ライフサイエンスコーパス: biliary tract

1 ensitivity in vitro (e.g., Salmonella in the biliary tract).

2 in mouse extraintestinal organs such as the biliary tract.

3 ic disease that involves the kidneys and the biliary tract.

4 transformation of cholangiocytes lining the biliary tract.

5 for patients affected by malignancies of the biliary tract.

6 in human inflammatory diseases involving the biliary tract.

7 ransporters can only extrude Mg(2+) into the biliary tract.

8 epithelial differentiation in the kidney and biliary tract.

9 d facilitate therapeutic manipulation of the biliary tract.

10 ity and specificity in the evaluation of the biliary tract.

11 ntly (P < .05) inhibited colonization of the biliary tract.

12 lems that did not involve the gallbladder or biliary tract.

13 CA) is a type of cancer that develops in the biliary tract.

14 ing from the damaged epithelial cells of the biliary tract.

15 of malignant tumors that originate from the biliary tract.

16 s whose bile specimens were sampled from the biliary tract.

17 BC) is a highly aggressive malignancy of the biliary tract.

18 lirubin, or bile salts in the gallbladder or biliary tract.

19 in blood and decreased concentrations in the biliary tract.

20 life-threatening bacterial infection of the biliary tract.

21 us cancers, including those of the liver and biliary tract.

22 cid transporter (ISBT) in the intestinal and biliary tract.

23 s which begins in the liver tissue or in the biliary tracts.

24 onella infection of the gastrointestinal and biliary tracts.

25 of cancer and with 126 controls with normal biliary tracts.

26 ergillus colonization (respiratory tract 26, biliary tract 1) before liver transplantation were ident

27 Sites most commonly predicted were biliary tract (18%), urothelium (11%), colorectal (10%),

28 lopmental and proliferative disorders of the biliary tract; (2) to foster a better and more comprehen

29 We conclude that biliary tract abnormalities are the primary risk factors

30 to our understanding of gallstones and other biliary tract abnormalities.

31 utaneous liver biopsy in OLT recipients with biliary tract abnormalities.

32 spin-echo (3D FSE) MRC for the evaluation of biliary tract abnormalities.

33 s developed only in patients with underlying biliary tract abnormalities; the frequency of infection

34 tomic defects or evidence of aneuploidy or a biliary tract abnormality.

35 Biliary tract adenocarcinomas (BTAs), although anatomica

36 The effect of HCV infection on the biliary tract after liver transplantation (LT) is not we

37 subjects who underwent right lobe retrieval, biliary tract anatomy determined at CT cholangiography w

38 CT cholangiography accurately depicts biliary tract anatomy in living donor candidates for rig

39 Imaging findings of second-order biliary tract anatomy were compared with intraoperative

40 bs, MBECs 5 to 8, reacted strongly along the biliary tract and by immunoblot analysis, reacted with s

41 ngiography enables accurate depiction of the biliary tract and detection of biliary complications in

42 ted by two radiologists for depiction of the biliary tract and ductal anastomosis and for complicatio

43 inflammatory obstruction of the extrahepatic biliary tract and intrahepatic bile ducts.

44 ver fibrosis is caused by obstruction of the biliary tract and is associated with early activation of

45 represents the most common malignancy of the biliary tract and is highly lethal with less than 5% ove

46 ent was ineffective against infection of the biliary tract and large intestine.

47 arly carcinogenic event in the human hepatic biliary tract and one that is consistent with a frequent

48 tients and revealed findings from the liver, biliary tract and pancreas in 55% of examined patients (

49 t findings or manifestations from the liver, biliary tract and pancreas were fatty liver (20%, 44/220

50 hose originating in the oesophagus, stomach, biliary tract and pancreas, but not in the colon, displa

51 patient spending for pancreatic, gallbladder/biliary tract, and gastric cancer decreased.

52 lignancies of the esophagus, stomach, colon, biliary tract, and liver.

53 o evaluate the intrahepatic and extrahepatic biliary tract, and MRI also provides information about t

54 PSC and determine the location of PSC in the biliary tract, and then compared the findings with those

55 es (characterized by the progressive loss of biliary tract architecture) continue to occur after live

56 ining to the histopathology of the liver and biliary tract are reviewed.

