ライフサイエンスコーパス: biofilm formation

1 lity, antagonism against other microbes, and biofilm formation.

2 ing virulence, antimicrobial resistance, and biofilm formation.

3 and a majority displayed collagen-dependent biofilm formation.

4 acterial functional amyloids assemble during biofilm formation.

5 nas aeruginosa, thus inducing chemotaxis and biofilm formation.

6 lling medical devices that provide sites for biofilm formation.

7 a basis for multicellular behaviors, such as biofilm formation.

8 m for studying regulatory networks directing biofilm formation.

9 rate act efficiently in preventing bacterial biofilm formation.

10 g the formation of long chains and increased biofilm formation.

11 ction and the stationary stage (phase 3) for biofilm formation.

12 n the surface of the foreign body and lesser biofilm formation.

13 sruption of icsA abolished bile salt-induced biofilm formation.

14 ted IcsA processing in biofilms and enhanced biofilm formation.

15 one of the SRRPs is sufficient for efficient biofilm formation.

16 adhesins mediate adhesion to substrates and biofilm formation.

17 ecological and medical relevance, including biofilm formation.

18 nders growth in seawater medium and inhibits biofilm formation.

19 lar domain and facilitated GAS adherence and biofilm formation.

20 system with spacers during the first 4 h of biofilm formation.

21 ulated genes involved in stress response and biofilm formation.

22 rsed this LCA-induced switch to chaining and biofilm formation.

23 adhesins, unexpectedly enhanced adhesion and biofilm formation.

24 was sufficient to preserve and even enhance biofilm formation.

25 which inhibits bacterial growth and prevents biofilm formation.

26 und infection to test its ability to prevent biofilm formation.

27 ibiotic susceptibility, toxin production and biofilm formation.

28 genous polyamines do not stimulate growth or biofilm formation.

29 lex did not significantly affect F. novicida biofilm formation.

30 rk, we show that MarA is also a regulator of biofilm formation.

31 via extensive cell-to-cell interactions and biofilm formation.

32 ion, remineralization of organic matter, and biofilm formation.

33 rtant for initial bacterial colonization and biofilm formation.

34 dation, protein glycosylation, motility, and biofilm formation.

35 ent of bacterial aggregates - a precursor to biofilm formation.

36 tion of ppx1 and ppx2 results in a defect in biofilm formation.

37 ich together repress genes for virulence and biofilm formation.

38 dressing itself has properties that minimize biofilm formation.

39 like autotransporter proteins in S. flexneri biofilm formation.

40 little is known about the regulation of SRB biofilm formation.

41 d may play a role in optimizing adhesion and biofilm formation.

42 ts in seawater medium and partially restores biofilm formation.

43 tyle adaptations such as persistence and the biofilm formation.

44 that products of the P2 genes also increase biofilm formation.

45 and icsA genes were generated and tested for biofilm formation.

46 which enable virulence factor expression and biofilm formation.

47 virulence, stress responses, metabolism and biofilm formation.

48 iated cell lysis contributes to C. difficile biofilm formation.

49 of respiratory processes elicited increased biofilm formation.

50 es, including the ability to alter bacterial biofilm formation.

51 virulence, interbacterial interactions, and biofilm formation.

52 phenotypes including virulence, motility and biofilm formation.

53 a would promote C difficile colonization and biofilm formation.

54 hromosome I), only the latter contributed to biofilm formation.

55 ver, protein synthesis was required for full biofilm formation.

56 lack of serine results in the initiation of biofilm formation.

57 acterium for understanding the principles of biofilm formation.

58 y leading to accumulation of bacteria during biofilm formation.

59 te cellular adhesion, electronegativity, and biofilm formation.

60 f native PNAG is critical for PNAG-dependent biofilm formation.

61 Staphylococcus epidermidis (S. epidermidis) biofilm formation.

62 s, as they are often the result of bacterial biofilm formation.

63 ultures demonstrate up to a 70% reduction in biofilm formation.

