ライフサイエンスコーパス: bioactive

1 sition and curcumin was a model encapsulated bioactive.

2 as a source of antioxidants, colorants, and bioactives.

3 extraction of some components, including the bioactives.

4 organo-boronate esters and boron containing bioactives.

5 r nanocarrier systems for brain targeting of bioactives.

6 Early measurement of bioactive adrenomedullin is a strong predictor of the ne

7 Elevated bioactive adrenomedullin was also associated with a prol

8 The stability of the bioactives after 60 days storage at 25 degrees C was als

9 is a powerful way to control the release of bioactive agents and imaging probes.

10 Data from our group reports that bioactive agents in soy and tomatoes can reduce pro-infl

11 rocess that underpins the development of new bioactive agents.

12 m reaction modes to generate fluorophores or bioactive agents.

13 oflavone glycosides into their corresponding bioactive aglycones was observed in fermented beverage.

14 The synthesis of valuable bioactive alicyclic amines containing variable substitue

15 omplexity are attractive for identifying new bioactive amine chemical space.

16 Chocolate is an important source of free bioactive amines and amino acids which play important ro

17 cteristics and levels of methylxanthines and bioactive amines of cocoa.

18 cogenes in tumor development, the release of bioactive amines, and indolent growth of the tumors.

19 common critical process in the metabolism of bioactive amino compounds.

20 cently, increasing interest has been paid to bioactive and electronic sutures made of synthetic polym

21 A novel photocrosslinkable, hybrid bioactive and inherently conductive bioink formed from p

22 Instead, HMOs act as a bioactive and prebiotic enriching HMO-utilizing bacteria

23 Saponins are known for their bioactive and surfactant properties, showing applicabili

24 occur as a result of interactions of native bioactives and carriers.

25 at globule membrane (phospholipids and other bioactives), and other micronutrients (Ex + MFMD, n = 12

26 to obtain the full benefit of the nutrients, bioactives, and antioxidants that they contain, together

27 Here, we report that NMP is a bioactive anti-inflammatory compound well tolerated in v

28 f citrus bio-wastes and utilization of their bioactives as therapeutic agents and in functional food

29 The need for a bioactive attachment substrate also hinders progress.

30 talysis was developed that generates various bioactive beta,beta-diaryl propanoate derivatives.

31 Certain bioactive breast milk proteins and HMOs are associated w

32 Human milk oligosaccharides (HMOs) and bioactive breast milk proteins have many beneficial prop

33 In this study, highly bioactive Ca-silicate (CSi) bioceramic scaffolds were fa

34 derstanding the mechanism of action (MOA) of bioactive chemicals in terms of targeted signaling pathw

35 Through a screen of known bioactive chemicals in zebrafish, we identified a new pa

36 on, resulting in the formation of mature and bioactive CLE40 in planta.

37 Curcumin is an important bioactive component of turmeric and also one of the impo

38 omposition and human milk macronutrients and bioactive components and also their association with inf

39 e Us process increases the levels of healthy bioactive components.

40 is review describes nutritional, mineral and bioactive composition of the chicory plant and summarize

41 vailable concerning their nutritional and/or bioactive composition.

42 ) had no effect on the content in ASE of the bioactive compound corotoxigenin-3-O-glucopyranoside; co

43 ovide stable, biocompatible isolation of the bioactive compound from its surroundings with minimal in

44 aracterizes the physicochemical, sensory and bioactive compound traits of twenty-two sweet cherry acc

45 embly of these fragments provided a specific bioactive compound with improved potency that inhibits p

46 nal apples and favored their enrichment with bioactive compounds (AOA = +11.5%).

47 The determination of the profile of bioactive compounds (phenolic compounds, flavonoids, tan

48 Antibodies conjugated to bioactive compounds allow targeted delivery of therapeut

49 and ohmic heating (OH) for the extraction of bioactive compounds and analyzed for total phenolic cont

50 urated azacycles are commonly encountered in bioactive compounds and approved therapeutic agents.

51 foam mat drying (TWPC-FMD) and compared its bioactive compounds and nutrients contents.

