ライフサイエンスコーパス: biomolecule

1 od for nanoscale imaging of various types of biomolecule.

2 tical device for ultrasensitive detection of biomolecule.

3 sed as a proxy for the direct interaction of biomolecules.

4 life sciences to understand the kinetics of biomolecules.

5 otopes to the methods used to attach them to biomolecules.

6 ine is the source of all bacterial sulfurous biomolecules.

7 rgeting vectors or surrogates for endogenous biomolecules.

8 or exploring the subcellular organization of biomolecules.

9 nces within and between structurally dynamic biomolecules.

10 a protein's modes of interactions with other biomolecules.

11 -speed and low-noise sensing of a variety of biomolecules.

12 peptides and other membrane-active drugs or biomolecules.

13 of most commonly used phenolic compounds and biomolecules.

14 bout the biological function of the analyzed biomolecules.

15 nts the key step for efficient imprinting of biomolecules.

16 s interact with densely-packed membranes and biomolecules.

17 haracterize micro-to-millisecond dynamics in biomolecules.

18 the subatomic weak force to homochirality in biomolecules.

19 methodologies for cell-specific labeling of biomolecules.

20 ole in the mechanically induced unfolding of biomolecules.

21 onse for generic compounds including complex biomolecules.

22 gths and to encapsulate, protect and release biomolecules.

23 enhanced ability to produce these functional biomolecules.

24 merous studies of organic semiconductors and biomolecules.

25 d for studying the structure and dynamics of biomolecules.

26 orces can be applied to microsphere-tethered biomolecules.

27 rkers to nucleic acid sequences and secreted biomolecules.

28 sure leading to the accumulation of oxidized biomolecules.

29 by endowing light sensitivity to endogenous biomolecules.

30 r fluorescence polarization (FP) analysis of biomolecules.

31 ction as a membrane-anchoring unit for other biomolecules.

32 ing the broad diversity and dynamic range of biomolecules.

33 usive biophysical regime of phase separating biomolecules.

34 interactions between other 2D materials and biomolecules.

35 molecular level, of nonionizing radiation on biomolecules.

36 under aqueous conditions in the presence of biomolecules.

37 amagnetic labels for enhanced NMR studies on biomolecules.

38 fast, accurate and reproducible detection of biomolecules.

39 he highest numbers of D-amino acids in known biomolecules.

40 oidal particles that are macro-aggregates of biomolecules.

41 mi designs to probe mechanical properties of biomolecules.

42 variety of primary ammonium ions, including biomolecules.

43 ely recruiting multiple copies of regulatory biomolecules.

44 e potential to detect COVID-19 viruses based biomolecules.

45 of heparan sulfate and structurally related biomolecules.

46 ection and quantification of a wide range of biomolecules.

47 c lineage markers of the immune system using biomolecules.

48 rous applications in fluorescent labeling of biomolecules.

49 coordinated via locally produced regulatory biomolecules.

50 een proteins, and between proteins and other biomolecules.

51 s well as pharmaceuticals, agrochemicals and biomolecules.

52 s can increase oxidative damage to essential biomolecules, accelerating the rate of ageing.

53 r transmembrane transport of a wide range of biomolecules against concentration gradients.

54 cessful separation and identification of the biomolecules AMP, ATP, and CoA, which are fundamental fo

55 to be broadly utilized for other whole blood biomolecule analyses in POC testing applications.

56 momentum in the field of mass spectrometric biomolecule analysis, including proteomics, glycomics, a

57 etection and diagnostic platforms via single-biomolecule analysis.

58 T between a single fluorophore attached to a biomolecule and many quenchers in a liposome.

59 cal diagnostics, and analytical detection of biomolecules and cellular activities are presented.

60 lized plaque, represents a record of ancient biomolecules and food residues.

61 Biomolecules and functional activity were measured in mi

62 ents, promoted phase partitioning of cardiac biomolecules and fused with stress granules.

