ライフサイエンスコーパス: beta-interferon

1 ines such as interleukin-6 (IL-6), IL-8, and beta interferon.

2 he expression of type I interferons, such as beta interferon.

3 contributes to HCMV-triggered expression of beta interferon.

4 -12) p40, IL-6, IL-10, cyclooxygenase-2, and beta interferon.

5 dary production of gamma interferon or alpha/beta interferon.

6 uding the induction of and response to alpha/beta interferon.

7 n UL42 is able to suppress the production of beta interferon.

8 h increased cell death or induction of alpha/beta interferons.

9 at are known to be strongly induced by alpha/beta interferons.

10 robust antiviral response when provided with beta interferon, a molecule that strongly stimulates inn

11 CRV), all NPs tested inhibited activation of beta interferon and interferon regulatory factor 3 (IRF-

12 and induces production of cytokines, such as beta interferon and interleukin 6.

13 tion because of their impaired expression of beta interferon and the induction of immunity-related GT

14 n of attack frequency (primarily with type-1 beta interferons and glatiramer acetate).

15 s currently under study or consideration are beta-interferon and synthetic anabolic hormones.

16 In contrast to beta-interferons and glatiramer acetate, the first-gener

17 alovirus (HCMV) gene expression on cytokine (beta interferon) and chemokine (RANTES, MIG, MCP-2, MIP-

18 levels of TMEV, tumor necrosis factor alpha, beta interferon, and interleukin-6 were consistently hig

19 ssion, including production of type I (alpha/beta) interferons, and are thus very susceptible to vira

20 tory tract and have suggested that alpha and beta interferons are the first cytokines recruited to co

21 okines with direct antiviral activity, alpha/beta interferons, are only minimally induced.

22 Induction of high levels of beta interferon by all viruses possessing truncations in

23 response, including the production of alpha/beta interferon, cytokines, and other proteins that rest

24 in HeLa cells after 13 passages in the alpha/beta interferon-deficient human glial cell line U118 MG.

25 ver noncytopathically within 24 h in a alpha/beta interferon-dependent manner.

26 V strains, the sensitivities to murine alpha/beta interferon did not differ appreciably between these

27 d growth in Vero cells pretreated with alpha/beta interferon, displaying an interferon-resistant phen

28 Using this model, no association between beta-interferon exposure and the hazard of disability pr

29 a (Long-Term Benefits and Adverse Effects of Beta-Interferon for Multiple Sclerosis (BeAMS) Study, 19

30 cers of transforming growth factor beta (TGF-beta), interferon gamma (IFN-gamma), and interleukin 10

31 efore and after treatment with interleukin-1 beta, interferon gamma, and tumor necrosis factor a, cyt

32 lammatory mediators (IL-12/IL-23, interferon beta, interferon gamma, CD40L) and platelet markers.

33 naling, including transforming growth factor beta, interferon gamma, insulin-like growth factor I rec

34 associated decrease in tumor necrosis factor-beta, interferon-gamma, and monocyte chemoattractant pro

35 g production of cytokines such as interferon-beta, interferon-gamma, and stimulating dendritic cells

36 ted cells that includes transcription of the beta interferon gene via activation of interferon regula

37 r 3 (IRF3), a transcription factor for alpha/beta interferon genes, and promotes its proteasomal degr

38 ARS-CoV-WT infection, induced high levels of beta interferon (IFN) mRNA accumulation and high titers

39 to how coronaviruses affect the type I alpha/beta interferon (IFN) system.

40 the autocrine and paracrine actions of alpha/beta interferon (IFN-alpha/beta) (type I), IFN-gamma (ty

41 V3000, we examined the involvement of alpha/beta interferon (IFN-alpha/beta) activity in VEE pathoge

42 hepatic induction of cytokines such as alpha/beta interferon (IFN-alpha/beta) and gamma interferon (I

43 We have previously shown that alpha/beta interferon (IFN-alpha/beta) and gamma interferon (I

44 We have previously shown that alpha/beta interferon (IFN-alpha/beta) and IFN-gamma inhibit h

45 Our results demonstrate that alpha/beta interferon (IFN-alpha/beta) and IFN-gamma receptors

46 h host innate immunity by inactivating alpha/beta interferon (IFN-alpha/beta) and IFN-gamma signaling

47 (MARV) VP40 matrix protein antagonizes alpha/beta interferon (IFN-alpha/beta) and IFN-gamma signaling

48 inhibited in a noncytopathic manner by alpha/beta interferon (IFN-alpha/beta) and IFN-gamma.

