ライフサイエンスコーパス: biological significance

1 to repair in vivo, which may indicate their biological significance.

2 converted to B-norbenzomorphan analogues of biological significance.

3 inable myocyte-generating progenitor cell of biological significance.

4 ed that these biochemical differences have a biological significance.

5 These variations might have potential biological significance.

6 Both genes have essential, differing biological significance.

7 anking genes based on statistical as well as biological significance.

8 to extract co-expressed modules having high biological significance.

9 ntly ubiquitinated substrates with different biological significance.

10 r mitochondrial function, underscoring their biological significance.

11 dictions for the newly found genes with high biological significance.

12 much attention due to their large number and biological significance.

13 nts often have small effects without obvious biological significance.

14 PRR5 rs3213550 was also selected based on biological significance.

15 stably inherited methylation variants are of biological significance.

16 stinguish levels of different prognostic and biological significance.

17 RNAP) and RNAs] and critically analyze their biological significance.

18 n termination for RNAPII and demonstrate its biological significance.

19 etailed analysis to enable interpretation of biological significance.

20 erization reactions, and are thus of immense biological significance.

21 ylation is essential to accurately interpret biological significance.

22 is locus is a prerequisite to understand its biological significance.

23 contain nonsynonymous mutations of potential biological significance.

24 ally identify protein conformers with likely biological significance.

25 of the canonical pocket that may indicate a biological significance.

26 nd often does represent natural variation of biological significance.

27 single RNA limits our understanding of their biological significance.

28 together by junctional molecules of unknown biological significance.

29 nd efficient stabilization of Tel22 may bear biological significance.

30 ses, eQTLs and CTCF motifs, supporting their biological significance.

31 lected from >35 metabolic pathways of strong biological significance.

32 od for the study of noncovalent complexes of biological significance.

33 es as well as drug targets, indicating their biological significance.

34 s were applied for functional annotation and biological significance.

35 by most cells, were not considered to be of biological significance.

36 class of natural alkaloid analogues of high biological significance.

37 dentifying differential genomic regions with biological significance.

38 structural probing of proteins are of great biological significance.

39 f different ancestry, casting doubt on their biological significance.

40 sis on GSDMD and its mechanism of action and biological significance.

41 ubgroups and characterise their clinical and biological significance.

42 ese numbers, limiting understanding of their biological significance.

43 dose-dependent response against enzymes with biological significance (alpha-glucosidase, acetylcholin

44 or plant breeding, as well as understand its biological significance, analytical approaches have been

45 lice variants, VLDLRI and VLDLRII, but their biological significance and distinction are unknown.

46 A discussion follows on their possible biological significance and effect on mosquito vector co

47 olyphenols is important for evaluating their biological significance and efficacy as functional food

48 a somehow fragmented picture of the possible biological significance and evolution of SL trans-splici

49 In this study, we investigated the biological significance and molecular mechanism of this

50 anged tooth morphology in humans, its direct biological significance and potential adaptive role rema

51 The biological significance and potential clinical applicati

52 However, the biological significance and potential effects of the mic

53 owing intracellular expression; however, the biological significance and prevalence of CP-delta remai

54 The biological significance and prognostic capacity of this

55 novel and far-reaching discoveries that link biological significance and the bacterial epigenome.

56 However, the biological significance and the in vivo relevance of the

57 These findings collectively highlight the biological significance and translational implication of

58 To understand its biological significance and underlying mechanisms, measu

59 tion, MFR also obtains the results with more biological significances and higher average prediction a

60 -order chromatin in mammalian cells, but its biological significances and molecular mechanisms remain

61 for patients, but little is known about its biological significance, and animal models are lacking.

62 mportant considerations for evaluating their biological significance as cancer drivers.

63 e euphyllophytes, and their evolutionary and biological significance as well as their transposition m

64 mTOR folate sensing may have broad biological significance because of the critical role of

65 which include its discovery, structure, and biological significance both in benign and malignant con

66 d sulfoxidation and consider their potential biological significance by evaluating their stoichiometr

67 Despite wide biological significance, delineating filopodia function

68 and RNAlater, 21% of 219 genes of potential biological significance do not correlate in expression.

