ライフサイエンスコーパス: beneficial effect of

1 eters in male rats, thereby proving that the beneficial effects of 17alpha-E2 are not limited to mice

2 zed mice via the GPER agonist G-1 mimics the beneficial effects of 17beta-estradiol (E(2)) on hippoca

3 and physiological mechanisms underlying the beneficial effects of 5-PAHSA and its relation to insuli

4 This study shows a 2-year beneficial effect of a program of rehabilitation mainten

5 ts.In this study, we sought to determine the beneficial effects of a bioavailable isoflavone and prob

6 Although previous studies demonstrated beneficial effects of a high-K(+) diet (HKD) on cardiore

7 ese exploratory metabolomics results support beneficial effects of a low-glycemic load dietary patter

8 Our results demonstrate that the beneficial effects of a LP diet on glucose homeostasis,

9 report here the remarkable and non-catalytic beneficial effects of a Ni(II) ion binding to a Si|PNP t

10 of this study was to investigate whether the beneficial effects of a novel mimetic of FGF21 in the LD

11 To determine whether the beneficial effects of acetazolamide (ACZ) in improving v

12 ypertension Treatment Trial (IIHTT) reported beneficial effects of acetazolamide in patients with mil

13 cture of the cellular actions underlying the beneficial effects of ACh on attention and working memor

14 Identifying the molecular targets for the beneficial effects of active small-molecule compounds si

15 Collectively, our findings suggest that the beneficial effects of acute aerobic exercise on inhibito

16 ly attenuated by C5 inhibition alone, with a beneficial effect of adding a CD14 inhibitor to attenuat

17 These studies suggested short-term beneficial effects of ADHD medication on several behavio

18 after initial periodontal treatment, without beneficial effect of adjunctive PAD.

19 ssive and negative symptoms) suggests small, beneficial effects of adjunctive antidepressants.

20 The beneficial effects of administering omalizumab on reduci

21 Our data suggest that the beneficial effects of afucosylated biologicals for clini

22 rtension management should also consider the beneficial effect of AHM on the risk for dementia.

23 These effects might be responsible for the beneficial effects of albumin therapy on outcomes of pat

24 These data suggest a dual beneficial effect of AM80, targeting both Tfh and Th17 c

25 using accelerometry have not demonstrated a beneficial effect of analgesic therapy; this is despite

26 LSK cells by ANG-(1-7) in diabetes, and the beneficial effects of ANG-(1-7) were prevented by fasudi

27 ngiotensin subtype 2 receptors abolished the beneficial effects of angiotensin type 1 receptor blocke

28 stmenopausal women, indicate that there is a beneficial effect of animal and dairy protein intakes on

29 Most clinical studies have shown no beneficial effect of anti-diabetic agents and statins on

30 psychosis, our findings reflect the possible beneficial effects of antidepressant treatment on an eme

31 Although the beneficial effects of antiretroviral (ARV) therapy for p

32 The beneficial effects of apixaban vs warfarin on rates of s

33 regulation, which could help to explain the beneficial effects of arts interventions reducing sympto

34 The beneficial effect of astrocyte-specific MGL-deficiency i

35 se heart by conditional transgenesis had the beneficial effect of augmenting mCa(2+) clearance, preve

36 challenge the well-known beneficial effect of autophagy in promoting longevity.

37 Zhou et al. challenge the well-known beneficial effect of autophagy in promoting longevity.

38 Recently, we have demonstrated beneficial effects of autophagy-activating digitalislike

39 A beneficial effect of azithromycin treatment on morbidity

40 This beneficial effect of B2 receptor blockade is rapidly rea

41 The beneficial effects of BAR501 were lost in Il-10(-/-) mic

42 Exercise seems to enhance the beneficial effect of bariatric (Roux-en-Y gastric bypass

43 The observed beneficial effects of BCG on the in-hospital mortality r

44 We report that the beneficial effect of BDPP on memory in SD is attenuated

45 ht into biological mechanisms underlying the beneficial effect of being physically active on cardiome

46 oquine (50 mg kg(-1) day(-1) ) abolishes the beneficial effects of beta(2) -adrenoceptor activation o

47 muscle-specific deletion of ATG7 blunts the beneficial effects of beta(2) -adrenoceptor on skeletal

48 Cs via CADM1 and Kit inhibit the potentially beneficial effects of beta2-AR agonists on these cells v

49 sts a molecular mechanism that underlies the beneficial effect of Bis-T-23 on podocyte physiology.