49 nfection blocks cellular production of alpha/beta interferon (IFN-alpha/beta) and the ability of cell

50 a A virus NS1 protein, a virus-encoded alpha/beta interferon (IFN-alpha/beta) antagonist, appears to

51 l protein NS1 of influenza virus is an alpha/beta interferon (IFN-alpha/beta) antagonist, both in vit

52 le disease virus (NDV) functions as an alpha/beta interferon (IFN-alpha/beta) antagonist.

53 The secreted cytokine alpha/beta interferon (IFN-alpha/beta) binds its receptor to a

54 ponse genes such as those encoding the alpha/beta interferon (IFN-alpha/beta) cytokines.

55 tein is the inhibition of synthesis of alpha/beta interferon (IFN-alpha/beta) during viral infection.

56 I, initiating downstream signaling and alpha/beta interferon (IFN-alpha/beta) expression that establi

57 n factor critical for the induction of alpha/beta interferon (IFN-alpha/beta) expression.

58 NSs protein occurred in cells lacking alpha/beta interferon (IFN-alpha/beta) genes, indicating that

59 (NS1 and NS2) inhibit the induction of alpha/beta interferon (IFN-alpha/beta) in A549 cells and human

60 r involved in the activation of type I alpha/beta interferon (IFN-alpha/beta) in response to viral in

61 A role for alpha/beta interferon (IFN-alpha/beta) in the IFN-gamma antivi

62 transgenic mice by stimuli that induce alpha/beta interferon (IFN-alpha/beta) in the liver.

63 dames strain inhibits the induction of alpha/beta interferon (IFN-alpha/beta) in vivo and in vitro an

64 The antiviral state induced by alpha/beta interferon (IFN-alpha/beta) is a powerful selective

65 Innate cytokine responses, such as alpha/beta interferon (IFN-alpha/beta) or IFN-gamma, can have

66 y during infection correlated with the alpha/beta interferon (IFN-alpha/beta) peak, and the IFN induc

67 Alpha/beta interferon (IFN-alpha/beta) produces antiviral effe

68 NDV is a potent inducer of both alpha/beta interferon (IFN-alpha/beta) production and dendriti

69 ver, in the cells having no defects in alpha/beta interferon (IFN-alpha/beta) production and signalin

70 id dendritic cells (pDCs) triggers pDC alpha/beta interferon (IFN-alpha/beta) production in a Toll-li

71 le-stranded RNA (dsRNA), inhibits host alpha/beta interferon (IFN-alpha/beta) production, and is an e

72 lock RIG-I-like receptor signaling and alpha/beta interferon (IFN-alpha/beta) production.

73 ystem (CNS), little is known about how alpha/beta interferon (IFN-alpha/beta) protects against periph

74 Alpha/beta interferon (IFN-alpha/beta) protects the host from

75 virus infection and signal through the alpha/beta interferon (IFN-alpha/beta) receptor (IFNAR) to ind

76 Surprisingly, in alpha/beta interferon (IFN-alpha/beta) receptor knockout mice,

77 n leukocyte antigens (HLA) lacking the alpha/beta interferon (IFN-alpha/beta) receptor to study respo

78 ependent on signals through the type I alpha/beta interferon (IFN-alpha/beta) receptor.

79 mice and immune-deficient mice lacking alpha/beta interferon (IFN-alpha/beta) receptors (IFNAR(-)/(-)

80 The alpha/beta interferon (IFN-alpha/beta) response is critical fo

81 hways and/or inhibited or dysregulated alpha/beta interferon (IFN-alpha/beta) response pathways.

82 rotein antagonizes the early antiviral alpha/beta interferon (IFN-alpha/beta) response.

83 interaction of coronaviruses with the alpha/beta interferon (IFN-alpha/beta) response.