64 HDM could inhibit the growth of bacteria and biofilms formation.

65 HnoX may inhibit colonization by controlling biofilm formation, a key early step in colonization.

66 t stains of S. aureus with varying degree of biofilm formation ability was studied in an established

67 A damage, and control of central metabolism, biofilm formation, acid stress resistance, and other fun

68 -2, a quorum sensing molecule that modulates biofilm formation across many bacterial species.

69 nically prevent the first stage in bacterial biofilm formation, acting as on-demand fouling release a

70 ated proteins (BAPs) are important for early biofilm formation (adhesion) by bacteria and are also fo

71 racterized an isolate that exhibited greater biofilm formation, aggregation and oyster colonization t

72 sing (QS) systems that control virulence and biofilm formation among other traits.

73 sociation between virulence determinants and biofilm formation among phage susceptible A. baumannii s

74 s virulence, host colonization, sporulation, biofilm formation, among others.

75 reas others act as inverse agonists reducing biofilm formation and antibiotic tolerance, both in vitr

76 ovides detailed insights into S. epidermidis biofilm formation and architecture that improve our unde

77 ition of bacteria is a critical stage during biofilm formation and biofouling development in membrane

78 wn to be necessary and sufficient for mature biofilm formation and catheter infection.

79 n of SA enhanced the production of H(2)S and biofilm formation and Cd(II) adsorption.

80 the wound at time of injury are critical for biofilm formation and chronic wound development and may

81 rategies to inhibit surface sensing, prevent biofilm formation and control persistent infections.

82 The addition of NO abrogated biofilm formation and diminished syp transcription, effe

83 o cholerae biofilms are hyperinfectious, and biofilm formation and dispersal are considered central t

84 We develop a live-cell biofilm formation and dispersal assay that allows examin

85 The decision between biofilm formation and dispersal is mediated by LapD, a c

86 rial motility (twitching), surface adhesion, biofilm formation and DNA uptake (natural transformation

87 porated drug delivery systems for inhibiting biofilm formation and eradicating formed biofilms.

88 ug delivery systems as an approach to target biofilm formation and eradication.

89 ion of F nucleatum also enhanced C difficile biofilm formation and extracellular polysaccharide produ

90 TapA is a secreted protein also needed for biofilm formation and helps in vivo TasA-fibre formation

91 c regulation is associated with cell length, biofilm formation and host colonization.

92 Sensing these signals leads to altered biofilm formation and increased tolerance to various ant

93 ing dentifrices are effective in controlling biofilm formation and maintaining gingival health; howev

94 which contributes to bacterial colonization, biofilm formation and maintenance, and pathogenesis.

95 ialdehyde (MDA) production and a decrease in biofilm formation and metabolic activity of the bacteria

96 t adaptation, related to changes observed in biofilm formation and metabolic capacity.

97 sion for many bacteria is the switch between biofilm formation and motile dispersal, and this dynamic

98 experimental data for genes associated with biofilm formation and motility.

99 aimed to evaluate the Staphylococcus aureus biofilm formation and Nepsilon-carboxymethyl-lysine gene

100 s have been studied in detail with regard to biofilm formation and pathogenesis, the exopolysaccharid

101 enhances epithelial cell invasion, in vitro biofilm formation and persistence in urinary tract infec

102 roles ranging from plasmid stabilization to biofilm formation and persistence.

103 dynamic inactivation (PDI) to avoid bacteria biofilm formation and prevent VAP occurrence during trac

104 tisfying the coincidence detector to repress biofilm formation and promote dispersal.

105 ltappiB) mutant strain demonstrates impaired biofilm formation and reduced motility.

106 The deletion of mpaR increased biofilm formation and reduced pyocyanin production.

107 s, the mechanisms of Pseudomonas fluorescens biofilm formation and regulation have emerged as among t

108 pographies with the optimized design prevent biofilm formation and remove established biofilms of uro

109 n addition, exposure to CSE induced enhanced biofilm formation and resistance to the antibiotic levof

110 r biosynthesis, regulation, contributions to biofilm formation and stability of the matrix, and immun

111 o human health, although adaptations towards biofilm formation and surface interactions were observed

112 We also found association between biofilm formation and the presence of ompA gene among ph

113 ecB, are essential structural components for biofilm formation and thus render a possible anchor for

114 tate of the disulfide bond affects S. aureus biofilm formation and toxic shock syndrome toxin-1 produ

115 Pa biofilm formation and viability were elevated in conditi

116 rum sensing represses Pseudomonas aeruginosa biofilm formation and virulence by activating expression

117 mall RNA, which represses genes required for biofilm formation and virulence factor production.

