ライフサイエンスコーパス: bioassay

1 thin-layer chromatography (HPTLC-UV/Vis/FLD-bioassay).

2 ted bednets was low (< 30% mortality in cone bioassays).

3 oxic rats were infused into an isolated lung bioassay.

4 dies and offers direct access to a practical bioassay.

5 soconstriction in an ex vivo rat aortic ring bioassay.

6 luorophore photobleaching in a solid surface bioassay.

7 ctivity of truncated TSLP using a PBMC-based bioassay.

8 the first time, a GMR-based time-domain MRX bioassay.

9 y to neutralize BoNT/H in the standard mouse bioassay.

10 to generate a same donor "vessel in a dish" bioassay.

11 es (<10 muL) and in just 5 min of on-the-fly bioassay.

12 ined by use of the H4IIE-luc transactivation bioassay.

13 es with biological activity in the zebrafish bioassay.

14 ous flow systems coupled with automation and bioassays.

15 for in vivo imaging and multiplexed in vitro bioassays.

16 owing to the different requirements of such bioassays.

17 imethoate were compared in active ingredient bioassays.

18 eveloped for high-throughput screening (HTS) bioassays.

19 estern Corn Belt by laboratory dose-response bioassays.

20 stently analyze the data produced by in vivo bioassays.

21 inked to relative potencies in pathway-based bioassays.

22 ug/cm(2) of Vip3Aa39 protein in diet-overlay bioassays.

23 e little or no cytotoxic activity in several bioassays.

24 f OSPW in mammals using a series of in vitro bioassays.

25 uman in vitro liver microsomal and cytosolic bioassays.

26 studied using conjugation and transformation bioassays.

27 c systems that incorporate these widely used bioassays.

28 for cytokinin activity in several cytokinin bioassays.

29 th Aliivibrio fischeri and Bacillus subtilis bioassays.

30 ts revolutionized the development of digital bioassays.

31 All were antagonists in bioassays.

32 pplicability to strategies for synthesis and bioassays.

33 significant improvements to high-throughput bioassays.

34 ptible population (SS) based on diet-overlay bioassays.

35 bioactivity information on 1012 PFASs for 26 bioassays.

36 at deal of promise for use in stable isotope bioassays.

37 ng fluorescence-based in-droplet single-cell bioassays(2), with sequencing of paired antibody V genes

38 to carcinogen testing adopts the 2-y rodent bioassay, a time-consuming and costly procedure.

39 he AF extract that partly contributed to the bioassay activity.

40 The developed bioassay allowed the determination of the potency and ef

41 finity membrane developed for biosensors and bioassays also in multiple use.

42 a critical adjustable parameter for certain bioassay analyses where magnetic nanoparticles are used

43 chromatographic fractionation and subsequent bioassay analysis revealed activity in fractions over a

44 Bioassay analysis using cell-based reporter gene assays

45 -mediated rolling circle amplification (RCA) bioassay and an (2) agarose bead-based microfluidic devi

46 proach of experimental testing in a relevant bioassay and analysis of the results by FSC.

47 med presumptive positives using direct mouse bioassay and culture.

48 K (PrP(res)), residual infectivity by mouse bioassay and in vitro templating activity by protein mis

49 gnancy microenvironment, we employed a mouse bioassay and RT-QuIC.

50 s was demonstrated in a biorelevant in vitro bioassay and the effectiveness of BTZ by pulmonary deliv

51 vels of resistance observed in dose-response bioassays and actual efficacy of formulated product need

52 Routine in vitro bioassays and animal toxicity studies of drug and enviro

53 d dLPG, in low RI region (1.333-1.347) where bioassays and biological events were usually carried out

54 applications are few despite advancements in bioassays and biosensor research.

55 tion binding assays, ex vivo rat aortic ring bioassays and BRET-based biosensor experiments.

56 We used behavioral observations, bioassays and chemical analysis to determine how males m

57 ADs enable simple, rapid, and cost-effective bioassays and environmental monitoring, which provide pr

58 microfluidic devices is vital for efficient bioassays and fabrication of complex microstructures.

