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1 ethods to tease out imperfections in a given biological model.
2 tivated RAW 264.7 macrophages, selected as a biological model.
3 lation of Hif1a and Vegfa expression in this biological model.
4 agreement with previous results on the same biological model.
5 ry environment, they become less relevant as biological models.
6 the elucidation of gene function in numerous biological models.
7 both effectors and regulators of disease in biological models.
8 ity can be generalized to a broader range of biological models.
9 cteristics that cannot be linked to specific biological models.
10 and analysis that is customizable to various biological models.
11 thods and assess their value in some typical biological models.
12 ng of stripes and their function in numerous biological models.
13 hereinafter referred to as spheroids) are 3D biological models.
14 ove it is calibrated in a range of realistic biological models.
15 can derive actionable insights from complex biological models.
16 examine here their phototoxicity in relevant biological models.
17 for the scientific community to generate new biological models.
18 ificance and in providing more interpretable biological models.
19 rts using synthetic H2 S donors in different biological models.
20 ion integration environment for quantitative biological models.
21 pproach will have much wider applications in biological modeling.
22 otivation for leveraging qualitative data in biological modeling.
23 imary cells for therapeutic applications and biological modeling.
24 used in conjunction with other techniques of biological modeling.
25 the olfactory system an important system for biological modelling.
26 xt statements to create, import, and combine biological models, allowing complex models to be built f
27 can create a meta-model of a simulation of a biological model and link that meta-model to experiment
28 is often argued that this is not a realistic biological model and that epistasis (that is, the statis
29 his review, we discuss the theory underlying biological modeling and the process of producing a valua
30 proved by efficiently combining clinical and biological models and by broadening the risk spectrum to
31 nome sequencing, proteomics, patient-derived biological models and computer-based systems biology sim
33 of very large, complex, multimodal data into biological models and mechanisms represents a considerab
34 research, being applicable across a range of biological models and not requiring genetic engineering.
36 It serves to aid the construction of cell biological models and the generation of simulations from
37 rived xenografts (PDXs), partially humanized biological models, and HER2-targeted imaging technologie
38 knowledge gaps, further inform refinement of biological models, and support new experimental and syst
44 ygen radical absorbance capacity (ORAC), and biological model as 2,2'-azobis (2-aminopropane) dihydro
46 es can modulate tau aggregation in the slice biological model at concentrations well below those asso
50 ubstrates of proteolytic enzymes in relevant biological models, both historical and focusing on state
51 mbrane machinery distinct from existing cell biological models but comparable with other free-living
52 d SMLM imaging to a broad range of available biological models, but also present unique insights into
53 ents and trace metals at basal levels in two biological models, cells of Chlamydomonas reinhardtii an
60 r versatile approach is adaptable to various biological models, facilitating its broad application an
61 a useful tool that adapts to the underlying biological model for a disease by weighting appropriatel
62 erefore, developing an accurate and powerful biological model for bipolar disorder has been a challen
63 n the approach could serve as an explanatory biological model for development and drug treatment expe
71 aken together, these findings provide a cell biological model for the role of this metallochaperone u
74 e association studies and exploration of new biological models for allelic exclusion in the human gen
75 of known comorbidities, providing plausible biological models for such co-occurrences and effectivel
76 uently, CPGs have been suggested as valuable biological models for understanding of microcircuit dyna
80 igenic) stimulation in a multistate leukemia biological model (i.e., chronic lymphocytic leukemia).
