ライフサイエンスコーパス: binaural

1 is pitch mismatch may be related to degraded binaural abilities.

2 -the BIC reflects the difference between the binaural ABR and the sum of the monaural ABRs (i.e., bin

3 ely, and changes its spike rate according to binaural acoustic differences.

4 Binaural acoustic signals in the form of phase-locked ac

5 d multiple units in response to monaural and binaural acoustic stimulation.

6 ithin milliseconds, but the actual extent of binaural adaptation is unknown.

7 of coincidence detection affect monaural and binaural AM coding.

8 for LSO neurons to encode both monaural and binaural AM sounds.

9 For SSD-CI subjects, binaural and CT measurements were in agreement, suggesti

10 nature of overlap between systematic maps of binaural and frequency selectivity leads to representati

11 se sounds affected neither the ratio between binaural and monaural responses nor the interaural time

12 also ask how these different adaptations for binaural and spatial hearing might inform and inspire th

13 Manipulating the availability of binaural and spectral localisation cues had little impac

14 tivated cortex resulting from the overlap of binaural and tonotopic maps.

15 ere, we identify prolonged maturation of the binaural auditory brainstem in the guinea pig by trackin

16 er range of strategies for ITD coding in the binaural auditory brainstem.

17 he direction of a sound source, although the binaural auditory cues available in the acoustic sound f

18 sitive channel blockers ('photoswitches') in binaural auditory gerbil neurons to show that hyperpolar

19 endrites, however, can detect coincidence of binaural auditory inputs with submillisecond precision,

20 Low-order binaural auditory neurons with sharp frequency tuning ac

21 e medial superior olive (MSO) is part of the binaural auditory pathway, receiving excitatory projecti

22 quired submillisecond temporal precision for binaural auditory processing, reduced myelination might

23 information about sound stimuli, in part for binaural auditory processing.

24 lateral olivocochlear feedback maintains the binaural balance in neural excitability required for acc

25 A binaural beamforming algorithm was also assessed.

26 This stimulus, named amplitude modulated binaural beat, allows for a parametric and isolated chan

27 Binaural beats (BBs) have garnered attention as a highly

28 We obtained responses to binaural beats and dichotic noise bursts to characterize

29 e developed a biophysically-based model of a binaural brainstem nucleus, the medial superior olive (M

30 ere stimulated in both ears, suggesting that binaural brainstem pathways do not experience plasticity

31 bility in noise can be improved using a new, binaural broadband hearing instrument system.

32 ison, randomized crossover design study with binaural broadband hearing instruments and advanced digi

33 the QuickSIN and the HINT measures with the binaural broadband hearing instruments, when compared wi

34 d over a wide range of stimulus levels under binaural, but not monaural, conditions.

35 n affected the synaptic organization at this binaural center in the ascending auditory pathway.

36 , calibrated to reproduce known monaural and binaural characteristics of LSO, generate largely simila

37 In terms of binaural characteristics, most (ca. 53%) labeled neurons

38 ch forms a key element of auditory brainstem binaural circuitry, exhibits all of these characteristic

39 as been made in characterizing these primary binaural circuits as well as the variety of mechanisms t

40 A consistent BF and binaural class were usually observed within a patch.

41 representations of sound azimuth within two binaural clusters in the pallid bat A1: the binaural inh

42 erties, but how spatial tuning varies within binaural clusters is unknown.

43 ations are present locally within individual binaural clusters.

44 h and engineering project entitled Advancing Binaural Cochlear Implant Technology-ABCIT-as well as re

45 Both effects improve binaural coincidence detection compared with single larg

46 idelity of NM neurons, which is essential to binaural coincidence detection in nucleus laminaris.

47 ontrol the submillisecond time resolution of binaural coincidence detection, but little is known abou

48 or olive process sound-localization cues via binaural coincidence detection, in which excitatory syna

49 hase-locked signals to nucleus laminaris for binaural coincidence detection.