50 on in patients with ICM, suggesting that the beneficial effects of BMC application on LV remodeling a

51 rnative strategies are needed to harness the beneficial effects of BMP signaling in CKD.

52 ia were identified as the main target of the beneficial effect of both butyrate-based compounds in re

53 Moreover, CMBK was required to allow beneficial effects of both nitric oxide-sensitive guanyl

54 terest in the mechanisms responsible for the beneficial effects of breast-feeding on infant health ha

55 These findings suggest potential beneficial effects of BRJ supplementation in pregnancy,

56 upra-additive, the dominant (and potentially beneficial) effect of budesonide on formoterol-induced t

57 e or absence of myocardial viability and the beneficial effect of CABG plus medical therapy over medi

58 tory studies have failed to demonstrate any "beneficial" effects of cannabinoid agonists in individua

59 in vitro and in vivo, as demonstrated by the beneficial effect of Cavbeta antisense and gabapentin in

60 The beneficial effects of CBD on inhibitory neurotransmissio

61 mal clodronate resulted in a reversal of the beneficial effects of CD19-DE, suggesting an important r

62 rdiomyocytes mediates, at least in part, the beneficial effects of cell-based therapy in a post-MI la

63 aken together, our findings do not support a beneficial effect of chronic canola oil consumption on t

64 unoexpression, reinforcing the idea that the beneficial effect of cimetidine in PD may be due to redu

65 potential investigations of the efficacy and beneficial effects of CL3 and other promising compounds

66 inary efficacy results suggest a potentially beneficial effect of clazakizumab on ABMR activity and p

67 Whilst the beneficial effects of CNS stimulants have been mainly re

68 Beneficial effects of CO2 on photosynthetic organisms wi

69 The beneficial effect of cobalt substitution on the redox pr

70 ugh there is mounting evidence demonstrating beneficial effects of community health workers (CHWs), f

71 ssue destruction and simultaneously preserve beneficial effects of complement in areas of proliferati

72 The beneficial effects of conditional BDNF production and lo

73 creening period, which was consistent with a beneficial effect of containment efforts.

74 l end points, although 1 trial supported the beneficial effect of continuous positive airway pressure

75 sensorineural deafness, and demonstrated the beneficial effect of CoQ for maintenace of kidney functi

76 The beneficial effect of coronary CTA on outcomes is consist

77 These results suggest that beneficial effects of cortical gamma oscillations on Alz

78 In MADIT-CRT, we show a beneficial effect of CRT-D in patients without LBBB subs

79 othelial Fli1, which may help to explain the beneficial effect of cyclophosphamide on SSc vasculopath

80 Such decrease suggests that the beneficial effect of D-serine adjuvant therapy previousl

81 approaches should allow optimization of the beneficial effects of D1R stimulation in the dlPFC that

82 nalysis indicated a strongly significant and beneficial effect of DBS on TS symptoms, trait anxiety,

83 proximately 400%; p < 0.05), demonstrating a beneficial effect of DBS.

84 , and a previous feasibility study indicated beneficial effects of deep transcranial magnetic stimula

85 y a switch to permanent DST could negate any beneficial effects of delaying school start times.

86 tion level, there is growing evidence of the beneficial effects of dietary flavonoids on health.

87 Given the beneficial effects of dietary nitrate supplementation to

88 The beneficial effect of diluting tainted meat was demonstra

89 The beneficial effect of DMF treatment in Nrf2(-/-) and WT m

90 ollectively, preclinical results demonstrate beneficial effects of DMF on key molecular pathways cont

91 Our findings confirm the beneficial effects of doxycycline on ultrastructural pro

92 As such, the beneficial effects of DR on learning can be attributed t

93 The E2/ND/G platform maximized the beneficial effects of E2 through its extended release wi

94 rovide a causal explanation for the observed beneficial effects of early enteral feeding after major

95 ting the mechanisms of action underlying the beneficial effects of EC.

