ライフサイエンスコーパス: binding experiment

1 was validated by immunoblotting and in vitro binding experiments.

2 inely used as probes for conducting in vitro binding experiments.

3 was shown by neutralisation and micro-array binding experiments.

4 onfirmed by surface plasmon resonance direct binding experiments.

5 ng GABAB receptors and performed competition binding experiments.

6 ed through guanosine 5'-O-(thiotriphosphate) binding experiments.

7 mersome shell, as proven by selective lectin binding experiments.

8 odynamic, biosensing, or other thermodynamic binding experiments.

9 These conclusions were confirmed by coenzyme binding experiments.

10 ced by enzymatic assays and antigen-antibody binding experiments.

11 to get the most out of valuable reagents in binding experiments.

12 zed by enzyme inhibition and NMR and Biacore binding experiments.

13 interpretation and design of protein-ligand binding experiments.

14 and E2F was also supported by independent TF binding experiments.

15 ociation constants were determined in direct binding experiments.

16 by sequence patterns discovered by in vitro binding experiments.

17 fibril assembly using chromatography and dye-binding experiments.

18 y two conceptually different sets of tweezer binding experiments.

19 fully displaced radiolabeled vasopressin in binding experiments.

20 n by using in situ hybridization and in situ binding experiments.

21 to be -6.5 kcal mol(-1) at pH 4.9 by vesicle binding experiments.

22 oscopy assay for saturation- and competition-binding experiments.

23 finity for neuropilin-1 based on competition binding experiments.

24 our three-dimensional structure and affinity binding experiments.

25 ed crRNAs using RNP stability and DNA target binding experiments.

26 ceptors/channels/transporters in radioligand binding experiments.

27 brane-based [(3)H]DPCPX and [(35)S]GTPgammaS binding experiments.

28 ll as NAM affinities with [(3)H]methoxy-PEPy binding experiments.

29 nding of RcoLS20, as seen in competitive DNA binding experiments.

30 of in vitro biochemical analyses and in vivo binding experiments.

31 518 using small-angle neutron scattering and binding experiments.

32 Anion binding experiments ((1)H NMR titrations, ESI-MS) reveal

33 n [(35)S]-tert-butylbicyclophosphorothionate binding experiments, (2) in electrophysiological experim

34 In equilibrium and kinetic binding experiments [(3)H]RO6957022 showed high affinity

35 ere also synthesized and used in competition binding experiments against [(125)I-Tyr(4)]BBN in GRPR-p

36 Competition binding experiments against [(125)I-Tyr(4)]BBN were cond

37 Among the best candidates, in vitro binding experiments allowed identification of three nove

38 Significantly, the equilibrium binding experiments also indicate that, regardless of wh

39 ANS binding experiments and analysis of the CD data show tha

40 This conclusion was further supported by binding experiments and assessment of membrane lipid pac

41 We also use a combination of in vitro binding experiments and bioinformatics analysis to redef

42 blotting, co-immunoprecipitation, and myosin-binding experiments and cell migration assays, we show h

43 DNA binding experiments and cell-based transcription studies

44 d control cells was assessed in cell culture binding experiments and compared with that of microbubbl

45 experimentally validated by hsc-70 endosomal binding experiments and endosomal microautophagy assays.

46 Binding experiments and functional assays identified MD2

47 ding kinetics, without the need for repeated binding experiments and immobilizing the molecules.

48 nR in two crystal forms together with ligand binding experiments and in vivo studies.

49 Binding experiments and Laurdan generalized-polarization

50 Ligand blot analysis, C3 binding experiments and opsonophagocytosis assays identi

51 In vitro DNA-binding experiments and structural prediction show that

52 RBPmap was tested on high-throughput RNA-binding experiments and was proved to be highly accurate

53 ctroscopy and saturation transfer difference binding experiments) and ultimate hit validation by isot

54 In silico docking analysis, competition binding experiments, and downstream assays were used to

55 ere, we used molecular dynamics, microtubule-binding experiments, and live-cell microscopy, revealing

56 transfer (BRET)-based saturation and kinetic binding experiments, as well as a high specific to nonsp

57 In competition binding experiments, atrial natriuretic peptide and brai

58 extensive nucleotide sequences identified in binding experiments based on their selection by a TF.

59 In chromatin binding experiments, bexarotene increased the occupancy

60 However, our SRAP-RNA binding experiments, both in vitro with recombinant prot

61 y distinguished from full-length channels in binding experiments but do not form functional channels.

