ライフサイエンスコーパス: bell shape

1 oss the pure ESM membrane but with a steeper bell shape.

2 rrent-voltage (I-V) relationship for ICa was bell shaped.

3 se curve of GRP-stimulated DNA synthesis was bell shaped.

4 3-O-[(R)-3-hydroxymyristoyl]-GlcNAc are both bell-shaped.

5 The V/K(ne) pH profile is bell-shaped.

6 d probability of having African ancestry was bell-shaped.

7 permine, the k(cat)/K(amine)-pH profiles are bell-shaped.

8 second-order rate constants of inhibition is bell-shaped.

9 tes it at low concentrations, resulting in a bell-shaped activation profile.

10 HIV RNase H with Mn2+ or Co2+ ions generated bell-shaped activity dose-response curves.

11 c-Jun exhibits a bell-shaped activity on androgen receptor-mediated trans

12 H253A, K227A, H253A/K227A, and D234N remain bell-shaped, although their significantly lower activiti

13 or p-wave scattering with its tell-tale dumb-bell shape and no 90 degrees yield.

14 Starch granules showed round and bell shape and some irregular cuts on their surface with

15 ociation constant (k(lim)/K(d)) versus pH is bell-shaped and characterized by two macroscopic pK(a) v

16 tion of free enzyme with free cytochrome) is bell-shaped and closely resembles that of kox/Kd(cyt c),

17 he matrix metalloproteinase (MMP) family are bell-shaped and exhibit neutral pH optima.

18 (cat)/K(m) for URI from Escherichia coli are bell-shaped and indicate that one group must be unproton

19 ting with the l(o) phase, the OTP profile is bell-shaped and lies above that in the pure ESM membrane

20 ce of the fast central release component was bell-shaped and similar to that of I(Ca) in both cell gr

21 The pH profile of H224Q sHS is bell-shaped and similar to those reported for other MMPs

22 voltage dependence of the Ca2+ transient was bell-shaped and the maximum was centered at approximatel

23 r, binding data deviate from a stereotypical bell shape, and more binding occurs than expected at alk

24 nd the two components of central release was bell shaped, and the magnitude of each release component

25 citive component as a function of voltage is bell-shaped, and decreases with frequency.

26 Plots of activity versus log [metal ion] are bell-shaped, and the inhibitory phases of the profiles h

27 al evolution of Ca(2+) spark frequencies was bell-shaped, and the maximal spark frequency was reached

28 the data show that the size distribution is bell-shaped, and there is an approximately 40-A differen

29 en to separate the approximately symmetrical bell-shaped areas (negatives) from the skewed tails (pos

30 s for the Y82F enzyme-catalysed reaction was bell-shaped as for the wild-type protein.

31 these inverted relationships, explaining the bell-shaped behavior.

32 3 to dissociate from the DNA, resulting in a bell-shaped binding curve.

33 r PAD in response to 0.1-100 microM 5-HT was bell-shaped but in the capsaicin pre-treated group, a no

34 mutations shifted the peak of the InsP(3)R1 bell-shaped Ca(2+) dependence from 0.2 micro M to 1.5 mi

35 In [3H]ryanodine binding measurements, bell-shaped Ca2+ activation/inactivation curves were obt

36 all three mammalian InsP3R isoforms display bell-shaped Ca2+ dependence in physiological range of Ca

37 y InsP3 without shifting the peak of InsP3R1 bell-shaped Ca2+ dependence.

38 The bell-shaped Ca2+-dependence curve of type I InsP3R is id

39 Ca2+ for all three InsP3R1 isoforms; 3) the bell-shaped Ca2+-dependence is wider for the InsP3R1-SII

40 pS) than the InsP3R1-SII(+) (81 pS); 2) the bell-shaped Ca2+-dependence peaks at 200-300 nM Ca2+ for

41 Bell-shaped cell spreading curves encompassing all subst

42 do not respond to RANTES with the classical bell-shaped chemotactic response curve, suggesting that

43 lution structure reveals an asymmetric, dumb-bell-shaped complex with 4-fold symmetry, a length of 14

44 The structure of dsRBD exhibits a dumb-bell shape comprising two tandem linked dsRNA-binding mo

45 With these constructs, the bell-shaped concentration dependence of leukocyte migrat

46 tokines like IL-8, and also has the familiar bell-shaped concentration dependence seen for CXC cytoki

47 st-noncompetitive antagonist hybrids produce bell-shaped concentration-response curves, whereas the a

48 response at higher concentrations, producing bell-shaped concentration-response curves.

