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1 adrenoceptor (1000-fold selectivity over the beta1-adrenoceptor).
2 y analogous to, if not as pronounced as, the beta1-adrenoceptor.
3 eta3-adrenoceptor seems similar to the human beta1-adrenoceptor.
4 d to its antagonistic effects on presynaptic beta1-adrenoceptors.
5 ransmission via an inhibition of presynaptic beta1-adrenoceptors.
6 different agonist conformations of the human beta1-adrenoceptor: 1) where classic agonists (catechola
7  saline or prenalterol (0.1 or 1.0 mg/kg), a beta1 adrenoceptor agonist that increases cardiac rate,
8 l significantly increased peak IBa while the beta1-adrenoceptor agonist dobutamine and beta3-adrenoce
9            Bath application of the selective beta1-adrenoceptor agonist xamoterol hemifumarate (10 mi
10 constriction or on activation of alpha1- and beta1-adrenoceptors and miR-212/132 led to repression of
11  a manner similar to those observed at human beta1-adrenoceptors and unlike those seen at beta2-adren
12 ta2- and beta1-adrenoceptors, chimeric beta2/beta1-adrenoceptors, and receptors with single-point mut
13 heir therapeutic effects in migraine through beta1 adrenoceptor antagonist actions in the thalamus.
14                                          The beta1-adrenoceptor antagonist 1-[2-((3-Carbamoyl-4-hydro
15                     Pretest infusions of the beta1-adrenoceptor antagonist atenolol into either the h
16             In the presence of the selective beta1-adrenoceptor antagonist betaxolol hydrochloride (3
17         An L-type calcium channel blocker or beta1-adrenoceptor antagonist protected working memory f
18                       Metoprolol, a specific beta1-adrenoceptor antagonist, also reversibly enhanced
19 re-evaluated LK 204-545 (1), (1) a selective beta1-adrenoceptor antagonist, and discovered it possess
20 ntagonist, but not by CGP 20712A, a specific beta1-adrenoceptor antagonist.
21                              Novel selective beta1-adrenoceptor antagonists for concomitant cardiovas
22  (e.g., cimaterol) are potently inhibited by beta1-adrenoceptor antagonists, and 2) a low-affinity se
23 e] are relatively resistant to inhibition by beta1-adrenoceptor antagonists.
24 ockers have poor selectivity for the cardiac beta1-adrenoceptor (AR) over the lung beta2-AR.
25 identified transmembrane region (TM)4 of the beta1-adrenoceptor as key for this low-affinity conforma
26 ice had equivalent anti-LM defenses, whereas beta1-adrenoceptor (beta1AR)(-/-) FVB/NJ mice had lower
27 ed by a cocktail of an alpha1-(prazosin) and beta1-adrenoceptor (betaxolol) blocker but not by a sele
28 ol, 6 mg x kg(-1)) or central nervous system beta1-adrenoceptor blockade (intracerebroventricular met
29                       Central nervous system beta1-adrenoceptor blockade (metoprolol) did not reduce
30                                   Peripheral beta1-adrenoceptor blockade commenced 6 hrs after lethal
31                                   Peripheral beta1-adrenoceptor blockade offers anti-inflammatory and
32                                   Peripheral beta1-adrenoceptor blockade through daily intraperitonea
33 ic responses that are primarily dependent on beta1-adrenoceptors but responses to sustained stress ar
34                                       At the beta1-adrenoceptor, CGP 12177 potently antagonizes agoni
35                         Wild-type beta2- and beta1-adrenoceptors, chimeric beta2/beta1-adrenoceptors,
36 e low-affinity pharmacology of the secondary beta1-adrenoceptor conformation.
37 ajor role in the generation of the secondary beta1-adrenoceptor conformation.
38  cooperative interactions between 2 distinct beta1-adrenoceptor conformations.
39  propranolol, respectively) and abolished in beta1-adrenoceptors containing TM4 mutations vital for t
40 ned between in vivo and in vitro measures of beta1-adrenoceptor efficacy (R(2)=0.93; P<0.0001).
41                                              beta1-adrenoceptors exist in at least two active conform
42                                          The beta1-adrenoceptor exists in 2 agonist-stabilized, pharm
43                                          The beta1-adrenoceptor exists in at least 2 agonist-stabiliz
44                                          The beta1-adrenoceptor exists in two agonist conformations/s
45 +/-)CGP 12177 (BODIPY-TMR-CGP)] at the human beta1-adrenoceptor expressed in Chinese hamster ovary ce
46 -on e hydrochloride (CGP 12177) at the human beta1-adrenoceptor have provided evidence for two bindin
47 uggests that negative cooperativity across a beta1-adrenoceptor homodimer may be responsible for gene
48  dissociation rate were markedly enhanced in beta1-adrenoceptor homodimers constrained by bimolecular
49 ptors, with beta2-adrenoceptors outnumbering beta1-adrenoceptors in a ratio of 2.9 to 1.
50 r-aided ligand design, and targeting I118 in beta1-adrenoceptors is likely to increase beta1-selectiv
51 rat mesenteric small arteries causes a large beta1-adrenoceptor-mediated vasodilatation, which contra
52                                         In a beta1-adrenoceptor mutant (beta1-V189T-L195Q-W199Y) wher
53      Others suggested that TM4 has a role in beta1-adrenoceptor oligomerization.
54 e regulates the activity of agonist-occupied beta1-adrenoceptors on a very fast time scale.
55         Likewise, systemic injections of the beta1-adrenoceptor partial agonist xamoterol (3.0 or 10.
56  where either blockade or increased drive by beta1-adrenoceptors, reduced neuronal firing by a mean (
57 o determine the key residues involved in the beta1-adrenoceptor secondary conformation.
58 c nitrile afforded 19, a ligand with similar beta1-adrenoceptor selectivity and partial agonism (log
59 -dependent responses were mainly mediated by beta1-adrenoceptor signaling in TTS.
60 ription to confirm the presence of these two beta1-adrenoceptor sites/conformations and to provide st
61                                    Prolonged beta1-adrenoceptor stimulation suppresses IKs by downreg
62             Structural modeling of the human beta1-adrenoceptor suggested interaction of the side cha
63 es is a hyperfunctional variant of the human beta1-adrenoceptor that carries an arginine at position
64 ion of a single residue (W199D) in the human beta1-adrenoceptor thus abolished this secondary conform
65 ts were observed with cardiomyocyte-specific beta1-adrenoceptor transgenic mice and human heart biops
66 ed this secondary conformation and created a beta1-adrenoceptor with only one high-affinity agonist c
67 by 275-fold, to within 4-fold of that of the beta1-adrenoceptor, without affecting the affinity or se