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1 fic and regulatory approaches for evaluating bioactivity.
2 the gut microbiota, and preserve polyphenol bioactivity.
3 ive correlation between thiol reactivity and bioactivity.
4 red therapeutic targets for inhibiting their bioactivity.
5 liver, regulates leptin bioavailability and bioactivity.
6 methoxylation of PCBs resulted in diminished bioactivity.
7 performed to investigate their influence on bioactivity.
8 vesting year on elderberries composition and bioactivity.
9 uctural element could explain their specific bioactivity.
10 snail venom with moderate human insulin-like bioactivity.
11 tibody could be modified without diminishing bioactivity.
12 fluids, which significantly influences their bioactivity.
13 CW-covered mammalian cells can maintain high bioactivity.
14 a glycosylated phenol, displayed significant bioactivity.
15 garding the structural features required for bioactivity.
16 polymer bioconjugate structures with tunable bioactivity.
17 synthetic compound, demonstrate that it has bioactivity.
18 rgets provide an overall picture of chemical bioactivity.
19 ics of the beer, particularly its beneficial bioactivity.
20 causing consumer misinformation about their bioactivity.
21 h on the impact of processing on BRB product bioactivity.
22 hat the released drugs were able to maintain bioactivity.
23 ification is important for its proangiogenic bioactivity.
24 quisite printability, cytocompatibility, and bioactivity.
25 vo models suitable for studying export of NO bioactivity.
26 old, but the secreted insulin had diminished bioactivity.
27 fractory to S-nitrosylation, negated SNO-CoA bioactivity.
28 ology, including cargo sorting, release, and bioactivity.
29 r alternative uses of end-products with high bioactivity.
30 luence of a fourth disulfide bond on insulin bioactivity.
31 ibodies of defined composition with retained bioactivity.
32 eight pectin with high efficiency and higher bioactivity.
33 ecule drugs and RNA ligands without reported bioactivity.
34 designing fortified products with desirable bioactivity.
35 cophoric requirement for the antileishmanial bioactivity.
36 tification and analysis to the assessment of bioactivity.
37 suggesting that total IGF levels may reflect bioactivity.
38 black cumin seed oil (BCSO) and shows strong bioactivity.
39 ition) were used for screening of peppermint bioactivity.
40 with RNA interference resulted in a loss of bioactivity.
41 differences in peptide profiles and peptide bioactivities.
42 red to investigate the phenolic profiles and bioactivities.
43 prouts with health-promoting metabolites and bioactivities.
44 n and aloe-emodin of Rhubarb to increase the bioactivities.
45 nes), and most of them had multiple reported bioactivities.
46 mally fermented tempe, and map their overall bioactivities.
47 e compared with observed endocrine/mutagenic bioactivities.
48 t group of compounds that exhibit a range of bioactivities.
49 ause unexpected cell behaviors and regulated bioactivities.
50 he synthesis of TA derivatives with enhanced bioactivities.
51 on and considering their previously reported bioactivities.
52 cy of tested sesquiterpenoids supports other bioactivities.
53 eneration of peptides, soluble phenolics and bioactivities.
54 defined patterns of acetylation and specific bioactivities.
55 the phenolic compounds profile and in vitro bioactivities.
56 g system, which display a range of different bioactivities.
57 to have antibacterial, antifungal, and other bioactivities.
58 acterized for their chemical composition and bioactivities.
59 ociated with really promising properties and bioactivities.
60 age existing pharmacological data to predict bioactivity across a comprehensive molecular database of
61 ivity in chlorinated samples, an increase of bioactivity after complete removal of CFC was observed (
65 Lys, Gly and Leu, and also exhibited diverse bioactivities, among them primarily inhibition of dipept
66 n growth inhibition to characterize compound bioactivity-an approach that cannot be used to assess th
67 e databases, will hinder future discovery of bioactivities and affect the establishment of future die
68 he potential of precise assessment of ligand bioactivities and determination of key substructural fea
71 aimed to 1) investigate the characteristics, bioactivities and rheological properties of the exopolys
73 ents with the highest contribution to tested bioactivities and to highlight the most potent genotypes
74 method, SED, was proposed to predict ligand bioactivities and to recognize key substructures associa
75 rocess of saponin-rich extracts enhances the bioactivity and allows developing multibioactive product
76 ta-sheet of teixobactin is important for its bioactivity and an antiparallel dimer of teixobactin is
77 y modification that contributes to determine bioactivity and bioavailability of plant natural product
78 properties of a drug, both through presented bioactivity and by drug-like function of assemblies inte
79 learning can be used to predict AR-mediated bioactivity and can also be applied to other targets of
80 s that can be engineered to achieve enhanced bioactivity and describe current strategies being used t
81 isiae is a popular technique to preserve the bioactivity and increase the stability of functional bio
82 ts, especially for in vitro interrogation of bioactivity and mechanisms of action; rigorous assessmen
85 ulting TRAIL-Trimer not only retains similar bioactivity and receptor binding kinetics as native TRAI
86 e the relationship among chemical structure, bioactivity and temperature of chamomile during subcriti
88 methylcellulose films were characterized for bioactivity and the physicochemical analysis were carrie
90 diverse families of biomolecules with potent bioactivities, and they have important immunoregulatory
