ライフサイエンスコーパス: beta2 receptor

1 II, TxIA, and [A10L]TxIA at the alpha4(R185I)beta2 receptor.

2 ing characteristics similar to the wild-type beta2 receptor.

3 was confined to the amino terminus of the 0K-beta2 receptor.

4 ich is required for its interaction with the beta2 receptor.

5 ng site crevice of the constitutively active beta2 receptor.

6 iding interaction and downregulating the TGF-beta2 receptor.

7 only observed to microspots of the beta1 and beta2 receptors.

8 fter antigen challenge through its action on beta2 receptors.

9 th enhanced downregulation and uncoupling of beta2-receptors.

10 49.1 +/- 24.6%, n = 10, P = 0.0001), and TGF-beta2 receptor (-83.6 +/- 14.4%, n = 6, P = 0.003).

11 ine labeling at the amino terminus of the 0K-beta2 receptor, a lysine-depleted beta2 receptor that re

12 hesis of chiral intermediates for beta3- and beta2-receptor agonists, antihypertensive drugs, antivir

13 onstrate that physiological coupling between beta2 receptors and maxi-K channels occurs by the cAMP-P

14 ion and migration in isolated microglia, and beta2 receptor antagonists prolonged ATP effects in brai

15 eta2-blocker) or butoxamine (10(-6) mol/L, a beta2-receptor blocker) completely eliminated the NE-ind

16 ted that resting microglia primarily express beta2 receptors but switch expression to alpha2A recepto

17 We find that when coexpressed, beta2 receptors can form heteromeric complexes with both

18 In contrast, activation of beta2 receptors caused no detectable effect on V2 recept

19 ies showed that the activation of V2 but not beta2 receptors caused pronounced recruitment of beta-ar

20 out the possibility that cell type-specific beta2 receptor clustering is associated with the raft.

21 e therefore consistent with a model in which beta2 receptor clustering is influenced by the actin cyt

22 Genetic background of the beta2-receptor contributes to susceptibility for experie

23 A modified human beta2 receptor, designated 0K-beta2, was developed for s

24 ptor-encoding mRNA, and alpha1, alpha2A, and beta2 receptor-encoding mRNA than would be predicted by

25 inding of agonist or antagonist to wild-type beta2 receptor expressed in HEK 293 cells.

26 The 0K-beta2 receptor expressed in Sf9 insect cells exhibited l

27 e (p38), Smad3, p42, JNK, RhoA, PI3K, or TGF-beta2 receptor for 2 hours, and then TGF-beta2 was added

28 (PC20), and in vitro variables of leukocyte beta2-receptor function.

29 This study investigates the impact of the beta2-receptor gene (ADRB2) polymorphism Gly16Arg on the

30 between PPH and IDC RVs was upregulation of beta2-receptor gene expression in PPH but not IDC.

31 patients with heart failure, irrespective of beta2-receptor haplotype status.

32 thrombospondin-1 knockout (TSP-1KO), and TGF-beta2 receptor II double-negative (TGF-beta2 RII DN) mic

33 eting alveolar macrophages or losing the TGF-beta2 receptor in cancer cells triggers metastatic awake

34 and antagonists confirmed the involvement of beta2 receptors in mediating microglial process dynamics

35 erythroidine is >7000 times higher at alpha4/beta2 receptors in rat forebrain than at the alpha3/beta

36 Conversely, beta2 receptors in these cells undergo etorphine-mediate

37 a2 strongly favors assembly of alpha4+alpha5+beta2 receptors, increases constitutive ligand binding d

38 ished the V2 receptor-mediated inhibition of beta2 receptor internalization.

39 inated the V2 receptor-dependent blockade of beta2 receptor internalization.

40 e current study examined the extent to which beta2 receptors located within these medial basal forebr

41 The beta2-receptor mediates the metabolic response to epinep

42 ced by beta-adrenergic agonists and binds to beta2-receptor mRNAs that display agonist-induced destab

43 In contrast, in a constitutively active beta2 receptor, MTSEA significantly inhibited antagonist

44 T cell lymphoma due to a greater display of beta2 receptors on responding CD8+ anti-tumor cytotoxic

45 terioles and small arteries dilate to NE via beta2-receptors on smooth muscle.

46 th the higher affinity of ICI 118551 for the beta2 receptor relative to that for the beta1 receptor.

47 sites in rat forebrain (predominantly alpha4/beta2 receptors) revealed marked differences in their Ki

48 uiescent cells, suggesting that constitutive beta2-receptor signaling suppresses channel activity.

49 or 1 (TACR1), and gamma-aminobutyric acid(A) beta2 receptor subunit (GABRB2) yielded evidence of asso

50 rimarily of alpha3 and alpha4, together with beta2 receptor subunits) was significantly reduced by 40

51 For example, as would be predicted from the beta2 receptor tail mutagenesis studies, NHERF binds to

52 Mutagenesis studies of the beta2 receptor tail revealed that the optimal C-terminal

53 of the 0K-beta2 receptor, a lysine-depleted beta2 receptor that retains functional characteristics o

54 The remaining primary amines in the 0K-beta2 receptor, the amino terminal amine and the epsilon

55 and Leu 217 are critical residues of the RAR beta2 receptor through which beta-arrestin 2 effects are

56 Furthermore, the degree of constitutive beta2-receptor "tone" may control the threshold for huma

57 that delta receptors, when coexpressed with beta2 receptors, undergo isoproterenol-mediated endocyto

58 cations: (1) all 16 lysines in the wild-type beta2 receptor were mutated to arginines, (2) a FLAG epi

59 13) or Gly16/Glu27 haplotype (n = 8) of the beta2-receptor were randomized to equipotent dosages of

60 However, beta2 receptors, when coexpressed with kappa receptors,