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1 ification of the gene encoding the mammalian bile acid transporter.
2 expression of a gene encoding a procaryotic bile acid transporter.
3 y in MDCK cells that express mEH as the only bile acid transporter.
4 iated by interactions with the apical sodium bile acid transporter.
5 at functions as an ATP-dependent canalicular bile acid transporter.
6 ile salt export pump (BSEP), a major hepatic bile acid transporter.
7 or membrane-associated segments in the liver bile acid transporter.
8 e acid-binding protein, which is a candidate bile acid transporter.
9 Chinese hamster ovary cells that lack other bile acid transporters.
10 ity resulting from the inhibition of pivotal bile acid transporters.
11 cell monolayer through passive diffusion and bile acid transporters.
12 because of altered expression of hepatocyte bile acid transporters.
13 r and the latter by down-regulation of ileal bile acid transporters.
14 gene expression for the apical Na+-dependent bile acid transporter (ABAT) and the 14-kilodalton ileal
16 cholestasis with lower expression levels of bile acid transporter Abcb11/Bsep and detoxification enz
17 ort deficiencies, as apical sodium-dependent bile acid transporter and bile salt export pump deficien
18 not involved in regulating the expression of bile acid transporter and biosynthesis enzyme genes foll
19 up-regulation of the apical sodium-dependent bile acid transporter and diminished canalicular secreti
20 to up-regulation of apical sodium-dependent bile acid transporter and down-regulation of FXR, ileal
21 velopment, including apical sodium-dependent bile acid transporter and ileal bile acid transporter in
23 o bile in unconjugated form by a canalicular bile acid transporter and is absorbed by cholangiocytes,
24 A transport systems, apical sodium-dependent bile acid transporter and Na(+) -taurocholate cotranspor
25 altered expression of genes encoding hepatic bile acid transporters and cholesterol and fatty acid me
27 ciated with genotype-specific suppression of bile acid transporters and loss of bile acid-mediated do
29 tory changes in expression levels of several bile acid transporters and regulatory genes were found i
30 porting polypeptide, apical sodium-dependent bile acid transporter) and an exporter (ATP-binding cass
31 s, such as the ileal apical sodium-dependent bile acid transporter, appear to affect both insulin sen
32 m/taurocholate cotransporting polypeptide (a bile acid transporter) as a receptor to enter hepatocyte
33 e microbiome increases gut expression of the bile acid transporters Asbt and Osta, which in turn faci
35 Expression of the apical sodium-dependent bile acid transporter (ASBT) and the ileal lipid-binding
37 of regulation of the apical sodium-dependent bile acid transporter (ASBT) by inflammatory cytokines i
38 of the cholangiocyte apical Na(+)-dependent bile acid transporter (ASBT) in bile formation is unknow
39 TM) segment 7 of the apical sodium-dependent bile acid transporter (ASBT) in substrate interaction wa
40 al expression of the apical sodium-dependent bile acid transporter (ASBT) in the rat is unaffected by
41 estinal bile acid uptake by an apical sodium-bile acid transporter (ASBT) inhibitor decreases ileal F
42 minimally absorbed apical sodium-codependent bile acid transporter (ASBT) inhibitor would lower the s
47 )-mediated gene expression and apical sodium bile acid transporter (ASBT) protein concentration were
48 e well characterized apical sodium-dependent bile acid transporter (Asbt) Slc10a2; however, the carri
51 ues V127-T149 of the apical sodium-dependent bile acid transporter (ASBT), a key membrane protein inv
53 bition of the ileal, apical sodium-dependent bile acid transporter (ASBT), blocks progression of scle
54 ibit the core of the apical sodium-dependent bile acid transporter (ASBT), effectively blocking ASBT'
58 the intestine by the apical sodium-dependent bile acid transporter (ASBT, also known as SLC10A2).