92 ior, outstanding mechanical properties, high bioactivity, and switchable chemical reactivity for func
93 display remarkable structural diversity and bioactivity, and therefore the biosynthesis and engineer
95 ive approach to substantially increasing the bioactivity annotation density both on the local and glo
96 rate prediction and interpretation of ligand bioactivities are essential for virtual screening and dr
98 extraction protocols, stability, safety and bioactivity are necessary to provide novel and promising
100 Polymer length and functionality affects bioactivity as long, charged polymers display higher muc
101 R analysis and are associated with decreased bioactivity as reflected by reduced drug-induced cellula
106 sequencing and gene deletion studies, while bioactivity assays showed antimicrobial activity against
107 physical, MS and both cell- and animal-based-bioactivity assays to characterize tau in 32 patients wi
109 timicrobials through large-scale isolations, bioactivity assays, genomics, metabolomics, and in vivo
111 tionwide survey of United States streams for bioactivities associated with 69 different end points us
112 dentification of simpler congeners retaining bioactivity at a much earlier stage of a synthetic effor
114 cond generation meroterpenoids with valuable bioactivities based on combinatorial biosynthetic strate
115 ting strategies, including structure- and/or bioactivity-based approaches, afford no information abou
116 ntial component of environmental monitoring, bioactivity-based assessments using in vitro systems inc
117 is known about the potential hazards (e.g., bioactivity, bioaccumulation, and toxicity) of most PFAS
119 herapeutic candidates with disease-modifying bioactivity, but their variable potency has complicated
120 ly have the fascinating ability to export NO bioactivity, but this occurs independently of SNO format
121 be essential for export of nitric oxide (NO) bioactivity by the red blood cell (RBC) to mediate hypox
123 est that caramel with butterscotch aroma and bioactivity can be produced with GlcN-amino acid at 70 d
126 reviously that monomeric GH-C53S has reduced bioactivity compared with WT GH (GH-WT) because of its d
128 altodextrin (1:9)-100 degrees C had the best bioactivity conservation after in vitro gastrointestinal
130 on strategies typically rely on experimental bioactivity data to determine the potency and selectivit
132 equently used libraries and toolkits for VS, bioactivity databases and gold-standard data sets for sy
133 prediction of small molecule properties and bioactivities depend on the critical choice of molecular
134 isted continuous evolution (PACE) to achieve bioactivity-dependent adaptation of the BGC for the anti
135 study demonstrates that features of natural bioactivity-dependent evolution can be engineered to acc
136 d extract in phenolic compounds and the main bioactivities described for these secondary metabolites,
138 ial as natural bee medicines, we developed a bioactivity-directed fractionation assay for nectar meta
141 ural products such as macrolides with potent bioactivities (e.g. antibiotics) and useful drug-like ch
142 stream of the WWTP and analyzed for in vitro bioactivities (e.g., agonism of ER, GR, and PPARgamma) a
143 es excellent performance in modelling ligand bioactivities, especially for those in the GPCR datasets
145 No relation was observed between the tested bioactivities except from the case that aglycone compoun
147 al blood mononuclear and T cells, along with bioactivity, flow cytometry, and isothermal titration ca
151 content of proanthocyanidins and with higher bioactivity from extraction residue than alkaline and ac
152 bioconjugation strategies that do not affect bioactivity, generate homogenous products, and can be pr
155 ard protocols for chemical fractionation and bioactivity-guided chemical analysis were used to identi
162 tests, MTT reduction cytotoxicity, HOS cell bioactivity (human osteosarcoma) by alkaline phosphatase
163 ase inhibitor to facilitate export of RBC NO bioactivity improved cardiac recovery after ischemia/rep
165 entification of metabolites with anti-cancer bioactivities in plants with no known medicinal pedigree
166 of broadly neutralizing distinct viper venom bioactivities in vitro by inhibiting different enzymatic
167 rm a search for P2RY8 ligands and find P2RY8 bioactivity in bile and in culture supernatants of sever
170 oval of AZI was in line with the decrease of bioactivity in chlorinated samples, an increase of bioac
172 d robustly establish the full spectrum of NO bioactivity in plants, it will be essential to apply met
174 nalytical framework for estimating molecular bioactivity in silico and complements conventional empir
175 here that current leads are limited by poor bioactivity in wheat, a widely grown staple crop, and in
176 arly 14,000 existing macrolactones and their bioactivity information from different public databases,
177 rst PFAS-specific database that contains the bioactivity information on 1012 PFASs for 26 bioassays.
180 protect cargo GF and maintain its long-term bioactivity, it is speculated that Coa-mediated delivery
181 and lengths, some of them exerting relevant bioactivities like angiotensin converting enzyme inhibit
182 of NO metabolism (NOx) also have significant bioactivity, little is known about the role of NO and NO
183 r after exposure for proteomics analysis and bioactivity measurements in rat aortic endothelial cells
185 relevance of NPs, yet exhibit structures and bioactivities not accessible to nature or through the us
188 rates the anti-angiogenic and pro-autophagic bioactivities of decorin as the molecular basis for tumo
190 ive samplers may be useful in evaluating the bioactivities of mixtures that people contact on a daily
191 sed an in silico approach for predicting the bioactivities of peptides generated by E. faecalis.
