ライフサイエンスコーパス: biochemical characterization

1 ntramembrane enzymes are often difficult for biochemical characterization.

2 accompanying structure-based mutagenesis and biochemical characterization.

3 tegral membrane protein, has defied standard biochemical characterization.

4 no vertebrate Pol zeta has been purified for biochemical characterization.

5 , stable protein required for structural and biochemical characterization.

6 hesis of camalexin was uncovered by in vitro biochemical characterization.

7 is often a prerequisite for biophysical and biochemical characterization.

8 as functionally confirmed by mutagenesis and biochemical characterization.

9 or over a century but has eluded genetic and biochemical characterization.

10 major difficulty in their overproduction and biochemical characterization.

11 rial uracil permease uraA allowed a detailed biochemical characterization.

12 cloned into an expression vector for further biochemical characterization.

13 activation, heterologous reconstitution, and biochemical characterization.

14 semirational design, random mutagenesis, and biochemical characterization.

15 nzyme Ube2T and describe its biophysical and biochemical characterization.

16 ork, we used Phanerochaete chrysosporium for biochemical characterization and analysis of catalytic s

17 Here we present biochemical characterization and crystal structures of a

18 Herein we report the biochemical characterization and crystal structures of t

19 Here we present the biochemical characterization and crystal structures of t

20 We have performed biochemical characterization and determined crystal stru

21 cable to other JmjC KDMs, facilitating their biochemical characterization and high-throughput screeni

22 Biochemical characterization and histological analysis s

23 In this study, we report the biochemical characterization and kinetic properties of h

24 We applied biophysical modeling, biochemical characterization and machine learning to dev

25 gh throughput mutagenesis screening studies, biochemical characterization and Rosetta-based structure

26 Here, we expand the biochemical characterization and understanding of TPP1 i

27 rexpression and purification, structural and biochemical characterization, and analysis of its expres

28 In this study, genetic analyses, biochemical characterizations, and physiological assays,

29 d submitting the mutant to physiological and biochemical characterization as well as to comprehensive

30 ltransferases are very diverse, making their biochemical characterization challenging.

31 A combination of in vitro biochemical characterizations, computational studies, en

32 Nevertheless, biochemical characterization confirms that TmMre11 posse

33 Glycan array and biochemical characterization data revealed PLL to be spe

34 These crystal structures and further biochemical characterization define a dodecapeptide of N

35 Biochemical characterization demonstrated that CYP71D12

36 Biochemical characterization established that the ERdj4

37 Biochemical characterization has revealed that each ACX

38 Biochemical characterization has shown that LepI can cat

39 Crystal structures and biochemical characterization have revealed that ECF tran

40 s, aided with high-resolution structures and biochemical characterizations, have provided a deeper un

41 This structural and biochemical characterization helps to rationalize the pr

42 Detailed biochemical characterization identified multiple active

43 Rigorous biochemical characterization identifies this second prot

44 Biochemical characterization in Arabidopsis thaliana rev

45 a complementary tool for real-time, in situ biochemical characterization in wound healing studies an

46 ding experiments using bzo1 mutants and BZO1 biochemical characterization indicated that the in vivo

47 Biochemical characterization indicates that this increas

48 Biochemical characterization indicates TtHGXPRT as a hom

49 complementation studies in combination with biochemical characterization, it was demonstrated that t

50 We present here the first in vitro biochemical characterization of 13 missense mutations in

51 ctions within GH74, here we coupled in-depth biochemical characterization of 17 recombinant proteins

52 of Moco pyranopterin backbone, we performed biochemical characterization of 3',8-cH2GTP and function

53 Here, we combined biochemical characterization of 39 DNTP derivatives with

54 We now report the first biochemical characterization of a bacterial vanadium-dep

55 Here, we report the functional and biochemical characterization of a c-di-GMP PDE, PdcA, 1

56 The first biochemical characterization of a chloroplastic disaggre

57 Here, we report the functional and biochemical characterization of a Drosophila ortholog of

58 In addition, we present the first in-depth biochemical characterization of a eukaryotic phycobilipr

59 This represents the first structural and biochemical characterization of a family 17 polysacchari

60 We further provide the first biochemical characterization of a flavoenzyme associated

61 Presented here is the structure and biochemical characterization of a GE, TtCE15A, from the

62 Biochemical characterization of a library of 13 oxygenat

63 This work represents the first biochemical characterization of a mannose-specific solut

64 We report the first biochemical characterization of a Moco-free eukaryotic N

65 Here we report the biochemical characterization of a multidomain deubiquiti

66 optimized chemical synthesis and preliminary biochemical characterization of a new oligonucleotide an

