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1 t and the presence/absence and nature of the binder).
2  materials (i.e., graphite and thermoplastic binder).
3 isting of graphite and thermoplastic polymer binder.
4 requirement for a sufficiently potent target binder.
5  of environmental impacts relative to the PC binder.
6 and how this protein may act as a multi-drug binder.
7 d identified a benzyl amidine based fragment binder.
8 hen hybridized with various levels of CNF as binder.
9  identify PWWP2A as a novel H2A.Z-nucleosome binder.
10 le of a reduction-activated G-quadruplex DNA binder.
11 nt affinities, with Hp 2-2 being the weakest binder.
12 ein that CXXC5 is indeed an unmethylated CpG binder.
13 e effects of solar irradiation on an asphalt binder.
14 were used as electrode materials without any binder.
15 ermeable ionomers as the functional catalyst binder.
16 an be optimized to a selective submicromolar binder.
17 ere redistributed in favor of the best anion binders.
18 etic organic pigments with alkyd and acrylic binders.
19 no change could be detected for low-affinity binders.
20 s of qualitative information-binders and non-binders.
21 as well as guidance for the use of potassium-binders.
22 ce the binding behavior of already promising binders.
23  hominis, which confirmed that these are FMN binders.
24  neither as AMP nor as AICAR or succinyl-ZMP binders.
25 ring, for example, by designing bi-paratopic binders.
26 nostic applications for topology-specific GQ binders.
27 ary phosphate restriction and oral phosphate binders.
28 OFs, Zr-UiO-66, without applying pressure or binders.
29 ith less-conserved regions than known capsid binders.
30  binding, and identified 2,618 high-affinity binders.
31 y intractable fragment hits into more potent binders.
32  other methods may identify a wider range of binders.
33 ngth of high-, medium-, and low-affinity RGD-binders.
34 ss predictions among the native nucleic acid binders.
35 rials, without conductive additives or other binders.
36 PrP is a difficult target for small-molecule binders.
37 agments were progressed to discover improved binders.
38 uld result in effects distinct from ATP site binders.
39 tly attained regardless of the used painting binders.
40 r 3 is more Brr2-selective than the RNA site binder 12.
41                       The reversible S1 site binder, 4-aminobenzamidine (pAB), acted as a classical c
42                                          The binder, a cationic polyelectrolyte, is shown to both fac
43 and genomic imprinting at birth.-Tserga, A., Binder, A.
44 rch for new drug-like selective G-quadruplex binders, a bioinspired design focused on the use of nucl
45 are useful to identify other colchicine site binders, a frequent target of structurally diverse small
46 rom which we identified a high-affinity V(H) binder ab8.
47 g various interacting proteins into covalent binders, achieving specific covalent protein targeting f
48                     We identified a suitable binder additive, methyl cellulose, which offers suitable
49 valent (RC), and irreversible covalent (IRC) binders, affects the degradation of Bruton's Tyrosine Ki
50 ing a yeast display library, we identified a binder against terminal tyrosine of alpha-tubulin, a uni
51  for the generation of conformation-specific binders against labile membrane proteins or protein comp
52 d can be engineered to develop high-affinity binders against specific targets of interest.
53 he translational potential of FMN riboswitch binders against wild-type Gram-negative bacteria.
54 ly obtained after mixing carbon black with a binder agent and water.
55 HT-SELEX rounds and their enrichment in weak binders allows Co-SELECT to detect an evidence for the r
56 ecific molecules containing a target protein binder and an ubiquitin ligase binder connected by a lin
57 llulose enables stronger binding between the binder and macromolecules.
58 dentified the same interactions as known FK1 binder and provide new chemical starting points.
59 es more tightly than the previous best known binder and roughly 36 times more tightly than the design
60 that an indazole would be the stronger hinge binder and would impart increased potency when substitut
61 f accuracy, correctly assigning 87.20% of AR binders and 96.81% of GR binders in a 25% test set using
62 on the isolation of stable and high-affinity binders and catalysts, or on the design of nanomaterials
63 inguishing antibody-antigen binders from non-binders and demonstrates the challenges to address for t
64  being treated with non-iron-based phosphate binders and erythropoiesis-stimulating agents (ESA) to r
65 ergy calculations of qualitative information-binders and non-binders.