50 used these responses to construct inputs to binaural coincidence detector neurons in nucleus laminar

51 ion of maximal activation within an array of binaural coincidence-detector neurons that are tuned to

52 ng but not shifting the window for detecting binaural coincidence.

53 EEG) data to investigate the architecture of binaural combination for amplitude-modulated tones.

54 f the brain; this information is crucial for binaural comparisons and sound localization.

55 otentials and thus preserves the accuracy of binaural comparisons.

56 wo nuclei are the first significant sites of binaural convergence in the ascending auditory system, a

57 p is unique in that it is the first place of binaural convergence in the brainstem where monaural exc

58 onal ITD discrimination thresholds vary with binaural correlation (BC), which manipulates ITD cue rel

59 By varying the degree of binaural correlation, we could accurately change the amp

60 te that ICX neurons integrate the results of binaural cross-correlation in different frequency bands.

61 The resulting binaural cross-correlation surface strongly resembles th

62 strate that the cortical representation of a binaural cue to sound source location is profoundly cont

63 The main binaural cue used by many mammals to locate a sound sour

64 for 2 weeks to moderate noise with no stable binaural cue.

65 superior temporal gyrus (pSTG) and modulated binaural-cue response functions differently in the two h

66 Parallel pathways for binaural cues and for different frequency bands converge

67 the degree of matching between the momentary binaural cues and the preferred values of the neuron.

68 ing work focused on the unmasking enabled by binaural cues at the periphery, and little quantitative

69 haracteristic frequency (CF) and the type of binaural cues available.

70 like humans, not all mammals use both of the binaural cues for sound localization.

71 rriving at a listener's ears, distorting the binaural cues for sound localization.

72 The processing of binaural cues for sound location has been studied extens

73 We determined the ability to use binaural cues in 2 New World bats, Phyllostomus hastatus

74 coustic environment, the processing of these binaural cues needs neuronal adaptation.

75 During scanning, the spectral and binaural cues of localized sound were reproduced by a so

76 Macaques were trained to discriminate binaural cues to sound localization, eventually allowing

77 al time difference (ITD), one of two primary binaural cues used to compute the position of a sound so

78 However, neuronal sensitivity to binaural cues was reversibly altered for a few days.

79 f the sound waveforms reaching the two ears (binaural cues) as well as spectrotemporal analysis of th

80 speakers are easily segregated, even without binaural cues, but the neural mechanisms underlying this

81 e mutual relationship of sound amplitude and binaural cues, characteristic to reverberant speech.

82 tude or direction of change of the available binaural cues.

83 hleovestibular schwannomas (CVSs) that cause binaural deafness in most individuals.

84 discrepancy is that the extended periods of binaural deprivation typically experienced by cochlear i

85 sures of brainstem activity that include the Binaural Difference (BD), a measure of binaural processi

86 rizontal plane (azimuth angle) is enabled by binaural difference cues in timing and intensity.

87 Binaural directional hearing emphasizes high frequencies

88 to characterize the nature and magnitude of binaural distortions caused by modern digital behind-the

89 e two ears of the tokay gecko and found that binaural emissions could be strongly correlated: some em

90 This study assessed the contributions of binaural ENV and TFS cues for understanding speech in mu

91 that vary with separation of sound sources, binaural envelope (ENV) and temporal fine structure (TFS

92 Binaural EPSCs often showed a nonlinearity that strength

93 ummation of the monaural EPSCs predicted the binaural excitatory response but less well than the summ

94 localization by detecting the coincidence of binaural excitatory synaptic inputs distributed along th

95 Early binaural experience can recalibrate central auditory cir

96 ral ITD coding resulting from deprivation of binaural experience contributes to poor ITD discriminati

97 ng from previous deafness and deprivation of binaural experience may play a role in the poor ITD disc

98 erentially impacted by disruptions of normal binaural experience.

