ライフサイエンスコーパス: bench

1 EtCO(2) was compared with alveolar CO(2) (bench).

2 ventilator breaths reflected alveolar CO(2) (bench).

3 young researchers to not stay away from the bench.

4 evaluated using waterborne simazine as test bench.

5 es have been performed at a real engine test bench.

6 DOTA injection into CSF was performed on the bench after which the mice underwent T1 mapping using a

7 Our in-depth bedside-to-bench analysis uncovers the molecular mechanism underlyi

8 robably bridge the translational gap between bench and bedside in the near future.

9 of risk factors to AF pathogenesis from both bench and bedside studies.

10 studies between DNIC and CPM, gauged between bench and bedside, are key for the development of analge

11 ay explain some of the disparity between the bench and bedside, as well as emerging avenues for combi

12 -directional movement of information between bench and bedside.

13 science, focusing on transitions between the bench and bedside.

14 In bench and cadavers, similar capnograms were reproduced w

15 in approximately 10 d, with 2 d of hands-on bench and computational effort.

16 es of fastidious anaerobes inoculated on the bench and held at ambient or refrigerator temperature fo

17 ence communication and outline an agenda for bench and social scientists--driven by current social-sc

18 onments, researchers often need to leave the bench and venture into the field.

19 from two public VS databases (DUD-E and GPCR-Bench) and resulted in an average EF of 9.75 and 13.70,

20 eal and simulated M-IOLs, both optically (on bench) and visually (measured visual acuity in patients)

21 opathies serve as a prototype for bedside to bench, and back to the bedside, practice of evidence-bas

22 test the automatic resonator detuning on-the-bench, and subsequently evaluate it in a 1.5 T MRI scann

23 s validated by experimental data from both a bench- and a large-scale MDC system.

24 Bench- and air-stable 1-methoxy-2,2,6,6-tetramethylpiper

25 onella and mycobacteria across a transect of bench- and pilot-scale hot water experiments carried out

26 treatment, exemplifying a successful bed-to-bench-and-back approach.

27 FICANCE STATEMENT We have used a "bedside-to-bench" approach to investigate the functional regulation

28 By slightly modifying the optical bench arrangement, the spectrometer now enables a fast a

29 experiment in our laboratory, with follow-up bench assays demonstrating good correspondence between t

30 n combined fine-mapping, bioinformatics, and bench-based approaches to functionally characterize all

31 h experience in clinical, translational, and bench-based research in fibrotic lung diseases was conve

32 cation that allows medical professionals and bench biologists to prioritize and visualize genetic var

33 onal resources are increasingly available to bench biologists, tailored ongoing education is necessar

34 eneration of causal research conducted using bench, clinical, and population strategies.

35 Our first bench comparison of susceptibility of different stent de

36 data might support the idea of a 'bedside to bench' concept, whereby results from clinical trials of

37 Noting the paucity of wet-bench data regarding combinatorial effects of ABA and in

38 ection were similar to those generated using bench dehydration, but indicated 50% loss of conductivit

39 This wide gap between bench discoveries and clinical applications is mainly be

40 Vina (with EF = 1.48/3.16 in DUD-E and GPCR-Bench), DOCK 6 (2.12/3.47 in DUD-E and GPCR-Bench), PoLi

41 Using a bench dynamometer, the emissions from the following mixt

42 imental methods, which are not only prone to bench effects and artifacts but are also time-consuming,

43 Bench experiments showed a low mean bias for P0.1vent co

44 study, we combined mathematical models with bench experiments to identify a core regulatory circuit

45 ence of ABA elicited stomatal closure in wet bench experiments, but not in our in silico model.

46 nge of in silico functional analyses and wet bench experiments, our findings highlight new biological

47 By bridging SD with data from bench experiments, we demonstrate methods to (1) account

48 oration to advanced analysis of results from bench experiments.

