ライフサイエンスコーパス: beta1 adrenergic receptor

1 stitution at residue 389 (Arg389Gly), in the beta1 adrenergic receptor.

2 a covalently conjugated TIL region from the beta1-adrenergic receptor.

3 the activation of a Gs-coupled receptor, the beta1-adrenergic receptor.

4 was strongly enhanced only by the activated beta1-adrenergic receptor.

5 ent was crucial only upon Iso stimulation of beta1-adrenergic receptor.

6 nesis in iBAT was eliminated in mice lacking beta1-adrenergic receptors.

7 rease in calcium current was attributable to beta1-adrenergic receptors.

8 the released norepinephrine on myocytes are beta1-adrenergic receptors.

9 prolonged 5 Hz stimulation when paired with beta1-adrenergic receptor activation.

10 Because morpholino silencing of the beta1 adrenergic receptor (adrb1) prevents the embryonic

11 Each was genotyped for beta1-adrenergic receptor (ADRB1) Arg389>Gly and G-prote

12 ssociated with changes in gene expression of beta1-adrenergic receptor (ADRB1) or other calcium handl

13 The beta1-adrenergic-receptor (ADRB1) antagonist metoprolol

14 ion protected myocytes from death induced by beta1-adrenergic receptor agonists by preventing cytosol

15 This GIPC effect was specific for the beta1-adrenergic receptor and was dependent on an intact

16 d extend consequences of genetically variant beta1-adrenergic receptors and G-protein receptor kinase

17 er effects for the Arg389Gly polymorphism of beta1-adrenergic receptors and the intron 16 in/del poly

18 beta1-AR (beta1-adrenergic receptor) and beta2-ARs (beta2-adrenerg

19 For prodeath GsPCRs, we explored beta1AR (beta1-adrenergic receptor) and H2R (histamine-H2-recepto

20 hyperpolarization-activated cation channels, beta1-adrenergic receptors, and NMDA receptors.

21 h post-handgrip-exercise ischaemia (PEI) and beta1 -adrenergic receptor (AR) blockade.

22 The human beta1-adrenergic receptor (AR) and hamster beta2-AR tran

23 a reciprocal down-regulation occurs between beta1-adrenergic receptors (ARs) and the cardioprotectiv

24 ably transfected with alpha1A-, alpha2A-, or beta1-adrenergic receptors (ARs) in an inducible express

25 orepinephrine acting through alpha1beta- and beta1-adrenergic receptors (ARs).

26 ter kidney cells stably expressing the human beta1-adrenergic receptor (beta 1AR) to agonist over a 2

27 The beta1-adrenergic receptor (beta(1)AR) is an essential G

28 the second extracellular loop of the cardiac beta1-adrenergic receptor (beta1-AR) are thought to cont

29 n 324 in helix 6 of the wild-type (WT) human beta1-adrenergic receptor (beta1-AR) generated mutant re

30 The beta1-adrenergic receptor (beta1-AR) is a target for tre

31 The beta1-adrenergic receptor (beta1-AR) mediates several fu

32 s study, we evaluated the impact of 2 common beta1-adrenergic receptor (beta1-AR) polymorphisms (G389

33 fect of protein kinase C (PKC) activation on beta1-adrenergic receptor (beta1-AR) regulation of the c

34 oprolol, a cardio-selective beta blocker for beta1-adrenergic receptor (beta1-AR) to examine its role

35 cids within amphipathic helix 8 of the human beta1-adrenergic receptor (beta1-AR) were mutagenized to

36 ral G-protein coupled receptors, such as the beta1-adrenergic receptor (beta1-AR), contain polyprolin

37 up of transmembrane receptors, including the beta1-adrenergic receptor (beta1-AR), is internalized th

38 (AKAP5) in trafficking and signaling of the beta1-adrenergic receptor (beta1-AR).

39 to the exclusion of caveolin-1, caveolin-2, beta1-adrenergic receptors (beta1-AR), beta2-AR, Galpha(

40 The beta1 adrenergic receptor (beta1AR) is recognized as a c

41 ST reduces activation of the MAPK pathway by beta1-adrenergic receptor (beta1AR) agonists.

42 Based on bioinformatic analysis, beta1-adrenergic receptor (beta1AR) and other components

43 y zinterol or isoproterenol plus a selective beta1-adrenergic receptor (beta1AR) antagonist CGP 20712

44 Antibodies to the beta1-adrenergic receptor (beta1AR) are detected in a su

45 hingosine-1-phosphate receptor 1 (S1PR1) and beta1-adrenergic receptor (beta1AR) are G-protein-couple

46 We found that administration of the beta1-adrenergic receptor (beta1AR) blocker atenolol dur

47 The beta1-adrenergic receptor (beta1AR) is a G protein-coupl

48 The beta1-adrenergic receptor (beta1AR) is a key cell surfac

49 The beta1-adrenergic receptor (beta1AR) is known to be local

50 n kinase C (PKC) regulates the expression of beta1-adrenergic receptor (beta1AR) mRNA in rat C6 gliom