62 mized for analysis of modular domain-peptide binding experiments but the platform offers a broader ap

63 Real time binding experiments by surface plasmon resonance spectro

64 Real time binding experiments by surface plasmon resonance spectro

65 Real time binding experiments by surface plasmon resonance spectro

66 Structural analyses and binding experiments comparing the wild-type furin propep

67 ity and 1-anilinonaphthalene-8-sulfonic acid-binding experiments, comparing original BEAT, mutated BE

68 Both direct and displacement binding experiments concurred to define the following bi

69 Transient-state glucose binding experiments conducted in the presence of increas

70 Ab binding experiments conducted with an enzymatically degl

71 [(3)H]NMS ([(3)H]N-methylscopolamine) binding experiments confirm that LY2119620 does not comp

72 dent synaptosomal DA release and radioligand binding experiments confirmed correct expression and fun

73 Equilibrium binding experiments confirmed that C-terminal peptides d

74 In vitro binding experiments confirmed that CMG and/or Mcm2-7 had

75 In vitro binding experiments confirmed that recombinant DbpA prot

76 Equilibrium binding experiments confirmed that the truncated protein

77 Saturation binding experiments demonstrate reduced affinity of the

78 Radioligand binding experiments demonstrate that mutations in this r

79 ally, dynamic light scattering and gel shift binding experiments demonstrate that the ED interface pl

80 Binding experiments demonstrate that the Necl proteins p

81 These binding experiments demonstrate the potential of fluores

82 Molecular docking and TR-FRET GR competitive binding experiments demonstrated that ASI could bind to

83 ever, our immunoprecipitation RT-PCR and RNA binding experiments demonstrated that IRP1, but not IRP2

84 Collagen binding experiments demonstrated that PP favors the form

85 DNA binding experiments demonstrated that PU.1 itself and El

86 Electron microscopy and antibody binding experiments demonstrated that the designed nanop

87 Binding experiments demonstrated that the materials had

88 Solution binding experiments demonstrated that the transmembrane

89 Thus, direct binding experiments, dependence on heparan sulfate, and

90 Using binding experiments, electrophysiology and x-ray crystal

91 Erythrocyte binding experiments elucidated essential glycan contact

92 Competition binding experiments employing [3H]colchicine and purifie

93 In a competitive binding experiment, EpCAM aptamer generated a staining p

94 Here, we use 456 binding experiments for 119 regulators and 84 chromatin

95 Binding experiments for a model system of carbonic anhyd

96 well with affinities measured in radioligand binding experiments for both PAMs and NAMs with diverse

97 report crystallographic analyses and ligand-binding experiments for KAI2 recognition of karrikins.

98 We performed new binding experiments for p53 mutants and used DECOD to id

99 Binding experiments for TATA spacer relative to ATAT sho

100 Surprisingly, equilibrium binding experiments found that the ligand specificity of

101 the DNA binding affinities, and competition binding experiments further characterized the nature of

102 ift assays, together with ligand competition binding experiments, have demonstrated the inability of

103 In direct-binding experiments, HCV helicase bound DNA weakly at hi

104 Similar binding experiments identified a leucine-rich repeat wit

105 Glutathione S-transferase binding experiments identified an internal region of PIS

106 s are typically determined using association binding experiments in competition with radiolabelled pr

107 ds the design and critical interpretation of binding experiments in general.

108 Moreover, binding experiments in mammalian cells show that the mut

109 Binding experiments in solution also confirm that one GN

110 (3)H]33 at the M2R, for instance, saturation binding experiments in the presence of the allosteric MR

111 Here we perform quantitative binding experiments in vitro to determine the ligand req

112 d dopamine transporter (DAT)) in competitive binding experiments in vitro using cloned human transpor

113 ty of the mutant proteins is also evident in binding experiments in vivo.

114 Moreover, binding experiments in which one ligand was added after

115 In vitro and ex vivo autoradiography binding experiments in Wistar and in mGluR2 knockout and

116 Genome-wide binding experiments in zld mutants showed variable effec

117 cell surface levels of TMEM16A and cellular binding experiments indicate CLCA1 engages TMEM16A on th

118 rlin(S518D) adopt a closed conformation, but binding experiments indicate that a significant fraction