57 y syndrome cholangiopathy, MRCP depicted the biliary tract as clearly as did ERCP (n = 9).

58 langiocytes function as a signaling "hub" in biliary tract-associated injury.

59 Intraductal papillary neoplasm of the biliary tract (B-IPN) is a scarcely known entity in our

60 d noted the presence of variant second-order biliary tract branching anatomy.

61 l systems of mice revealed tuft cells in the biliary tract but not the normal pancreatic duct.

62 Although infection of the intestinal and biliary tracts by Cryptosporidium parvum is a major prob

63 The study included 411 cases with biliary tract cancer (237 gallbladder, 127 extrahepatic

64 e-care (BSC) benefits patients with advanced biliary tract cancer (aBTC) more than BSC alone is uncle

65 atment currently is recommended in localized biliary tract cancer (BTC) after surgical resection.

66 Biliary tract cancer (BTC) has a poor prognosis with lim

67 Lifetime risk of biliary tract cancer (BTC) in primary sclerosing cholang

68 Biliary tract cancer (BTC) is potentially influenced by

69 Biliary tract cancer (BTC) is rare and has limited treat

70 The benefit of adjuvant therapy (AT) for biliary tract cancer (BTC) is unclear, with conflicting

71 ays an important role in the pathogenesis of biliary tract cancer (BTC).

72 ave been associated with chemo-resistance in Biliary Tract Cancer (BTC).

73 ts (pts) with hepatocellular (HCC, n=33) and biliary tract cancer (BTC, n=37) were enrolled into a ph

74 ally verified locally advanced or metastatic biliary tract cancer (including cholangiocarcinoma and g

75 cers: anaplastic thyroid carcinoma (n = 36), biliary tract cancer (n = 43), gastrointestinal stromal

76 the risk for primary liver and extrahepatic biliary tract cancer among 186,395 patients hospitalized

77 ic differences in these distinct subtypes of biliary tract cancer and demonstrates that approximately

78 literature on adjuvant therapy for resected biliary tract cancer and provide recommended care option

79 herapy in second-line treatment for advanced biliary tract cancer and the reference regimen for furth

80 Treatment options for patients with advanced biliary tract cancer are limited.

81 ellular biology, diagnosis, and treatment of biliary tract cancer are reviewed.

82 in, we evaluated the role of beta-catenin in biliary tract cancer by sequencing the third exon of the

83 Exposure of the resistant biliary tract cancer cell line HuCCT1 but not the suscep

84 A quantitative high-throughput screen using biliary tract cancer cell lines had identified the small

85 39 patients enrolled in the MyPathway HER2 biliary tract cancer cohort between Oct 28, 2014, and Ma

86 Patients were eligible for the biliary tract cancer cohort if they were aged 18 years o

87 e aged 18 years or older with HER2-amplified biliary tract cancer confirmed by in-situ hybridisation

88 onfirmed or cytologically confirmed advanced biliary tract cancer from hepatobiliary oncology referra

89 Advanced biliary tract cancer has a poor prognosis.

90 d in Shanghai, China, where the incidence of biliary tract cancer has been increasing in recent decad

91 multidisciplinary management, patients with biliary tract cancer have a poor outcome.

92 sion-free survival of patients with advanced biliary tract cancer in combination with cisplatin and g

93 Biliary tract cancer is a group of highly aggressive mal

94 d-line systemic therapy options for advanced biliary tract cancer on the basis of advancements of our

95 n to chemotherapy for patients with advanced biliary tract cancer remains investigational.

96 47 patients were enrolled; 223 patients with biliary tract cancer resected with curative intent were

97 zed controlled trial, patients with resected biliary tract cancer should be offered adjuvant capecita

98 tumorigenesis and genetic landscape of each biliary tract cancer subtype, which facilitates precisio

99 Common genes implicated in biliary tract cancer tumorigenesis include IDH1, IDH2, F

100 ad previous chemotherapy or radiotherapy for biliary tract cancer were also excluded.