63 accounts for the great complexity of larger biomolecules and gives a two-dimensional distribution of

64 made of polysaccharides, proteins, and other biomolecules and have evolved to withstand large amounts

65 the signal generated during translocation of biomolecules and improves the nanopores' efficiency when

66 es in applications for in vitro detection of biomolecules and in vivo imaging of cellular networks.

67 ed selective delivery of a desired number of biomolecules and integration of optical detection techni

68 ection of four classes of CBW agent simulant biomolecules and organisms each representing credible th

69 heir potential for deep tissue activation of biomolecules and phototherapeutics.

70 ven the ubiquity of carbon-hydrogen bonds in biomolecules and polymer backbones, the development of a

71 lar recognition events between 'undruggable' biomolecules and small molecules, and the ability of seq

72 optosis-related pathways, including relevant biomolecules and small-molecule modulators regulating th

73 ting for the characterization of dynamics in biomolecules and soft matter.

74 of dairy buffaloes enhances health-promoting biomolecules and the antioxidant and antineoplastic prop

75 relative abundances of different unlabelled biomolecules and their complexes in mixtures at the sing

76 al device to monitor the dynamic features of biomolecules and their interactions with neighboring mol

77 omolecules detection can be extened to other biomolecules and this type of architecture has the poten

78 applications, primarily preconcentration of biomolecules and water desalination.

79 ach relies on localizing and tracking target biomolecules and/or subcellular organelles labeled with

80 en (N) is used in many of life's fundamental biomolecules, and it is also a participant in environmen

81 ipids are one of the most studied classes of biomolecules, and monitoring lipid distribution and abun

82 uestions that are approachable using ancient biomolecules, and plant research has been a constant, in

83 number of pharmaceuticals, agrochemicals and biomolecules, and play vital roles in the function of th

84 ion for magnetic actuation, encapsulation of biomolecules, and surface functionalization for drug del

85 y clear over the past few decades that these biomolecules are also capable of performing other comple

86 le, enables researchers to determine whether biomolecules are moving alone, as part of a larger compl

87 These biomolecules are now known to support spermatogenesis an

88 Many important biomolecules are present in the tissue milieu in low con

89 , brief events where molecules (particularly biomolecules) are caught in the act of surmounting activ

90 to capture atomically detailed snapshots of biomolecules as they function.

91 often studied with methods requiring labeled biomolecules, as the existing methods utilizing luminesc

92 ical and structural properties of individual biomolecules, as well as their interactions, in a broad

93 Quantitative measurements of biomolecule associations are central to biological under

94 ble approach to enhance specific nanocrystal-biomolecule associations for improving cellular targetin

95 ic potential that can rapidly trap sub-10 nm biomolecules at femtomolar concentrations on demand.

96 or the development of automated detection of biomolecules at the nanoliter scale.

97 rogate microRNA (miRNA) and metabolites, two biomolecules available in blood serum, in order to compr

98 This biomolecule-based strategy can address multiple delivery

99 d higher-order structures of these important biomolecules because incorrect disulfide bond formation

100 re needed, but with many current approaches, biomolecules become entrapped in the endosomes.

101 from raw microscope images to histograms of biomolecule behavior, is a user-adjustable quality thres

102 They can also enhance biomolecules bioavailability and controlled release, at

103 rovide enormous insight into the dynamics of biomolecules, but adequately sampling distributions of s

104 hore-based tools were introduced to specific biomolecules by covalent binding.

105 low-contrast micrographs of frozen hydrated biomolecules by cryo-electron microscopy (cryo-EM) repre

106 sed biosensors allow label-free detection of biomolecules by measuring their intrinsic charges.

107 ancer drugs designed to cleave intracellular biomolecules by O(2) activation.