84 tein that inhibits RIG-I signaling and alpha/beta interferon (IFN-alpha/beta) responses by both dsRNA

85 Alpha/beta interferon (IFN-alpha/beta) responses did not media

86 is an inhibitor of RIG-I signaling and alpha/beta interferon (IFN-alpha/beta) responses, has been imp

87 tion route, dependent upon functioning alpha/beta interferon (IFN-alpha/beta) responses.

88 onses, especially those related to the alpha/beta interferon (IFN-alpha/beta) signaling pathways and

89 degradation of STAT1 and the block in alpha/beta interferon (IFN-alpha/beta) signaling that occurs a

90 Alpha/beta interferon (IFN-alpha/beta) signaling through the I

91 The alpha/beta interferon (IFN-alpha/beta) system is the first lin

92 immune response, and in particular the alpha/beta interferon (IFN-alpha/beta) system, plays a critica

93 ine BMDCs by microarray suggested that alpha/beta interferon (IFN-alpha/beta) transcripts and numerou

94 Alpha/beta interferon (IFN-alpha/beta) triggers antiviral and

95 (IL-12), nitric oxide, NADPH oxidase, alpha/beta interferon (IFN-alpha/beta), and IFN-gamma.

96 te immune response elements, including alpha/beta interferon (IFN-alpha/beta), immunoglobulin M, gamm

97 s (cpBVDV) results in the induction of alpha/beta interferon (IFN-alpha/beta), whereas noncytopathoge

98 was previously demonstrated to inhibit alpha/beta interferon (IFN-alpha/beta)- and IFN-gamma-induced

99 The alpha/beta interferon (IFN-alpha/beta)-induced STAT signal tra

100 largely determined by the efficacy of alpha/beta interferon (IFN-alpha/beta)-mediated antiviral resp

101 e responses to infection by inhibiting alpha/beta interferon (IFN-alpha/beta)-mediated JAK-STAT signa

102 compared the genetic, pathogenic, and alpha/beta interferon (IFN-alpha/beta)-regulatory properties o

103 (moDCs), with the notable exception of alpha/beta interferon (IFN-alpha/beta).

104 critical for the biological actions of alpha/beta interferon (IFN-alpha/beta).

105 responses, including the expression of alpha/beta interferon (IFN-alpha/beta).

106 sensitive to the antiviral actions of alpha/beta interferon (IFN-alpha/beta).

107 in SCID mice; prominent among these is alpha/beta interferon (IFN-alpha/beta).

108 of tuberculosis, leads to secretion of alpha/beta interferon (IFN-alpha/beta).

109 se virus (FMDV) is highly sensitive to alpha/beta interferon (IFN-alpha/beta).

110 is associated with the suppression of alpha/beta interferon (IFN-alpha/beta).

111 was found to be due, in large part, to alpha/beta interferon (IFN-alpha/beta).

112 ibroblasts or primary astrocytes, with alpha/beta interferon (IFN-alpha/beta).

113 (wild-type [WT]) mice and mice deficient in beta interferon (IFN-beta) (BKO), antibody (muMT), IFN-g

114 receptor domain-containing adaptor-inducing beta interferon (IFN-beta) (TRIF) is critical in inducin

115 orted that HCMV attenuates the expression of beta interferon (IFN-beta) and a number of proinflammato

116 express LAT or AL gene products (dLAT2903), beta interferon (IFN-beta) and IFN-alpha RNA expression

117 ned that the extent of reovirus induction of beta interferon (IFN-beta) and IFN-beta-mediated protect

118 resulted in the more relevant production of beta interferon (IFN-beta) and IFN-lambda1 in response t

119 cells by restricting the early induction of beta interferon (IFN-beta) and interferon-stimulated gen

120 HCV infection significantly increased beta interferon (IFN-beta) and interleukin-6 (IL-6) secr

121 ytokines involved in innate immunity such as beta interferon (IFN-beta) and interleukin-6 (IL-6).

