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1 ound in Mtb infected patients (S456>L of the beta subunit).
2 cond highly conserved His residue within the beta subunit.
3 rodimer by various isoforms of its alpha and beta subunit.
4 membrane by virtue of the membrane-embedded beta subunit.
5 ed of an alpha subunit and a heme-containing beta subunit.
6 orce takes when applied through the integrin beta-subunit.
7 to transfer PEB to the host phycobiliprotein beta-subunit.
8 ERA1), that encodes the farnesyl transferase beta-subunit.
9 e opening, with conformational change in the beta-subunit.
10 unit and a protein disulfide isomerase (PDI) beta-subunit.
11 eceptors with the reverse ratio of alpha and beta subunits.
12 ated by RNF138 and auxiliary alpha2delta and beta subunits.
13 l surface as pentamers composed of alpha and beta subunits.
14 ors (GlyRs) composed primarily of alpha1 and beta subunits.
15 (sGC) is a heterodimer composed of alpha and beta subunits.
16 ransmembrane receptors composed of alpha and beta subunits.
17 d upon depletion of other integrin alpha and beta subunits.
18 nsist of different combinations of alpha and beta subunits.
19 in are heterotrimeric complexes of alpha and beta subunits.
20 scription factor TFIIE consists of alpha and beta subunits.
21 ore-forming alpha subunit and two associated beta subunits.
22 DELSEED loop in the C-terminal domain of the beta subunits.
23 s, which occur at the catalytic sites in the beta subunits.
24 body (nb.F3) that binds auxiliary HVACC Ca(V)beta subunits.
25 pha1A subunit with auxiliary alpha2delta and beta subunits.
26 an Actinobacteria-unique insert of the RNAP beta' subunit.
27 pecifically to the coiled-coil region of the beta' subunit.
28 cate to the interface between the alpha- and beta-subunits.
29 plication that generated distinct alpha- and beta-subunits.
30 ive alpha-subunit and one or more associated beta-subunits.
31 ecies, depending on the presence of distinct beta-subunits.
32 s ablating interaction between alpha(1C) and beta-subunits, (2) flexibility-inducing polyglycine subs
33 o our knowledge, GNB3 encoding the G-protein beta subunit 3 (Gbeta3) has not previously been implicat
34 erase reporter construct containing the AChR beta-subunit 3'UTR, caused an increase in luciferase act
36 subunit) to the NDP-binding site (within the beta subunit), a distance of 51 A has to be bridged.
37 on heat exposure postautocatalysis, Psd1(ts) beta subunits accumulate in protein aggregates that are
38 ionic/quinonoid intermediate analogue in the beta-subunit active site of the PLP-requiring enzyme try
39 (Hb) tetramer dissociates into the alpha and beta subunits (alpha- and beta-Hb), which are then separ
41 g a carbohydrate-binding module (CBM) in the beta-subunit (AMPKbeta) capable of attaching AMPK to gly
43 eptors composed of one alpha subunit and one beta subunit and are involved in cellular growth, differ
44 result suggests that the ATP binding in one beta subunit and the adenosine 5'-diphosphate (ADP) rele
46 ed in Escherichia coli in the absence of the beta subunit and the protein displayed F-actin capping a
47 examining both the iron loading into the RNR beta subunit and the RNR catalytic activity in yeast mut
49 pha) form dimers with their stably expressed beta subunits and control the transcription of downstrea
50 a2 was homogenously distributed, and the two beta subunits and gamma2 showed faint immunostaining.