108 ently labeled streptavidin, a large range of biomolecules can be imaged by the standard ExM procedure

109 ges in the tertiary conformation of adsorbed biomolecules can induce detectable shifts (Deltatheta(r)

110 with the charge density lower than receptor biomolecules can reduce the collective electrical potent

111 Biomolecules can undergo liquid-liquid phase separation

112 lexity at different length scales, mimicking biomolecules, can occur in active-metal clusters and pro

113 erefore can be utilized for the detection of biomolecule carbonylation in various cancer cell lines.

114 The biomolecule cargo is then electrophoretically drawn into

115 ergy conversion and storage, manipulation of biomolecules, catalysis, as well as materials design and

116 As such, biomolecule-clay and polymer-clay interactions are set i

117 To date, both biomolecule-clay and polymer-clay nanocomposite strategi

118 the visualization and tracking of a specific biomolecules, complexes, and cellular compartments with

119 f solid-state nanopores as sensors of target biomolecule concentration.

120 es with the cell volume in order to maintain biomolecule concentrations and cell density.

121 ms biology approach that monitors changes in biomolecule concentrations to diagnose and monitor healt

122 eal simultaneous analysis of small and large biomolecules, confident metabolite annotation, identific

123 Interactions between biomolecules control the processes of life in health and

124 not determine C3 deposition efficiency, the biomolecule corona per se enhances immunoglobulin bindin

125 that poses the dominant physical barrier to biomolecule delivery in plants.

126 Exogenous biomolecule delivery into plants is difficult because th

127 ENGs, it successfully realizes a transdermal biomolecule delivery with an over threefold depth enhanc

128 le doped optical fiber was developed for the biomolecule detection.

129 the sensitivity of devices and its effect on biomolecules detection can be extened to other biomolecu

130 The chemical and structural properties of biomolecules determine their interactions, and thus thei

131 to no oxidization, and high compatibility to biomolecules due to its fluorescence quenching capabilit

132 However, minute size and lack of essential biomolecules (e.g. omega-3 polyunsaturated fatty acids a

133 parable size of nanostructured materials and biomolecules enabled the integration of biological syste

134 et splitting, resulting in the generation of biomolecule-enriched daughter droplets.

135 cation of the preconcentrated plug of target biomolecules, ensuring its overlap with the functionaliz

136 While the connectivity of scaffolds (biomolecules essential for LLPS) dominates the phase lan

137 ntification using generic standards for most biomolecules except proteins and hydrophobic peptides.

138 Biomolecules exhibit a wide range of functions and struc

139 and its potential use in detection of trace biomolecules explored.

140 fered, aqueous conditions in the presence of biomolecules find application in ligation, peptide synth

141 d peptides are two of the most commonly used biomolecules for building self-assembling materials, but

142 archical assembly-is of great importance for biomolecules for the functions of life.

143 Biomolecules form dynamic ensembles of many inter-conver

144 cilitated dissociation," in which competitor biomolecules from solution enhance molecular dissociatio

145 Biomolecules function by adopting multiple conformations

146 nanostructures functionalized with different biomolecules/functional units, imaging smart biomaterial

147 epared via graft-through polymerization from biomolecule functionalized monomers.

148 Imaging of biomolecules guides our understanding of their diverse s

149 ols for sensitive and selective detection of biomolecules has attracted tremendous attention.

150 olecules play in the mechanical unfolding of biomolecules has not yet been fully elucidated.

151 detail, the effects of potassium bromate on biomolecules, human health, environment and various meth

152 rmation to generate complex surfactants with biomolecules (i.e., antibodies) for biosensing applicati

153 ummarize the principle and workflow of small-biomolecule imaging by Raman microscopy.

154 urfaces and allowing their reuse for further biomolecules immobilizations, recycling the functional s

155 apid, sensitive, and real-time monitoring of biomolecules in biologically relevant media such as bloo

156 ction as well as the capability of analyzing biomolecules in both positive and negative ion modes for

157 ethod for studying conformational changes of biomolecules in cells.

158 aluable tools to locate and image functional biomolecules in cells.