51 G protein-coupled receptors such as the beta1-adrenergic receptor (beta1AR) must be trafficked t

52 A tenet of beta1-adrenergic receptor (beta1AR) signaling is that st

53 beta1-Adrenergic receptor (beta1AR) stimulation confers

54 cal fragment screening of a thermostabilized beta1-adrenergic receptor (beta1AR) using surface plasmo

55 has decreased function, and a variant of the beta1-adrenergic receptor (beta1Arg389) has increased fu

56 Here, we hypothesized that activation of beta1-adrenergic receptors (beta1ARs) localized to ghrel

57 beta1-adrenergic receptors (beta1ARs) mediate catecholam

58 ure, in part, through chronic stimulation of beta1 adrenergic receptors (betaARs) on cardiac myocytes

59 yl terminus as bait, we identified the novel beta1-adrenergic receptor-binding partner GIPC in a yeas

60 In contrast, during beta1 -adrenergic receptor blockade, LV apical rotation,

61 gth during post-exercise ischaemia (PEI) and beta1 -adrenergic receptor blockade.

62 Adrenergic influences were reduced by the beta1-adrenergic receptor blocking agent metoprolol (1.5

63 PIST controls trafficking of the interacting beta1-adrenergic receptor both in the anterograde, biosy

64 Using the beta1-adrenergic receptor carboxyl terminus as bait, we

65 r this interaction is the Ser residue of the beta1-adrenergic receptor carboxyl-terminal ESKV motif.

66 the application of MembStruk and HierDock to beta1-adrenergic receptor, endothelial differential gene

67 Beta1-adrenergic receptors, expressed at high levels in

68 A (PKA), and this is pivotal to activate the beta1-adrenergic receptor gene (Adrb1) and downstream ta

69 reversal of gene expression controlled by a beta1-adrenergic receptor gene network.

70 rotein, GIPC, co-immunoprecipitates with the beta1-adrenergic receptor in COS-7 cells.

71 ailing hearts, because of desensitization of beta1-adrenergic receptor in heart failure.

72 involvement of the TGN in down-modulation of beta1-adrenergic receptor in response to persistent isop

73 n the basal forebrain as well as alpha2- and beta1-adrenergic receptor in the anterior cingulate cort

74 Surprisingly, knockout of beta1-adrenergic receptors in ASCs did not prevent cold-

75 lated because of, for example, activation of beta1-adrenergic receptors in myocardium.

76 Because signaling through the beta1 adrenergic receptor is a key determinant of cardia

77 ity of two prototypical GPCRs, opsin and the beta1-adrenergic receptor, is impaired upon cholesterol

78 We find that the predicted structure of beta1-adrenergic receptor leads to a binding site for ep

79 r findings reveal mechanistic differences in beta1-adrenergic receptor-mediated catalytic activation

80 beta1-adrenergic receptor-mediated ERK1/2 activation was

81 nd, the frontal cortex alpha1-, alpha2-, and beta1-adrenergic receptor mRNA levels were reduced throu

82 Neither the Arg389Gly polymorphism in the beta1 adrenergic receptor nor polymorphisms in the beta2

83 se tissue (iBAT) that involves activation of beta1-adrenergic receptors, proliferation of PDGFRA+ adi

84 rsely, astrocyte-conditional knockout of the beta1-adrenergic receptor reduced the size of gray matte

85 of autoimmune antibodies against the cardiac beta1-adrenergic receptor related to dilated cardiomyopa

86 pression of GIPC had no observable effect on beta1-adrenergic receptor sequestration or receptor-medi

87 ys, this study advances our understanding of beta1-adrenergic receptor signaling and regulation while

88 the t-tubular region and is responsible for beta1-adrenergic receptor signaling-mediated enhancement

89 oid hormone-responsive, and are regulated by beta1-adrenergic receptor signaling.

90 ndrial function and is mediated, in part, by beta1-adrenergic receptor signaling.

91 These data suggest that GIPC can regulate beta1-adrenergic receptor-stimulated, Gi-mediated, ERK a

92 Our data also demonstrate that beta1-adrenergic receptor stimulation activates the mito

93 FLJ00018 is phosphorylated and activated by beta1-adrenergic receptor stimulation-induced EGF recept

94 ave demonstrated that signaling via specific beta1-adrenergic receptor subtypes (beta1ARs) promotes b

95 xplore the structural dynamics of the turkey beta1-adrenergic receptor (tbeta1AR) bound with nine dif

96 When applied to the beta1-adrenergic receptor, the method generated 13 novel

97 NE promotes retrieval via the stimulation of beta1-adrenergic receptors, the production of cAMP, and

98 pinephrine (10 micromol/L), mediated through beta1-adrenergic receptors, tissues were freeze clamped.

99 , whereas gene expression of ADRB1 (encoding beta1-adrenergic receptors) was decreased at ZT14 versus

100 Using (13)C methyl methionine NMR for the beta1-adrenergic receptor, we identify ligand efficacy-d

101 tified squamous cells, but M1-muscarinic and beta1-adrenergic receptors were not detected.

102 carboxyl-terminal cytoplasmic domain of the beta1-adrenergic receptor, which does not bind either to

103 These cells also express the beta1-adrenergic receptor with no beta2-adrenergic recep

104 Stimulation of the beta1-adrenergic receptor with xamoterol, a specific par