ライフサイエンスコーパス: binuclear

1 being bridged by AsO4 bound in a monodentate binuclear (2)C complex (chain model).

2 As adsorption occurs primarily as bidentate binuclear ((2)C) inner-sphere surface complexes.

3 incubation with a synthetic precursor of the binuclear [2Fe] subcluster, namely: [NEt4]2[Fe2(adt)(CO)

4 We further demonstrate that binuclear acinar cells are terminally differentiated aci

5 us of Ag is evident in the EPR signal of the binuclear active site observed upon reduction with CO, i

6 o what is known about the bioassembly of the binuclear active site of [NiFe] hydrogenase and the nitr

7 n spectroscopy and extended it to the entire binuclear active site of an oxygen-tolerant [NiFe] hydro

8 the progenitor RAPTA-C anticancer drugs, the binuclear agents neither arrest specific cell cycle phas

9 notion for a radical mechanism as well as a binuclear alpha-hydrogen abstraction pathway being opera

10 2 Nb}2 (mu2 -CH)(mu2 -H)(mu2 -Cl)] (3) via a binuclear alpha-hydrogen elimination.

11 activator CuIBr/TPEN existed in solution as binuclear and mononuclear complexes in equilibrium but a

12 Fusion of nuclei in binuclear and polynuclear microspores occurs spontaneous

13 rates triads, dyads, and monads that contain binuclear and polynuclear microspores.

14 One binuclear and six tetranuclear clusters are arranged, ma

15 Moreover, approximately 42% of binuclear and tetraploid cells assemble aberrant spindle

16 on-sulfur clusters, four to five (one or two binuclear and three tetranuclear) could be detected by E

17 involving monodentate-mononuclear/bidentate-binuclear As-Fe complex formation via legend exchange.

18 ycle involving initial oxidation of Au(I) to binuclear Au(II)-Au(II) complexes by Selectfluor, follow

19 We propose binuclear Au(II)-Au(II) complexes to be key intermediate

20 We report that binuclear benzo[h]quinoline-ligated Ni(II) complexes, up

21 al adsorption complexes, namely inner-sphere binuclear bidentate.

22 group 4 "constrained geometry" catalysts and binuclear bisborane and bisborate cocatalysts have been

23 and arsenite exclusively formed monodentate-binuclear ("bridging") complexes (R(As-Fe) = 3.31-3.34 A

24 ecipitated hydrous ferric oxide (HFO) in the binuclear, bridging ((2)C) complex.

25 g DFT computational analyses, and involves a binuclear C-H bond-activation process.

26 repositories, where the predominance of the binuclear Ca(2+) complex, which is a precursor of variou

27 While the structural similarity of the binuclear calcium-binding sites in anthrax protective an

28 intense proliferative burst of predominantly binuclear cardiomyocytes.

29 mer structures can be obtained by using such binuclear catalyst/cocatalyst systems.

30 Furthermore, the binuclear catalysts exhibit enhanced AO tolerance and en

31 t herein a study of the reaction pathway for binuclear CcrA from Bacteroides fragilis using density f

32 Binuclear cell nuclei combine their genomes on a single

33 esis of mononuclear cells contributes to the binuclear cell pool, whereas enclosure of entire mitotic

34 ophans are localized relatively far from the binuclear center (30-60 A); therefore, oxidation probabl

35 both the pump loading site (PLS) and to the binuclear center (BNC) are thermodynamically driven by e

36 coupled to the reduction of the active site binuclear center (BNC).

37 e high-pH side of the membrane each time the binuclear center active site is reduced.

38 During turnover, the binuclear center apparently shuttles via a metastable bu

39 bed by the reduction of the heme d/heme b595 binuclear center at the active site.

40 electron reduction of dioxygen to water in a binuclear center comprised of a high-spin heme (heme a(3

41 ake and maintenance of net charge within the binuclear center domain.

42 or input pathway for protons which go to the binuclear center for water formation ("chemical protons"

43 In contrast, reduction of the binuclear center in the "as-isolated" ferric/cupric enzy

44 ibonucleotide reductase to match that of the binuclear center in the hydroxylase component of methane

45 ox-linked export of a pumped proton from the binuclear center into the exit pathway.