51 e residues on Rad decreases its affinity for beta subunits and relieves constitutive inhibition of Ca
52 ation of KCNQ1 with different accessory KCNE beta-subunits and different modulators, but also seems l
53 tase), FARSB (phenylalanine-tRNA synthetase, beta-subunit), and NPC2 (Niemann-Pick disease type C2);
54 th other binding partners, such as alpha and beta subunits, and further assemble into pentameric rece
55 oes an endoproteolytic cleavage into a large beta-subunit, and a smaller alpha-subunit, which harbors
56 ce that lack all four specialized proteasome beta-subunits, and therefore express only constitutive p
57 s into the main channel, prying the beta and beta' subunits apart and, aided by delta, dislodging DNA
58 coassembly of these alpha subunits with the beta subunit appears to occur to a lesser extent than in
62 potassium (BK) channels and their modulatory beta-subunits are able to dampen or stop excitatory stim
64 he ligand-binding pocket, and the alpha- and beta-subunits are well separated with their cytoplasmic
65 GluClR assemblies having three alpha and two beta subunits arranged in a counterclockwise beta-alpha-
66 teasome by virtue of its different catalytic beta-subunits, as well as the proteasome activator 28 re
68 CNE4, a voltage-gated potassium (Kv) channel beta subunit associated with human atrial fibrillation,
69 biophysical properties of the skeletal DHPR beta subunit beta1a Removal of the intrinsically disorde
70 th a sequence analysis showing that the AP-2 beta subunit (beta2) of higher fungi lacks a clathrin-bi
72 requires an intact rigid linker between the beta-subunit binding site in the I-II loop and the chann
73 ugh NMR and bioforce-probe analyses that the beta-subunit binds pMHC using Vbeta complementarity-dete
74 hin the hydrophobic core of individual cross-beta subunits but has a clear effect on the motions at t
75 the metal ion-dependent adhesion site in the beta-subunit can be sufficient for binding the receptors
76 roteins bind to voltage-gated Ca(2+) channel beta subunit (Cavbeta) subunits in vitro, but the necess
80 recordings, indicates that heteromeric alpha/beta subunit-containing receptors underlie both synaptic
81 nsmembrane receptors consisting of alpha and beta subunits; crucial integrins in the kidney collectin
83 initiation of separation between alpha- and beta-subunit cytoplasmic regions, headpiece extension, a
84 ive selection express specialized proteasome beta-subunits different from those expressed by all othe
88 hibitor of apoptosis) or COP (COPI coatomer, beta subunit) dsRNA silenced their target genes and caus
90 cation and characterization of ETF alpha and beta subunit encoding genes (ETFA and ETFB) and ETFDH en
91 rmline deletion in mice of potassium channel beta subunit-encoding Kcne2 (Kcne2(CS-/-) ) causes dilat
92 anched-chain alpha-ketoacid dehydrogenase E1 beta-subunit-encoding gene (NaBCKDE1B) in the trichomes
93 isolates, and deletion of the only G-protein beta-subunit-encoding gene of A. oligospora nearly aboli
94 demonstration of S-palmitoylation of a VGSC beta subunit, establishing precedence for this post-tran
95 line deletion of the KCNE2 potassium channel beta subunit exhibited NAFLD as early as postnatal day 7
96 of the interaction of this segment with the beta subunit explain the necessity for a second highly c
97 eptogenic variants and involves differential beta subunit expression of GABA(A)R populations, which p
98 The first contained a redox-active Tyr in beta subunits (F41Y), a substitution present in Hb Mequo
109 complex consisting of the atypical G protein beta subunit Gbeta5 and a regulator of G protein signali
110 nding of a TF, using the luteinizing hormone beta subunit gene (Lhb) promoter and Egr-1 as a model sy
111 ion of the geranylgeranyltransferase type I, beta subunit gene (Pggt1b), called Pggt1b(DeltaCD4) mice
112 e knocked out the mitochondrial ATP synthase beta subunit gene in the rodent malaria parasite, Plasmo
116 rin to the mitochondrion, where it binds the beta-subunit (HADHB) of the mitochondrial trifunctional
120 ic alpha subunit complexes with glycosylated beta subunit in the ER to proceed through Golgi and post
121 s regulate the hormone-specific gonadotropin beta subunits in vivo, we deleted Dicer in gonadotropes
122 or enhancing the catalytic efficiency of the beta-subunit in the absence of its binding partner.
123 -terminal region of predominantly one of the beta-subunits in the most closed of the three catalytic
124 Kv4 pore-forming subunits co-assemble with beta-subunits including KChIP2 and DPP6 and the resultan
125 effects are influenced by the type of alpha/beta subunits incorporated into the functional receptor.
126 f-chaperone refolding mechanism, whereby the beta-subunits independently refold, thereby templating t
129 ment of Nun interacts with the RNAP beta and beta' subunits inside the RNAP active site cleft as well
130 show no significant opening of the ATP-bound beta subunit; instead, we observe that mechanical energy
133 btained from molecular modeling of the alpha-beta subunit interface and suggests that in alpha3betaGl
134 he photooxidation of FnY356 within the alpha/beta subunit interface occurs within the Marcus inverted
136 ne domain with high affinity to the gamma(+)-beta(-) subunit interface site with negative energetic c
138 B3(D120N, E180G, Y302C) mutations located at beta+ subunit interfaces reduced whole cell currents by
139 GABRB3(N110D) and GABRB1(F246S) mutations at beta- subunit interfaces produced minor changes in whole
141 31 of Escherichia coli RNA polymerase (RNAP) beta subunit is a part of RNA binding domain in transcri
145 nning voltage-gated potassium (K(v)) channel beta subunit is ubiquitously expressed and essential for
147 oprecipitates with hsp60 indicating that the beta-subunit is likely a substrate for the chaperonin.
