ライフサイエンスコーパス: benzene ring

1 tural DNA pairs by ca. 2.4 A (the width of a benzene ring).

2 ene ring when compared with a para-connected benzene ring.

3 aromatic cyclobutadiene ring and an aromatic benzene ring.

4 ding compounds with para-substituents in the benzene ring.

5 opropyl side chain attached to a substituted benzene ring.

6 the relatively high electron density of the benzene ring.

7 he presence of, and substitution within, the benzene ring.

8 two water molecules, one to each face of the benzene ring.

9 nt electroactive substituents on the central benzene ring.

10 ding to 17 involved an unusual cleavage of a benzene ring.

11 mpound were carried out in the presence of a benzene ring.

12 d methylenes as the bridging moieties to the benzene ring.

13 sed of three [18]annulenes fused at a common benzene ring.

14 of various groups to the ortho position of a benzene ring.

15 ro group being tilted above the plane of the benzene ring.

16 alpha]quinoxaline (2, U-91571) away from the benzene ring.

17 mono-, di-, tri-, or tetrafluorinated on the benzene ring.

18 nd para-chloro- or -bromo substituent on the benzene ring.

19 f an Al(II) radical addition reaction to the benzene ring.

20 rominence as bioisosteres for the ubiquitous benzene ring.

21 s graphitic regions slightly larger than the benzene ring.

22 carbocation, which subsequently alkylates a benzene ring.

23 employed to install the methyl group on the benzene ring.

24 O)6 complex bonded to the para position of a benzene ring.

25 the porphyrins are arranged around a central benzene ring.

26 s also prefer the heteroarene rings over the benzene ring.

27 excited state antiaromatic character of the benzene ring.

28 lief of excited state antiaromaticity of the benzene ring.

29 o the classical pi-facial hydrogen bond to a benzene ring.

30 lkynylphenyl)methylphosphonates containing a benzene ring.

31 ristics of a directing group attached to the benzene ring.

32 +/0), depending upon the substituents on the benzene ring.

33 en those without the entanglement of a fused benzene ring.

34 near planarity of the fused cyclopentene and benzene rings.

35 ps attached in an eta6 fashion to all of the benzene rings.

36 ound consisting of alternating thiophene and benzene rings.

37 must have at least two conventionally fused benzene rings.

38 s and triplet ground states for nine or more benzene rings.

39 roach to the synthesis of highly substituted benzene rings.

40 tate enabled by rotation of its triazole and benzene rings.

41 y, primarily through contacts of its central benzene rings.

42 uted, meta-substituted and multi-substituted benzene rings.

43 n]) nanoribbons with a length up to 16 fused benzene rings.

44 he order of 10% in the interactions with the benzene rings.

45 y for the detection of odorants that contain benzene rings.

46 tuted triangulene that consists of six fused benzene rings.

47 ally decorating functional groups on the two benzene rings.

48 rbon nanotubes that consist of n para linked benzene rings.

49 arger number of phenol groups grafted on the benzene rings.

50 ong the chains that are connected via zigzag benzene rings.

51 to proceed via the less reactive noncentral benzene rings.

52 g more than six substituents attached on the benzene rings.

53 d to an overall expansion of the pyrrole and benzene rings.

54 sisting, from end-to-end, of 18 and 24 fused benzene rings.

55 ding alanine dipeptide, carbon nanotube, and benzene rings.

56 rings as compared to the 6-fold symmetry of benzene rings.

57 as substitutes for mono- or para-substituted benzene rings(1-7).

58 ipodal receptor with a trimethylated central benzene ring (1a) showed a cone-type conformation defini

59 of adenine, both extended by the width of a benzene ring (2.4 A).

60 ochrome b(5) reductase-CB5 chains to support benzene ring 5-hydroxylation, in which the former route

61 activity, substitutions at position 4 of the benzene ring A were associated with higher transcription

62 hat noncovalent interactions with associated benzene rings (a simple model of aromatic amino acid sid

63 rongly on the molecular headgroup on the end benzene ring addressed by the tip.