96 e.SIGNIFICANCE STATEMENT Our study reveals a beneficial effect of Emapunil on dopaminergic neuron sur

97 In this extended follow-up trial, the beneficial effect of endovascular treatment on functiona

98 The beneficial effects of endurance training on microvascula

99 The beneficial effect of enhancing cardiac FAO in HFD-induce

100 l, is lost upon long-term ADT, to obtain the beneficial effects of ERbeta1 on AKT signaling, an ERbet

101 order to evaluate both, the toxicity and the beneficial effect of essential elements.

102 e uterus and breast tissues and to allow the beneficial effects of estrogen in other estrogen-target

103 his study aimed to investigate the potential beneficial effects of estrogen on nigrostriatal dopamine

104 The beneficial effects of exchanging the removable component

105 r, the requirement of Fndc5 in mediating the beneficial effect of exercise remains to be determined.

106 Additionally, whether the beneficial effects of exercise can be reproduced using p

107 FNDC5/irisin is an important mediator of the beneficial effects of exercise in AD models, our finding

108 derstanding of the mechanisms underlying the beneficial effects of exercise in people with multiple s

109 ines multiple signals that contribute to the beneficial effects of exercise on cardiometabolic health

110 ; however, in contrast to HDC(-/-) mice, the beneficial effects of exogenous histamine injections wer

111 adaptive in HF, and limited data demonstrate beneficial effects of exogenous ketone therapy in studie

112 Moreover, the beneficial effects of experience were specific to cruisi

113 The beneficial effects of FAAH inhibition on fear extinction

114 hemR23 enhanced disease progression, and the beneficial effects of Fat-1(tg) were abolished in the ab

115 mptomatic 3K males, and demonstrate that the beneficial effects of female sex on PD-like neuropatholo

116 To assess the metabolically beneficial effects of fenugreek (Trigonella foenum-graec

117 hormone is based on the documented metabolic beneficial effects of FGF21, which include weight loss a

118 The beneficial effects of fixed-dose ferric citrate coordina

119 Available evidence supports a beneficial effect of flavan-3-ol intake on cardiometabol

120 far the most important way of delivering the beneficial effect of fluoride worldwide.

121 This study highlights the potential beneficial effects of food polyphenols as a nutritional

122 led membrane receptor TGR5 that demonstrated beneficial effects of FXR and TGR5 activation in the kid

123 By contrast, recent work has highlighted the beneficial effects of Galphas-coupled GPCRs on reducing

124 lating GH and IGFBP-2 levels may mediate the beneficial effects of gastric sleeve surgery in improvin

125 ceptor alpha in adipocytes recapitulates the beneficial effects of global IL10 deletion, and that loc

126 Several studies reported the beneficial effects of globus pallidus internus deep brai

127 These results are surprising because of the beneficial effects of GLP-1R analogs reported in experim

128 insights into mechanisms responsible for the beneficial effect of glycolysis induction during the rec

129 Subgroup analysis revealed a significant beneficial effect of GO in female, younger (<= 70 years)

130 The beneficial effects of heightened autophagy from Becn1(F1

131 and there have been anecdotal reports of the beneficial effects of helminths in CD patients.

132 nder acidified conditions, notwithstanding a beneficial effect of high CO2 Acidification resulted in

133 owing that under fast growth conditions, the beneficial effect of high CO2 on Trichodesmium is overwh

134 vel biological pathways that may mediate the beneficial effects of high educational attainment on ada

135 Beneficial effects of high-density lipoproteins (HDL) se

136 ioning 1-year post-transplant, but potential beneficial effects of HMPO(2) were suggested by analysis

137 y, this is the first study demonstrating the beneficial effects of HOPE on the immune response follow

138 probably a part of mechanisms leading to the beneficial effects of HT.

139 echanism(s) that explain various other known beneficial effects of hydralazine.

