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1  3839 injuries recorded (997 e-scooter, 2842 bicycle).
2 step rearrangements were observed (cis-[6,5]-bicycles).
3 w approach for generating fused macrocycles (bicycles).
4 in mild-graded exercise task on a stationary bicycle.
5 e quaternary-and a decorated [3.2.2]-bridged bicycle.
6  activity if 50% of short trips were made by bicycle.
7 es, which as expected produced the 7/5 fused bicycles.
8 m catalysis provides the analogous cis-fused bicycles.
9 on mark5.2.0 and inverted question mark6.2.0 bicycles.
10 .e., similar handlebar oscillations) on both bicycles.
11 scooters and 340 per 100 000 inhabitants for bicycles.
12  motorbikes and 10.0% (n = 84) (P = .82) for bicycles.
13 cyclization to [3.2.1], [3.3.1], and [4.3.1] bicycles.
14 alkyl-substituted oxetanes and fused oxetane bicycles.
15 35Hz), and this suppression was stronger for bicycling.
16 volatile organic compounds (VOCs) from urban bicycling.
17 s adjustments of motor output, like riding a bicycle?
18 skets comprise a benzene base fused to three bicycle[2.2.1]heptane rings that extend into phthalimide
19 tly implicated sports were baseball (28.6%), bicycling (23.1%), and softball (6.7%).
20 oxyl-8-formyl-bicyclo[4,3,0]non-8(9)-enes or bicycle[4,3,0]non-1(9)-en-8-ones in varying yields with
21                  This resulted in the potent Bicycle 46 with nanomolar affinity to TSLP (K(D) = 13 nM
22 l dwellers were significantly more likely to bicycle (68.3% versus 15.9%; p<0.001) to work than urban
23 From 2017 to 2022, the US recorded 2 499 843 bicycle (95% CI, 1 948 539-3 051 147), 304 783 scooter (
24  scooter (95% CI, 232 466-377 099), 45 586 e-bicycle (95% CI, 17 684-73 488), and 189 517 e-scooter (
25 s; a higher percentage of commuters who walk/bicycle, a marker for neighborhood wealth, showed decrea
26  fusion of 5-membered rings within a [3.3.0]-bicycle, a motif present in (-)-presilphiperfolan-8-ol.
27                                     However, bicycling ability remains surprisingly unaffected in mos
28 wide range of functionalized [3.3.1]-bridged bicycles along with an exocyclic olefin and an all-carbo
29                     A BTC incorporating this Bicycle also demonstrated potent antitumor activity and
30                                     Annual e-bicycle and e-scooter injuries increased from 751 (95% C
31 ining consisted of three months of low-level bicycle and treadmill exercise such that minute ventilat
32 ented structure, including two hetero-[3.3.1]bicycles and a combination of fused, bridged, and macroc
33                      Various trans-5,6-fused bicycles and C2-substituted cyclobutanones were obtained
34 f the cueing effects (e.g., those induced by bicycles and cameras) behaved liked faces and bodies: th
35 ield potential recordings directly comparing bicycling and walking in Parkinson disease patients with
36 contrast the oscillatory dynamics underlying bicycling and walking in the basal ganglia.
37   In patients without freezing of gait, both bicycling and walking led to a suppression of subthalami
38  land uses to encourage active travel (i.e., bicycling and walking) are promising strategies for desi
39 fic types of physical activity as walking or bicycling and work or occupational activity, may be asso
40 ical activity (such as jogging, running, and bicycling) and sedentary behavior (such as spending hour
41 n accident with her learned knowledge of the bicycle, and steer away or brake.
42 ower drills, desk lamps, desk fans, cameras, bicycles, and cars) are also attenuated by inversion.
43 by a car while on motorbikes, three while on bicycles, and four as pedestrians.
44 ree-dimensional systems such as spirocycles, bicycles, and fused rings were excellent substrates, ena
45  fishing, motor vehicles, ships, submarines, bicycles, and other portable power systems in the future
46 n approximately 45 min if driving, 65 min if bicycling, and 85 min if walking.
47           Increasing active travel (walking, bicycling, and public transport) is promoted as a key st
48 work by private transport, public transport, bicycling, and walking, respectively.
49 reasing popularity of sports such as skiing, bicycling, and windsurfing.
