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1 ne expression data) are ubiquitous in modern bioinformatics.
2 that can be answered when utilizing NGS and bioinformatics.
3 ds and identified KIR genotypes using custom bioinformatics.
4 cations of supervised learning approaches in bioinformatics.
5 ilarity is a central challenge in structural bioinformatics.
6 ild-type and E571K CRM1 with structure-based bioinformatics.
7 e current sequence and structural methods in bioinformatics.
8 to be published in this special issue of BMC Bioinformatics.
9 en BCREval and Bismark (Krueger and Andrews, Bioinformatics 27:1571-1572, 2011), a widely used BCR ev
10 product (syn-BNP) approach, which relies on bioinformatic algorithms followed by chemical synthesis
11 Lite backend and its input is generated from bioinformatic algorithms reliably described in the liter
12 types, brain tissue regions and advances in bioinformatics algorithms, have presented an opportunity
14 oimmunoprecipitation, mass spectrometry, and bioinformatic analyses indicate 14-3-3 is associated wit
18 of horizontal gene transfer (HGT) relying on bioinformatic analyses of genetic elements maintained on
22 nrolled in the NIH Lung HIV studies and used bioinformatic analyses to investigate whether signature
25 kflows, by helping to reduce overhead during bioinformatic analyses, preventing costly bioinformatic
28 Using extensive computational sequence and bioinformatics analyses and cellular localization studie
37 e conducted to identify genetic variants and bioinformatics analyses were performed to prioritize can
38 ries on murine ovaries, coupled with several bioinformatics analyses, the complete dynamic genetic pr
48 sing availability of cyanobacterial genomes, bioinformatic analysis has revealed the existence of a n
55 design principle to guide bioengineering and bioinformatic analysis of SD, and illuminates the fundam
69 Preliminary functional studies, including bioinformatics analysis and TOP-/FOP-flash reporter assa
91 c phage were analyzed by deep sequencing and bioinformatics analysis to identify a total of 78 300 +/
95 ally expressed genes and pathways in ESCC by bioinformatics analysis, potentially providing valuable
105 tion, these protocols are not in wide use in bioinformatics and are difficult to use for even technol
106 era, one of the most challenging problems in bioinformatics and computational biology is to computati
107 Despite these sobering statistics, most bioinformatics and computational biology research and fu
110 Pedigree files are ubiquitously used within bioinformatics and genetics studies to convey critical i
112 is particularly crucial for applications to bioinformatics and medical informatics, namely covariate
115 geting users with intermediate experience in bioinformatics and statistics and using R with Bioconduc
119 dem affinity purification-mass spectrometry, bioinformatics, and biochemical approaches, we found tha
120 ence comparisons have become popular in many bioinformatics applications, specifically in the estimat
123 cells by CyTOF, and use a 'nearest neighbor' bioinformatics approach to trace cells to their original
124 discuss methods that could be implemented in bioinformatic approaches for curation to ensure that met
128 egories requires appropriately sophisticated bioinformatics approaches and thorough validation in div
129 ering procedure in CNV studies with suitable bioinformatics approaches can identify ADHD candidate ge
132 n language, or amino acids or nucleotides in bioinformatics, are generally represented as a continuou
133 ich has spurred a rapid growth in the use of bioinformatics as a means of interrogating antibody vari
135 d flow cytometry analysis was validated with bioinformatics-based analysis and machine learning algor
136 ide-copper complexes, while a combination of bioinformatics-based structure modelling, Cu(2+) ion doc
137 ad data for control DNA samples to allow for bioinformatic benchmarking by users developing pipelines
139 equencing (scRNA-seq) data are ubiquitous in bioinformatics, but using single clustering or classific
141 ortunities provided by genome sequencing and bioinformatics, challenges associated with translating g
146 e, which serves as a blueprint to reduce the bioinformatic complexity associated with repetitive TEs
147 ropose a model that bridges experimental and bioinformatics concepts using the Oxford Nanopore Techno
148 Rules to follow when writing an algorithmic bioinformatics conference paper to avoid having it rejec
152 wth is abolished at ambient CO(2) We present bioinformatic data suggesting that the malate cycle may
154 lections, but also to ensure linkage between bioinformatic databases and the wider research community
156 ored the biology of co-expressed genes using bioinformatics databases, and identified known drug-gene
157 of top-ranked predictors in high-dimensional bioinformatics datasets, in order to avoid the potential
158 also highlight the present inadequacy of the bioinformatic definition of lncRNA, which excludes those
160 This protocol reports both experimental and bioinformatic details to perform AQuA-HiChIP, going from
161 nutraceutical leads were identified through bioinformatic drug repurposing analyses (such as pioglit
162 w drug candidates and natural compounds upon bioinformatics drug repurposing analyses, such as calciu
164 and considerations for setting up an NGS and bioinformatics-focused infectious disease research publi
166 xt generation sequencing (NGS) combined with bioinformatics has successfully been used in a vast arra
167 in molecular biology, optics, genetics, and bioinformatics have opened the door to mapping, in molec
168 reveal a shared set of properties for facile bioinformatic identification of new anti-CRISPR families
