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2 r the WiSE-CRT system, and provided clinical benefits to a majority of patients within an otherwise "
4 st priorities, but there was usually minimal benefit to adding all three resources to an existing sys
6 nsulin function that could offer therapeutic benefit to adults with Alzheimer's disease, vascular cog
9 gest that such a service would be of greater benefit to all parties involved than present practice, w
11 corticoids can provide clinically meaningful benefits to an appreciable number of patients, emerging
14 onable information as negative predictors of benefit to anti-EGFR monoclonal antibody therapies for t
17 balance behaviors, suggesting a therapeutic benefit to balance with ASO-29 treatment at P15 despite
18 on in cumulative tumor load, suggesting most benefit to be gained by early conversion to an mTOR inhi
19 o reduce lung cancer mortality, but for this benefit to be realized by all high-risk groups, there mu
20 ly, these delays allow superior conservation benefits to be achieved, in less time than front-loading
22 ative roles of kin selection and mutualistic benefits to be disentangled is in the resolution of conf
23 biomedical research in domains in which the benefits to be had are enormous, such as genome editing,
24 and provide indications of possible clinical benefits, to be confirmed in upcoming clinical trials.
28 new antithrombotic therapy with an improved benefit to bleeding risk profile over existing antithrom
31 ile surface fluorination process brings huge benefit to both the existing lithium-ion batteries and n
37 s frame the evidence in terms of risk versus benefit to bring greater clarity to NOAC-related major b
38 , slowed proliferation, provides a selective benefit to cancer cells during chemotherapy treatment.
39 onale for the planned work, and the expected benefits to cancer research, patient and provider decisi
40 d that as with economies of scale, there are benefits to centralization of WWTPs with resource recove
42 s are significantly associated with clinical-benefit to checkpoint inhibitor (CPI) therapy (P(meta) =
44 with lead-exposure risk might confer greater benefit to children experiencing more environmental adve
48 accurately, and rapidly could be of enormous benefit to civilian national security, military applicat
49 damages, comparing portfolios optimized for benefits to climate alone or both health and climate.
50 that acidified water may provide therapeutic benefit to CLN3 Batten disease patients, and that the pH
51 portantly, seaweed farming can provide other benefits to coastlines affected by eutrophic, hypoxic, a
58 ear from 2015 to 2030 had an unweighted mean benefit to cost ratio (BCR) of more than 10.0, whereas,
63 soform switching can provide a physiological benefit to counteract environmental stress in fishes.
64 l for decreasing soil N losses but with less benefits to crop production in temperate regions than in
65 These phase 3 trial results point to little benefit to current EGFR-targeted agents in an unselected
66 immunotherapy has achieved limited clinical benefit to date in patients with pancreatic ductal adeno
67 aenorhabditis elegans and we demonstrate its benefits to diverse aging tissues, even if exercise occu
69 averted over a 3 year period; converted the benefits to dollar equivalent values using estimates of
71 Midwest region will likely have the greatest benefit to eastern North American migratory monarchs, bu
72 ns such information sharing provides fitness benefits to emitter plants, and, therefore, whether sele
73 report data that suggest there are cognitive benefits to engaging in certain types of active behavior
74 the TME is predicted to have a combinatorial benefit to enhance current immunotherapies and that Axl
76 models that migration should confer survival benefits to evolve, and thus provide empirical evidence
77 copy number variation (CNV) can provide dual benefits to evolving virus populations, including eviden
81 nnected by currents and that their potential benefits to fishing areas are presently limited, since c
83 insect agents of myiasis can be of societal benefit to forensic science and in medicine as an aid to
85 ial growth factor) therapy offers short-term benefit to GBM patients, this approach fails as the tumo
88 groups are common and are thought to provide benefits to group members via enhanced food finding and
90 toxicity and safety but limited therapeutic benefit to HCC patients, suggesting low response rate.
91 of glycoconjugate biopolymers with apparent benefits to health; therefore, they are of economic and
92 oway and colleagues, Simon Ball explains the benefits to healthcare systems and individual patients o
94 These groups were eligible for US government benefits to help them resettle, including a domestic med
95 not represented in climate models, may be of benefit to human and ecosystem health in West Africa via
96 pigallocatechin-3-gallate (EGCG)'s potential benefits to human health have been widely investigated.
