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1 eate) and another expressing CSH2 and PAG17 (binucleate).
2 U, or both often had enlarged nuclei or were binucleated.
3 se cells fail to undergo cytokinesis and are binucleated.
4 yokinesis, develop aneuploidy, and are often binucleated.
5 ternberg" (RS) cells, are characteristically binucleated.
6                                Most VMs were binucleated (87% versus 12% mononucleated) and larger th
7 s to Rab6-KIFL results in the cells becoming binucleate after one cell cycle, and time-lapse microsco
8 se-dead mutant causes an increased number of binucleate and multinucleate cells, suggesting that the
9   Furthermore, we observed a large number of binucleated and apoptotic cells-signs of failed cytokine
10 furrow dynamics during cytokinesis producing binucleated and enucleated cells.
11                              The presence of binucleated and multinucleated cells, reminiscent of lar
12                             M phase entry of binucleated and S phase entry of mononucleated cells wer
13  degrees C, defective scd1-1 guard cells are binucleate, and the formation of their ventral cell wall
14        Rat and sheep cardiac myocytes become binucleate as they complete the 'terminal differentiatio
15 dividing cells with lagging chromatin become binucleated as a consequence of unstable bridges.
16  Fgama1 mutant produced oval, single-celled, binucleated ascospores by selfing.
17                Induced cardiomyocytes became binucleate, assembled sarcomeres and had cardiomyocyte-l
18  found that both embryonic and postnatal CMs binucleate at a significantly higher rate when cultured
19 depleted AT2 cells in two phases, mitosis of binucleated AT2 cells followed by replication of mononuc
20 populations, including uninucleate (UNC) and binucleate (BNC) cells that are most abundant in the cot
21 ay 21; 5% (rodent) to 25% (human) cells were binucleated by day 21.
22 red with high frequency in cells that became binucleated by furrow regression, but not in cells that
23 confocal microscopy to quantify formation of binucleated cardiomyocytes and cardiomyocytes with polyp
24 wth-restricted (IUGR) fetal sheep have fewer binucleated cardiomyocytes, reflecting a more immature h
25          NRG1 induces mononucleated, but not binucleated, cardiomyocytes to divide.
26 s elongation and inhibited trophoblast giant binucleate cell differentiation as observed on day 16.
27 f the mitotic checkpoint in one spindle of a binucleate cell failed to arrest cytokinesis induced by
28 oscopy revealed that loss of Tek2 results in binucleate cell formation by aberrant fusion of daughter
29 es cytokinesis arrest in cancer cells, where binucleate cell formation occurs after mitosis takes pla
30 nd CaM also promotes cytokinesis failure and binucleate cell formation.
31 firmed AP-2alpha variants in ovine chorionic binucleate cell nuclear extracts, one of which migrates
32  I protection analysis using ovine chorionic binucleate cell nuclear protein, identified 19 footprint
33 of His2Av/H2A.z also suppressed the Myb-null binucleate cell phenotype, suggesting a novel role for t
34 ng the eukaryotes, including its distinctive binucleate cell structure.
35                         We estimate that the binucleate cell-expressed PAG originated 52 +/- 6 millio
36 amaged lymphocytes with multiple micronuclei/binucleated cell, whereas partial-body exposures produce
37  In normal cultures, highly spread pigmented binucleate cells (type 3) bound and rapidly ingested mul
38 ogical differentiation included formation of binucleate cells and infrequent multinucleate syncytia,
39 14-3-3sigma impairs mitotic exit to generate binucleate cells and provides a potential explanation of
40 Time-lapse videomicroscopy demonstrated that binucleate cells are delayed in the first growth phase o
41 asin to block cleavage, we confirm that most binucleate cells arrest in G1.
42                  Therefore, we used Myb-null binucleate cells as a quantitative phenotypic readout of
43 lactin gene family, is produced by chorionic binucleate cells at the maternal-fetal interface, and is
44  stage of cytokinesis but fused back to form binucleate cells because of the absence of the midbody m
45  stimulated an increase in footprint area of binucleate cells but Ang II did not.
46  forced expression of activated mDia2 yields binucleate cells due to failed cytokinesis, and 4) the c
47 mline cell morphology, we determined whether binucleate cells form by defective cytokinesis or by fus
48     Surprisingly, up to 50% of the resulting binucleate cells generated colonies.
49 have a "tetraploidy checkpoint" that arrests binucleate cells in G1, thereby preventing their propaga
50  cappuccino, and chickadee mutants contained binucleate cells in which ring canal remnants stained wi
51 the endometrial LE and GE, as well as in the binucleate cells of the conceptus.
52 nceptuses, enJSRV RNAs were also detected in binucleate cells of the trophectoderm.
53                               The progeny of binucleate cells progressively dropped out of the cell c
54 ersification of PAG expressed in trophoblast binucleate cells seems to have been associated with the
55 concentrations of cytochalasin, we find that binucleate cells undergo DNA synthesis and later proceed
56 n of abscission does not appear to result in binucleate cells, but in apoptosis.