122 nal domains have similar effects on both the beta interferon (IFN-beta) and LMP1 promoters in BJAB an

123 onstrated that WNV induced the expression of beta interferon (IFN-beta) and several IFN-stimulated ge

124 The addition of antibodies to beta interferon (IFN-beta) blocked interferon-directed M

125 A neutralizing antibody against beta interferon (IFN-beta) blunted Ser(727) phosphorylat

126 CD95-mediated nonapoptotic signaling induced beta interferon (IFN-beta) expression and correlatively

127 Moreover, Cal WT inhibited beta interferon (IFN-beta) expression and replicated mor

128 n hepatoma cells inhibited poly(I.C)-induced beta interferon (IFN-beta) expression and that the HEV o

129 e viral gene 5 product, NSP1, can antagonize beta interferon (IFN-beta) expression by inducing the de

130 In contrast, RSV-induced beta interferon (IFN-beta) expression is not influenced

131 Beta interferon (IFN-beta) expression is triggered by do

132 an cytomegalovirus (HCMV) gene expression on beta interferon (IFN-beta) expression was examined.

133 as reduced by NSC95397 in favor of increased beta interferon (IFN-beta) expression, and NSC95397 was

134 immortalized human hepatocytes (IHH) induces beta interferon (IFN-beta) expression.

135 VISA, or Cardif), and inhibits MAVS-mediated beta interferon (IFN-beta) expression.

136 on regulatory factor 3 (IRF3) activation and beta interferon (IFN-beta) expression.

137 Beta interferon (IFN-beta) gene expression in response t

138 ivate transcription factors needed to induce beta interferon (IFN-beta) gene transcription.

139 nhibiting its phosphorylation and downstream beta interferon (IFN-beta) gene transcription.

140 s L is a multifunctional protein that blocks beta interferon (IFN-beta) gene transcription.

141 Beta interferon (IFN-beta) has been used in the treatmen

142 also secreted the immunomodulatory cytokine beta interferon (IFN-beta) in a largely MyD88-independen

143 ys a key role in preventing the induction of beta interferon (IFN-beta) in virus-infected cells.

144 IG-I, KSHV transcription is increased, while beta interferon (IFN-beta) induction is attenuated.

145 r sensor of RNA virus infection resulting in beta interferon (IFN-beta) induction.

146 Autocrine or paracrine signaling by beta interferon (IFN-beta) is essential for many of the

147 Nod2(-/-) mice have reduced beta interferon (IFN-beta) levels and fewer activated de

148 C to the virus and show a rapid induction of beta interferon (IFN-beta) mRNA but not IFN-alpha mRNA.

149 Beta interferon (IFN-beta) mRNA was induced in HRV1a-inf

150 pre-mRNAs, thereby inhibiting production of beta interferon (IFN-beta) mRNA.

151 processing of cellular pre-mRNAs, including beta interferon (IFN-beta) pre-mRNA.

152 s difference was greater under conditions of beta interferon (IFN-beta) pretreatment.

153 izing antibodies, we further determined that beta interferon (IFN-beta) production and secretion are

154 I West Nile virus (WNV) strain Eg101 induced beta interferon (IFN-beta) production as early as 12 h a

155 the host innate defense by interfering with beta interferon (IFN-beta) production in response to dif

156 ave strong to moderate inhibitory effects on beta interferon (IFN-beta) promoter activation.

157 ee distinct mechanisms: it directly inhibits beta interferon (IFN-beta) promoter activity, it promote

158 latory factor 3 (IRF3), or IRF7 to stimulate beta interferon (IFN-beta) promoter activity.

159 proteins also block virus activation of the beta interferon (IFN-beta) promoter and the IFN regulato

160 n was found to inhibit the activation of the beta interferon (IFN-beta) promoter induced by viral inf

161 om the simian virus 40 promoter and from the beta interferon (IFN-beta) promoter, while M proteins of

162 nger, are necessary for inhibiting the human beta interferon (IFN-beta) promoter.

163 NSs protein inhibited the activation of the beta interferon (IFN-beta) promoter.

164 While there is 1 beta interferon (IFN-beta) protein, there are 12 differe

165 , but not ANDV, was found to induce a robust beta interferon (IFN-beta) response early after infectio

166 pathogenic genotype, T953, downregulates the beta interferon (IFN-beta) response in vitro in equine e

167 virus infection that regulates the cellular beta interferon (IFN-beta) response.