64 reas a new pathway yielding oxidation of the benzene ring after the cleavage of the piperazine ring (

65 up to four coronene units connected through benzene rings along their K-regions is described by two

66 ating and electron-withdrawing groups on the benzene ring and additional substitution on the pyran ri

67 model and an archetypal example of the para-benzene ring and are shown to be robust under a weak dis

68 The compounds, which contain a benzene ring and multiple side methyl methyl groups (gal

69 ith substituents also present on the central benzene ring and show that such substituents generally h

70 This species shows pai-aromaticity in the benzene ring and sigma-aromaticity in the outer ring for

71 5 to strengthen the interaction between this benzene ring and the agonist's quaternary ammonium (QA)

72 n the charge distribution in the substituted benzene ring and the negative charge of the carboxylate

73 fragments, are formed by the fusion of three benzene rings and belong to the class of open-shell syst

74 bon allotrope with a 2D structure comprising benzene rings and carbon-carbon triple bonds, can be syn

75 exhibited a saddle-shaped structure with two benzene rings and four pyrrole rings connected via two e

76 ill interact if they are located on adjacent benzene rings and only after being separated further tha

77 electron transport properties of pi-stacked benzene rings and show that when the symmetry of the sys

78 lex with a diyne, which generates two of the benzene rings and the macrocyclic ring of the calix in a

79 of chemical structures based on two or more benzene rings and, depending on their source, can exhibi

80 merization reaction to construct the central benzene ring, and a light-mediated radical cyclization t

81 , the charged side chain is preferred on the benzene ring, and O 1 in the coumarin scaffold is essent

82 p and a small translation of the fluorinated benzene ring, and the (19)F NMR spectrum shows three res

83 e valuable as pharmaceutical bioisosteres of benzene rings, and in particular 1,3-disubstituted BCP m

84 ry activity include the dione moiety and the benzene rings, and substitution within the rings affords

85 indolin-3-one, in which a pyrrole ring and a benzene ring are connected with a double bond instead of

86 on the organic chemistry of an eta(2)-bound benzene ring are explored using the complex TpW(NO)(PMe3

87 on-withdrawing or -donor substituents in the benzene ring are higher than that of the unsubstituted p

88 However, the prevalent use of benzene rings as the backbone limits the formation of la

89 2/3/4-monosubstituted, and 3,4-disubstituted benzene rings as well as with the 2-thienyl ring in the

90 Further variations at the indole benzene ring, as well as the C-2-unsubstituted case, hav

91 arley straw adsorbent and pi* carbon atom in benzene ring attached to fluorine of levofloxacin was in

92 odel quinones with beta-carbon from the same benzene ring available for Michael addition.

93 m) in most cations is the carbon atom in the benzene ring bearing the greatest positive charge.

94 directions, along the molecular plane as the benzene ring bridges two electrodes using anchoring grou

95 n, leading to the formation of an additional benzene ring bridging two heterocyclic scaffolds.

96 y chemo- and regioselective formation of the benzene ring by a palladium-catalyzed formal [2 + 2 + 2]

97 o pentiptycene-units linked at their central benzene ring by triple bonds to a linearly conjugated ph

98 six-pi-electron N-B-N- and B-N-B-substituted benzene rings, [C(3)BN(2)H(6)](+) and [C(3)NB(2)H(6)](-)

99 t least two electron-withdrawing groups on a benzene ring can also be arylated.

100 retical studies show that the embedded bulky benzene ring can enhance endosomal escape and mRNA deliv

101 The benzene ring can further be modified through radical rea

102 l and Hyde" split personality feature of the benzene ring can likely be useful in a range of differen

103 ents on the alkynyl group and on the central benzene ring can significantly modulate the thermodynami

104 The placement of the thiophene and benzene rings can be accurately controlled to afford a l

105 d C48H24 PAH that lacks the three peripheral benzene rings cannot be transformed into C60, whereas th

106 tabolism, including three nitrogenases, five benzene ring cleavage pathways and four light harvesting

107 n almost planar geometry for the TTF and the benzene ring connected through the vinyl spacer.

108 c transformations which include instances of benzene ring contraction to cyclopentadiene or the forma

109 orine A, from a 6/6/6 xanthone precursor via benzene ring contraction.

110 to the tapered end of the capsule where four benzene rings converge.

111 of aryl rings in the linkages to the central benzene ring, coupled with the presence of only one meso

112 When only saturated clamps are used, the benzene ring current is essentially unchanged.

113 e or more cyclobutadieno clamps disrupts the benzene ring current.

114 duction of the nitrogen-oxide group into the benzene ring decreases the DeltaH(acid) by approximately

115 one of several possible central pathways of benzene ring degradation.

