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1 ibution in addition to light-dependent auxin biosynthesis.
2 d one-carbon units needed for de novo purine biosynthesis.
3 alyze the first committed step in triterpene biosynthesis.
4 es its expression to promote the anthocyanin biosynthesis.
5 nergy and metabolites as building blocks for biosynthesis.
6 es the complete set of genes to engineer MbA biosynthesis.
7 racterize UGTs putatively involved in SVglys biosynthesis.
8 ion of protein biosynthesis and tetrapyrrole biosynthesis.
9 nding of HBV rcDNA deproteination and cccDNA biosynthesis.
10 or to medications that interfere with sterol biosynthesis.
11 moiety of dehydroabietic acid in triptolide biosynthesis.
12 known which genes control cork triterpenoid biosynthesis.
13 icantly with the early stages of l-histidine biosynthesis.
14 the human body related to biodegradation and biosynthesis.
15 e cancer cells with energy and substrates of biosynthesis.
16 and extracellular substrates into polyketide biosynthesis.
17 dephosphorylation of Orm2, a repressor of SL biosynthesis.
18 l for iron-sulfur cluster formation and heme biosynthesis.
19 single enzyme is sufficient for rhizoferrin biosynthesis.
20 vely regulates genes involved in anthocyanin biosynthesis.
21 cing (PTGS) of the key enzyme of anthocyanin biosynthesis.
22 and genomic aspects of secondary metabolite biosynthesis.
23 on of penicillin substrates in cephalosporin biosynthesis.
24 cur independent of genetic disruption of NAD biosynthesis.
25 ential and/or ATP synthesis impaired proline biosynthesis.
26 ulose synthase like-C (CSLC) proteins in XyG biosynthesis.
27 icient translation initiation during protein biosynthesis.
28 A carboxylase and polyunsaturated fatty acid biosynthesis.
29 is fully assembled and competent in cofactor biosynthesis.
30 nk between disparate cyclases in thiopeptide biosynthesis.
31 r tree, some of which are involved in rubber biosynthesis.
32 essential transformations in natural product biosynthesis.
33 oted optimal GC polarization and cholesterol biosynthesis.
34 ting the fatty acid precursor of lipoic acid biosynthesis.
35 ential critical genes involved in flavonoids biosynthesis.
36 intracellular transport and thereby affects biosynthesis.
37 ously reported to be involved in acylglucose biosynthesis.
38 h encodes a rate-limiting enzyme in ethylene biosynthesis.
39 metabolic pathways to prioritize siderophore biosynthesis.
41 egulation of Pseudomonas aeruginosa alginate biosynthesis(3,4), as a regulator of the expression and
45 ese data provide novel insights into beta-PE biosynthesis and advance our understanding of the mechan
47 at are known to inhibit cellular cholesterol biosynthesis and are clinically prescribed to patients w
48 module, a regulatory axis composed of auxin biosynthesis and auxin perception factors controls root
49 e metagenomic approach to mine for phenazine biosynthesis and biodegradation genes, applying it to >8
51 ing telomere damage, defective mitochondrial biosynthesis and clearance, cell growth retardation, and
52 unique high metabolic flux through polyamine biosynthesis and connected one carbon metabolism in CaP
53 emical analysis showed altered cutin and wax biosynthesis and deposition in fdl1-1 mutant seedlings a
55 r host fitness, and pathways for key vitamin biosynthesis and export were identified across MAGs.
