1 al hypoglycaemic events have lower levels of
betatrophin.
2 Betatrophin,
a 198-amino acid protein secreted by liver
3 The recent discovery of
betatrophin,
a protein secreted by the liver and white a
4 ta show strong positive associations between
betatrophin and FBG and insulin resistance in non-diabet
5 Betatrophin/
ANGPTL8 is a newly identified hormone produc
6 These results put into question whether
betatrophin can be developed as a therapeutic approach f
7 Expression of
betatrophin correlates with beta cell proliferation in o
8 receptor antagonist S961, shown to increase
betatrophin gene expression and stimulate beta-cell repl
9 owed that subjects in the highest tertile of
betatrophin had higher odds of having T2D (odd ratio [OR
10 Betatrophin has not yet been shown to have an effect on
11 Betatrophin has previously been named RIFL, lipasin, and
12 None of these factors, including
betatrophin,
have displayed the same activity in clinica
13 Transient expression of
betatrophin in mouse liver significantly and specificall
14 So far, no data exist about the role of
betatrophin in pregnant women with a history of Roux-En-
15 TC and LDL showed negative association with
betatrophin in T2D subjects.
16 Betatrophin is a liver and adipose tissue-derived protei
17 Betatrophin is a newly described hormone, which potently
18 Therefore, lipasin/
betatrophin is nutritionally-regulated hepatokine that i
19 ny endocrine and paracrine factors, of which
betatrophin is the newest described, increase beta cell
20 n (also known as C19ORF80, RIFL, ANGPTL8 and
betatrophin)
is a newly discovered circulating factor th
21 lternatively called TD26, RIFL, Lipasin, and
Betatrophin)
is a newly recognized ANGPTL family member
22 Little is known about
betatrophin level in humans and its association with T2D
23 During the OGTT, basal and dynamic
betatrophin levels at 60' were positively associated wit
24 Our data show a significant difference in
betatrophin levels between non-diabetic (731.3 (59.5-106
25 there was a decrease in basal and stimulated
betatrophin levels during the OGTT in all three patient
26 dial hypoglycaemic events, basal and dynamic
betatrophin levels during the OGTT were lower than in th
27 Serum
betatrophin levels in humans correlate with improved adi
28 To examine subfatin, preptin and
betatrophin levels in plasma and aqueous in patients wit
29 Plasma and aqueous subfatin, preptin and
betatrophin levels were analyzed by ELISA (enzyme-linked
30 Plasma and aqueous
betatrophin levels were higher in Group DR compared to g
31 also taken for plasma subfatin, preptin and
betatrophin levels.
32 Subfatin, preptin and
betatrophin molecules may have an important role in the
33 At present, however, the effects of
betatrophin on human beta-cells are not known.
34 ike protein 8 (ANGPTL8) was the long-sought "
betatrophin"
that could control pancreatic beta cell pro
35 Using this model, we identify a hormone,
betatrophin,
that is primarily expressed in liver and fa
36 Thus,
betatrophin treatment could augment or replace insulin i
37 Plasma level of
betatrophin was measured by ELISA in 1603 subjects: 1047
38 It was only in the RYGB group that
betatrophin was negatively related to the disposition in
39 Betatrophin was positively correlated with age, BMI, wai