ライフサイエンスコーパス: bioactive peptide

1 fied and should be considered as a potential bioactive peptide.

2 cover new insights from the "ocean" of known bioactive peptides.

3 hat go beyond the metabolic stabilization of bioactive peptides.

4 ss of building blocks for novel analogues of bioactive peptides.

5 ve oil production based on the extraction of bioactive peptides.

6 hydrolysis to identify previously unreported bioactive peptides.

7 grade caseins at low temperature and produce bioactive peptides.

8 glass slides were selectively patterned with bioactive peptides.

9 ss spectrometry and to look for and quantify bioactive peptides.

10 Cyclotides are useful scaffolds to stabilize bioactive peptides.

11 tease that inactivates enkephalins and other bioactive peptides.

12 nd adipose tissues), generates at least four bioactive peptides.

13 ics approach for the discovery of endogenous bioactive peptides.

14 overy and structure-function studies of many bioactive peptides.

15 me, to transform recombinant precursors into bioactive peptides.

16 dent metallopeptidases that metabolize small bioactive peptides.

17 ing of a number of physiologically important bioactive peptides.

18 incorporated into the structure of selected bioactive peptides.

19 tensin I, des-Arg bradykinin, and many other bioactive peptides.

20 me that converts prohormone intermediates to bioactive peptides.

21 dogenous pro-opiomelanocortin to the correct bioactive peptides.

22 me, catalyzes the COOH-terminal amidation of bioactive peptides.

23 surface enzyme that hydrolyzes BLP and other bioactive peptides.

24 ining amino acids for the rational design of bioactive peptides.

25 that were modified in a modular manner with bioactive peptides.

26 reased the intensity of whey protein-derived bioactive peptides.

27 as recently emerged as a promising source of bioactive peptides.

28 t undergo proteolytic processing to generate bioactive peptides.

29 ndustrial processing residues are sources of bioactive peptides.

30 osins on whey proteins for the production of bioactive peptides.

31 modulate the transepithelial transport of CD bioactive peptides.

32 towing rigidity and proteolytic stability on bioactive peptides.

33 affect protein digestibility and release of bioactive peptides.

34 at STP hydrolysates are potential sources of bioactive peptides.

35 nd strategies followed for the generation of bioactive peptides.

36 can serve as a bioorthogonal modification of bioactive peptides.

37 formation on sites with highest abundance of bioactive peptides.

38 onnective tissue protein extracts to produce bioactive peptides.

39 sites that, when cleaved, releases multiple bioactive peptides.

40 successfully applied in the synthesis of two bioactive peptides: 2-aminoadamantane-2-carboxylic acid

41 Moreover, bioactive peptide 25 (Ki = 9 nM) achieved oral bioavaila

42 t sense, the interaction between the main CD bioactive peptide (32-mer peptide) and some polyphenols

43 tic bacteria strain to enable the release of bioactive peptides, a high-protein yogurt with adjunct c

44 e P and thymosin-beta4, the precursor to the bioactive peptide Ac-SDKP.

45 n in a mouse model of acute colitis than the bioactive peptide alone, and showed enhanced stability i

46 The microchip was used for separation of bioactive peptides and amino acids labeled with a fluoro

47 tease, inactivates or degrades some of these bioactive peptides and chemokines, thereby regulating ce

48 These probiotics enhanced the generation of bioactive peptides and could possibly be commercially ap

49 etallopeptidase that metabolizes a number of bioactive peptides and degrades peptides released by the

50 ino acids retain the binding capabilities of bioactive peptides and display excellent signal-to-backg

51 e P (SP) belongs to the tachykinin family of bioactive peptides and exerts its many biological effect

52 Meprin substrates include bioactive peptides and extracellular matrix proteins.

53 ize a wide range of inorganic materials with bioactive peptides and have the potential to be used in

54 ny additional peptides, including additional bioactive peptides and proline rich peptides (PRPs).

