ライフサイエンスコーパス: biochemical mechanism

1 that is rooted in non-linear descriptions of biochemical mechanism.

2 known about its molecular components and its biochemical mechanism.

3 wn for decades, hindering elucidation of the biochemical mechanism.

4 cells is based on a biophysical as well as a biochemical mechanism.

5 areas for inquiry of basic physiological and biochemical mechanisms.

6 to selectively perturb or probe these basic biochemical mechanisms.

7 pulsivity in adulthood and examined possible biochemical mechanisms.

8 hallenges of "systems biology" as applied to biochemical mechanisms.

9 ing regulators that act through a variety of biochemical mechanisms.

10 odynamics and to delineate the corresponding biochemical mechanisms.

11 tion process characterized by changes in key biochemical mechanisms.

12 We propose a biochemical mechanism accounting for the dependency of m

13 A biochemical mechanism accounting for the Raman red shift

14 Biochemical mechanisms accounting for direct participati

15 While biochemical mechanisms activating actin network assembly

16 tween NGAL and its cellular receptor or in a biochemical mechanism allowing the receptor to discrimin

17 n in the nucleus may not be due to random or biochemical mechanisms alone, but may result from the tr

18 Small GTPases share a biochemical mechanism and act as binary molecular switch

19 mechanisms of action that are independent of biochemical mechanism and have implications for biomarke

20 i1-mediated actin assembly in vitro, but the biochemical mechanism and in vivo role of this activity

21 led by cell-cycle-dependent factors, but its biochemical mechanism and spatial regulation remain poor

22 Ancient microbes invented biochemical mechanisms and assembled core metabolic path

23 m biology is the study of quantum effects on biochemical mechanisms and biological function.

24 We also show that biochemical mechanisms and parameters together determine

25 The identification of biochemical mechanisms and prediction of patients at ris

26 little is known about LGR5 signaling nor the biochemical mechanisms and receptor determinants that re

27 ance and dependence are mediated by multiple biochemical mechanisms and that MOR endocytosis plays a

28 distinguishing feature of brown-rot, but the biochemical mechanisms and underlying genetics are poorl

29 ulation of UVB-induced COX-2, the underlying biochemical mechanisms are completely unknown.

30 of statin on the vascular functions, but the biochemical mechanisms are incompletely understood.

31 However, the underlying biochemical mechanisms are not known.

32 mpeting models arises commonly as underlying biochemical mechanisms are often not fully known, hence

33 Heterogeneous intracellular pathways and biochemical mechanisms are responsible for generating th

34 PUFA) may protect against breast cancer but biochemical mechanisms are unclear.

35 covery because their domain compositions and biochemical mechanisms are unique compared to the mammal

36 Because many of the biochemical mechanisms are unknown, this is a preliminar

37 ination in immune signaling pathways and the biochemical mechanisms as to how linear polyubiquitin ex

38 alytical tools capable of characterizing the biochemical mechanisms associated with chemically induce

39 s become possible to more precisely tune the biochemical mechanisms associated with using nonviral ve

40 nteractions is fundamental for understanding biochemical mechanisms at the molecular level.

41 The proposed biochemical mechanisms based on our findings provide imp

42 rch and faces challenges, mainly because the biochemical mechanisms behind the cancer-related VOCs ar

43 ale with cell size through both physical and biochemical mechanisms, but control systems that coordin

44 P-pVIc complexes along DNA illustrates a new biochemical mechanism by which a proteinase can locate i

45 there is a paucity of data available on the biochemical mechanism by which APOBEC3A deaminates ssDNA

46 together, these results demonstrate a novel biochemical mechanism by which ascorbate oxidation and t

47 Together, these results identify a biochemical mechanism by which ATF4 induces skeletal mus

48 However, the direct biochemical mechanism by which ATF4 promotes muscle atro

49 In this study, we investigate the biochemical mechanism by which ATF6alpha activates trans

50 However, little is known about the biochemical mechanism by which BIN2 phosphorylates its s

51 However, the biochemical mechanism by which E3 ubiquitination is impa

52 that controls axon pruning and elucidate the biochemical mechanism by which ephrin-B reverse signals

