ライフサイエンスコーパス: biosynthetic

1 Biosynthetic access to leubethanol will enable pathway d

2 ntaining mitochondrial electron transfer and biosynthetic activity in cancer cells exposed to metabol

3 omic analysis demonstrated that reduced tRNA biosynthetic activity produces a selective homeostatic r

4 Interference with their biosynthetic activity results in an irreversible growth

5 rstand the roles of different classes of TAG biosynthetic acyltransferases in seed oil biosynthesis,

6 Biosynthetic AgNPs also represent a promising alternativ

7 r compete with their "neighbors" to maintain biosynthetic and bioenergetic demands while escaping imm

8 GA homeostasis is achieved via complex biosynthetic and catabolic pathways, whose exact activit

9 ramework that describes the contributions of biosynthetic and degradative mechanisms to r-protein abu

10 ptome analysis indicated activation of lipid biosynthetic and oxidative-stress response pathways, inc

11 st, in certain cell types, knockout of lipid biosynthetic and peroxisomal genes causes fitness defect

12 the macroscopic level, brassinosteroid (BR) biosynthetic and receptor mutants have similar growth de

13 Ts are especially characterized by catabolic/biosynthetic and transport processes including cell wall

14 this review, we will discuss the reactivity, biosynthetic, and mechanistic proposals for the alternat

15 hese genes appear to alleviate energetic and biosynthetic bottlenecks to viral production.

16 he need for donor corneas include pre-formed biosynthetic buttons and in situ-forming matrices that s

17 ry bile acids (PBAs) in a process reliant on biosynthetic capabilities possessed by few microbes.

18 cells undergo an irreversible loss of their biosynthetic capacities as a consequence of differentiat

19 esponse (UPR), which are designed to restore biosynthetic capacity of the ER.

20 erol/oxysterol and phosphatidylethanolamine) biosynthetic cascades as being centrally involved in MND

21 ontribute both to PG elongation and division biosynthetic complexes based on its localization and gen

22 mental evidence consistent with the proposed biosynthetic connection between caryophyllene and the pr

23 C-MRR measurements may initiate a new era in biosynthetic/degradation and geochemical isotopic compou

24 positive carrier vesicles, which mediate the biosynthetic delivery of Mega to the SJ.

25 amines leading to their secretion and drives biosynthetic demand.

26 y utilize glutamine to meet bioenergetic and biosynthetic demands of rapid cell growth.

27 Cancer cells within the biosynthetic domains are characterized by elevated level

28 structure and the chemical structure of the biosynthetic end-product, has become a cornerstone of kn

29 The siderophore biosynthetic enzyme A (SidA) ornithine hydroxylase from

30 The pyrimidine biosynthetic enzyme dihydroorotate dehydrogenase (DHODH)

31 n increased number of neurons expressing the biosynthetic enzyme for serotonin, tryptophan-hydroxylas

32 osyltransferase (NAMPT), an essential NAD(+) biosynthetic enzyme in skeletal muscle, decreased by 14%

33 is colocalized with tyrosine hydroxylase, a biosynthetic enzyme in the dopamine pathway.

34 ter represses NLRC4 and the lysophospholipid biosynthetic enzyme iPLA2, causing a decline in intracel

35 racterization of an intact animal polyketide biosynthetic enzyme opens the door to understanding the

36 phate hydrolase LpxH is an essential lipid A biosynthetic enzyme that is conserved in the majority of

37 SUPPRESSION1 (LLS1) gene, encoding the auxin biosynthetic enzyme YUCCA1 in Medicago truncatula.

38 l acyltransferase (AtPDAT1) is the major TAG biosynthetic enzyme), and enhanced TAG biosynthesis by e

39 These include IMPDH2, encoding a key purine biosynthetic enzyme, for which robust evidence existed f

40 rt that spermine synthase (SMS), a polyamine biosynthetic enzyme, is overexpressed in CRC.

41 ls and activity of a rate-limiting polyamine biosynthetic enzyme, ornithine decarboxylase (ODC).