55 The oral delivery of bioactive peptides and proteins is prevented by the inte

56 The work herein was carried out to identify bioactive peptides and proteins that are susceptible to

57 the specific health benefits associated with bioactive peptides and the reduction of protein allergen

58 the specific health benefits associated with bioactive peptides and the reduction of protein allergen

59 ion of sparse networks where nodes represent bioactive peptides, and edges between two nodes denote t

60 d anticancer activities, lipid peroxidation, bioactive peptides, and microstructure of the beverages

61 rifugation and analyzed for protein content, bioactive peptides, and minerals.

62 ical opioid prohormones can generate several bioactive peptides, and these divergent families of proh

63 om a physiological point of view is that the bioactive peptides, angiotensins I and II and vasoactive

64 ein content with good amino acid balance and bioactive peptides (antioxidant, antihypertensive, immun

65 d 3) prevention of the inactivation of other bioactive peptides apart from GLP-1, such as glucose-dep

66 alpha-MSH and other bioactive peptides are cleavage products of pro-opiomela

67 ia californica as the model, a wide range of bioactive peptides are detected within each vesicle.

68 Several bioactive peptides are encrypted within the sequence of

69 The cleaved bioactive peptides are known to possess activities that

70 Bioactive peptides are oligopeptides that consist of 2-2

71 Bioactive peptides are packaged in large dense-core secr

72 Bioactive peptides are polypeptides with specific amino

73 es in these mice showed a decrease in mature bioactive peptides as a result of a decrease in both car

74 133 on the production of soybean flours with bioactive peptides as modulators of oxidative stress and

75 ulate physico- and biochemical properties of bioactive peptides as well as chiral inducers in asymmet

76 l protein maturation and release of specific bioactive peptides at the right place and right time rem

77 Numerous low molecular mass bioactive peptides (BAPs) can be generated during the hy

78 Bioactive peptides (BAPs) from milk proteins hold promis

79 Bioactive peptides (BAPs) represent a unique class of pe

80 We designed a series of bioactive peptides based on deep analysis of VEGFR2-bind

81 elation to heat-damage and occurrence of the bioactive peptides beta-casomorphins (BCMs).

82 model architecture for transfer learning in bioactive peptide binary classification modeling.

83 g affinity or specificity, thereby improving bioactive peptides' bioavailability.

84 or health benefits, with immune proteins and bioactive peptides (BPs) contributing to these benefits.

85 drolysis can facilitate the release of novel bioactive peptides (BPs) with unique biological activiti

86 Disulfide bonds stabilize many bioactive peptides, but their susceptibility to reductio

87 trate, it will have multifactorial uses as a bioactive peptide by itself or in tissue engineering.

88 Feather waste was valorised into bioactive peptides by extracting high-purity L-Cys-urea

89 peptidase that yields endothelin-3, a potent bioactive peptide, by cleavage of big endothelin-3, a la

90 d in the biosynthesis of the broad family of bioactive peptides called ribosomally synthesized and po

91 ed before the therapeutic potential of these bioactive peptides can be established.

92 ty to rapidly filter sequences for potential bioactive peptides can greatly compress the time between

93 Bioactive peptides can provide health benefits due to di

94 However, an analysis of over 1000 bioactive peptide candidates suggests that many have und

95 Nonribosomally and ribosomally synthesized bioactive peptides constitute a source of molecules of g

96 actic acid bacteria fermentation can enhance bioactive peptide content in vegetables.

97 In the current context of food safety, bioactive peptides could be of interest as preservatives

98 e present study was to determine whether the bioactive peptides could have been amelogenin protein de

99 Bioactive peptides DDSPDLPK, EMPFPK and TPEVDKEALEK were

100 Bioactive peptides derived from food proteins have impor

101 searched the literature for all instances of bioactive peptides derived from milk proteins from any m

102 ate independently the secretion of different bioactive peptides derived from the same gene product.

103 is study provides support for the concept of bioactive peptide design based on protein surface epitop

104 e development of the PepSAVI-MS pipeline for bioactive peptide discovery.