50 es (bicycles, scooters, electric bicycles [e-bicycles], and electric scooters [e-scooters]) were obta
51  These compounds which share a benzimidazole bicycle are effective when administered in vivo at unbou
52                                    Saturated bicycles are becoming ever more important in the design
53                                        Rigid bicycles are becoming more popular in the pharmaceutical
54                                              Bicycles are constrained bicyclic peptides that represen
55   Under exceptionally mild conditions, these bicycles are converted to highly functionalized medium-s
56                                              Bicycles are entropically constrained peptides stabilize
57                                        These bicycles are significant because they have defined exit
58                                 Baseball and bicycling are leading contributors.
59 y dynamic (2+3) assembly of a cagelike macro-bicycle around a trifurcated trispyridinium pi guest.
60                      These results introduce Bicycles as a potential antiviral modality to tackle new
61 m precursor and pantetheine, uniting initial bicycle assembly common to all carbapenems with later ta
62                                    Increased bicycle availability could help eliminate HIV.
63 Malawi and assessed the effect of increasing bicycle availability on expanding treatment coverage.
64                                       We use bicycle-based, mobile measurements ( approximately 85 h)
65  Much like when one learns to type or ride a bicycle, BCI users report transitioning from a deliberat
66 igidification of the styryl into an aromatic bicycle, better if including a H-bond donor NH, such as
67  this work enhances the scope of the [1.1.1]-bicycle beyond that of a mere "spacer" unit and presents
68 ries against SARS-CoV-2 Spike yielded unique Bicycle binders across the entire protein.
69 ort the formation of an intermediate [3.2.0] bicycle but also point to an alternative pathway for the
70                      We project increases in bicycling by mid-century in NYC, but this trend may reve
71 um and palladium catalysts, decalins and 7,6-bicycles can be obtained with dichotomous stereochemical
72 lection followed by chemical optimization of Bicycles can deliver potent drug conjugates with favorab
73            Enantiomerically enriched [3.1.0] bicycles containing vicinal quaternary centers were synt
74 estrian struck by motorized vehicle (10.7%), bicycle crash (6.3%), and struck by blunt object, fists,
75 k, or bus crashes (26.7%), and pedestrian or bicycle crashes (25.3%).
76  fatally or seriously injured while riding a bicycle during the day in Maryland in 1985-1997 (cases,
77 hicle injuries (bicycles, scooters, electric bicycles [e-bicycles], and electric scooters [e-scooters
78  patients underwent 2 symptom-limited supine bicycle echocardiograms separated by an interval of 1 to
79                                       Supine bicycle echocardiography and TME have been used for eval
80                                       Chiral bicycles: Enantioenriched bicyclo[5.3.0]decatrienes were
81 xercised on three occasions for 120 min on a bicycle ergometer at 50 % maximum velocity of O2 uptake
82 and 1.8) were provided daily by increases in bicycle ergometer exercise time.
83                   Exercise tolerance using a bicycle ergometer showed increased exercise endurance fr
84 re assessed with a standardized treadmill or bicycle ergometer test protocol at baseline and week 30:
85 ng the Trier Social Stress Test (stress) and bicycle ergometer training (sport).
86  combination for 3 hours during intermittent bicycle ergometer training in a randomized, crossover, d
87 overy from an exhaustive 1-2 min sprint on a bicycle ergometer with a workload of 400 W.
88 also underwent upright exercise testing on a bicycle ergometer with analysis of respiratory gas excha
89 cise stress test on an electronically braked bicycle ergometer.
90 imal graded exercise test was performed on a bicycle ergometer.
91 asured at rest and during fixed low-workload bicycle ergometry (50, 75, and 100 W, each for 3 minutes
92 ng with measures of BP response taken before bicycle ergometry testing.
93 ess (anger recall and mental arithmetic) and bicycle ergometry were evaluated in patients with implan
94              T-wave alternans, assessed with bicycle ergometry, and SAECG were measured before EPS.
95 graphy, Holter monitoring, echocardiography, bicycle ergometry, measurement of N-terminal pro-B-type
96 d during incremental atrial pacing or supine bicycle ergometry.
97 t defines this clade-the 3-hydroxypropionate bicycle-evolved late in Earth history as a result of a s
98 epression and time to limiting angina during bicycle exercise (exercise tolerance tests), performed a
99 ent and sonographer preference, makes supine bicycle exercise a valuable stress echocardiographic mod
100  determine the hemodynamic effects of supine bicycle exercise and functional capacity during upright
101 chemia was present in 92% of patients during bicycle exercise and in 58% of patients during mental st
102 nticipatory blood pressure (BP) responses to bicycle exercise and LV mass in the Kuopio Ischemic Hear
103                       Participants underwent bicycle exercise and psychological stress testing with r
104 ntrol subjects while performing both maximal bicycle exercise and single leg knee-extensor exercise.