66 ch facilitates the identification of diverse binders and the fast ligandability assessment of new tar
67 der to minimize the distance between the two binders and then link the resulting compounds using flex
68 at enhancing the identification of egg-based binders and then validated on fresh and aged model picto
69 1, Lsp1, eIF5A, and eEF2 as RanGTP-dependent binders and thus as export cargoes.
70 ects of lanthanum carbonate (LC; a phosphate binder) and/or nicotinamide (NAM; an inhibitor of active
71   Depending on the composition (carbon type, binder, and composition ratio), TPEs can give excellent
72  solid lubricant mixture of graphene, Aremco binder, and recycled LCO was formulated into a spray wit
73 ormer serves as an energetic initiator and a binder, and the latter is a thickening agent and the oth
74 he virgin asphalt binder, irradiated asphalt binder, and the water-soluble photoproducts.
75 rate hydrate (FC) is an iron-based phosphate binder approved for hyperphosphataemia in patients with
76         Thus, we provide a high-affinity MIF binder as a novel tool to advance MIF-oriented research.
77 e robustness and nonperturbing nature of our binder as tyrosination sensor, a live-cell tubulin nanob
78 d desirable features to develop G-quadruplex binders as safe and effective anticancer agents.
79                                              Binders at this epitope could be useful therapeutically,
80  a universal pY-binding Ab to create a first binder B1 for the pY motif on the pY protein, and then s
81 ainst the B1-pY protein complex for a second binder B2 that recognizes the composite epitope of B1 an
82 neered a series of ultra-high affinity siRNA binders based on the viral protein p19 and developed the
83 ization resulted in 11 new submicromolar KOR binders (best Ki = 90 nM).
84  flexibility in both the choice of substrate binders (binding positions, scaffold-class) and the E3 l
85 velopment of CD4-binding site (CD4bs), HCDR3-binder bnAbs via sequential HIV-1 Env vaccination.
86 iller type, filler particle size, and filler-binder bonding.
87  we used a leucine-rich repeat (LRR) protein binder, called a repebody (Rb), that specifically recogn
88 n be summarized as follows: (i) pigments and binders can be detected simultaneously in the same mass
89 nt a new paradigm that high affinity monomer binders can lead to strongly sub-stoichiometric inhibiti
90                              In addition, no binders, carbon additives or current collectors are adde
91 n choose the criterion for binder versus non-binder classification.
92  shaping utilising high pressure or chemical binders collapses porosity or creates low-density struct
93  comprised of aggregate (rocks) mixed with a binder composed of high-boiling petroleum-derived compou
94 ram of cellulose, yielding a volume-averaged binder concentration of up to 760muM within the resultin
95 arget protein binder and an ubiquitin ligase binder connected by a linker.
96 ntal results of fatigue behavior of ultralow-binder-content inorganic-organic hybrid (IOH) based on l
97           Thus, CXXC5 as an unmethylated CpG binder contributes to E2-mediated gene expressions that
98 r to continue their non-iron-based phosphate binders (control) in a multicentre, open-label, parallel
99      It was concluded that the proteinaceous binder degrades into aromatic amino acids and/or fatty a
100 trategy of the forger: Dating of the organic binder delivers clear evidence of a post-1950 creation o
101                          Out of 12 predicted binders, delphinidin-3-glucoside, cyanidin-3-glucoside,
102  polymers, serving as the artificial protein binders, demonstrate good potential to overcome these dr
103                                 We show that binders derived from most of these alternative cements r
104 ental impacts arising from the production of binders derived from several of the most commonly invest
105 physical characterization of a subset of the binder designs showed that they are extremely stable and
106                           Whereas orthogonal binder discovery methods could yield high-affinity compo
107 is optimized to avoid undesired reduction in binder diversity and enrichment of non-specific binders
108 chnique that captures features of the carbon-binder domain.
109 iameter less than 10 mum), three consecutive binder droplets were observed to coalesce to form large
110 ns are often conducted only on high affinity binders due to conservative data thresholding.