105 Bioactive peptides displayed anti-inflammatory, immunomo

106 is showed the production of multi-functional bioactive peptides due to the hydrolysis of whey protein

107 nd to investigate their capacity to generate bioactive peptides during milk fermentation.

108 well as the loss in functional properties of bioactive peptides during storage.

109 to the detection of greater numbers of known bioactive peptides (e.g., peptide hormones) during the a

110 ZmPep1 is a bioactive peptide encoded by a previously uncharacterize

111 from this study showed first time report on bioactive peptides, especially anti-inflammatory, from g

112 Bioactive peptide extracted at a hydrolysis condition of

113 carrier designed to prolong the presence of bioactive peptides following intraarticular delivery.

114 a demonstrate that CEMP-1-p1 is an effective bioactive peptide for bone tissue regeneration.

115 otential dual imaging probes consisting of a bioactive peptide for tumor targeting, a biocompatible d

116 kaline solution can be a potential source of bioactive peptides for addition to foods.

117 f random peptide libraries has yielded novel bioactive peptides for cell surface receptors.

118 It should be possible to identify novel bioactive peptides for orphan GPCRs by the combination o

119 ent observation of the very high affinity of bioactive peptides for oxidized fatty acids and phosphol

120 sts with other tumor systems, where multiple bioactive peptide fractions have been detected.

121 source of high quality proteins with various bioactive peptide fractions.

122 Bioactive peptides frequently terminate with an essentia

123 assembly of the C-36 peptide, a circulating bioactive peptide from the alpha1-antitrypsin serine pro

124 novel cyclic peptide that comprises a small bioactive peptide from the annexin A1 protein grafted in

125 rough the successful identification of known bioactive peptides from a botanical species, Viola odora

126 Some bioactive peptides from beta-casein presented significan

127 The aims of the present study are to produce bioactive peptides from bovine and goat milk subjected t

128 nsive, energy-efficient production of potent bioactive peptides from caseins in milk at low temperatu

129 oteases responsible for the release of these bioactive peptides from CgA have not been established.

130 Bioactive peptides from fermented foods are gaining glob

131 hnology for the cost-effective production of bioactive peptides from lentil proteins during enzymatic

132 is by different proteases and the release of bioactive peptides from lentil proteins.

133 This study was aimed to produce bioactive peptides from optimally fermented tempe, and m

134 were considered for efficient production of bioactive peptides from RBP.

135 ection that can lead to efficient release of bioactive peptides from rice bran proteins for functiona

136 oduct can be processed to obtain calcium and bioactive peptides from the separated bones and meat res

137 -up process was carried out to obtain potent bioactive peptides from whey protein through a simple hy

138 significantly inhibited in roots expressing bioactive peptides fused to the maize cytokinin oxidase/

139 The bioactive peptides galanin, spexin and kisspeptin have a

140 milk proteins are an important substrate for bioactive peptides generation.

141 fibroblast cell migration behavior across a bioactive peptide gradient illustrates preservation of p

142 xible technique for the covalent addition of bioactive peptide gradients to a surface or gel and a si

143 es validated the sequences of the synthetic, bioactive peptides HA and BMP2, which contained highly b

144 g technologies, the high efficacy of various bioactive peptides has been demonstrated in vitro, albei

145 iour in animals are neuropeptides, and a few bioactive peptides have already been identified in A. ja

146 nd future perspective of SAR of food-derived bioactive peptides have been addressed.

147 Bioactive peptides have been identified in lactic acid b

148 0 toxins from an estimated number of >70,000 bioactive peptides have been identified in the genus Con

149 gy in solid-phase peptide synthesis, several bioactive peptides have been prepared including cyclic,

150 Bioactive peptides have evolved to optimally fulfill spe

151 Among them, bioactive peptides have garnered huge scientific interes

152 Bioactive peptides have multiple conformations in soluti

153 ble for the processing of CgA and release of bioactive peptides have not been established.