59 s of undocumented purity that interfere with bioassays and have a low likelihood of becoming therapeu

60 tion analytics, which encompasses microarray bioassays and mass spectrometry (MS) of components from

61 d based on evidence from experimental animal bioassays and mechanistic studies.

62 gical and chemical signatures using in vitro bioassays and nontarget high-resolution mass spectrometr

63 The combination of our bioassays and the transcriptomic analysis indicate that

64 was assessed using three in vitro short-term bioassays and their migrations were carried out using a

65 Using disease bioassays and transcriptomic analysis we show that intac

66 using simulated sunlight, in both laboratory bioassays and trials on cabbage and tomato plants, that

67 targeted metabolomics with insect herbivore bioassays and with a set of growth-related traits of sev

68 -multi-imaging-bioassay, NP-HPTLC-UV/vis/FLD-bioassay) and the MS.

69 ecific feature, measurable by PMCA and mouse bioassay, and a great tool to distinguish prion strains.

70 Antibiotic exposure was ascertained by serum bioassay, and for cases, by a record of antibiotic treat

71 nalyses, short-duration in vivo and in vitro bioassays, and quantitative structure activity relations

72 in addition to their security and multiplex bioassay application.

73 ule for qPCR sensor development and relevant bioassay applications.

74 The new method was compared to a standard bioassay approach, and its applicability was demonstrate

75 In vitro bioassays are sensitive, effect-based tools used to quan

76 In vitro screening experiments (i.e. bioassays) are frequently used for this purpose; however

77 r 9000 compounds screened through up to 1100 bioassays, are now available.

78 formulation appears suitable for use in diet bioassays as a tool for evaluating the resistance of NCR

79 Incorporation of in vitro bioassays as complements to chemical analyses in standar

80 of the same hamster in a Y-tube olfactometer bioassay, at a late stage of infection.

81 ll-based in vitro and low-complexity in vivo bioassays based on algae, daphnids or fish embryos are a

82 For this purpose, different on-chip miRNA bioassays based on sandwich and competitive formats are

83 These results underscore the value of bioassay-based monitoring of environmental mixtures for

84 eveloping highly sensitive luminol-ECL-based bioassays, because the surfactant selection can be based

85 However, in preliminary field bioassays, beetles were not attracted by any known ceram

86 ant coffee were determined using DR CALUX(R) bioassay, before and after intestinal metabolization by

87 system compared to previous microwell-based bioassays but, with the detection limit of 180 fM, it is

88 toxicity of water samples can be tested with bioassays, but a metabolomic approach has the advantage

89 ulting fractions were dried and subsequently bioassayed by sequential printing of nL-volumes of reage

90 Using the optimized sandwich bioassay, calibration curves were made with series of IF

91 g predictive genotyping methods and targeted bioassays can focus toxicity assessments on ecologically

92 Quantitative bioassays capable of sensitive and specific determinatio

93 In both topical and fumigant bioassays, carvacrol and thymol were the most active com

94 h data, redesigned BioAssay record page, new BioAssay classification browser and new features in the

95 Several bioassay clusters showed high predictivity for acute ora

96 When dosing such extracts into in vitro bioassays, co-dosed lipids act as an additional phase th

97 and 0.08% decyl PEG, which is similar to the bioassay conditions for lipid II polymerization.

98 Functional bioassays confirmed that CD4(+) T cells from infected de

99 g and parametrizing the interactions between bioassay constituents.

100 Therefore, it is necessary to establish a bioassay correlating with the drug's known mechanism of

101 ic communities by deploying two standardized bioassays (cotton strips and two types of commercially a

102 e waters and indicating the need for broader bioassay coverage to assess potential adverse impacts.

103 nd five types of mixture effects in in vitro bioassays (cytotoxicity; activation of the estrogen, ary

104 ternatives to bisphenol A (BPA), but limited bioassay data are available on their estrogenic activity

105 In classical pharmacology, bioassay data are fit to general equations (e.g. the dos

106 ional method to automatically extract useful bioassay data from a public repository (i.e., PubChem) a

107 Bioassay data were correlated to MS data obtained using

108 Aside from its vector control potential, our bioassay data, in contrast to numerous other reports, pr

109 The in vitro bioassay data-driven profiling strategy developed in thi

110 n be wholly calibrated from standard chronic bioassay data.