119 Genome-wide expression analyses and binding experiments indicate that Brg1 specifically coor

120 However, results of membrane binding experiments indicate that covalent linkage of th

121 Binding experiments indicate that neither SKP1 (S-phase

122 In fact, kinetic and binding experiments indicate that removal of the E-hook

123 Radiolabeled galactose saturation binding experiments indicate that, like LeuT, vSGLT can

124 Kinetic binding experiments indicated a simple one-step binding

125 Heterologous competition-binding experiments indicated that Cry1Ea does not share

126 Phylogenetic analysis and ribosome binding experiments indicated that the MBD interacts wit

127 Competitive binding experiments indicated that the radiolabeled pept

128 at the interface between BBS2 and BBS9, and binding experiments indicated that this mutation disrupt

129 se observations, in combination with surface binding experiments, indicated that trypsin indirectly a

130 dictions by transport kinetics and substrate-binding experiments, integrating the data on this single

131 fraction and a beta-glucan were monitored by binding experiments, ITC and DLS.

132 re reagents, but flaws in the design of many binding experiments limit the information obtained.

133 Results from dissociation and saturation binding experiments (M(2)R) in the presence of allosteri

134 Nonetheless, in direct binding experiments, Mg(2+) replaced three Ca(2+) sites

135 Fluorescence-monitored binding experiments of activator of thyroid hormone and

136 Binding experiments on rat brain membranes and the purif

137 modulator binding modes through radioligand binding experiments on receptor mutants designed, on the

138 with C only, surface plasmon resonance (SPR) binding experiments on the immobilized control antibody,

139 m-exchange, solution scattering data and DNA-binding experiments, our studies reveal a light-sensitiv

140 enesis, nuclear magnetic resonance-monitored binding experiments performed for both H402 and Y402 var

141 Substrate binding experiments performed on purified MdtM demonstra

142 , and fluorescence resonance energy transfer binding experiments performed under equilibrium and kine

143 Grafted antibody binding experiments, performed under stringent condition

144 ronic acids were investigated, and (31)P NMR binding experiments predicted strong hydrogen-bonding ab

145 In vitro binding experiments presented here show that histone ace

146 Additional SAXS, DXMS, and dsRNA-binding experiments presented here support a model of co

147 Furthermore, real-time binding experiments provide no evidence for a more exten

148 Other binding experiments provided evidence for a conformation

149 In vitro binding experiments reveal a direct, robust interaction

150 Ligand-binding experiments reveal a much greater fraction of N5

151 Consistent with this model our in vitro binding experiments reveal optimal assembly of two wild-

152 Quantitative binding experiments revealed a 9 mum dissociation consta

153 Surface plasmon resonance binding experiments revealed binding and dissociation of

154 The anion binding experiments revealed interesting difference in t

155 In vitro protein-protein binding experiments revealed that >65% of these TF pairs

156 Binding experiments revealed that a subset of the BKV mu

157 A series of in vitro DNA binding experiments revealed that POU1F1 binds to multip

158 Furthermore, membrane-binding experiments revealed that the basic linker regio

159 NMR ssDNA-binding experiments revealed that the interaction with r

160 In vitro binding experiments revealed that the RNA-recognition mo

161 Ligand binding experiments revealed that the S186F protein had

162 Gel filtration and biosensor binding experiments revealed that, unlike host FcgammaRs

163 D) and analyzed its selectivity profile; our binding experiments revealed the LBD preference for l-Gl

164 Modeling and binding experiments revealed these conformations to be p

165 Binding experiments show that alpha-COP and beta'-COP ha

166 Finally, DNA binding experiments show that CasA is essential for bind

167 Direct binding experiments show that CDK phosphorylation specif

168 ob1 is essential for optimal growth, and RNA binding experiments show that Dim2 increases Nob1 RNA af

169 Our in vitro binding experiments show that DNA-binding/dimerization d

170 Separate kinetic and binding experiments show that hTdp1 has a preference for

171 Moreover, binding experiments show that K(+) (but not Na(+)) incre

172 In vitro binding experiments show that MSP promotes oocyte mitoge

173 re, de novo Rosetta modeling and competitive binding experiments show that the acidic tip of the E. c

174 Binding experiments show that the affinity of the E2b co

175 DNA-binding experiments show that the Ml proteins studied bi

176 Thermodynamic binding experiments show that the MLL1 Win peptide is pr

177 Ligand-binding experiments showed a good binding affinity betwe

178 increase the rate of ADP release; and direct binding experiments showed osmotic pressure to correspon

179 Binding experiments showed that a Y315A mutation alone s

180 The results of binding experiments showed that after chronic morphine t

181 Equilibrium metal binding experiments showed that AntR binds 2 equivalents

182 interaction assays in live cells and in situ binding experiments showed that Atgl and its protein act