111 otors on opposite ends of a stiff rod to two binders, each representing 16 motors, reduced force gene
112 the significant studies on active materials, binders, electrode designs based on various templates, p
113           Here, we developed a combinatorial binders-enabled selection of CID (COMBINES-CID) method b
114 affinity to albumin and the tightest albumin binder exhibited the highest activity improvement in mus
115 -interacting proteins, all known cardiolipin binders, fall into two groups, those involved in ATP pro
116 we develop the Fluorescein Arsenical Hairpin Binder- (FlAsH-) based FRET in vivo approach to study DV
117 ograins within a non-conducting polymer as a binder) followed by compression through a roller-pair, a
118 known as MXenes, can be used as a conductive binder for silicon electrodes produced by a simple and s
119             The design of aqueous probes and binders for complex, biologically relevant anions presen
120 mal common substructure searches on chemical binders for each target from the ToxCast dataset.
121             The functionality of a subset of binders for each target was also confirmed using immunof
122 air, or pY-TRAP, for in vitro engineering of binders for native pY proteins.
123 creening campaigns to identify potential RNA binders for pharmaceutical intervention.
124  one-step approach to prepare a low-cost and binder free MoS(2)-pencil graphite electrode (i.e., MoS(
125 micelle-enabled self-assembly approach for a binder-free and carbon-based monolithic device, aimed at
126                                         This binder-free and straightforward strategy for electrode p
127 tive vertical graphene (VG) skeleton forming binder-free arrays for high-efficiency hydrogen evolutio
128 onductive substrate, nanosized thickness and binder-free composition facilitate ionic transport and p
129         Thus, nanostructured electrodes with binder-free designs are developed and have numerous adva
130 ergy batteries has driven the development of binder-free electrode architectures.
131 self as a promising strategy for engineering binder-free electrode with endurable performance.
132                          The sensor-based on binder-free Iso-AgNPs showed linearity from 0.1 uM to 4
133  challenges for such full-cell LIBs based on binder-free nanostructured electrodes are discussed.
134 and polymers as well as other substrates for binder-free nanostructured electrodes in LIBs are summar
135 hermore, the potential applications of these binder-free nanostructured electrodes in practical full-
136 he membrane is demonstrated to function as a binder-free, high-performance gas diffusion electrode fo
137 rous architecture was prepared and used as a binder-free, low-cost, high-performance anode for lithiu
138 ell as the identification of the best target binders from a batch of aptamer candidates, independent
139  molecule 1 (ICAM-1), allowing us to predict binders from a specific sequence motif alone.
140  spectrometry peptide sequencing to identify binders from fully randomized synthetic libraries of 10(
141 mpt aimed at distinguishing antibody-antigen binders from non-binders and demonstrates the challenges
142 ophoresis (IFCE) allows selection of protein binders from oligonucleotide libraries in a single step
143 mplement for IFCE-based selection of protein binders from oligonucleotide libraries.
144 cocrystal structures of the highest affinity binders from several classes.
145 eening cascade and identified the first LANA binders from small, structurally diverse compound librar
146           The highest affinity USP11 peptide binder fused to a cellular delivery sequence induced sig
147 bodies are especially suited for cases where binder generation via immune libraries fails due to high
148                        The use of an albumin binder has been shown to improve tumor uptake of prostat
149 degradation, but no validated small-molecule binders have been discovered to date.
150  targeting the ubiquitin system, very few E2 binders have currently been discovered.
151 rching for potent and selective G-quadruplex binders, here we describe a small series of new monohydr
152 he extent of sulfation of the minimal-length binder (hexamer) is relatively modest yet persistent, co
153  followed by two rounds of phage display and binder identification by ELISA.
154 f cellulose nanofibrils (CNF) as an adhesive/binder in lignocellulosic-based composite manufacture re
155 igning 87.20% of AR binders and 96.81% of GR binders in a 25% test set using holdout cross-validation
156 calin family interacts with engineered hRBP4 binders in a small molecule-dependent manner.
157 r use to make stimuli-responsive gels and as binders in battery electrodes.
158 nd FGF23 reduction with intestinal phosphate binders in CKD.
