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3 To mimic the 3D context of human arteries, bioartificial arteries were engineered from collagen typ
5 r advances will need to be made before these bioartificial devices can be considered for routine appl
6 stem-cell research, tissue engineering, and bioartificial devices for the treatment of the heterogen
7 n, multiagent immunosuppressant therapy, and bioartificial devices such as lacrimal gland microdevice
17 ne (PDMS), with which hypoxia in the core of bioartificial islets was alleviated and glucose-stimulat
20 l replacement therapy in a tissue-engineered bioartificial kidney comprising both biologic and synthe
23 herapeutic approach with a tissue-engineered bioartificial kidney may be a new treatment modality for
25 s, continuous renal replacement therapy, the bioartificial kidney, and peritoneal dialysis in the man
27 f chronic kidney disease, the development of bioartificial kidneys that mimic healthy kidney function
29 from lymphocytes of patients treated with a bioartificial liver (BAL) containing pig hepatocytes and
30 The purpose of this study was to develop a bioartificial liver (BAL) to treat patients with severe
35 art of an extracorporeal system, such as the bioartificial liver assist device, or an implantable tis
37 corporating the hepatocyte-like cells into a bioartificial liver device to treat fulminant hepatic fa
38 limitations of novel technologies including bioartificial liver devices and auxiliary liver transpla
43 ned, implemented and tested a clinical-scale BioArtificial Liver machine containing a biomass derived
45 heroids appear suitable for application in a bioartificial liver or as an in vitro liver tissue const
48 ck, neither of which is likely to respond to bioartificial liver support or treatment with convention
49 olved in a phase I/II clinical trial using a bioartificial liver support system (BLSS), we proceeded
51 atocyte cocultures, typically extracorporeal bioartificial liver support systems, are reviewed in the
52 ttempted by various approaches, for example, bioartificial liver support, extracorporeal pig liver pe
60 as drug screening, toxicological studies, or bioartificial livers are reliant on hepatocyte functiona
61 ause of the potential to use these cells for bioartificial livers, as a vehicle for gene transfer, an
66 esults support the application of engineered bioartificial matrices to promote vascularization for di
67 althy hematopoietic progenitor cells (HPCs), bioartificial matrixes from rat tail or purified human c
69 thod for delivery of rVEGF using implantable bioartificial muscle (BAM) tissues made from genetically
70 al applications in biocompatibility studies, bioartificial muscle engineering, skeletal muscle differ
71 e centimeter large, few hundred micron-thick bioartificial muscle tissues composed of viable, dense,
72 tal muscle cells were tissue engineered into bioartificial muscles and flown in perfusion bioreactors
73 tive to allotransplantation, patient-derived bioartificial myocardium could provide functional suppor
74 into biomaterials has engendered the use of bioartificial nerve conduits as an alternative to autolo
75 ing the rate and extent of regeneration, the bioartificial nerve graft holds great promise for improv
77 was achieved by introducing MuSCs into a 3D bioartificial niche comprised of a thin sheet of mouse m
80 ish the biosafety of this device and related bioartificial organ systems, these analyses support the
81 metabolic responses in several microfluidic bioartificial organs (liver, kidney, and cocultures), as
84 ionality and safety of the first stent-based bioartificial pancreas (BAP) device implanted endovascul
86 afe transplantation of porcine islets with a bioartificial pancreas device in diabetic primates witho
87 cell-derived insulin-producing cells (i.e., bioartificial pancreas devices) may achieve a functional
88 ic capacity of generic and user-programmable bioartificial pancreas devices, which accounts for highl
90 ntial of this novel hybrid model to create a bioartificial pancreas to treat type 1 diabetes is tanta
92 h a challenge in the case of generation of a bioartificial pancreas, we have combined fluorine magnet
94 such as oxygen supply, in the engineering of bioartificial pancreatic islets to ensure their viabilit
100 ring, we developed a mechanically responsive bioartificial tissue that responds to mechanical loading
101 e for the design and in vitro cultivation of bioartificial tissues, we have developed a multiscale co