57 ealed specific expression in the trophoblast binucleate cells, consistent with a role in the formatio
58 te stage of cytokinesis and the formation of binucleate cells, mirroring the defects resulting from a
59 lted in cytokinesis failure and formation of binucleate cells, or by chemical inhibition of Aurora ki
60 cts in nuclear morphology, and appearance of binucleate cells, revealing an essential role for SENP5
61                             In most of these binucleate cells, the damaged nucleus arrested prior to
62                             We now show that binucleate cells, the hallmark phenotype of cytokinesis
63                           Furthermore, using binucleate cells, we show that exit from mitosis occurs
64 m to eliminate one of the two centrosomes in binucleate cells, we show that the unaltered array is ra
65 demonstrated by an increase in the number of binucleate cells.
66 ctivation of the oPL gene in ovine chorionic binucleate cells.
67 mbers that are expressed only in trophoblast binucleate cells.
68 Ns in the ;garland' and to their fusion into binucleate cells.
69 se-1 at the midbody, and the accumulation of binucleate cells.
70 ate cells arose through aberrant division of binucleated cells and displayed abnormal metaphase plate
71 ion of T37V mutant of Cdc6 (Cdc6-TV) induces binucleated cells and incompletely separated nuclei.
72 s that describe micronuclei distributions in binucleated cells and serve as predictors in machine lea
73   Finally, we describe a phenomenon by which binucleated cells are resolved via cytokinesis into two
74          Time-lapse microscopy revealed that binucleated cells arise by incomplete abscission of prog
75 term imaging experiments indicated that most binucleated cells arose through a bipolar mitosis follow
76  delays abscission and prevents formation of binucleated cells by stabilizing the cytokinetic interce
77       We observed that spontaneously arising binucleated cells exhibited chromosome mis-segregation r
78 ed to the coculture system were recovered as binucleated cells expressing an epithelial surface epito
79 ted cardiomyocytes; under resting conditions binucleated cells had a functional profile suggestive of
80  of WNT activity increases the percentage of binucleated cells in Hep-Orgs, an effect that is depende
81 o increase the prevalence of micronuclei and binucleated cells in parallel with aberrant mitotic chec
82  to a mitotic defect, resulting in unstable, binucleated cells in vitro and in vivo.
83 for mitosis, or arrested in cytokinesis, and binucleated cells in which nuclear division had occurred
84                                              Binucleated cells proliferate slowly.
85                                              Binucleated cells were also detectable in primary murine
86  are arrested in the cell cycle as septated, binucleated cells with highly condensed chromatin, fragm
87 before arresting as elongated, predominantly binucleated cells with incompletely segregated chromosom
88 icronuclei/cell probability distributions in binucleated cells, and used them as predictors in random
89 ugh RNA interference leads to an increase in binucleated cells, implicating its reduced expression in
90 pression is accompanied by the appearance of binucleated cells, indicating the process of cell divisi
91 was sufficient to elicit donut formation and binucleated cells, whereas blocking proteasomal degradat
92 e of cytokinesis leading to the formation of binucleated cells.
93 esulted in a large increase in the number of binucleated cells.
94 s cytokinesis, resulting in the formation of binucleated cells.
95 as often incomplete after mitosis, producing binucleated cells.
96 MILR knockdown resulting in ~10% increase in binucleated cells.
97 her rate of cytokinesis failure resulting in binucleated cells.
98 lure of cytokinesis, and increased number of binucleated cells.
99 fibroblasts cultured from Spg20-/- mice, and binucleated chondrocytes were prominent in epiphyseal gr
100                      The macronucleus of the binucleate ciliate Tetrahymena thermophila contains frag
101 rogress through cytokinesis and subsequently binucleate, consistent with published reports of in vitr
102                          Intensity ratios of binucleated CPCs with bromodeoxyuridine of >/=70:30 betw
103 roblem and cytokinesis defects, resulting in binucleate daughter cells.
104 lasia as evidenced by an increased number of binucleated epithelial cells and a marked elevation in c
105 thm to accurately identify and quantify rare binucleated erythroblasts (BNEs) in dyserythropoietic BM
106                   Bone marrow studies showed binucleated erythroblasts and erythroblasts with cytopla
107 binucleate NSCs and neurons elevate p53, but binucleate fibroblasts do not.
108              Giardia lamblia is an anaerobic binucleate flagellated protozoan known to lack de novo s
109 In RPE1 cells, 90% of colonies obtained from binucleate founders had a karyotype that matched the par
110  Kirre (Duf) and Sns are co-expressed within binucleate garland cell nephrocytes (GCNs) that contribu
111 cells grew approximately 5 times faster than binucleate germlings.
112 ll in classical Hodgkin lymphoma (HL) is the binucleated giant Reed-Sternberg cell.