105  catheterization and echocardiography during bicycle exercise at low and conventional work loads (i.e
106  resonance imaging at rest and during supine bicycle exercise before and after sildenafil.
107 higher ejection fraction at rest and at peak bicycle exercise compared with patients without daily li
108 oration of intermediate stages during supine bicycle exercise echocardiography (BEE) improves the acc
109 determine the comparative accuracy of supine bicycle exercise echocardiography (SBE) and posttreadmil
110  blood flow velocity at rest and with supine bicycle exercise in 18 patients with AVS and 11 control
111 ed by ST segment depression during mental or bicycle exercise stress, although ST segment depression
112 diovascular survey, including a standardized bicycle exercise test in 1972 to 1975.
113  (n = 39) underwent a symptom-limited supine bicycle exercise test with Doppler echocardiography and
114 nk participants who performed a standardized bicycle exercise test, followed until November 2022, and
115 documented coronary artery disease underwent bicycle exercise testing and thermal pain testing.
116 ulmonary exercise testing on cardiopulmonary bicycle exercise testing correlated with calf SM area.
117 ise test underwent mental stress testing and bicycle exercise testing.
118                                              Bicycle exercise tests with measurement of respiratory g
119 /wild-type genomes) responses to 14 weeks of bicycle exercise training in 10 patients with heteroplas
120 ceptor responses were measured in the leg by bicycle exercise with and without regional circulatory o
121            Accordingly, we performed maximal bicycle exercise with respiratory gas analysis and hemod
122 5 mm Hg at rest or >/=25 mm Hg during supine bicycle exercise) participated in the open-label study o
123                                  With supine bicycle exercise, 46 +/- 25 days after device placement,
124 entilatory response to progressive intensity bicycle exercise, although some of the observed activity
125 ronary pressure and flow during rest, supine bicycle exercise, and adenosine infusion.
126  sensor-tipped guidewire during rest, supine bicycle exercise, and adenosine-mediated hyperemia.
127 (2)) and 38 controls, at rest, during supine bicycle exercise, and during hyperemia.
128 ronary pressure and flow during rest, supine bicycle exercise, and pharmacological vasodilatation wit
129 ects sequentially underwent graded-intensity bicycle exercise, atropine injection and isoproterenol i
130 tural changes, sublingual nitroglycerin, and bicycle exercise, demonstrated expected changes in measu
131   Hemodynamic and neurohormonal responses to bicycle exercise, public speaking, and the Stroop test w
132 and 4.7 +/- 1.7-fold in response to AICAR or bicycle exercise, respectively.
133                                              Bicycle exercise, which activates aPKCs and stimulates g
134 ficantly increased immediately and 3 h after bicycle exercise.
135 ith DTI at rest and during submaximal supine bicycle exercise.
136 ficantly greater in the control group during bicycle exercise.
137 rs (n = 14) underwent standardized recumbent bicycle exercise.
138 recall-as well as symptom-limited semisupine bicycle exercise.
139 t radionuclide renography at rest and during bicycle exercise.
140 rnight rest (nonexercise) or (ii) submaximal bicycle exercise.
141  INTERPRETATION: These results indicate that bicycling facilitates overall suppression of beta power.
142 ics, and with a network of buses, trams, and bicycle facilities) was transformed to match the urban f
143 mber of solid tumors, identified a number of Bicycle families with low nanomolar affinity.
144                                        These bicycles formed W(CO)(5) complexes (3) or afforded 1,2-d
145 combining a challenging pinacol coupling and bicycle-forming etherification with several additional c
146  efficiently prepare complex fused- or spiro-bicycles from diisopropyl phthalate in just one or two s
147 dvanced, chemically upgraded macrocycles and bicycles from libraries with pre-existing knowledge.
