ライフサイエンスコーパス: binding site of

1 ue prediction were explored by surveying the binding sites of 1023 proteins.

2 and applied both to predict the genome-wide binding sites of 1312 TFs available from protein interac

3 the pT1471 phosphate occupies the phosphate-binding site of a canonical pY complex, while Y1473 occu

4 s, Ncd and KIFC3, to determine the potential binding site of a known KIFC1 ATPase inhibitor, AZ82.

5 nown function, one SNP is located in the DNA binding site of a member of the Plasmodium ApiAP2 transc

6 r non-cognate ligands to bind to the cognate binding site of a receptor.

7 ical probe to primarily occupy the co-factor binding site of a Su(var)3-9, enhancer of a zeste, trith

8 small-molecule "anchor" groups to a specific binding site of a target biopolymer.

9 ectroscopy (SRCS) process to determine which binding sites of a molecule preferentially bind to a pla

10 lish firm and specific interactions when the binding sites of a protein receptor have only low affini

11 approach was utilized to map the ssRNA/dsRNA binding sites of a purified recombinant protein and the

12 a glycoconjugate to simultaneously block all binding sites of a target lectin is key to robust inhibi

13 y that binds adjacent to the heparan sulfate binding site of A27, likely affecting ligand binding.

14 -helixes alpha3 and alpha4 represent the Vif-binding site of A3H.

15 In line with this finding, the binding sites of AATF within the 45S rRNA precursor loca

16 Disease-causing variations in the ATP-binding sites of ABCB4 cause defects in PC secretion, wh

17 ted patients who harbor mutations in the ATP-binding sites of ABCB4.

18 RAD51 Cys-319 resides within the SH3-binding site of ABL proto-oncogene 1, nonreceptor tyrosi

19 umanizing mutations in the vestibule-located binding site of AChBP to improve its suitability as a mo

20 The HBGA binding site of all known GII.14 strains remained conser

21 embrane proteins continue to reveal that the binding sites of allosteric modulators are widely distri

22 y for electrochemical detection of the metal-binding site of alpha-synuclein (alpha-syn).

23 primary binding site of alphaXbeta2 and the binding site of alphaMbeta2 on iC3b.

24 bly, there is no overlap between the primary binding site of alphaXbeta2 and the binding site of alph

25 ggests that vitamin K1 overlaps at the NADPH binding site of ALR2, which probably shows that vitamin

26 he N terminus of chECL1, suggesting that the binding site of ALV-J gp85 on chNHE1 is probably located

27 immunoprecipitation (iCLIP) to identify the binding sites of ALYREF, an mRNA export adaptor in TREX,

28 ues 22-31 that ultimately broadened the drug-binding site of AM2 S31N inhibitor 4, which spans residu

29 shown that AML1-ETO and RUNX1 co-occupy the binding sites of AML1-ETO-activated genes.

30 an unnatural amino acid fluorophore into the binding site of an EGFR-specific antibody fragment, resu

31 tivities can be developed from the chemokine-binding site of an evasin.

32 tors, to identify a component of the odorant-binding site of an OR from the malaria vector, Anopheles

33 genes, all of which contain conserved miR159-binding sites of analogous complementarity.

34 The binding sites of anions and aromatic rings in SIFSIX mat

35 e-specific conjugation away from the antigen-binding site of antibody fragments, with a controlled li

36 cells with plasmid carrying mutations in the binding sites of AP4 to Gal-1 promoter resulted in decre

37 nalysis, we identified several P. gingivalis-binding sites of ArcA, which led to the discovery of an

38 n binding site of lidocaine and the external binding site of aryl sulfonamides may have synergistic a

39 The Rab33B binding site of Atg16L1 comprises 20 residues and immedi

40 Our pCREs matched among others in vitro binding sites of B3, NAC, bZIP, and TCP TFs, which might

41 a challenge to identify the specific targets/binding sites of BACE1.