107 o determine whether rituximab provides added benefit to ibrutinib, we conducted a randomized single-c
108 nces of FLS variation and provides cascading benefits to improving predictions of how climate change
110 opulation-wide IPD, and identified potential benefits to including non-conserved pneumococcal carrier
111 er for social behaviours that bestow greater benefits to inclusive fitness, such as food sharing.
114 cell reconstitution can provide considerable benefit to individuals whose immune system has been deci
115 se or sucrose in food or beverages may be of benefit to individuals, particularly those with impaired
117 for intergroup conflict is that it provides benefits to individuals within groups in the form of rep
119 g absolute rather than relative estimates of benefits to inform treatment decisions; (2) considering
121 s a patient receives, rendering considerable benefits to institutions capable of implementing more co
126 ntly, however, followers confer a net safety benefit to leaders, as prey leading others were less lik
128 ns in the western United States provide many benefits to local economies but can also cause considera
129 riod; however, it may not provide additional benefits to long-term growth and neurodevelopmental outc
131 n may contribute to long-term cardiovascular benefits to lower-income and previously underinsured pop
133 r genes, suggesting a potential evolutionary benefit to maintaining strain diversity in specific gene
136 thway enables the delivery of key diagnostic benefits to men suspected of having cancer based on clin
137 icating that these interventions can provide benefits to mental health independent of improvements in
139 agement can provide substantial conservation benefits to most reefs for fisheries and ecological func
143 nce at the behavioral level provides similar benefits to offspring and relies on shared neural mechan
144 rnal provisioning provides similar potential benefits to offspring and relies on similar brain region
145 has left unresolved the balance of risks and benefits to offspring of medication use during pregnancy
146 impact scenario that approximates the health benefits to only the child deaths averted from measles o
148 trait is favored by natural selection if the benefit to others, [Formula: see text], multiplied by re
153 with the study team and perceived secondary benefits to participation contributed to positive trial
155 e novel medicines not only bring significant benefit to patients but also represent precision tools t
156 Whether such guided therapy is of clinical benefit to patients has been a source of controversy.
157 ic shock, PPCI offered substantial mortality benefit to patients relative to the pharmaco-invasive st
158 n=202), and it provided greater net clinical benefit to patients than did considering them all to hav
159 herapeutic cytotoxic drugs provides clinical benefit to patients with advanced or metastatic colorect
162 (ARNI) therapy provided incremental survival benefit to patients with heart failure and reduced eject
166 leukemia (CLL) provides significant clinical benefit to patients, mainly by blocking adhesion of CLL
167 imitations are that future research may show benefit to patients, new drugs from older classes may sh
173 ry mechanisms of PD-L1 can bring substantial benefits to patients with cancer by improving the effica
174 es, which have provided clinical and medical benefits to patients with novel biomarkers and therapeut
175 in adults, IRD kidneys conferred no survival benefit to pediatric candidates, although they did reduc
176 real world" intervention, this may not be of benefit to people with dementia in the current climate o
182 with an adult onset of atypical KD may be of benefit to physicians of various specialties, including
185 ammes to ensure that the considerable health benefits to populations are achieved and sustained.
186 ments in the safety of surgical practice and benefits to postoperative outcomes has not been demonstr
187 toring efforts, preventing subsequent health benefits to preschool-aged children as well as certain a
188 bilical cord clamping may provide equivalent benefits to preterm infants, but without delaying resusc
189 pleiotropic adipokine, provides therapeutic benefit to prevent AngII-induced advanced AAA in a well-
190 eprocedural patency tests have thus no added benefit to prevent ischemic complications of the hand.
191 indicate that size is not the sole adaptive benefit to producing larger offspring; maturation provid
194 s, and that fluoxetine may offer therapeutic benefits to PWS patients with respiratory complications.
195 tabolic shifts that would provide an overall benefit to radiation injury and underscore the utility o
197 0 years old and older, it does not match the benefit-to-radiation risk ratio of screening mammography
199 ffects of Ionizing Radiation VII report, the benefit-to-radiation risk ratios of mammography alone, B
200 hile lower dose (300 MBq) BSGI has estimated benefit-to-radiation risk ratios well in excess of 1 for
203 s and pathogenesis, and they link phenotypic benefit to reduction of these species through PIAS1 modu
204 ne that targets all four viruses would be of benefit to regions of the world where these diseases are
206 r example in Canada during fall, there is no benefit to releasing spores at the same time every day.