49 ar Ca2+ and [3H]noradrenaline release with a bell-shaped concentration-response profile; maximum enha

50 The k(cat)/K(m) value for the peptide is bell-shaped, consistent with a requirement that the nitr

51 e-channel Ca2+ current (iCa) rather than the bell-shaped current-voltage (I-V) relation of macroscopi

52 onditions, Hg(II) bioavailability followed a bell shaped curve as DOM concentrations increased, both

53 a coli and Aquifex aeolicus LpxC displayed a bell-shaped curve (EcLpxC yields apparent pKa values of

54 We calculate the bell-shaped curve and show that, if materials can be eng

55 te constant versus pH profiles were fit to a bell-shaped curve for all adducts.

56 PtNHase was found to exhibit a bell-shaped curve for plots of relative activity versus

57 CtNHase was found to exhibit a bell-shaped curve for plots of relative activity vs pH o

58 The acidic pK(a) in the bell-shaped curve is due to the phenolic hydroxyl of Tyr

59 We show that a bell-shaped curve of cleavage activation is obtained as

60 Analysis at different pH values produced a bell-shaped curve of the WT enzyme, but D387G exhibited

61 esulted in mitotic arrest with a symmetrical bell-shaped curve over time.

62 -direction the dependence of kcat of pH is a bell-shaped curve that is described by pKaS of 6.4 and 1

63 distinguishable from the second phase of the bell-shaped curve that was obtained in the absence of ha

64 nectin concentrations tested and shifted the bell-shaped curve upwards.

65 In general, a bell-shaped curve was obtained for each of the MT-MMPs i

66 ergent concentration dependent, exhibiting a bell-shaped curve with its maximum activity near the cri

67 nase (MMP) catalysis is described by a broad bell-shaped curve, indicating the involvement of two uns

68 ct of heparin with all FXa derivatives was a bell-shaped curve, which disappeared if the ionic streng

69 The ANG pH-rate profile is a classic bell-shaped curve, with pK(1) = 5.0 and pK(2) = 7.0.

70 of log k(cat)/K(m) versus pH is a distorted bell-shaped curve, with slopes of +1 on the acid side an

71 at n = 3, and then declines: the result is a bell-shaped curve.

72 ing channels as a function of log10(Ca) is a bell-shaped curve.

73 was dosage dependent on the inducer, with a bell-shaped curve.

74 cose with a response profile that followed a bell-shaped curve.

75 The 'bell-shaped' curve relating cytosolic Ca(2+) concentrati

76 the trough concentrations obtained from the bell-shaped curves are comparable to normal plasma level

77 Apparently corresponding bell-shaped curves displaying the pro-oxidant effect of

78 th log k cat/ K m and log k cat conformed to bell-shaped curves for which an inverse solvent kinetic

79 he mutants as a function of pH display broad bell-shaped curves that are similar to the wild-type enz

80 the pH-dependence of V(max) and V/K describe bell-shaped curves, consistent with the hypothesis that

81 trations (10(-1) to 10(5) units/ml) produced bell-shaped curves, demonstrating that inhibition occurs

82 Instead of the expected narrow bell-shaped cytoplasmic free Ca2+ concentration ([Ca2+]i

83 we show that in contrast to IL-8, where the bell-shaped dependence arises from the effects of CXCR1/

84 rmediate at 505 nm is affected by pH, with a bell-shaped dependence for the forward rate constant, k(

85 Unlike interfering with the bell-shaped dependence of InsP(3)Rs to [Ca(2+)](i), CT9

86 wever, these synthetic lipids give rise to a bell-shaped dependence of membrane permeability on [Chol

87 two p K a values previously observed by the bell-shaped dependence of the LpxC-catalyzed reaction.