159 of insulating and electrochemically inactive binders in commercial LIB electrodes causes uneven activ
160           An X-ray structure of one of these binders in complex with 14-3-3sigma is determined, illus
161 plored extensively for the identification of binders in early drug-discovery efforts.
162 strated their utility as selective chromatin binders in living cells by stably expressing eCRs in mou
163  that are employed as membranes and catalyst binders in membrane-electrode assemblies.
164  use of carbon-based additives and polymeric binders in the electrode composition.
165  not 5fTHF) is the predominant physiological binder/inhibitor of SHMT.
166 etic non-immunoglobulin customizable protein binders invaluable to basic and applied research, and of
167 ional characterization of the virgin asphalt binder, irradiated asphalt binder, and the water-soluble
168 ractice of starting from the highest potency binder is an ineffective method for discovering active c
169  to the morpholine utility as a kinase hinge binder is its ability to adopt a coplanar conformation w
170  carboxylates, an indicator that the organic binder is not inert and plays a role in the dating strat
171 sulfide (MoS2 ) nanoassemblies and polymeric binder is reported.
172 nzyme digestion of paint layer proteinaceous binders is introduced for faster and more confident iden
173 gions of DNA are vulnerable to attack by DNA binders, it was concluded that the observed double-stran
174 maging technique was used to investigate the binder jetting additive manufacturing (AM) process.
175                                 A commercial binder jetting printer with droplet-on-demand ink-jet pr
176 anding of underlying physics that govern the binder jetting processes, which will then help in improv
177 rove conductivity and a polymer is used as a binder, leading to a heterogeneous surface film with thi
178                                        Thin, binder-less zeolite NaX laminates, with thicknesses rang
179 s of weight percent loading in water without binder-like additives.
180 n ethanol method with minimized catalyst and binder loadings.
181 ion of the supramolecular ion conductor as a binder material allows for the creation of stretchable l
182 anic nanoparticles within a flexible polymer binder matrix, the rationally designed artificial SEI no
183 ertainty in their detachment from the carbon/binder matrix.
184                  Macrocyclization of a known binder may stabilize its bioactive conformation and impr
185          Furthermore, we show how allosteric binders may overcome the beta-catenin side effects assoc
186                           Among irreversible binders, methyl beta-(3,4-dihydroxyphenyl)-beta-(2-carbo
187 ic PCR with a blocking reagent (minor groove binder [MGB] oligonucleotide blocker) to suppress amplif
188  binding characteristics of DNA minor groove binders (MGBs) is important for the rational design and
189 rapies including those based on minor groove binders (MGBs), such as the diamidines, which have been
190 s show that Vietnamese lacquer was used as a binder, mixed together with linseed oil and pine resins
191 cially available cobalt precursor and Nafion binder mixture coated on a glassy carbon electrode.
192        Using statistical mechanics, a random-binder model without fitting parameters, with genomic DN
193 signatures for lipid and protoporphyrin TSPO binders, molecular classes that likely interact with sep
194 s, namely, a representative DNA minor-groove binder (netropsin) and ligands binding DNA base-pairing
195 iew the signal intensity graph including the binder/non-binder threshold followed by a list of glycan
196 ion of native protein quaternary assemblies (binders/nonbinders) based on statistical potentials.
197  data indicate that, similar to other capsid binders, OBR-5-340 induces thermostability and inhibits
198 ellularly interacts with a dominant negative binder of Beclin-1, known as leucine-rich pentatricopept
199 unds into silicone oil, acting as lipophilic binder of glassy carbon paste electrode, with subsequent
200 nase c-Raf (c-Raf-RBD) is the tightest known binder of KRas, a protein implicated in difficult-to-tre
201 molecule DPFp8, a previously identified lead binder of MALAT1.
202 etic analysis revealed that Tmeff2 is a weak binder of PDGFA, and not required for OL differentiation
203  was applied for the characterization of the binders of a historical fresco of the XVI century from t
204            The occurrence of various protein binders of animal origin was easily and reliably ascerta
205 ue was used to make potent di- and trivalent binders of ASGPR.
206 ch motors were the best force generators and binders of filaments.
207 ning (HTS) of a chemical library to identify binders of mircoRNA-15b which is identified as a biomark
208 f screening methods in an effort to discover binders of PrP, including (19)F-observed and saturation
209 ence and suggests possibilities for some non-binders of the annotated regions.