42 two serine residues in H5 at the orthosteric binding site of beta(1)AR, and find that formoterol has

43 as designed to target the Tcf4 G(13)ANDE(17) binding site of beta-catenin, extensive structure-activi

44 t the assignment of three Mg(2+) ions to the binding site of both hGGPPS and yGGPPS greatly improves

45 o 8.08+/-0.0610(4)L.mol(-1), at the warfarin binding site of BSA.

46 molecular modeling study demonstrated that A binding sites of BSA play the main role in the interacti

47 ogy model of AtABCC2 and probed the putative binding sites of C3G and GSH through site-directed mutag

48 tes of recombinant VP6 and the genomic dsRNA binding sites of capsid-associated VP6.

49 he binding interface between the tropomyosin-binding site of cardiac leiomodin and the N-terminus of

50 that favor competitive inhibition at the ATP binding site of CDK2 were identified and typically exhib

51 signals were differentially enriched in the binding sites of certain transcription factors, such as

52 nity labeling (PAL) was used to identify the binding site of chroman-4-one-based SIRT2-selective inhi

53 The binding site of class IIa deacetylases was previously ma

54 ate-dependent reduction of the dicarboxylate-binding site of complex II (site IIf); (b) pore opening

55 dependent manner and did not involve the PCh-binding site of CRP.

56 nd is only partially dependent on the glycan-binding site of CRT, which is generally relevant to subs

57 ions that are far from the regulatory Ca(2+)-binding site of cTnC.

58 two reducing-end mannoses into the domain A binding site of CV-N than with the nonreducing end unit.

59 the DNA-binding site and the histone/ATPase binding site of CW are located on the opposite sides of

60 -3 is found to disrupt the glycosaminoglycan-binding site of CXCL8 and inhibit the interaction of CXC

61 ggest that our compounds may target the Q(o) binding site of cytochrome bc(1).

62 The chromatin binding sites of DDX5 are G-rich sequences.

63 bearing implications for the so-far unknown binding site of delta on RNAP.

64 y or by competition interactions, either for binding sites of dissolved organic carbon or for biotic

65 nd supposed to interact with the orthosteric binding site of dopamine receptors, was actually a negat

66 The extracellular ligand-binding site of DRD2 is remodelled in response to agonis

67 eport a 2.1- angstrom structure and the drug-binding site of E's transmembrane domain (ETM), determin

68 f the takinib scaffold within the nucleotide-binding sites of each respective kinase.

69 nificantly enriched for transcription factor binding sites of EBF1, EP300, and CEBPB (P < 5e-6).

70 ment of both salt bridge partners in the ion-binding site of EcNhaA produced an electrogenic variant

71 In all cases, the m(6)A-binding site of ECT proteins is required for in vivo fun

72 reference compound (Erlotinib) into the ATP binding site of EGFR-TK domain (PDB ID:1M17) to elucidat

73 VPg directly bound the cap-binding site of eIF4E and competed for m(7)G cap analog

74 Taken together, our data indicate that the binding site of EphA2 on EBV gH/gL is at least in part p

75 The N-terminal Cdc13-binding site of Est1 cooperates with the TLC1-Ku-Sir4 pa

76 The DNA-binding sites of estrogen receptor alpha (ERalpha) show

77 and substrate binding pocket that mimick the binding sites of eukaryotic SLC6A18/B0AT3 and SLC6A19/B0

78 roximately 60 angstrom from the orthosomycin binding site of everninomicins.

79 ractions between C(2) H(2) molecules and the binding sites of FeNi-M'MOF.

80 onance (NMR)-based studies revealed that the binding site of FHL1 in CHIKV nsP3 HVD overlaps that of

81 ChIP-seq data demonstrate that binding sites of FLI1, a fate-determining factor promoti

82 terizes the recently disclosed three calcium binding sites of FXIII-A concerning evolution, mutual cr

83 Drugs targeting the orthosteric, primary binding site of G protein-coupled receptors are the most

84 Ric8A C-terminal tail helps organize the GTP-binding site of Galpha.

85 boxy terminus were identified as the primary binding site of Gbetagamma.