168 reading frame [P(C-)], resulting in a potent beta interferon (IFN-beta) response.

169 es, vesicular stomatitis virus evoked robust beta interferon (IFN-beta) responses.

170 gue virus regulation of early, but not late, beta interferon (IFN-beta) responses.

171 navirus infection induces expression of both beta interferon (IFN-beta) RNA and protein in the infect

172 ian rhesus rotavirus (RRV) robustly triggers beta interferon (IFN-beta) secretion, resulting in an IF

173 levels of the downstream antiviral cytokine beta interferon (IFN-beta) than does wild-type virus des

174 3, an important transcriptional regulator in beta interferon (IFN-beta) transcription, fails to effec

175 reduced inhibition of activation of IRF3 and beta interferon (IFN-beta) transcription.

176 Beta interferon (IFN-beta) transcripts were induced earl

177 at the two cell types respond differently to beta interferon (IFN-beta) treatment.

178 In contrast, epithelial production of beta interferon (IFN-beta) was not inhibited.

179 ed and, in response to this, a high level of beta interferon (IFN-beta) was produced during NH/P68 in

180 All three proteins inhibit the expression of beta interferon (IFN-beta), and further examination reve

181 Poly(I.C) pretreatment upregulated beta interferon (IFN-beta), IFN-gamma, IL-1beta, and tum

182 Consistent with this finding, RSV-induced beta interferon (IFN-beta), interferon-inducible protein

183 aE3L mutant virus triggers the production of beta interferon (IFN-beta), interleukin-6 (IL-6), CCL4,

184 3alpha), and the MyD88-independent molecules beta interferon (IFN-beta), nitric oxide, and IFN-gamma-

185 tory transcription factors (IRF-3 or IRF-7), beta interferon (IFN-beta), or the receptor for type I I

186 production of type I interferons, including beta interferon (IFN-beta), which, surprisingly, promote

187 ed following L. monocytogenes infection in a beta interferon (IFN-beta)-dependent fashion.

188 nfection can overcome the establishment of a beta interferon (IFN-beta)-induced antiviral state in pr

189 cies in E3 ligase activity cannot counteract beta interferon (IFN-beta)-induced restriction of viral

190 response characterized by the expression of beta interferon (IFN-beta).

191 e synthesis of proinflammatory cytokines and beta interferon (IFN-beta).

192 hantaviruses inhibit the early induction of beta interferon (IFN-beta).

193 terleukin 1beta (IL-1beta), IL-6, IL-10, and beta interferon (IFN-beta).

194 dia infection, resulting in the synthesis of beta interferon (IFN-beta).

195 of IRF3-dependent antiviral genes, including beta interferon (IFN-beta).

196 signaling, which leads to the activation of beta interferon (IFN-beta).

197 r adventitial fibroblasts (BRAFs), levels of beta interferon (IFN-beta,) STAT1, and STAT2 transcripts

198 y a role in innate immunity, including alpha/beta interferons (IFN).

199 been reported to be a poor inducer of alpha/beta interferons (IFN-alpha/beta) and partially resistan

200 , which is essential for production of alpha/beta interferons (IFN-alpha/beta) and upregulates expres

201 The type I alpha/beta interferons (IFN-alpha/beta) are known to play an i

202 Alpha/beta interferons (IFN-alpha/beta) are not only a powerfu

203 Alpha/beta interferons (IFN-alpha/beta) are potent, endogenous

204 To define the role of alpha/beta interferons (IFN-alpha/beta) in simian immunodefici

205 Alpha/beta interferons (IFN-alpha/beta) induce potent antivira

206 Type I alpha and beta interferons (IFN-alpha/beta) limit HuNoV replicon f

207 BV X protein and apparently due to alpha and beta interferons (IFN-alpha/beta), as the effects could

208 tial virus (HRSV) is a poor inducer of alpha/beta interferons (IFN-alpha/beta).

209 l components can be potent inducers of alpha/beta interferons (IFN-alpha/beta).

210 Alpha/beta interferons (IFN-alpha/betas) are known to antagoni

211 at activate the genes that encode alpha- and beta-interferon (IFN).