67 Here, we describe structural and biochemical characterization of a novel c-di-GMP effecto

68 We report the biochemical characterization of a novel NAL from a "GRAS

69 her, these findings demonstrate an extensive biochemical characterization of a novel series of highly

70 Here we describe the discovery and biochemical characterization of a selective small-molecu

71 s report, we describe the identification and biochemical characterization of a thiolase-ketoreductase

72 Here we describe the discovery and biochemical characterization of a unique glycosyltransfe

73 additional members of the AAD class, 2) the biochemical characterization of AAD-2 from Bradyrhizobiu

74 production of recombinant ALDH16, the first biochemical characterization of ALDH16, and the first cr

75 We undertook extensive biochemical characterization of Aldh7a1-KO mice consumin

76 Here, we have performed a molecular and biochemical characterization of an atovaquone-resistant

77 The biochemical characterization of an intact animal polyket

78 e report the biotechnological generation and biochemical characterization of an oligomer-specific ant

79 Here, we describe the structural and biochemical characterization of an oxygen-sensitive enzy

80 Here we report the resurrection and biochemical characterization of ancestral RuBisCOs, dati

81 iction factor, there has been no comparative biochemical characterization of APOBEC3H haplotypes.

82 en relative to venous blood, a comprehensive biochemical characterization of arteriovenous difference

83 Biochemical characterization of AtcpFHy/PyrP1 and AtPyrP

84 Biochemical characterization of B. subtilis RecD2 showed

85 Biochemical characterization of B5GLM7 reveals the major

86 Biochemical characterization of BER in the context of (C

87 This first biochemical characterization of Bim1 shows that it is no

88 Histologic and biochemical characterization of biopsied wound tissue, w

89 This study presents a biophysical and biochemical characterization of CA-SP and its assembly b

90 The corresponding biochemical characterization of CalS8 reveals CalS8 as o

91 However, the biochemical characterization of CBL-CIPK complexes has s

92 Here, we present additional biochemical characterization of CD1 and putative ortholo

93 Biochemical characterization of CENP-A associated RNAs r

94 Here, we report the genetic and biochemical characterization of chloroplast-located rubr

95 We present the first biochemical characterization of CNAbeta1, which is ubiqu

96 Biochemical characterization of CndF showed this enzyme

97 Our studies set the stage for the biochemical characterization of communesin biosynthesis.

98 dentifying tissue heterogeneity and detailed biochemical characterization of complex tissue samples.

99 itro phosphorylation assay for the efficient biochemical characterization of COT kinase inhibitors an

100 Here we report the purification and biochemical characterization of CTL4 and CTLMA2 from An.

101 Here we report biochemical characterization of CYP76M5, -6, and -8.

102 t experimental strategies: (1) isolation and biochemical characterization of cytoplasmic vesicles tha

103 metabolites accumulated by the mutants, and biochemical characterization of DH10 in vitro, using pol

104 ncy and function, we leveraged the extensive biochemical characterization of E26 transformation-speci

105 Biochemical characterization of each mutant revealed ste

106 We present the crystal structure and biochemical characterization of Escherichia coli YbiB, a

107 drug discovery, we report the synthesis and biochemical characterization of first covalent ligands d

108 here for the first time the identity and the biochemical characterization of four GAG-specific sulfat

109 Detailed biochemical characterization of four new enzymes reveale

110 This study shows how biochemical characterization of functionally important o

111 We report the structural and biochemical characterization of GLB-33, a putative neuro

112 erest in this protein, there has been little biochemical characterization of GSAP.