49 er, the experiments on a dynamic engine test bench focus on the impact of the pore-size distribution

50 tion CUT&Tag requires less than a day at the bench, from live cells to sequencing-ready barcoded libr

51 However, to date, the "genomic bench" has not worked itself to the clinical thrombosis

52 ides as an example where improvements at the bench have been inspired and validated using single-mole

53 ause, thorough experimental standards at the bench, in the clinic, and within the community must prio

54 o) conditions identical to the catalyst test bench including the presence of water vapor.

55 lates were manipulated and/or tested on open benches, including by procedures that could generate inf

56 Interventions: The Friendship Bench intervention comprised 6 sessions of individual pr

57 nt of N2 (delta(15)N2) was monitored via gas bench isotope ratio mass spectrometry (GB-IRMS) for 21 d

58 In Bedside to Bench, Maria Kleppe and Ross L. Levine look at recent cl

59 ostdischarge mortality was 50%, a prognostic bench mark for hospice referral.

60 ying capacity of the cornea, and a potential bench mark for validating theoretical modelling of stres

61 eltaE(p) value of 0.26 V in Fe(CN)(6)(3-/4-) bench mark solution.

62 ion only, and show that it is an appropriate bench-mark for comparing different hardware.

63 monic NPs under physiological conditions, as bench-marked against the well-established PEG ligands.

64 Rate theory modeling, bench-marked against this data, suggests a crucial role

65 less than 10% relative error compared to the bench-marked multi-point method in mice and dogs and all

66 One of the preferred tasks for bench-marking such devices is automatic speech recogniti

67 After bench-marking, the algorithm has been applied to determi

68 se results were also validated using optical bench measurements.

69 eceiving continuous chest compressions, 2) a bench model, and 3) experiments with human cadavers.

70 Bench models of coronary bifurcation lesions demonstrate

71 form for titrations either on the laboratory bench or for in situ measurements in environmental or di

72 into different shapes, and is stable on the bench or under salt water.

73 -Bench), DOCK 6 (2.12/3.47 in DUD-E and GPCR-Bench), PoLi (2.2 in DUD-E), and FINDSITECcomb2.0 (2.90

74 ated manufacturing techniques, and extensive bench, pre-clinical, and clinical testing, lead failure

75 ee sets of 12 repetitions of four exercises: bench press, dumbbell curl, dumbbell squat, and standing

76 A bench prototype system based on this scheme was previous

77 Plasmodium vivax bench research greatly lags behind Plasmodium falciparum

78 and trainees were prevented from performing bench research.

79 uinone (DBBQ), were treated using a modified bench scale collimated beam device, mimicking UV treatme

80 oa 11S globulin purification starting at the bench scale using Ultra15 centrifugal filter devices.

81 evice enables clog-free cell retention for a bench-scale (350 mL) perfusion bioreactor that continuou

82 Bench-scale 3-D printed reactors were employed to determ

83 With modeling, and experiments at both bench-scale and field-scale, we demonstrate that reducin

84 Two bench-scale AnMBRs were operated in single-phase (SP) an

85 of experiments were conducted with parallel bench-scale AS reactors treating municipal wastewater wi

86 "High-concentration" and "low-concentration" bench-scale batch plasma reactors were used to effective

87 A bench-scale breakthrough curve with a NdFeB magnet leach

88 high-resolution mass spectrometry, following bench-scale chlor(am)ination.

89 We report a three-stage bench-scale column extraction process to selectively ext

90 developed and validated using data from the bench-scale DCMD treatment of synthetic wastewaters.

91 water collected from Long Island Sound in a bench-scale direct contact MD system to investigate the

92 inless steel (SS) as the cathode placed in a bench-scale electrochemical reactor.

93 (x) sites from molecular first-principles to bench-scale electrolyzers operating at industrial curren

94 Bench-scale experiments and physiochemical property pred

95 Bench-scale experiments were carried out for 24 h using

96 Bench-scale experiments were performed to assess uptake

97 Bench-scale experiments were performed to evaluate virus

98 In this work, bench-scale experiments were performed, using model brac

99 The approach integrated bench-scale experiments, an in situ spectroscopic techni

100 The sludge was then incinerated on a bench-scale fluidized bed reactor in a series of experim

101 Subsequently, a bench-scale fluidized-bed reactor was developed, applyin

102 We used a bench-scale flume to study the fate of 19 parent pharmac

103 The process is systematically optimized at bench-scale for gingerols infusion and subsequent candyi

104 Quantifying the performance of the bench-scale gas recovery system in terms of its ability

105 Bench-scale jar tests demonstrated that both MeI-treated

106 Bench-scale jar tests using three different source water

107 ication conditions were identified following bench-scale liquid hot water pretreatment.