88 arcus theory of electron transfer predicts a bell-shaped dependence of the reaction rate on the react

89 ude of the caged ADP tension transient had a bell-shaped dependence on Ca(2+), reaching a maximum at

90 open probabilities for PC-2 and S812A show a bell-shaped dependence on cytoplasmic Ca(2+) but there i

91 centration, whereas the type I isoform has a bell-shaped dependence on cytoplasmic Ca2+.

92 e constants did not exhibit a characteristic bell-shaped dependence on heparin concentration.

93 currents, the membrane capacitance showed a bell-shaped dependence on membrane potential with a peak

94 ve previously shown that MshB activity has a bell-shaped dependence on pH with pK(a) values of approx

95 d to Zn(2+)-LpxC; both metalloenzymes have a bell-shaped dependence on pH with similar pK(a) values,

96 In particular, movement amplitude showed a bell-shaped dependence on stimulus frequency, with a pea

97 tion kinetics, and the noise has a predicted bell-shaped dependence on the activation states of the e

98 er, the rate of charge recombination shows a bell-shaped dependence on the inverse temperature, first

99 2+)](i) transient amplitudes and I(Ca) had a bell-shaped dependence on V(m), but [Ca(2+)](i) reached

100 reasonably well the experimentally observed bell-shaped dependencies of bovine serum albumin or gela

101 These traits also showed a bell-shaped dependency on exogenous ABA, and their regul

102 y blocked by cobalt, and exhibited a similar bell-shaped dependency on voltage with a peak response a

103 elongation and whole-root hydraulics, had a bell-shaped dependency on WD, displaying stimulation und

104 The pH-activity profile was bell-shaped, depending on the ionization state of two gr

105 The pH dependence of the activity was bell-shaped, depending on the ionization state of two gr

106 The pH profile was bell-shaped, depending on the ionization state of two io

107 ially after lavage and were sigmoidal with a bell-shaped derivative function.

108 eric species built from the association of a bell-shaped dimer, a process we characterized by electro

109 Slopes of eGFR had a bell-shaped distribution (mean [SD], -1.5 [-2] ml/min pe

110 ind the Dorsal gradient maintains a constant bell-shaped distribution during embryogenesis.

111 ns exhibit a 60% incidence of diabetes and a bell-shaped distribution of insulin levels as related to

112 ted earlier at initial flower opening with a bell-shaped distribution pattern.

113 f subjects to clopidogrel followed a normal, bell-shaped distribution, with a mean and standard devia

114 verall occupancies of ~8 P(i) (+/- 5) with a bell-shaped distribution; the highly phosphorylated frac

115 doses of 0.1, 0.3 and 1.0 mg/kg, produced a bell-shaped dose response effect on DA efflux in the mPF

116 fic IgE and challenged with Pen a 1 showed a bell-shaped dose response for secretion, with optimal Pe

117 The ORL-1 antagonist also eliminated the bell-shaped dose-response curve for buprenorphine-induce

118 Thus, Cas exhibits an unusual bell-shaped dose-response curve in response to EGF stimu

119 and high concentrations, reminiscent of the bell-shaped dose-response curve obtained for TBS-induced

120 ) versus 5-HT(7) receptors, may underlie the bell-shaped dose-response curve via a mechanism of 'cros

121 he presence of tetrodotoxin, NMDA produced a bell-shaped dose-response curve with stimulation of phos

122 ed the GTPase activity following an inverted bell-shaped dose-response curve, whereas when EF-2 and r

123 uced pMF was dose dependent, but exhibited a bell-shaped dose-response curve.

124 ions in both pMHC affinity and dose produced bell-shaped dose-response curves and different optimal p

125 In addition, two narrow bell-shaped dose-response curves were identified with ma

126 e sinks for the free inhibitor, resulting in bell-shaped dose-response curves.

127 rease in its inhibitory effect, resulting in bell-shaped dose-response curves.

128 tly increased cell proliferation albeit with bell-shaped dose-response kinetics.