113 Biochemical characterization of heterologously expressed

114 Biochemical characterization of HjCel3A shows that the e

115 Biochemical characterization of HopM1 by mass spectromet

116 Here, we describe the biochemical characterization of Hpa2 and Hpa3 as bona fi

117 We performed a molecular and biochemical characterization of IFNlambda4 to determine

118 Here we report the biochemical characterization of influenza RdRP subcomple

119 Here we report the biochemical characterization of IpoC and PurCD.

120 Here, using biochemical characterization of isolated yeast vacuolar

121 These results are the first kinetic and biochemical characterization of JNK1beta1 and uncover so

122 Here we report the biochemical characterization of KedY4, confirming its pr

123 Here, we extend this knowledge through the biochemical characterization of KLF16, unveiling novel m

124 As a proof of concept, we performed a biochemical characterization of LipA from Xac306 and ver

125 From a biochemical characterization of M. thermautotrophicus Gl

126 In this study, we present our structural and biochemical characterization of MAIT TCR engagement of M

127 The biochemical characterization of mesophilic pAgo proteins

128 ssay will aid efforts toward a more detailed biochemical characterization of MshB.

129 The biochemical characterization of mutant assembly pathways

130 Here, we report the structural and biochemical characterization of MXAN_7475 (BacM), one of

131 Biochemical characterization of NadD confirmed its funct

132 sect these activities through structural and biochemical characterization of nuclear and cytoplasmic

133 Detailed biochemical characterization of nucleic acid enzymes is

134 histologic assessment of amyloid burden and biochemical characterization of oligomeric Abeta species

135 Here we present the first biochemical characterization of one of the paralog prote

136 We performed preliminary biochemical characterization of one of them, Brevibacill

137 Biochemical characterization of orthologs along the phyl

138 Here we present biochemical characterization of P-gp from Caenorhabditis

139 Here, we report the biochemical characterization of p14ARF tumor suppressor

140 e undertook clinical, neurophysiological and biochemical characterization of patients with mutations

141 s proven a major challenge toward a complete biochemical characterization of PCSK9's proteolytic func

142 In this study, extensive biochemical characterization of plant AAADs was performe

143 The biochemical characterization of point mutants in the GTP

144 Biochemical characterization of PolD1 and PolD2 shows th

145 Biochemical characterization of polyketide synthases (PK

146 Biochemical characterization of polymerase II isolated f

147 despread applications for the structural and biochemical characterization of PP-IP signaling properti

148 Our study provides the first biochemical characterization of prefibrillar myocardial

149 Here, we conducted phylogenetically informed biochemical characterization of prephenate aminotransfer

150 hat apply abundant structural information to biochemical characterization of protein translation and

151 Genetic and biochemical characterization of proteins bearing F231S a

152 Biochemical characterization of proteins that bind the T

153 Here we describe the biochemical characterization of purified and complete Sa

154 and serve as a "translation method" for the biochemical characterization of receptor-ligand interact

155 Here we present the biochemical characterization of recombinant Arabidopsis

156 Biochemical characterization of recombinant nucleosomes

157 Biochemical characterization of recombinant NudP reveale

158 A comparative biochemical characterization of rice (Oryza sativa) and

159 ithin LpxD and serves as a model for further biochemical characterization of RJPXD33 binding to LpxD.

160 Here, we present the biochemical characterization of several MspJI homologs,

161 d tumor suppressor gene in many cancers, yet biochemical characterization of several of its reported

162 e carried out an extensive spectroscopic and biochemical characterization of site-specific PU.1 ETS c

163 onfirmed the roles of these residues through biochemical characterization of site-specific variants.

164 Here, we report the isolation and biochemical characterization of spontaneously arising E.

165 Structural and biochemical characterization of T. potens and E. coli Is

166 Biochemical characterization of TgVP1 in enriched fracti

167 r level through structural determination and biochemical characterization of the aberrant enzymes.

168 present study, we performed a molecular and biochemical characterization of the AI-2 system in Yersi

169 constitution of ABCB6 into liposomes allowed biochemical characterization of the ATPase including (i)

170 ere, we present X-ray crystal structures and biochemical characterization of the Bacillus megaterium

171 tructure at 1.71 angstrom resolution and the biochemical characterization of the C-terminal domain of

172 sistance, here we undertook a structural and biochemical characterization of the CopG protein from Ps

173 Biochemical characterization of the corresponding recomb

174 Moreover, biochemical characterization of the cyclase revealed an

175 Here, we report the biochemical characterization of the direct interaction b

176 In this study, we describe the isolation and biochemical characterization of the DNA primase complex

177 Here, we report biochemical characterization of the encoded CPS and KS,

178 Despite resolved molecular structures and biochemical characterization of the enzyme from multiple

179 e RNase II is not known despite the advanced biochemical characterization of the enzyme.