108 with and without the presence of sediment in bench-scale microcosm studies.

109 olidone (PVP)-coated AgNPs were evaluated in bench-scale moving bed biofilm reactors (MBBRs), achievi

110 We use a bench-scale prototype machine to synthesize graphene on

111 The integrated continuous bench-scale reactor system produced 18 g/L of C16-C18 tr

112 omparison, we studied biofilm formation in a bench-scale reverse osmosis (RO) system using the same f

113 Using kinetic modeling and bench-scale RO experiments, we demonstrate that the low

114 ng a continuous stirred reactor coupled to a bench-scale sequencing batch reactor, we observed sustai

115 This bench-scale study evaluated the influence of dissolved m

116 OM) on arsenic mobilization during MAR, this bench-scale study examined arsenic mobilization from ars

117 The current bench-scale study found that severe phosphorus limitatio

118 In this bench-scale study, arsenic mobilization from arsenopyrit

119 identify biocake proteins on membranes in a bench-scale submerged membrane bioreactor (MBR).

120 el processes that govern solvent behavior to bench-scale testing, through process engineering and pro

121 This report describes results of a bench-scale treatability study to evaluate the efficacy

122 PANTHER is widely used by bench scientists, bioinformaticians, computer scientists

123 lows, challenging its adoption by nonexpert, bench scientists.

124 ing with the appearance of resources to help bench-side biologists become skilled at computational da

125 In the bench simulation of concrete processing, only 0.4-0.5% o

126 of particular benefit to laboratories where bench space is at a premium.

127 e methides is reported using inexpensive and bench stable AgSCF(3) as a nucleophilic trifluoromethylt

128 e, thienyl di-MIDA boronate esters represent bench stable and low toxicity alternatives to highly tox

129 ed by electrophilic C-H borylation producing bench stable crystalline solids in good yield and excell

130 se of benzimidazolium hydrogen carbonates as bench stable solid precursors for the preparation of NHC

131 formation developed herein utilizes entirely bench stable starting materials, including organotrifluo

132 hesis of azetidine-3-amines, starting from a bench stable, commercial material is presented.

133 Alkyl oxalates are new bench-stable alcohol-activating groups for radical gener

134 A variety of novel, bench-stable alkenyl gem-diboronate esters are synthesiz

135 Thereby, we explore a class of bench-stable allylboronates and fine-tune their reactivi

136 of aldehydes and amines through the use of a bench-stable allyldioxaborolane.

137 alyzed generation of aryl electrophiles from bench-stable amides with potential applications for a br

138 , which is promoted by a catalytic amount of bench-stable benziodoxole at ambient temperature.

139 iquely reactive Bi(V) arylating agent from a bench-stable Bi(III) precursor via telescoped B-to-Bi tr

140 y-MIDA-boronate was previously shown to be a bench-stable boron-containing building block for the syn

141 ethyl)phenyl)boronic acid as a highly active bench-stable catalyst.

142 The bench-stable cationic bis(sigma-B-H) aminoborane complex

143 Alkyl chlorides are bench-stable chemical feedstocks that remain among the m

144 romides as well as allylated indoles using a bench-stable Co(III) catalyst.