116 lations, or phenalenannulations, transform a benzene ring directly into a substituted pyrene by "wrap

117 Os reveals that the para substitution on the benzene ring does not affect the electron density distri

118 d attention as a bioisosteric replacement of benzene rings due to its ability to improve the physicoc

119 n formed by two planes of carboxyl group and benzene ring, enabling the promoted intersystem crossing

120 the introduction of fluorine atoms into the benzene ring enhances the acidity of the paramagnets by

121 arable to that of a NO2- or a CN-substituted benzene ring except for the unpredictable substituent ef

122 In CAP, two adjacent hydroxy groups in a benzene ring facilitate selective diamine-dihydroxy (ami

123 ructural motif of a central para-substituted benzene ring flanked by two meta-substituted rings, givi

124 n is achieved by nitrogen insertion into the benzene ring followed by oxidative carbon extrusion.

125 cid to insert aromatic nitro-groups into the benzene rings, followed by treatment with sodium borohyd

126 ffering a new surrogate for meta-substituted benzene rings for implementation in drug discovery progr

127 sted to be used as saturated bioisosteres of benzene rings for the purpose of drug discovery projects

128 e tightly capped on one side with a bridging benzene ring, forming deep, chemically accessible caviti

129 ]heptane ring, and analogue 8a, possessing a benzene ring fused to the 5,6 position, were synthesized

130 ctural formula C(33)H(15), consisting of ten benzene rings fused in a triangular fashion.

131 d corannulene to provide all its sites, five benzene rings fused to a central five-membered ring, for

132 hape-persistent ladder polymer consisting of benzene rings fused together by inflexible bridged bicyc

133 Benzene ring fusion to the parent system results in a st

134 ped coronene derivative in which the central benzene ring has been replaced by a borazine core is des

135 An aromatic benzene ring has been used to replace the pyranose of si

136 Biphenylene analogues in which one of the benzene rings has been replaced by a different (4n + 2)

137 ene-like compounds with different numbers of benzene rings have been studied, finding out a very good

138 otential as alternative cores to traditional benzene rings, heterobicyclo[2.1.1]hexanes (HBCHexs) and

139 Therefore, THF suppresses benzene ring hydrogenation, favoring a demethoxylation r

140 roxide might whiten HA-AAAs by oxidizing the benzene ring in AAAs.

141 n exceptionally deshielded protons beta to a benzene ring in C(60)H(18) and C(60)H(36) and relatively

142 all embellishments of the highly substituted benzene ring in calicheamicin gamma(1) (I).

143 delocalization of the oxygen electron to the benzene ring in phenoxides.

144 or capability, suggesting a preference for a benzene ring in the hydrophobic side chain.

145 functionalization was observed in the other benzene ring in the ortho position with respect to the c

146 Analogs 5-16, in which the benzene ring in the phenylpropyl side chain of the GBR m

147 By replacing the benzene ring in the rhodamine core with a permanently ch

148 Each additional benzene ring in the sequence fused to cyclopentadiene in

149 and a local diatropic current at the central benzene ring in two of the series, while the third serie

150 The pyridinium and benzene rings in 11 form a dihedral angle of only 3.9 de

151 hraquinone by this procedure closes four new benzene rings in a single operation to give coronene, al

152 Replacing benzene rings in arenes by thiadiazoles thereby provides

153 cements) for commonly found para-substituted benzene rings in drug design(1).

154 ilized tools for the de novo construction of benzene rings in organic synthesis.

155 bility; however, ortho- and para-substituted benzene rings in the backbone were more likely to be deg

156 s, we noticed that the angle between the two benzene rings in the locked version is significantly sma

157 increase with increasing the number of fused benzene rings in the polycyclic unit (from naphthalene t

158 onor 5 selectively reduces alkyl-substituted benzene rings in the presence of activated esters and ni

159 bond length alternation in the six-membered benzene rings, indicating aromatic delocalization of ele

160 units to a single appropriately substituted benzene ring inhibits DCvC behavior.

161 n benzene furnishes a double addition to the benzene ring instead of a C-H bond activation, producing

162 es substantially, depending on the number of benzene rings interacting with the H(2) molecules.

163 pping degree between the two HBCs (number of benzene rings involved in pai-pai interactions between t

164 chiral open-shell hydrocarbon, in which one benzene ring is fused to [5]helicene, forming a phenalen

165 the corresponding control compounds where a benzene ring is in the position of the heterocycle, high

166 thienylethene (DTE) moieties around a single benzene ring is reported.

167 ilization energy associated with the central benzene ring is, therefore, to a certain degree compensa

168 e the decarboxylation of hydroxy-substituted benzene rings is a common motif in biosynthesis, the mec

169 extended keto-enol tautomerization across a benzene ring, is described.

170 Hexacene, an acene with six benzene rings, is notable for its exceptionally small tr

171 g, and ortho-condensed arrangements of fused benzene rings-is revealed.