101 , 2018, 43 patients with BRAF(V600E)-mutated biliary tract cancer were enrolled to the study and were

102 Data on incident biliary tract cancer were retrieved from the Swedish Can

103 e overall survival in patients with resected biliary tract cancer when used as adjuvant chemotherapy

104 Cholangiocarcinoma (CCA) is a rare biliary tract cancer with a low five-year survival rate

105 nresectable, locally advanced, or metastatic biliary tract cancer with an Eastern Cooperative Oncolog

106 nresectable, locally advanced, or metastatic biliary tract cancer with disease progression on previou

107 , metastatic, locally advanced, or recurrent biliary tract cancer, an Eastern Cooperative Oncology Gr

108 ith GemCis alone as first-line treatment for biliary tract cancer, and the study was discontinued ear

109 he advancements in molecular pathogenesis of biliary tract cancer, especially in an era of personalis

110 y responses may predispose to gallstones and biliary tract cancer, suggesting the need for future stu

111 mmation in the development of gallstones and biliary tract cancer, we examined the risk associated wi

112 ctivity in patients with BRAF(V600E)-mutated biliary tract cancer, with a manageable safety profile.

113 SNPs and haplotypes with biliary stones and biliary tract cancer.

114 anisms for the initiation and progression of biliary tract cancer.

115 ive means for the diagnosis and treatment of biliary tract cancer.

116 ations should be considered in patients with biliary tract cancer.

117 sion-free survival in patients with advanced biliary tract cancer.

118 y unselected, locally advanced or metastatic biliary tract cancer.

119 viously untreated metastatic or unresectable biliary tract cancer.

120 pared with observation following surgery for biliary tract cancer.

121 is overexpressed or amplified in a subset of biliary tract cancer.

122 therapy in patients with BRAF(V600E)-mutated biliary tract cancer.

123 ne how H. pylori might influence the risk of biliary tract cancer.

124 motherapy regimen for patients with advanced biliary tract cancer; expression of VEGF and its recepto

125 unresectable, locally advanced or metastatic biliary tract cancer; had disease measurable per Respons

126 Biliary tract cancers (BTC) are a rare and aggressive co

127 Biliary tract cancers (BTC) comprise a group of uncommon

128 Biliary tract cancers (BTC), which encompass intra- and

129 Biliary tract cancers (BTCs) are uncommon, but highly le

130 ROUNDMEK inhibitors have limited activity in biliary tract cancers (BTCs) as monotherapy but are hypo

131 Biliary tract cancers (BTCs) contain several actionable

132 The management of biliary tract cancers (BTCs) has been challenging partly

133 has a female predominance, whereas the other biliary tract cancers (BTCs) have a male predominance, s

134 aining of tissue microarrays (TMAs) from 223 biliary tract cancers (BTCs) was used to analyze candida

135 Biliary tract cancers (BTCs), including intrahepatic cho

136 Biliary tract cancers (BTCs), which encompass intra- and

137 ave been associated with chemo-resistance in biliary tract cancers (BTCs).

138 2 mutations are infrequent genomic events in biliary tract cancers (BTCs).

139 2 (HER2) overexpression is seen in 4%-16% of biliary tract cancers (BTCs).

140 h include hepatocellular carcinoma (HCC) and biliary tract cancers (i.e., cholangiocarcinoma and gall

141 beta-catenin were present in 8 of 107 (7.5%) biliary tract cancers and 4 of 7 (57.1%) gallbladder ade

142 hird exon of the beta-catenin gene among 107 biliary tract cancers and 7 gallbladder adenomas from a

143 ous polyposis coli (APC) gene are present in biliary tract cancers and the APC protein modulates leve

144 Biliary tract cancers are a heterogeneous group of cance

145 Biliary tract cancers are aggressive, rare, gastrointest

146 The challenges posed by these often lethal biliary tract cancers are daunting, with conventional tr

147 f 5.47 (95% CI: 1.17-25.65) observed for the biliary tract cancers combined.

148 Biliary tract cancers constitute approximately 3% of gas

149 of targeted agents will make the subsets of biliary tract cancers even smaller but is likely necessa

150 Because most biliary tract cancers have an immune-suppressed microenv

151 ins was associated with an increased risk of biliary tract cancers in ATBC.