145 nation of nitriles to primary amines using a bench-stable cobalt precatalyst under 4 atm of H2 is rep

146 The design and a gram-scale synthesis of a bench-stable cyclohexa-1,4-diene-based surrogate of gase

147 A modular and bench-stable diazaphospholane ligand enables highly enan

148 cially available aluminum hydride DIBAL-H or bench-stable Et3 AlDABCO as the catalyst and H-Bpin as b

149 The optimal method, using the bench-stable ferroceniumboronic acid salt 1 in hexafluor

150 us methods for this transformation have used bench-stable fluorine atom sources; however, many still

151 The bench-stable fluoroborate salts of all catalysts (1F-4F)

152 red (phosphoramidite)-Cu complex and involve bench-stable gamma,gamma-disubstituted allyldiborons and

153 In this reaction, a bench-stable hydroxylamine derivative is used as the ami

154 can also easily be transformed into classic bench-stable hypervalent iodine reagents through ligand

155 Using the recently reported bench-stable imidazole-1-sulfonyl azide as diazotransfer

156 This approach yields bench-stable intermediates and avoids many of the functi

157 hydrogen approach employs a well-defined and bench-stable Mn(I) PNP pincer precatalyst, allowing benz

158 Here, we demonstrate the use of bench-stable N-H and N-alkyl oxaziridines derived from r

159 At room temperature a readily accessible bench-stable Ni(II) precatalyst is highly active and can

160 The reaction utilizes inexpensive, bench-stable Ni(OAc)(2) .4 H(2) O as a precatalyst and p

161 A representative number of bench-stable nonsymmetric diarylcarbenium tetrafluorobor

162 rifluoroborate salts, providing a variety of bench-stable organoboron building blocks for downstream

163 thiane, heteroaryl, and aryl derivatives) as bench-stable organometallics that can be readily utilize

164 nprotected thienylsulfonamides from air- and bench-stable organotrifluoroborates in the absence of a

165 ercially available, high-oxidation state and bench-stable pre-catalyst to provide a rare example of a

166 earth metal BINOLate complexes that serve as bench-stable precatalysts for Shibasaki's REMB catalysts

167 Herein we report a new bench-stable precursor that decomposes to free alkoxy ra

168 Using bench-stable precursors, an improved catalyst system wit

169 In addition, it utilizes bench-stable reagents, is operationally simple, shows hi

170 The crystalline, bench-stable siloxane transfer agent (1) is easily prepa

171 DMMN is a commercially available, bench-stable solid.

172 hines are prepared from chloroazines and are bench-stable solids.

173 These azulene sulfonium salts are bench-stable species that may be employed as pseudohalid

174 We now describe the preparation of bench-stable splice modulators by adapting carbohydrate

175 The optimized process uses a bench-stable succinimide-based Pd precatalyst (FurCat) t

176 iate is demonstrated using easily accessible bench-stable sulfinate salts.

177 (trimethylsilyl)toluenes reagents, which are bench-stable surrogates of benzyl anions and alpha-silyl

178 rom the use of readily available alkynes and bench-stable tosylhydrazones, which are easily prepared

179 A new bench-stable trifluoromethylation reagent, phenyl bromod

180 ts include the following: (i) use of a novel bench-stable Vilsmeier reagent, methoxymethylene- N, N-d

181 adium system is inexpensive, easy to handle, bench-stable, and effective in catalysis in the presence

182 MPMN is a bench-stable, carbon-bound electrophilic CN reagent that

183 This report introduces readily available, bench-stable, cheap, and benign N-acylsaccharins as aryl

184 (3))-CF(3) products in a single step using a bench-stable, commercially available trifluoromethylatio

185 ng alkyl tosylate coupling partners that are bench-stable, crystalline solids that can be prepared fr

186 E)P(mu-N (t)Bu)](2) (E = O, S, Se) which are bench-stable, H-bond receptors that can be regarded as i

187 ul sp(3)-sp(3) coupling technology that uses bench-stable, native organic functional groups, without

188 d these reagents lead to a variety of useful bench-stable, synthetic intermediates.

189 , allowing the seamless incorporation of wet-bench structural information from chemical probes and/or

190 al dysfunction and arrhythmia as reported in bench studies.

191 subjects, under assisted ventilation, and a bench study with six ventilators.