154 Bioactive peptides have recently gained more research at

155 Food-borne bioactive peptides have shown considerable potencies as

156 r representing a chemical reference space of bioactive peptides, having an implicit knowledge that is

157 suggesting that it could yield more than one bioactive peptide; however, no in vivo activity has been

158 materials can be utilized as a scaffold for bioactive peptides; however, it may be advantageous to d

159 ondria (Mt) and the Mt-genome-encoded, small bioactive peptide humanin (HN).

160 p hypertension model, and to bioprospect for bioactive peptides identified by proteomic methodologies

161 ccurrence of direct interaction between milk bioactive peptides, Ile-Asn-Tyr-Trp, Leu-Asp-Gln-Trp, an

162 so may contribute to an understanding of the bioactive peptides important in chondrocyte signaling.

163 es, and mammals illustrate the importance of bioactive peptides in controlling numerous complex behav

164 This is the first report of tyrosine-rich bioactive peptides in Conus venom.

165 rent works have demonstrated the presence of bioactive peptides in different soybean-based foodstuffs

166 The generation of bioactive peptides in different types of dry-cured ham p

167 s spectrometry (MS) was employed to identify bioactive peptides in fermented cucumber.

168 pplied for expression and secretion of small bioactive peptides in mammalian cells.

169 nsible for processing the precursors of many bioactive peptides in mammals.

170 Clear evidence is shown of the presence of bioactive peptides in the jejunum of healthy humans who

171 egies to generate competitive antagonists of bioactive peptides include several possible structural m

172 POMC) is a precursor polypeptide for various bioactive peptides, including adrenocorticotropic hormon

173 successfully applied to a growing number of bioactive peptides, including alpha-, mu-, and omega-con

174 ase activity and degraded a variety of small bioactive peptides, including bradykinin, neurotensin, a

175 nc metallopeptidase that metabolizes several bioactive peptides, including insulin and the amyloid be

176 Insulin-degrading enzyme (IDE) hydrolyzes bioactive peptides, including insulin, amylin, and the a

177 Cone snail venoms contain a wide variety of bioactive peptides, including insulin-like molecules wit

178 a cell surface endopeptidase that hydrolyses bioactive peptides, including the bombesin-like peptides

179 PK2 is a bioactive peptide initially discovered as a regulator of

180 Injection of the bioactive peptides into slugs triggered defensive behavi

181 These cells are likely to secrete the bioactive peptides into the intestinal lumen in response

182 addition of the coupling agent gradient, the bioactive peptide is added.

183 A new study shows that a conserved bioactive peptide is released from its cytoplasmic precu

184 An in vitro system for the preparation of bioactive peptides is described.

185 tion to the classical cleavages, a subset of bioactive peptides is generated by processing at "noncla

186 In contrast, a subset of bioactive peptides is generated by processing at non-cla

187 Search for bioactive peptides is intensifying because of the risks

188 However, the clinical usefulness of such bioactive peptides is limited because they are rapidly d

189 o the structure-function properties of small bioactive peptides is of great importance.

190 protein essential to the production of many bioactive peptides, is cleaved and enters the regulated

191 port on the anti-cancer potential of a novel bioactive peptide isolated from Momordica charantia in v

192 A large number of bioactive peptides isolated from natural sources are kno

193 onus venom contains hundreds to thousands of bioactive peptides known as conotoxins.

194 Among them, bioactive peptides LA3IK and RP-7 induced pronounced tra

195 on, M13 phages with genetically incorporated bioactive peptide ligands direct both soft and hard tiss

196 ith particular attention paid to identifying bioactive peptide ligands generated by post-translationa

197 Macrocyclization can improve bioactive peptide ligands through preorganization of mol

198 Bioactive peptide LL-37/hCAP18, the only human member of

199 The application of this bioactive peptide may lead to implementing new strategie

200 s used to measure the specific uptake of the bioactive peptide melittin into N-isopropylacrylamide (N

201 h-added-value compounds, including proteins, bioactive peptides, minerals, heavy metals, and total an

202 344SQ encapsulated in bioactive peptide-modified, matrix metalloproteinase-deg

203 ase both intact Mt and humanin (HN), a small bioactive peptide normally transcribed from the Mt genom

204 zyme (ACE) regulates the levels of disparate bioactive peptides, notably converting angiotensin-I to

205 Bioactive peptides obtained from food proteins can be em

206 llent structural framework for deposition of bioactive peptides of the ECM, and their intrinsic bioph

207 Endogenous bioactive peptides, often called "neuropeptides," compri

208 Among the milk-derived bioactive peptides, only minor amounts of mono-phosphory

209 in 22 metabolites, including phospholipids, bioactive peptides, organic acids, and nucleotides.