42 major genomic regions, some of which harbor biosynthetic enzyme-coding genes; can be accurately pred

43 The genes encoding the identified biosynthetic enzymes are present in clusters of duplicat

44 nic plants through down-regulation of lignin biosynthetic enzymes can induce expression of defense re

45 nsport system for NADP(+) and luminal NAD(+) biosynthetic enzymes integrate signals from a chemokine

46 tic challenge, we sought to characterize the biosynthetic enzymes that assemble these NPs for applica

47 position involve the overexpression of lipid biosynthetic enzymes, but how these enzymes are assemble

48 ns controlling the expression of cholesterol biosynthetic enzymes, resulting in optimal recruitment o

49 in phosphate and metal uptake, and cofactor biosynthetic enzymes.

50 d utilizes multiple different classes of TAG biosynthetic enzymes.

51 f non-natural GPA peptides by these powerful biosynthetic enzymes.

52 ic analysis of the genes of the echinocandin biosynthetic family indicated that most of the predicted

53 The trans-AT family of modular PKSs, whose biosynthetic frameworks diverge significantly from those

54 Mutation of key genes in the FSA biosynthetic gene (FUB) cluster in Fusarium oxysporum f.

55 6 was sequenced to identify the levesquamide biosynthetic gene cluster (BGC).

56 t the identification of the quinolactacin A2 biosynthetic gene cluster and elucidate the enzymatic ba

57 The biosynthetic gene cluster for FA has been identified, bu

58 Here, we identified the Brevianamide A biosynthetic gene cluster from Penicillium brevicompactu

59 ed following genome-mined discovery of a new biosynthetic gene cluster in extremotolerant Streptomyce

60 bolomics and RNA sequencing, we discovered a biosynthetic gene cluster in tomato (Solanum lycopersicu

61 Although the biosynthetic gene cluster responsible for CTA production

62 The MIBiG (Minimum Information about a Biosynthetic Gene Cluster) Data Standard and Repository

63 functions of several proteins encoded by the biosynthetic gene cluster, which was found in the genome

64 cation and inactivation of the corresponding biosynthetic gene cluster.

65 chrome P450 enzyme BotCYP from a bottromycin biosynthetic gene cluster.

66 Mammalian microbiomes encode thousands of biosynthetic gene clusters (BGCs) and represent a new fr

67 Biosynthetic gene clusters (BGCs) are operonic sets of m

68 Biosynthetic gene clusters (BGCs) encode small molecules

69 ide the effective prioritization of specific biosynthetic gene clusters (BGCs) for drug development a

70 onships of the numerous candidate triterpene biosynthetic gene clusters (BGCs) observed.

71 Antibiotic biosynthetic gene clusters (BGCs) produce bioactive meta

72 s genomics has uncovered the large number of biosynthetic gene clusters (BGCs) that encode for novel

73 ted T1PKS monomodules from monomodular T1PKS biosynthetic gene clusters (BGCs) were experimentally co

74 Numerous examples of biosynthetic gene clusters (BGCs), including for compoun

75 layed a central role through the analysis of Biosynthetic Gene Clusters (BGCs).

76 Microbial biosynthetic gene clusters are a valuable source of bioa

77 rabidopsis thaliana Our analyses reveal that biosynthetic gene clusters are embedded in local hot spo

78 beta-lactone synthetases in uncharacterized biosynthetic gene clusters conserved in >90 different st

79 lved in the synthesis of secondary metabolic biosynthetic gene clusters reflect a wealth of previousl

80 singly refined syn-BNP-based explorations of biosynthetic gene clusters should allow for more rapid i

81 Biosynthetic gene clusters that encode pathways for spec

82 Microbial genomes harbor an abundance of biosynthetic gene clusters, but most are expressed at lo

83 tinomycetes reveals an untapped reservoir of biosynthetic gene clusters, but prioritization is requir

84 An increasing number of natural product biosynthetic gene clusters, to which no known molecules

85 y to predict natural product structures from biosynthetic gene clusters.

86 and then produce small molecules inspired by biosynthetic gene clusters.

87 survey of P450 enzymes associated with RiPP biosynthetic gene clusters.

88 mutant d(^im) , which has a lesion in the BR biosynthetic gene DWARF (DWF), and in the bzr1 mutant, w

89 nd corresponding proinflammatory and steroid biosynthetic gene networks, may represent biomarkers and

90 ana) mutants for the essential glucosinolate biosynthetic gene ROOTY (RTY) that exhibit a range of ph

91 leaves and upregulated the expression of its biosynthetic genes (CsTDC, CsT5H, CsSNAT, CsASMT, and Cs

92 of volatiles and transcripts of key volatile biosynthetic genes also were greatly reduced in the abse

93 physiology, an incomplete knowledge of their biosynthetic genes and a lack of genetic tools to enable

94 have been isolated from N. nucifera, its BIA biosynthetic genes and enzymes remain unknown.