148 that the KPNB1, a key member of Karyopherin beta subunits, is highly expressed in advanced prostate
152 fold, recruiting both vFLIP and the IKKalpha/beta subunits, it has been proposed that binding of vFLI
153 Kv4.2 and Kv4.3; co-expression of cytosolic beta subunit KChIP2, which regulates Kv4 channels in car
154 transfected with cloned Kv4.3 (or Kv4.2) and beta-subunit KChIP2, NS5806 significantly increased the
158 d potassium channel that is modulated by the beta-subunit KCNE1 to generate IKs, the slow delayed rec
160 We crossed the self-infertile ATP synthase beta subunit knockout parasites with a male-deficient, s
162 ripheral glia results in accumulation of the beta subunit (LanB1), leading to distended endoplasmic r
165 amino acids near the cytoplasmic end of the beta subunit M4 (beta3Pro-415, beta3Leu-417, and beta3Th
168 As, predicted in silico to bind gonadotropin beta subunit mRNAs, were suppressed in purified gonadotr
171 y assays revealed that the half-life of AChR beta-subunit mRNAs was increased in the presence of dene
172 hosphorylation by ULK1 was dependent on AMPK beta-subunit myristoylation, metabolic stress associated
173 ne 5'-diphosphate (ADP) release from another beta subunit occur via a transient whose lifetime is ~10
174 rtially unstructured until assembly with its beta-subunit occurs and identify a major site of incompl
175 f-function mutation in atp1b1a, encoding the beta subunit of a Na,K-ATPase pump, causes edema and epi
177 gm, the signal peptide of ruminant CD18, the beta subunit of beta2 integrins, is not cleaved and henc
179 tilocus sequence analysis of gyrase B of the beta subunit of DNA topoisomerase (gyrB), and 16S rRNA a
180 of a consensus pentapeptide motif toward the beta subunit of Escherichia coli DNA polymerase III holo
183 Hepatocystin functions as the noncatalytic beta subunit of Glucosidase II, an endoplasmic reticulum
184 t serve as a structural subunit, much like a beta subunit of heteromeric nAChRs, providing only compl
185 ic mutations in AP1B1, the gene encoding the beta subunit of heterotetrameric adaptor protein 1 (AP-1
186 CYP11A1, PTGS2, EREG, and the intracellular beta subunit of human chorionic gonadotropin (hCGbeta) a
187 3)(-) regulatory T cells in vitro, such that beta subunit of IL-27 (Ebi)(-/-) (ie, IL-27-incompetent)
189 lar function for Sequence Insertion 1 in the beta subunit of RNA polymerase and significantly advance
191 for understanding how a mutation within the beta subunit of RNAP (G1249D), which is far removed from
195 consequence of the activation of the common beta subunit of the granulocyte-macrophage colony-stimul
197 , HPV11 and HPV16 directly interact with the beta subunit of the mitochondrial ATP-synthase (ATP5B),
199 ro] and c.559G>T [p.Asp187Tyr]) encoding the beta subunit of transcription factor IIE (TFIIEbeta).
201 solved, it is clear that both the alpha1 and beta subunits of DHPR are essential for this process.
202 4 (CHD4) physically interacts with alpha and beta subunits of HIF1 and HIF2 and enhances HIF-driven t
203 pin beta (CGB) genes, which encode alpha and beta subunits of human chorionic gonadotrophin (hCG), a
204 identify GNPTAB, which encodes the alpha and beta subunits of N-acetylglucosamine-1-phosphate transfe
205 two putative alpha subunits and two putative beta subunits of Rab-GGTs have been annotated in the Ara
207 t with protein kinase CK2: (a) the alpha and beta subunits of the nicotinic acetylcholine receptors w
208 ains of topoisomerase I (TopoI-CTDs) and the beta' subunit of RNA polymerase of M. smegmatis in the a
210 de of Caudovirales that encodes the beta and beta' subunits of multi-subunit RNA polymerase (RNAP), a
212 albumin, malate dehydrogenase (MDH), and the beta-subunit of ATP synthase in in-vitro protein-folding
216 ecific methyltransferase that methylates the beta-subunit of electron transfer flavoprotein (ETFbeta)
219 fluid (CSF) levels of alpha-fetoprotein and beta-subunit of human chorionic gonadotropin are used as
224 X-ray crystal structures of the unusual beta-subunit of the acyl-CoA carboxylase (YCC) responsib
226 r HEY2, which uncovered KCNIP2, encoding the beta-subunit of the channel underlying the transient out
227 ligonucleotide-mediated exon skipping of the beta-subunit of the high-affinity IgE receptor (Fcepsilo
229 based purification scheme, we identified the beta-subunit of the mitochondrially localized electron t
232 urce of latent catalytic potential using the beta-subunit of tryptophan synthase from Pyrococcus furi
233 cross-links between Psb28 and the alpha- and beta-subunits of cytochrome b559, an essential component
235 that HCV interacted with both the alpha- and beta-subunits of the mitochondrial trifunctional protein
238 dy explored the impact of the CK2 regulatory beta-subunit on platelet biogenesis and activation.
