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1 n Drosophila using wing-vein patterning as a biological assay.
2 lied to 800 000 compounds identified 153 for biological assay.
3 he compounds will be active or inactive in a biological assay.
4 hetic L-DKP insulin was fully active in this biological assay.
5 lization, microbatch chemical reactions, and biological assays.
6 ling, computation-based virtual screens, and biological assays.
7 a and thus is applicable to a wider range of biological assays.
8 erpreting the effects of PPIase mutations in biological assays.
9 ined almost complete activity in preliminary biological assays.
10 ufficient quantities for crystallization and biological assays.
11 at may be useful for fluorescence-based cell biological assays.
12 ules and have evaluated them in a battery of biological assays.
13 oses significant challenges for contemporary biological assays.
14 to optimize them for the robust execution of biological assays.
15 potency of five common KD mutants in various biological assays.
16 nalyses and confirmed by RT-PCR analyses and biological assays.
17 /mL at pH 7.4), was further characterized in biological assays.
18 ivergent types of droplet-based chemical and biological assays.
19 that may translate into clinically relevant biological assays.
20 nds were selected and tested for activity in biological assays.
21 useful analytical platform for a variety of biological assays.
22 by time-consuming microscopic, chemical, and biological assays.
23 fect HDAC1 activity in a number of surrogate biological assays.
24 FTIs and their potencies in biochemical and biological assays.
25 little effect on tyrosine phosphorylation or biological assays.
26 nd the yield was determined via chemical and biological assays.
27 studies were confirmed later by traditional biological assays.
28 (e.g., p21) by using conventional molecular-biological assays.
29 icles (PRPs) as optical reporters in typical biological assays.
30 zes the activity of TGF-beta in two separate biological assays.
31 unting for the behavior of these proteins in biological assays.
32 e effect of each mutation in biochemical and biological assays.
33 sult, we chemically synthesized 13-LAHLA for biological assays.
34 xperiments and further supported by in vitro biological assays.
35 y transmission electron microscopy (TEM) and biological assays.
36 ging, which greatly facilitates their use in biological assays.
37 he observation of their combined response in biological assays.
38 method in comparison to classical molecular biological assays.
39 that combine laboratory evolution with cell biological assays.
40 d macrolides' structure-function activity in biological assays.
41 ications of disease association and relevant biological assays.
42 with a greater loss of viability observed in biological assays.
43 icrofluidic systems for performing multistep biological assays.
44 ation downstream-two important functions for biological assays.
45 in cytotoxicity was confirmed by a series of biological assays.
46 approach has broad applicability to diverse biological assays.
47 broad ranges of high-throughput chemical and biological assays.
48 d, which is applicable to relatively complex biological assays.
49 rrangement by employing biochemical and cell biological assays.
50 oach combining label-free visualization with biological assays.
51 diagnostics, high-throughput screening, and biological assays.
52 d time, offering advantages over traditional biological assays.
53 arget, validated by detailed biochemical and biological assays.
54 ing of biological reagents for surface-based biological assays.
55 lity of this photocaging strategy to execute biological assays.
56 the functionality of parental antibodies in biological assays.
57 olumes is an essential process step for most biological assays.
58 nthesis, which was subsequently confirmed by biological assays.
59 g a variety of immunological, proteomic, and biological assays.
60 photometry for readout of fluorescence-based biological assays.
61 aling in multiple cell-based biochemical and biological assays.
62 a solvent for in vivo administration and in biological assays.
63 this with biochemical measurements and cell biological assays.
64 and prolonged duration of action in in vitro biological assays.
65 n antigen mimics, as we have demonstrated by biological assays.
66 inting or patterning, chemical reactions and biological assays.
67 s easy coupling with conventional downstream biological assays.
68 activities compared with 6-DHSG in multiple biological assays.
69 f a chemical library, followed by cell-based biological assays.
70 by flow cytometry analysis and in vitro cell biological assays.
71 plex functional surfaces for high throughput biological assays.
72 try (CCMS) and were confirmed by independent biological assays.
73 Products were desilylated for biological assays.
74 ened for binding in a series of 26 different biological assays; 7-IBVM (14) exhibited affinity only f
75 o identify compounds that may interfere with biological assays, allowing their removal from screening
76 h syphilis point prevalence data measured by biological assay among MSM (defined as people who were a
78 lectron donor was confirmed by both the disk biological assay and by reversed-phase HPLC analysis of
82 ges compared with traditional biochemical or biological assays and can impact the new way of high-thr
83 ination of polymer and analytical chemistry, biological assays and computational modelling has been u
84 rganic compounds represent prerequisites for biological assays and for respective applications as pha
86 servations and results from binding and cell biological assays and molecular dynamics simulations sho
90 evice and method may facilitate quantitative biological assays and spur the development of the next g
91 for EGF receptor binding, and recognition in biological assays and Western blots by two HB-EGF antise
92 uencing (RNA-seq) is a common and widespread biological assay, and an increasing amount of data is ge
93 Enzyme-linked immunosorbent assay (ELISA), biological assay, and flow cytometry studies confirmed t
94 ed nicotinamide riboside was detected with a biological assay, and intracellular levels of nicotinami
95 he isolation of the authentic e-antigen, its biological assay, and its stabilization as an immune com
96 testing theory, operating characteristics of biological assays, and a model of viral dynamics during
98 environments for cells, immune barriers, new biological assays, and self-assembly of ordered thick me
99 s based on calibration models common to most biological assays, and the resulting chip-specific param
100 ompound-buffer solutions used in the various biological assays are quantitated by LC/UV/CLND to deter
102 M(1) methyl glycoside has been submitted for biological assays as potential ligands for bacterial and
104 ement in the detection of dopamine levels in biological assays at low femtomolar concentrations.
