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1 t and the presence/absence and nature of the binder).
2 materials (i.e., graphite and thermoplastic binder).
3 isting of graphite and thermoplastic polymer binder.
4 requirement for a sufficiently potent target binder.
5 of environmental impacts relative to the PC binder.
6 and how this protein may act as a multi-drug binder.
7 d identified a benzyl amidine based fragment binder.
8 hen hybridized with various levels of CNF as binder.
9 identify PWWP2A as a novel H2A.Z-nucleosome binder.
10 le of a reduction-activated G-quadruplex DNA binder.
11 nt affinities, with Hp 2-2 being the weakest binder.
12 ein that CXXC5 is indeed an unmethylated CpG binder.
13 e effects of solar irradiation on an asphalt binder.
14 were used as electrode materials without any binder.
15 ermeable ionomers as the functional catalyst binder.
16 an be optimized to a selective submicromolar binder.
17 ere redistributed in favor of the best anion binders.
18 etic organic pigments with alkyd and acrylic binders.
19 no change could be detected for low-affinity binders.
20 s of qualitative information-binders and non-binders.
21 as well as guidance for the use of potassium-binders.
22 ce the binding behavior of already promising binders.
23 hominis, which confirmed that these are FMN binders.
24 neither as AMP nor as AICAR or succinyl-ZMP binders.
25 ring, for example, by designing bi-paratopic binders.
26 nostic applications for topology-specific GQ binders.
27 ary phosphate restriction and oral phosphate binders.
28 OFs, Zr-UiO-66, without applying pressure or binders.
29 ith less-conserved regions than known capsid binders.
30 binding, and identified 2,618 high-affinity binders.
31 y intractable fragment hits into more potent binders.
32 other methods may identify a wider range of binders.
33 ngth of high-, medium-, and low-affinity RGD-binders.
34 ss predictions among the native nucleic acid binders.
35 rials, without conductive additives or other binders.
36 PrP is a difficult target for small-molecule binders.
37 agments were progressed to discover improved binders.
38 uld result in effects distinct from ATP site binders.
39 tly attained regardless of the used painting binders.
44 rch for new drug-like selective G-quadruplex binders, a bioinspired design focused on the use of nucl
45 are useful to identify other colchicine site binders, a frequent target of structurally diverse small
47 g various interacting proteins into covalent binders, achieving specific covalent protein targeting f
49 valent (RC), and irreversible covalent (IRC) binders, affects the degradation of Bruton's Tyrosine Ki
50 ing a yeast display library, we identified a binder against terminal tyrosine of alpha-tubulin, a uni
51 for the generation of conformation-specific binders against labile membrane proteins or protein comp
55 HT-SELEX rounds and their enrichment in weak binders allows Co-SELECT to detect an evidence for the r
56 ecific molecules containing a target protein binder and an ubiquitin ligase binder connected by a lin
59 es more tightly than the previous best known binder and roughly 36 times more tightly than the design
60 that an indazole would be the stronger hinge binder and would impart increased potency when substitut
61 f accuracy, correctly assigning 87.20% of AR binders and 96.81% of GR binders in a 25% test set using
62 on the isolation of stable and high-affinity binders and catalysts, or on the design of nanomaterials
63 inguishing antibody-antigen binders from non-binders and demonstrates the challenges to address for t
64 being treated with non-iron-based phosphate binders and erythropoiesis-stimulating agents (ESA) to r
66 ch facilitates the identification of diverse binders and the fast ligandability assessment of new tar
67 der to minimize the distance between the two binders and then link the resulting compounds using flex
68 at enhancing the identification of egg-based binders and then validated on fresh and aged model picto
70 ects of lanthanum carbonate (LC; a phosphate binder) and/or nicotinamide (NAM; an inhibitor of active
71 Depending on the composition (carbon type, binder, and composition ratio), TPEs can give excellent
72 solid lubricant mixture of graphene, Aremco binder, and recycled LCO was formulated into a spray wit
73 ormer serves as an energetic initiator and a binder, and the latter is a thickening agent and the oth
75 rate hydrate (FC) is an iron-based phosphate binder approved for hyperphosphataemia in patients with
77 e robustness and nonperturbing nature of our binder as tyrosination sensor, a live-cell tubulin nanob
80 a universal pY-binding Ab to create a first binder B1 for the pY motif on the pY protein, and then s
81 ainst the B1-pY protein complex for a second binder B2 that recognizes the composite epitope of B1 an
82 neered a series of ultra-high affinity siRNA binders based on the viral protein p19 and developed the
84 flexibility in both the choice of substrate binders (binding positions, scaffold-class) and the E3 l
87 we used a leucine-rich repeat (LRR) protein binder, called a repebody (Rb), that specifically recogn