118 d, exposing P. aeruginosa to light represses biofilm formation and virulence gene expression.

119 gated whether YrInv and YrIlm play a role in biofilm formation and virulence.

120 isovaleric acid to S. epidermidis inhibited biofilm formation and, similarly to C. acnes supernatant

121 Overproduction of LapG inhibited biofilm formation and, unlike the wild-type parent, a De

122 or integrins, integrin-binding proteins, and biofilm formation, and (3) in sequence pattern searching

123 s involved in mating, filamentous growth and biofilm formation, and also influences cAMP-regulated pr

124 witch, e.g., between virulence, sporulation, biofilm formation, and cell division.

125 r their cytotoxicity, mechanical properties, biofilm formation, and fluoride release.

126 weathering, secondary mineral precipitation, biofilm formation, and grain coatings across the three c

127 hat locked VRE in diplococcal mode, impaired biofilm formation, and increased susceptibility to the a

128 exhibited a lower growth rate and increased biofilm formation, and interestingly, these phenotypes w

129 ion in SPLUNC1 affecting mucosal attachment, biofilm formation, and invasion of mucosal epithelial ce

130 peptides inhibits bacterial growth, prevents biofilm formation, and leads to the recruitment of neutr

131 RpoN* expression reduced motility, biofilm formation, and pathogenesis in a P. aeruginosa-C

132 effectors that promote nutrient acquisition, biofilm formation, and pathogenicity.

133 auxotrophy, polyamine-independent growth and biofilm formation, and presence of functional polyamine

134 significantly enhanced intestinal adherence, biofilm formation, and pro-inflammatory interleukin-8 se

135 fundamental interest, including metabolism, biofilm formation, and sporulation.

136 cteria have roles in cell-to-cell signaling, biofilm formation, and stress responses.

137 iates adherence, colonization, motility, and biofilm formation, and the major protein subunit, PilA,

138 ting this result, deleting dvu2956 increased biofilm formation, and this biofilm phenotype could be c

139 ntion of bacterial attachment and subsequent biofilm formation, and thus are promising in circumventi

140 r, antifungal, and bactericidal actions, and biofilm formation, and to use as a molecular probe.

141 lR deletion strain is defective in motility, biofilm formation, and tumorigenesis of potato discs.

142 P3 promoters of the agr operon and increase biofilm formation, and two of these compounds also showe

143 Agd3, leads to defects in GAG deacetylation, biofilm formation, and virulence.

144 both early and late stages of S. epidermidis biofilm formation, and we confirmed that extracellular f

145 rences in their responses to PF in motility, biofilm formation, antibiotic susceptibility, osmotic st

146 ple sugars, fungal cell wall deconstruction, biofilm formation, antimicrobials biosynthesis, and meta

147 Bacterial swarming and biofilm formation are collective multicellular phenomena

148 tural and regulatory components required for biofilm formation are known, it is not understood how th

149 obial community assembly during the granular biofilm formation are poorly understood, and little is k

150 rived from LBG supported better Lactobacilli biofilm formation as compared to KG hydrolysate containi

151 ts application to studies of cell growth and biofilm formation, automated in silico control of optoge

152 bacterial binding to collagen and to enhance biofilm formation, both of which are important for A. ac

153 This reduced acute virulence and enhanced biofilm formation, both of which are phenotypic changes

154 gative regulators control syp expression and biofilm formation, but until recently the environmental

155 ) ), we found production of DVU2956 inhibits biofilm formation by 70%.

156 ct quorum sensing signaling chemicals during biofilm formation by a Gram-negative bacterial species.

157 st genes that are upregulated in response to biofilm formation by B. subtilis.