210 myc and analogues presented here, are potent binders of the E-box DNA engaged by Myc for transcriptio
211 evelopment of extremely powerful multivalent binders of the Influenza virus and other viruses, compar
212   PHICS are formed by linking small-molecule binders of the kinase and the target protein, and exhibi
213             We generalized CARPID to explore binders of the lncRNAs DANCR and MALAT1, revealing the m
214 perimental screen to identify small-molecule binders of ULK4, and identify several novel scaffolds th
215 ew powerful applications as light-switchable binders of untagged proteins with the temporal and spati
216 sting with a selective and non-selective JH2 binder on the autophosphorylation of wild-type and V617F
217 s the effects of non-calcium-based phosphate binders on intermediate cardiovascular markers, we condu
218                                      Albumin binder optimization showed that (68)Ga-HTK03055 and (68)
219 controllably deposited either on the alumina binder or inside the zeolite crystals.
220 -disturbing 3D structure also affects weaker binders ( P((Cl/Na)) = 2.1, P((Cl/NO(3))) = 2.5).
221 opherin-beta Kap123, one of the ZMP-specific binders, partially rescued AICAR toxicity.
222            We evaluated use of the potassium binder patiromer to allow more persistent use of spirono
223  we show, that the small recombinant protein binders (PBs) can be used for this purpose as well, with
224          Fatigue damage mostly occurs in the binder phase, followed by rapid cleavage-like failure.
225 ed on a thin metal net sheet without using a binder, placed into a filter holder between filter paper
226                 Unlike the Abd series of RAS binders, PPIN-1 and PPIN-2 compounds were not competed b
227                    A large amount of polymer binder present in composite films results in a sizable l
228 idation microcosm, thin films of the asphalt binder produce abundant oil- and water-soluble oxygenate
229                               Designed Bfl-1 binders provide reagents for cellular profiling and lead
230 a novel H2A.Z-specific multivalent chromatin binder providing a surprising link between H2A.Z, chromo
231 including Ebola Zaire Target 1, major groove binder real-time-polymerase chain reaction assays, and o
232  two of the most strongly enriched viral RNA binders, restrict SARS-CoV-2 replication in infected cel
233 o-crystal structures of the highest affinity binder reveal a highly preorganized binding site, and an
234  with related structures from 30 initial RAS binders showed binding to a pocket where compounds had b
235 ets (NADEL) effectively sampled the chemical binder space of enzymes with ADP-ribosyltransferase acti
236 LISA methodology was tested using a panel of binders specific to carbonic anhydrase II, with dissocia
237 ssembled ON-switch shows that the engineered binder specifically recognizes the conformational change
238 , F K-edge to study the electrolyte salt and binder stability, and the transition metal L-edges to ga
239          These include L17 and L17-dependent binders, suggesting that structural block 3 of the subun
240 perimental selection approach for generating binders targeting functional sites with large, shape com
241 uctions of MTs stabilized by the taxane-site binders Taxol and zampanolide, and by peloruside, which
242 acterization, show that a2 is a stronger KR2 binder than a1, suggesting that these two motifs may pla
243 ver an order of magnitude more unique MHC-II binders than comparable approaches.
244 ock are less variable in geometry for strong binders than for low-affinity peptides.
245 n be rescued by using hydrogen-bonding anion binders that attenuate deleterious ion-pairing interacti
246 yl tRNA-binding site and towards synergistic binders that occupy the nascent peptide exit tunnel.
247 , and biocatalysis rely on selective protein binders that specifically capture a protein in a complex
248 lications ranging from the design of protein binders that wrap around their target to the positioning
249 nal intensity graph including the binder/non-binder threshold followed by a list of glycan-binding mo
250 tethers, mechanically binding nano-Si to CMC binder through epoxy ring-opening reaction while stabili
251  predicted peptides to be strong MHC class I binders through direct binding of predicted peptides to
252 ify 9 (JNJ-64326067), a potent and selective binder to aggregated tau with a favorable pharmacokineti
253 re of the soft porous sheets, which act as a binder to improve interlayer packing and load transfer i
254          Using SHG, we identified a fragment binder to KRas(G12D) and used (1)H (15)N transverse rela
255 tio) of novel nanofiber cellulose (NFC) as a binder to provide sufficient adhesion strength to hold t
256 ctric particles to be dispersed in a polymer binder to synthesize printable slurries, and printed fil
257 f 3-19 nM-affinity, alpha/beta-peptide-based binders to 14-3-3.