82 her, the exploration of OncoPPi led to a new biological model in which MKK3 operates by two distinct
83 els with few free parameters to more complex biological models in humans lies in constraining the mor
84 time and its activity was studied in several biological models including transiently or stably transf
85 g of nanotopological changes in a variety of biological models, including extracellular matrix (ECM)
91 forming differential sensitivity analysis of biological models, it can be difficult to determine whic
92 climate-driven statistical, and mechanistic biological models, little work has been done to understa
94 review, we distinguish between two types of biological models--mathematical and computational--which
95 ogically realistic stochastic models to test biological models more stringently and make predictions
96 g idea is that pregnancy represents a unique biological model of a naturally shared circulatory syste
99 Taken together, these data provide a cell biological model of SOD1 biosynthesis that is consistent
100 iew, we first briefly review theoretical and biological models of addiction and then describe existin
103 that 1) redundant pathways are prevalent in biological models of biochemical regulation, 2) the effe
104 o how wealth and socioeconomic status affect biological models of dementia, highlighting the biologic
105 t physical oceanographic models coupled with biological models of infectious agents can characterize
106 sted using the FRAP and DPPH assays, and two biological models of lipid oxidation (activity in preven
107 tially present an overview, which focuses on biological models of lymphatic networks within the breas
113 ed phenotyping will help build more specific biological models of variance in learning processes and
114 ing across multiple length scales, involving biological models of varying complexity, from cell compo
115 esearchers to quickly develop and simulate a biological model on a desktop or laptop, which can then
116 ns of simplified systems that can be used in biological models, or in the creation of advanced respon
117 ut direct measurements from individual small biological model organisms such as C. elegans or isolate
118 the effects of changing various physical and biological model parameters on the developing vascular a
119 alysis can provide chemical-level answers to biological model phenotypic responses as a rapid and cos
121 ulia libraries, and how existing open-source biological modeling projects have extended its intermedi
123 igations comparing and contrasting different biological model scenarios and parameter variations.
124 ion of chemicals or drugs and has influenced biological model selection, concentration range, study d
126 re of CLINKs enable the creation of advanced biological models such as connected neural circuits and
128 e response in each organ assessed for all of biological models surveyed to date; however, the specifi
131 typic cortical cultures from rat brains as a biological model system, in which spontaneous neuronal a
133 The freshwater polyp Hydra is a popular biological model system; however, we still do not unders
134 profiling methods and three-dimensional (3D) biological model systems can potentially provide complex
135 age in the nucleus, has provided very useful biological model systems for the study of the function o
136 tions encompassed chemical, biochemical, and biological model systems generating C-centered radicals.
137 nt and regeneration is hampered by a lack of biological model systems that recapitulate key aspects o
138 of such a process benefits from appropriate biological model systems that reveal how and why certain
140 the key functional capabilities of important biological model systems while abstracting away from the
141 sing ongoing efforts and challenges to mimic biological model systems, with a particular focus on art
143 odel is translated directly into a plausible biological model testable by single-particle tracking.
145 help guide the choices made when developing biological models that aim to characterize spatial-tempo
146 ssue, to the development of disease-specific biological models that recapitulate disease manifestatio
148 e in resources-from atlases and databases to biological models-that is progressively lifting the curt
150 hology, consistent with other MDRS-deficient biological models, thus providing a framework for the en
155 s may produce a more robust and standardised biological model to perform accurate clinical studies.
156 nitiating cells (MICs), we develop a systems biological model to reveal the dynamic regulations by in
157 nitiating cells (MICs), we develop a systems biological model to reveal the dynamic regulations by in
158 simple procedure (called varphi ) to reduce biological models to functional submodules, using statis
159 stituted an accessible, easily usable set of biological models to investigate cancer biology and expl
160 llular systems, demonstrating the breadth of biological models to which this combination of technique
161 ntrolling signal transduction; (ii) evolving biological modeling tools describing cellular circuits a
164 city based on the assay results from all the biological models used in this study, whereas S-TiO2 was
166 tion with experimental data and diagrammatic biological models via the common underlying ALFA represe
167 Relative absorption, in chickens as the biological model, was determined by evaluating growth an
169 Using patient samples and orthotopic PDAC biological models, we showed that radiotherapy increased
171 els to cooperatively drive computational and biological modeling, which together could eventually lea
172 icacy compared to PCFs, across the different biological models, which was attributed to its drainage
173 The zebrafish embryo is a highly interesting biological model with applications in different scientif
176 study integrates high-resolution thermal and biological modeling with techno-economic analysis and li
177 ol provides practitioners and researchers in biological modelling with a one-stop guide that is at th