111 e incompleteness, biasness, and noisiness of bioassay data.

112 tal data for ~ 2500 compounds in the PubChem bioassay database (AID: 1508591).

113 s work, we provide an update for the PubChem BioAssay database describing several recent development

114 PubChem's BioAssay database has served as a public repository for

115 ed in assay experiments are contained in the BioAssay database.

116 Nude mouse bioassay demonstrated better islet function for low-dose

117 odified somatropin to hGHBp; and (iv) a hGHR bioassay demonstrated initiation of the signal transduct

118 es to manage thrips in China, and laboratory bioassays demonstrated that F. occidentalis is significa

119 ns were compared to those determined using a bioassay-derived method (BDM) (i.e., an additivity-indep

120 ood have limited the utility of quantitative bioassays developed for the purpose.

121 Bioassay-driven purification of B. fragilis supernatant

122 t-effectiveness compared to existing digital bioassays, dSimoa increases amenability to integration i

123 ich is also an indication of the increase in bioassay efficiency.

124 Despite this, most Bt bioassays employ carbohydrate-biased rearing diets.

125 We modelled the 50% growth inhibition bioassay end-point (GI50) of 17,142 compounds screened a

126 nt genetic background, and complexity of the bioassay environment.

127 attempted copulation ( approximately 70%) in bioassays, equivalent to rates observed at orchid flower

128 , enabling broad applications of paper-based bioassays especially for point-of-care detection in reso

129 In three bioassay experiments, we tested the role of vertical soi

130 quilibrium partitioning model for cell-based bioassays extended by an additional lipid phase.

131 a sensitive, inexpensive, fast, and reliable bioassay for application in food analysis, forensic inve

132 ra, stool, and gastric aspirates using mouse bioassay for BoNT and/or culture for Clostridium botulin

133 paper we describe the development of a fast bioassay for determining IFX concentration in serum usin

134 ective is minutralization of the development bioassay for making on-desk device and specially merging

135 show the suitability of the newly developed bioassay for monitoring GPCR-mediated activity.

136 In this work, we developed a bioassay for oral delivery of dsRNA to an invasive fores

137 ate the development of a rapid and effective bioassay for oral delivery of dsRNA to screen additional

138 Using an adult beetle feeding bioassay for oral ingestion of dsRNA, we measured the ex

139 erall, this work provides a proof-of-concept bioassay for simple and portable molecular diagnostics o

140 When implementing the bioassay for the screening of plasma, a pronounced recep

141 mmobilization in DNA microarray and numerous bioassays for decades, whereas they are faced with limit

142 cine and also in the design of more relevant bioassays for drug discovery and development.

143 ) of the colorimetric and fluorescence based bioassays for GFAP was decreased by ~1000 times using th

144 as found to be inactive in vivo in microbial bioassays for methionine synthase and acted as an in vit

145 platform capable of high performance cardiac-bioassays for point-of-care applications.

146 ncongruens as compared to "single-substance" bioassays for similar species.

147 cheme of hydrogen peroxide related enzymatic bioassays for ultrasensitive detection of small molecule

148 Performing bioassay formats based on enzyme and antibody recognitio

149 Three bioassay formats have been developed, namely (a) a biolu

150 ility of freely choosing a wide diversity of bioassay formats, including those requiring long incubat

151 Using a novel subspace clustering algorithm, bioassay groups that may inform on relevant toxicity mec

152 These bioassays groups were used to predict animal acute oral

153 This study screened the bioassay guided isolation of BA from D. indica and explo

154 In a bioassay-guided approach using liquid chromatography and

155 Bioassay-guided chromatographic fractionation of 2 super

156 Bioassay-guided fractionation identified two oxazole nat

157 The bioassay-guided fractionation of the aril of Myristica f

158 Bioassay-guided fractionation of the source extract resu

159 ed 80% inhibition at 256 ug/mL and underwent bioassay-guided fractionation, leading to the isolation

160 For further bioassay-guided isolation of the main antimicrobial comp

161 tions as they have been determined either in bioassay-guided purification approaches or in bioassays

162 These results suggest that the FAST-DOSE bioassay has large potential as a useful diagnostic tool

163 Another sample track without bioassay has thus been handled in parallel.

164 This novel bioassay has usefulness in vascular biology research, pa

165 g oxidative activity, but imply conventional bioassays have a systematic bias toward Fe.