58 of the pathways that contribute to cell wall biosynthesis and how these pathways are regulated by ext
61 ate] species designated FeMo-cofactor, whose biosynthesis and insertion requires the action of over a
65 d maize B73 revealed upregulation of 12-OPDA biosynthesis and OPDA-responsive genes but downregulatio
66 plants, suggesting that JMJ14 regulated Pip biosynthesis and other downstream factors regulate SAR i
67 riants in several genes participating in GPI biosynthesis and processing lead to decreased cell surfa
69 icate deregulated fatty acid and cholesterol biosynthesis and reduced liver X receptor activation wit
72 ociated with glycolytic metabolism, collagen biosynthesis and remodeling, redox regulation and immuno
73 n of genes involved in all stages of protein biosynthesis and ribosome biogenesis during both stages
74 abolomics that unravel the interplay between biosynthesis and salvage of vitamins and cofactors in ap
75 ly postulated as we uncovered active de novo biosynthesis and substantial levels of accumulation of p
76 bacterial pathway for 9M5-FuFA and 9D5-FuFA biosynthesis and suggest the existence of homologs of th
78 duction and is involved in HH103 KPS and LPS biosynthesis and that an HH103 rkpM mutant cannot produc
79 lular localization of the final stage of TPP biosynthesis and the chemical nature of the substrates t
80 ticulum (ER), the main cellular hub of lipid biosynthesis and the entry site for the secretory pathwa
82 monoacylglycerol (2-MAG), and membrane lipid biosynthesis and transport during nodule development.
83 Additionally, we observed that amino acid biosynthesis and transport regulons, controlled by ArgR,
85 involved in inhibition of purine nucleotide biosynthesis and with GTPases that control ribosome asse
86 her tRNA(Glu) allocation limits tetrapyrrole biosynthesis and/or protein biosynthesis remains poorly
87 (eg, branched chain amino acids and arginine biosynthesis) and virulence genes (eg, beta-toxin, delta
88 rogenase (GalDH), a key enzyme for vitamin C biosynthesis, and altered the composition of phenolic co
89 gibberellin content, enhanced cutin and wax biosynthesis, and increased fruit firmness and shelf lif
90 t SnRK1 negatively regulates phenylpropanoid biosynthesis, and KFB(PALs) act as regulatory components
91 up-regulating the proline cycle and proline biosynthesis, and knockdowns of PYCR1 lead to decreased
93 complex interplay among cell-wall expansion, biosynthesis, and, in specific tissues, secondary cell w
94 the molecular basis underlying floral scent biosynthesis; and winter flowering, and highlight the ut
95 ownstream target genes function in cell wall biosynthesis, apoptosis, and maintenance of xylem cell w
96 how that active FA, 2-MAG and membrane lipid biosynthesis are essential for nodulation and rhizobia-s
97 , synthetic gene circuits for organofluorine biosynthesis are implemented in the platform bacterium P
99 agenomic pathway analysis identified steroid biosynthesis as the most underrepresented metabolic path
103 inal oxidation step of the hemolytic saponin biosynthesis branch in M. truncatula In addition, two ur
104 hibited severe defects not only in fumonisin biosynthesis but also vegetative growth and conidiation.
105 ibutors to this process, promoting cytokinin biosynthesis but repressing gibberellin production to co
106 B-SIMS) to directly visualize de novo purine biosynthesis by a multienzyme complex, the purinosome.
107 icated that TmMYB3 is involved in paclitaxel biosynthesis by activating the expression of TBT and TS.