61 hepatocytes, and the apical sodium-dependent bile acid transporter (ASBT; also known as SLC10A2) expr
63 la parvula suppresses expression of the main bile acid transporter, ASBT, thus preventing bile acid r
65 and, expression and functional activity of a bile acid transporter, Bat1p, and of the V-type ATPase w
66 monstrate that deficiency of the canalicular bile acid transporter bile salt export pump (BSEP) and m
67 se (3 alpha-HSD), and a putative canalicular bile acid transporter Ca2+, Mg(2+)-ecto-adenosine tripho
69 d using polyclonal antisera to the liver BLM bile acid transporter demonstrated a gradual decrease in
70 lypeptide and rat ileal apical Na+-dependent bile acid transporter, designated Ntcp and ASBT, respect
73 Recent studies of the rat liver canalicular bile acid transporter/ecto-ATPase/cell CAM 105 (CBATP),
74 dies are the first report of regulation of a bile acid transporter expression by the ubiquitin-protea
75 jury during cholestasis, adaptive changes in bile acid transporter expression in the liver provide al
77 quenced, and expressed a bile acid-inducible bile acid transporter from Eubacterium sp. strain VPI 12
78 signaling machinery apical sodium-dependent bile acid transporter, FXR, and small heterodimer partne
79 e acid malabsorption, mutations in the ileal bile acid transporter gene (Slc10a2) lead to congenital
81 elating with suppression of critical hepatic bile acid transporter gene expression, including the pri
83 erocytes through the apical sodium-dependent bile acid transporter (gene SLC10A2) and leave the enter
85 th controls, which reduced expression of the bile acid transporter genes Asbt and Mcf2l (encodes Ost)
86 r, a lack of three-dimensional structures of bile acid transporters hampers our ability to understand
91 raction of the human apical sodium-dependent bile acid transporter (hASBT, SLC10A2) remain undefined.
95 330672, a selective inhibitor of human ileal bile acid transporter (IBAT), in patients with primary b
100 cholangitis with pruritus, 14 days of ileal bile acid transporter inhibition by GSK2330672 was gener
102 ndomised controlled crossover trial of ileal bile acid transporter inhibitor, a novel class of drug t
105 um-dependent bile acid transporter and ileal bile acid transporter inhibitors, integrin inhibitors, p
106 In humans, there are two Na(+)-dependent bile acid transporters involved in enterohepatic recircu
107 the multispecific anion transporter, cMOAT, bile acid transporters, ion-motive ATPases, glutathione
109 of bile acids and Na+ by human apical sodium-bile acid transporter is electrogenic and bidirectional
111 ein expression of the ileal sodium-dependent bile acid transporter (ISBT) in the intestinal and bilia
112 transporter a/B (OSTa/B) is a bidirectional bile acid transporter localized on the basolateral membr
113 ltiple residues to describe sodium-dependent bile acid transporter-mediated bile acid and cation tran
115 Increased ileal apical sodium-dependent bile acid transporter messenger RNA (mRNA) expression wa
116 e recent cloning of a human sodium-dependent bile acid transporter (NTCP) permits analysis of its exp
118 ase, sterol-12alpha-hydroxylase, and hepatic bile acid transporters on both sinusoidal and canalicula
119 to decreased transcription of genes encoding bile acid transporters on both the basolateral and canal
120 kilobase of the rat apical sodium-dependent bile acid transporter promoter to drive aberrant express
121 ctivity of the human apical sodium-dependent bile acid transporter promoter was enhanced, whereas the
125 y markers, including apical sodium-dependent bile acid transporter, secretin receptor, cilia and cyst
126 eased expression of the basolateral membrane bile acid transporters Slc10a1, Slc21a3 and Slc21a5, lea
127 s, Tcf1-/- mice lack expression of the ileal bile acid transporter (Slc10a2), resulting in increased
129 to down-regulation of the major basolateral bile acid transporters sodium taurocholate cotransporter
130 of AtMRP2 and AtMRP1 to transport the model bile acid transporter substrate taurocholate (despite th
131 teractions among the apical sodium-dependent bile acid transporter, the farnesoid X receptor (FXR), a
132 and protein for the apical sodium-dependent bile acid transporter, the ileal bile acid binding prote
133 icted for a candidate intestinal basolateral bile acid transporter, the in vivo functions of Ostalpha
134 tes (MTS) are known to inactivate the sodium/bile acid transporters through alkylation of a cysteine
139 ive zebrafish homologue of the apical sodium bile acid transporter, was visualized using a sensor bas
140 r loop (EL) 1 of the apical sodium-dependent bile acid transporter were determined via cysteine-scann
142 ting polypeptide (Oatp1), another sinusoidal bile acid transporter, were studied at 4 weeks of age.
143 ng sulfotransferase 2A (Sult2a) and selected bile acid transporters, whereas basal expression of thes