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1  its effector beta-Heavy Spectrin Karst, and beta-integrin.
2 raction with the membrane proximal region of beta-integrin.
3 cident with an increase in filopodial L1 and beta-integrin.
4 on of the transmembrane domains of alpha and beta integrins.
5 educed aa sequences were compared with other beta integrins.
6 y of molecules including ECM protein-binding beta integrins.
7  serine/threonine kinase that interacts with beta integrins.
8 ial binding of the nonphosphorylated form of beta-integrins.
9 nt of neutrophil PECAM-1 activates leukocyte beta-integrins.
10 ltimately mediating activation of neutrophil beta integrins, (3) regulation of endothelial calcium in
11 quence with shared similarity to other known beta integrins (44.6-61.5%).
12 partially inhibited by the inclusion of anti-beta integrin Ab or tissue inhibitor of metalloproteinas
13 ative feedback loop in which an impaired TGF-beta-integrin alpha11beta1 axis and fibroblast collapse
14 -linked kinase (ILK) directly interacts with beta integrins and phosphorylates Akt in a phosphatidyli
15  thereby preventing lysosomal degradation of beta integrins and their associated a subunits.
16 sminogen activator, and interactions between beta integrins and tissue vitronectin.
17 sis of the hemocyte glycoproteins identified beta-integrin and dominin as CvGal1 "self"-ligands.
18 stributed late in development, at which time beta-integrin and Enabled specifically associate with ac
19 e signaling proteins, Lena (leech Ena/Vasp), beta-integrin and paxillin, but not beta-catenin, phenoc
20 cted intercalated disk fragments even though beta-integrin and vinculin have been completely removed
21 llular environment through interactions with beta-integrins and actin.
22 d proteins that bind the cytoplasmic tail of beta-integrins and localize to adhesions that anchor str
23 ts characterized by impaired localization of beta-integrins and other components of focal adhesions.
24  ICAP-1 and the cytoplasmic domains of other beta integrins, and requires a conserved and functionall
25 NA-binding partners: the cytoplasmic tail of beta-integrin, and FilGAP.
26 ple defects in blood cells involving various beta integrins (beta(1), beta(2), and beta(3)) occur sim
27 munoprecipitates with at least two different beta integrins, beta 1 integrins in 293T cells and beta
28 ith structural predictions, strain increases beta-integrin binding to FLNA, whereas it causes FilGAP
29 affinity to the talin head domain and blocks beta-integrin binding to talin.
30 s missense variant within a highly conserved beta-integrin-binding domain of TLN1 segregating with fa
31 hesized that integrin-linked kinase (ILK), a beta-integrin-binding scaffolding protein and serine/thr
32                     Single gene mutations in beta integrins can account for functional defects of ind
33  the direct recruitment of proteins onto the beta integrin chain cytoplasmic domain.
34 that C3G binds to the interface of the talin-beta-integrin complex, acting as an allosteric regulator
35 es the rapid recruitment of alpha-actinin to beta-integrin complexes at the membrane, and that the re
36 naling and motility events when localized to beta-integrin-containing focal contact sites via interac
37 d an activation-independent association with beta integrin cytoplasm domain.
38 s but lacked the region proposed to bind the beta integrin cytoplasmic domain and the tyrosine kinase
39 s of amino acids conserved between different beta integrin cytoplasmic domains, we identified the try
40 rily conserved tyrosine motifs (NPxY) in the beta integrin cytoplasmic tail to phosphotyrosine-bindin
41 nside-out signaling, a process requiring the beta integrin cytoplasmic tail, we examined the effect o
42     The cytoplasmic protein, talin, binds to beta integrin cytoplasmic tails and actin filaments, hen
43 7 bound to the membrane distal NPXY motif in beta integrin cytoplasmic tails, thereby preventing lyso
44 he cytoskeletal adaptor protein talin to the beta-integrin cytoplasmic domain is a key final step in
45 nd the membrane-proximal region (MPR) in the beta-integrin cytoplasmic domain.