258      To validate this approach, we show that binders to a monoclonal antibody are identified in propo
259 tifs and demonstrated its ability to isolate binders to a wide panel of antigens.
260 is unlike any structurally characterized FMN binders to date.
261 der diversity and enrichment of non-specific binders to ensure the best possible selection outcome.
262 We applied pY-TRAP to create highly specific binders to folded Ub-pY59, a rarely studied Ub phosphofo
263 finity-modifying group and optimized albumin binders to maximize the tumor-to-kidney absorbed dose ra
264 re then applied to the discovery of p53-like binders to MDM2, and to a family of 3-19 nM-affinity, al
265 ly demonstrate the potential for alternative binders to mitigate environmental burdens and highlight
266  method for engineering sequence-specific Ab binders to native pY proteins.
267 s demonstrate the ability of TYK2 JH2 domain binders to provide a highly selective alternative to con
268 not support the role of intestinal phosphate binders to reduce cardiovascular risk in patients with C
269 apply this method to stepwise evolve peptide binders to streptavidin, a protein studied for over two
270 s on the 2D compound space, and to infer new binders to the same protein, or to infer new potential t
271 MR finds true inhibitors, as opposed to only binders to the target protein, in early steps of lead co
272 molecule and identify a panel of three novel binders to this membrane protein, one with a dissociatio
273 cal dye FlAsH (fluorescein arsenical hairpin binder) to detect soluble oligomers and mature fibrils f
274 g domains revealed that efficient nucleosome binders use short anchoring alpha helices to bind DNA, w
275 helices to bind DNA, whereas weak nucleosome binders use unstructured regions and/or beta sheets.
276 lower affinity than FMC63, the high-affinity binder used in many clinical studies(1-4).
277 In situ sampling/extraction of proteinaceous binders using small pieces of a hydrophilic gel, previou
278 cin A in competition with known minor groove binders, UV spectroscopic studies, and electrophoretic a
279 complete, users can choose the criterion for binder versus non-binder classification.
280 ichment of indel mutations for high-affinity binders was three times that of non-synonymous SNV mutat
281            To enable computational design of binders, we developed a unit of protein structure-a van
282    After a 1- to 3-week washout of phosphate binders, we randomly assigned 162 eligible patients (ser
283 timized affinity-modifying group and albumin binders were combined, and the resulting derivatives wer
284                         Several potent EPAC1 binders were identified including 25g, 25q, 25n, 25u, 25
285                 Notably, 37 of 41 identified binders were inhibitory.
286 various affinity-modifying groups or albumin binders were synthesized and evaluated by PET/CT imaging
287                     Subsequently, identified binders were tested for function as third generation Chi
288              Furthermore, the top-performing binders were tested in immunoprecipitation followed by M
289 ed from existing classes of DNA minor groove binders, were designed, synthesized, and evaluated for t
290 sidered to be a selectivity filter for A(3)R binders, when it was mutated to glutamic acid or alanine
291 e latter is a thickening agent and the other binder, which can form a gel.
292 ased reporters armed with a DNA minor groove binder, which monitor DNA-bound NE and CG activity, resp
293 the catalysts with platinum particles on the binder, which separates platinum and acid sites at the n
294 racterization usually requires additives and binders whose contributions are difficult to dissect.
295 ntrance of the pocket than most other capsid binders, whose viral complexes have been studied so far,
296   To address these challenges, polymer latex binders with diverse particle morphologies have been dev
297 t facilitates the detection of low abundance binders with high specificity and sensitivity.
298 ostructures to design efficient cementitious binders with targeted properties.
299 s (ZSM-22 and mordenite) and a gamma-alumina binder, with platinum particles controllably deposited e
300  fragments and screening for target-specific binders within days.

 
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