166 Low-cost, high-throughput in vitro bioassays have potential as alternatives to animal model

167 echniques that combine chemical analysis and bioassays have the potential to facilitate the identific

168 -nuclear magnetic resonance spectroscopy (HR-bioassay/HPLC-HRMS-SPE-NMR).

169 ng as an 'add-on' label for a broad range of bioassays improves their signal-to-noise ratio and dynam

170 Brain samples from selected pigs were also bioassayed in mice expressing porcine prion protein.

171 Control bioassays included the commercially available gold stand

172 ids may enable key hallmarks of tissue-based bioassays, including drug screening, tumor dissemination

173 Bioassays indicate that this structure is associated wit

174 Consistent with past studies, bioassays indicated that field populations were resistan

175 hromatography-mass spectrometry analyses and bioassays indicated that R. speratus worker release the

176 chemicals of different hydrophobicity in two bioassays, indicative of the aryl hydrocarbon receptor a

177 ork for the incorporation of next-generation bioassays into biomaterials design to effectively optimi

178 However, incorporating in vitro bioassays into chemical toxicity evaluations such as rea

179 By collecting, analyzing, and running bioassays involving mite-infested and control brood extr

180 the best area-under-the-curve score for each bioassay is 0.916.

181 ecosystem-level effects from single-species bioassays is a major challenge in environmental risk ass

182 ded the commercially available gold standard bioassay kits run at room temperature.

183 ms as compared to the commercially available bioassay kits.

184 th LC/MS, a low-cost antimicrobial detection bioassay lacked a sufficient negative predictive value (

185 uids, the main application potential of this bioassay lies in the characterization of these scarcely

186 Unwanted evaporation of bioassay liquids was circumvented by employing mineral o

187 This reduced the bioassay load and separated analyte signals thereof.

188 Here, the reduction of bioassay matrix signals was achieved by integrating a mi

189 udy of enzymatic reactions directly from the bioassay matrix with an effective analysis time of 0.3 s

190 Mediterranean Sea was measured using a mouse bioassay (MBA) and LC-MS-MS.

191 Plants were phenotyped in bioassays measuring parasitic wasp Cotesia sesamiae (Cam

192 lar compounds and split-off the salts of the bioassay medium in the first minutes.

193 gether with the bioactive zone, the adsorbed bioassay medium is eluted into the mass spectrometer (MS

194 ere investigated to reduce the impact of the bioassay medium load.

195 However, most bioassay medium mass signals were predominantly detectab

196 idin-biotin particles as a simple bead-based bioassay model.

197 goal of the experiment, material screens and bioassays must be arranged in specific ways.

198 In 7 day bioassays (n = 30), we examined ecotoxicological differe

199 ance thin-layer chromatography-multi-imaging-bioassay, NP-HPTLC-UV/vis/FLD-bioassay) and the MS.

200 th cell wall digesting enzymes, coupled with bioassay of guard cell function) plus modeling lead us t

201 onic biosensors for the competitive affinity bioassay of range-extended small molecules may thus be p

202 trated by a graphene field-effect transistor bioassay of small-molecule glucose as a proof-of-princip

203 he natural product could be assigned using a bioassay on (+)-1 and (-)-1.

204 itre and the integration of various types of bioassays on a single miniaturized platform.