212 augmentation therapy, there was a favorable benefit-to-risk profile with similar improvement demonst
213 t be uniform over time, which may affect the benefit-to-risk ratio of guideline-recommended antithrom
214 s and patients should carefully consider the benefit-to-risk ratio of olanzapine and its additional,
218 cesses by P. aeruginosa afford a significant benefit to S. maltophilia during polymicrobial infection
220 of awareness of social good and quantify the benefits to show that moderate levels are enough to achi
222 managed pollinators provide a wide range of benefits to society in terms of contributions to food se
227 n STEM are important because of the possible benefits to STEM and society that will be realized only
228 Our findings do not reveal any measurable benefits to students, indicating that an allocation of l
229 bitopertin treatment might offer only modest benefit to suboptimal responders to antipsychotics, if a
231 es define SIRL-1 as an intervention point of benefit to suppress NET formation in disease while prese
232 is needed to provide feedback with learning benefits to surgical residents in training and to assist
233 balance between the small absolute mortality benefit to surveillance for HCC and the numerically more
235 w mass cell suicide can evolve, as any small benefit to surviving clonemates can lead to this retalia
237 ther there is improved disease-free survival benefit to taking the active drug in patients with high-
238 h program has provided exceptional value and benefit to the American public through its research prog
240 e liver and brain in this model and that any benefit to the brain would be due to improved liver meta
242 hese responses evolved to provide short-term benefit to the host to ward off infection, but impact on
243 oles within the skin microbiome that provide benefit to the host, boosting multiple aspects of barrie
245 ica appears as the climatic block that would benefit to the largest extent from this intervention, en
246 pic CBDE in the United States as well as the benefit to the length of stay LCBDE+LC has over ERCP+LC.
251 Instead, our data indicate that the growth benefit to the plant (Medicago truncatula) has greater w
252 s at the onset of ripening have a subsequent benefit to the production and preservation of aroma in w
253 as the apparent lack of additional clinical benefit to the rituximab-lenalidomide doublet, further i
254 ke of mounting evidence suggesting a lack of benefit to the routine use of PACs, there has been a de-
256 inement of natural products with therapeutic benefit, to the systematic screening of molecular librar
258 nefits to the individual as well as indirect benefits to the community by curtailing transmission.
260 ative to chemical fungicides, provides broad benefits to the environment, farmers and consumers.
261 onduct epidemiologic studies to evaluate the benefits to the fetus of maternal influenza vaccination
262 helled beans, enabling significant practical benefits to the food industry for quality control purpos
264 ction, lung neutrophils do not offer obvious benefits to the host in terms of increasing anti-viral i
267 ecause vaccination typically provides direct benefits to the individual as well as indirect benefits
269 cts on its vector, with no spillover fitness benefits to the non-vector within the same feeding guild
270 : that genes can only survive if they confer benefits to the organisms that bear them, antagonistic p
274 on CI success, but instead provides adaptive benefits to the restoration of hearing after implantatio
276 ridement provides clinical and immunological benefits to the treatment of periodontitis in patients w
278 ve grandmothers provide significant survival benefits to their grandoffspring above that provided by
280 ecies, older individuals can provide fitness benefits to their groupmates through the imparting of ec
281 s that acanthocephalan parasites could bring benefits to their hosts to cope with organic pollution.
282 Although many mobile genes provide strong benefits to their hosts, the fitness consequences of the
284 ause it does not appear to confer a survival benefit to these candidates and may delay listing and de
287 associations of these genes probably confer benefits to these E. coli strains in inhabiting and/or a
289 lfadoxine-pyrimethamine provides substantial benefit to this vulnerable population, but resistance to
292 within clinical samples present a tremendous benefit to timely diagnosis and management of patients.
296 troduces the concept of no longer clinically benefiting to underscore the distinction between first e
298 mblyopia other than spectacles, there was no benefit to VA or stereoacuity from 4 or 8 weeks of treat
299 results suggest that there may also be large benefits to vaccinating previously infected individuals.
300 Accordingly, the CytoFLEX can be of great benefit to virology and EV research, and will help to ex