ライフサイエンスコーパス: beta-ionone

1 t had no impact on other terpene alcohols or beta-ionone.

2 d dopamine receptors, and the opsin agonist, beta-ionone.

3 s identified a set of antagonists, including beta-ionone.

4 beta-ionone, 4-oxoisophorone and dihydroactinidiolide we

5 tile analysis showed a > or =50% decrease in beta-ionone (a beta-carotene-derived C13 cyclohexone) an

6 enes (alpha-ionone, beta-ionone, and dehydro-beta-ionone), a class of compounds whose reactivities wi

7 ed at the 9,10 (9',10') bonds and generating beta-ionone, although beta-cyclocitral resulting from a

8 , ATR, as well as the noncovalent binding of beta-ionone, an antagonist for G protein activation.

9 oxidation and minor quantities of 5,6-epoxy-beta-ionone and 5,6-epoxy-4-oxo-beta-apo-11-carotenal, n

10 ope dilution assay (SIDA): beta-damascenone, beta-ionone and alpha-ionone.

11 to uninfected controls, and generated trans-beta-ionone and beta-cyclocitral, which were attributed

12 (E)-beta-ionone and beta-ocimene, which are important compou

13 ceeded with extremely high concentrations of beta-ionone and binding did not alter the structure of r

14 alcohols, volatile phenols and pantolactone; beta-ionone and herbaceous nuances were in higher propor

15 f detection in both concentration (200 pM of beta-ionone) and in molecular weight of VOCs (100 g/mol

16 des, while diethyl succinate, decanoic acid, beta-ionone, and citronellol concentration were not chan

17 structurally related alkenes (alpha-ionone, beta-ionone, and dehydro-beta-ionone), a class of compou

18 e, benzyl isothiocyanate, 1-hexen-3-one, (E)-beta-ionone, and methyl benzoate were the most odour-act

19 r the quantification of beta-damascenone and beta-ionone, and the crucial influence of ethanol conten

20 itive rod rhodopsin is also expected to bind beta-ionone at sufficiently high concentrations because

21 A Principal Component Analysis showed that beta ionone, benzaldehyde, 6-methyl-5-hepten-2-one, toge

22 ne allosteric binding site for retinoid, but beta-ionone binds to the latter type of rhodopsin with l

23 k triangle down-apo-beta-carotenal (C27) and beta-ionone (C13).

24 (8:2, v/v) and of an apolar mixture made of beta-ionone, (+/-)-citronellal, (+)-limonene, and flavon

25 he results indicate that PhCCD1 activity and beta-ionone emission are likely regulated at the level o

26 beta-Ionone emission by flowers occurred principally dur

27 ool and alpha-terpineol) and norisoprenoids (beta-ionone), especially when the CIS temperature was se

28 /Z)-2,6-nonadienal, geraniol, phenylethanol, beta-ionone, hotrienol and dihydroactinidiolide to be od

29 Z/E)-linalool oxides, (E)-2-hexenal, phytol, beta-ionone, hotrienol, methylpyrazine and methyl salicy

30 Synthesis of beta-ionone in recombinant Saccharomyces cerevisiae is l

31 CD1A, an enzyme responsible for formation of beta-ionone in tomato.

32 (adenylate cyclase agonist), and conversely, beta-ionone-induced cell death could be blocked by cotre

33 s toxin (a G protein inhibitor) also blocked beta-ionone-induced cell death.

34 One such volatile, beta-ionone, is important to fragrance in many flowers,

35 mation of isorhodopsin or by incubation with beta-ionone (opsin agonist) killed 19-30% of rod cells.

36 indicated that the truncated retinal analog, beta-ionone, partitioned into the membranes of green-sen

37 there was an enhanced uptake of four or more beta-ionones per rhodopsin.

38 d with native PhCCD1 and further analyzed by beta-ionone quantification via RP-HPLC.