140 d molecular mechanisms that may underlie the beneficial effects of IIS inhibition in the adipose tiss

141 ST2 KO diminished the beneficial effects of IL-4 after ICH.

142 scular junctions (NMJs), suggesting that the beneficial effects of iMuSCs may not be restricted to ce

143 ular and neural mechanisms that underlie the beneficial effects of inflammation on social behaviour d

144 The current results support the beneficial effects of ingestion of avocado prior to subm

145 on of insect pollination, and highlights the beneficial effects of insect pollination early in the se

146 derly patients has led to questioning of the beneficial effect of intensive care unit (ICU) admission

147 This adds to the list of beneficial effects of intensive training, because hypert

148 ociated with metabolic memory, the prolonged beneficial effects of intensive vs. conventional therapy

149 Since leptin regulates inflammation, the beneficial effects of interleukin-10 (IL-10) were furthe

150 to ERC and incomplete biliary drainage, the beneficial effect of intraductal antibiotic prophylaxis

151 The beneficial effects of IRS2(5A) on beta-cell proliferatio

152 p, reflecting cellular damage, confirmed the beneficial effect of IVDV on the extraction yield.

153 vivo knockdown approach we demonstrated that beneficial effects of IVIG were mediated, at least partl

154 Clinically beneficial effects of KOR agonists (e.g., analgesia) are

155 t lymphocytes are critical for mediating the beneficial effects of L. reuteri on bone density.

156 hich play an important role in mediating the beneficial effects of L. reuteri on bone density.

157 and the role of lymphocytes in mediating the beneficial effects of L. reuteri on bone health in male

158 A beneficial effect of lenalidomide maintenance therapy on

159 These beneficial effects of leptin involve restoration of acti

160 Controversy exists regarding the adverse and beneficial effects of leptin on the heart We analysed th

161 No beneficial effects of levothyroxine were seen on seconda

162 ecent research has highlighted the potential beneficial effects of lifestyle and risk factor manageme

163 The beneficial effect of LIP ultrasound may be partly induce

164 a child during breastfeeding may weaken the beneficial effects of long breastfeeding duration.

165 This study confirms the beneficial effects of long-term exogenous galactosylcera

166 The beneficial effects of long-term oral administration of X

167 olecular mediator of hormesis, a paradoxical beneficial effect of low- or moderate-level stresses in

168 e taking conjugated equine estrogens and the beneficial effect of low-dose estrogen treatment of pati

169 n long-run reproductive success reflects the beneficial effects of lower fecundity on various measure

170 bidities and preserved autonomy supports the beneficial effects of lowering blood pressure in older h

171 n suggested as the major determinant for the beneficial effects of lung-protective ventilation.

172 sulin signaling pathway could dissociate the beneficial effects of LXR on cholesterol efflux, inflamm

173 This review focuses on the beneficial effects of MCs on tissue homeostasis and elim

174 provide conclusive evidence with regard to a beneficial effect of medical therapy in adults with syst

175 the change in thickness, suggesting that the beneficial effects of medication on symptom severity wer

176 owever, the molecular basis underlying these beneficial effects of meditation on human health still r

177 Our data not only highlight the beneficial effect of membrane TNF on T reg cell numbers

178 y suggest the presence of weight-independent beneficial effects of metabolic surgery on MACE and surv

179 Importantly, the beneficial effects of metallothionein blockade on muscle

180 ro-inflammatory signaling, but maintains the beneficial effects of microglia.

181 In this model, there was a consistent beneficial effect of midostaurin across ELN risk groups.

182 We found a beneficial effect of mineralocorticoids on survival, blo

183 atory or antimicrobial action is the primary beneficial effect of minocycline in hypertension.

184 f other factors may also be required for the beneficial effects of miR-33, and currently available ap

185 Therefore, the data show the beneficial effect of MitoQ in the metabolic dysfunction

186 C alpha2 and D1 receptors contributed to the beneficial effects of MPH across both cognitive tasks.

187 s (MSC-Ex) instead of MSCs could augment the beneficial effects of MSC therapy by overcoming the low

188 ential mechanisms that underpin the reported beneficial effects of MSC therapy in the context of live

189 Many beneficial effects of MSCs are paracrine, dependent on e

190 However, the mechanisms underlying the beneficial effect of Mt transfer are unclear and likely

191 Available evidence suggests beneficial effects of multidisciplinary interventions in

192 These results help to establish the beneficial effects of multimodal intervention and identi

193 full-term newborns, providing evidence for a beneficial effect of music on the preterm brain.