88 n be summarized as follows: (i) pigments and binders can be detected simultaneously in the same mass
89 nt a new paradigm that high affinity monomer binders can lead to strongly sub-stoichiometric inhibiti
92 shaping utilising high pressure or chemical binders collapses porosity or creates low-density struct
93 comprised of aggregate (rocks) mixed with a binder composed of high-boiling petroleum-derived compou
94 ram of cellulose, yielding a volume-averaged binder concentration of up to 760muM within the resultin
96 ntal results of fatigue behavior of ultralow-binder-content inorganic-organic hybrid (IOH) based on l
98 r to continue their non-iron-based phosphate binders (control) in a multicentre, open-label, parallel
100 trategy of the forger: Dating of the organic binder delivers clear evidence of a post-1950 creation o
102 polymers, serving as the artificial protein binders, demonstrate good potential to overcome these dr
104 ental impacts arising from the production of binders derived from several of the most commonly invest
105 physical characterization of a subset of the binder designs showed that they are extremely stable and
107 is optimized to avoid undesired reduction in binder diversity and enrichment of non-specific binders
109 iameter less than 10 mum), three consecutive binder droplets were observed to coalesce to form large
111 otors on opposite ends of a stiff rod to two binders, each representing 16 motors, reduced force gene
112 the significant studies on active materials, binders, electrode designs based on various templates, p
114 affinity to albumin and the tightest albumin binder exhibited the highest activity improvement in mus
115 -interacting proteins, all known cardiolipin binders, fall into two groups, those involved in ATP pro
116 we develop the Fluorescein Arsenical Hairpin Binder- (FlAsH-) based FRET in vivo approach to study DV
117 ograins within a non-conducting polymer as a binder) followed by compression through a roller-pair, a
118 known as MXenes, can be used as a conductive binder for silicon electrodes produced by a simple and s
124 one-step approach to prepare a low-cost and binder free MoS(2)-pencil graphite electrode (i.e., MoS(
125 micelle-enabled self-assembly approach for a binder-free and carbon-based monolithic device, aimed at
127 tive vertical graphene (VG) skeleton forming binder-free arrays for high-efficiency hydrogen evolutio
128 onductive substrate, nanosized thickness and binder-free composition facilitate ionic transport and p
133 challenges for such full-cell LIBs based on binder-free nanostructured electrodes are discussed.
134 and polymers as well as other substrates for binder-free nanostructured electrodes in LIBs are summar
135 hermore, the potential applications of these binder-free nanostructured electrodes in practical full-
136 he membrane is demonstrated to function as a binder-free, high-performance gas diffusion electrode fo
137 rous architecture was prepared and used as a binder-free, low-cost, high-performance anode for lithiu
138 ell as the identification of the best target binders from a batch of aptamer candidates, independent
140 spectrometry peptide sequencing to identify binders from fully randomized synthetic libraries of 10(
141 mpt aimed at distinguishing antibody-antigen binders from non-binders and demonstrates the challenges
142 ophoresis (IFCE) allows selection of protein binders from oligonucleotide libraries in a single step
145 eening cascade and identified the first LANA binders from small, structurally diverse compound librar
147 bodies are especially suited for cases where binder generation via immune libraries fails due to high
151 rching for potent and selective G-quadruplex binders, here we describe a small series of new monohydr
152 he extent of sulfation of the minimal-length binder (hexamer) is relatively modest yet persistent, co
154 f cellulose nanofibrils (CNF) as an adhesive/binder in lignocellulosic-based composite manufacture re
155 igning 87.20% of AR binders and 96.81% of GR binders in a 25% test set using holdout cross-validation
159 of insulating and electrochemically inactive binders in commercial LIB electrodes causes uneven activ
162 strated their utility as selective chromatin binders in living cells by stably expressing eCRs in mou
166 etic non-immunoglobulin customizable protein binders invaluable to basic and applied research, and of
167 ional characterization of the virgin asphalt binder, irradiated asphalt binder, and the water-soluble
168 ractice of starting from the highest potency binder is an ineffective method for discovering active c
169 to the morpholine utility as a kinase hinge binder is its ability to adopt a coplanar conformation w
170 carboxylates, an indicator that the organic binder is not inert and plays a role in the dating strat
172 nzyme digestion of paint layer proteinaceous binders is introduced for faster and more confident iden
173 gions of DNA are vulnerable to attack by DNA binders, it was concluded that the observed double-stran
174 maging technique was used to investigate the binder jetting additive manufacturing (AM) process.