53 Together, these results identify a direct biochemical mechanism by which Gadd45a induces skeletal

54 However, the biochemical mechanism by which IreB modulates cephalospo

55 e silencing, little is known of the specific biochemical mechanism by which it inactivates transcript

56 The biochemical mechanism by which mutations in nucleotide-b

57 ponents, we demonstrate for the first time a biochemical mechanism by which Src phosphorylation of co

58 These results define a biochemical mechanism by which the BRCA1 enzymatic activ

59 A biochemical mechanism by which these transcription facto

60 The biochemical mechanism by which this single molecule cont

61 This study examined the biochemical mechanism by which vitamin D supplementation

62 n this study, we have begun to elucidate the biochemical mechanisms by which BTLA functions to inhibi

63 The structural and biochemical mechanisms by which EBNA1 allows the long-te

64 n implicated in many cellular processes, the biochemical mechanisms by which it influences these dive

65 However, biochemical mechanisms by which plants counteract NP tox

66 To gain insights into the biochemical mechanisms by which RON inhibits transcripti

67 sphatases to PD-1, little is known about the biochemical mechanisms by which these proteins contribut

68 These studies define cellular and biochemical mechanisms by which Vms1 locali-zation to mi

69 These findings uncover a conserved biochemical mechanism coupling nutrient status with auto

70 n of CheBs in pheromone response may involve biochemical mechanisms critical for lipid metabolism in

71 These results reveal a biochemical mechanism differentiating the endocytic acti

72 ivates these two related targets by the same biochemical mechanism: direct phosphorylation of a conse

73 While knowledge of the biochemical mechanisms driving this process has accumula

74 and illustrate the sophisticated variety of biochemical mechanisms employed in fine-tuning its redox

75 orted in plants, little is known about their biochemical mechanisms, especially their relationships w

76 bulky DNA adducts, we conclude that a common biochemical mechanism exists for activation of DNA-PK, A

77 ofacial and limb development and providing a biochemical mechanism for additive signaling requirement

78 cross multiple clonal processes and define a biochemical mechanism for altered 3'SS choice.

79 ther, these results establish a novel direct biochemical mechanism for ASMase activation in which PKC

80 pathway in BRAF(WT) cells but also offers a biochemical mechanism for BRAF oncogenesis.

81 The phosphoswitch provides a biochemical mechanism for circadian temperature compensa

82 ing residue was C315(7.38) and suggested one biochemical mechanism for covalent binding.

83 mage and, therefore, provide a new plausible biochemical mechanism for diabetic cardiomyopathy.

84 We examined here the biochemical mechanism for directional strand passage of

85 Here, we demonstrate a distinct biochemical mechanism for DNA break processing employed

86 We support our data with a plausible biochemical mechanism for modified bioenergetics that in

87 This provides a biochemical mechanism for MSC-derived resistance to foro

88 Our study provides a biochemical mechanism for MT-dependent MT amplification

89 Results of this study identify a novel biochemical mechanism for regulation of sMLA-induced gen

90 Beyond the recognition of an alternative biochemical mechanism for the biosynthesis of cyclic ter

91 ABPalpha and Gfi-1, and these data provide a biochemical mechanism for the generation of stable IL-7R

92 he cell-cycle machinery, thereby providing a biochemical mechanism for the genetic requirement for mu

93 These data provide a biochemical mechanism for the pathogenesis of this epile

94 Our data establish a biochemical mechanism for the role of Srs2 in crossover

95 Thus, our results provide a putative biochemical mechanism for the skeletal defects in human

96 This provides a biochemical mechanism for the VD-deficiency and potentia

97 The novel biochemical mechanism for these effects involves the abi

98 However, a biochemical mechanism for this effect has not been defin

99 However, the biochemical mechanisms for electron transport between th

100 acteria and eukaryotes have evolved distinct biochemical mechanisms for producing tetrahymanol.