194 e two factors partially offset the perceived beneficial effects of N addition on SOC storage in tropi

195 We corroborated beneficial effects of n-3 PUFAs on pulmonary function.

196 iptional reprogramming may contribute to the beneficial effects of n3 PUFAs on EtOH-induced intestina

197 Beneficial effects of NaHS were blocked by Glib.

198 These beneficial effects of neuron-derived E2 appear to be due

199 conditions, potentially contributing to the beneficial effects of NO2(-) on mitochondrial metabolism

200 Seven of the 27 trials reported beneficial effects of noninvasive ventilation.

201 However, we did not observe a beneficial effect of novel environment exploration in ty

202 ies, and human clinical trials have reported beneficial effects of nut consumption on various health

203 sed two different rat models to evaluate the beneficial effects of O-GlcNAc stimulation at the early

204 The beneficial effects of omega-3 polyunsaturated fatty acid

205 This meta-analysis revealed no beneficial effect of omentoplasty on presacral abscess f

206 The beneficial effects of OSK-induced reprogramming in axon

207 inician-rated PTSD symptom severity did show beneficial effects of oxytocin.

208 regivers, and review evidence supporting the beneficial effects of palliative care on patient coping

209 The beneficial effects of parasympathetic stimulation have b

210 Various beneficial effects of peptides - notably those produced

211 nding prompted us to investigate whether the beneficial effect of Perk deficiency on myelination coul

212 The beneficial effects of phenotypic variability are stronge

213 vior and physical inactivity, as well as the beneficial effects of physical activity /ET and cardiore

214 ich may reduce the abundance, diversity, and beneficial effects of plant endophytic fungal communitie

215 Studies have found beneficial effects of plant-based diets on weight.

216 sidered as the current data do not support a beneficial effect of PLEX and (2) caution on the early u

217 encing (small interfering RNA) abolished the beneficial effects of PlGF inhibition on EC barrier func

218 The beneficial effects of preoperative arginine-enriched die

219 he two depth cues resulted in cancelling the beneficial effect of presenting items at a closer depth

220 Here, we investigated the beneficial effects of preventive intranasal treatment wi

221 Despite evidence for the beneficial effects of probiotics and low-fat dairy produ

222 ro.A few clinical trials have also shown the beneficial effects of probiotics in reducing oral, vagin

223 ed decorin expression, which may explain the beneficial effects of PTH2R signaling on healing.

224 In kidneys, the beneficial effect of RA has been reported in multiple di

225 Critically, however, we show that the beneficial effects of rapamycin treatment on tissue agin

226 cause rapamycin systematically inhibited the beneficial effect of recombinant human IL-7.

227 We observed the beneficial effects of recombinant ACE2 when administered

228 n of complement activation may have multiple beneficial effects of reducing endothelial injury, plate

229 ed trials and observational studies found no beneficial effects of reducing SFA intake on cardiovascu

230 The beneficial effects of RelA were mediated by increased ex

231 The beneficial effects of relaxin peptide treatment were dem

232 Beneficial effects of resistance exercise on metabolic h

233 onal interventions, and drugs to augment the beneficial effects of resistance exercise.

234 to override transmitter switching blocks the beneficial effect of running on motor skill learning.

235 inical trials are needed to determine if the beneficial effects of SAAP-FWB observed in this laborato

236 ents show resistance to these therapies, the beneficial effects of selective GR modulators are now be

237 The beneficial effect of self-sperm is mediated by a sperm-s

238 The beneficial effects of self-care include improved well-be

239 GADD34 mutant mice further indicate that the beneficial effects of Sephin1 are mediated through a dir

240 The beneficial effects of several of the antimalarial drugs

241 Observations: The beneficial effect of SGLT2 inhibitors on heart failure c

242 was to determine the potential mechanisms of beneficial effects of SGLT2 inhibition in the progressio

243 In contrast to the beneficial effects of short-term therapy, extended S100A

244 cts cardiac recovery and counterbalances the beneficial effects of short-term therapy.

245 However, whether beneficial effects of sildenafil transcend onto the feta

246 The initial beneficial effects of sirolimus treatment were not obser

247 Altogether, our results highlight the beneficial effects of spermidine, or l-arginine, on gut

248 Knockdown of phb2 partially reversed beneficial effects of SPL overexpression.

249 rvational and intervention studies suggest a beneficial effect of statin use on venous thromboembolis

250 in PBMC transcriptome may help determine the beneficial effects of statin on plaque stabilization.