108 s leads to inhibition of bacterial cell wall biosynthesis by disassembly of key divisome proteins, th
109 strated that the inhibition of de novo lipid biosynthesis by interfering with nematode ACC is a new n
110 SBG9 functions as a key regulator of cuticle biosynthesis by preferentially regulating expression of
113 ion, hypocotyl gravitropism, and chlorophyll biosynthesis, by physically interacting with PHYTOCHROME
116 but sugars, fatty acids and nucleotides for biosynthesis, conferring resistance to therapies targeti
117 andidate genes for straight-chain fatty acid biosynthesis confirmed their role in acylsugar metabolis
118 nzyme NadE catalyzes the last step of NAD(+) biosynthesis, converting nicotinic acid adenine dinucleo
119 xin transport, strigolactone and gibberellin biosynthesis, degradation of phospholipids and biosynthe
122 r fungal cell wall integrity, the hexosamine biosynthesis enzymes represent potential targets of anti
123 ved in bioluminescence, nonribosomal peptide biosynthesis, fatty acid activation, and beta-lactone fo
124 s in a branchpoint enzyme blocking quercetin biosynthesis, formed reduced numbers of lateral roots an
125 -defence pathway (opr7, aos1, 2, 3), terpene biosynthesis (fps3, tps2, 3, 4, 5, 7, 9, 10), benzoxazin
127 and indicate that the penultimate step of GA biosynthesis, GA 20-oxidation, is required in both the m
128 oding variations of the brassinosteroid (BR) biosynthesis gene DWARF1 (DWF1) lead to variation of the
130 sors also show altered expression of hormone biosynthesis genes and aberrant growth patterns, includi
131 sion of GmNAC42-1, GmMYB29A1, and glyceollin biosynthesis genes and metabolites, respectively, in res
132 anscriptional coexpression network of lignin biosynthesis genes during secondary cell wall formation
133 ls was associated with priming of Pip and SA biosynthesis genes to induction by low levels of SA.
134 nthesis: a ribosomal RNA helicase gene, tRNA biosynthesis genes, and a gene controlling amino acid av
136 ial, including complex I and enzymes in Fe-S biosynthesis, grow relatively well at low oxygen and thu
138 of Fe bioavailability, and increased NA/DMA biosynthesis has proved an effective Fe biofortification
140 mitochondrial protein involved in fatty acid biosynthesis, has now been identified as responsible for
142 r of cholesterol storage, uptake, efflux and biosynthesis, how these metabolic activities reprogram t
143 es enzymes for phosphatidylethanolamine (PE) biosynthesis; however, exogenous NBD-phosphatidylcholine
144 nto self-assembled networks during cellulose biosynthesis in a bacterial model, without altering the
145 apply PRISM 4 to chart secondary metabolite biosynthesis in a collection of over 10,000 bacterial ge
147 nd 943 genes involved in the phenylpropanoid biosynthesis in leaf and root tissues respectively.
148 -dependent pathway is necessary for thiamine biosynthesis in Legionella pneumophila and provide bioch
151 H7PS), at the gateway to aromatic amino acid biosynthesis in Mycobacterium tuberculosis, which shows
154 tase enzyme FabI is essential for fatty acid biosynthesis in Staphylococcus aureus and represents a p
155 ghts the importance of NAMPT-mediated NAD(+) biosynthesis in the production of cisplatin-induced sene
158 tion of phenolic compounds, through phenolic biosynthesis, in acerola during postharvest storage.
159 iferation, immune responses, and cholesterol biosynthesis, increased infiltration of neutrophils, inf
161 ficiency and resistance to a toxic polyamine biosynthesis inhibitor methylglyoxal bis-(guanylhydrazon
162 Treatment with lovastatin, a mevalonate biosynthesis inhibitor, selectively inhibited protein pr
163 ctively dividing amastigotes from ergosterol biosynthesis inhibitors (azoles), independent of parasit
165 e, and explains the failure of potent biotin biosynthesis inhibitors in standard mouse infection mode
168 erculosis and Francisella tularensis, biotin biosynthesis is a key fitness determinant during infecti
169 ed in infected cells because host hexosamine biosynthesis is being exploited by the bacteria, in part
170 The first committed step in menaquinone biosynthesis is catalyzed by MenD, a thiamine diphosphat
171 n methods to explore Sec-facilitated protein biosynthesis is hindered by the large system sizes and l
181 a key component of mitochondrial fatty acid biosynthesis, is important in generating the fatty acid
182 candidate genes for a reaction in histidine biosynthesis lacking an annotated gene and highlight met
183 ailable datasets and tools, including glycan biosynthesis models, omics datasets, and systems-level a
184 ed cell proliferation, inflammation, steroid biosynthesis, neutrophils and macrophages infiltration,