172 an even number of carbons (22, in six fused benzene rings), it is not possible to draw Kekule-style

173 enylene(1-3)-a molecule that consists of two benzene rings joined by a four-membered ring at its core

174 of the parent HBC and makes the constituted benzene rings less aromatic or antiaromatic.

175 a preference for ortho- and meta-substituted benzene rings linked directly to the tertiary amine of t

176 both tautomers showed that while the central benzene ring loses aromaticity on enolization, the alpha

177 electrons of Sb(3+) and the pai electrons of benzene ring (lp-pai interaction) serves as an unexpecte

178 fications such as the numbers of constituent benzene rings, methylation and hydroxylation.

179 L homologues mediate a bifurcated pathway of benzene ring modification in the xanthone intermediate,

180 and instead, double cyclopropanation of the benzene ring occurs.

181 l solvent-exposed region on the bis(sulfonyl)benzene ring of ABT-263, made accessible through regiose

182 tution in the aliphatic part and that in the benzene ring of an organic molecule can be differentiate

183 t N386 may combine to sterically exclude the benzene ring of b12 W100 from entering a proximal pocket

184 ]BA and [(2)H6]SA feeding indicated that the benzene ring of both guaiacol and veratrole is derived f

185 The benzene ring of N-benzylformamide and the carbon chains

186 that the presence of a hydroxy group on the benzene ring of PEAs resulted in deterioration of enanti

187 r-48 and the interaction of the N-H with the benzene ring of Phe-93 of the enzyme.

188 oxides make a cation-pi interaction with the benzene ring of Phe-93.

189 where "methyl-scan" was performed around the benzene ring of the 5-hydroxy-triazolobenzazepine core.

190 on-accepting substituents are present on the benzene ring of the benzaldehyde oximes or when the hydr

191 s substitutions on the nitrogen atom and the benzene ring of the BTZ nucleus.

192 introducing bulky substituted groups on the benzene ring of the calixarene host, which then greatly

193 phic bond lengths indicates that the central benzene ring of the CP3 is partially aromatic [harmonic

194 lfur atom in DMDS by the radical site in the benzene ring of the deprotonated triradical to generate

195 Introduction of a para-nitro group into the benzene ring of the diene enabled separation of the Z,E

196 a and thia analogs of L-tryptophan, with the benzene ring of the indole replaced by pyridine or thiop

197 direct contact between the pai system of the benzene ring of the molecules and the Au(111) electrode,

198 on conditions, the central and most strained benzene ring of the p-terphenyl systems was susceptible

199 tion of its arylmethyl group to the external benzene ring of the thioxanthone, thus moving away the a

200 t pulls the imidazole over the electron-rich benzene ring of the tryptophan, possibly strengthening t

201 e branched side-chain of L10 impinges on the benzene ring of Y11 so as to constrict its movement and

202 ndings demonstrate that directly linking the benzene rings of PIs with a single C-C bond is a viable

203 mide bonds and their similar groups and even benzene rings of spicy compounds were fund to be critica

204 shift to restore the aromaticity in the two benzene rings of the product.

205 possess an imidazole moiety fused within the benzene rings of the trypticene and a pyridine ring inst

206 tophanyl side chains in situations where the benzene rings of Trp have van der Waals interactions wit

207 inding is stabilized by stacking between the benzene rings of two adjacent ligands.

208 ed cycloalkane can be stabilized by fusing a benzene ring on each side, substituted with proper funct

209 n of hydroxy and methoxy substituents to the benzene ring on the phenylpropyl moiety of 1a-1d resulte

210 al calculations to explore how the fusion of benzene rings onto aromatic chameleonic units represente

211 nce of H(2)O(2), and byproducts of oxidative benzene ring-opening were detected.

212 onstraining the carbonyl group away from the benzene ring or the greater planarity that results from

213 with the NH(+) pointing to the center of the benzene ring or to the negatively charged C atoms of the

214 a new 2D COF (TFPB-COF) with six unsaturated benzene rings per repeating unit and ordered mesoporous

215 Nucleophilic substitutions of the benzene ring proceed with aromatic amines and alcohols u

216 Surprisingly, the isothiourea with a fused benzene ring provided additional points of interaction w

217 the re-orientation and interplanar shear of benzene rings, providing a two-step stiffening mechanism

218 al lineO prefers electrophilic attack on the benzene ring rather than the usual aromatic C-H activati

219 d BamBC subunits of class II BCRs accomplish benzene ring reduction at an active-site tungsten cofact

220 lved in the energetic coupling of endergonic benzene ring reduction have remained hypothetical.

