vesicles in these processes, beginning with their known role in delivering potential

290 Pioneering research studies, beginning with those using Drosophila, have identified s

291 entire process of amyloid fibril formation, beginning with thousands of free monomers and ending wit

292 We begin with three key insights from scholarship and pract

293 VEPART begins with time course experimental data for a sample p

294 long terminal repeat (LTR) retrotransposons, begins with transcription by RNA polymerase II followed

295 and 5 oral doses administered alternatively, beginning with transdermal dose.

296 igand-gated ion channels, their gating cycle begins with transitions from a ligand-free closed state

297 tempts at addressing this unmet medical need begin with understanding the cellular response to HHV-6

298 It suggests that binding begins with VAMP721, and subsequently with SYP121, there

299 To begin with, we have introduced organic semiconductors (O

300 en immunotherapy for patients with allergies begins with weekly escalating doses of allergen under me