46 domain to membrane-proximal sequences in the beta-integrin cytoplasmic domain.
47 n direct binding of talin and kindlin to the beta-integrin cytoplasmic tail and the transmission of f
48 3 forms a ternary complex with the Talin and beta-integrin cytoplasmic tails.
49                   A phylogenetic analysis of beta integrins did not clearly resolve whether vertebrat
50                   Pactolus is similar to the beta integrins, except it lacks a functional metal ion-d
51   Scanning is critically dependent on T cell beta-integrin function, as well as myosin light chain ki
52 s did not clearly resolve whether vertebrate beta integrin genes duplicated prior to the origin of ve
53 mining loops" (SDLs) in the I-like domain of beta integrin in regulating ligand binding.
54 To delineate the role of specific members of beta integrins in stress erythropoiesis in the adult, we
55         UNC-95 is active downstream of PAT-3/beta-integrin in the assembly pathways of the muscle den
56 alpha-actinin interacts with syndecan-4 in a beta-integrin-independent manner.
57           Moreover, disruption of the talin2-beta-integrin interaction inhibits traction force genera
58 ll invasion, indicating that a strong talin2-beta-integrin interaction is required for talin2 to fulf
59 oval or blocking of Thy-1, or blocking Thy-1-beta integrin interactions, decreased mEV uptake and pre
60 herin or alpha-catenin, and muscle-expressed beta-integrin is non-autonomously required for this loca
61                      The binding of talin to beta-integrin is strengthened by PtdIns(4,5)P(2), sugges
62  and associated with the cytoplasmic tail of beta-integrin, is a complex of many proteins, including
63 al antibody (MS13) that binds to a domain of beta-integrin known to be a ligand-binding site for cell
64 key modulatory role of a binding site within beta integrins, known as the ADMIDAS domain, in controll
65 oduct shared >/=55.6% aa similarity to other beta integrin LBDs.
66                         Murine Pactolus is a beta-integrin-like molecule expressed exclusively on the
67 facilitates CvGal1-mediated cross-linking to beta-integrin, located on the hemocyte surface, leading
68           Increased expression of CD11b, the beta-integrin marker of microglia, represents microglial
69 and is required for actin reorganization and beta-integrin-mediated adhesion after TCR crosslinking.
70 a suggest that the interaction of Thy-1 with beta integrins mediates mEV uptake by lung fibroblasts,
71                       Here, we show that the beta-integrin Myospheroid (Mys) is only required during
72 on of cell adhesion molecules, including the beta-integrin myospheroid (mys), accompany this developm
73 on-blocking antibodies against other alpha(v)beta integrins or suppression of beta(8) integrin expres
74 h either Mab13 or Cytochalasin-D, to inhibit beta-integrin or actin polymerization, respectively, sig
75 egans mutant strains that do not make either beta-integrin or vinculin, we were able to determine tha
76 mutant for myospheroid, the major Drosophila beta-integrin, or doubly mutant for multiple edematous w
77 ption process and the specific role of alpha/beta integrins, osteopontin, and related extracellular m
78 ve evolved in coordinated fashion with their beta integrin partners.
79 les, the UNC-97 protein colocalizes with the beta-integrin PAT-3 to the focal adhesion-like attachmen
80                      The cytoplasmic tail of beta-integrin (PAT-3) is associated with a conserved fou
81  and prevented their association of ILK with beta-integrins, paxillin, and vinculin.
82 egrin focal adhesion (FA) complex components beta-integrin, PINCH, and integrin-linked kinase (ILK) c
83 s phenotype, and localization of myospheroid beta-integrin protein is disrupted in tendrils mutant te
84 utrophils to delay NETosis; and blocking the beta integrin receptor, alpha(M)beta(2,) abolished fibri
85          The linkage of heterodimeric (alpha/beta) integrin receptors with their extracellular matrix
86 on of Rap1 (CtsK-Rap1), which promotes talin/beta integrin recognition, yields similar osteopetrotic
87 or cell adhesion but also by double-stranded beta-integrin RNA.