176 anding of underlying physics that govern the binder jetting processes, which will then help in improv
177 rove conductivity and a polymer is used as a binder, leading to a heterogeneous surface film with thi
181 ion of the supramolecular ion conductor as a binder material allows for the creation of stretchable l
182 anic nanoparticles within a flexible polymer binder matrix, the rationally designed artificial SEI no
187 ic PCR with a blocking reagent (minor groove binder [MGB] oligonucleotide blocker) to suppress amplif
188 binding characteristics of DNA minor groove binders (MGBs) is important for the rational design and
189 rapies including those based on minor groove binders (MGBs), such as the diamidines, which have been
190 s show that Vietnamese lacquer was used as a binder, mixed together with linseed oil and pine resins
191 cially available cobalt precursor and Nafion binder mixture coated on a glassy carbon electrode.
193 signatures for lipid and protoporphyrin TSPO binders, molecular classes that likely interact with sep
194 s, namely, a representative DNA minor-groove binder (netropsin) and ligands binding DNA base-pairing
195 iew the signal intensity graph including the binder/non-binder threshold followed by a list of glycan
196 ion of native protein quaternary assemblies (binders/nonbinders) based on statistical potentials.
197 data indicate that, similar to other capsid binders, OBR-5-340 induces thermostability and inhibits
198 ellularly interacts with a dominant negative binder of Beclin-1, known as leucine-rich pentatricopept
199 unds into silicone oil, acting as lipophilic binder of glassy carbon paste electrode, with subsequent
200 nase c-Raf (c-Raf-RBD) is the tightest known binder of KRas, a protein implicated in difficult-to-tre
202 etic analysis revealed that Tmeff2 is a weak binder of PDGFA, and not required for OL differentiation
203 was applied for the characterization of the binders of a historical fresco of the XVI century from t
207 ning (HTS) of a chemical library to identify binders of mircoRNA-15b which is identified as a biomark
208 f screening methods in an effort to discover binders of PrP, including (19)F-observed and saturation
210 myc and analogues presented here, are potent binders of the E-box DNA engaged by Myc for transcriptio
211 evelopment of extremely powerful multivalent binders of the Influenza virus and other viruses, compar
212 PHICS are formed by linking small-molecule binders of the kinase and the target protein, and exhibi
214 perimental screen to identify small-molecule binders of ULK4, and identify several novel scaffolds th
215 ew powerful applications as light-switchable binders of untagged proteins with the temporal and spati
216 sting with a selective and non-selective JH2 binder on the autophosphorylation of wild-type and V617F
217 s the effects of non-calcium-based phosphate binders on intermediate cardiovascular markers, we condu
223 we show, that the small recombinant protein binders (PBs) can be used for this purpose as well, with
225 ed on a thin metal net sheet without using a binder, placed into a filter holder between filter paper
228 idation microcosm, thin films of the asphalt binder produce abundant oil- and water-soluble oxygenate
230 a novel H2A.Z-specific multivalent chromatin binder providing a surprising link between H2A.Z, chromo
231 including Ebola Zaire Target 1, major groove binder real-time-polymerase chain reaction assays, and o
232 two of the most strongly enriched viral RNA binders, restrict SARS-CoV-2 replication in infected cel
233 o-crystal structures of the highest affinity binder reveal a highly preorganized binding site, and an
234 with related structures from 30 initial RAS binders showed binding to a pocket where compounds had b
235 ets (NADEL) effectively sampled the chemical binder space of enzymes with ADP-ribosyltransferase acti
236 LISA methodology was tested using a panel of binders specific to carbonic anhydrase II, with dissocia
237 ssembled ON-switch shows that the engineered binder specifically recognizes the conformational change
238 , F K-edge to study the electrolyte salt and binder stability, and the transition metal L-edges to ga
240 perimental selection approach for generating binders targeting functional sites with large, shape com
241 uctions of MTs stabilized by the taxane-site binders Taxol and zampanolide, and by peloruside, which
242 acterization, show that a2 is a stronger KR2 binder than a1, suggesting that these two motifs may pla
245 n be rescued by using hydrogen-bonding anion binders that attenuate deleterious ion-pairing interacti
246 yl tRNA-binding site and towards synergistic binders that occupy the nascent peptide exit tunnel.