158 Biofilm formation by Bacillus subtilis is a communal pro

159 Biofilm formation by bacterial pathogens is associated w

160 The problem is exacerbated by biofilm formation by bacterial pathogens on the surfaces

161 Biofilm formation by CLs has been observed on the outer

162 ssion of surface polysaccharides may promote biofilm formation by F. tularensis Types A and B.

163 ecent rise in antibiotic drug resistance and biofilm formation by microorganisms has driven scientist

164 ed that recombinant SPLUNC1 protein inhibits biofilm formation by Nm, and impedes Nm adhesion and inv

165 s the current understanding of LapA-mediated biofilm formation by P. fluorescens and discusses severa

166 Biofilm formation by P. fluorescens occurs through the l

167 dogenous (biosynthetic) L-arginine influence biofilm formation by P. putida through changes in c-di-G

168 The biofilm formation by Pseudomonas aeruginosa highly incre

169 Biofilm formation by Pseudomonas aeruginosa, a leading c

170 to create coatings found to be resistant to biofilm formation by six different bacterial pathogens:

171 s are difficult to diagnose and treat due to biofilm formation by the causative pathogens.

172 A on ycgZ-ymgABC expression are coupled with biofilm formation by the rcsCDB phosphorelay system, wit

173 iofilm and a mechanism for the inhibition of biofilm formation by V. fischeri.

174 Biofilm formation by Vibrio cholerae facilitates environ

175 GMP levels, restricted motility and promoted biofilm formation, c-di-GMP levels were decreased in Del

176 m sensing inhibitors (QSIs) interfering with biofilm formation can thus complement antibiotics.

177 We also found differences in biofilm-formation capability between isolates and observ

178 , we observe adaptation towards an increased biofilm formation capacity and genetic diversification o

179 processes in S. aureus, including autolysis, biofilm formation, capsule synthesis and virulence.

180 Biofilm formation causes prolonged wound infections due

181 piratory epithelial cell surface and inhibit biofilm formation, causing biofilm disruption and thereb

182 rain had rough colony morphology and reduced biofilm formation compared with the WT strain; however,

183 between isolates and observed that increased biofilm formation correlated with mutations in the putat

184 The effect of both IATs on biofilm formation correlated with the presence of differ

185 different experiments either during or after biofilm formation directly on a microdialysis probe.

186 um sensing molecules produced during in situ biofilm formation directly on the polymeric semipermeabl

187 op a flexible computational model for E.coli biofilm formation driven by Autoinducer 2 (AI-2) which i

188 Whether biofilm formation enhances survival of F. tularensis in

189 etiologic factor in dental implant failure, biofilm formation, enhancing electrochemical behavior of

190 t, and our spatial hybrid Petri net model of biofilm formation, first presented at the NETTAB 2017 wo

191 Though biofilm formation has been studied for decades, tracing

192 anics, while being central to the process of biofilm formation, have been overlooked as a factor infl

193 olved in similar functions such as motility, biofilm formation, host colonization, and immune evasion

194 , and 32 ug/mL, respectively), and inhibited biofilm formation (IC(50) 1 ug/mL) in S. aureus.

195 A. spinosa extracts inhibited biofilm formation (IC(50) 2 ug/mL) and quorum sensing (I

196 L. tulipifera extracts inhibited biofilm formation (IC(50) 32 ug/mL) in S. aureus.

197 bacteria use AHL to coordinate virulence and biofilm formation in a cell density-dependent manner; th

198 in the impact of extracellular proteases on biofilm formation in a LAC msa mutant.

199 turn alters the balance between motility and biofilm formation in Acinetobacter.

200 Quorum sensing drives biofilm formation in bacteria in order to ensure that bi

201 beta-amino derivatives significantly inhibit biofilm formation in both species.

202 EmaA enhanced biofilm formation in different strains, independent of t

203 s, leading to efficient cell aggregation and biofilm formation in homogenous populations.

204 These lipids contribute to biofilm formation in M. tuberculosis and M. smegmatis, a

205 ayed consistent bacterial mucus invasion and biofilm formation in mouse colons.