205 y not feasible in the absence of appropriate bioassays or predictive markers for characterization of

206 Bioassays performed in first-instar larvae demonstrated

207 ediment in Flanders to results from toxicity bioassays performed on the ostracod Heterocypris incongr

208 It is a promising next-generation bioassay platform for early-stage disease diagnosis and

209 mes using the MAB technique and our circular bioassay platforms as compared to the commercially avail

210 e use of the MAB technique with the circular bioassay platforms for the rapid detection of GFAP in bu

211 In estuarine bioassays, predenitrification BNR effluents produced mor

212 on of blood plasma separation and multi-step bioassay procedures.

213 usefulness of performing counter-screens for bioassay promiscuity and assay interference, and raise c

214 ercomes high control mortality seen in other bioassay protocols and expands testing to include males

215 hance signals or are present, owing to given bioassay protocols, yet little is known regarding their

216 red with chromatographic fingerprinting, the bioassay provided better discrimination ability for some

217 ivity in orally inoculated pigs with a mouse bioassay raises the possibility that naturally exposed p

218 g added sources of research data, redesigned BioAssay record page, new BioAssay classification browse

219 dical research, and the vast majority of the bioassays rely on thermocycling that uses time-consuming

220 s assayed for mutagenicity in the Salmonella bioassay (reported here), 25% had low mutagenic activity

221 gical databases, pharmacology resources, and bioassay repositories.

222 However, bioassay responses were not in line with any of the calc

223 A quantitative lipid correction of bioassay results in the presence of co-dosed lipids was

224 Moreover, the bioassay results revealed that Rs-cps transgenic N. bent

225 Insect bioassay results showed 100% mortality of H. armigera wi

226 Insect bioassays revealed decreased virulence for two cyclophil

227 Insect bioassays revealed decreased virulence of the DeltaBbThm

228 Additionally, bioassays revealed resistance to eCry3.1Ab maize and cro

229 Insect bioassays revealed significantly reduced virulence of th

230 Our bioassays revealed that SA is necessary to restrict path

231 were successfully proven: NP-HPLC-UV/vis/FLD-bioassay-RP-HPLC-UV/vis-ESI(-)-MS with a valve switch an

232 S with a valve switch and NP-HPLC-UV/vis/FLD-bioassay-RP/IEX-HPLC-UV/vis-ESI(+/-)-MS with or without

233 ivo correlations (IVIVCs), the most relevant bioassay(s) related to hepatotoxicity were identified.

234 imeric 2'-OMe-pS/pO control, during in vitro bioassay screens designed to evaluate their potential as

235 Extracts dosed in the AREc32 bioassay showed a linear increase of apparent EC with in

236 Bioassays showed significant mortality of larvae fed on

237 Bioassays showed that bacteria in nonsterile larvae and

238 Synergist bioassays significantly recovered deltamethrin susceptib

239 Combining bioassays, spectroscopy, and wet-chemical analysis, we f

240 The bioassays suggest an impaired functionality of the signa

241 riants differed strikingly among the various bioassays, suggesting that the NCR peptide-based languag

242 (lettuce) bioassays supported by liquid chromatography-mass spectr

243 In field bioassays, synthetic trichoferone was more attractive to

244 Therefore, a simulated aerial application bioassay technique was developed to evaluate how the est

245 rug discovery and translation due to lack of bioassay technologies that can discriminate drug binding

246 ility was measured for protective effect and bioassay test was performed on the formulations of Bt.

247 Our study uses a novel multimetric bioassay that is able to disentangle the contribution by

248 d-phase extraction and dosed into cell-based bioassays that cover (i) cytotoxicity; (ii) activation o

249 Our results suggest that Bt resistance bioassays that use ecologically- and physiologically-mis

250 enabling high-resolution and high-throughput bioassays that, if incorporated into a biomaterial desig

251 Consequently testing in rodent bioassays, the current gold standard of toxicity testing

252 Two standardized toxicity bioassays, the immobilization of the invertebrate Daphni

253 PrP) mice may serve as a useful paradigm for bioassaying these prion isolates.

254 neous surface diffusion model to an in vitro bioassay to evaluate COX-1 inhibition.