46 ince both modifications are prevented if the binuclear center is first blocked with cyanide.

47 rosine hydroxyl group is protonated when the binuclear center is oxidized but deprotonated in the P(M

48 f the dominant EPR spectrum from the coupled binuclear center of Mn/Mn-PTE requires slightly rhombic

49 rogen peroxide does more than react with the binuclear center of oxidized bovine cytochrome c oxidase

50 tryptophan and cardiolipin proceeds via the binuclear center since both modifications are prevented

51 the proton may instead be transferred to the binuclear center to complete the oxygen reduction chemis

52 migration of a free radical generated at the binuclear center to these distal reaction sites.

53 g while continuing to channel protons to the binuclear center without inhibiting the oxidase activity

54 s initial binding of H2 to the copper of the binuclear center, displacing the bound water, followed b

55 into the binding pocket of the loosely bound binuclear center, originally occupied by the nucleophili

56 One proton goes to the binuclear center, whereas the other is pumped to the low

57 6 residue physically impede NO access to the binuclear center.

58 a copper-hydride intermediate to reduce the binuclear center.

59 al change takes place in the vicinity of the binuclear center.

60 ggest regulation of the oxygen supply to the binuclear center.

61 and leads to another acidic residue near the binuclear center.

62 m E286 to the heme a(3) D-propionate and the binuclear center.

63 f CcO are unrelated to ligand binding to the binuclear center.

64 reaction likely proceeds via an unsymmetric binuclear chromium bis(mu-oxo) complex.

65 novel protein with the Gal4-type Zn(II)2Cys6 binuclear cluster DNA-binding motif at the N terminus.

66 Hap1 belongs to the Zn(2)Cys(6) zinc binuclear cluster family of transcription factors that t

67 The binuclear cluster N1a and the tetranuclear cluster N7 ar

68 The zinc binuclear cluster transcription factor CLR-1 is necessar

69 llection identified two uncharacterized zinc binuclear cluster transcription factors (clr-1 and clr-2

70 ctors, including the fungal Zn(II)2Cys6 zinc binuclear cluster transcription factors, the DNA binding

71 (CO)(2)(CN)] organometallic precursor to the binuclear cluster.

72 g that the two Mn(II) ions are not forming a binuclear cluster.

73 inal coiled-coil and a carboxy-terminal zinc binuclear cluster.

74 The binuclear Co-complexes are coordinated to mu-bonded, fiv

75 opropylphenyl) (3a) in THF cleanly forms the binuclear cobalt nitride Na(THF)(4){[((ket)guan)Co(N(3))

76 It has been established that this binuclear cofactor is synthesized and assembled by three

77 yzed by Pd(2)(dba)(3) and CyPF-(t)Bu was the binuclear complex [Pd(CyPF-(t)Bu)](2)(mu(2),eta(2)-dba)

78 first Cu(II) and that His175 stabilizes the binuclear complex by rearrangement of the CcP heme-coord

79 A butterfly-like phosphorescent platinum(II) binuclear complex can undergo a molecular structure chan

80 for the functioning of both Co2+ ions of the binuclear complex found in the X-ray structure of E. col

81 ononuclear complexes in equilibrium but as a binuclear complex in its single crystals.

82 y published MntR.Mn(2+) structure revealed a binuclear complex of manganese ions with a metal-metal s

83 Cu(II/I) by formation of a hydroxide-bridged binuclear complex, Mn(II)(mu-OH)Mn(II), at the substrate

84 trongly activating because they can form the binuclear complex, while smaller metal ions cannot bind

85 (pop-BF2)(6-) a very rare 6p(2) sigma-bonded binuclear complex.