86 a vaccine that specifically target the HVEM binding site of gD.

87 ype-associated SNPs were present in microRNA-binding sites of genes involved in energy metabolism and

88 Asp(22) is part of the proton-binding site of GlcP(Se) and crucial for the glucose/H(+

89 red that mutations proximal to the substrate binding site of glycosyltransferase 8 domain containing

90 ed substantial diversity within the receptor binding site of H5N1 during human infection.

91 verlapping residues surrounding the receptor-binding site of haemagglutinin.

92 c diversity was detected within the receptor binding site of hemagglutinin of HPAI A/H5N1 viruses, ev

93 Three nitrated tyrosines reside in the heme-binding site of hemopexin, and we found that one, Tyr-19

94 covalently target a reactive cysteine in the binding site of Her2 and were further optimized by means

95 In this study, we have explored binding sites of host proteins, which are specific partn

96 llosteric paths between catalytic and ligand binding sites of hPDI.

97 the middle domain of Hsp90 and the J-protein binding site of Hsp70 in both E. coli and yeast.

98 our results suggest that these two essential binding sites of Hsp70s cooperate in protein folding.

99 The TPR binding site of Hsp90 cochaperones includes a shallow, p

100 The binding sites of hTMPK inhibitors were validated by phot

101 this article, we describe that the integrin-binding site of human CD40L is predicted to be located i

102 ation in the peptide YYCFQGNQFLR in the heme-binding site of human hemopexin, which was similarly nit

103 ith voltage-shifting mutations and the toxin-binding site of human Na(V)1.7, an attractive pain targe

104 Mutation of the amino acids S873 and T874 binding site of human TRPA1 significantly attenuated cha

105 Even though the binding sites of HuR and miR-330 do not overlap, the rec

106 The initial binding site of I2 in MFM-300(Sc), I2(I), is located nea

107 revealed NLS2 primarily binds the major-NLS binding site of importin alpha, unlike NLS1 that associa

108 ese MT-interacting elements overlap with the binding site of importins on TPX2.

109 sitive hits exclusively when a ligand at the binding site of interest is displaced; it mitigates fals

110 bias in ChIP-seq is challenging because the binding sites of interest tend to be more common in high

111 ingle amino acid difference near the solvent-binding site of iron, and X-ray crystallography revealed

112 to a monoglycopeptide shows that the GalNAc-binding site of its lectin domain is rotated relative to

113 portant for the stabilization (first calcium binding site) of its zymogenic form and the possible mod

114 use intact proteins to show that the lysine-binding site of K2(hPg) is a major determinant of the ac

115 The binding of PAM to the lysine-binding site of K2(hPg) relaxes the conformation of hPg,

116 mall-molecule inhibitor targeting the lysine-binding site of KIV-10 can combat the pathophysiological

117 Sequence analysis identified putative binding sites of known and novel transcription factors l

118 We demonstrate that fSHAPE patterns predict binding sites of known RBPs, such as iron response eleme

119 ons and to explore the relationship with the binding sites of known RBPs.

120 restingly, all proteins bound at the heparin-binding sites of laminin, including the globular domains

121 In the proposed model, the N-terminal actin-binding site of leiomodin can act as a "swinging gate" a

122 ations of agents targeted to the pore-region binding site of lidocaine and the external binding site

123 ynamic complex, we first mapped the adjacent binding sites of light chains MLC1 and ELC1 on the MyoA

124 ull-down (Chem-CLIP) to identify and map the binding sites of low molecular weight fragments that eng

125 The peptide primarily occludes the ACP binding site of LpxA.

126 The ligand-binding sites of many G protein-coupled receptors (GPCRs

127 technology such as ChIP-seq, the genome-wide binding sites of many proteins have been profiled under

128 Second, these motifs are enriched at the binding sites of methylation modifying enzymes including

129 ng the receptor inactive state, the putative binding site of Mg(2+) on the MOP receptor, as well as t