129 mber of these analogues were found to have a bell-shaped dose-response profile in the alpha1 beta2 ga

130 a distinct pharmacological profile without a bell-shaped dose-response relationship or tachyphylaxis

131 tment increased the PKCalpha activity with a bell-shaped dose-response relationship peaking at 10 nM,

132 d each affected the rotational behavior in a bell-shaped dose-response relationship producing increas

133 s 3-5 each affected rotational behavior in a bell-shaped dose-response relationship producing maximal

134 ents but to a lesser extent, indicative of a bell-shaped dose-response relationship.

135 PKCalpha-PLC-phospholipase D (PLD)-mTOR in a bell-shaped, dose-dependent manner requiring the Ca2+ se

136 Many tektites have elongated or 'dumb-bell' shapes due to their rotation mid-flight before sol

137 with the 5' flanking region of Tac1 showed a bell-shaped effect of SDF-1alpha on luciferase activity

138 The bell-shaped effect of the field frequency with maximum a

139 nct binding sites for halides comes from the bell-shaped effects observed when the second-order rate

140 Extreme values of Psi0 lead to asymmetric, bell-shaped extension-rotation profiles with sharp maxim

141 ed by circular dichroism exhibit reversible, bell-shaped folding and unfolding transitions, implying

142 al V-delta L relationship was converted to a bell shape following the magnitude of ICa when internal

143 rofiles for both k(cat) and k(cat)/K(m) were bell-shaped for all of the HDAC isozymes, with pH optima

144 (M)-pH profiles with N(1)-acetylspermine are bell-shaped for all the mutants; the similarity to the p

145 t)/K(m)(L-OSHS) versus pH profile of eCGS is bell-shaped for both reactions.

146 The resistive component is bell-shaped for both voltage and frequency.

147 erating effects on heparin concentration was bell-shaped for ZPI reactions with both factors Xa and X

148 f STIM1, CRAC current was a highly nonlinear bell-shaped function of Orai1 expression and the minimum

149 ies or nonrecombining chromosome region is a bell-shaped function of the mutation rate: at some point

150 ma distribution, which is in contrast to the bell-shaped Gamma distribution when the gene effects wer

151 speed tuning curves of MT neurons should be bell-shaped (Gaussian) as a function of the logarithm of

152 Saturating HCII dependences and bell-shaped heparin dependences of the fluorescence chan

153 In computational models, such a bell-shaped "hill of activity" is commonly assumed to be

154 (R2N)PPn(+*) further show that the symmetric bell-shaped hole distribution distorts and shifts toward

155 merizes via the FAD-binding domain to form a bell-shaped homodimer in solution with a maximal dimensi

156 Cyclosporine treatment caused bell-shaped improvements in cardiac output, stroke volum

157 h model, our data suggest that MK has a dumb-bell shape in solution composed of independent N- and C-

158 The voltage-contraction relationship was bell-shaped in Na+-free solutions (to eliminate the Na+

159 tate concentration-response curves that were bell-shaped in response to either glutamate or AMPA.

160 tionship between contraction and voltage was bell-shaped in the absence of Na-Ca exchange.

161 The time course of D was bell-shaped, indicating it was an intermediate.

162 me modest effects, the shapes of neither the bell-shaped k(cat)/S(0.5)-pH (and related functions) plo

163 The bell-shaped logarithmic GAG dependences fit an obligator

164 rge of the membrane motor is manifested as a bell-shaped membrane potential dependence of the membran

165 The crystal structure of PfPA28 reveals a bell-shaped molecule with an inner pore that has a stron

166 trong plasmonic coupling effect, and (iii) a bell-shaped nanostructure that can effectively amplify t

167 For both proteins, the bell shape of this dependence shows that they autoxidize

168 ctural units (dialkyammonium groups) in dumb-bell-shaped organic molecules template the assembly of e

169 otation and cross-stream translation along a bell-shaped path.

170 ore fatty acid synthesis enzymes displayed a bell-shaped pattern of expression between 5 and 13 days

171 males), and, respectively, showed a U- and a bell-shaped pattern with age.