86 tivity difference between the trinuclear and binuclear complexes at parity of histamine ligand is str

87 The synthesis of a series of binuclear complexes comprising bis(2,2':6',2' '-terpyrid

88 monodentate surface complexes to bidentate, binuclear complexes had Gibbs free energies of activatio

89 m and calcium complexes of MntR also contain binuclear complexes with a 4.4 A internuclear separation

90 Previous work has shown that MntR forms binuclear complexes with Mn(2+) or Cd(2+) at two binding

91 Novel binuclear complexes, 4,4'-bis{[N-(2,6-diisopropylphenyl)

92 the zero-field splitting parameter D in two binuclear complexes, [Cu(CF(3)COO)(2) x CH(3)CN](2) and

93 escent molecular rotor, only observed in the binuclear compound, was decreased with increasing viscos

94 lent mu-eta(2):eta(2) peroxy bridged coupled binuclear copper active sites.

95 xidation of phenols to catechols through the binuclear copper centres.

96 rsion of carbon dioxide into oxalate using a binuclear copper complex and a mild reducing agent.

97 ted that this enzyme belonged to the coupled binuclear copper enzyme (CBC) family.

98 The binuclear copper enzyme tyrosinase activates O2 to form

99 In tyrosinase, a binuclear copper enzyme, a mu-eta(2):eta(2)-peroxodicopp

100 of aromatic substrates catalyzed by coupled binuclear copper enzymes has been observed with side-on-

101 Tyrosinases are ubiquitous binuclear copper enzymes that oxygenate to Cu(II) 2 O2 c

102 rises from TCNQ guest molecules bridging the binuclear copper paddlewheels in the framework, leading

103 sites in the oxidized form of the noncoupled binuclear copper protein peptidylglycine alpha-hydroxyla

104 erimentally derived mechanism of the coupled binuclear copper protein tyrosinase.

105 ional and spectroscopic model of the coupled binuclear copper protein tyrosinase.

106 Cu(A) is a binuclear copper site acting as electron entry port in t

107 Recent studies support a binuclear copper site as the catalytic center.

108 A homologous series of binuclear copper(II) complexes [Cu(II)(2)(Nn)(Y)(2)](2+)

109 opy (EXAFS), the formation of both bidentate binuclear corner-sharing ((2)C) and bidentate mononuclea

110 rdination at a distance of 3.43 A suggests a binuclear corner-sharing adsorption/incorporation U(IV)

111 suggested predominant formation of bidentate binuclear corner-sharing complexes ((2)C) for As(V), and

112 This anion was attracted via bidentate binuclear corner-sharing coordination between SeO3(2-) t

113 ixture of As(III) and As(V), forms primarily binuclear, corner-sharing As(V) surface complexes on EC

114 nds 4 mol equiv of Cu (I) to form an alpha3N binuclear Cu (I) 2S 4 cluster by X-ray absorption spectr

115 monooxygenase (PHM), which has a noncoupled binuclear Cu active site.

116 d exchange coupling interactions between the binuclear Cu centers.

117 O(2) intermediates in the coupled binuclear Cu enzymes can be trapped and studied spectros

118 Possible intermediates in noncoupled binuclear Cu proteins can be defined through correlation

119 ferent intermediates in these two classes of binuclear Cu proteins exhibit different reactivities tha

120 Coupled binuclear Cu proteins include hemocyanin, tyrosinase, an

121 Noncoupled binuclear Cu proteins include peptidylglycine alpha-hydr

122 Binuclear Cu proteins play vital roles in O(2) binding a

123 Cu(I) and TEMPO-H are oxidized by O(2) via a binuclear Cu(2)O(2) intermediate and (2) "substrate oxid

124 ntain antiferromagnetically exchange-coupled binuclear Cu(2+) sites in which two Cu(2+) ions are brid

125 A primary example is the binuclear Cu(A) center, an electron transfer cupredoxin

126 This binuclear Cu(I) site reacts with N2O to generate the exp

127 ](2+) active sites from the reaction between binuclear Cu(I) sites and N2O in the 10-membered rings C

128 rdinate was evaluated for two representative binuclear Cu(I) sites.

129 n contrast to the nucleophilic reactivity of binuclear Cu(II) end-on peroxo species.

130 structures confirm the complexes to contain binuclear Cu(II) paddlewheel nodes each bridged by four

131 oroform gives a mixture of two regioisomeric binuclear diaminocarbene complexes.