159 ic platform to evaluate antibodies and other biomolecules in clinical specimens.

160 Labeling of biomolecules in live eukaryotic cells has been limited b

161 portunities for noninvasive imaging of small biomolecules in living cells, tissues, and organisms.

162 t detailed information about the behavior of biomolecules in living cells.

163 hemistries enable researchers to interrogate biomolecules in living systems.

164 Given the centrality of phosphorylated biomolecules in metabolic, structural, and replicative p

165 The effect of green feed on health-promoting biomolecules in milk was examined in dairy buffaloes.

166 Polysaccharides are the most abundant biomolecules in nature, but are the least understood in

167 Carbohydrates are ubiquitous biomolecules in nature.

168 ensors that continuously measure circulating biomolecules in real time could provide insights into th

169 nvolvement of nonspecific interactions among biomolecules in regulating their biological functions.

170 se findings permit the inclusion of magnetic biomolecules in the CISS field and pave the way to their

171 ovide an integrated view of the abundance of biomolecules in the eukaryotic cell cycle and point to a

172 cedented picture of the structure of neutral biomolecules in the gas phase.

173 utility of bioinspired design and the use of biomolecules in the preparation of high-performance ther

174 measures real-time conformational change of biomolecules in the presence of biological ligands and s

175 ution cryo-ET and structure determination of biomolecules in their native environment.

176 Identifying the spatial distributions of biomolecules in tissue is crucial for understanding inte

177 ctrometry (IMS) allows for direct mapping of biomolecules in tissues.

178 roves chemical detection of lipids and other biomolecules in tissues.

179 However, some acyl-glucuronides react with biomolecules in vivo, which may result in immune-mediate

180 ticles, thereby enabling studies of adsorbed biomolecules in vivo.

181 gnitude that enable the 3D imaging of dilute biomolecules including gases.

182 ibility of i-TIMES technique using different biomolecules including lysozyme, N,N',N"-triacetylchitot

183 n platform for sensitively analyzing various biomolecules including small molecules (adenosine tripho

184 3D structures of biomolecules (including proteins, DNA, RNA, and their co

185 edback-controlled introduction of individual biomolecules, including 70S ribosomes, DNAs and proteins

186 experimental strategies targeting different biomolecules, including DNA (metagenomics), RNA (metatra

187 group plays a key role in the composition of biomolecules, including many clinically approved drugs.

188 tion of clinically relevant disease-specific biomolecules, including nucleic acids, circulating tumor

189 spectrometry imaging of numerous classes of biomolecules, including phospho- and glycolipids in tiss

190 Measurements of very low levels of biomolecules, including proteins and nucleic acids, rema

191 sample conformations and transition paths of biomolecules, including the application described in thi

192 Spider venom biomolecules induced smaller and necrotic xenogeneic GB;

193 g experimentally-determined 3D structures of biomolecules integrated with >40 external data resources

194 ions can dramatically alter the way in which biomolecules interact with other components of the syste

195 n the simplified assumption that also larger biomolecules interactions are homogeneous.

196 ted nano-scale structures containing various biomolecules involved in cell communication and multiple

197 lipid acceptors and whether there are other biomolecules involved in MTTP-mediated lipid transport r

198 t to experimental prebiotic syntheses of key biomolecules is a compelling reason to consider carbonat

199 al results demonstrate how the enrichment of biomolecules is influenced by their size, charge, and co

200 nspecifically interacting proteins and other biomolecules is mostly overlooked.

201 emble of chemically and functionally diverse biomolecules is termed the 'matrixome'.

202 within a protective extracellular matrix of biomolecules, leading to chronic and recurring antibioti

203 rio, leading to the desorption/ionization of biomolecules (lipids, metabolites and proteins).