130 Specific binding sites of Mg(2+) in folded conformations of RNA h

131 e simulations shed light on 1) the preferred binding sites of Mg(2+) on the MOP receptor, 2) details

132 We have identified a highly conserved binding site of miR-124 in the 3'-untranslated region (3

133 Many of these SNPs are in binding sites of miRNAs and RNA-binding proteins, indica

134 and (S)-17b, which bind within the substrate-binding site of MMP-13 and surround the catalytically ac

135 site shows structural similarity to the GTP-binding site of MoaA, suggesting that the viperin substr

136 bout the underlying molecular mechanisms and binding sites of modulatory compounds, we know just the

137 ug-like compounds able to target the antigen-binding sites of most or all patients in a stereotyped s

138 druggable hot spots in the shallow inhibitor binding site of MraY that were not previously appreciate

139 disrupt communication between the nucleotide-binding site of myosin and its lever arm that drives for

140 nt with its repressive function, the genomic binding sites of Myt1l are similar in neurons and fibrob

141 substitutions that are found in the 2nd SIA-binding site of NA proteins of avian-derived IAVs that b

142 for designing proteins that recapitulate the binding sites of natural cytokines, but are otherwise un

143 in the rate of ligand binding to the primary binding site of neuraminidase due to the presence of gly

144 nt, but not of the precursor, bound the VEGF-binding site of neuropilin-1; the C-terminal arginine (R

145 that allosteric agents targeting the heparin-binding site of neutrophil elastase would offer a therap

146 The binding site of NF023, identified by NMR spectroscopy an

147 The allosteric binding site of NMS overlaps with the binding site of so

148 both VEGFR2 and NRP1, including the VEGF164-binding site of NRP1 and the NRP1 cytoplasmic domain (NC

149 ctivity when targeting the peptide substrate binding site of NTMT1/2.

150 logue to occupy both substrate- and cofactor-binding sites of NTMT1, but the bisubstrate analogue wit

151 ealed that 4 occupies substrate and cofactor binding sites of NTMT1.

152 ed CpGs downstream from SALL4 TSS are within binding sites of octamer-binding transcription factor 4

153 Transcription start sites are also binding sites of Origin Recognition Complex 1 (ORC1).

154 agent should be important for locating metal-binding sites of other metalloproteins.

155 f several cis-regulatory motifs representing binding sites of other TFs, such as ABFs, ERF1, MYB1, LT

156 We identified a major DNA-binding site of PALB2, mutations in which reduce RAD51 f

157 tide sequence (I56-K68) overlapping with the binding sites of patients' serum IgEs.

158 osteroid pregnenolone sulfate (PES), but the binding site of PES on the NMDAR and the molecular mecha

159 he single canonical conserved 3' UTR miR-290-binding site of Pfn2 or overexpression of the Pfn2 open

160 Here we present the mutations in the ATP-binding site of PI3Kalpha to progressively transform the

161 kets within the adenosine triphosphate (ATP) binding site of PI3Kgamma.

162 s feature different regulatory programs: the binding sites of pioneer TFs of FOX family are specifica

163 ressing a FRET-biosensor comprising the cGMP-binding sites of PKGIalpha.

164 nalogues blocking both, primed and nonprimed binding sites of plasmin.

165 Mutations of the arsenic-binding site of PML/RARA, but also PML, have been detect

166 high-quality motifs that represent putative binding sites of primary factors and cofactors.

167 ions in the canonical actin- or poly-proline-binding sites of profilin.

168 Furthermore, the structure revealed (i) the binding site of proMPO-processing proconvertase, (ii) th

169 that stolonidiol binds to the phorbol ester binding site of protein kinase C (PKC), induces transloc

170 ional suppressor mutations in the acetyl-CoA binding site of pyruvate carboxylase (PycA) rescued cefu

171 lection of a nucleotide change at the miR172 binding site of Q contributed to subcompact spikes and f

172 ndings support a model in which the relative binding sites of Rad54 and Rdh54 help to define their fu

173 s bound with high affinity with the effector-binding site of Ras in an active conformation.