101 Thus, this study lends insights on key biochemical mechanisms for regulating KLF sites involved

102 Although biochemical mechanisms for repairing several forms of ge

103 arge panel of hTR variants revealed numerous biochemical mechanisms for telomerase loss of function,

104 hin, and meso-zeaxanthin, but the underlying biochemical mechanisms for this spatial- and species-spe

105 uted to the understanding of the genetic and biochemical mechanisms for TMAO degradation in M. silves

106 r machine illustrate the limits of inferring biochemical mechanism from protein structure.

107 Consistent with this biochemical mechanism, genetic ablation of GATOR1 nullif

108 Despite its physiological importance, the biochemical mechanism governing Wnt acylation by Porcn i

109 s exist concerning the precise molecular and biochemical mechanisms governing these effects and the o

110 numbers of participating proteins and their biochemical mechanisms has made it possible to formulate

111 on stress and the presence of dehydrins, the biochemical mechanisms have remained somewhat elusive.

112 lasses, and our experiments suggest a common biochemical mechanism in binding and stabilizing distinc

113 se findings indicate that FITs have a unique biochemical mechanism in mediating LD formation and impl

114 n of the cone visual pigments via an elegant biochemical mechanism in Muller glial cells of the neura

115 Here, we describe a biochemical mechanism in which PARI functions as an HR r

116 Antibiotics target specific biochemical mechanisms in bacteria.

117 servation and the coupling of mechanical and biochemical mechanisms in stabilizing motile cells.

118 genetic coding capacity through a variety of biochemical mechanisms, including programmed ribosomal f

119 Our study illuminates the biochemical mechanisms involved in insect immunity to xe

120 Here, we delineate the biochemical mechanisms involved in NOTCH-induced JAK3 ub

121 e and fail to address pathophysiological and biochemical mechanisms involved with cartilage degenerat

122 s model insects to examine physiological and biochemical mechanisms involved with water balance, nutr

123 (MSC) cultures and delineate the underlying biochemical mechanisms involved.

124 man fetal brain, as well as the cellular and biochemical mechanisms involved.

125 Instead, biochemical mechanisms involving haploinsufficiency, dom

126 nt biotransformation reactions, but that the biochemical mechanism is not necessarily linked to ammon

127 ular dysfunction in the human heart, but the biochemical mechanism is poorly understood.

128 uch model involves a minimal number of known biochemical mechanisms: it basically relies on the inter

129 Biochemical mechanism leading from hyperglycemia to oxLD

130 of action of MMP-9 in cardiac tissue and the biochemical mechanisms leading to increased levels of MM

131 However, the biochemical mechanisms leading to the formation of this

132 unction in signaling pathways and downstream biochemical mechanisms leading to the PD phenotype.

133 The same thermodynamic and biochemical mechanisms linked to aging in somatic cells

134 l regulatory gene expression and providing a biochemical mechanism mediating O3-derived formation of

135 e is a major gap in our understanding of the biochemical mechanisms mediating their effects.

136 xperiments, this study demonstrates that the biochemical mechanisms modulated by two GCAPs in Ca(2+)

137 t histone methylation and acetylation as key biochemical mechanisms modulating KLF-mediated neurotran

138 gulate glucose uptake into cells, though the biochemical mechanism of action has been obscure.

139 biological and biochemical specificities and biochemical mechanism of action of EHT 1864.

140 Studies to identify its biochemical mechanism of action showed that it does not

141 enzymes allowed us to shed some light on the biochemical mechanism of aglycon cell growth inhibition,

142 The chemical nature, order, and biochemical mechanism of all the oxygenative tailoring r

143 Together, our results establish a biochemical mechanism of an Argonaute-dependent sRNA bio

144 However, bioactive fractions and biochemical mechanism of anti-fibrotic properties of rhu

145 NA and provides a testable hypothesis on the biochemical mechanism of cooperativity in protein assemb

146 Our data support the argument that the biochemical mechanism of Fe(III) reduction per se was no

147 ging questions in this regard relates to the biochemical mechanism of how exogenous environmental tri

148 mpartments critical for gene expression, the biochemical mechanism of how TDRD3 can affect the functi