192 function and can account for the promiscuous bioactivities of phytochemicals, despite their limited b
195 pheles and Culex mosquitoes, we examined the bioactivities of the identified antagonists against Aede
197 below 1000 mg l(-1) partially stimulate the bioactivity of A. niger, which was confirmed by its elev
199 onal changes of polyphenolic composition and bioactivity of cardoon bracts of variable maturity.
201 study to investigate the thyroid disrupting bioactivity of chemical mixtures isolated from personal
204 escribe a hydrogel system for harnessing the bioactivity of embedded microbes for on-demand small mol
205 ed not to be crucial for the antileishmanial bioactivity of endoperoxides, under the tested condition
207 We compared the protein cargo and signaling bioactivity of exosomes released by hiPSC-derived neural
213 mplex coacervates significantly improved the bioactivity of IL-12 and provided protection from proteo
215 we provide an account of the composition and bioactivity of individual OPCs and more generally highli
216 new and advanced methodologies to study the bioactivity of isolated unknown TPs to understand their
219 ile replicating the complex architecture and bioactivity of native bone, compromising application of
222 rocess is able to affect the composition and bioactivity of oligosaccharides contained in the grape s
224 growth factors requires preservation of the bioactivity of printed growth factors, spatial localizat
226 ared the quantity, quality, and IgE-blocking bioactivity of SLIT-induced Mal d 1-specific IgG antibod
227 finding highlights the possibility that the bioactivity of such CECs may be effectively preserved th
228 ndings suggest that the strong pro-tenogenic bioactivity of tECM is regulated via integrin/TGF-beta s
229 rmore, P. gingivalis augmented secretion and bioactivity of TGFbeta through glycoprotein A repetition
230 imulated digestion on phenolic compounds and bioactivity of the African leafy green vegetable, Bidens
231 yet broader examinations of the identity and bioactivity of the entire circulating milieu remain unde
234 nor-NPD1, but not dinor-NPD1, maintained the bioactivity of the parent NPD1, inhibiting neutrophil ch
239 nary chemical reactivity studies imputed the bioactivity of these natural products to a DNA cross-lin
242 d to characterize the metabolite profile and bioactivity of two commercial bitter melon (Momordica ch
244 f 10 U kg(-1) insulin led to a dose-adjusted bioactivity of, respectively, 35%, 29% and 23% that of t
246 on by screening for Lasso of ECFPs and (iii) bioactivity prediction through a deep neural network reg
247 medical entity classification, compound-gene bioactivity prediction, and biomedical information retri
249 e bioengineered to increase their stability, bioactivity, presentation to acceptor cells and capacity
250 leaf extracts by PLE and SFE have remarkable bioactivity, presenting a great potential to be used as
252 ngineered IL-10 variant showed a more robust bioactivity profile than that of wild-type IL-10 at low
255 we collate emerging evidence showing that NO bioactivity regulates a growing number of diverse post-t
262 cancer and other diseases(1); however, their bioactivity requires gut bacterial conversion to enterol
263 up to six physicochemical properties and/or bioactivities, resulting in more than ten endpoints in t
264 of spectroscopic or spectrometric data with bioactivity results are known to improve dereplication i
265 AR models require in vitro data to assign a bioactivity score, Bayesian machine learning methods can
267 ive tool for visual analysis of the compound bioactivity space in the context of target proteins, dru
270 ucleotides, conducted their base pairing and bioactivity studies, and solved three new crystal struct
271 These metabolites displayed a wide range of bioactivities, such as teratogenic, cytotoxic, phytotoxi
272 ine and d-glucosamine units, possess diverse bioactivities that can be used for applications in, e.g.
275 gets lack experimental data about the ligand bioactivities; this is particularly true for G protein-c
277 PC and anti-pAkt) to cytosol to elicit their bioactivity towards binding intracellular protein epitop
279 their functional and thermal properties and bioactivity upon simulated gastro-intestinal digestion w
282 ted in the presence of nitrite, export of NO bioactivity was detected as inhibition of ADP-induced pl
284 xicity screening of the extracts showed that bioactivity was not linked to production of griseofulvin
287 hromatography and three distinct measures of bioactivity, we show that the predominant forms of Abeta
291 the WWTP replacement, ER, GR, and PPARgamma bioactivities were reduced by approximately 60-79%, no t
293 owed that thymoquinone concentration and its bioactivity were preserved better in PYC during storage
295 t of phage stability relies on plaque assay (bioactivity), which requires powder samples to be recons
296 ng and aggregation and resulted in prolonged bioactivity with a 10-fold increase in activity compared
297 using quartz crystal microbalance; and motor bioactivity with ATPase assay, on a set of model surface
298 of all examined varieties exhibited average bioactivity, with leaves of autochthonous variety Zuplja
300 ucts are rare and harbor various interesting bioactivities, yet the biochemical basis for the involve