183 Competitive binding experiments showed that Mmp-8 and Mmp-9 share bi

184 However, in vitro binding experiments showed that mutant ICP27 was able to

185 In vitro DNA binding experiments showed that recombinant N-ATF6 beta

186 Binding experiments showed that several AMC compounds ha

187 Competition DNA binding experiments showed that the 5' and central regio

188 However, in vitro binding experiments showed that the H4 mutant proteins b

189 Binding experiments showed that the polymorphic OGG1 bin

190 Drug resistance profiling and drug binding experiments showed that the presence of both Ebr

191 In vitro binding experiments showed that the strength of the inte

192 In vitro binding experiments showed that this hydrophobic patch i

193 f surface plasmon resonance-based, real-time binding experiments showed that while both proteins have

194 MHC-I heavy chain, consistent with in vitro binding experiments showing significantly reduced comple

195 The results of competitive binding experiments suggest that a common adhesin recogn

196 Docking and binding experiments suggest that Phe31 of ELA may bind t

197 Solid phase binding experiments suggest that the unstructured N-term

198 Fluorescence anisotropy competition binding experiments suggest that TWINKLE has more than o

199 Competitive binding experiments suggest that Zn and Cd share the sam

200 Inhibition and direct binding experiments suggest that, during the first half-

201 Mixed binding experiments suggested that gelatin, fibronectin,

202 Additionally, in vitro binding experiments supported the notion that the C term

203 We find that in both saturation and kinetic-binding experiments, the Org 27569 and PSNCBAM-1 appeare

204 In saturation binding experiments, the three radioligands exhibited di

205 ral specificity in surface plasmon resonance binding experiments: The L-protein ligand bound only to

206 lography, molecular dynamics simulations and binding experiments to characterize the protocadherin 15

207 ssion profiling, and microfluidics-based DNA binding experiments to determine the direct and indirect

208 5-trisphosphate accumulation and radioligand binding experiments to determine the impact of receptor

209 Mathematical modeling of EGF-binding experiments to different conformational mutants

210 valuate the feasibility of using competition binding experiments to identify specific lipid-protein i

211 and antibodies to HSPGs were used in in situ binding experiments to identify which HSPGs bound CXCL8.

212 ing complex antibody mixtures and in antigen-binding experiments to understand the contribution of do

213 study uses theory, as well as simulations of binding experiments, to test the validity of the three i

214 RNA binding experiments together with genome editing demonst

215 In competition binding experiments two derivatives (13 and 14) emerged

216 NADH in these preparations, we conducted the binding experiments under anoxic conditions in a special

217 Binding experiments under conditions at which hCXCL1 exi

218 Radioligand binding experiments using [(3)H]MPEP revealed that these

219 Equilibrium binding experiments using a judiciously chosen panel of

220 Equilibrium binding experiments using a panel of well-characterized

221 Competitive binding experiments using a series of ligands including

222 Previous in vitro binding experiments using bacterially expressed HDAg sho

223 me flow cytometry and competition inhibition binding experiments using cell surface CD16a.

224 Detailed binding experiments using cells expressing ALK or the re

225 binding in living HEK293 cells, competition binding experiments using commercially available SMO lig

226 PSMA targeting was analyzed in vitro by cell-binding experiments using flow cytometry, autoradiograph

227 DNA binding experiments using gel-shift and ChIP assays demo

228 Binding experiments using protein fluorescence confirm t

229 ymogens in a systematic manner, we performed binding experiments using recombinant proelastases CELA2

230 Neutral-sugar analysis and lectin binding experiments using succinylated concanavalin A, a

231 Real-time binding experiments using surface plasmon resonance show

232 Real-time binding experiments using surface plasmon resonance spec

233 Binding experiments using the isolated GAF domain of EI(

234 Competitive binding experiments using unlabeled and 125I-M12A genera

235 rform in vitro catalytic activity assays and binding experiments using ZAP-70 proteins purified from

236 Binding experiments, using fluorescent liposomes, confir

237 In competition-binding experiments, V2 outcompetes SGS3 for substrate d

238 Direct binding experiments, via isothermal titration calorimetr

239 rs in the striatum as measured by D1- and D2-binding experiments was greatly diminished in the mutant

240 Through kinetic radioligand binding experiments, we characterized mutant receptors s

241 In combination with fluorescence binding experiments, we conclude that triclosan binds to

242 In further competition binding experiments, we identified 12 compounds with aff

243 s simulations, mutagenesis, and A1-GpIbalpha binding experiments, we identified a network of salt bri