192 Real-time monitoring in the bench system indicated that high temperature and moistur

193 murine model allows researchers to actually bench test and evaluate, in preclinical studies, the eff

194 We bench-tested APP2 on ~700 3D microscopic images and foun

195 Preliminary bench testing for comparison of the Callascope camera to

196 Bench testing of the spray mechanism demonstrates that t

197 Extensive bench tests showed an in-pixel gain of 45.4 +/- 0.4 dB (

198 a durable, solar-powered air monitoring park bench that measures real-time ozone, PM2.5, and meteorol

199 latacept, have made the progression from the bench, through nonhuman primate studies and into the cli

200 It takes <12 h of bench time over a 4-d time period, and it generates up t

201 )]PF6 in >1 g quantities in less than 5 h of bench time.

202 rspective on the transition from life at the bench to an editorial career.

203 To view this Bench to Bedisde, open or download the PDF.

204 al disorders are beginning to translate from bench to bedside along the paths of neuroprotection, gen

205 over the whole translational spectrum (from 'bench to bedside and back again') with recognition that

206 ppreciate the trajectory of a biomarker from bench to bedside as well as the regulatory and other req

207 Translation of novel therapies from bench to bedside is hampered by profound disparities bet

208 or ALS patients and a substantial failure in bench to bedside translation of other potential therapie

209 ress disorder that have been developed via a bench to bedside translational model.

210 An interdisciplinary, bench to bedside translational research approach is cruc

211 research is typically used to refer both to "bench to bedside" research, in which preclinical researc

212 e extended to the clinical research setting (bench to bedside) and then to clinical practice and even

213 o has become a prototype for transition from bench to bedside, culminating in the development and cli

214 In Bench to Bedside, Kornelia Polyak peruses studies that u

215 transformational in accelerating ideas from bench to bedside, maximizing scientific discovery and im

216 nslation of new liposomal nanomedicines from bench to bedside, new cost-effective and scalable produc

217 To view this Bench to Bedside, open or download the PDF.

218 tate the application of this technology from bench to bedside.

219 -TB agents may decrease time and effort from bench to bedside.

220 ailures to translate disease treatments from bench to bedside.

221 these candidate therapeutics has moved from bench to bedside.

222 arkable speed with which these can move from bench to bedside.

223 or, which allowed moving this biomarker from bench to bedside.

224 odulator (SERM) that could move quickly from bench to bedside.

225 ominent failures to translate research from "bench to bedside." These challenges emerge on a backgrou

226 torical perspective on CRT's evolution from "bench to bedside." We also comment on the task faced by

227 Initial bench to beside translation, 2 decades ago, resulted in

228 determInantS of cardiovascular disease: from bench to beyond-Premature Acute Coronary SYndrome), a pr

229 sed to quantify the electronic coupling from bench to cell from DC to 26 GHz (with cell images at 22

230 of the time it takes to translate them from bench to clinic.

231 inhibit effective research translation from bench to clinical studies.

232 s of varying droplet size and composition on bench to enable adjuvanted vaccine delivery.

233 ion of new best practice advice from science bench to field, and ideas for future work and directions

234 t different development stages, from the lab bench to phase III clinical trials to clinical practice.

235 n order to rapidly move translation from the bench to the bedside, we believe that cooperative resear

236 at novel agents use, as they evolve from the bench to the bedside.

237 ses, providing clues for ways to connect the bench to the bedside.

238 isease (aGVHD) have been translated from the bench to the bedside.

239 erging immune monitoring technology from the bench to the bedside.

240 acial tissue engineering from the laboratory bench to the chair side.

241 challenges in translating findings from the bench to the clinic.

242 ng with efforts to move geroscience from the bench to the clinic.

243 translation of innovative concepts from the bench to the clinic.

244 e strategies translating these findings from bench to the clinic.

245 slation of renal clearable gold NPs from the bench to the clinic.

246 w of products from the producer's laboratory bench to the end users, and what can be done about it?

247 g products have already stepped from the lab-bench to the market.

248 tion of L-NVs, favouring their step from the bench to the market.

249 ent of neurotherapies must continue from the bench to their ultimate place at the bedside.

250 d biomarkers exist for either, which impedes bench-to-bedside approaches.