69 downstream of BRAF(V600E) has functional and biological significance, driving proliferation, invasion

70 The biological significance for mitochondrial cristae has no

71 tiation, suggesting a paracrine or autocrine biological significance for the adipocyte-derived 27HC.

72 This work provides insight into the biological significance for the complex array of hydroly

73 umbers of preformed nucleocapsids, but their biological significance has been debated, and they have

74 he most conserved region of the protein, its biological significance has not been elucidated.

75 ural proteins of the epidermis; however, its biological significance has remained elusive.

76 nal modifier discovered a decade ago but its biological significance has remained mostly unknown.

77 eral of its reported mutations with probable biological significance have not been accomplished enoug

78 In spite of their biological significance, however, methods to discover UB

79 Besides their yet to be clarified biological significance, i-motif nanowires may qualify a

80 nthesize a wide range of organophosphates of biological significance in a deep eutectic solvent (2:1

81 -transgenic mice would allow us to study its biological significance in a tractable animal model of h

82 the PTEN gene in endometrioid carcinoma, its biological significance in BC invasion has been poorly e

83 ospho-regulation of Ajuba in mitosis and its biological significance in cancer.

84 evel between Hedgehog signaling and AKT with biological significance in DLBCL.

85 nzofuran, indoline, and chroman skeletons of biological significance in good to excellent yields; the

86 tivation in cholangiocarcinoma, although its biological significance in initiating and promoting tumo

87 discuss theories of imprinting evolution and biological significance in light of recent findings.

88 siological principles of this branch and its biological significance in stress response.

89 (DNICs) are organometallic-like compounds of biological significance in that they appear in vivo as p

90 with schizophrenia risk, establishing their biological significance is a priority.

91 However, the exploration of RSSH biological significance is challenging due to their inst

92 The biological significance is further substantiated by the

93 volves large contortions of the nucleus, but biological significance is largely unclear.

94 on occurs frequently in plant cells, but its biological significance is poorly understood because mut

95 ndant in several mammalian cell types, their biological significance is sparsely characterized.

96 are activated intracellularly, although the biological significance is unclear.

97 is conserved across eukaryotes, although its biological significance is unknown.

98 Their global biological significance is unproven and remains controve

99 Despite its biological significance, knowledge of Pol beta activitie

100 Here, we identified and characterized the biological significance of a novel tyrosine kinase that

101 ates an effective approach to appreciate the biological significance of a small effect.

102 hrough the cell cycle; (3) insights into the biological significance of A-DNA as evidenced by an inte

103 These results support the biological significance of actin catch bonds, as they co

104 The results highlight the biological significance of alternative Bdnf transcripts

105 ibody to see widespread use in analyzing the biological significance of arginine phosphorylation.

106 ity in the ventral striatum to represent the biological significance of associative information in th

107 The biological significance of BR-mediated changes in hypoco

108 The biological significance of C5a receptor [(C5aR)2/C5L2],

109 nologies have highlighted the prevalence and biological significance of cellular heterogeneity.

110 sulfite sequencing (BS-seq) to determine the biological significance of CFK1-mediated DRM2 degradatio

111 The biological significance of charge complementarity in the

112 The biological significance of conserved replication timing

113 epithelium, thus opening the possibility of biological significance of counteracting demethylases.

114 The biological significance of COUP-TFII in prostate carcino

115 To explore the biological significance of crosstalk between Toll-like r

116 carbohydrate active enzyme families and the biological significance of cryptic metabolic pathways, s

117 However, the pathogenesis and biological significance of CSLCs in PC has not been well

118 with a particular focus on understanding the biological significance of CTCs, and summarizes emerging

119 Here, we show clinical and biological significance of CXCR6-CXCL16 and ADAM10 in Ov

120 time-course experiments and to highlight the biological significance of data with regard to the Gene

121 This study also underscores the biological significance of deubiquitinase activity in MS

122 Currently, the biological significance of Dmp1-cyclin D1 interplay in b

123 temporal features, we know little about the biological significance of each temporal component.