148 no smoking, being physically active (walking/bicycling &gt;/=40 min/day and exercising >/=1 h/week), and
149 ferent domains of physical activity, walking/bicycling &gt;20 minutes/d was associated with 29% lower ri
150                                   Walking or bicycling (&gt;60 minutes/day vs. hardly ever; HR, 0.88; 95
151            Chemical optimization of a second Bicycle, guided by structural biology, provided a high a
152 c injuries (bus, car, truck, pedestrian, and bicycle), gunshot or stab or slash wounds, falls, work o
153                      The boy had sustained a bicycle handlebar injury to his upper abdomen 3 weeks be
154 se of small vehicles (primarily scooters and bicycles), has become a standard transportation method i
155                        The newly synthesized bicycles have been investigated for their in vitro cytot
156 a support the positive influence of a law on bicycle helmet use among children.
157 xty-four counties in Florida had enacted the bicycle helmet-use law, while the other three counties h
158                                              Bicycle helmets offer substantial protection for the upp
159                                              Bicycle helmets, regardless of type, provide substantial
160 roach for designing lightweight and portable bicycle helmets, yet their effectiveness in real-world c
161                         We performed upright bicycle hemodynamics in 10 patients (9 men) aged 56+/-12
162              Unweighted estimates of e-bike, bicycle, hoverboard, and powered scooter-related injurie
163               A child often learns to ride a bicycle in the driveway, free of unforeseen obstacles.
164 e cycloaddition partner to construct [3.2.2] bicycles in a copper-catalyzed [4+2] cycloaddition.
165                      Florida children riding bicycles in counties where the state helmet-use law was
166 re data to estimate participation in outdoor bicycling in New York City.
167 d within these targets: a) the fused "[3.2.1]bicycle" (in gelsemine) and "oxabicycle" (in gelsedine c
168 ice participants practiced riding a reversed bicycle, in which a reversing gear inverted the handleba
169  intermediates that lead to a range of fused bicycles including the cores of various furan-, benzofur
170 ng phase, failed attempts to ride the normal bicycle indicated strong interference between the two bi
171 and connectivity, pedestrian infrastructure, bicycle infrastructure, and public transit infrastructur
172           Results also reveal that dedicated bicycle infrastructure, including bike lanes and tracks,
173 sults thus strongly support the provision of bicycle infrastructure.
174 bicycle traffic affected by the provision of bicycle infrastructure?
175                                   Exploiting Bicycles' inherent chemical combinability, we converted
176 d a series of constrained bicyclic peptides, Bicycle, inhibitors of human ACE2 by panning highly dive
177 orwegian patients who sustained e-scooter or bicycle injuries and presented to an emergency departmen
178                                         Most bicycle injuries occurred during weekdays (1586 [69.7%])
179                                Odds ratio of bicycling injury according to estimated BAC.
180 s than 0.02 g/dL, the adjusted odds ratio of bicycling injury was 5.6 (95% confidence interval [CI],
181 sin, the crushed soda can, and the collapsed bicycle inner tube exemplify the nonlinear mechanical re
182 hanism, we propose a highly reactive [3.1.0] bicycle intermediate derived from Ir(V) nitrene-mediated
183                                          The bicycle is a low-cost means of transport linked to low r
184                                     Riding a bicycle is considered a durable skill that cannot be for
185                Specifically, a fused [3.2.0] bicycle is proposed to form from dialkyl squarate-derive
186 ism for the trans-selective formation of 5,5-bicycles is investigated by using DFT calculations.
187                                              Bicycling is one of the leading causes of recreational i
188 s caused the number of bicycle trips and the bicycle kilometers traveled to increase by 60% and 90%,
189 ations suggest that the extensive Copenhagen bicycle lane network has caused the number of bicycle tr
190 , compared with a counterfactual without the bicycle lane network.
191 nto an annual benefit of euro 0.4M per km of bicycle lane owing to changes in generalized travel cost
192           In the median city, each new km of bicycle lanes is associated with ~13,400 additional km y
193  future applications of low-molecular-weight Bicycle LICA therapeutics for the treatment of diseases
194  to generate the desired coordination-driven bicycle-like wheel (90 % yield).
195                                   Simulating bicycle mode share and flows can help decide where to bu
196                              An alternative "bicycle" model for circadian regulation of membrane exci
197           Four distinct epitopes with unique bicycle molecule binding motifs were identified across t
198   This is the first example of a homodimeric Bicycle molecule inhibiting receptor complex formation,
199 onomeric peptides were converted into tandem Bicycle molecules with picomolar affinities, similar to
200                                            A bicycle-mounted measurement system was used to sample ai
201 sease underwent treadmill (n = 50) or supine bicycle (n = 50) exercise echocardiography.