52 main objective of this study was to compare bioactive compounds and other important quality paramete

53 capsulation technique to stabilize sensitive bioactive compounds and sometimes enhances their perform

54 this work was to characterize the profile of bioactive compounds and the antioxidant activity of inod

55 In this study, it was aimed to determine the bioactive compounds and volatile aroma compounds of the

56 than half of all antibiotics and many other bioactive compounds are produced by the actinobacterial

57 cestral nutritional grain and good source of bioactive compounds as peptides.

58 ith antioxidant systems, gene expression and bioactive compounds at harvest and during cold storage w

59 of inspiration towards the discovery of new bioactive compounds based on novel molecular scaffolds.

60 , micronutrients, and other health-promoting bioactive compounds contained in nuts and dried fruits m

61 and new insights regarding ncRNAs as dietary bioactive compounds could remodel our understanding abou

62 Bioactive compounds demonstrating antioxidant activity w

63 Apart from the beneficial bioactive compounds found in this food (e.g. polyphenols

64 Objective of this study was to recover bioactive compounds from grape pomace, and to investigat

65 significantly influenced the profile of the bioactive compounds identified, and the antioxidant capa

66 LC(+mcra) can generate bioactive compounds in larger quantity including conjuga

67 tions stimulate the accumulation of relevant bioactive compounds in olives, contributing to increasin

68 ts to be a valuable source of nutritious and bioactive compounds in our daily diet.

69 l activities associated with the presence of bioactive compounds in the different plant parts.

70 r and the amounts of nutrients, minerals and bioactive compounds in the juices of 16 apple varieties

71 ents, fatty acids composition, proteins, and bioactive compounds in the seeds of these species were i

72 One of the major classes of bioactive compounds is plant polyphenols.

73 tic acid bacteria to enrich the portfolio of bioactive compounds of avocado fruit (Persea americana M

74 In the present research, the main bioactive compounds of H. dulcis pseudofruits were chara

75 obial secondary metabolism is a reservoir of bioactive compounds of immense biotechnological and biom

76 The contents of individual bioactive compounds of in this fruit fraction of Saskato

77 nt materials produced different stability of bioactive compounds of red ginger extract powder.

78 affected the physiochemical composition and bioactive compounds of seeds.

79 Reduction of bioactive compounds sensitive to heat, light and oxygen

80 ing alternative system for supplying several bioactive compounds simultaneously, among them polypheno

81 ocactus, Hylocereus, and Stenocereus contain bioactive compounds such as betalains and phenols.

82 although the grain is an important source of bioactive compounds such as phenolic compounds (PCs).

83 The plant is a useful source of essential bioactive compounds such as steroids, flavonoids and phe

84 , produces fruit known as prickly pears with bioactive compounds that are associated with health bene

85 Flavan-3-ols are a group of bioactive compounds that have been shown to improve vasc

86 fluid (fed state) facilitated the release of bioactive compounds to gastrointestinal fluid.

87 lternative to increase the concentrations of bioactive compounds while reducing the amount of sugar u

88 Therefore, bioactive compounds, antioxidant activities and sensory

89 e urea functionality is inherent to numerous bioactive compounds, including a variety of clinically a

90 verse effects associated with the release of bioactive compounds, including toxic cyanopeptides.

91 essments of their cellular interactions with bioactive compounds, particularly in a kinetic format, a

92 rinated alkyl groups are important motifs in bioactive compounds, positively influencing pharmacokine

93 usion, S. minor could be a source of natural bioactive compounds, while fertilization could increase

94 a genus show promise as sources of desirable bioactive compounds.

95 mechanisms that amplify cellular response to bioactive compounds.

96 ndicating this species was making additional bioactive compounds.

97 excellent means to deliver health-promoting bioactive compounds.

98 verarching strategy for the synthesis of new bioactive compounds.

99 times (60 s) resulted in higher retention of bioactive compounds.

100 vatives are prevalent in pharmaceuticals and bioactive compounds.

101 to enhance stability and bioaccessibility of bioactive compounds.

102 apsulation technologies to protect sensitive bioactive compounds.