212 Alpha/beta-interferon (IFN-alpha/beta) treatment improves card

213 ealed a conundrum: reovirus T3D induces more beta-interferon (IFN-beta) mRNA in cardiac myocytes, yet

214 (LCMV) induces type I interferon (alpha and beta interferon [IFN-alpha and IFN-beta]) upon infection

215 observed for other relevant proteins (alpha/beta interferon [IFN-alpha/beta] and IL-10).

216 Type I interferon (alpha/beta interferon [IFN-alpha/beta]) and type II interferon

217 sly, we showed that type I interferon (alpha/beta interferon [IFN-alpha/beta]) can inhibit foot-and-m

218 d the expression of type I interferon (alpha/beta interferon [IFN-alpha/beta]) in mouse oligodendrocy

219 ferentially induce type I interferons (alpha/beta interferon [IFN-alpha/beta]) in myeloid dendritic c

220 ated the role that type I interferons (alpha/beta interferon [IFN-alpha/beta]) might play in H5N1 pat

221 Type I interferon (alpha/beta interferon [IFN-alpha/beta]) stimulates the express

222 ice deficient in receptors for type I (alpha/beta interferon [IFN-alpha/beta]), type II (IFN-gamma),

223 IL-1, IL-6, tumor necrosis factor alpha, and beta interferon [IFN-beta]) important in the innate immu

224 r mutants' sensitivity to type I interferon (beta interferon [IFN-beta]) in restrictive cells, we not

225 AstV-1) infection induces type I interferon (beta interferon [IFN-beta]) production in differentiated

226 , macrophage inflammatory protein 1beta, and beta interferon [IFN-beta]) that can be induced through

227 tor (IL-12p40, IL-4), and interferon system (beta interferon [IFN-beta], IFN-gamma, protein Mx1 GTPas

228 e induction of type I interferons (alpha and beta interferons [IFN-alpha and -beta]) constitutes the

229 unique ability of ANDV N protein to inhibit beta interferon (IFNbeta) induction may contribute to it

230 Alpha/beta interferons (IFNs-alpha/beta) are cytokines that pl

231 Alpha/beta interferon immune defenses are essential for resist

232 e expression levels and sensitivity to alpha/beta interferon in cultured cells indicated that each mi

233 ass II (MHC-II), and cytokines such as alpha/beta interferon in immature DCs.

234 al cytokines tumor necrosis factor alpha and beta interferon in macrophages, and this induction was i

235 ptor involvement; however, the expression of beta interferon in MyD88-/- Mphi suggests involvement of

236 studies demonstrated superior efficacy over beta-interferon in reducing disability progression over

237 e recombinase under the control of the alpha/beta interferon-inducible (MX) promoter.

238 is finding, RSV-induced beta interferon (IFN-beta), interferon-inducible protein 10 (IP-10), chemokin

239 Alpha/beta interferon induction by polyinosinic-polycytidylic

240 tability of HBV CCC DNA in response to alpha/beta interferon induction was examined in HNF1alpha-null

241 plication intermediates in response to alpha/beta interferon induction.

242 ry factor 7 and inhibit virus-mediated alpha/beta interferon induction.

243 ial (IMPACT)] became the fourth study of the beta interferons (interferon-beta-1a, in this case) to d

244 or necrosis factor alpha, interleukin-6, and beta interferon is observed during rWSN NS1 R38A infecti

245 r of interferon-responsive genes, as well as beta interferon itself.

246 The sensitivity to murine alpha/beta interferon-mediated antiviral activity was previous

247 o assess the association between exposure to beta-interferon medications and disease progression amon

248 ed viral replication and increased levels of beta interferon, MMP-3, MMP-12, and TIMP-1 mRNA.

249 t, we found that coadministration of an anti-beta interferon monoclonal antibody with the plasmid DNA

250 ly, the compounds reversed the inhibition of beta interferon mRNA induction during infection, which i

251 In the latter cell line, accumulation of beta interferon mRNA occurred after infection by these N

252 oes not bind CPSF30 in vitro and causes high beta interferon mRNA production and reduced virus replic

253 production of all cellular mRNAs, including beta interferon mRNA.

254 to support the transcriptional induction of beta interferon mRNA.