202 segment (n = 90); the others occurred during bicycling (n = 7), running (n = 15), and postrace recove
203  different variations of growing a synthetic bicycle network between an arbitrary set of points route
204                          However, prevailing bicycle network development follows a slow and piecewise
205 tically the topological limitations of urban bicycle network development.
206 licable starting point for sustainable urban bicycle network planning with minimal data requirements.
207    If every city increased the extent of its bicycle network to the level of Copenhagen, Denmark, our
208 of land use, the mesoscale of pedestrian and bicycle networks and infrastructure such as Complete Str
209 I, imagination of freewheeling downhill on a bicycle (no change in heart rate, HR, or ventilation, V(
210 hesis of the fused gamma-lactam beta-lactone bicycle of proteasome inhibitor omuralide.
211 rovides access to various privileged bridged bicycles of pharmaceutical relevance.
212 vere as those of individuals who experienced bicycle or motorbike RTCs, with a higher proportion of s
213           Exercise echocardiography with the bicycle or posttreadmill approach is used in subjects wh
214 raffic crash (RTC) involving an e-scooter, a bicycle, or a motorbike were included.
215  achieve a coverage of 90%, whether driving, bicycling, or walking.
216              One reactant fraction undergoes bicycle pedal motion aborted at the C13=C14 double bond,
217          The other fraction undergoes a full bicycle pedal motion of both C11=C12 and C13=C14, result
218 n of C9'-C8' and C7'-C6' single bonds in the bicycle-pedal (s-BP) manner and structural changes in th
219 ize via distinct implementations of the same bicycle-pedal mechanism originally proposed by Warshel.
220                                    Here, the bicycle phage display platform was used in combination w
221 de and methyl shifts of the initially formed bicycle predominant formation of (-)-kolavenyl diphospha
222 phase extraction device run using a standard bicycle pump.
223 nto an azepine and then fold it into a rigid bicycle pyrroline by means of singlet nitrene-mediated n
224 tified and characterized a bicyclic peptide (Bicycle(R) molecule BCY17901), with a molecular weight o
225 uthors conducted unobtrusive observations at bicycle racks at public elementary schools statewide.
226  related verbal message were displayed above bicycle racks.
227 o secure items to automobile rooftops and to bicycle racks.
228                                              Bicycling, rather than walking, in rural areas would sub
229 sters that both multimerized and biparatopic Bicycles reduce viraemia and prevent host inflammation.
230 ine-grained representation of the Copenhagen bicycle-relevant network.
231 health and economic benefits are possible if bicycling replaces short car trips.
232 al bicycle was worse than that of the novice bicycle riders at baseline.
233 s of rising temperatures on health-promoting bicycle ridership demonstrates how challenging it is to
234                            Alcohol use while bicycle riding is associated with a substantially increa
235 icity has led us to a new class of 6-5 fused bicycle rings as minor groove recognition elements.
236 d variable foot location as the pedal of the bicycle rotated about the crank.
237 (4.4%), 4094 motorbike RTCs (78.2%), and 910 bicycle RTCs (17.4%).
238 h motorbike RTCs (1557 [39.7%]; P = .10) and bicycle RTCs (411 [47.3%]; P = .69).
239 RTCs increased by 2.8-fold in 4 years, while bicycle RTCs increased by 1.2-fold and motorbike RTCs de
240 placing their tail in a posture similar to a bicycle's kickstand.
241      Data on micromobility vehicle injuries (bicycles, scooters, electric bicycles [e-bicycles], and
242    In conclusion, "unlearning" of the normal bicycle skill precedes the initial learning of the rever
243 recedes the initial learning of the reversed bicycle skill, and a signature of such unlearning is sti
244 ndicated strong interference between the two bicycle skills.
245 nstrate that habitat creation, regulation of bicycle speed, and migration between patches increase C.
246 f cattle and horse grazing, maintaining slow bicycle speeds on occupied public trails, and artificial
247 rsatile algorithms and models in an unmanned bicycle system, realizing real-time object detection, tr
248  inhibition during the mid-power stroke of a bicycling task, which also involved co-contraction of qu
249  muscle contraction in sitting, standing and bicycling tasks.
250 FM, and 32 controls completed an incremental bicycle test to exhaustion.
251 onses were obtained during mental stress and bicycle tests.
252  were performed during the mental stress and bicycle tests.