103 c analyzes were applied for isolation of the bioactive compounds.

104 C, 30 min), to increase the preservation of bioactive compounds.

105 omplex from Lippia citriodora leaves rich in bioactive compounds.

106 , mainly due to differences in the levels of bioactive compounds.

107 s) are emulsion-based carriers of lipophilic bioactive compounds.

108 d compared towards the selective recovery of bioactive compounds.

109 Brassica spp. are excellent sources of bioactive compounds.

110 ity and increase the stability of functional bioactive compounds.

111 rtant for preserving a high concentration of bioactive compounds.

112 Processing did not cause much reduction of bioactive constituents and antioxidant activity of APIp.

113 urrent study was carried out to evaluate the bioactive constituents and physical properties of fourte

114 aceutical properties of olives and olive oil bioactive constituents contributed to oliviculture recen

115 Prickly pear is a vital source of bioactive constituents such as phenolic and antioxidant

116 e collection season significantly affect the bioactive content and the antioxidant potential of olive

117 tion proportions (S(K), S(Ca), S(Mg)) on the bioactive content of hydroponically cultivated lettuce w

118 tro study may support the notion that coffee bioactives contribute to antioxidant defense and detoxif

119 one of many peptides that could benefit from bioactive cyclization, a strategy that is amenable to br

120 we demonstrate that RALF peptides fold into bioactive, disulfide bond-stabilized proteins that bind

121 ) in order to monitor the formation of these bioactives during the elaboration process.

122 ot been evaluated, and data concerning their bioactive effects are scarce.

123 This group of bioactive elastin peptides presents the XGXPGXGXG consen

124 this study illustrate the beneficial effect bioactive factors and PET incorporation have on ACL rege

125 -suppressing mechanism, via the secretion of bioactive factors by mammary cells, that is present in d

126 also a dynamic endocrine organ that secretes bioactive factors into blood plasma.

127 In addition to providing nutritional and bioactive factors necessary for infant development, huma

128 er to pre-weaned calves, which are devoid of bioactive factors with immunological roles.

129 Flavones are important bioactive flavonoids in cereal grains, but are poorly ch

130 ously demonstrated that pyrazinoic acid, the bioactive form of the prodrug pyrazinamide (PZA), interr

131 re short peptides that are locked into their bioactive form using a synthetic brace.

132 Lutein is a bioactive found in dark leafy vegetables that may be use

133 d be rescued by the exogenous application of bioactive GA(4), confirming that CsGA1ox/ds catabolizes

134 e isolation of pentagalloyl glucose (PGG), a bioactive gallotannin.

135 icating that this enzyme variant can produce bioactive GAs in planta Furthermore, a genetically modif

136 oxidase, and its mutation leads to increased bioactive gibberellin content, enhanced cutin and wax bi

137 Bioactive gibberellins (GAs) are central regulators of p

138 Furthermore, Si-containing bioactive glass biomaterials have positive effects on bo

139 ive cake (POC), a by-product that is rich in bioactive health-promoting compounds.

140 ation of inherently conductive polymers with bioactive hydrogels using bi-functional monomers such as

141 AD-base Coa exhibited a sustained release of bioactive IGF-1 over 3 weeks.

142 8BP is dysregulated, abnormal levels of free bioactive IL-18 are detected, such as in the sera of Il-

143 due to increased surface area available for bioactive inclusion.

144 nscious about healthy food products based on bioactive ingredients in order to protect against diseas

145 peutic attributes due to their highly-valued bioactive ingredients.

146 od candidates to evaluate their potential as bioactive ingredients.

147 and functional benefits for encapsulation of bioactive ingredients.

148 Therefore, bioactive insect extracts can be selectively obtained by

149 ntification of off-targets and prediction of bioactive interactions by nature of ligand recognition o

150 d DNA by upregulation of ISGs and release of bioactive interferon.

151 ion of samples allowed the identification of bioactive intermediates by measuring the antibiotic acti

152 (EDA) was applied for the identification of bioactive intermediates of azithromycin (AZI) and ciprof

153 diabetes mellitus (T2DM) and contain potent bioactive isothiocyanates.