210 , confers resistance to polymyxin B and to a bioactive peptide (P2) derived from the human bactericid

211 for G protein-coupled receptors sensitive to bioactive peptides (peptide GPCRs).

212 Because these bioactive peptides play a role in the inflammatory respo

213 Evidence suggests that these bioactive peptides play a role in the regulation of meta

214 Evidence suggests that these bioactive peptides play a role in the regulation of meta

215 enzymes to convert inactive precursors into bioactive peptides plus several cytosolic proteins to go

216 ented shrimp pastes are potential sources of bioactive peptides possessing ACE inhibitory and antioxi

217 s encoding potential ligands and describe 22 bioactive peptide precursors.

218 composition, interactions, and properties of bioactive peptides present in different food matrices.

219 Based on results in the present study, milk bioactive peptides presenting broad antimicrobial action

220 toglobulin or caseins, intensely studied for bioactive peptide production, relatively little attentio

221 derutilized resource with high potential for bioactive peptide production.

222 to the beta-lactone warhead, generating the bioactive peptide products.

223 that amyloids undergo transformation to the bioactive peptide/protein forms under specific condition

224 D7 isoform was produced and processed into a bioactive peptide referred to as nonadecaneuropeptide (N

225 d as a useful behavior for understanding how bioactive peptides regulate CNS function.

226 To review this large dataset, the bioactive peptides reported in the literature were visua

227 The production and regulated secretion of bioactive peptides require a series of lumenal enzymes t

228 Many bioactive peptides require amidation of their carboxy te

229 to explore the limits of affinity, with the bioactive peptide RGD as a model ligand.

230 Bioactive peptides (RQRK and VIK) were generated.

231 Bioactive peptide separated by gel-filtration chromatogr

232 a concise yet extensive survey of key short bioactive peptide sequences for a range of applications

233 ts depending on the protease used to release bioactive peptide sequences.

234 gastrointestinal tract and may contain novel bioactive peptide sequences.

235 ide a useful tool for cellular dissection of bioactive peptide signaling in a variety of organisms an

236 o pursue a comprehensive genetic analysis of bioactive peptide signaling, we have scanned the recentl

237 normal human lung and which hydrolyzes small bioactive peptides, some of which act as growth factors

238 using 125I-labeled GLP-1 confirmed that all bioactive peptides specifically displaced tracer with hi

239 ecialization of this neuropeptidase to small bioactive peptide substrates without bulky secondary and

240 e (IDE) is involved in the clearance of many bioactive peptide substrates, including insulin and amyl

241 is a protease that cleaves insulin and other bioactive peptides such as amyloid-beta.

242 , alongside more frequent detection of other bioactive peptides such as anabaenopeptins and cyanopept

243 biquitously participate in the catabolism of bioactive peptides such as neurotensin and bradykinin.

244 ansglutaminase-catalyzed covalent binding of bioactive peptides targeted to mineralized collagenous d

245 mass spectrometry and statistics to identify bioactive peptide targets from complex biological sample

246 A bioactive peptide that combines glucagon with the thyroi

247 yl tail, a beta-sheet forming peptide, and a bioactive peptide that is displayed on the surface of th

248 from other Conus species for similar, short bioactive peptides that allosterically modulate ligand-g

249 ed as the source of beta-casomorphins (BCMs) bioactive peptides that are implicated with various phys

250 that the crosslinked emulsion is a source of bioactive peptides that are liberated by human digestive