174 Although in vivo binding sites of RBPs can now be determined genome-wide,

175 od is less capable of identifying the longer binding sites of RBPs.

176 the location of the transition state and the binding site of reaction intermediates are often decoupl

177 otein fingerprinting assay, to map the ssRNA binding sites of recombinant VP6 and the genomic dsRNA b

178 In the two cAMP-binding sites of RIalpha, exocyclic phosphate oxygens of

179 r EDC/GEE, are used together to pinpoint the binding sites of rifamycin SV, doxycycline, and another

180 ions between m5C and micro RNA target sites, binding sites of RNA binding proteins, and N6-methyladen

181 sion and splicing QTLs and are enriched with binding sites of RNA-binding proteins, RNA structure-cha

182 dence that SA acts at or near the ubiquinone binding site of SDH to stimulate activity and contribute

183 Individual binding sites of select KSHV gene products on PAN RNA we

184 its analogues bind to the central substrate-binding site of SERT, stabilize the outward-open conform

185 faces the outside of the protein and is the binding site of several animal toxins, and the palm, a c

186 n (F1) contains a previously undetected Rap1-binding site of similar affinity to that in F0.

187 ific hypomethylated regions are enriched for binding sites of similar transcription factors, suggesti

188 steric binding site of NMS overlaps with the binding site of some allosteric, ectopic and bitopic lig

189 ind significant enrichment for the consensus binding sites of Sox2, Six1 and Gata3-transcription fact

190 We show that the binding site of SrmB is unperturbed by SrmB deletion, bu

191 an SULT allosteric binding site-the catechin-binding site of SULT1A1 bound to epigallocatechin gallat

192 tructure of an NSAID allosteric site-the MEF-binding site of SULT1A1-is determined using spin-label t

193 Here, the catechin-binding site of SULT1A3, which sulfonates monoamine neur

194 The glycan-binding site of T1 sigma1 is located in the head domain

195 In contrast to T1 sigma1, the carbohydrate-binding site of T3 sigma1 is located in the tail domain,

196 expression and genetic variation in microRNA-binding sites of target genes on growth and muscle quali

197 region homologous to the muscarinic receptor-binding site of Tau suggests that MAP2c also may regulat

198 Our findings disclose the binding site of TbFPC4 on TbBILBO1-NTD, which may provid

199 ther cell types could be used to predict the binding sites of TFs of interest.

200 The overall architecture and NADP(+)-binding site of Tfu-FNO were highly similar to those of

201 and HS is strong, the conformational heparin binding site of TG2 is not conserved, suggesting that TG

202 ctures that otherwise sequester the ribosome-binding site of the 3'gene.

203 unnel of RNAP aligns with the Shine-Dalgarno-binding site of the 30S subunit.

204 sential intersubunit bridge, and a secondary binding site of the AGs.

205 en-bonding and hydrophobic groups at the ice-binding site of the antifreeze protein TmAFP of Tenebrio

206 r KCa3.1 over KCa2.3, we first localized the binding site of the benzothiazoles/oxazoles to the CaM-B

207 ogical approaches, we have characterized the binding site of the cellular FHL1 protein in CHIKV HVD a

208 -alpha3 loop directly interacts with the ATP-binding site of the CKI1 histidine kinase domain.

209 inhibitor that binds selectively to the ATP-binding site of the D2 domain, although both the D1 and

210 To test this hypothesis, we blocked the CD4 binding site of the envelope antigen and compared it to

211 und 2 (Ki = 19 nM) binds within the aldehyde-binding site of the free enzyme species of ALDH2.

212 gabazine for binding to (i) the orthosteric binding site of the GABA(A) receptor and (ii) the high-a

213 It is known that the Na(+) binding site of the GIRK1 subunit is defective, but the

214 dicts that indole docks perfectly to the ATP binding site of the GyrB subunit.