154 hift entails a model in which a reduction of bioactive leptin levels in the context of obesity trigge

155 nces and frequencies, magnetic elements, and bioactive ligands to remotely regulate numerous host cel

156 n, and this makes the uniform conjugation of bioactive ligands very challenging.

157 ken together, our results establish that the bioactive lipid LPA drives the expression of TNF-alpha t

158 s of N-acylethanolamines (NAEs), a family of bioactive lipid mediators.

159 We demonstrate that bioactive lipid profiles can be readily detected from th

160 kdown keratinocytes, we pinpointed candidate bioactive lipid subspecies as differentiation regulators

161 tion of intramuscular triglyceride; however, bioactive lipids such as diacylglycerols and sphingolipi

162 The N-acyl amino acids are a family of bioactive lipids with pleiotropic physiologic functions,

163 ipase D autotaxin (ATX), which generates two bioactive lipids, lysophosphatidic acid (LPA) and sphing

164 nts of a panel of pro- and anti-inflammatory bioactive lipids, we measure the profile changes upon ad

165 The encapsulation of bioactive lipophilic compounds by complex coacervates of

166 o-sized, MVs packaged with a select array of bioactive macromolecules and they have been shown to pla

167 racellular matrix encompasses a reservoir of bioactive macromolecules that modulates a cornucopia of

168 ular stomatitis virus G protein (VSV-G) with bioactive macromolecules via split GFP complementation.

169 llular signaling pathways, and production of bioactive mediators.

170 ticancer activity of noscapine arises from a bioactive metabolite that binds to the colchicine site o

171 out the sources and metabolism of NO and its bioactive metabolites (NOx) in both normal and complicat

172 emistry that plants use to generate complex, bioactive metabolites from simple amino acids.

173 However, examples of conjoined roles of bioactive metabolites produced by the same organism rema

174 itory neurotransmission and may also produce bioactive metabolites.

175 y-based metabolomics targeting nutrients and bioactive metabolities.

176 is that short-chain fatty acids (SCFAs), key bioactive microbial metabolites, are the missing link al

177 The presented approach to design bioactive microcarriers offer sustained sequential deliv

178 materials, or that integrate living cells or bioactive moieties, can respond to a range of environmen

179 The combination of more than one bioactive moiety in a multitargeted anticancer agent may

180 ese responses, which contributes to superior bioactive molecular delivery.

181 pplied to the late-stage modification of the bioactive molecule dehydropregnenolone.

182 ternary carbon positioned at the center of a bioactive molecule offers conformational rigidity, which

183 d is showcased with the short synthesis of a bioactive molecule.

184 sm along several pathways, resulting in many bioactive molecules acting in various organs through dif

185 Photoactivation of bioactive molecules allows manipulation of cellular proc

186 which are highly valued structural motifs in bioactive molecules and chemical sensors.

187 Using this method, three routes toward bioactive molecules are improved in terms of yield and/o

188 In these experiments, the bioactive molecules are turmeric, a dried rhizome of Cur

189 neural recording, stimulation and sensing of bioactive molecules at the electrode-tissue interface.

190 the scalable and facile synthesis of complex bioactive molecules carrying O-sulfates remains challeng

191 he most ideal positron emitters for labeling bioactive molecules for molecular imaging studies.

192 as a key driving force behind the release of bioactive molecules from supramolecular gels, this work

193 In this investigation, we docked bioactive molecules of tea onto the active site of Nsp15

194 c intermediates for the synthesis of diverse bioactive molecules such as glutaric and delta-aminovale

195 sphingolipid family, a diversified class of bioactive molecules that mediate many biological process

196 interact, encapsulate and eventually release bioactive molecules through an erosion-based process.

197 s exposed to HS has the potential to shuttle bioactive molecules to recipient cells and make them rob

198 t-rich fibrin (PRF) serves as a reservoir of bioactive molecules to support wound healing and bone re

199 verse aryl halide derivatives, including the bioactive molecules vismodegib and PH089.