172 rmal eyes and optic nerve crush alone showed bell-shaped patterns of change: approximately 50% below

173 is qualitatively different from the largely bell-shaped patterns typical of EMG activity associated

174 the chemical shift analysis, nonuniform and bell-shaped peak intensity profiles, and limited proteol

175 The concept of bell-shaped persistent neural activity represents a corn

176 ssociated with a rate constant that showed a bell-shaped pH dependence indicative of participation of

177 Furthermore, we conclude that the simple bell-shaped pH dependence of k(cat) and k(cat)/K(m) for

178 The bell-shaped pH dependence of permeability suggests that,

179 Furthermore, the wild-type hydratase shows a bell-shaped pH dependence of the kcat/Km with pKa values

180 o-step mechanism is also consistent with the bell-shaped pH dependence of the reaction rate.

181 In addition, normal bell-shaped pH dependence on the reaction catalyzed by M

182 The bell-shaped pH dependence upon pK(app)'s of 7.1 and 9.1

183 -)(CoA), and V/K(homoserine) all exhibited a bell-shaped pH dependence with apparent pK's of 6.6 and

184 (kcat/Km)app and kred/Kd exhibit comparable bell-shaped pH dependence with pKa values of 6.4 +/- 0.2

185 lated cytochrome c(3+) reduction displayed a bell-shaped pH dependence with the protonation of a grou

186 ecovery to the colored ground state showed a bell-shaped pH dependence, controlled by two pKa values

187 Formation of this complex exhibits bell-shaped pH dependence, with pKa values of 6.5 and 7.

188 ameter klim/Kd for the fast phase exhibits a bell-shaped pH dependence, with two pKa values of 9.3 +/

189 A bell-shaped pH profile and salt concentration dependence

190 s ranging from minutes to hours, exhibited a bell-shaped pH profile for k(bkdn), typical of the pH-ra

191 The simulation data reveal a bell-shaped pH profile for the total helix content, in a

192 he k(cat)/K(M) value for spermine exhibits a bell-shaped pH profile, with an average pK(a) value of 8

193 The k(cat)/K(m) value for BESPM exhibits a bell-shaped pH profile, with pK(a) values of 9.8 and 10.

194 Both bell-shaped pH profiles are quantitatively accounted for

195 pKa values range from 7.0 to 8.7) exhibited bell-shaped pH profiles whose maxima were distinct for e

196 strated that the mutant proteases maintained bell-shaped pH profiles, as well as suicide-inhibitor su

197 finity of MKP3 for oxyanion, and restore the bell-shaped pH rate profile for the MKP3-catalyzed react

198 ysis of bulky polycyclic substrates exhibits bell-shaped pH rate profiles in the absence of ERK2.

199 from RNase A and serve to generate a similar bell-shaped pH versus k(cat)/K(M) profile for RNA cleava

200 Bell-shaped pH versus rate profiles were observed for V(

201 These measurements show bell-shaped pH-rate curves for each enzyme in the presen

202 A bell-shaped pH-rate profile for k(cat) and k(cat)/K(m) i

203 yl phosphate (4NPP), the reaction exhibits a bell-shaped pH-rate profile for kcat/KM indicative of ca

204 bstrate Cdk2-pTpY/CycA, however, did yield a bell-shaped pH-rate profile with a pK(a) of 6.1 for the

205 stingly, Cdc25B does not exhibit the typical bell-shaped pH-rate profile with small molecule substrat

206 gnificant shift in pK(1) to higher pH in the bell-shaped pH-rate profiles (k(cat)/K(m)) for several p

207 Both YopH and Cdc25A exhibit bell-shaped pH-rate profiles for the hydrolysis of mNBP,

208 The existence of bell-shaped pH-rate profiles for the K73A variant sugges

209 ypoxanthine and 1,N(6)-ethenoadenine follows bell-shaped pH-rate profiles, indicating that AAG-cataly

210 erified by experiment, are consistent with a bell-shaped pH/rate profile but are at odds with hydroly

211 a 1 gamma 2S delta constructs resulted in a 'bell-shaped' pH titration relationship.

212 MAD2 complex is cell cycle regulated with a "Bell" shaped profile and peaks at prometaphase.

213 A bell-shaped profile of the observed rate constant for an

214 diates was measured and exhibited an unusual bell-shaped profile over the pH range of 5.0-9.5 with a

215 ate of assembly depends on the pH level in a bell-shaped profile, and two pK(a) values that are in go

216 for isoleucyl 4-cyanothiazolidide yielded a bell-shaped profile, with pK(a)=5.0 and pK(b)=7.6.