124 s study sought to determine the clinical and biological significance of elevated cardiac troponin T (

125 erein, we discuss new findings regarding the biological significance of enamine and imine production

126 challenge in epigenetics is to determine the biological significance of epigenetic variation among in

127 essing these phenomena, but interpreting the biological significance of epistasis and pleiotropy is o

128 , including PIN5, we define a long-neglected biological significance of ER-based auxin regulation.

129 We review the current understanding and biological significance of ERAD-mediated regulation of l

130 However, the biological significance of excess endolysosomal Cu accum

131 The biological significance of extracellular vesicles (EVs)

132 Biological significance of Fc glycans has been extensive

133 asured, resulting in confusion regarding the biological significance of flow-induced ciliary mechanot

134 n in microbial and vertebrate organisms, the biological significance of GC content diversity in plant

135 Here, to assess the biological significance of genetic diversity acquired th

136 The biological significance of genomic features is often con

137 be sequenced to further understanding of the biological significance of genomic heterogeneity in comp

138 Seq2pathway associates the biological significance of genomic loci with their targe

139 These findings reveal the biological significance of HA glycosylation and therapeu

140 Unraveling the biogenesis and biological significance of heterogenetic RNA expression

141 (A)C family, and afford new insight into the biological significance of histidine brace-mediated copp

142 ever as a model system for understanding the biological significance of human genetic variation and f

143 ods for analysis, underlying mechanisms, and biological significance of hypertranscription.

144 L2 are associated with Perlman syndrome, the biological significance of impaired DMD is obscure and p

145 cuss the major progress in understanding the biological significance of Itch-promoted protein ubiquit

146 erspective of drug discovery, the nature and biological significance of its interactome remain largel

147 However, the biological significance of Jab1 activity in response to

148 of the cell cycle, but the mechanism and the biological significance of kinetochore clustering are un

149 These findings highlight the biological significance of lysine fatty acylation and si

150 rginine are well-established, the extent and biological significance of lysine phosphorylation has re

151 resource for future studies of function and biological significance of m5C in mRNA in mammals.

152 study, we sought to investigate further the biological significance of MA trimerization by isolating

153 This study aims to clarify the clinical and biological significance of metastasis-associated long no

154 the leaf and kernel tissues, pointing to the biological significance of methylation variation.

155 he goal of this study was to demonstrate the biological significance of MgrA regulation of capsule an

156 These data demonstrate the mechanism and biological significance of mHTT-mediated inhibition of m

157 The biological significance of minimal absent words has been

158 Further we elucidated the biological significance of miR-23b in bladder cancer.

159 The biological significance of miRNAs present in the extrace

160 The present data are the first to show the biological significance of mitochondrial Mb as a potenti

161 reonine aspartase 1 (taspase1); however, the biological significance of MLL1 cleavage by this endopep

162 However, the biological significance of mycobactins in the growth of

163 nsferase 1 (PMAT1), to better understand the biological significance of NAE 12:0-induced gene express

164 The biological significance of NETs is just beginning to be

165 This article discusses the biological significance of network motifs, the motivatio

166 in vascular tissue called into question the biological significance of NO formation by purified ALDH

167 well-known to regulate gene expression, the biological significance of nonhistone methylation is poo

168 The present study examined the biological significance of notes of the male advertiseme

169 To investigate the biological significance of OPG-HS interaction in bone re

170 population compartmental mask, corroborating biological significance of our annotation of the chromat

171 icrobiome Project, a close evaluation of the biological significance of our findings confirms existin

172 We discuss the biological significance of our observation in relation t

173 uce oxalic acid levels and to understand the biological significance of OXDC in crop plants have met

174 interact with host factors for function, the biological significance of pathogenic noncoding RNAs in

175 The biological significance of PB2-S1 to the replication and

176 tively, these studies further underscore the biological significance of Perforin-2 and elucidate crit