88 , it is compensated by beta1- and/or another beta-integrin(s).
89 ntified signaling complexes, including alpha/beta-integrin, Semaphorin2b, PlexinB, talin, and focal a
90 ere used to amplify from Bge cDNA, a partial beta integrin sequence of 2285 bp that contained a 1971
91  general, the phylogeny of neither alpha nor beta integrins showed a close correspondence with patter
92 ts known, in other circumstances, to mediate beta integrin signaling.
93 oplasmic tyrosine motif as a key mediator of beta-integrin signals and a potential target for new the
94  disorganization of the costameric orthologs beta-integrin, Spectrin, Talin, and Vinculin, and we pre
95 hogenic signaling circuit to operate through beta-integrin stimulation, we further show how Cdc42 is
96                                          The beta integrin subunit cytoplasmic domain is essential fo
97 ding of talin to the cytoplasmic tail of the beta integrin subunit.
98 ndent on the context of the remainder of the beta integrin subunit.
99             Mutations in Dlar and the common beta-integrin subunit mys cause a failure in oocyte elon
100 al movement of cells and localization of the beta-integrin subunit, Myospheroid, which is also requir
101  to the ligand binding domain (LBD) of known beta integrin subunits and Bge cDNA.
102             Leu262 is highly conserved among beta integrin subunits and lies within an intrachain loo
103    Several changes in the coding sequence of beta integrin subunits have now been described in human
104 opmental switching between alphav-associated beta integrin subunits to sequentially express alphavbet
105 lation sites are found in the 18 alpha and 8 beta integrin subunits.
106 on-binding sites are found in both alpha and beta integrin subunits.
107 lex interacts with the cytoplasmic domain of beta-integrin subunits and is critical for integrin sign
108                  Transcription of alpha- and beta-integrin subunits is also altered in crol and EcR m
109 flexible cytoplasmic tails of the alpha- and beta-integrin subunits.
110 defective focal adhesions and reduced active beta-integrin surface levels in a cellular model of XLCN
111 MTM1 and PI3KC2beta in the control of active beta-integrin surface levels, thereby providing a molecu
112 e of talin bound to an authentic full-length beta integrin tail.
113 he cytoskeletal protein talin, an actin- and beta-integrin tail-binding protein, plays an important r
114  the talin- and kindlin-binding sites in the beta-integrin tail.
115  to SNX17, SNX31 but not SNX27 binds several beta integrin tails in early endosomes in a PI3 (phospha
116          Surprisingly, unligated integrin or beta integrin tails recruit caspase-8 to the membrane, w
117 a FERM domain, which may enable them to bind beta integrin tails.
118                         Talin interacts with beta-integrin tails and actin to control integrin activa
119 ellular and intracellular environments, with beta-integrin tails connecting to the actin cytoskeleton
120 s with acidic membrane phospholipids as well beta-integrin tails contribute to the ability of kindlin
121          Talin2 has a higher affinity toward beta-integrin tails than talin1.
122    Although F3 contains the binding site for beta-integrin tails, F0 and F1 are also required for act
123 disease, completely disrupted its binding to beta-integrin tails.
124  for talin binding between PIPKIgamma661 and beta-integrin that may regulate dynamic FA turnover.
125 e formation of a complex involving the alpha/beta integrin transmembrane helix dimer, the head domain
126           Activation of heterodimeric (alpha/beta) integrin transmembrane receptors by the 270 kDa cy
127                                       PAT-3 (beta-integrin), UNC-112 (kindlin), and PAT-4 (integrin-l
128                           On the other hand, beta-integrin/Vinculin-positive cell contacts are reinfo
129  peptide mimicking the cytoplasmic domain of beta-integrin when compared with FAK of interphase cells
130 rate that SNX31 is an endosomal regulator of beta integrins with a restricted expression pattern.

 
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