217 he pH dependence of the IMPDH reaction shows bell-shaped profiles for kcat and the kcat/Km values for

218 The broad and bell-shaped profiles representing the diversity of the V

219 Bell-shaped profiles were observed for k(cat) and k(cat)

220 Bell-shaped profiles were observed for kcat and kcat/Km

221 en expression for the urease reaction with a bell-shaped rate-pH dependence.

222 In contrast, an inverted bell-shape relationship was found for NC valency and lys

223 Among all nelfinavir-treated patients, a bell-shaped relationship between adherence and the risk

224 The standard view postulates a bell-shaped relationship between adherence to therapy an

225 atients with detectable viremia, there was a bell-shaped relationship between Gag-specific CD4+ T cel

226 A distinct bell-shaped relationship between lung volume and carbon

227 These characteristics produce a bell-shaped relationship between the apparent dissociati

228 ch case, superoxide production had a similar bell-shaped relationship to the reduction state of cytoc

229 A bell-shaped relationship was also observed for the proba

230 A bell-shaped relationship was found between NC targeting

231 tatic conditions, cell migration speed had a bell-shaped relationship with fibronectin concentration.

232 unctional conductance (G(j)), which showed a bell-shaped relationship with junctional potential (V(j)

233 nt of shortening blocked by nifedipine had a bell-shaped relationship with voltage, whereas the "nife

234 We observe an asymmetric, approximately bell-shaped, relationship between the average intracellu

235 Bell-shaped relationships between adherence and resistan

236 te but produced an increase (potassium) or a bell-shaped response (rubidium) with a supercoiled templ

237 nocytes, neutrophils, and macrophages with a bell-shaped response curve in a pertussis toxin-sensitiv

238 e.g. dihydrorhodamine) previously revealed a bell-shaped response to co-generated (*)NO and O(2) flux

239 The activity of the enzyme exhibited a bell-shaped response to divalent cations and pH.

240 Similar bell-shaped results were found when the GRT analysis was

241 at which superoxide oxidation ensued yielded bell-shaped ring currents.

242 ly speckled intensity pattern into a single, bell-shaped spot, sitting on a low energy background.

243 elationship in 200 microM cadmium (Cd2+) was bell-shaped, supporting a role of ICa,L rather than VDCR

244 ified size related changes in wake dynamics, bell shape, swimming and turning kinematics of two speci

245 le Pb2+ concentration was found to exhibit a bell shape that spans approximately 3 orders of magnitud

246 xhibit distinct pH dependence (the former is bell-shaped, the latter sigmoidal), again consistent wit

247 al ischemia-reperfusion (MI/R) injury with a bell shape therapeutic profile.

248 These data generate classic bell-shaped time-constant-potential curves.

249 nd C(20):C(20:3Delta11,14,17)PE, an inverted bell-shaped Tm profile was detected in the plot of Tm ag

250 have shown that the information conveyed by bell-shaped tuning curves increases as their width decre

251 Numerosity-selective neurons showed bell-shaped tuning curves with one of the presented nume

252 ivities of large populations of neurons with bell-shaped tuning curves.

253 Simulations are performed for both an oblate bell shape using a paddling mode of swimming and a prola

254 ng a paddling mode of swimming and a prolate bell shape using jet propulsion.

255 of episodes, each consisting of a distinct, bell-shaped velocity profile (submovement) that rarely o

256 pear to be consistent with the arm-referent, bell-shaped, visual target tuning curves and target sele

257 A bell-shaped voltage dependence and modest sensitivities

258 hannel current (I(Ca)), and it shifted their bell-shaped voltage dependence leftward by approximately

259 -cAMP, membrane-permeable form of cAMP), the bell-shaped voltage dependence of cytosolic Ca2+ transie

260 ISO dramatically broadened the bell-shaped voltage dependence of intracellular Ca(2+) t

261 Confocal imaging revealed that the bell-shaped voltage dependence of SR Ca(2+) release is a

262 ials and the I-V relationship maintained its bell-shaped voltage dependence.

263 nd total amount of released Ca2+ exhibited a bell-shaped voltage dependence.