99 anesthetized cats that contrast maximally in binaural experience: acutely deafened cats, which had no

100 SRAF had the highest incidence of binaural facilitation for ILD cues corresponding to midl

101 longer-lasting EPSCs compensate to maintain binaural function with raised auditory thresholds after

102 ase membrane conductance during the decay of binaural glutamatergic EPSCs, thus refining coincidence

103 for assessment tools that enable testing of binaural hearing abilities.

104 late-implanted CI recipients with respect to binaural hearing and speech perception.

105 input by first finding that foundations for binaural hearing are normally established during early s

106 and cochlear implants often disrupt critical binaural hearing cues, posing challenges for individuals

107 may relate to the aetiology of amblyaudia, a binaural hearing impairment associated with bouts of oti

108 pect of restoring the functional benefits of binaural hearing in bilaterally implanted human subjects

109 implants (CIs) might promote development of binaural hearing required to localize sound sources and

110 nce: acutely deafened cats, which had normal binaural hearing until experimentation, and congenitally

111 When other cues are available (e.g., in binaural hearing), how much the auditory system actually

112 ers the potential to restore the benefits of binaural hearing, including sound source localization an

113 Binaural hearing, which involves the integration and ana

114 poral processing of low-frequency sounds for binaural hearing, which is impaired in FXS.

115 cation of a sound source requires the use of binaural hearing--information about a sound at the two e

116 rm a critical role in sound localization and binaural hearing.

117 this phenomenon has long been of interest to binaural-hearing researchers for uncovering brain mechan

118 Distinct pathways carry monaural and binaural information from the lower auditory brainstem t

119 is demonstrated that the auditory brain uses binaural information in the stimulus fine structure only

120 Binaural information was analyzed in terms of ITDs, ILDs

121 suggests that bilateral HA users' access to binaural information, namely interaural time and level d

122 previously been assessed for its effects on binaural information.

123 binaural clusters in the pallid bat A1: the binaural inhibition (EI) and peaked (P) binaural interac

124 A major inhibitory, binaural input emerges from glycinergic neurons in the i

125 y auditory brainstem structure that receives binaural inputs and is implicated in processing interaur

126 al precision in detecting the coincidence of binaural inputs dictates the resolution of azimuthal sou

127 The major excitatory, binaural inputs to the central nucleus of the inferior c

128 to these neurons' selectivity for coincident binaural inputs.

129 Binaural integration in the central nucleus of inferior

130 However, it is not known how binaural integration matures shortly after hearing onset

131 nating current stimulation (HD-TACS) affects binaural integration of dichotic acoustic features.

132 vely suggest that ILD sensitivity depends on binaural integration of excitation and inhibition within

133 the open ear's representation, and disrupted binaural integration of interaural level differences (IL

134 synchrony, effective brain connectivity, and binaural integration.

135 derlining the physiological consequences for binaural integration.

136 ssed combinations of spectral, temporal, and binaural integration.

137 y can use both binaural phase-difference and binaural intensity-difference cues to localize sound.

138 nformation mainly about ITDs and the average binaural intensity.

139 urally uncorrelated noise is consistent with binaural interaction based on cross-correlation.

140 the binaural inhibition (EI) and peaked (P) binaural interaction clusters.

141 One commonly proposed measure is the binaural interaction component (BIC), which is obtained

142 Here, we re-examined binaural interaction in low-frequency (less than approxi

143 uning and sensitivity, response latency, and binaural interaction types all showed spatial variations

144 The distributions of binaural interaction types and onset latency were also e

145 Thus, although binaural interactions are established by bilateral CIs i

146 Thus, both monaural and binaural interactions can occur at single inferior colli

147 Spike rate sensitivities to binaural interaural level difference (ILD) and average b

148 inspired by coincidence detection and by the binaural "latency hypothesis." It is known that the two

149 cy discrimination, level discrimination, and binaural lateralization.