255 and gB establish an antiviral state in alpha/beta interferon null cells, illustrating that primary in

256 of cytokines with antiviral activity, alpha/beta interferon, occurred too late to prevent virus repl

257 n respiratory epithelial cells and what role beta interferon played in this response.

258 cessing of all cellular pre-mRNAs, including beta interferon pre-mRNA.

259 ponsive signaling pathways that induce alpha/beta interferon production and engage intracellular immu

260 Ebola virus VP35 inhibits alpha/beta interferon production and functions as a viral poly

261 ry factor-3 (IRF-3) activation directs alpha/beta interferon production and interferon-stimulated gen

262 ring Toll-like receptor 9 and inducing alpha/beta interferon production by plasmacytoid dendritic cel

263 persisting in cells with no defects in alpha/beta interferon production or signaling.

264 navirus papainlike protease protein to block beta interferon promoter activation.

265 ed RNA-dependent activation of a transfected beta interferon promoter construct.

266 tor 3 (IRF3) and accumulation of IRF3 at the beta interferon promoter in gammaherpesvirus-infected pr

267 otein unable to inhibit the induction of the beta interferon promoter mediated by virus infection.

268 One of these HBx binding partners is beta interferon promoter stimulator 1 (IPS-1), an adapto

269 anscription, inhibits transcription from the beta interferon promoter, and promotes the proteasomal d

270 proteins prevent MDA5 from signaling to the beta interferon promoter, but the consequences of LGP2 t

271 s ability to bind to DNA and to activate the beta interferon promoter.

272 ndent reporter luciferase production via the beta interferon promoter.

273 m interferon-stimulated response elements or beta-interferon promoters in a dose-dependent manner.

274 es showed that while cells lacking the alpha/beta interferon receptor exhibited decreased levels of t

275 These results indicate that while the alpha/beta interferon receptor is needed to curb viral replica

276 However, alpha/beta interferon receptor knockout (IFNAR(-/-)) mice were

277 Infection of alpha/beta interferon receptor knockout (IFNAR(-/-)) mice with

278 ouse embryonic fibroblasts lacking the alpha/beta interferon receptor, the gamma interferon receptor,

279 In the absence of the alpha/beta interferon receptor, we observed increased viral re

280 rulence thresholds in mice lacking the alpha/beta interferon receptor.

281 SFV-RDR infection of mice lacking alpha/beta interferon receptors resulted in widespread virus d

282 erferons, cloning of human IFN-alpha and IFN-beta, interferon receptors, activities and therapeutic u

283 expression of CCAAT/enhancer-binding protein-beta, interferon regulatory factor 4, and peroxisome pro

284 rs, including CCAAT/enhancer-binding protein-beta, interferon regulatory factor 4, and peroxisome pro

285 Genetic elements including the beta-interferon scaffold attachment region (SAR) have be

286 reduced amounts of interleukin-18 and alpha/beta interferon secreted in the TLR2 KO mice.

287 SM does not directly stimulate alpha/beta interferon secretion but instead induces STAT1, an

288 ed by specific stimuli, mainly via the alpha/beta interferon signaling pathway.

289 T3D, represses one antiviral response: alpha/beta interferon signaling.

290 s-infected cells produced greater amounts of beta interferon than wild-type virus-infected cells.

291 sponse factor 3 (IRF3) activation, a lack of beta interferon transcript induction, loss of interferon

292 being sufficient to enhance HCMV-stimulated beta interferon transcription and secretion.

293 les involved in HCMV-mediated IRF3-dependent beta interferon transcription are virtually unknown.

294 approaches to investigate the association of beta-interferon treatment with delaying disability progr

295 ed by TIR domain-containing adapter-inducing beta interferon (TRIF) during establishment and reactiva

296 r (IL-1R) domain-containing adaptor-inducing beta interferon (TRIF) for signaling, but we recently re

297 , and TIR-domain-containing adaptor-inducing beta interferon (TRIF), or RIG-I/MDA5 adaptor, interfero

298 g the TIR domain-containing adaptor inducing beta interferon (TRIF).

299 tor (TIR) domain-containing adaptor-inducing beta-interferon (TRIF, also called TIR-domain-containing

300 While secreted alpha/beta interferon was required for increased expression of