132 or Si, on the other hand, are found to form binuclear dihydride complexes of the type Me(2)E(R(n)C(5

133 s unique tetranuclear active site Cu(Z), the binuclear electron entry point Cu(A) is also utilized in

134 of classical ligand-bridged intermediates in binuclear eliminations) in halogen elimination reactions

135 CcrA is the prototypical binuclear enzyme belonging to the B1 MbetaL family, whic

136 a trinuclear Fe binding center comprising a binuclear Fe binding center (sites A and B), homologous

137 terized high-valent mono- and di-oxo bridged binuclear Fe model complexes.

138 -peroxo 3 are compared with those of related binuclear Fe- and Cu-peroxo compounds.

139 ith aryldiazoacetates was achieved using the binuclear gold catalyst (S)-xylylBINAP(AuCl)(2), activat

140 zoacetates with enol ethers catalyzed by the binuclear gold complex (R)-DTBMSegphos(AuCl)2 activated

141 The reaction employs a binuclear gold(I) bromide as a catalyst and Selectfluor

142 In part, this reaction is mediated by the binuclear heme a3/CuB active site of cytochrome c oxidas

143 n of the ferric/cupric state of the enzyme's binuclear heme a3/CuB center is coupled to proton pumpin

144 spin heme b(558) that donates electrons to a binuclear heme b(595)/heme d center.

145 ide on the redox properties of an engineered binuclear heme-copper center in myoglobin (Cu(B)Mb) were

146 5)H(3)N, reacts with excess H(2) to give the binuclear hydride species, {[N(3)]Ru(H)}(2)(mu-eta(1):et

147 d EXAFS results indicated that the bidentate binuclear inner sphere was the most probable type of lig

148 iple layer SCM by implementing the bidentate-binuclear inner-sphere complexation identified in the pr

149 ms both outer-sphere complexes and bidentate-binuclear inner-sphere complexes on ferrihydrite surface

150 e NMR results suggest formation of bidentate binuclear inner-sphere surface complexes was the dominan

151 Reductive elimination via ligand-bridged binuclear intermediates from bimetallic cores is one mec

152 oli ribonucleotide reductase (R2) contains a binuclear iron cluster with inequivalent binding sites:

153 ld be a structural mechanism used by natural binuclear iron enzymes to drive their reactions past per

154 the four conserved His-Glu motifs suggest a binuclear iron mediated reaction mechanism, distinct fro

155 in which monomers A and B exhibit mono- and binuclear iron occupancy, respectively.

156 e to glutamate substitution (R2-D84E) at the binuclear iron site modifies the endogenous ligand set o

157 e of [FeFe] hydrogenase contains a catalytic binuclear iron subsite coordinated by CN(-) and CO ligan

158 n proposed that the electron transfer to the binuclear iron-copper center of O2 reduction initiates t

159 c cubane [4Fe-4S]-cluster (4FeH) linked to a binuclear iron-sulfur cluster (2FeH) that has an open co

160 Hydrolysis of a Pacman-shaped binuclear magnesium complex of a polypyrrolic Schiff bas

161 complex yields an unprecedented view of the binuclear manganese cluster and illuminates the structur

162 The binuclear manganese metalloenzyme human arginase I (HAI)

163 Arginase is a binuclear manganese metalloenzyme that catalyzes the hyd

164 Arginase is a binuclear manganese metalloenzyme that serves as a thera

165 ral comparisons of arginase with the related binuclear manganese metalloenzymes agmatinase and procla

166 A binuclear manganese molecular complex [(OH2)(terpy)Mn(mu

167 to propose a chemical mechanism for mono and binuclear MbetaLs.

168 ing NMR, EPR, and mass analyses, indicates a binuclear mechanism involving an O-atom transfer by a pe

169 chiseptica (BbZIP) revealed an unprecedented binuclear metal center (BMC) within the transport pathwa

170 at the binding of substrate analogues to the binuclear metal center diminishes the population of hydr

171 ly of hydrolytic enzymes is a mononuclear or binuclear metal center embedded within the confines of a

172 ile is mirrored by structural motions of the binuclear metal center in the active site.