95 the transcriptional regulation of carotenoid biosynthetic genes concerning carotenoid accumulation du

96 ) as well as the strigolactone apocarotenoid biosynthetic genes DWARF27 (D27), CAROTENOID CLEAVAGE DI

97 ngiosperms, and we identified their putative biosynthetic genes in N. colorata.

98 study confirms the presence of the necessary biosynthetic genes in orange carrots for production of a

99 Likewise, expression of upstream monolignol biosynthetic genes was increased in both bmr12 and bmr12

100 vealed correlated expression of the relevant biosynthetic genes with carotenoid accumulation, but als

101 NINJA jointly regulate the expression of GSL biosynthetic genes, and thus constitute a molecular mech

102 rric-siderophore receptor is adjacent to the biosynthetic genes, suggesting that these metabolites ma

103 tandem arrays of isoprenoid and cannabinoid biosynthetic genes.

104 sic acid) and the transcript levels of their biosynthetic genes.

105 mutations in Complex I subunits genes or CoQ biosynthetic genes.

106 dependent of genomic context and neighboring biosynthetic genes.

107 more predictive of metabolite features than biosynthetic genes.

108 ranscriptional regulation of phenylpropanoid biosynthetic genes.

109 ase PBP1b and is sufficient to stimulate its biosynthetic glycosyltransferase (GTase) activity.

110 tion and characterization of plant cell wall biosynthetic glycosyltransferases (GTs).

111 arboxylate reductase 1 (PYCR1) catalyzes the biosynthetic half-reaction of the proline cycle by reduc

112 s of a metabolic pathway, are proposed to be biosynthetic "hotspots" within the cell.

113 ow mitochondria balance their dual role as a biosynthetic hub as well as a center for cellular respir

114 articularly to the azole class of ergosterol biosynthetic inhibitors, is a growing global health prob

115 The synthesis of an elusive biosynthetic intermediate also allowed a concise synthes

116 dic acid (PA) is both a central phospholipid biosynthetic intermediate and a multifunctional lipid se

117 immune recognition of the lipopolysaccharide biosynthetic intermediate beta-ADP-heptose by the ALPK1/

118 We also report a biosynthetic intermediate probe (BIP)-based target ident

119 and in vitro enzyme studies to identify key biosynthetic intermediates and expose intricate redox ta

120 ream metabolite, alphaKG, without increasing biosynthetic intermediates necessary for cell proliferat

121 presumably sample distinct conformations, as biosynthetic intermediates tethered to their acyl carrie

122 reus, like all organisms, requires essential biosynthetic intermediates to synthesize macromolecules.

123 nes, radical chemistry, and novel and unique biosynthetic intermediates.

124 th exogenous (environmental) and endogenous (biosynthetic) L-arginine influence biofilm formation by

125 genomes have revealed an enormous number of biosynthetic loci encoding RiPPs but whose products rema

126 ive E. faecium capsular polysaccharide (cps) biosynthetic locus, with different mutations arising ind

127 From biosynthetic logic, we hypothesized that this single enz

128 edox tailoring reactions that appear to defy biosynthetic logic.

129 tal strategies that oversimplify the complex biosynthetic machineries of living cells.

130 proach that is holistically patterned off of biosynthetic machinery for terpene synthesis can be used

131 This study establishes how the albomycin biosynthetic machinery generates its antimicrobial compo

132 Despite disparate biosynthetic machinery, alkaloid, terpene, and polyketid

133 rboxylation step, indicating a hypervariable biosynthetic machinery.

134 t, which would not be accessible through the biosynthetic machinery.

135 ygenase pathway is confirmed as an important biosynthetic mechanism for the generation of free and gl

136 metabolic machinery that provides energy and biosynthetic molecules for cell building.

137 lycan regulators and adaptors are part of PG biosynthetic multi-enzyme complexes, regulating and pote

138 ds involved, we tested an array of flavonoid biosynthetic mutants, eliminating roles for anthocyanins

139 s and NMR analysis were performed to confirm biosynthetic N(2) reduction to NH(3) .