215 mutations in close proximity to the receptor-binding site of the HA molecule determined the antigenic

216 the positions were located near the receptor binding site of the HA protein, as they are in the HA pr

217 Our study identifies the binding site of the highly toxic convulsant tetramethyle

218 es, which recognize the conserved coreceptor-binding site of the HIV-1 envelope glycoprotein (Env), c

219 neered variant of VRC01 that targets the CD4 binding site of the HIV-1 envelope protein.

220 169R mutation located at the second receptor binding site of the HN protein contributed to a complex

221 anges in regions surrounding the orthosteric binding site of the human 5-HT(3A) (h5-HT(3A)) receptor

222 itch 1 away from the G-domain and nucleotide-binding site of the KRAS protein.

223 tides to Ral proteins was quantified and the binding site of the lead peptide on RalB was determined

224 tor and, conversely, binding to the receptor-binding site of the ligand.

225 ccupancy of GATA-1, OGT, and OGA at the GATA-binding site of the lysosomal protein transmembrane 5 (L

226 We have now determined the cholesterol-binding site of the M2 protein in phospholipid bilayers

227 ers for the in vivo imaging of an allosteric binding site of the M4 receptor.

228 ma1, and sigma2 receptors as well as the PCP binding site of the NMDA receptor.

229 himeras and point mutants we have mapped the binding site of the P2X7R-selective antagonist AZ1164537

230 ant in which aspartate residues in the metal-binding site of the polymerase domain were replaced by a

231 Tumors with mutations in the SMAP-binding site of the PP2A A subunit displayed resistance

232 g indicated that all the residues of the ATP-binding site of the prototypical kinase PKA, except the

233 he two most common are binding to the ligand-binding site of the receptor and, conversely, binding to

234 by ligands interacting with the orthosteric binding site of the receptor to incorporate concepts of

235 y and binding predominantly to the adenosine binding site of the tankyrase catalytic domain.

236 site of a gene is regulated by a particular binding site of the TF.

237 type 1 (HIGM1) are clustered in the integrin-binding site of the trimeric interface.

238 with specific point mutations in the miR-33 binding sites of the Abca1 3'untranslated region, which

239 (a) and an antibody targeting ligand-induced binding sites of the activated GPIIb/IIIa receptor (MBDu

240 tions, i.e., positions were located near the binding sites of the allosteric ligand being assessed.

241 epitope and membrane via two specific lipid binding sites of the antibody paratope.

242 Mutations in putative membrane-binding sites of the C(2)C domain disrupt the ability of

243 ed recombinant protein and the genomic dsRNA binding sites of the capsid-associated VP6.

244 and deactivates both of the divalent cation-binding sites of the cTnC C-domain.

245 We show that budding yeast Ty3/Gypsy co-opts binding sites of the essential meiotic transcription fac

246 cers active in liver cells, enriched for the binding sites of the FOXA1, FOXA2 and HNF4A transcriptio

247 study demonstrate that the deletions of the binding sites of the G3BP and FXR protein families in th

248 graft survival, estimated AA MMs at peptide-binding sites of the HLA-DRB1 molecule account for an im

249 We used Targeted DamID to identify genomic binding sites of the Hunchback temporal factor in two ne

250 the cases, the hotspots overlapped with the binding sites of the interacting proteins.

251 oth BRM and H2A.Z, both factors overlap with binding sites of the light-regulated transcription facto

252 ivate both the glutamate and glycine agonist-binding sites of the N-methyl-d-aspartic acid receptor.

253 at interact in a one-to-one fashion with the binding sites of the other polymer.

254 r being an integer multiple of the number of binding sites of the other.

255 in an effort to better understand the metal binding sites of the partially metalated forms of human

256 er partially occupies the ATP- and substrate-binding sites of the partner monomer.