173 n folds as a (beta/alpha)7beta-barrel, and a binuclear metal center is found at the C-terminal end of

174 X-ray diffraction studies have shown that a binuclear metal center is positioned in the active site

175 onstrated that the active site consists of a binuclear metal center positioned at the C-terminal end

176 The active site is composed of a binuclear metal center similar to that found in phosphot

177 structure the phosphonate moiety bridges the binuclear metal center, and one oxygen atom interacts wi

178 that bridges the two divalent cations of the binuclear metal center.

179 rotonation of the hydroxide that bridges the binuclear metal center.

180 d through complexation with a mononuclear or binuclear metal center.

181 ia complexation to the beta-metal ion of the binuclear metal center.

182 ion that occupied the alpha site within the binuclear metal center.

183 zinc translocation pathway consisting of two binuclear metal centers and an interim zinc-binding site

184 In the binuclear metal centers, the carbonyl and phosphoryl gro

185 ld, with four acidic residues coordinating a binuclear metal cluster within the active site, whose to

186 h mononuclear [MOH](+) and double protonated binuclear metal clusters [M(mu-OH)(2)M](2+) (M = Mg, Ca,

187 A binuclear metal coordination complex of the first thiazy

188 Various binuclear metal ion clusters and complexes have been rec

189 The protein consists of a core binuclear metallo-phosphoesterase fold (exemplified by b

190 first and second coordination spheres of the binuclear metallocofactor can be combined in an additive

191 sterase (PTE) from Pseudomonas diminuta is a binuclear metalloenzyme that catalyzes the hydrolysis of

192 Phosphotriesterase (PTE) is a binuclear metalloenzyme that catalyzes the hydrolysis of

193 Simulating such binuclear metalloenzymes accurately but computationally

194 a for other phosphodiesterase members of the binuclear metallophosphoesterase family and draw inferen

195 Seven signature amino acids of the binuclear metallophosphoesterase superfamily serve as th

196 rial and archaeal MPE proteins belong to the binuclear metallophosphoesterase superfamily that includ

197 a novel clade of DNA endonuclease within the binuclear metallophosphoesterase superfamily.

198 Binuclear metallophosphoesterases are an enzyme superfam

199 stal structure and bound by coordinating the binuclear metals and forming hydrogen bonds and nonpolar

200 synthesized and characterized a panel of new binuclear mixed valence Cu(I,II) complexes containing su

201 toxic in vivo single-dose evaluation for two binuclear mixed-valence Cu(+1)/Cu(+2) redox-active coord

202 1 sites is well defined, yet its role in the binuclear mixed-valent CuA sites is less clear.

203 reactive RNA ends are in the vicinity of the binuclear Mn(2+) active center, which provides detailed

204 cture and harboring the active site with the binuclear Mn(2+) ions.

205 i) mechanism for its transformation into the binuclear Mn(II) complex with ((H)O)L-L(OH) and its hydr

206 d the synthesis of a functionally equivalent binuclear Mn(II) species.

207 resents the first characterized example of a binuclear Mn(III)-peroxo, and a rare case in which more

208 on [Mn(II)] concentration, consistent with a binuclear Mn(O2(2-)) Mn peroxo.

209 Vibrational and metrical parameters for binuclear Mn-peroxo 3 are compared with those of related

210 ediate state trapped during reduction of the binuclear Mo/Cu enzyme CO dehydrogenase by CO.

211 active site of the native enzyme is a unique binuclear molybdenum- and copper-containing center.

212 zation of intermediates formed en route to a binuclear mono-oxo-bridged Mn(III) product {[Mn(III)(S(M

213 The synthesis of discrete, cationic binuclear mu-aryl dicopper complexes [Cu2(mu-eta(1):eta(

214 n one intermediate is observed en route to a binuclear mu-oxo-bridged product derived from O2.

215 The reactivity of these binuclear Ni complexes highlights the fundamental differ

216 The binuclear Ni(III) -Ni(III) intermediate lacks a Ni-Ni bo

217 ubunit of the ACDS complex and composed of a binuclear Ni-Ni site bridged by a cysteine thiolate to a

218 mposed of an [Fe(4)S(4)] center bridged to a binuclear Ni-Ni site.