149 We report here a biochemical mechanism of HURP regulation by Aurora A, a

150 The biochemical mechanism of MIIP in this process is associa

151 To elucidate the biochemical mechanism of miRNA processing, we developed

152 To better understand the biochemical mechanism of MYST autoacetylation and the im

153 Biochemical mechanism of NFIA function was evaluated usi

154 induced mTORC1 modulation and the underlying biochemical mechanism of NLK in mTORC1 inhibition in str

155 To gain insight into the biochemical mechanism of NTMT1, we have characterized th

156 Nevertheless, the biochemical mechanism of phy-induced PIF phosphorylation

157 Here, we interrogate the biochemical mechanism of procaspase-3 activation on 1541

158 tic properties of N348I RT and determine the biochemical mechanism of resistance to the NNRTI nevirap

159 Here we investigate the biochemical mechanism of RT inhibition and resistance to

160 nucleate the autophagosome membrane, but the biochemical mechanism of such nucleation activity remain

161 its TSS motif, revealing the structural and biochemical mechanism of synergistic activation of AURKC

162 nhibitors results in a working model for the biochemical mechanism of Tax-induced activation.

163 plications of active site flexibility on the biochemical mechanism of TcTS.

164 conformation and provides insights into the biochemical mechanism of the luciferase oxidative step.

165 Here, we investigated the biochemical mechanism of the Top1-induced short deletion

166 We applied MAP-C to further explore the biochemical mechanism of these contacts, and find they r

167 To explore the biochemical mechanism of this effect, we examined the ef

168 chemokine receptors including CCR5, but the biochemical mechanism of this process has not been fully

169 To understand the biochemical mechanism of this stimulation, we directly v

170 show that UGTs play an integral role in the biochemical mechanism of TNT detoxification by plants.

171 To understand the underlying biochemical mechanism of various exocytotic processes me

172 Our studies reveal a previously unrecognized biochemical mechanism of Vpx-mediated SAMHD1 inhibition:

173 In this study, we investigate the biochemical mechanism of wild-type RAF (RAF(WT)) activat

174 However, the exact biochemical mechanism of YUCs has remained elusive.

175 Here, we describe the structural and biochemical mechanisms of a bacteriophage immunity pathw

176 cell culture systems, and their cellular and biochemical mechanisms of action are known.

177 and has provided valuable insights into the biochemical mechanisms of action of compounds with prove

178 nder different conditions differentiated the biochemical mechanisms of action of distinct M3 antagoni

179 Although previous studies have clarified the biochemical mechanisms of antibiotic action, a physical

180 The biochemical mechanisms of cell growth inhibition by ITCs

181 understanding of the underlying genetic and biochemical mechanisms of cephalosporin resistance in E.

182 logy and evolution to genomics and molecular/biochemical mechanisms of development and reproduction.

183 The biochemical mechanisms of dual mutations include increas

184 h amino acid at each site lends insight into biochemical mechanisms of escape throughout the epitope,

185 into account in considering the genetic and biochemical mechanisms of frameshift mutagenesis in poly

186 Recent advances have helped understand the biochemical mechanisms of GlcNAc addition and removal an

187 The biochemical mechanisms of HNO activity are associated wi

188 Although substantial information about the biochemical mechanisms of intoxication exists, research

189 We investigated the biochemical mechanisms of KIC and leucine-stimulated ins

190 a valuable set of tools for delving into the biochemical mechanisms of lipid accumulation in algae an

191 features in T-cell progenitor cells, but the biochemical mechanisms of LMO2 function have not been fu

192 The functions and biochemical mechanisms of major classes of plant oxygena

193 thus requires a deeper understanding of the biochemical mechanisms of pathogenicity.

194 phytanic content during food production and biochemical mechanisms of phytanic acid metabolism, as w

195 ations and epigenetics can help separate the biochemical mechanisms of regulation from the inheritanc

196 ls of biological analysis did not reveal the biochemical mechanisms of response to ocean acidificatio

197 Recent studies have revealed biochemical mechanisms of SAMHD1-mediated retroviral res

198 te investigations aimed at understanding the biochemical mechanisms of TAG metabolism in plants.