152 hepatic bile duct (IBD), and gallbladder and biliary tract cancers outside of the liver (GBTC) in a n

153 section is also the definitive treatment for biliary tract cancers, and liver transplantation can be

154 Biliary tract cancers, including intrahepatic, perihilar

155 Biliary tract cancers, which arise from the intrahepatic

156 a role in the pathogenesis of gallstones and biliary tract cancers.

157 responses in pancreatic and 5/12 (41.7%) in biliary tract cancers.

158 xaliplatin (GEMOX) in patients with advanced biliary-tract cancers (BTCs).

159 Bile acids have been implicated in biliary tract carcinogenesis, in part, by activating the

160 esent a unique new animal model for studying biliary tract carcinogenesis.

161 ne and has become a new standard in advanced Biliary Tract Carcinoma (aBTC).

162 Biliary tract carcinoma carries a poor prognosis, and di

163 h chemotherapeutic options remain limited in biliary tract carcinoma, radiation therapy may provide a

164 Thirty patients were studied who had PSC and biliary tract carcinoma.

165 Most biliary tract carcinomas complicating PSC can be demonst

166 Biliary-tract-carcinomas (BTC), pancreatic-ductal-adenoc

167 ancer (GBC) is the most common cancer of the biliary tract, characterized by a very poor prognosis wh

168 g cholangitis (a premalignant disease of the biliary tract) compared with controls.

169 Biliary tract complications are less well recognized.

170 study were to: (1) evaluate the incidence of biliary tract complications using a new method of side-t

171 Biliary tract complications were categorized as bile lea

172 logic, although a comparable number suffered biliary tract complications, either from obstruction or

173 or not use of the T tube leads to increased biliary tract complications.

174 nt of therapies aimed at halting the ongoing biliary tract destruction found in immune-mediated chola

175 lion), esophageal disorders ($18.1 billion), biliary tract disease ($10.3 billion), abdominal pain ($

176 privately insured patients for 4 diagnoses: biliary tract disease (odds ratio, 0.73 [95% CI, 0.55 to

177 with ADPKD had higher rates of admission for biliary tract disease (rate ratio [RR], 2.24; 95% confid

178 antially, but ADPKD remained associated with biliary tract disease (RR, 1.19; 95% CI, 1.08 to 1.31) a

179 ies have evaluated the management options of biliary tract disease after OHT.

180 d tomography may improve staging accuracy in biliary tract disease and plays a definite role in diagn

181 Absolute excess risk of biliary tract disease associated with ADPKD was larger t

182 Two patients died of reasons unrelated to biliary tract disease before the completion of treatment

183 Endoscopic management of biliary tract disease continues to be influenced by new

184 Biliary tract disease developed in 17 patients (5%) who

185 cholecystectomy has transformed the care of biliary tract disease in Mongolia.

186 Overall, biliary tract disease seems to be a distinct and importa

187 Major updates in the management of biliary tract disease using biliary endoscopy are discus

188 The ADPKD versus non-ADPKD RRs for biliary tract disease were larger for men than women (he

189 sclerosing cholangitis (PSC), a progressive biliary tract disease without approved medical therapy,

190 teremia, infective endocarditis, meningitis, biliary tract disease, and carcinoma, among others.

191 gh commonly occurring in patients with known biliary tract disease, is often cryptogenic in origin (i

192 Hospitalization rates for biliary tract disease, serious liver complications, and

193 spontaneous and fatal autoimmune polycystic biliary tract disease, with lymphocytic peribiliary infi

194 ture related to the diagnosis and therapy of biliary tract disease.

195 warrant its use in the routine diagnosis of biliary tract disease.

196 all causes and 72 deaths with gallbladder or biliary tract disease.

197 in the United States, is often the result of biliary tract disease.

198 d a hypothesis that ADPKD is associated with biliary tract disease.

199 associated with increased ICC risk included biliary tract diseases (adjusted odds ratio [AOR]: 81.8;

200 he mechanisms regulating the pathogenesis of biliary tract diseases and in devising new treatment app

201 mechanisms that underlie the pathogenesis of biliary tract diseases.

202 s (VEGFs) participate in the pathogenesis of biliary tract diseases.

203 s are more susceptible than males to several biliary tract diseases.