219 A series of binuclear NiNi complexes supported by a single thiolate

220 This binuclear [(NO)Fe(N2S2)Fe(NO)2](+) complex maintains str

221 otein fold and primary ligand set of various binuclear non-heme iron enzymes.

222 ctivating step of the catalytic cycle of the binuclear nonheme iron enzyme Delta(9) desaturase.

223 High-valent intermediates of binuclear nonheme iron enzymes are structurally unknown

224 on the high-valent oxo intermediates in the binuclear nonheme iron enzymes.

225 Binuclear organometallic molecules are model systems for

226 Shown herein is that mono- and binuclear organoscandium complexes with a borate cocatal

227 ribution describes the implementation of the binuclear organotitanium "constrained geometry catalysts

228 ed by radicals and proceeds by an unexpected binuclear outer-sphere mechanism to cleanly form trans-i

229 bio-inspired electrochemical sensor using a binuclear oxo-manganese complex was evaluated and applie

230 ion the reducing equivalent is stored on the binuclear part, ([4Fe-4S](2+)Fe(II)Fe(I) --> [4Fe-4S](2+

231 escence intensity of the nano optical sensor binuclear Pd(atz,ur) complex at 457nm by the 2-chloro-4-

232 computational studies of the oxidation of a binuclear Pd(II) complex with "CF(3)(+)" reagents.

233 In contrast, oxidation of binuclear Pd(II) complexes with electrophilic trifluorom

234 Oxidation of binuclear Pd(II) complexes with PhICl(2) or PhI(OAc)(2)

235 nt, and formally electron-deficient (32e(-)) binuclear Pd(II)-C(0) complexes of 2-methyl-1H-indene we

236 The observation that binuclear Pd(III) and mononuclear Pd(IV) complexes are a

237 (OAc)(2) has previously been shown to afford binuclear Pd(III) complexes featuring a Pd-Pd bond.

238 agmentation of an initially formed, formally binuclear Pd(III), intermediate.

239 A new nano optical sensor binuclear Pd-(2-aminothiazole) (urea), Pd(atz,ur) comple

240 The new binuclear phenoxyiminato zirconium complex {1,7-(O)2C10H

241 nally designed butterfly-like phosphorescent binuclear platinum complexes that undergo controlled PSC

242 rivatives with regard to tetranuclear versus binuclear product formation is proposed to be connected

243 The binuclear Pt (pca)(bpy) has +II net charge which is very

244 escence intensity of the nano optical sensor binuclear Pt(pca) (bpy) at 528nm after excitation at 370

245 the luminescence intensity at 528nm of nano binuclear Pt(pca) (bpy) doped in sol-gel matrix by vario

246 tween 3-nitrotyrosine and the optical sensor binuclear Pt-2-pyrazinecarboxylic acid (pca)-Bipyridine

247 clear (RAs-Fe = 2.88-2.94 A) and monodentate binuclear (RAs-Fe = 3.35-3.41 A) complexes with Fe, thus

248 DFT modeling of the binuclear reaction pathway of the O-O bond formation in

249 me c oxidase from the cellular inside to the binuclear redox center (BNC) can occur through two disti

250 ion of halide-bridged structures establishes binuclear reductive elimination as a viable mechanism fo

251 involve all monomeric Rh intermediates and a binuclear Rh intermediate in the other case, are propose

252 it quantitative comparisons with related 2D, binuclear Ru(II) ammine complex salts.

253 investigated DNA threading intercalation by binuclear ruthenium complex [mu-dppzip(phen)4Ru2](4+) (P

254 dent threading intercalation kinetics of the binuclear ruthenium complex Delta,Delta-[mu-bidppz-(phen

255 The dumbbell shaped binuclear ruthenium complex DeltaDelta-P requires transi

256 me, was investigated using a new photoactive binuclear ruthenium complex, [Ru(bipyrazine)2]2(quaterpy

257 Here, we characterize a family of binuclear ruthenium compounds that selectively target th

258 cal form of the cross-linked tyrosine in the binuclear site may be more significant in the catalytic

259 onstraints on the geometry and energy of the binuclear site of both R2-wt and variant R2s are also ex

260 of binding of formate to the heme a(3-)Cu(B) binuclear site of bovine cytochrome c oxidase has been o

261 to state O is initiated by hydration of the binuclear site.