180 overy of new carbohydrate modifications, the biochemical characterization of the enzymes involved in

181 Genetic and biochemical characterization of the ErbB2DeltaEx16-deriv

182 Here, we describe the crystal structure and biochemical characterization of the FNDC5 ectodomain, co

183 Our recent biochemical characterization of the GDP-6-deoxy-D-manno-

184 ere, we present x-ray crystal structures and biochemical characterization of the glutathione-dependen

185 Since then, the biochemical characterization of the inflammasomes has le

186 Biochemical characterization of the inhibitor revealed t

187 we have performed a detailed functional and biochemical characterization of the interaction between

188 Biochemical characterization of the IRF8(K108E) mutant i

189 The biochemical characterization of the L. major phosphatase

190 In this study, we report the biochemical characterization of the LSMT-like enzyme fro

191 Here we report a detailed biochemical characterization of the MsrQ protein from Es

192 Biochemical characterization of the mutant protein demon

193 Biochemical characterization of the mutant SecA proteins

194 The crystal structures and biochemical characterization of the NAD-dependent dehydr

195 genetic manipulation, and provide the first biochemical characterization of the oxidative cyclizatio

196 Biochemical characterization of the pomace extract showe

197 Here we describe the biochemical characterization of the prodrug synthesis, e

198 83 (here designated CmtA) was reexamined via biochemical characterization of the protein overproduced

199 AMY3 from Escherichia coli and carried out a biochemical characterization of the protein to find fact

200 s on both transfected and infected cells and biochemical characterization of the purified complex.

201 orated using the bacterial two-hybrid assay, biochemical characterization of the purified protein, an

202 Syt1 in insect cells along with an extensive biochemical characterization of the purified protein.

203 Biochemical characterization of the purified recombinant

204 Here we report a biochemical characterization of the R- and N-proteins.

205 Biochemical characterization of the recombinant AfSun1p

206 Biochemical characterization of the recombinant enzyme i

207 By in vivo gene inactivation and in vitro biochemical characterization of the recombinant enzyme T

208 The isolation of the mimosinase cDNA and the biochemical characterization of the recombinant enzyme w

209 The biochemical characterization of the recombinant GH8ErCel

210 In vitro biochemical characterization of the recombinant PDC1 enz

211 Biochemical characterization of the recombinant proteins

212 Biochemical characterization of the recombinant purified

213 d an extended substrate screen and extensive biochemical characterization of the recombinantly expres

214 molecular view of this interaction through a biochemical characterization of the respective protein c

215 Previous biochemical characterization of the resting form of NspF

216 nesis of Lys-234 in SHV, microbiological and biochemical characterization of the resulting beta-lacta

217 Comprehensive molecular and biochemical characterization of the resulting lines expr

218 Biochemical characterization of the RT-QuIC product indi

219 This work describes the biochemical characterization of the single-stranded DNA

220 Biochemical characterization of the Sln9 thioesterase do

221 Here, we describe studies on the biochemical characterization of the SNM1A and SNM1B prot

222 Here we report the biochemical characterization of the temperate bacterioph

223 In this work, we report the structural and biochemical characterization of the trans-enoyl-CoA redu

224 at are delivered to embryos, followed by the biochemical characterization of the transport of these c

225 Here, we report the isolation and initial biochemical characterization of the type-I RC from Ca. C

226 One reason for the paucity of structural and biochemical characterization of the VDAC2 and -3 isoform

227 Structural and biochemical characterization of the WT CYP105AS1 reveals

228 In this review, we summarize the biochemical characterization of these 8 radical S-adenos

229 Biochemical characterization of these enzymes along with

230 Biochemical characterization of these enzymes over the p

231 to libraries of glycoside hydrolases but the biochemical characterization of these enzymes remains ch

232 Genetic and biochemical characterization of these FIP1C-proficient a

233 Biochemical characterization of these potential sulfatas

234 Biochemical characterization of these variants revealed

235 yme as a protein kinase; however, a detailed biochemical characterization of this activity is lacking

236 ase activity has been reported, but thorough biochemical characterization of this activity is lacking