251 Despite extensive evidence demonstrating the beneficial effects of statins on clinical outcomes, the

252 However, it is unclear whether the beneficial effect of stimulation is a result of neuronal

253 salience network was associated with reduced beneficial effects of stimulation.

254 This study provides Class IIb evidence for beneficial effects of STN-DBS on NMS at 36-month follow-

255 r liver fat, a mechanism consistent with the beneficial effects of storing excess triglycerides in me

256 We have recently reported the beneficial effects of subnormothermic (22 degrees C) blo

257 The ultimate translational beneficial effect of such phytocompounds on AQPs in heal

258 The beneficial effect of supramolecular enzyme assembly was

259 od long-term outcomes, which demonstrate the beneficial effect of surgical revascularization.

260 The beneficial effects of sustained or lifelong (>25 years)

261 OS trial demonstrated for the first time the beneficial effects of targeting inflammation to treat ca

262 The beneficial effects of targeting senescent cells were due

263 This may be a contributing factor for the beneficial effect of TCZ on cAMR observed in this patien

264 The beneficial effect of the intervention on incident ADHF w

265 Understanding the beneficial effects of the administration of the whole pl

266 cades, regulate AP-1 function to mediate the beneficial effects of the antidepressant response.

267 In addition to demonstrating the beneficial effects of the AREDS and AREDS2 supplements o

268 the gut barrier and partly recapitulates the beneficial effects of the bacterium.

269 to nontargeted antigens, confirmed mutually beneficial effects of the combined treatment.

270 n essential sequence for preservation of the beneficial effects of the fragments that we report here

271 tients and transgenic mice together with the beneficial effects of the glucagon-like peptide-1 agonis

272 cities of the seasonings and of the probable beneficial effects of their consumption on the preventio

273 This study aims to investigate whether the beneficial effects of therapeutic hypothermia are due to

274 Animal studies have demonstrated beneficial effects of therapeutic hypothermia on myocard

275 The potential beneficial effect of therapeutics targeting colonic micr

276 While the beneficial effects of these drugs in terms of clinical a

277 the physiological mechanisms underlying the beneficial effects of these lifestyle interventions on h

278 The beneficial effects of these repopulating microglia are c

279 Our findings highlight the beneficial effects of this enriched diet on cognitive me

280 ntensive systolic BP lowering attenuated the beneficial effects of this intervention on cardiovascula

281 mimic exercise training and may underlie the beneficial effects of this metabolite on exercise and ca

282 To investigate the potential beneficial effect of TIPE2 in muscular dystrophy, we per

283 additional efforts are needed to confirm the beneficial effects of TMOP on humans.

284 The beneficial effect of TMVr compared with GDMT alone was c

285 nervous system parenchyma, recapitulates the beneficial effects of total P2X7R depletion on the socia

286 results suggest that the reportedly socially beneficial effects of traditional martial arts may be in

287 lity in the actively treated residue and the beneficial effects of treatment extend passively 20-30 c

288 The results indicate long-term beneficial effects of treatment with statins and angiote

289 transcriptome analyses it was found that the beneficial effects of TRF are mediated by circadian cloc

290 This study investigated the beneficial effects of tubastatin A (TubA), a novel speci

291 Data showed the beneficial effects of UVC on maintenance of nutraceutica

292 Beneficial effects of variability in neuronal processing

293 ensitivity is the primary contributor to the beneficial effects of VDR activation.

294 of microbial functions that may explain the beneficial effects of vermicompost on soil and plants.

295 ta-analyses of randomized trials suggested a beneficial effect of vitamin D supplementation on muscle

296 Beneficial effects of weak and noninhibiting KIR3DL1 and

297 e two molecules widen the range of potential beneficial effects of wine and pave the way toward the e

298 Therefore, the beneficial effect of xylanase on dough and bread quality

299 tivariate analysis revealed evidence for the beneficial effect of years of experience of the most sen

300 a-restored autophagic activity abrogated the beneficial effect of young plasma against liver IRI.