255 nd extract from each wristband was used in a bioassay to quantify TRbeta antagonism in human embryoni

256 eliminate this interference, we developed a bioassay to remove nitrite in HS samples using the denit

257 multiple PCP-B mutant lines were utilized in bioassays to assess effects on pollen hydration, adhesio

258 Fluorescent labels are commonly used in bioassays to enhance sensitivity, but autoluminescence o

259 plementing chemical analysis with untargeted bioassays to help focus regulatory efforts on the most s

260 silicon photosensors, and chemiluminescence bioassays to provide highly sensitive analyte detection

261 robiome analysis with in vitro and in planta bioassays to show that competition for iron via secreted

262 able AHR-activating potencies in DR CALUX(R) bioassay (up to 79% of positive control activity).

263 f auxin on shoot cell expansion provided the bioassay used to isolate this central plant hormone near

264 Toxicity bioassays using artificial diet have proven to be valuab

265 for the DeltaBbpacC strain in topical insect bioassays using larvae from the greater waxmoth, Galleri

266 es including water, sediment, and biota into bioassays using total extraction or polymer-based passiv

267 re used as "on-the-fly" sensing platforms in bioassays, using a highly selective affinity peptide pro

268 The established point-of-care (POC) FO-SPR bioassay was also used to measure IFX in 100-fold dilute

269 n quality of red and green lentils, a rodent bioassay was conducted and compared to an in vitro metho

270 o-sensitive Pb(5)S(2)I(6) catalyst-based PEC bioassay was constructed for the detection of low-abunda

271 The established bioassay was finally validated using five IFX treated IB

272 The bioassay was positive in four out of five pigs assayed.

273 nthrin (a pyrethroid insecticide) in topical bioassays was 72,000 times higher than carvacrol, while

274 e original bioprofiling (NP-HPTLC-UV/vis/FLD-bioassay) was prolonged from 3 to 13 min per sample, suc

275 fication and cellular and animal infectivity bioassays), we studied the potential role of the molecul

276 Using a greenhouse bioassay, we explored how spatial heterogeneity of natur

277 Using Matrigel patterning as a bioassay, we provide the first functional demonstration

278 Through cell-based bioassay, we show that NSC80734 inhibits IL-18-induced p

279 In multiple-choice bioassays, we characterized the response of adult Drosop

280 In a series of ex vivo bioassays, we demonstrated that uterine PVAT had pro-con

281 ass spectrometry, structure elucidation, and bioassays, we found that the helper bacteria inactivate

282 Different parameters related to the bioassay were optimized, adhering the piece of paper ont

283 phytoplankton production, nutrient addition bioassays were conducted in the N-limited Neuse River Es

284 Bioassays were conducted in xeroderma pigmentosum group

285 Bioassays were conducted on mosquitoes, while breeding w

286 re analyzed for contaminants, and laboratory bioassays were performed with A. subtenuis.

287 Targeted bioassays were used to quantify the effects of UVB at mu

288 e, we report on the development of a 5-HT2AR bioassay, which monitors beta-arrestin2 recruitment to t

289 icidal activities was also evaluated in diet bioassay, which showed a single nucleotide mutation can

290 In a root growth bioassay with Arabidopside A isolated from fer mutants,

291 ntibody conjugate to obtain a sandwich-based bioassay with the capability to increase the SPR signal

292 To this end, 28 day life cycle bioassays with Chironomus riparius using intact whole se

293 t reveals new complexities arising in Hg(II) bioassays with cysteine and emphasizes the need for cons

294 We conducted laboratory bioassays with maize hybrids producing Bt toxins Cry3Bb1

295 ioassay-guided purification approaches or in bioassays with plants in which the expression of specifi

296 In vitro bioassays with purified compounds reveal selective growt

297 24 h mortality or >= 95% 60 min knockdown in bioassays with pyrethroid susceptible Anopheles farauti

298 In bioassays with Pyricularia oryzae, Gibberella fujikuroi,

299 in different pH conditions using behavioural bioassays with shore crabs (Carcinus maenas) as a model

300 Possible applications of the bioassay would lie in the characterization of serotonerg