177 This study investigates the biological significance of perinuclear positioning for h

178 The method generates the magnitude and the biological significance of personal deregulated pathways

179 data are unique in providing evidence of the biological significance of protein O-mannosylation in my

180 s that will advance our understanding of the biological significance of RBPs in plant developmental a

181 Finally, the biological significance of repression differences was de

182 Despite the biological significance of RNase L, the RNAs cleaved by

183 In particular, we explore the biological significance of shadow prices in a constraint

184 lines, and Epstein-Barr virus; however, the biological significance of sisRNAs remains poorly unders

185 The biological significance of SSEA-4/FKBP4 interaction was

186 iding toxicological studies to determine the biological significance of such exposures.

187 An accepted theory explaining the biological significance of such non-uniform codon select

188 -specific m(6)A patterns, and we discuss the biological significance of such regulation.

189 However, the biological significance of such regulators in M. avium s

190 To understand the biological significance of such sequence heterogeneity,

191 Although the biological significance of such vesicles was initially d

192 Taken together, our observations explain the biological significance of TET oligomerization and sugge

193 To determine the biological significance of Tf1 integration, we took adva

194 hroughout all growth phases in S. aureus The biological significance of the 100S ribosome is poorly u

195 The putative biological significance of the centrifugal antennal-lobe

196 These findings reveal the biological significance of the CHRNA2 pathway in beige f

197 Our understanding of the biological significance of the complex architecture of t

198 The theory lets us address the biological significance of the constrained joint and pro

199 ngthened proteins were also used to test the biological significance of the crystal structure.

200 The biological significance of the desmoplastic tumor microe

201 The biological significance of the desmoplastic tumor microe

202 The biological significance of the DHTKD1-encoded 2-oxoadipa

203 Although the biological significance of the DNA-O-glycosidase reactio

204 ermine the individual proteolytic events and biological significance of the ectodomain shedding in th

205 In this study, we have established the biological significance of the HIV-1 RT-IN interaction d

206 ctiveness of our methods is validated by the biological significance of the identified differential n

207 The biological significance of the IL-21/IL-21R system in hu

208 rovides the starting point for revealing the biological significance of the interaction of IL-10 with

209 proteins are known to be acetylated, but the biological significance of the majority of these events

210 e is a crucial step toward understanding the biological significance of the modification.

211 cond attempt to understand the structure and biological significance of the nucleocapsid.

212 To determine the biological significance of the p53-Rbm38 loop, we showed

213 We validate the biological significance of the pol-II promoter activity

214 gorithms in terms of prediction accuracy and biological significance of the predictions.

215 f galectin-3 in neutrophil migration and the biological significance of the rapid migration of neutro

216 The biological significance of the reversible inhibition of

217 pread of the mutant virus, strengthening the biological significance of the RFC complex as a host res

218 To determine the biological significance of the RT-IN interaction during

219 now provide the basis for understanding the biological significance of the stereochemical dependence

220 Moreover, the biological significance of the synthesized benzothiadiaz

221 These studies support the biological significance of the triangular trimer assembl

222 Despite the biological significance of the UPR to the life of the or

223 However, the expression and biological significance of the VEGFC/VEGF receptor (VEGF

224 enes of prognostic relevance, supporting the biological significance of the work.

225 The biological significance of these amino acid changes can

226 The biological significance of these differences and whether

227 We further tested the biological significance of these findings in a model of

228 To examine the biological significance of these findings in the context

229 The biological significance of these findings was confirmed

230 equencing will provide the tools to test the biological significance of these gene regulatory network

231 we found additional evidence to support the biological significance of these gene-gene associations,

232 The biological significance of these genes is evaluated usin

233 Despite the well-established biological significance of these glycans, questions rega

234 However, the biological significance of these hidden polypeptides is

235 The biological significance of these infections is unknown.O

236 and PA directly target RIG-I, but the exact biological significance of these interactions in the rep

237 We discuss the biological significance of these new findings and their

238 The biological significance of these observations was evalua

239 the involvement of microRNAs in cancer, the biological significance of these phenotypic and genotypi

240 her genomic studies are needed to assess the biological significance of these results.