206 can minimize bacteria accumulation prior to biofilm formation in new and cleaned FO membrane systems

207 c-di-GMP signaling and effectively inhibits biofilm formation in Pseudomonas aeruginosa, the most wi

208 On-farm microevolution resulted in enhanced biofilm formation in subsequent production cycle.

209 and inhibit (at 10 mM, 20 mM and 40 mM) new biofilm formation in the absence of an antibiotic.

210 However, the role of biofilm formation in the life cycle of these pathogens r

211 n and rhamnolipids production as well as the biofilm formation in the pnp mutant.

212 r (agr) QS system plays an important role in biofilm formation in this opportunistic pathogen, and th

213 deed, the deletion of hnoX resulted in early biofilm formation in vitro, an effect that was dependent

214 and assessed for hydroxyapatite binding and biofilm formation in vitro.

215 s and nitrite inhibited S. mutans growth and biofilm formation in vitro.

216 e to CS, namely growth inhibition, augmented biofilm formation, increased invasion of, and persistenc

217 mpeding bacterial adhesion to host cells and biofilm formation, interrupting or inhibiting bacterial

218 Bacterial biofilm formation involves signaling and regulatory path

219 Biofilm formation is a co-operative behaviour, where mic

220 Biofilm formation is a key mechanism of antimicrobial re

221 Biofilm formation is a key virulence factor responsible

222 Thus, biofilm formation is a survival strategy in long-term in

223 Early stage detection of biofilm formation is an important aspect of microbial re

224 However, in this study, we found that the biofilm formation is decreased in the pnp mutant, which

225 results support the expected behaviour that biofilm formation is increased in areas of higher bacter

226 The biofilm formation is positively regulated by two small R

227 Biofilm formation is regulated by 3',5'-cyclic diguanyla

228 nsities, when autoinducers have accumulated, biofilm formation is repressed, and dispersal occurs.

229 ure of a late stage biofilm, suggesting that biofilm formation is severely hampered in the natural en

230 ily, but its potential role in Pel-dependent biofilm formation is unknown.

231 While biofilm formation is well studied, almost nothing is kno

232 SagS key amino acid residues associated with biofilm formation (L154) and antibiotic tolerance (D105)

233 e K treatment uncoupled electron uptake from biofilm formation, likely through proteolytic degradatio

234 is as well as the potent inhibition of SBW25 biofilm formation mediated by the PFLU1114 operon.

235 Biofilm formation mediated by the syp gene cluster helps

236 , second-messenger turnover, quorum sensing, biofilm formation, motility, host-pathogen and beneficia

237 sing from acquired resistance and/or through biofilm formation necessitate the development of innovat

238 CLJ enhanced biofilm formation of most C. coli strains and supported

239 te cell wall hydrolase genes and disrupt the biofilm formation of MRSA clearly indicated that Inh2-B1

240 we hypothesized that C. acnes may influence biofilm formation of S. epidermidis.

241 a predictive QSAR is reported for bacterial biofilm formation on a range of polymers, using calculat

242 d systems, focusing on (i) granulation; (ii) biofilm formation on carrier materials; (iii) gel entrap

243 reduce the rate of P. mirabilis crystalline biofilm formation on catheters, and increase the time ta

244 assays revealed that YrInv and YrIlm promote biofilm formation on different abiotic substrates.

245 Microbial biofilm formation on indwelling medical devices causes p

246 mediate GAS attachment to and enhancement of biofilm formation on matrices deposited by cancer-associ

247 hese results shed light on the first step of biofilm formation on the membranes in AnMBRs and emphasi

248 dpoints assessed were: bacterial counts, and biofilm formation on the surface of the foreign body.

249 cterium Vibrio fischeri depends on bacterial biofilm formation on the surface of the squid's light or

250 in situ the effect of this dietary sugar on biofilm formation on titanium surface.

251 ormation in bacteria in order to ensure that biofilm formation only occurs when colonies are of a suf

252 pment and screening either do not facilitate biofilm formation or are cumbersome to operate, need lar

253 otypes such as cell morphology, motility and biofilm formation over extended periods of time.

