ライフサイエンスコーパス: beta-1,6-glucan

1 creased the proportion of chitin attached to beta(1-6)glucan.

2 ry chitin chains from chitin synthase III to beta(1-6)glucan.

3 and in the lateral wall, attached in part to beta(1-6)glucan.

4 the remainder attached to beta(1-3)glucan or beta(1-6)glucan.

5 nase activity was induced in the presence of beta-1,6-glucans.

6 ly implicated in cross-linking beta-1,3- and beta-1,6-glucans.

7 ailable acceptor sites for the attachment of beta-1,6-glucans.

8 eotypic receptors proliferate in response to beta-(1,6)-glucan.

9 20% chitosan, 5% beta-(1,3)-glucan, and 70% beta-(1,6)-glucan.

10 ecific interaction between the collectin and beta(1-->6)-glucan.

11 ressing stereotypic BCRs highly specific for beta-(1,6)-glucan, a major antigenic determinant of yeas

12 The former was mostly attached to beta(1-6)glucan and the latter to beta(1-3)glucan.

13 r by a decline in beta-1,3-glucan-associated beta-1, 6-glucans and, within several generations, a fiv

14 lizing the mobile matrix by associating with beta-1,6-glucan and a small fraction of beta-1,3-glucan.

15 n provides a characteristic "fingerprint" of beta-1,6-glucan and the fine structure of the oligosacch

16 3-glucans, supported by a flexible matrix of beta-1,6-glucans and additional beta-1,3-glucans.

17 In both species, caspofungin rigidifies beta-1,6-glucans and mannan sidechains and reduces water

18 ysaccharide constituents being alpha-mannan, beta-1,6 glucan, and beta-1,3 glucan.

19 Together, these studies indicate that beta-1,6 glucans are present in the P. carinii cell wall

20 beta-(1,6)-glucan binding depended on both the stereotyp

21 E6 and KRE1, two other genes involved in the beta-1,6-glucan biosynthetic pathway, disappear in the a

22 ich are large molecules composed of a linear beta-(1,6)-glucan chains with beta-(1,3)-glucosyl side c

23 wth phenotype and 75% reduction in cell wall beta-1,6-glucan, characteristic of the cwh41Deltakre1Del

24 onents of the cell wall, beta(1-->3)-glucan, beta(1-->6)-glucan, chitin, and mannoprotein are linked

25 otein incorporation, whereas the beta(1-->3)-beta(1-->6)glucan complex was synthesized at almost norm

26 t the cell cortex, the area where the chitin-beta(1-6)glucan complex is found, was greatly enhanced a

27 Finally, SP-D showed reduced binding to the beta(1-->6)-glucan-deficient kre6 yeast mutant.

28 In addition, beta-1,6-glucan dynamics are also coordinated by host en

29 Automated assembly of beta-(1,6)-glucans equipped with two alkenyl side chains

30 In addition, isolated beta-1,6 glucan fractions from Pneumocystis elicited vig

31 particular those reacting with beta-1,3 and beta-1,6 glucan (GG).

32 kre6Deltaskn1Delta contained less cell wall beta-1,6-glucan, grew slowly with an aberrant morphology

33 The beta(1-->6)-glucan has some beta(1-->3)-linked branches,

34 major fibrillar components in its cell wall, beta-1,6-glucan, has been largely neglected.

35 a gene involved in the assembly of cell wall beta-1,6-glucan, has recently been shown to be the struc

36 d that cross-reactive proteins are linked by beta 1,6-glucan in the cell wall of each non-albicans Ca

37 ge of chitin to beta(1-3)glucose branches of beta(1-6)glucan in the cell wall of budding yeast.

38 Accordingly, we sought to characterize beta-1,6 glucans in the cell wall of Pneumocystis and to

39 mline configuration reduced the affinity for beta-(1,6)-glucan, indicating that these BCRs are indeed

40 ogether, these observations demonstrate that beta(1-->6)-glucan is an important fungal ligand for SP-

41 Finally, the reducing end of beta(1-->6)-glucan is connected to the nonreducing termi

42 In the yeast cell wall, beta(1-->6)glucan is linked to both beta(1-->3)glucan an

43 s-links, we have found that chitin linked to beta(1-6)glucan is diminished in mutants of the CRH1 or

44 The polysaccharide beta-1,6-glucan is a major component of the cell wall of

45 Here, we show that beta-1,6-glucan is essential for bilayered cell wall org

46 As we point out that beta-1,6-glucan is exposed at the yeast surface and modu

47 I (Cwh41p) in the biosynthesis of cell wall beta-1,6-glucan is indirect and that dolichol-P-glucose

48 ngs on the linkage between mannoproteins and beta(1-->6)-glucan, it is concluded that the latter poly

49 er of addition in vivo is beta(1-->3)glucan, beta(1-->6)glucan, mannoprotein.

50 yeast surface and modulate immune response, beta-1,6-glucan must be considered a key factor in host-

51 es and motifs consistent with linkage to the beta-1, 6-glucan of C. albicans cell walls have provided

52 other organisms support important roles for beta-1,6 glucans, predominantly in mediating host cellul

53 rma harzianum is utilized to release all the beta-1,6-glucan present in the wall.

54 ne receptor protein than cyclic beta-(1-->3),beta-(1-->6)-glucans produced by wild-type B. japonicum.

55 For the first time, we show that beta-1,6-glucan production compensates the defect in man

56 atographic pattern of endoglucanase digested beta-1,6-glucan provides a characteristic "fingerprint"

57 eptibility in C. auris, further highlighting beta-1,6-glucan's critical role in adaptive remodeling.

58 It contains wild-type levels of cell wall beta-1,6-glucan, shows moderate underglycosylation of N-

59 ith wall remodeling, where the regulation of beta-1,6-glucan structure and chain length is a crucial

60 ion of a functional P. carinii kre6 (Pckre6) beta-1,6 glucan synthase in Pneumocystis that, when expr

61 Recently synthesized beta-1,6 glucan synthase inhibitors decreased the abilit

62 Deletion of KRE6a, which encodes beta-1,6-glucan synthase, reduces echinocandin susceptib

63 a new gene (ndvC) involved in beta-(1--> 3), beta-(1-->6)-glucan synthesis and in nodule development.

64 ate that KRE5, KRE6 and SKN1 are involved in beta-1,6-glucan synthesis, maintenance of cell wall inte

65 KRE family, which are putatively involved in beta-1,6-glucan synthesis.

66 out 100 kDa in apparent size, is attached to beta(1-->6)-glucan through a remnant of a glycosylphosph

67 whereas C. auris maintains integrity through beta-1,6-glucan upregulation.

68 on of label into cell wall mannoproteins and beta(1-->6)glucan was observed.

69 direct role of Cwh41p in the biosynthesis of beta-1,6-glucan, we constructed a double mutant, alg5Del

70 The most abundant polymer is beta-(1,6)-glucans, which are large molecules composed o

71 roteins act by transferring chitin chains to beta(1-6)glucan, with a newly observed high activity in