140 ge chromosomal deletions within the anthrose biosynthetic operon of B. anthracis strains from Chile a

141 ntified putative bacterial exopolysaccharide biosynthetic operons and in other fungal genomes.

142 ics to rediscover evolidine and decipher its biosynthetic origin from a short precursor just 48 resid

143 xperiments provide further insights into the biosynthetic origin of isothiazolinones.

144 its accumulation to ~0.7% in castor oil, the biosynthetic origin of which had remained enigmatic for

145 structurally intriguing metabolite of mixed biosynthetic origin, is reported.

146 eroterpenoids are natural products of hybrid biosynthetic origins-derived from both terpenoid and pol

147 iguing biological activities, and mysterious biosynthetic origins.

148 sed the newly identified genes to engineer a biosynthetic pathway (comprising 16 enzymes in total) to

149 stead, glucose metabolized by the hexosamine biosynthetic pathway (HBP) allows nuclear localization o

150 , we identify the requirements of hexosamine biosynthetic pathway (HBP) and O-GlcNAc transferase (OGT

151 lar, an enhanced flux through the Hexosamine Biosynthetic Pathway (HBP) has been tightly linked to PC

152 The hexosamine biosynthetic pathway (HBP) plays critical roles in nutri

153 et the foundation to fully reveal triptolide biosynthetic pathway and consequently the heterologous b

154 HIV Nef to target distinct stages of the MR biosynthetic pathway and dramatically reduce MR expressi

155 The BH4 biosynthetic pathway and GCH1 have been identified as pr

156 his study concludes the discovery of the MbA biosynthetic pathway and provides the complete set of ge

157 We introduce a non-natural substrate biosynthetic pathway and use engineered glycosyltransfer

158 htly correlated with upregulation of the Trp biosynthetic pathway but not with changes in central car

159 We present recent examples of de novo biosynthetic pathway discovery that employ various innov

160 evels in the CA for the 13 enzymes of the JH biosynthetic pathway during the molting cycle of 4(th) i

161 SREBP1 SDM and the induction of cholesterol biosynthetic pathway enzymes that produce retinoid-relat

162 ts revealed that genes encoding the complete biosynthetic pathway for brassinosteroid phytohormones a

163 We characterize the biosynthetic pathway for the sialic acid-like sugar pseu

164 We show that copy numbers of triptolide biosynthetic pathway genes are impacted by a recent whol

165 e results suggest that manipulation of auxin biosynthetic pathway genes can be an effective approach

166 tes to transcriptional activity of clustered biosynthetic pathway genes in Arabidopsis thaliana Our a

167 ate, and partially validate, the hydrocarbon biosynthetic pathway in An. gambiae.

168 ulated and accelerated activation of the SCW biosynthetic pathway in fiber cells, as revealed by tran

169 It is known that a truncated steroid biosynthetic pathway in lampreys produces two predominan

170 Reconstitution of the coformycin biosynthetic pathway in vitro demonstrates that it overl

171 Nocardia brasiliensis and reconstituted the biosynthetic pathway in vitro to link the gene cluster t

172 hree enzymes in the postsqualene cholesterol biosynthetic pathway including EBP, DHCR7, and DHCR24.

173 endocannabinoid, and although its canonical biosynthetic pathway involving phosphoinositide-specific

174 The lignin biosynthetic pathway is highly conserved in angiosperms,

175 entification of genes and elucidation of the biosynthetic pathway leading to triptolide are the prere

176 Nutrient flux into the hexosamine biosynthetic pathway leads to protein posttranslational

177 sults highlight that the O(2)-independent UQ biosynthetic pathway may represent a target for antibiot

178 A plausible biosynthetic pathway of 1 was proposed.

179 ere, we report that the last reaction in the biosynthetic pathway of APDs, catalyzed by F(420)H(2)-de

180 fully recode, construct and characterize the biosynthetic pathway of bikaverin, a tetracyclic polyket

181 s of (2S,6S)-6-methyl pipecolate 1, from the biosynthetic pathway of citrinadin.