186 of Streptomyces bacteria (and genes for the biosynthesis of 2-MIB in about 50%)(7,8), suggests that
188 on of genes encoding enzymes involved in the biosynthesis of antimicrobial peptides, camalexin, and 4
190 ome analysis after biochemical inhibition of biosynthesis of branched-chain amino acids (precursors t
192 f the prodrug pyrazinamide (PZA), interrupts biosynthesis of coenzyme A in Mycobacterium tuberculosis
195 EC 2.1.1.28) catalyzes the final step in the biosynthesis of epinephrine and is a potential drug targ
196 aling module (KAI2-MAX2-SMAX1) regulates the biosynthesis of ethylene to fine-tune root and root hair
197 de experimental support for Jiang's proposed biosynthesis of exotine A and exotine B but also foresha
198 lular acetate and contributes to the de novo biosynthesis of fatty acids and Leu; peroxisome-localize
200 olved in cystine/glutamate transport and the biosynthesis of glutathione, an antioxidant that may pro
201 osynthesis, degradation of phospholipids and biosynthesis of glycerolipid, downregulation of ammonium
204 refore may be excellent tools for commercial biosynthesis of important intermediates, final drug mole
206 me-related organelles (LROs) is required for biosynthesis of most modular ascarosides as well as prev
207 arded as the main enzyme responsible for the biosynthesis of N-acylethanolamines (NAEs), a family of
208 so find that over-expressing BNA2, the first Biosynthesis of NAD(+) (kynurenine) pathway gene, reduce
209 m quinolinic acid, the precursor for de novo biosynthesis of nicotinamide adenine dinucleotide (NAD(+
210 These enzymes are frequently involved in the biosynthesis of nonproteinogenic amino acids as building
211 a large family of enzymes that catalyse the biosynthesis of oligosaccharides, polysaccharides, and g
214 f the shikimate pathway, is required for the biosynthesis of phenylalanine and tyrosine in bacteria,
215 the insertion of PlsX and thus regulates the biosynthesis of phospholipids in Gram-positive bacteria.
216 Here, we show that CAMTA123 also repress the biosynthesis of pipecolic acid (Pip) in healthy plants.
217 iched accumulation of proteins important for biosynthesis of plant defense secondary metabolites and
218 rbon into the TCA cycle, TGFbeta induced the biosynthesis of proline from glutamine in a Smad4-depend
219 S) machinery, expanding the paradigm for the biosynthesis of quinolone-gamma-lactam natural products
221 ing a plausible explanation for the enhanced biosynthesis of secondary metabolism in the glandular tr
222 e their potential therapeutic relevance, the biosynthesis of serrulatane diterpenoids has not been pr
223 se compounds serve as key precursors for the biosynthesis of several important classes of plant natur
225 itoyltransferase (SPT) catalyses the de novo biosynthesis of sphingolipids but also produces noncanon
226 PHYB2-silenced plants, we demonstrated that biosynthesis of the major tomato fruit carotenoid, lycop
227 ynthetic biology experiments to decipher the biosynthesis of the monomethylated FuFA, methyl 9-(3-met
229 this study provides useful insight into the biosynthesis of the presilphiperfolanol natural products
230 origins and variation of genes governing the biosynthesis of these crucial phenotypic traits that hav
231 transfer protein (MTP), is required for the biosynthesis of these lipoproteins, and its regulation d
232 s mode of action, resistance mechanisms, and biosynthesis of this clinically important antimicrobial
233 nce factor (pvf) operon is essential for the biosynthesis of two very different natural product scaff
234 f these enzymes are required for cholesterol biosynthesis, only inhibition of the most upstream enzym
235 americana Our data showed that a block of JH biosynthesis or JH action arrested vitellogenesis, in pa
236 f the parasite, addressing the dependency on biosynthesis or salvage of fatty acids (FAs), purine nuc
238 ntiality makes this less explored mycobactin biosynthesis pathway a promising endogenous target for n
239 d in the emergence of a novel 2-ketobutyrate biosynthesis pathway based upon the promiscuous cleavage
240 nzymes responsible for most steps of the ABA biosynthesis pathway have been identified, enzymatic rea
241 RABIDOPSIS (TAA1), a key enzyme in the auxin biosynthesis pathway in Arabidopsis thaliana is phosphor
242 entify and evaluate regulators of the lignin biosynthesis pathway in Populus deltoides by combining g
243 suggesting that intermediates in the starch biosynthesis pathway increased flux through spillover pa
247 est that the upregulation of the cholesterol biosynthesis pathway may negatively impact fish growth d
248 onding primary breast tumors, use the serine biosynthesis pathway to support mTORC1 growth signaling.