150 ABR and the sum of the monaural ABRs (i.e., binaural - (left + right)).

151 n which ILD varies around a constant average binaural level (ABL) to approximate sounds on the horizo

152 nteraural level difference (ILD) and average binaural level cues were probed in A1 and two ventral co

153 or whichever source had the stronger average binaural level.

154 d if there are frequencies having an average binaural-level advantage over a second source.

155 The benefits of the VGHA over natural binaural listening observed in the fixed condition were

156 luence of frequency-specific features of the binaural localization cues experienced by the individual

157 or functions as diverse as Hebbian learning, binaural localization, and visual attention.

158 HAs were placed on a binaural manikin, and stimuli were presented from an arc

159 articipate in the formation of tonotopic and binaural maps in primary auditory cortex.

160 na in rabbit and in human listeners: (a) the binaural masking level difference (BMLD) and (b) differe

161 The binaural masking level difference (BMLD) is a phenomenon

162 aural processing ability was measured as the binaural masking level difference (BMLD), an established

163 Budgerigars show 8 dB of free-field binaural masking release when signal and noise are prese

164 the signal and noise are separated in space (binaural masking release).

165 8 evaluation points, alongside corresponding binaural measurements.

166 parate target speech from either monaural or binaural mixtures, as well as microphone-array recording

167 In this article, we propose a binaural model that focuses on grouping, specifically on

168 Much of the previous binaural modeling work focused on the unmasking enabled

169 of coexisting neurological deficits and the binaural nature of auditory inputs.

170 In one binaural neuron with ipsilaterally evoked IPSCs, contral

171 nsists of an array of coincidence detectors--binaural neurones that respond maximally to simultaneous

172 This suggests that binaural neurons are tuned to acoustical features of eco

173 We used in vivo patch-clamp recordings of binaural neurons in the Mongolian gerbil and pharmacolog

174 The binaural neurons of the medial superior olive (MSO) act

175 In the mammalian auditory brainstem, binaural neurons of the medial superior olive (MSO) are

176 We have explored this issue in the binaural neurons of the medial superior olive (MSO), who

177 t ascending auditory pathways, including the binaural neurons of the medial superior olive (MSO).

178 r FMRP in regulating dendritic properties of binaural neurons that are essential for low-frequency so

179 In three binaural neurons, ipsilateral sound evoked a large IPSC

180 ng the azimuth depends on the sensitivity of binaural nuclei in the auditory brainstem to small diffe

181 herited their binaural property from a lower binaural nucleus or the EI property was created in the I

182 orrection of interaural place mismatch using binaural or computed-tomography (but not pitch) informat

183 Such neurons are indeed found in the binaural pathways and are referred to as "peak-type." Ho

184 The results suggest that different binaural pathways through the low-frequency ICC may be f

185 rpen the encoding of fine structure and feed binaural pathways.

186 Understanding binaural perception requires detailed analyses of the ne

187 addition, LSO neurons are also sensitive to binaural phase differences of low-frequency tones and en

188 on, empirically-observed level-dependence of binaural phase-coding was reproduced in the framework of

189 ure tones, indicating that they can use both binaural phase-difference and binaural intensity-differe

190 Moreover, they were able to use the binaural phase-difference cue up to at least 5.6 kHz, wh

191 etermining the trough positions of simulated binaural phase-response curves.

192 Two binaural phenomena in budgerigars related to the detecti

193 Binaural processing ability was measured as the binaural

194 h predictions of cross-correlation models of binaural processing and that the psychophysical detectio

195 s impact on biological processes and suggest binaural processing as a possible contributor to more pr

196 en maintains right cortical dominance during binaural processing but does not fully overcome effects

197 non-musicians, we do not know to what extent binaural processing contributes to this advantage.

198 h ear do not fully overcome deafness-related binaural processing deficits, even after long-term exper

199 eripheral synaptopathy contributes little to binaural processing deficits.

