ライフサイエンスコーパス: bindin

1 e variation in the F-lectin domains of sperm bindin.

2 drift created the polymorphisms observed in bindin.

3 d, likely as a result of an acrosome lacking Bindin.

4 ombinant Strongylocentrotus purpuratus sperm bindin and a recombinant fragment of the putative egg bi

5 d by many observations in vivo and in vitro, bindin and the putative egg receptor display a specific

6 he interaction of the sperm adhesive protein,bindin, and a complementary receptor on the egg surface,

7 Bindin, as well as various parthenogenic agents known to

8 displays species-specific sperm adhesion and bindin-binding activity.

9 Males also express alternatively spliced bindin cDNAs with one to five repeats, but typically tra

10 nd divergence are radically different in the bindin coding and intron regions.

11 ion from neutrality has been detected in the bindin coding region and suggested in the intron, indica

12 Positive selection is detected in the bindin coding region.

13 Sperm lacking Bindin do not bind to nor fertilize eggs at even high co

14 Cys3His repeats) that are thought to be zinc-bindin domains.

15 clone the species-specific egg receptor for bindin, EBR1, from Strongylocentrotus franciscanus (Sf)

16 The sperm gene bindin encodes a gamete recognition protein, which plays

17 We studied bindin evolution in the pantropical sea urchin Diadema,

18 The mode of bindin evolution varies across sea urchin genera studied

19 ympatric species tend to be those with rapid bindin evolution.

20 ; they happen to be those with slow rates of bindin evolution.

21 In seven species of Diadema, bindin evolves under purifying selection, more slowly th

22 ctioning adults, support the contention that Bindin functions are limited to species-specific sperm-e

23 There is only one bindin gene in C. gigas, which can possess 1-5 tandem F-

24 on is not present in the one F-lectin repeat bindin gene.

25 Two bindin genes were sequenced to learn more about bindin i

26 We report on how the sperm bindin genotype influences reproductive success under na

27 cy and spawning density determines how sperm bindin genotype influences reproductive success.

28 Eggs select sperm with a bindin genotype similar to their own, suggesting strong

29 ng discrimination on the basis of the males' bindin genotype.

30 Oyster bindins have a conserved N-terminal region followed by o

31 Bindin in sea urchin sperm is one such gamete interactio

32 Bindin in the East Pacific D. mexicanum, the West Atlant

33 involvement of diversifying selection in the bindin intron evolution more data combining population g

34 ng the possible functional importance of the bindin intron variability.

35 the action of diversifying selection in the bindin intron.

36 din genes were sequenced to learn more about bindin introns.

37 ve selection at gamete recognition loci like bindin involves strong selection within species on mate

38 The putative functional unit of bindin is a fucose lectin (F-lectin) domain that is stru

39 quence variation observed in S. franciscanus bindin is a result of neutral evolution.

40 observed in the 5' region of S. franciscanus bindin is a result of neutral evolution.

41 Oyster bindin is a single-copy gene encoding a diversity of pro

42 Bindin is a sperm protein that mediates attachment and m

43 Bindin is a sperm recognition protein that mediates spec

44 We recently showed that Bindin is essential for fertilization by use of Cas9 tar

45 conclude that the evolutionary divergence of Bindin is not constrained by any other biological roles.

46 We found that Diadema bindin is structurally similar to that of other genera,

47 The region of the bindin locus examined was found to be polymorphic with 1

48 ir region located at the 5' end of the sperm bindin locus in 134 adult red sea urchins (Strongylocent

49 udied nucleotide variability in the complete bindin locus, including two exons and one intron, in the

50 Variation in the evolutionary rates of bindin may reflect historic differences in sperm availab

51 he sea urchin genus Echinometra, the protein bindin mediates sperm attachment to eggs, evolves quickl

52 These data, and the observation that Bindin-minus embryos develop normally and metamorphose i

53 pe and Bindin-minus sperm identified is that Bindin-minus sperm have a slightly shorter head, likely

54 phenotypic differences between wildtype and Bindin-minus sperm identified is that Bindin-minus sperm

55 Here we show phenotypic details of Bindin-minus sperm.

56 splicing can alter the number of repeats per bindin mRNA.

57 The level of the bindin nucleotide diversity is close for S. intermedius

58 Only bindin of the recently rediscovered D. clarki shows evid

59 gigas oyster sperm acrosome react a ring of bindin protein is exposed that bonds the sperm to the eg

60 on followed by eight and one-half tandem egg bindin receptor (EBR) repeats that share 88% identity wi

61 Thus,the species-specific domains of egg bindin receptor 1 (EBR1) from both species function as t

62 d a recombinant fragment of the putative egg bindin receptor of the same species was measured in vitr

63 oxidase subunit I and nuclear gene encoding bindin, respectively, which is significantly below avera

64 We have also analyzed all available bindin sequences for two other sea urchin species, S. pa

65 The results show that the bindin sequences from the two forms of S. intermedius ar

66 overlap in the Indo-West Pacific, yet their bindins show no evidence of positive selection, possibly

67 oyster Crassostrea gigas contain the protein bindin that bonds sperm to egg during fertilization.

68 dase subunit I and the nuclear gene encoding bindin to evaluate the possibility of cryptic species wi

69 forms exhibit slightly different patterns in bindin variability.

70 Additional bindin variants result from recombination in an intron i

71 g, and recombination can create thousands of bindin variants within C. gigas.

72 evolution of the gamete recognition protein bindin, which is critical to reproductive isolation.