256 Here, we summarize and compare bacterial biosynthesis pathways relying on the recognition and tra
257 f genes in the terpenoid backbone and sterol biosynthesis pathways upstream of pregnenolone synthesis
258 r factor kappa B (NF-kappaB) and cholesterol biosynthesis pathways were activated, and specific cytok
259 , we discuss the diversity in structure, the biosynthesis pathways, and the functions of bacteria-spe
260 t UM cells utilize glycolytic and nucleotide biosynthesis pathways, whereas OXPHOS(low) BAP1 mutant U
262 nctionalities while providing information on biosynthesis, physiological context, and glycan fine str
263 ical, and chemical evidence that benzoxazole biosynthesis proceeds through an ester generated by an A
264 rough quantitative exploration of fatty acid biosynthesis processes for optimal biofuels, renewable f
266 ial roles in development, signaling, hormone biosynthesis, regulation of gene expression, stress resi
268 nd the stem tissue-specificity of paclitaxel biosynthesis-related enzymes remain largely unknown.
271 of a man-made explosive and in benzastatins biosynthesis, respectively, as very efficient C-H aminas
273 mnat activities are essential for all NAD(+) biosynthesis routes, and understanding the regulation of
274 tes of the shikimate and aromatic amino acid biosynthesis (SA) pathways (upstream of BNA2), which pro
276 Pv03 dirigent-like gene, involved in lignin biosynthesis, showed a base-pair substitution that is as
277 regulatory programs, including phytohormone biosynthesis, signaling, and response, which were well c
278 and enzymes for the first four steps of MbA biosynthesis, starting from the flavonol precursor myric
281 rucial roles of adenylate-forming enzymes in biosynthesis, this also severely limits our ability to p
284 recycles one-carbon units lost to polyamine biosynthesis to the methionine cycle to overcome stress.
286 ifferences in nucleotide salvage and de novo biosynthesis using a histologically heterogeneous breast
287 oll-like receptors via NF-kappaB, eicosanoid biosynthesis via the lipoxygenase pathway and IL-2 biosy
288 th clv2/crn signaling and heat-induced auxin biosynthesis via YUCCA family genes are synergistically
290 that phosphocholine and phosphatidylcholine biosynthesis was markedly elevated in Traf3 (-/-) mouse
291 which tyrosine hydroxylase (TH), and thus DA biosynthesis, was conditionally ablated using either flo
292 (rbcL and RbcS), and enzymes of chlorophyll biosynthesis were down-regulated in the yellow leaf tiss
294 e insensitive to a chemical inhibitor of Trp biosynthesis, which is a phenotype previously observed i
295 cent knowledge gained in the genetics of CHC biosynthesis, which is just beginning to incorporate wor
296 e confirmed that roots are autonomous for GA biosynthesis, which occurs in multiple tissues, with the
297 ochondrial redox generation promoted proline biosynthesis, while reducing mitochondrial redox potenti
298 P-glycosyltransferase, the first step in GPI biosynthesis, with good selectivity over the human funct
299 s are consistent with the early stages of GA biosynthesis within the root occurring in the meristemat
300 e Delta-14 reductase activity in cholesterol biosynthesis, yet little is known about their post-trans