204 nesis play an important role in a variety of biliary tract diseases.

205 er the past year in endoscopic approaches of biliary tract diseases.

206 ndoscopy are discussed over a broad range of biliary tract diseases.

207 rum of chronic intrahepatic and extrahepatic biliary tract disorders culminating in progressive chole

208 rstanding and treatment of several liver and biliary tract disorders of childhood.

209 er, hemochromatosis, Wilson disease, several biliary tract disorders, and pathology of liver tumors,

210 (ICD-9) codes: laparoscopic cholecystectomy, biliary tract disorders, pneumonia, and cellulitis.

211 thways, as well as a possible involvement in biliary tract disorders, require further studies.

212 formation is required, such as management of biliary tract dysplasia and cancer chemoprevention in PS

213 ngiocarcinomas are malignancies arising from biliary tract epithelia that are associated with a poor

214 holangiocarcinoma (CCA), a malignancy of the biliary tract epithelium is of increasing importance due

215 erexpression of ErbB-2 in the basal layer of biliary tract epithelium led to the development of gallb

216 langiocarcinoma is a malignancy arising from biliary tract epithelium that is increasing in incidence

217 pulate the entire length of the extrahepatic biliary tract, except the gallbladder.

218 e and effective technique to reconstruct the biliary tract following hepatic transplantation.

219 carcinoma is an aggressive malignancy of the biliary tract for which effective treatment is lacking.

220 ratified by infectious source as appendix or biliary tract (group A) versus other (group B).

221 Although the effects of progesterone on the biliary tract have been implicated in the increased inci

222 (GBC), the most aggressive malignancy of the biliary tract, have a poor prognosis.

223 is a specific pattern of involvement of the biliary tract in patients with PSC and to evaluate featu

224 ls with stones and from controls with normal biliary tracts in their serum and bile biochemistries.

225 4 % (2/58), pancreatitis in 8.6 % (5/58) and biliary tract infection (BTI) in 1.7 % (1/58) of patient

226 of sialic acid in reovirus encephalitis and biliary tract infection in mice.

227 eloped early postoperative IAI (peritonitis, biliary tract infection, abdominal abscess, or enteritis

228 rse events (one acute coronary syndrome, one biliary tract infection, one other neoplasms, and two co

229 regions, CCA can be associated with chronic biliary tract inflammation owing to choledocholithiasis,

230 e oncogenic effect of the associated chronic biliary tract inflammation.

231 isfortune to have, during cholecystectomy, a biliary tract injury which required four subsequent bili

232 allow leakage of bile from the BS-overloaded biliary tract into blood, thereby protecting the liver f

233 erol in hepatocytes and secreted through the biliary tract into the small intestine, where they aid i

234 Biliary tract intraepithelial neoplasia (BilIN) is the c

235 suppressed host is frequently complicated by biliary tract involvement.

236 us strain-specific replication in the murine biliary tract is determined by both viral entry mediated

237 tient admission, with particular emphasis on biliary tract issues.

238 holangiocarcinoma (CCA), a malignancy of the biliary tract, knowledge of these receptors in biliary e

239 increased risk of chromosomal aneuploidy or biliary tract malformation.

240 ns suggest a recent increase in intrahepatic biliary tract malignancies.

241 igher LDLT admission rates were observed for biliary tract morbidity throughout the second posttransp

242 Gallbladder and biliary tract mortality and gallstone disease associatio

243 ctivity were associated with gallbladder and biliary tract mortality, and non-Hispanic Black and Mexi

244 nts had associated extraintestinal location (biliary tract [n = 3] and lung [n = 1]).

245 ciated with acute fulminant hepatic failure, biliary tract necrosis and leaks, or relapsing bacteremi

246 sults suggest that the molecular pathways of biliary tract neoplasms vary by anatomical subsite and h

247 cause of neonatal liver disease, results in biliary tract obstruction and hepatic fibrosis.

248 Nonsurgical biliary drainage in malignant biliary tract obstruction can be performed endoscopicall

249 n might be protective in liver diseases with biliary tract obstruction even without increased HGF pro

250 e enterohepatic bile acid circulation during biliary tract obstruction leads to profound perturbation

251 gen activator (uPA) might be important after biliary tract obstruction.