262 iating the transfer of copper into the Cu(A) binuclear site.

263 nodentate end-on-bound O2 to one iron in the binuclear site.

264 tate, suggesting that the cobalt ions in the binuclear sites are not magnetically coupled.

265 an be classified into coupled and noncoupled binuclear sites based on the magnetic interaction betwee

266 on is very low, there is a small fraction of binuclear sites in EcMetAP formed through cooperative bi

267 In other cases a binuclear species can persist through the catalytic cycl

268 In contrast, monodentate binuclear species of (-O)2-COHx=[0,1], are expected to f

269 especially induced by the double protonated binuclear species.

270 d(I) mechanism, involving an iodide-assisted binuclear step to release the product.

271 ate the dynamical flexibility of the bridged binuclear structural motif in the active site of arginas

272 luster, that has unusual ligands to an Fe-Fe binuclear subcluster: CN(-), CO, and an azadithiolate (a

273 The binuclear subsite Fe2(adt)(CO)3(CN)2 is attached through

274 ydrogenase with a selectively (57)Fe-labeled binuclear subsite is described.

275 ved in addition to the majority of bidentate binuclear surface complexes on a wet paste sample prepar

276 lanolytic chain-transfer processes, with the binuclear system exhibiting a sublinear relationship bet

277 orporation of electroactive units into these binuclear systems has been pursued, affording multicompo

278 nct metal sites (T1 in domain 3, T2, and the binuclear T3 at the interface between domains 1 and 3).

279 in the RO form of a high-potential MCO, the binuclear T3 Cu(II) site can be reduced via the 700 mV T

280 Alternatively, when this fully reduced binuclear T3 site is oxidized via the T1 Cu, a different

281 four Cu atoms, including T1, T2, and coupled binuclear T3 sites.

282 ononuclear eta(1)-superoxo species, and then binuclear trans-mu-1,2-peroxo-bridged complexes.

283 luding gliZ, encoding a putative Zn(2)Cys(6) binuclear transcription factor.

284 tic applications, allow us to propose that a binuclear transmetalation intermediate is the reactive s

285 r Cu cluster composed of a type 2 (T2) and a binuclear type 3 (T3) site that together catalyze the fo

286 unction with a mononuclear Type 2 (T2) and a binuclear Type 3 (T3) site, arranged in a trinuclear cop

287 xidized), because the type 2 and the coupled-binuclear type 3 Cu centers in the O(2)-reducing trinucl

288 type 1 (T1), one type 2 (T2), and a coupled binuclear type 3 Cu pair (T3).

289 ions: one type 1, one type 2, and a coupled binuclear type 3 site.

290 is reaction: the type 1, type 2, and coupled binuclear type 3 sites.

291 The coupled binuclear "type 3" Cu sites are found in hemocyanin (Hc)

292 Cu atoms: a type 1, a type 2, and a coupled binuclear, type 3 site.

293 ure, reactivity and magnetic properties of a binuclear uranium-oxo complex.

294 vel coordination sites, including an unusual binuclear zinc cluster.

295 ptor, the protease domain of PSMA contains a binuclear zinc site, catalytic residues, and a proposed

296 We show that this enzyme possesses a binuclear zinc-active site in which one of the zinc ions

297 A recognition motif domains and a C-terminal binuclear zinc-binding domain are required for mRNA bind

298 s are renowned for nucleic acid recognition, binuclear zinc-binding structural motifs, such as LIM (L

299 osphodiesterase (NPP), have nearly identical binuclear Zn(2+) catalytic centers but show tremendous d

300 Overall, the results suggest that the binuclear Zn(2+) catalytic site remains very similar bet

301 olynuclear unit consisting of an oxo-bridged binuclear ZrOCo(II) group coupled to an iridium oxide na