199 The biochemical mechanisms of these pathways have been well

200 B, which may provide future insight into the biochemical mechanisms of these systems.

201 w we describe how such approaches reveal the biochemical mechanisms of three NAPs that are believed t

202 Biochemical mechanisms of tissue repair were activated i

203 ches will set a new standard for elucidating biochemical mechanisms of UB-driven signaling systems.

204 egment assortment, and genome encapsidation, biochemical mechanisms of virion morphogenesis within in

205 KRAS(G12D) may activate PI3Kalpha by direct biochemical mechanisms, PI3'-lipid signaling remains rat

206 validate and complete this study, understand biochemical mechanisms promoting sepsis development, and

207 ifications, which are carried out by similar biochemical mechanisms, regulate nearly every aspect of

208 ardiovascular disease, as well as on a novel biochemical mechanism regulating clot stability and diss

209 cted locations will aid in understanding the biochemical mechanisms regulating circulative virus tran

210 an lead to severe retinal pathology, but the biochemical mechanisms remain poorly defined.

211 om carnitine, the underpinning molecular and biochemical mechanisms remain unclear.

212 The underlying biochemical mechanisms remain unknown.

213 However, the underlying genetic and biochemical mechanisms remain unknown.

214 ve levels of induced plant defenses, precise biochemical mechanisms responsible for differing respons

215 To identify the biochemical mechanisms responsible for impaired insulin

216 for IMiD action, the complete molecular and biochemical mechanisms responsible for lenalidomide-medi

217 xylan synthesis through mutant analyses, the biochemical mechanisms responsible for synthesizing xyla

218 better characterize the underlying possible biochemical mechanisms responsible for the clinical find

219 In most cases, the biochemical mechanisms responsible for this signal speci

220 ses is necessary for characterization of the biochemical mechanism(s) for this class of enzymes.

221 n of activity patterns and investigations of biochemical mechanisms sensitive to physiological pertur

222 ne functionally accurate from the underlying biochemical mechanism standpoint.

223 Here, we review the biochemical mechanisms, structures, physiological functi

224 cribe its recombinant high level expression, biochemical mechanism, substrate preference, and regulat

225 The biochemical mechanism that coordinates filamentous actin

226 n in vitro transcription assay to identify a biochemical mechanism that explained the BRCA1 stimulato

227 these results identify a novel AKAP-mediated biochemical mechanism that increases TRPA1 sensitivity i

228 n vitro HtrA1 substrate suggests a potential biochemical mechanism that links ApoE4 regulation of AD

229 We also identify a biochemical mechanism that might contribute to this pola

230 phosphorylation is a ubiquitous, fundamental biochemical mechanism that regulates essential eukaryoti

231 The biochemical mechanisms that allow phytoplankton to limit

232 t phospholipid substitutions are fundamental biochemical mechanisms that allow phytoplankton to maint

233 iding important clues about the cellular and biochemical mechanisms that are active in normal and dis

234 Thus, genetic interactions can arise from biochemical mechanisms that calibrate morphogen signalin

235 mmation, and cancer, has fueled the study of biochemical mechanisms that control mitochondrial functi

236 tion is critical to our understanding of the biochemical mechanisms that control this critical tumor

237 ecessary to understand the physiological and biochemical mechanisms that enable these features as wel

238 However, the mechanical and biochemical mechanisms that ensure proper feedback contr

239 Yet the physical and biochemical mechanisms that govern this spatial heteroge

240 In contrast to the biochemical mechanisms that have been implicated in the

241 present some of the possible anatomical and biochemical mechanisms that influence the rapidity of st

242 ver, little is known about the molecular and biochemical mechanisms that initiate this shift.

243 A central question is the biochemical mechanisms that make LTP and LTD persistent.

244 lated amylin polymerization on membranes and biochemical mechanisms that protect beta-cells from amyl

245 The biochemical mechanisms that regulate the process of canc

246 een circadian gene expression cycles and the biochemical mechanisms that ultimately facilitate circad

247 To elucidate the biochemical mechanisms that underlie detoxification and

248 e described as a model for understanding key biochemical mechanisms that underlie development and dif

249 d is, therefore, essential to understand the biochemical mechanisms that underlie genomic regulation.