200 aris (NL), the first nucleus responsible for binaural processing in chickens, neuronal excitability i

201 roencephalography demonstrated impairment of binaural processing in children who are deaf despite ear

202 uggest increased hearing thresholds, altered binaural processing in the brainstem and changed central

203 e majority of IC units, bicuculline degrades binaural processing involved in directional coding, ther

204 Binaural processing is crucial for discriminating sound

205 over a monaural prosthesis by harnessing the binaural processing of the auditory system.

206 h on the similarities and differences in the binaural processing strategies adopted by birds and mamm

207 More recent extensions incorporate binaural processing to account for the summation of loud

208 is (NL) is a brainstem nucleus necessary for binaural processing, analogous in structure and function

209 uation of auditory neural activity, monaural/binaural processing, and functional hearing was conducte

210 e the Binaural Difference (BD), a measure of binaural processing, we showed that a period of unilater

211 he grouping or source-separation benefits of binaural processing.

212 d interest in clinical objective measures of binaural processing.

213 rgence for nearly all ascending monaural and binaural projections.

214 locations are computed by integrating neural binaural properties and frequency-dependent pinna filter

215 of the lateral lemniscus that inherit their binaural properties directly from the lateral and medial

216 The present study is the first report on binaural properties of auditory neurons with CIs in unan

217 ation in A1 is a clustered representation of binaural properties, but how spatial tuning varies withi

218 differ in discharge patterns, latencies, and binaural properties.

219 ity of EI cells, either they inherited their binaural property from a lower binaural nucleus or the E

220 ost high-frequency-sensitive LSO neurons are binaural, receiving inputs from both ears.

221 urones in the auditory brainstem to create a binaural representation.

222 The binaural response magnitude, however, was only 64-74% th

223 rse group, even though they exhibit a common binaural response property.

224 However, nearly all possible types of binaural response to sound localization cues were repres

225 egree to which that input contributed to the binaural response.

226 One zone may contain neurons with binaural responses that combine the properties of the in

227 the various projections played in generating binaural responses, we used modeling to compute a predic

228 This projection preserves binaural segregation in that ipsilateral NM projects to

229 The precision of this binaural segregation is evident at the earliest developm

230 hat EphA4 acts as a guidance molecule during binaural segregation.

231 expressed EphA4 during the establishment of binaural segregation.

232 We find that CHL shapes A1 binaural selectivity during two early critical periods.

233 organized with respect to both frequency and binaural selectivity.

234 Recent studies have shown that binaural sensitivity adapts to stimulation history withi

235 ined a similar proportion of variance as the binaural sensitivity for the acoustic temporal fine stru

236 ulation mismatch can occur and thus diminish binaural sensitivity that relies on interaurally frequen

237 study, we investigated long-term effects on binaural sensitivity using extracellular in vivo recordi

238 In cases of mismatch, binaural sensitivity was best when the same cochlear loc

239 nhibition at the IC, we show that an initial binaural signal essentially reconfigures the circuit and

240 ural cues due to the absence of any relevant binaural signal, there is currently no proper explanatio

241 d of inhibition from the DNLL and respond to binaural signals as weakly inhibited or monaural cells.

242 ontext-dependent processing of low-frequency binaural signals in the IC.

243 ereby allows IC cells to respond to trailing binaural signals that were inhibitory when presented alo

244 itudes increased with intensity, even though binaural signals with the same ipsilateral intensities g

245 at property is a change in responsiveness to binaural signals, a change dependent on the reception of

246 To understand the relationship between binaural SOAEs, we developed a mathematical model of the

247 The primary cues for binaural sound localization are comprised of interaural

248 We measured the tuning of Ipc units to binaural sound localization cues, including interaural t

249 y nuclei with identified roles in processing binaural sound localization cues, the role of the SPON i

250 rates, and abnormal coding of frequency and binaural sound localization cues.

251 The current dominant model of binaural sound localization proposes that the lateral po

252 made still more demanding by the process of binaural sound localization that utilizes separate compu

253 is an inhibitory hub considered critical for binaural sound localization.