253 f non-natural amino acids resulted in a lead Bicycle that demonstrated high affinity for Nectin-4, go
254 a fast-tracked synthesis of a [3.2.1] bisoxa bicycle that makes up the framework of many biologically
255                               Interestingly, bicycles that are derived from dimethyl acetylenedicarbo
256                                              Bicycle theft is a serious problem in many countries, an
257 cations which had experienced high levels of bicycle theft, and used the rest of the university campu
258 er $5000 (-1.48%; 95% CI, -2.45% to -0.50%), bicycle thefts (-1.82%; 95% CI, -2.93% to -0.68%), and t
259                                              Bicycle thefts decreased by 62% at the experimental loca
260 ak and enters, robberies, thefts over $5000, bicycle thefts, and thefts from motor vehicles as the 7
261 cyclization to construct the [3.2.2]-bridged bicycle, these efforts have enabled the total synthesis
262  6-methylidene penems containing [6,5]-fused bicycles (thiophene, imidazole, or pyrazle-fused system)
263 lock, which can be elaborated to the desired bicycle through sequential Fe(III)-catalyzed reductive o
264             Index participants who walked or bicycled to a clinic referred 1.03 more contacts per ind
265  risk ratio [ARR] 0.72; 95% CI 0.58-0.88) or bicycling to work (ARR 0.66; 95% CI 0.55-0.77) were sign
266 se-response relationship between duration of bicycling to work and being overweight, having hypertens
267                                  Walking and bicycling to work was associated with reduced cardiovasc
268                                        Those bicycling to work were significantly less likely to have
269                                            A Bicycle toxin conjugate (BTC) was generated by derivatiz
270                                  BT5528 is a Bicycle Toxin Conjugate, a novel class of chemically syn
271                                              Bicycle toxin conjugates (BTCs) are a promising new clas
272 urrently undergoing clinical trials, such as bicycle-toxin conjugates and peptide-dendrimer conjugate
273        To what extent is the volume of urban bicycle traffic affected by the provision of bicycle inf
274 active travel, based on spatial estimates of bicycle traffic, pedestrian traffic, and particulate con
275 11.0% vs 3.7%; P = .02) and the Movement ABC bicycle-trail task (12.9% vs 3.8%; P = .02).
276 4.2; 95% CI, 0.8-7.6; P = .02), Movement ABC bicycle-trail task (AMD, 0.8; 95% CI, 0.1-1.5; P = .03),
277      Functional electrical stimulation (FES) bicycle training is a physical rehabilitation technique
278                               This linear to bicycle transformation initiates with rapid cysteine lab
279 mbine interventions to improve pedestrian or bicycle transportation systems with interventions to imp
280 ociated with ~13,400 additional km yr(-1) of bicycle travel.
281 icycle lane network has caused the number of bicycle trips and the bicycle kilometers traveled to inc
282 ploit a large dataset of GPS trajectories of bicycle trips in combination with a fine-grained represe
283 pronged approach was taken to optimize these Bicycle tumor-targeted immune cell agonists by exploring
284  diaryl-substituted cis- and trans-fused 5,5-bicycles using a photodecarbonylation.
285                                The optimized Bicycle was conjugated to the cytotoxin Monomethyl auris
286       Although learning to ride the reversed bicycle was possible, it was slow, highly variable, impl
287 ecursor, the fused gamma-lactam beta-lactone bicycle was prepared in four steps by a sequential biscy
288     However, their performance on the normal bicycle was worse than that of the novice bicycle riders
289       Passive hindlimb exercise on motorized bicycles was applied 1 h/day, 3 days/week to the MSC+Ex
290 in the saturated bridges of the fused carbon bicycles, was synthesized.
291  80-nm-diameter opening like the spokes of a bicycle wheel.
292 hese studies reveal a strong rigidity of the bicycle, which adopts either a chair-chair or a boat-cha
293 ccess toward an array of [6,5] and [6,6] aza-bicycles, which form the core skeletons of various alkal
294 ovided a high affinity, metabolically stable Bicycle with improved physicochemical properties.
295 were used to inform the design of additional Bicycles with increased affinity and inhibition of ACE2
296  generated by derivatization of one of these Bicycles with the potent cytotoxin DM1 via a cleavable l
297 nthesis of 18- to 66-membered monocycles and bicycles with various amino acid compositions in one pot
298 ho performed extensive practice could switch bicycles without failed attempts and exhibited similar p
299 ged); and (4) the positive effect of HeO2 on bicycle work rate.
300                 Making 50% of short trips by bicycle would yield savings of approximately $3.8 billio

 
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