250 elicit plant defenses, but the molecular and biochemical mechanisms that underlie the activation of p

251 ew we discuss the discrete biomechanical and biochemical mechanisms that underlie these architectural

252 cts has led to a deeper understanding of the biochemical mechanisms that underlie these processes.

253 The biochemical mechanisms through which eosinophils contrib

254 g clinical link between folate and NTDs, the biochemical mechanisms through which folic acid acts dur

255 presented for elucidating the molecular and biochemical mechanisms through which sex-steroid hormone

256 ng, indicating that RPM-1 utilizes different biochemical mechanisms to bind these molecules.

257 Microbes and plants have evolved biochemical mechanisms to communicate with each other.

258 Blood-feeding parasites have developed biochemical mechanisms to control heme intake and detoxi

259 eneration of reactive oxygen species and the biochemical mechanisms to detoxify and repair the damage

260 rate that P. chrysosporium has the necessary biochemical mechanisms to drive 6:2 FTOH biotransformati

261 which will be widely employed to explore the biochemical mechanisms to further understand the dynamic

262 ternative protein sequences that use diverse biochemical mechanisms to perform the derived function a

263 contain a functional allele; hence, similar biochemical mechanisms underlie the rejection of both "s

264 lecular Cell, Shiotani and Zou elucidate the biochemical mechanism underlying sequential ATM and ATR

265 We dissected the biochemical mechanism underlying the requirement for NAI

266 However, the biochemical mechanism underlying the transition from DSB

267 The biochemical mechanism underlying these abnormalities was

268 The results indicate that the genetic and biochemical mechanisms underlying accumulation of medica

269 ractome of RNA modifications and reveals the biochemical mechanisms underlying m(6)A function in the

270 The basic biochemical mechanisms underlying many heritable human p

271 he lipidomic power for identification of the biochemical mechanisms underlying metabolic diseases.

272 Many of the molecular and biochemical mechanisms underlying methicillin resistance

273 ps in our understanding of the molecular and biochemical mechanisms underlying Mn homeostasis and neu

274 However, the intrinsic biochemical mechanisms underlying morphogenesis and seco

275 timuli modulate mTORC1 signaling, the direct biochemical mechanisms underlying mTORC1 regulation rema

276 uld greatly facilitate identification of the biochemical mechanisms underlying numerous pathological

277 es protein conformation and function and the biochemical mechanisms underlying PTH control of phospha

278 However, the biochemical mechanisms underlying Se methylation in micr

279 However, little is known about the biochemical mechanisms underlying T cell stimulation or

280 e suggests that oleamide participates in the biochemical mechanisms underlying the drive to sleep, th

281 t has been very difficult to investigate the biochemical mechanisms underlying the overlapping, multi

282 underscore the need to better understand the biochemical mechanisms underlying the temporal reconfigu

283 The biochemical mechanisms underlying their antitumor activi

284 However, the biochemical mechanisms underlying these double alteratio

285 The biological and biochemical mechanisms underlying these processes are no

286 animal model have prevented analysis of the biochemical mechanisms underlying this pathology.

287 d to human disease, and outline cellular and biochemical mechanisms underlying this phenomenon, incre

288 e data in our study reveal the molecular and biochemical mechanisms underpinning carnitine metabolism

289 ortance and power of the method for studying biochemical mechanisms underpinning disease states.

290 To understand the biochemical mechanisms underpinning DREAM function and r

291 nitrogen source; however, the molecular and biochemical mechanisms underpinning its growth remain un

292 The biochemical mechanisms used for dosage compensation must

293 he contribution of chromatin dynamics to the biochemical mechanisms utilized by these proteins to per

294 activate or repress promoters, although the biochemical mechanisms vary.

295 tion and pathogen tolerance, but the precise biochemical mechanism was unknown.

296 A novel approach for understanding the biochemical mechanism whereby RFUVA cross-linking stops

297 To identify the biochemical mechanisms whereby casein kinase1 (CK1) dete

298 GC B cells through both transcriptional and biochemical mechanisms, which collectively determine the

299 tabolic networks is governed by a variety of biochemical mechanisms, with inputs from other network n

300 n also facilitate elucidation of fundamental biochemical mechanisms within these systems.