105 s approach, we demonstrate a high-throughput biological assay based on fluorescence resonance energy
107 promising for quantification of chemical and biological assays based on adsorbate-induced ordering tr
109 ds should be studied using several different biological assays before being recommended to the genera
111 probes for the development of ultrasensitive biological assays, cell imaging, or studies of single mo
118 the pyrrolotriazine-4-one series in in vitro biological assays correlated with the magnitude of the t
124 bels, extracts were investigated in specific biological assays, displaying interesting vasorelaxant p
129 (50) = 19 muM), surprisingly, an independent biological assay for compound 13m revealed its antiproli
135 These 20 clones were evaluated in several biological assays for phenotypes associated with particu
136 inant Lewy pathology, as the availability of biological assays for this pathology has sparked new int
137 possibility of clinical in vitro cell based biological assays for various pulmonary diseases such as
141 ve inhibitors of wild-type HIV-1 protease in biological assays having Kis of 0.31-0.35 nM for 9, 0.16
142 ased parallelism of many common functions in biological assays; however, development of a practical t
143 The major modules for realizing molecular biological assays in a micro-total analysis system (muTA
144 tide microarray technology and by performing biological assays in asexual-stage Plasmodium falciparum
146 of advanced melanoma, there are no standard biological assays in clinical usage that can predict met
148 module, which allows a sensitive readout of biological assays in point-of-care (POC) tests, is prese
151 acterized by a range of biochemical and cell biological assays, including a novel high-throughput-scr
153 deep phenotyping, gene filter algorithms and biological assays increased diagnostic yield of exome se
156 e integration of information from a range of biological assays into a single conceptual framework.
157 ng expression of the genes in an independent biological assay involving mouse calvaria (skull bone) p
159 ries datasets generated with high-throughput biological assays, measurements such as gene expression
160 tive discusses CFTR structure and mutations, biological assays, medicinal chemistry research in ident
161 ensued, involving the design, synthesis, and biological assay of analogues designed to address early
163 ning and queries from the patent literature, biological assays of 308 selected compounds (representin
167 econdary and tertiary structure analyses and biological assays of the released proteins showed that e
171 goal would be to use genetic sequence and/or biological assays of viral traits to identify those non-
176 this indexing approach to other chemical and biological assays performed on a microfluidic chip.
177 gmenting agents relied almost exclusively on biological assays performed using mushroom tyrosinase (a
179 nds from microbial sources and a reliance on biological assays rather than direct binding to monitor
180 nds from microbial sources and a reliance on biological assays, rather than direct binding, to monito
182 ation mutagenesis--coupled to an appropriate biological assay--represents a fundamental means of achi
187 aracterization of these iridoid analogues in biological assays revealed novel small-molecule inhibito
191 pounds that did not require purification for biological assay screening, thus reducing experimental t
192 similarity in performance for a given set of biological assays should help prioritize synthesis decis
196 e mimetics to be selective TrkC ligands, and biological assays showed one mimetic to be an antagonist
199 nities for sophisticated and high-throughput biological assays such as cell sorting, rare cell detect
200 tion that allows implementation of different biological assays such as cell tracking or ancestry reco
202 isothermal titration calorimetry (ITC), and biological assays, such as imaging and actin binding.
203 ully extend our photothermal system to other biological assays, such as isothermal nucleic acid ampli
206 of measurements derived from cells and other biological assay systems treated with small molecules.
207 f robotics and automation, together with new biological assay technologies (e.g., homogeneous time re
208 lity of these measurements is dependent on a biological assay that has not been well standardized bet
209 a conformational variance was tested using a biological assay that showed that the hCG-alpha-hCG-beta
210 ptimized compound, NT-7-16, was evaluated in biological assays that confirm that it has potent activi
211 ances parallel with the development of novel biological assays that enabled the ex vivo identificatio
215 nsor based screening method and the in vitro biological assay, the compounds 9 and 11 (propyl and ben
220 e choice of displacement radioligand in each biological assay, their CoMFA StDevCoeff contour plots r
222 limited, we combined molecular modeling with biological assays to ascertain how modifications of phos
223 nts recent progress in using high-throughput biological assays to decipher aberrant pathways and netw
224 es-bis(2-carbamoylaryl)phenyl diselenides-in biological assays to evaluate their anti-SARS-CoV-2 acti
228 e combined biophysical characterization with biological assays to probe HD6 structure and function.
229 ng modalities alongside biochemical and cell biological assays to show that CX-5461 exerts its primar
230 rocessing, we performed biochemical and cell biological assays to study the properties of the mutant.
233 ection of SuFExable compounds toward various biological assays unexpectedly revealed a selective and
236 y and tertiary structure analyses as well as biological assays using single molecule analyses and qua
237 inhibitors in secondary in vitro and in vivo biological assays using three OvCa cell lines: HeyA8, SK
243 orithms, AlphaFold3 structural modeling, and biological assays, we identified multiple MCMV and human
244 n how stereochemistry affects performance in biological assays, we prepared a disaccharide library co
245 techniques and a well-characterized array of biological assays, we prepared original modifications to
246 ombination of single-cell RNA sequencing and biological assays, we reveal distinct transcriptional, p
247 and by combining biophysical techniques and biological assays, we show for the first time that these
248 eted metabolomics analyses combined in vitro biological assays were adopted to investigate the chemic
252 determine the impact of NKA on DAR function, biological assays were conducted with NKA and DARs co-ex
254 ter than (-)-thiocolchicione (2a) in all the biological assays were three (-)-aS,7S optically pure en
255 fulness of these Al-based substrates in many biological assays where high concentration of salts are
258 tegrates an innovative high-throughput proxy biological assay, which generates billions of cyclic pep
261 inhibit NF-kappaB driven transcription in a biological assay with a human reporter cell line; and di