257 q, together with NMR analysis of the H3K4me3-binding sites of the PHD fingers from PHF23, KDM5A and B

258 veral Ile methyl groups located in different binding sites of the protein were assigned and used to c

259 s the binding of agonists to the orthosteric binding sites of the receptor.

260 engagement of the allosteric and orthosteric binding sites of the receptor.

261 nine nucleotides to the canonical nucleotide binding sites of the regulatory Bateman domain induces d

262 llicKZ, this protein associates with two RNA binding sites of the RNase E component of the Pseudomona

263 CRS regions (1) colocalize consistently with binding sites of the same RNA binding proteins (RBPs) or

264 nd hydrophobic grooves resembling preprotein-binding sites of the SecB chaperone.

265 ns of the FGF12-FGFR1c2 and FGF22-FGFR1c2 HS binding sites of the symmetric FGF2-FGFR2-HS2 signal tra

266 We noted that the ATP/inhibitor-binding sites of the TAM members closely resemble each o

267 ically, NR4A1 is preferentially recruited to binding sites of the transcription factor AP-1, where it

268 ions of active promoters, CpG island shores, binding sites of the transcription factor CTCF and brain

269 corresponded to the catalytic and substrate binding sites of the two enzymes.

270 X-MS) was used to map the membrane and NDP52 binding sites of the ULK1 complex to unique regions of t

271 r dynamics simulation studies elucidated the binding site of these aniline-based influenza fusion inh

272 understand the role of individual metal-ion binding sites of these domains in the membrane associati

273 In addition, we map the binding sites of these proteins using a combination of P

274 l analyses using agonists to map the odorant-binding sites of these receptors have been limited becau

275 ches to comprehensively map the identity and binding sites of these RNAs are lacking.

276 GMPK CORE domain distant from the nucleotide-binding site of this domain modulate enzymatic activity

277 ermines the properties of the benzodiazepine binding site of those receptors.

278 These results identify the NAD(+)-binding site of TNT.

279 clude is Avo3, occludes the FKBP12-rapamycin-binding site of Tor2's FRB domain rendering TORC2 rapamy

280 t a position distinct from the extracellular binding site of TPO, bypasses this inhibition, providing

281 We compared binding sites of TRAMP components with multiple nuclear

282 ification marks, chromatin accessibility and binding sites of transcription factors and co-activators

283 th the location of enhancers in CECs and the binding sites of transcription factors in the AP-1/ATF f

284 MECOM, SMAD4, and SNAI3) and depleted of the binding sites of transcriptional activators.

285 Also, these regions are enriched for the binding sites of transcriptional repressors (such as CTC

286 ability analysis, we evaluated the potential binding sites of TTP to 3'-untranslated regions (3'-UTR)

287 These findings suggest that the Abeta-binding site of TTR may be hidden in its tetrameric form

288 f CCB02, which selectively binds at the CPAP binding site of tubulin.

289 cell-cycle-regulatory miRNAs and the 3' UTR binding site of tumor suppressor miRNAs.

290 A compact bPNA+binding site of two U6 domains can be genetically encode

291 er rearranges to bridge the C-terminal pS729 binding sites of two BRAFs, which drives the formation o

292 toichiometry of K2hPg/VKK38, with the lysine-binding sites of two K2hPg domains anchored to two regio

293 nts by phage display that bind the back side binding site of Ubc9 and function as SUMO-based Ubc9 inh

294 We determined the binding sites of unphosphorylated and phosphorylated MAP

295 The binding sites of volatile anesthetics isoflurane and sev

296 is of great significance to study the metal-binding site of wild-type alpha-syn (48-53, VVHGVA) and

297 nd XPD while capping the DNA-binding and ATP-binding sites of XPD.

298 ds to the identification of a potential drug-binding site of ZIKV NS5, which might facilitate the dev

299 stidine-rich motifs, which are the predicted binding site of Zn(2+) in the Zn-deficiency response.

300 he efficiency of the method by mapping metal-binding sites of Zn(7-x)MT species using a bottom-up MS