170 ever, implementation of high-quality NGS and bioinformatics in research and public health laboratorie
171 r Biotechnology Information (NCBI), European Bioinformatics Institute (EBI) and the DNA Data Bank of
172 applications of deep learning algorithms in bioinformatics is increasing as they usually achieve sup
175 usage of embeddings is well described in the bioinformatics literature, the potential of end-to-end l
177 ion from microscopy, structural biology, and bioinformatics may be integrated to build structural mod
179 m and the sequencing approach, the choice of bioinformatics methodologies, access to the appropriate
182 ng bioinformatic analyses, preventing costly bioinformatic mistakes, and promoting computational repr
183 RNA discovery using profiling techniques and bioinformatic modeling of the network effect of multiple
186 charomyces cerevisiae using a combination of bioinformatics, mutational experiments, and evolutionary
187 is underexploited resource using a synthetic-bioinformatic natural product (syn-BNP) approach, which
195 >=9 kb were sequenced and analyzed through a bioinformatic pipeline to detect indels, frameshifts, or
196 olyreactive antibody sequences, we created a bioinformatic pipeline to isolate key determinants of po
197 ng more than 20 billion reads) and a uniform bioinformatic pipeline to produce comprehensive sRNA loc
199 genetic variants (SparkINFERNO), a scalable bioinformatics pipeline characterizing non-coding genome
200 raction-based microbiome discovery (CSMD), a bioinformatics pipeline specifically developed to genera
207 Recent advances in sequencing technology and bioinformatic pipelines have allowed unprecedented acces
209 s the potential to improve the robustness of bioinformatics pipelines for surveillance and could be a
211 addition, we discuss the range of potential bioinformatics pipelines, including structural and funct
212 mmand-line interface readily integrates into bioinformatics pipelines, the intuitive web front-end wi
217 med linkage disequilibrium (LD) analysis and bioinformatic prediction to screen functional SNPs linke
218 we also performed functional annotations by bioinformatics prediction and expression quantitative tr
219 time-lapse microscopy, genetic perturbation, bioinformatic predictions, and mathematical modeling.
220 on that also will support the improvement of bioinformatics predictors, which critically relies on th
223 The US Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB) serves many
224 y RNA sequencing (RNA-Seq), with appropriate bioinformatics, provides a robust tool to identify addit
226 method for library preparation coupled with bioinformatic removal of globin gene counts is sufficien
227 ue to be rapidly generated, a major focus of bioinformatics research has been aimed toward integratin
229 arch infrastructures, can describe their own bioinformatics resources and share these via bio.tools.
230 ion for life science that aims to coordinate bioinformatics resources in a single infrastructure acro
232 e great venues for disseminating algorithmic bioinformatics results, but they unfortunately do not of
235 nd IFI44L as possible genes of interest in a bioinformatic screen, we dissected the function of these
240 lly for researchers who do not specialize in bioinformatics skills or do not have access to expensive
241 ta in any genomic region without need of any bioinformatics skills or special computing resources.
242 d among researchers in molecular ecology for bioinformatic software that will not only condense outpu
246 nificantly improve performance in downstream bioinformatics studies and biomedical text-mining applic
249 Here we report a functional, structural, and bioinformatics study of Mtb enzymes initiating cholester
251 ed in core support facilities when providing bioinformatics support, drawing on our own experiences w
253 ncluding single-cell mRNA-sequence analysis, bioinformatics, synthetic biology and high-throughput fu
255 NASQAR is a collaboration between the core bioinformatics teams of the NYU Abu Dhabi and NYU New Yo
256 n editorial report of the supplements to BMC Bioinformatics that includes 6 papers selected from the
257 d how this information can be used alongside bioinformatics to understand mechanisms of binding and i
258 we present MI-MAAP, an easy-to-use web-based bioinformatics tool designed to prioritize informative m
261 development of the experimental methods and bioinformatics toolkits that have provided a fuller unde
262 tely analyzed due to a lack of sophisticated bioinformatic tools and field-specific biological expert
266 any symbiotic system, but there are very few bioinformatic tools available to interpret the results.
268 ne marrow transplant recipients, and we used bioinformatic tools to evaluate protein abundance and fu
271 uencing technologies, and highlight relevant bioinformatics tools and pipelines to predict the presen
272 addition, we provide a review of some common bioinformatics tools and procedures used for pathogen di
280 rn genomic era, scientists without extensive bioinformatic training need to apply high-power computat
281 es in a single infrastructure across Europe; bioinformatics training is central to its strategy, whic
282 an evidence-based approach for strengthening bioinformatics training programmes across Europe, the EL
286 ing isotope labelling, mass spectrometry and bioinformatics, we calculate turnover rates of individua
296 ollections, services that streamline complex bioinformatic workflows and command-line tools for bulk
298 review, we summarize the most common NGS and bioinformatics workflows in the context of infectious di
300 s and publishes analyses using Galaxy, leads bioinformatics workshops that introduce and use Galaxy,