200 e involves the efficient delivery of natural bioactive molecules with anti-cancer effects via a bioph

201 CD(3)-containing products, derivatization of bioactive molecules, and chemoselective reduction in the

202 most prevalent structural elements found in bioactive molecules, and so this synthetic approach simp

203 n important chemical code widely existing in bioactive molecules, but the scalable and facile synthes

204 aterials for the delivery of a wide range of bioactive molecules, from small hydrophobic drugs to lar

205 Partitioning of bioactive molecules, including drugs, into cell membrane

206 e introduction of complex alkoxy groups into bioactive molecules, providing a practical new tool with

207 Benzophenone (BP) is present in a variety of bioactive molecules.

208 f (R)-muscone paves the path to design other bioactive molecules.

209 al groups and heterocycles commonly found in bioactive molecules.

210 e protein superfamily in the biosynthesis of bioactive molecules.

211 using synthetic biology to engineer diverse bioactive molecules.

212 d structure-activity relationships for these bioactive molecules.

213 hetic gene clusters are a valuable source of bioactive molecules.

214 NAPEs are lipid precursors for bioactive N-acylethanolamines (NAEs) that are involved i

215 This bioactive natural product class is reported for the firs

216 These 'rare' sugars feature prominently in bioactive natural products and pharmaceuticals, includin

217 ORPphilins are bioactive natural products that strongly and selectively

218 h due to the prevalence of aryl thioether in bioactive natural products, functional materials, agroch

219 Some bacteria produce bioactive neurotransmitters that have previously been pr

220 ost cellular kinases to yield ultimately the bioactive nucleoside analogue triphosphates (NTP).

221 Bioactive nutrients can alter the composition and metabo

222 is expected to facilitate the preparation of bioactive organic molecules.

223 steoclast differentiation and the release of bioactive osteocalcin in the general circulation.

224 ondria (Mt) and the Mt-genome-encoded, small bioactive peptide humanin (HN).

225 ase both intact Mt and humanin (HN), a small bioactive peptide normally transcribed from the Mt genom

226 elation to heat-damage and occurrence of the bioactive peptides beta-casomorphins (BCMs).

227 nd to investigate their capacity to generate bioactive peptides during milk fermentation.

228 This study was aimed to produce bioactive peptides from optimally fermented tempe, and m

229 oduct can be processed to obtain calcium and bioactive peptides from the separated bones and meat res

230 Injection of the bioactive peptides into slugs triggered defensive behavi

231 llent structural framework for deposition of bioactive peptides of the ECM, and their intrinsic bioph

232 Evidence suggests that these bioactive peptides play a role in the regulation of meta

233 that the crosslinked emulsion is a source of bioactive peptides that are liberated by human digestive

234 red ham constitutes a good source of natural bioactive peptides that have potential benefit for human

235 Enzymatic hydrolysis of proteins produces bioactive peptides that have the potential to provide he

236 actic acid bacteria (LAB) and yeasts produce bioactive peptides with a positive effect on human healt

237 is of the fish bycatch allows the release of bioactive peptides with potential use in the food indust

238 The increasing interest in bioactive peptides with therapeutic potentials has been

239 ion of sparse networks where nodes represent bioactive peptides, and edges between two nodes denote t

240 r representing a chemical reference space of bioactive peptides, having an implicit knowledge that is

241 towing rigidity and proteolytic stability on bioactive peptides.

242 ss of building blocks for novel analogues of bioactive peptides.

243 cover new insights from the "ocean" of known bioactive peptides.

244 hat go beyond the metabolic stabilization of bioactive peptides.

245 materials can be utilized as a scaffold for bioactive peptides; however, it may be advantageous to d

246 Semisynthetic artemisinins and other bioactive peroxides are best known for their powerful an

247 o their effects on the general compositions, bioactive phenolic compounds and antioxidant potentials

248 t may be a novel source of dietary fibre and bioactive phenolic compounds.

249 It bound to multiple bioactive phosphoinositides in vitro.

250 n, this study proclaims that higher level of bioactive phytochemical, mahanine in MK leaves depending

251 t in the search for natural encapsulants for bioactive phytochemicals.