247 , and biocatalysis rely on selective protein binders that specifically capture a protein in a complex
248 lications ranging from the design of protein binders that wrap around their target to the positioning
249 nal intensity graph including the binder/non-binder threshold followed by a list of glycan-binding mo
250 tethers, mechanically binding nano-Si to CMC binder through epoxy ring-opening reaction while stabili
251 predicted peptides to be strong MHC class I binders through direct binding of predicted peptides to
252 ify 9 (JNJ-64326067), a potent and selective binder to aggregated tau with a favorable pharmacokineti
253 re of the soft porous sheets, which act as a binder to improve interlayer packing and load transfer i
255 tio) of novel nanofiber cellulose (NFC) as a binder to provide sufficient adhesion strength to hold t
256 ctric particles to be dispersed in a polymer binder to synthesize printable slurries, and printed fil
258 To validate this approach, we show that binders to a monoclonal antibody are identified in propo
261 der diversity and enrichment of non-specific binders to ensure the best possible selection outcome.
262 We applied pY-TRAP to create highly specific binders to folded Ub-pY59, a rarely studied Ub phosphofo
263 finity-modifying group and optimized albumin binders to maximize the tumor-to-kidney absorbed dose ra
264 re then applied to the discovery of p53-like binders to MDM2, and to a family of 3-19 nM-affinity, al
265 ly demonstrate the potential for alternative binders to mitigate environmental burdens and highlight
267 s demonstrate the ability of TYK2 JH2 domain binders to provide a highly selective alternative to con
268 not support the role of intestinal phosphate binders to reduce cardiovascular risk in patients with C
269 apply this method to stepwise evolve peptide binders to streptavidin, a protein studied for over two
270 s on the 2D compound space, and to infer new binders to the same protein, or to infer new potential t
271 MR finds true inhibitors, as opposed to only binders to the target protein, in early steps of lead co
272 molecule and identify a panel of three novel binders to this membrane protein, one with a dissociatio
273 cal dye FlAsH (fluorescein arsenical hairpin binder) to detect soluble oligomers and mature fibrils f
274 g domains revealed that efficient nucleosome binders use short anchoring alpha helices to bind DNA, w
275 helices to bind DNA, whereas weak nucleosome binders use unstructured regions and/or beta sheets.
277 In situ sampling/extraction of proteinaceous binders using small pieces of a hydrophilic gel, previou
278 cin A in competition with known minor groove binders, UV spectroscopic studies, and electrophoretic a
280 ichment of indel mutations for high-affinity binders was three times that of non-synonymous SNV mutat
282 After a 1- to 3-week washout of phosphate binders, we randomly assigned 162 eligible patients (ser
283 timized affinity-modifying group and albumin binders were combined, and the resulting derivatives wer
286 various affinity-modifying groups or albumin binders were synthesized and evaluated by PET/CT imaging
289 ed from existing classes of DNA minor groove binders, were designed, synthesized, and evaluated for t
290 sidered to be a selectivity filter for A(3)R binders, when it was mutated to glutamic acid or alanine
292 ased reporters armed with a DNA minor groove binder, which monitor DNA-bound NE and CG activity, resp
293 the catalysts with platinum particles on the binder, which separates platinum and acid sites at the n
294 racterization usually requires additives and binders whose contributions are difficult to dissect.
295 ntrance of the pocket than most other capsid binders, whose viral complexes have been studied so far,
296 To address these challenges, polymer latex binders with diverse particle morphologies have been dev
299 s (ZSM-22 and mordenite) and a gamma-alumina binder, with platinum particles controllably deposited e