251 connective tissue protein extracts produces bioactive peptides that are non-cytotoxic, should be sta

252 (GLP-1) and several other naturally produced bioactive peptides that contain preferentially a proline

253 oadrenal system, are processed by plasmin to bioactive peptides that feed back to inhibit secretagogu

254 red ham constitutes a good source of natural bioactive peptides that have potential benefit for human

255 Enzymatic hydrolysis of proteins produces bioactive peptides that have the potential to provide he

256 r (EGFR) mediates the actions of a family of bioactive peptides that include epidermal growth factor

257 serves as a prohormone that is cleaved into bioactive peptides that inhibit catecholamine release, p

258 a novel platform for display and delivery of bioactive peptides that links the biological properties

259 es specialize in the hydrolysis of the small bioactive peptides that play a variety of signaling role

260 and neuropeptides encompass a large class of bioactive peptides that regulate physiological processes

261 tonin (sCT) is an example of one of the many bioactive peptides that require amidation of the carboxy

262 P12 belongs to a new class of bioactive peptides that they have named epiviosamines.

263 putative roles and targets to host factors (bioactive peptides) that control gene expression in the

264 catalyzes the carboxyl-terminal amidation of bioactive peptides through a two-step reaction involving

265 e importance of disulfide bridges in a small bioactive peptide to bring together frustrated structure

266 ynamic protein-protease system that delivers bioactive peptides to infants.

267 peptidase neurolysin (Nln) processes diverse bioactive peptides to regulate signaling in the mammalia

268 poly(ethylene glycol), or PEG, modified with bioactive peptides to study murine models of lung adenoc

269 at consumption of whey proteins will deliver bioactive peptides to target cells.

270 Despite several similarities, bioactive peptides unique to individual milk were identi

271 The construction of bioactive peptides using beta-amino acid-containing sequ

272 Production of bioactive peptides via enzymatic hydrolysis is a sustain

273 The bioactive peptide was identified as a nonmutated nonamer

274 Antioxidative bioactive peptide was successfully identified from pearl

275 The best preparative method for producing bioactive peptides was through papain hydrolysis and fol

276 The bioactive peptides, well-known to be in atrial gland ves

277 Putative matches of known food-derived bioactive peptides were identified by direct analysis us

278 41 potentially bioactive peptides were identified.

279 Antioxidative and antihypertensive bioactive peptides were successfully derived from Parkia

280 Bioactive peptides were successfully generated from prot

281 These novel bioactive peptides were suggested to be beneficial to nu

282 facilitate the identification of the minimal bioactive peptide, which would represent a more synthesi

283 tegies represent an approach for stabilizing bioactive peptides while keeping their full potencies an

284 Lunasin is a 5-kDa soybean bioactive peptide with demonstrated anti-cancer and anti

285 rocesses big ET-3, generating ET-3, a potent bioactive peptide with multiple biological roles.

286 actic acid bacteria (LAB) and yeasts produce bioactive peptides with a positive effect on human healt

287 In this technique, bioactive peptides with a terminal cysteine are bound vi

288 In conclusion, bioactive peptides with distinctive properties could pot

289 o our knowledge, this is the first time that bioactive peptides with glucose uptake activity have bee

290 and gelling, along with potential to produce bioactive peptides with health-promoting benefits.

291 a model system for studying interactions of bioactive peptides with membranes.

292 is of the fish bycatch allows the release of bioactive peptides with potential use in the food indust

293 e anti-biofilm surfaces were developed using bioactive peptides with proved activity to antibiotic re

294 s currently being applied to other important bioactive peptides with short half-lives.

295 onic side chains can be employed to generate bioactive peptides with significant systemic stability.

296 extracellular deposits represents a site of bioactive peptides with the ability to provide inappropr

297 probe for investigating the interactions of bioactive peptides with their receptors.

298 The increasing interest in bioactive peptides with therapeutic potentials has been

299 t important precursor of peptides, including bioactive peptides with various activities.

300 Two potential bioactive peptides, Xen-dorphin-1A and -1B, that were ch