244 ional analysis, and fluorescent polarization binding experiments, we identify here three structural m

245 Using scoC-lacZ fusions and DNA-binding experiments, we show here that scoC is directly

246 st two-hybrid assays followed by biochemical binding experiments, we show that the region in CAPS1 co

247 cations from dissociation of this dimer, DNA binding experiments were carried out using an SS crossli

248 Protein folding and TolA binding experiments were combined with real-time NMR spe

249 Binding experiments were conducted by fluorescence spect

250 Catch and release competitive binding experiments were done by NMR for the cation-carb

251 In vitro saturation binding experiments were performed for (99m)Tc-TCP-1 in

252 Cyanide-binding experiments were performed to assess trans effec

253 Surface plasmon resonance binding experiments were performed using immobilized gam

254 ac-2 in host-pathogen interactions, solution binding experiments were performed using surface plasmon

255 Enzyme-substrate and enzyme-inhibitor binding experiments were performed using water-ligand ob

256 (125)I-STa-binding experiments were performed with intestinal mucos

257 Meat binding experiments were performed with two technical TG

258 In addition, the SPR binding experiments were qualitatively simulated, confir

259 r recognition between VEGF and this aptamer, binding experiments were used to show that the HBD contr

260 s interaction are determined in a saturation binding experiment, where increasing concentrations of p

261 s is further supported by a series of direct binding experiments, which clearly demonstrate a high af

262 llosteric site were indicated by equilibrium binding experiments, which revealed different PLP-bindin

263 alysts has been quantified using a (31)P NMR binding experiment with triethylphosphine oxide (TEPO).

264 Binding experiments with [(3)H]N-methylscopolamine at th

265 Receptor binding experiments with [3H]MK-801 showed significant u

266 tein receptor (sLDLR) was employed in ligand binding experiments with a fluorescently tagged variant

267 on of vancomycin was achieved in competitive binding experiments with a horseradish peroxidase-vancom

268 To explain this phenomenon, we performed binding experiments with a peptide construct of the tail

269 e evaluated assay performance by competitive binding experiments with a series of known ligands and a

270 Binding experiments with alkyl-transfer-active and -inac

271 odeling and isothermal titration calorimetry binding experiments with an engineered PG9 mutant sugges

272 l into question many of the past kinetic and binding experiments with ATCase with nucleotides as the

273 Meat binding experiments with beef and pork were performed us

274 Competitive in vivo binding experiments with BR55 were performed in knock-ou

275 Binding experiments with circularly permutated DNA probe

276 Binding experiments with CTRC revealed that (i) inhibito

277 However, UV-vis, EPR, NIR MCD, and ligand binding experiments with ferrous and ferric Ns H-NOX ind

278 tical ultracentrifugation techniques and DNA binding experiments with fluorescently labeled DNA oligo

279 Equilibrium binding experiments with HeLa S(3) cells indicate that r

280 Binding experiments with heterologously expressed repeat

281 molecules allows one to perform competition binding experiments with high sensitivity while avoiding

282 Binding experiments with immobilized vitronectin suggest

283 Binding experiments with LA3-5 of LDLR and CR16-18 showe

284 application of this probe by performing NMR binding experiments with Lck and Src kinases and utilize

285 observed at those VIPs, even in competitive binding experiments with minute virus of mice using dual

286 2 N-terminal region were studied in in vitro binding experiments with purified gH/gL and in cell-cell

287 Comparative in vitro binding experiments with purified proteins demonstrated

288 In vitro binding experiments with purified virus polymerase and N

289 Binding experiments with radioactive (45)Ca(2+) demonstr

290 d and characterized by in vitro displacement binding experiments with rat brain membranes, in vitro a

291 Combined with binding experiments with site-directed ETS1 mutants, the

292 Turnover and equilibrium binding experiments with substrate analogs revealed that

293 The assay was tested in competitive binding experiments with substrates and products of KMO

294 Binding experiments with the complement components C3b a

295 spective Ki values determined in radioligand binding experiments with the purified receptor.

296 Binding experiments with the von Willebrand factor A3 do

297 SRA binding experiments with this domain gave negative resul

298 al to the mica substrate through qualitative binding experiments with Trichosanthes kirilowii aggluti

299 hMPV F compared to the other three mAbs, yet binding experiments with trimeric hMPV F showed limited

300 In binding experiments with wild-type (WT) sLDLR, FRET-depe