242 omposite cytokines, consisting of the common beta subunit p40 and the specific cytokine alpha subunit
246 and functional divergence of duplicated TSH beta-subunit paralogs (tshbetaa and tshbetab) in Atlanti
247 to modulating sodium and potassium currents, beta subunits play nonconducting roles as cell adhesion
248 x active Y's, a stable Y radical (Y.) in the beta subunit (position 122 in E. coli), and three transi
249 snorkeling' lysine at the TM/CT interface of beta subunits, previously proposed to regulate alphaIIbb
250 lted in profound suppression of gonadotropin-beta subunit proteins and, consequently, the heterodimer
253 stoylated and membrane-associated regulatory beta-subunits restrict nuclear localization and inhibit
254 alpha1 subunit cell surface expression with beta subunits resulting in severely reduced synaptic inh
255 tion in 241, which encodes an RNA polymerase beta subunit, revealed that without this subunit, no oth
256 opsis Rab-GGT alpha subunits RGTA1/RGTA2 and beta subunits RGTB1/RGTB2, but only RGTA1.RGTB1 and RGTA
258 Similarly, viral-mediated expression of a beta-subunit-sequestering peptide sharply curtailed beta
259 n of plasma membrane BK(Ca) channels with BK-beta subunits shapes their biophysical properties and ph
262 tion of the succinate-CoA ligase GDP-forming beta subunit (SUCLG2), which regulates succinate metabol
263 chromophores to Cys-155 of phycobiliprotein beta-subunits, suggesting that PhiCpeT may also help ass
264 alpha1(-26') and reciprocal mutations in the beta subunit suggests that this subunit remains relative
265 ially forms encounter complexes on the MoFeP beta-subunit surface en route to the ATP-activated, ET-c
266 s the protein into a large membrane-anchored beta subunit that noncovalently associates with the smal
267 rts expressing mutant Ca(V)1.2 alpha(1C) and beta subunits that can no longer be phosphorylated by pr
268 e have termed mod2B, composed of homodimeric beta subunits that contain amino acid sequences from the
269 tif that separates the enzyme into alpha and beta subunits that remain non-covalently attached and ar
270 eracts with a structural element of the RNAP beta'-subunit that we call the beta'-clamp-toe (beta'CT)
271 otential targets for regulation by auxiliary beta-subunits that are expressed together with the alpha
272 n, a heterotetramer of paralogous alpha- and beta-subunits that mediates respiratory oxygen transport
273 the alpha subunit containing the BC and the beta subunit the CT and BCCP domains, and it is believed
275 e-TCR alpha (pTalpha) subunit and a variable beta subunit, the latter of which is incorporated into t
276 receptors (nAChRs) assembled from alpha and beta subunits, the alpha9alpha10 receptor is an atypical
277 d in a groove between the integrin alpha and beta-subunits; the basic Lys or Arg side chain hydrogen
280 the Thermotoga maritima tryptophan synthase beta-subunit (TmTrpB) through multi-mutation pathways in
281 he individual contributions of the alpha and beta subunits to the fundamental process of ATP synthesi
282 chemical energy (ATP hydrolysis in the alpha/beta-subunits) to mechanical energy and torque (rotation
283 Importantly, HuR binds to endogenous AChR beta-subunit transcripts in cultured myotubes and in viv
285 synapses, by stimulus-dependent ATP synthase beta subunit translation; this increases the ratio of AT
286 activation of the alpha-subunit TrpA and the beta-subunit TrpB via a complex allosteric network.
287 set of mutations of the tryptophan synthase beta-subunit (TrpB) from Pyrococcus furiosus, which mimi
288 is a heteropentamer consisting of alpha and beta subunit types, with yet unknown subunit stoichiomet
293 of the gamma-subunit, but not the alpha- and beta-subunits, were decreased by injury, an event associ
294 present in luteinizing hormone, and a unique beta subunit, which is transcriptionally regulated by go
295 the hydrophobic interface between the cross-beta subunits, which has been previously found to be wat
297 on of class I ribonucleotide reductase (RNR) beta subunits, which self-assemble dimetal cofactors wit
298 bind into the open ATP-binding groove of the beta-subunit, which thereafter becomes tightly locked by
299 ur KCNQ1 alpha-subunits and up to four KCNE1 beta-subunits, which are thought to reside within extern