252 ase, whilst imaging confirmed the absence of biliary tract obstruction.

253 Gene-edited parasites colonized the biliary tract of hamsters and developed into adult fluke

254 urally and functionally heterogeneous in the biliary tract of normal rats.

255 nic fibroinflammatory syndrome involving the biliary tract, often accompanied by inflammatory bowel d

256 tract injury which required four subsequent biliary tract operations.

257 without symptoms or signs referrable to the biliary tract or pancreatic duct.

258 3 in a ciliary disease affecting the kidney, biliary tract, pancreas, and retina.

259 r the other 9 cancer sites studied (stomach, biliary tract, pancreas, cervix, endometrium, prostate,

260 ts: endometrial, cervical, ovarian, bladder, biliary tract, pancreatic, and other.

261 relationship between vascular growth and the biliary tract, particularly the molecular mechanisms tha

262 enty three Roux-en-Y patients with suspected biliary tract pathology underwent balloon-assisted enter

263 of hemolysis, recurrent viral hepatitis, and biliary tract pathology were identified; 10 other post-o

264 creased TGF-beta signaling in the kidney and biliary tract, respectively.

265 nflammation and fibrosis of the extrahepatic biliary tract, resulting in cirrhosis and end-stage live

266 hepatocellular carcinoma and cancers of the biliary tract, share high mortality and rising incidence

267 They occur throughout the biliary tract, share some histologic and clinical featur

268 tients have a high prevalence of symptomatic biliary tract stone disease.

269 ancy (in particular, cholangiocarcinoma) and biliary tract stone formation.

270 The authors report their experience with biliary tract stones in adult and pediatric heart transp

271 nd September 1994 to determine prevalence of biliary tract stones, management strategies used, and ou

272 emains a challenge for even the most skilled biliary tract surgeon.

273 ficant 38% increase in the relative risk for biliary tract surgery (P = 0.05).

274 HRS then was applied to renal failure in biliary tract surgery and to cases of coexistent renal a

275 otal of 147 women (7%) were hospitalized for biliary tract surgery in HERS.

276 gen plus progestin, one additional woman had biliary tract surgery per year.

277 The overall RH for biliary tract surgery was 1.48 (95% CI, 1.12-1.95); for

278 ents with benign bile duct strictures, prior biliary tract surgery, concurrent liver disease impactin

279 e were associated with an increased risk for biliary tract surgery, whereas statin use was associated

280 ased the rates of venous thromboembolism and biliary tract surgery.

281 rapy in postmenopausal women on the risk for biliary tract surgery.

282 ginally significant increase in the risk for biliary tract surgery.

283 fected with PSC independent of pretransplant biliary tract surgery.

284 Seventy-nine (62%) had undergone previous biliary tract surgery.

285 e infection (SSI) after gastrointestinal and biliary tract surgery.

286 iliary FGF19 has a signaling function in the biliary tract that differs from its established signalin

287 ocarcinoma is an enigmatic malignancy of the biliary tract that has recently been shown to be increas

288 Commonly found in the biliary tract, tuft cells are absent from normal murine

289 ns in the BRAF gene have been found in 5% of biliary tract tumours.

290 cholangiography enables significantly better biliary tract visualization than conventional or excreto

291 Interobserver agreement for overall biliary tract visualization was good for CT, conventiona

292 Ectopic oncogene expression in the biliary tract was accomplished by the Sleeping Beauty tr

293 Like in humans, abnormalities of the biliary tract were an invariant finding.

294 , and morphological studies of the liver and biliary tract were assessed.

295 gression of malignancy is exemplified in the biliary tract where persistent inflammation strongly pre

296 Recent papers on disorders of the liver and biliary tract which clarify their pathogenesis and atten

297 polycystic disease affecting the kidneys and biliary tract with an estimated incidence of 1 in 20,000

298 are susceptible to chronic infections of the biliary tract with Cryptosporidium parvum (CP) that may

299 r carcinoma is the most common cancer of the biliary tract with dismal survival largely due to delaye

300 leading to fibrosis and obliteration of the biliary tract with the development of biliary cirrhosis.