254 ies on the neural processing of monaural and binaural spatial cues that arise from the way sounds int

255 iCIs and approaches for promoting the use of binaural spatial cues.

256 cally to nucleus laminaris (NL), maintaining binaural specificity with projections to either dorsal o

257 the localization cue values and the neurons' binaural spectrotemporal response properties.

258 measures were air conduction audiometry and binaural speech perception in noise.

259 s the linear transformation from monaural to binaural spike responses.

260 Importantly, binaural spiking response is generated apparently from a

261 the contralateral field, confirming that the binaural SRFs were shaped by contralateral inhibition.

262 e ASSRs were assessed using varying rates of binaural stimulation (auditory click-trains; 10-50 Hz in

263 leus laminaris neurons for both monaural and binaural stimulation increased with sound intensity unti

264 de either by doubling monaural current or by binaural stimulation produced equivalent responses.

265 Relative to binaural stimulation, presentations of the VS stimuli to

266 Using this technique and monaural or binaural stimulation, responses in the IC that reflect i

267 To mimic the arrival of PSCs during binaural stimulation, two stimulus trains were summed at

268 nts and modeling showed that, for simplified binaural stimuli (EPSC pairs in a noisy background), spi

269 ally when using monaural stimuli compared to binaural stimuli.

270 These findings position our understanding of binaural summation in a broader context of work on senso

271 ed the time course and topography of ERPs to binaural syllables or complex tones in dichotic listenin

272 requires exquisitely precise integration of binaural synaptic inputs.

273 K(v)1 channels are important for preserving binaural synaptic timing.

274 rements were in agreement, suggesting little binaural-system plasticity induced by mismatch.

275 ty to insure their coincident arrival at the binaural targets.

276 The ability to process binaural temporal fine structure (TFS) information was a

277 es are important for speech intelligibility, binaural TFS cues are critical for perceptually segregat

278 l, the results from this study revealed that binaural TFS cues, especially for frequency regions belo

279 the assessment of sensitivity to changes in binaural TFS for older listeners without or with hearing

280 the TFS-AF test yielded a graded measure of binaural TFS sensitivity for all listeners.

281 The EEG responses were greater for binaural than monaural presentation of modulated tones,

282 ation depth, and were consistently lower for binaural than monaural presentation of modulated tones.

283 ial investigating the safety and efficacy of binaural therapy in five pediatric patients with DFNB9.

284 We now know of 3 bat species that cannot use binaural time cues and 2 that can.

285 this did not support significant effects of binaural timing cues in either auditory cortex.

286 ponses, adult patterns in cortical coding of binaural timing cues were measured.

287 advances, which more consistently represent binaural timing cues.SIGNIFICANCE STATEMENT Multichannel

288 Binaural tonal stimuli induced sustained depolarizations

289 racterized extracellularly with monaural and binaural tone and noise bursts (100- to 250-msec duratio

290 tal conditions: delay conditioning, in which binaural tones preceded air puffs to the right eye by 40

291 /9 carrying an eGFP-reporter gene results in binaural transduction of inner hair cells, spiral gangli

292 This experience-based adjustment of binaural tuning in the AAr helps to maintain mutual regi

293 e rates increased, which negatively impacted binaural tuning performance, measured as modulation dept

294 modification, effects of inhibition loss on binaural tuning were considerably weakened, leading to a

295 pendent, because auditory spatial acuity and binaural unmasking (a measure of the spatial contributio

296 tened to voices and nonvocal sounds or heard binaural vocalizations with attention directed toward or

297 ource locations are derived from the complex binaural waveforms of real-life sounds.

298 ignificant correlation between the degree of binaural weight asymmetry and the best azimuth.

299 s to simultaneous stimulation of both sides (binaural) were compared with responses to monaural stimu

300 The binaural whole-body response direction was compatible wi

301 efore, these neurons would be expected to be binaural with contralateral inhibition.