264 mplitude of the Ca2+ transient also showed a bell-shaped voltage dependence.

265 plitude of the Ca2+ transient again showed a bell-shaped voltage dependence.

266 ntraction in physiological [Na+] and a broad bell-shaped voltage-contraction relationship was observe

267 K(+)-based, Na(+)-free solution exhibited a 'bell-shaped' voltage dependence of the L-type Ca2+ chann

268 in's voltage sensor imparts a characteristic bell-shaped, voltage-dependent nonlinear capacitance (NL

269 ies rapidly decay with decreasing Re for all bell shapes when Re<10.

270 Dose response curves showed bell shapes where activity was low at low and high conce

271 tinociception display ceiling effects or are bell shaped, which have been attributed to the partial a

272 ance spectra of visual pigments have a broad bell shape with the peak, being called lambdamax.

273 The V profile is bell shaped with slopes of 1 and -1, giving pKa values o

274 voltage dependence of phasic contraction was bell-shaped with 0 Na+, became much loss bell-shaped wit

275 was bell-shaped with 0 Na+, became much loss bell-shaped with 10 mM Na+ and with 20 mM Na+ the phasic

276 We found that the distribution is nearly bell-shaped with a peak at 50 base pairs (bp) upstream o

277 The (catR)/ versus pH profile of ytCBS is bell-shaped with a pH optimum of 8.3, and the pK(a) valu

278 The pH-k(cat) profile is bell-shaped with a pK(a) of 6.4 +/- 0.1 for the ascendin

279 he pH dependence of k(cat)/K(m,phosphite) is bell-shaped with a pK(a) of 6.8 for the acidic limb and

280 ip (assessed 45 min after DPAT injection) is bell-shaped with an ED50 approximately 1 mg/kg on the as

281 The pH dependence of V/K was bell-shaped with apparent pKs of 6.5 and 8.3.

282 By contrast, the doxorubicin response was bell-shaped with high doses failing to increase H2AX pho

283 The activity dependence on pH was bell-shaped with highest activity between pH 6.8 and pH

284 ate 2b, which lacks a 6-carboxyl group, were bell-shaped with limiting slopes of unity on both sides

285 dase activity and beta-lactam acylation were bell-shaped with maximal activity at pH 8.0-8.5.

286 tionship predicted by the CICR hypothesis is bell-shaped with no contraction at ECa.

287 profile of V/K for L-ribulose 5-phosphate is bell-shaped with pK values of 5.94 and 8.24.

288 the substrate Abz-LPETG-Dap(Dnp)-NH(2) were bell-shaped with pK(a) values of 6.3 +/- 0.2 and 9.4 +/-

289 versus pH profiles with and without CaM were bell-shaped with the ionization of a group at pK(a) of 7

290 ons in LiCl with and without MgCl2 were both bell-shaped with the pH optima in the neutral range.

291 or the observed first-order rate constant is bell-shaped with two ionizable groups of pK(a) 4.9 and 5

292 tion spectra of visual pigments have a broad bell shape, with the peak being called lambda(max).

293 aF/F versus voltage curve, from sigmoidal to bell-shaped, with a maximum at approximately +30 mV.

294 taining a pro-alpha factor cleavage site was bell-shaped, with a maximum near pH 4.0.

295 (III) as a function of SCN- concentration is bell-shaped, with a trough comparable with normal SCN- p

296 pH dependence of kcat/Km for L-kynurenine is bell-shaped, with apparent pKa's of 6.25 +/- 0.05 on the

297 e of kcat/Km for 3-hydroxykynurenine is also bell-shaped, with apparent pKa's of 6.49 +/- 0.07 and 8.

298 rves for these T-cell activation markers are bell-shaped, with different maxima and midpoints, depend

299 The plot of log k(cat)/K(m) versus pH is bell-shaped, with fitted pK(a) values of 6.76 +/- 0.09 a

300 The k(cat)/K(sarc) pH profile is bell-shaped, with pK(a) values of 8.8 and about 10; the

301 against Ac2-l-Lys-D-Ala-d-Ala (kcat/Km) was bell-shaped, with pKa values at 6.9 and 10.1.