251 t 50 years and is now enjoying unprecedented bench-to-bedside clinical success.

252 usually understood to have evolved from the bench-to-bedside framework by which basic science transi

253 In this article, we review the bench-to-bedside journey of natalizumab, along with the

254 basic structure that underlies the original bench-to-bedside paradigm.

255 are in preclinical testing for FXS; however, bench-to-bedside plans for the clinic are severely limit

256 e, pioneers of this new drug class provide a bench-to-bedside review on preclinical validation of IDO

257 ility of biomedical studies and increase the bench-to-bedside safety and success of immunological stu

258 Here, we discuss how the tried and true bench-to-bedside strategies resulted in some spectacular

259 human health and disease, exemplified by the bench-to-bedside success of Jak inhibitors ('jakinibs')

260 Successful bench-to-bedside translation of nanomedicine relies heav

261 ights into disease pathogenesis and expedite bench-to-bedside translation of new therapeutics.

262 Challenges exist in bench-to-bedside translation, but they are not insurmoun

263 ivo and represents a promising candidate for bench-to-bedside translation.

264 e most critical bottlenecks in translational bench-to-bedside tumor biology research.

265 Through an iterative bench-to-bedside-and-back process, methods to efficientl

266 likely duration for transporting cells from bench-to-bedside.

267 g clinical trials in the field, highlighting bench-to-beside translational impact of this exciting ar

268 now given at several universities about the bench-to-newsroom career path.

269 asured by an inexpensive, portable 0.5 Tesla bench top magnetic resonance relaxometry (MRR) system wi

270 Here we present the use of high-resolution bench top-based infrared microspectroscopy to investigat

271 coffee authenticity using low-field (60MHz) bench-top (1)H NMR spectroscopy.

272 We use a commercial bench-top 1.4 T NMR spectrometer in conjunction with pai

273 atial mapping of molecular orientation using bench-top apparatus, enabling a rational approach toward

274 Herein, we report a simple, scalable, bench-top approach to covalently tethered nylon-MOF poly

275 ns for optimization of biological processes, bench-top characterization of these extended structural

276 We compared VCs constructed using the bench-top dehydration (BD), air-injection-flow (AI), pne

277 Our bench-top evaluation showed that A2D2 can release 1.9 mg

278 In bench-top experiments using an external illumination int

279 Compared to the bench-top implementations, the integrated Pound-Drever-H

280 e is equal to that obtained with traditional bench-top instrumentation.

281 Current bench-top interferometers operate in the near field with

282 ental results, when compared to conventional bench-top manual assays, reagent consumption was signifi

283 Bench-top methane production tests of shale core and pro

284 d 1000-fold fewer than those of the standard bench-top method, respectively.

285 ve emerged as a potential alternative to the bench-top optical systems in monitoring nucleic acid amp

286 CC 6803 under a sinusoidal light regime in a bench-top PBR (the Phenometrics environmental PBR [ePBR]

287 The Genisys4 is a small bench-top preclinical PET scanner designed to enable ima

288 f the Negishi coupling), including a one-pot bench-top protocol using an air- and moisture-stable bis

289 bal hydrogen taskforce in order to translate bench-top research into large-scale production of hydrog

290 mi-solvent method allows a simple, practical bench-top separation of PLGAs of varying L:G ratios.

291 In our era of bench-top sequencers and unprecedented computational pow

292 phone spectrometer is comparable to existing bench-top spectrometers in terms of stability and wavele

293 The immunoassay was performed on a bench-top system that fulfilled all the necessary charac

294 The key advantages of using this bench-top, rapid, process development tool are the flexi

295 modified spectrometer was used as an offsite bench type prototype for analyzing trace samples of API

296 in different sizes, and can be stored on the bench under noninert conditions.

297 Ls, SLM and SimVis technology simulations on bench using double-pass imaging on an artificial eye.

298 el bioinformatics approach combined with wet bench validation to identify gene networks associated wi

299 pretrial and posttrial relief rulings, and 1 bench verdict.

300 ed here, which involves approximately 4 d of bench work, is optimized for the study of mammalian cell