204 se the degree of inhibition, indicating that biomolecules may contribute to reduced coral calcificati

205 have the highest GB of any small, monomeric biomolecules measured to date and are more basic than ar

206 amed alphaESM, captures the shape of a given biomolecule most economically using alpha shape, a well-

207 Potential inhibitors of a target biomolecule, NAD-dependent deacetylase Sirtuin 1, were i

208 Biomolecules of different sizes migrate toward one side

209 agents that bind tightly and specifically to biomolecules of interest remain essential in the explora

210 he calcined natural oyster shell (CNOS), and biomolecules of the organic matrix extracted from the oy

211 ical energy by integration of photosynthetic biomolecules on electrodes.

212 se and adsorbed corona-phase DNA and protein biomolecules on single-walled carbon nanotubes (SWCNTs).

213 orm to spatially anchor targeting ligands or biomolecules on the surface, while the hollow cylindrica

214 e of imprinted PNE as synthetic receptor for biomolecules, opening new perspectives for this biopolym

215 ction as anchor groups for the attachment of biomolecules or as reversible binding sites for proteins

216 ecular fingerprinting of complex mixtures of biomolecules or organic crystals with markedly enhanced

217 ion of quantum optics with this prototypical biomolecule paves the way for quantum-assisted measureme

218 Biomolecules play key roles in regulating the precipitat

219 control the location of the preconcentrated biomolecule plug to ensure overlap with the sensing regi

220 ontrolling the location of a preconcentrated biomolecule plug.

221 To incorporate phosphate into biomolecules, prebiotic experiments commonly use molar p

222 Concentration-polarization (CP)-based biomolecule preconcentration is highly effective in enha

223 Lipids are biomolecules present in all living organisms that, apart

224 etabolism is essential for normal energy and biomolecule production, and goes awry in many diseases.

225 rbohydrates are a class of large and diverse biomolecules, ranging from a simple monosaccharide to la

226 gral membrane proteins-an important class of biomolecules-remain enormously challenging to access syn

227 icry of the natural hierarchical assembly of biomolecules remains challenging due to the lack of an a

228 triphosphate and its use in the synthesis of biomolecules require enzymes.

229 To function, biomolecules require sufficient specificity of interacti

230 ells, and often external forces applied to a biomolecule result in its unfolding.

231 f DNA-nanoparticle complexes once applied in biomolecule-rich, in vivo environments remains unpredict

232 roach, we show that a previously undescribed biomolecule, S-geranylgeranyl-L-glutathione (GGG), is a

233 es their characteristics like chemotaxis and biomolecule secretion to outperform conventional diagnos

234 r map of O-glycosites in this large class of biomolecules serves as a discovery platform for an impor

235 3D niche stiffness synergizes with WNT7a, a biomolecule shown to control SC symmetric self-renewal d

236 the sensing surface for detecting the target biomolecules, sIgEs to Pru p 3.

237 ting interactions between proteins and other biomolecules solely based on structure remains a challen

238 We show that biomolecules, specifically proteins, provide an intrinsi

239 nal alkynes for bioorthogonal reactions into biomolecules still present limitations in terms of eithe

240 on to DNA sequences, physically handling the biomolecules, storing them and subsequently re-obtaining

241 formation about the mechanical properties of biomolecules such as chromatin fibers.

242 f MOFs, that allows the protection of active biomolecules such as enzymes or the development of antim

243 l to reveal the localization of thousands of biomolecules such as metabolites and lipids in tissue se

244 Natural biomolecules such as peptides and DNA can dynamically se

245 Visualizing the functional interactions of biomolecules such as proteins and nucleic acids is key t

246 Interactions between biomolecules such as proteins underlie most cellular pro

247 cules, from small hydrophobic drugs to large biomolecules such as proteins.

248 of amino acids such as methionine and other biomolecules such as purines, thymidylate, and redox reg

249 entation, greatly improving the detection of biomolecules such as triacylglycerides.

250 emerge from the noise in the partitioning of biomolecules (such as RNAs and proteins) among daughter

251 sion exceeds the speeds of well-known active biomolecules, such as myosin, by several orders of magni

252 ssium bromate has significant effect on food biomolecules, such as starch and protein, as it affects

253 ides a freely available source of sulfur for biomolecule synthesis.