237 In line with this structural similarity, biochemical characterization of this effector, termed Tn

238 his study represents the first comprehensive biochemical characterization of this important O-linked

239 Biochemical characterization of three single mutants and

240 ding the terpene synthase TPS2 with this QTL Biochemical characterization of TPS2 verified that this

241 is study investigated the fine structure and biochemical characterization of trypsin from the viscera

242 Here, we provide a biochemical characterization of two ALDH12 family member

243 Here, we present the molecular and biochemical characterization of two cucumber copper ATPa

244 Herein, we report the isolation and biochemical characterization of two O-methyltransferases

245 This study describes the extraction and biochemical characterization of two proteases from the r

246 Despite structural and biochemical characterization of UbiX as a flavin mononuc

247 Phenotypic and biochemical characterization of various BamA L6 mutants

248 Herein, we report the biochemical characterization of VolA.

249 cus we used a genetic approach with detailed biochemical characterization of wax compounds.

250 Biochemical characterization of ZmCtl1 overexpressing li

251 Molecular and biochemical characterization of zmm28 transgenic plants

252 ganism on which the overwhelming majority of biochemical characterizations of bacterial RNA polymeras

253 Recent structural and biochemical characterizations of Smoothened domains have

254 Further biochemical characterizations of the automethylation-def

255 The biochemical characterizations of two new classes of comp

256 Our structural and biochemical characterizations provide an important frame

257 mmary, the results of our extensive in vitro biochemical characterization raise the possibility that

258 ins and prioritizing candidates for detailed biochemical characterization remain fundamental challeng

259 In vitro biochemical characterization revealed an additional role

260 Biochemical characterization revealed specific, tight bi

261 Biochemical characterization revealed that mutation of t

262 Biochemical characterization revealed that one mutation

263 Structural and biochemical characterization revealed that R262 plays a

264 Structural and biochemical characterization revealed that the MKK5 PB1

265 Detailed biochemical characterization revealed the series to be a

266 Subsequent biochemical characterization reveals that the mAbs bind

267 Biochemical characterization reveals that the mutant myo

268 ation experiments and a previously published biochemical characterization show that the bm2 gene enco

269 Our biochemical characterizations show that the periplasmic

270 Biochemical characterization showed a significant reduct

271 Biochemical characterization showed that G0S2 mediates p

272 Biochemical characterization showed that the compounds a

273 ial complexes or other relevant enzymes, and biochemical characterization showed that this compound i

274 Extensive biochemical characterizations showed that cleavage of gp

275 Biochemical characterization shows that the amyloid-beta

276 Biochemical characterization shows that the assembly of

277 Biochemical characterization shows that two homologs, te

278 Here we report the engineering, in vitro biochemical characterization, structural study, and in v

279 macokinetic (PK), toxicology, stability, and biochemical characterization studies of such drugs.

280 We show, via biochemical characterization, substrate analogues, and c

281 ctural model of human Insig-2, together with biochemical characterizations, suggest that the central

282 Further biochemical characterization suggested that the C-termin

283 Biochemical characterization suggested that the enzyme i

284 Structural, biophysical, and biochemical characterization support an allosteric mecha

285 Results from our biochemical characterizations support the assignment of

286 Despite extensive genetic and biochemical characterization, the molecular genetic basi

287 Despite their detailed biochemical characterizations, the degree to which each

288 MXAN_4832, and, based on its mutational and biochemical characterization, they may well represent an

289 action limit of the employed laser light and biochemical characterization through associated spectral

290 ronged approach of x-ray crystallography and biochemical characterization to elucidate the sequence-s

291 ar magnetic resonance (NMR) spectroscopy and biochemical characterization to reveal how RNF4 manipula

292 nd sequence-based phylogenetic analysis with biochemical characterization to survey the prevalence of

293 ral analysis, together with structure-guided biochemical characterization, uncovered how cytochrome c

294 d produced in Lactococcus lactis for further biochemical characterizations using phosphorylation assa

295 A biochemical characterization was carried out in knockdow

296 Biochemical characterization was performed for five modi

297 Through a series of EPR and biochemical characterizations, we found that MoaA cataly

298 Here, through structural and biochemical characterizations, we identified the replica

299 odeling, MD simulations, and biophysical and biochemical characterizations, we investigated the molec

300 Here, biochemical characterization with simplified substrate a