39 Sensory evaluation in humans revealed that beta-ionone reduced the odor intensity and unpleasantnes

40 ervation of (13)C nuclei introduced into the beta-ionone ring (at the C16, C17, and C18 methyl groups

41 ctive site and a specific orientation of the beta-ionone ring above the plane of the heme consistent

42 ormation in the dark, and that motion of the beta-ionone ring allows Trp265(6.48) and transmembrane h

43 lessening of the steric restraints near the beta-ionone ring and SB ends of the chromophore, (ii) di

44 ,8 and 7',8' double bonds adjacent to a 3-OH-beta-ionone ring and that the conversion of zeaxanthin t

45 tandards, indicating that the opening of the beta-ionone ring and the increase of chromophore extensi

46 to determine the relative orientation of the beta-ionone ring and the polyene chain of the chromophor

47 the retinal C6-C7 single bond connecting the beta-ionone ring and the retinylidene chain is 6-s-cis i

48 rates strong steric interactions between its beta-ionone ring and transmembrane helices H5 and H6, wh

49 The beta-ionone ring can rotate relative to the polyene chai

50 etinal's polyene chain and separation of its beta-ionone ring from Trp-265.

51 es suggested that at least one unsubstituted beta-ionone ring half-site was imperative for efficient

52 In particular, we find that the beta-ionone ring has a twisted 6-s-cis conformation, whe

53 s, we can infer whether or not the pigment's beta-ionone ring has left its binding site.

54 e crtG identified recently encoding the 2,2'-beta-ionone ring hydroxylase that further hydroxylate as

55 ketolase and the crtZ gene encoding the 3,3'-beta-ionone ring hydroxylase that were responsible for a

56 yene strain, while torsional twisting of the beta-ionone ring is maintained.

57 Most surprisingly, the beta-ionone ring is mobile within its binding pocket; in

58 addition to the crtW gene encoding the 4,4'-beta-ionone ring ketolase and the crtZ gene encoding the

59 nes that represent the polyene chain and the beta-ionone ring of retinal.

60 ely arise from weakened interaction with the beta-ionone ring of the chromophore following cis-to-tra

61 In particular, the beta-ionone ring of the retinylidene inverse agonist is

62 The current view that the beta-ionone ring of the rhodopsin chromophore vacates it

63 groups of either carbon C(1) or C(5) of the beta-ionone ring or carbon C(9) of the polyene chain.

64 three hydroxyl-bearing amino acids near the beta-ionone ring part of the retinal in opsin, A164S, F2

65 isomerization, the (2)H NMR data suggest the beta-ionone ring remains in its hydrophobic binding pock

66 ral defining the relative orientation of the beta-ionone ring to the polyene chain has both modest ba

67 rd helices H3 and H5 by the C5-methyl of the beta-ionone ring.

68 sional twisting of the polyene chain and the beta-ionone ring.

69 ues, an ordered cholesterol molecule and the beta-ionone ring.

70 carotenoids with at least one unsubstituted beta-ionone ring.

71 18 forms a cap on the pocket occupied by the beta-ionone ring.

72 a-hydroxylases attach hydroxyl groups to the beta-ionone rings (beta-rings) of carotenoid substrates,

73 also bind, as do truncated retinoids in the beta-ionone series.

74 f primary melanocytes with the OR51E2 ligand beta-ionone significantly inhibited melanocyte prolifera

75 Our results further showed that beta-ionone stimulates melanogenesis and dendritogenesis

76 off-flavor compounds (2-methyisoborneol and beta-ionone), suggesting a cyanobacterial origin.

77 genic plants led to a 58% to 76% decrease in beta-ionone synthesis in the corollas of selected petuni

78 of CCDs significantly increases the yield of beta-ionone synthesized by metabolically engineered yeas

79 -ray crystallography revealed binding of one beta-ionone to bovine green-sensitive rod rhodopsin.

80 Beta-ionone was easily identified by the high-throughput

81 ssion was not observed when methanethiol and beta-ionone were introduced simultaneously to different

82 ng, whereas the changes for alpha-ionone and beta-ionone were not obvious.

83 4-Ethyguaiacol and trans-beta-ionone were positive towards aroma, flavor and over

84 d floral nuances (with the only exception of beta-ionone) were in higher proportions.

85 release of certain odorants (e.g. linalool, beta-ionone), while flavonoids showed the opposite effec

86 rod sprouting was significantly increased by beta-ionone with concomitant increases in cAMP, pCREB, a

87 Two single-point mutants increased beta-ionone yields almost 3-fold when compared to native

88 expressing peptide-PhCCD1 constructs showed beta-ionone yields up to 4-fold higher than the strain c