221 l oxygen-sensitive enzyme that catalyzes the benzene ring reduction reaction that is the rate-limitin

222 Benzene ring reduction requires a large input of energy

223 port through an infinite chain of pi-stacked benzene rings reflects the full 6-fold symmetry of the s

224 etween the two layers), being 26, 14, and 10 benzene rings, respectively, according to the X-ray anal

225 es a donor and an acceptor from two adjacent benzene rings, respectively, which enforces globally fol

226 isomerism drives a larger mechanical change (benzene-ring rotation) in a neighbouring ion (i.e., the

227 achieves direct C-O cleavage without initial benzene ring saturation.

228 ion and excited state antiaromaticity of the benzene ring should be reflected in its photochemical re

229 ns between a pyridine ring and a substituted benzene ring show that the pyridine is comparable to tha

230 cyclic moieties as saturated bioisosteres of benzene rings signifies a compelling evolution in modern

231 have similar potencies to QXs with the same benzene ring substitution pattern but are about 10 times

232 For compounds with the same benzene ring substitution pattern, QTOs were generally 5

233 defined coronene molecules (consisting of 13 benzene rings) terminated with linker groups, bridge eac

234 ferentially add to those carbon atoms in the benzene ring that have the greatest positive charge (but

235 of the anilino group out of the plane of the benzene ring that results in a significantly increased r

236 On a substituted benzene ring the position that bears the substituent is

237 f (13)C(6)-TATB ((13)C incorporated into the benzene ring), the same experiments have been used to sh

238 transition metal to bind to two carbons of a benzene ring, the remaining four carbons are left availa

239 ached to a single, appropriately substituted benzene ring, the resulting diradical system engages in

240 ance on the electrophilicity and quantity of benzene rings, the concentration of aromatic pollutants,

241 mol(-1) strain energy and severely distorted benzene rings, this synthesis, which employs a room-temp

242 the terminal allene carbon atom to the same benzene ring, thus forcing the allene into close proximi

243 a deamination reaction at position C4 of the benzene ring to substitute the amino group with an hydro

244 rd pi-quartets or octets, enabling the outer benzene rings to adapt closed-shell singlet Clar pi-sext

245 The reduction of abundant benzene rings to scarce C(sp(3))-rich motifs is invaluab

246 somers with linear connectivity of the fused benzene rings to those with cis- or trans-bent connectiv

247 ective synthetic route for the annulation of benzene rings to various aromatic systems, including het

248 is related to the number of methyl groups on benzene rings trapped in the nanocages of the preferred

249 isubstituted alkene bearing an electron-rich benzene ring under Kikuchi conditions to give the 2-aryl

250 interesting method for the construction of a benzene ring using propargylic alcohols and 1,3-dicarbon

251 Double cyclopropanation of the benzene ring was also observed in reactions with indoles

252 benzenesulfonamides with substituents on the benzene ring was designed and synthesized.

253 ion patterns based on the positions of fused benzene rings, we uncover clear structure-property trend

254 alene ring in place of the 1,4-disubstituted benzene ring were prepared and tested for antitumor acti

255 iable substitution pattern on the peripheral benzene ring were synthesized in good to excellent yield

256 group at the 5'-position (16) on the indolic benzene ring were synthesized through Fischer indolizati

257 ctron transfer rate through a meta-connected benzene ring when compared with a para-connected benzene

258 ophenazine units are used as substitutes for benzene rings, which are the basic building block of mos

259 f organic cations leads to closer packing of benzene rings, which enhances chemical stability and cha

260 resence of the two relatively bulky adjacent benzene rings, which help to stretch the channel, and by

261 how heteroaromatic ring substitution of the benzene ring will change the odour percept of acetopheno

262 laminobenzothiazole (or -oxazole), and/or P1-benzene ring with fluorine scan of mono- or bis-fluorine

263 eld effect) of the distributed charge in the benzene ring with the negative charge of the anionic cen

264 rocycles, essentially substituting one fused benzene ring with thiophene, pyridine or pyrrole rings.

265 sults predict that sequential methylation of benzene rings with fewer than four methyl groups will pr

266 Replacement of the benzene rings with heterocyclic substituents increased t

267 The replacement of benzene rings with sp(3)-hybridized bioisosteres in drug

268 saccharides via interactions of both central benzene rings with the sugar CH groups.

269 irst examples of direct pi-stacking of carbo-benzene rings, with inter-ring distances very close to c