241 To evaluate the biological significance of these sites, we tested for as

242 ation of rG4 folding-unfolding underpins the biological significance of these structures in the regul

243 However, the biological significance of these transcriptional repress

244 This absolute conservation is evidence for biological significance of these unique biochemical prop

245 The biological significance of this asymmetrical response in

246 The biological significance of this correlation was corrobor

247 To explore the biological significance of this editing function, we cre

248 plication demonstrate for the first time the biological significance of this family of DNA lesions.

249 To ascertain the biological significance of this hypothesis, we focused o

250 The biological significance of this induction of miR-29b is

251 In this study, we examined the biological significance of this interaction during infec

252 ar FHL1 protein in CHIKV HVD and defined the biological significance of this interaction.

253 known to affect chromatin dynamics, but the biological significance of this interplay is still not c

254 Multiple VEGF-A isoforms exist, but the biological significance of this is unclear.

255 ed into N- and C-terminal fragments, but the biological significance of this is unknown.

256 e circadian clock, but the mechanism and the biological significance of this link have only begun to

257 However, the ecological or biological significance of this metabolite diversity is

258 new and improved gene models and assess the biological significance of this method in Oryza sativa.

259 However, the biological significance of this modification is unknown,

260 o draw any firm conclusions on the potential biological significance of this observation and further

261 However, the biological significance of this organization has been di

262 xia-inducible factor 1 (FIH-1); however, the biological significance of this phenomenon is unclear.

263 The biological significance of this PKCtheta/alphaPIX/Rac 1

264 C) risk that is heightened in women, but the biological significance of this polymorphism has never b

265 HDAC6 as specific deacetylases, showing the biological significance of this post-translational modif

266 To elucidate the biological significance of this proteolytic modification

267 However, the biological significance of this response was unclear.

268 n downstream CaM targets, thus expanding the biological significance of this small regulator of CaM s

269 The biological significance of this step is evident from ble

270 The biological significance of this tRNA nuclear import is n

271 The biological significance of this type of complementation

272 ith a noise trimming approach to predict the biological significance of Tn5 mutations.

273 We tested the biological significance of two amino acid mutations in t

274 The precise origins and the potential biological significance of various forms of miRNA-contai

275 This work furthers understanding of the biological significance of vIL-6 and its unique intracel

276 omogeneous protein crowders, reinforcing the biological significance of weak, nonspecific interaction

277 associated with reduced platelet counts, the biological significance of which has remained elusive.

278 ryos are also photosynthetically active, the biological significance of which remains poorly understo

279 Of biological significance, our analysis reveals an optimal

280 re of genes regulated by macroH2As and their biological significance remain unclear.

281 centrosome behavior is widely conserved, its biological significance remains largely unclear.

282 ycans with minor covalent substituents whose biological significance remains largely unknown.

283 the same protein family, its functional and biological significance remains to be addressed.

284 te in heterogeneous environments whose exact biological significance remains to be unveiled.

285 ted in response to inflammatory signals, its biological significance remains unclear.

286 Despite their biological significance, surprisingly little is known of

287 results are also validated through a proper biological significance test and heatmap plotting.

288 lts are further validated through well-known biological significance test and visualization tool.

289 BIOLOGICAL SIGNIFICANCE: Theobroma grandiflorum and Theo

290 ce projected, it can be difficult to ascribe biological significance to the observed features.

291 localized to conserved molecular regions of biological significance to the virus were enriched for H

292 erging in incremental steps, but attributing biological significance to their G protein signalling fu

293 Our study assigns biological significance to TR variations in the human ge

294 germline, and de novo variants of potential biological significance using publicly available data se

295 North American populations, we studied their biological significance using transgenic mice.

296 To address the biological significance, we generated phospho-deficient

297 To shed light on the potential biological significance, we here adopt a systems approac

298 atistical pipeline to assess statistical and biological significance while managing the multiple test

299 Applied to this protein of biological significance with large inhomogeneous broaden

300 act strongly with several immune proteins of biological significance, with these interactions resulti