254 onstrated to separate DNA, which is a larger biomolecule than proteins.

255 major drawback for the production of certain biomolecules that are essential for research, pharmaceut

256 We aimed to identify biomolecules that are expressed differentially in human

257 principles determination of the CCS of large biomolecules that can then be used as CCS calibrants.

258 We briefly discuss the biomolecules that maintain the BTB: these provide new in

259 olutionized our understanding of biology and biomolecules, the workflow in preparing for such experim

260 For each biomolecule, this information is shown in the form of a

261 potentially allowing us to recognise further biomolecules thought to be lost during the fossilisation

262 ained for 14 different relevant S-containing biomolecules (three peptides, four proteins, one amino a

263 P), which reacts with the carbonyl moiety of biomolecules through bioorthogonal reaction, therefore c

264 Electrokinetic translocation of biomolecules through solid-state nanopores represents a

265 llow the reaction trajectories of individual biomolecules to be directly observed, eliminating the ef

266 Binding of biomolecules to crystal surfaces is critical for effecti

267 the CNS ranging from the removal of unwanted biomolecules to intercellular communication to the sprea

268 lumina nanotubes that can be used to deliver biomolecules to living cells.

269 been explored for sustained localization of biomolecules to promote in vivo tissue regeneration.

270 embrane-bound vesicles capable of delivering biomolecules to recipient cells and subsequently alterin

271 n reduce data comprising hundreds of altered biomolecules to smaller sets of altered biological 'conc

272 nts, paracrine factors, cytokines, and other biomolecules to support germ cell development.

273 ters to validate the binding of the selected biomolecules to the active site of the co-receptors.

274 The attachment of target biomolecules to the films changes the resistance of the

275 anopore sequencing, in which the delivery of biomolecules towards a nanopore controls the method's th

276 Even though biomolecules typically contain an abundance of easily io

277 Biomolecules undergo motions on the micro-to-millisecond

278 ive investigators control over activation of biomolecules using targeted light irradiation.

279 ure real-time binding of fluorophore-labeled biomolecules, utilizing the SWCNT surface as a fluoresce

280 drimer (TD) nanotrap (NT) to capture various biomolecules via multivalent, hybrid and synergistic int

281 ethods enable the manipulation of individual biomolecules via the application of forces and torques a

282 Biomolecules were fluorescently labeled, and fluorescenc

283 ncer cells continuously secrete inflammatory biomolecules which play significant roles in disease pro

284 mechanisms are relatively limited for small biomolecules, which are equally important participants i

285 ng of the nonspecifically adsorbed salts and biomolecules, while significantly delaying the dissociat

286 RNA is a versatile biomolecule with a broad range of biological functions t

287 nsates that compartmentalize and concentrate biomolecules with distinct physicochemical properties.

288 tting, is a powerful strategy for generating biomolecules with diverse and tailored properties.

289 eins (IDPs) constitute an important class of biomolecules with high flexibility.

290 Fe, Cu and Zn were associated with biomolecules with high molecular mass compounds, such as

291 between these and the efficient sampling of biomolecules with hundreds of thousands of atoms.

292 However, biomolecules with multiple dissociation pathways may hav

293 Ls comprise structurally diverse families of biomolecules with potent bioactivities, and they have im

294 reas at higher intensity, there is damage to biomolecules with potentially deleterious outcome in pat

295 atment of different types of illness, due to biomolecules with recognised benefits.

296 How biomolecules with shared functions find their way to spe

297 , capable of detecting low concentrations of biomolecules with significantly improved sensitivity and

298 ells requires spatial control over arrays of biomolecules within the cytomimetic environment.

299 Sciences for the absolute quantification of biomolecules without specific standards, assuming the sa

300 ue that probes the structure and dynamics of biomolecules without the need for site-directed modifica