252 Bioactive plant extracts have been used for the preventi

253 Apples are rich in bioactive polyphenols and fiber.

254 ted by cherry pomace that can be a source of bioactive polyphenols.

255 actionation was more efficient for obtaining bioactive pomace constituents as compared with conventio

256 both factors had no additional effect on the bioactive potential of yogurts.

257 f degenerative chronic diseases due to their bioactive profile.

258 The nutritional and bioactive properties as well as key enzymatic activities

259 ell (NPYC) and stability of thymoquinone and bioactive properties of all samples were evaluated.

260 Phenolic compounds contribute to the bioactive properties of olive oil.

261 his study, the chemical characterization and bioactive properties of S. minor cultivated under differ

262 kernel exhibits more phenolic compounds with bioactive properties than edible fraction of mango.

263 Regarding bioactive properties, it showed high antioxidant activit

264 nds, tocopherols, and organic acids, and its bioactive properties, such as antioxidant, anti-prolifer

265 The fractions showed bioactive properties, with oxidative stress amelioratory

266 sialylated HMOs), 51 individual HMOs, and 6 bioactive proteins (lactalbumin, lactoferrin, lysozyme,

267 ine associations of milk content of HMOs and bioactive proteins at 6 mo postpartum with infant growth

268 the past decades, revealing multifunctional bioactive proteins targeting the host's hemostasis and i

269 ive abundances of HMOs and concentrations of bioactive proteins with infant growth from 6 to 12 mo [c

270 Application to the synthesis of bioactive, pyrrolizine-fused 4-quinolinone, penicinotam

271 cause of high anthocyanin content and higher bioactive response, these genotypes could be recommended

272 , resulting in a homogeneous distribution of bioactive RGD and galactose ligands required for spheroi

273 A bioactive RGD-containing peptide from laminin alpha1 cha

274 Fractionation of bioactive samples identified that the chlorinated TP296

275 The development of high-strength bioactive scaffolds for in-situ repair of large bone def

276 ya koenigii (MK) leaf being a rich source of bioactive secondary metabolites has received inordinate

277 enotypic changes such as the production of a bioactive secretome, referred to as the senescence-assoc

278 toxicity model from effect concentrations of bioactive single chemicals and detected concentrations,

279 nter-individual variability in the action of bioactive small molecules from the diet is poorly unders

280 id identification of evolutionarily inspired bioactive small molecules, in particular antibiotics wit

281 say was applied to screen approximately 1500 bioactive small-molecules, including natural products an

282 Our data suggest that inclusion of bioactive solvent NMP in pharmaceutical compositions to

283 Sphingosine 1-phosphate is a bioactive sphingolipid mediator involved in various cell

284 Furthermore, other bioactive sphingolipids such as ceramide were also down-

285 Specifically, the bioactive steroid is released for 4 weeks from poly(lact

286 roductive system and be metabolised to other bioactive steroids in the fetus.

287 s changes encompassing cellular responses to bioactive stimuli and optically induced homeostasis dist

288 Melon fractions were rich in nutrients and bioactive substances and could be useful in the developm

289 nism to allow skin keratinocytes to disperse bioactive substances is via microvesicle particles, whic

290 Bioactives such as indoles, quinolines and cis-(+)-12-ox

291 ored the formation of peptides recognized as bioactive, such as alpha(S1)-CN f(24-32) and beta-CN f(1

292 ce of gamma-lactones in natural products and bioactive targets calls for suitable building blocks for

293 nic mouse model (Flpo/Frt system) expressing bioactive TGFbeta in fibroblasts, a cell population pres

294 sico-chemical characteristics to encapsulate bioactives to improve the functional foods.

295 ing and to evaluate the interactions between bioactives toward formation of process contaminants.

296 dly and sensitively to low concentrations of bioactive/toxic analytes: statistically relevant impedan

297 lular alterations induced by low levels of a bioactive/toxic compound.

298 Comparative analysis of model bioactive/toxic compounds (ouabain and CdCl(2)) demonstr

299 he development of NLC for brain targeting of bioactives with particular reference to its surface modi

300 However, together with the bioactive zone, the adsorbed bioassay medium is eluted i