113 (2) (4-) cavity holding a single metal, to a binucleating H(2) ema(2-) with bridging sulfurs and carb
114 s not occur because cells are polyploid, are binucleate, have multiple centrosome, or have failed cyt
115 hly proliferative, with decreased numbers of binucleate hepatocytes and increased nuclear polyploidy.
116 increase in steatosis score, and presence of binucleate hepatocytes and positive cells for AlkP in pe
117  of miRNAs resulted in a 3-fold reduction in binucleate hepatocytes, indicating that miRNAs regulate
118 sm or is confined to the nucleus, we created binucleate heterokaryon yeast cells in which one nucleus
119  disease, with ~0.4% of Purkinje cells being binucleate heterokaryons.
120 rkinje neurons resulting in the formation of binucleated heterokaryons.
121 ogerin/LADelta50-expressing normal cells are binucleated, implicating progerin/LADelta50 as causing s
122 g to the majority of cardiomyocytes becoming binucleated instead of generating 2 daughter cells with
123 ared in small mononucleated (SMMs) and large binucleated (LBMs) myocytes.
124 Co(2+)(H(2)O)](+), contains an unsymmetrical binucleating ligand (oxapyme) which provides five- and s
125                  Complexes incorporating the binucleating ligand N[omicron-(NHCH2P(i)Pr2)C6H4]3 with
126                                        A new binucleating ligand scaffold is introduced that supports
127 nion can be stabilized through creation of a binucleating ligand that enforces a tightly constrained
128 PR(2+) are initially self-assembled from the binucleating ligand, 3,6-bis(5-methyl-2-pyridine)-1,2,4,
129 rplanar torsional twisting, driven by chiral binucleating ligands in highly conjugated molecular wire
130                     MN frequency in maternal binucleated lymphocytes was found to increase with BTHM
131 may increase the frequency of MN in maternal binucleated lymphocytes.
132 plasmic bridges, and nuclear buds) per 1,000 binucleated lymphocytes.
133  [Cu(II)(2)(XYLO)(O(2)(*-))](2+) (1) (XYLO = binucleating m-xylyl derivative with a bridging phenolat
134                                            A binucleating macrocycle was prepared which specifically
135 urred in association with podocytes becoming binucleate (mitotic podocyte catastrophe) and subsequent
136 rrested with multiple buds, several SPBs and binucleate mother cells.
137 idine (BrdU) uptake) separately in mono- vs. binucleate myocytes.
138  myocytes; (3) PE is a hypertrophic agent in binucleate myocytes; and (4) the ERK cascade is required
139 id not significantly alter the proportion of binucleated myocytes or cell cycle activity in either ve
140 roximately 70% (P < 0.05); the proportion of binucleated myocytes was also lower in UPE fetuses at th
141                                              Binucleated myocytes were 12% and 25% larger in WT than
142 onal state (as measured by the proportion of binucleated myocytes) and cell cycle activity (as measur
143 e that fail show a tissue-specific response: binucleate NSCs and neurons elevate p53, but binucleate
144  of membrane structures and the formation of binucleate nurse cells.
145 that nucleolin-colocalizing cells were often binucleated or apoptotic, suggesting that the presence o
146       Second, LMW-E-overexpressing cells are binucleated or multinucleated with amplified centrosomes
147 n, mononuclear diploid cardiomyocytes become binucleated or polyploid and exit the cell cycle.
148 failure leads to incomplete abscission and a binucleate outcome.
149                                          The binucleate pathogen Giardia intestinalis is a highly div
150                       We observed a striking binucleated phenotype in miR-1300 transfected cells due
151                                              Binucleated polyploid cells are common in many animal ti
152                            Mononucleated and binucleated polyploid hepatocytes (4n, 8n, 16n and highe
153 ranyl cation and a rare-earth trication in a binucleating polypyrrole Schiff-base macrocycle (Pacman)
154                         Giardia lamblia is a binucleate protistan parasite causing significant diarrh
155 termine if similar increase in the number of binucleated Purkinje neurons, occurs in children that re
156 del for cellular and molecular biology, is a binucleated single-celled organism with a germline micro
157 were normal but the rest had arrested at the binucleate stage of development, were small, pear-shaped
158        Microspores at late uninucleate/early binucleate stages were isolated from flower buds of toba
159                                 Cells became binucleated, suggesting a failure of cytokinesis, and mi
160                                              Binucleate tetraploid cells that formed after incubation
161 range of different nuclear morphologies from binucleated to multimicronucleated.
162                                    Initially binucleate, trimeras underwent coordinated nuclear divis
163 ccumulate specifically in pollen at the late binucleate/trinucleate stage of development rather than
164  change their expression oppositely in mouse binucleate ventricular cardiomyocytes during development
165 at did not complete cytokinesis and remained binucleated were found to be CDC20(low)SPG20(high) while
166        MOX4 is identical to UPC2, encoding a binucleate zinc cluster protein controlling expression o

 
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