254 description of quorum sensing and associated biofilm formation over two phases of bacterial growth, t

255 a holistic transcriptional regulation (e.g., biofilm formation, oxidative stress defense) when grown

256 Analyses of biofilm formation, previously reported to be higher in A

257 atures that drive biofilm resilience and the biofilm formation process at single-cell resolution.

258 literature-based case study considering the 'biofilm formation process' in Pseudomonas aeruginosa.

259 In this study, we showed that polymicrobial biofilm formation promoted the tolerance of Porphyromona

260 llective, multicellular behaviors, including biofilm formation, quorum sensing, nutrient acquisition,

261 detect the integrins, integrin-binding, and biofilm formation-related proteins on a reserved set of

262 rns of bacteria during the initial stages of biofilm formation remain unclear.

263 single-cell level during the early stage of biofilm formation remain understudied.

264 oids, but the role of individual PSMs during biofilm formation remains poorly understood and the mole

265 against S. aureus infection associated with biofilm formation remains to be elucidated.

266 Eliciting biofilm formation required coating fetal bovine serum on

267 Our results indicate that Pel-dependent biofilm formation requires a UDP-GlcNAc C4-epimerase tha

268 In Bacillus subtilis, robust biofilm formation requires large quantities of ferric ir

269 acteristics, favoring twitching motility and biofilm formation, respectively.

270 n competition via bacteriocin production nor biofilm formation showed any apparent relationship with

271 phosphodiesterase, PdeV, whose loss promotes biofilm formation similar to that of the DeltalapG mutan

272 Antibiotic susceptibility, biofilm formation, Staphylococcal protein A (spa) typing

273 tion of virulence-related genes that control biofilm formation, streptolysin S (SLS)-mediated hemolys

274 a recently identified positive regulator of biofilm formation, suggested that HnoX may inhibit colon

275 Ms have evolved to ensure fast and efficient biofilm formation through cooperation between individual

276 including norspermidine, eventually inhibit biofilm formation through inhibition of planktonic growt

277 -regulated by acylation but are required for biofilm formation, thus providing a defined role for thi

278 ates a wide range of cellular functions from biofilm formation to growth and survival.

279 be present simultaneously for repression of biofilm formation to occur.

280 eria, influencing cellular processes such as biofilm formation, transcription, virulence, quorum sens

281 ity, efflux pumps, antimicrobial resistance, biofilm formation, two-component systems (TCSs), capsule

282 viors, including bioluminescence production, biofilm formation, virulence factor secretion systems, a

283 er important for major phenotypes, including biofilm formation, virulence, and antibiotic tolerance.

284 Biofilm formation was enhanced in a LAC msa mutant by re

285 EmaA-mediated biofilm formation was found to be independent of the gly

286 Biofilm formation was highly variable but had a strong p

287 controlled by DVU2956 (dvu2960 and dvu2962), biofilm formation was inhibited almost completely.

288 MP levels were decreased in Deltapa2072, and biofilm formation was inhibited, compared to wild type.

289 f cholate, suggesting that the robustness of biofilm formation was inversely correlated with IcsA pro

290 evated in conditioned media from CF MDMs and biofilm formation was reduced in the presence of conditi

291 e expression of pelX under these conditions, biofilm formation was unaffected in a DeltapelX strain.

292 production, which is critical for S. mutans biofilm formation, was also inhibited in 2-species biofi

293 After media optimization for biofilm formation, we demonstrated that Lcr attaches to

294 phylococcus aureus and genetic signatures of biofilm formation were associated with poor outcomes.

295 ; however, both normal colony morphology and biofilm formation were restored in a Deltausp (4207)Delt

296 trical signals, which represent the onset of biofilm formation, were dynamically detected by the DGTF

297 Pseudomonas aeruginosa are characterized by biofilm formation, which effectively enhances resistance

298 s showed differential twitching motility and biofilm formation while maintaining the ability to adher

299 systems during early colonization phase and biofilm formation, while low c-di-GMP levels unleash T6S

300 l deposition of anaerobes, the first step in biofilm formation, with a consortium isolated from an An