182 We elucidated the biosynthetic pathway of compounds in the citridone famil

183 ial avenues of study, including learning the biosynthetic pathway of cypridinid luciferin and genomic

184 dvanced analytical techniques to dissect the biosynthetic pathway of mono- and dimethyl FuFAs and the

185 mologous to the last step in the acylsucrose biosynthetic pathway of tomato (Solanum lycopersicum).

186 d the numerous studies conducted, the SVglys biosynthetic pathway remains largely unknown.

187 cluster for FA has been identified, but the biosynthetic pathway remains unclarified.

188 identified several genes in the sphingolipid biosynthetic pathway that are required for Gb3 synthesis

189 The detailed biosynthetic pathway to 1 was established by heterologou

190 rferons (IFNs) can reprogram the cholesterol biosynthetic pathway to facilitate innate immune respons

191 f genes encoding enzymes of the isoflavonoid biosynthetic pathway was also maximal in these cultivars

192 noparticles (FNP) on emerging (non-aflatoxin biosynthetic pathway) toxins production in mycelia and y

193 ate (ZMP), an intermediary of de novo purine biosynthetic pathway, and depletion of ATP.

194 wledge of the Thi5 enzyme, the corresponding biosynthetic pathway, and the role of metabolic network

195 ut not downstream enzymes in the cholesterol biosynthetic pathway, as a target in APC mutant colorect

196 Eicosanoids were grouped by biosynthetic pathway, defined by (1) the fatty acid prec

197 and a homologous enzyme from the kainic acid biosynthetic pathway, KabA, to reengineer their isoprene

198 ion events are key regulators of the protein biosynthetic pathway, leading from rDNA transcription an

199 ikely through its regulation of the cysteine biosynthetic pathway, plays a key role in the virulence

200 erization of TnmH from the tiancimycin (TNM) biosynthetic pathway, revealing that (i) TnmH catalyzes

201 final two reactions in the mithramycin (MTM) biosynthetic pathway, the Baeyer-Villiger opening of the

202 lls revealed that genes from the L-histidine biosynthetic pathway, the purine, pyrimidine de novo syn

203 compensate for the deletion of an essential biosynthetic pathway.

204 ng us to propose an updated model of the TPP biosynthetic pathway.

205 etween eicosanoids and case status varied by biosynthetic pathway.

206 tes the description of the entire lincomycin biosynthetic pathway.

207 synthesized but fails to progress in the CI biosynthetic pathway.

208 vely inhibits a key enzyme in the isoleucine biosynthetic pathway.

209 PQQ biosynthesis within an oxygen-dependent biosynthetic pathway.

210 -phosphate synthase enzyme of the riboflavin biosynthetic pathway.

211 yzing the committed step in the tetrapyrrole biosynthetic pathway.

212 l carbocation intermediates on the taxadiene biosynthetic pathway.

213 mato fruits and genetically engineered their biosynthetic pathway.

214 ion of several key genes in the sphingolipid biosynthetic pathway.

215 e first and rate-limiting enzyme in the heme biosynthetic pathway.

216 view, we discuss how nitrogen is utilized in biosynthetic pathways and highlight different metabolic

217 How activated B cells build biosynthetic pathways and organelle structures necessary

218 e the critical importance of the meibum, its biosynthetic pathways and the roles of individual lipid

219 mechanisms underpinning the evolution of new biosynthetic pathways are not well-understood.

220 have a role in the, as yet uncharacterised, biosynthetic pathways around salicortin, the major salic

221 mophila, Francisella species lack putrescine biosynthetic pathways because of genomic decay.

222 land plants, suggesting that brassinosteroid biosynthetic pathways differ between earlier- and later-

223 Existing biosynthetic pathways for natural products, such as vita

224 Characterizing the structural components and biosynthetic pathways for these polysaccharides is key t

225 Although their biosynthetic pathways have been extensively studied, the

226 y plastic, and that dynamic GNs generate new biosynthetic pathways in different Brassicaceae lineages

227 several phytohormone and structural polymer biosynthetic pathways in land plants.

228 e carbocation intermediates that connect the biosynthetic pathways leading to the sand fly pheromone

229 omic groups is important for determining the biosynthetic pathways of bioluminescent substrates, whic

230 are not informative for determination of the biosynthetic pathways of the luciferins.

231 DDAP is a tool for predicting the biosynthetic pathways of the products of type I modular

232 lysosomal degradation are either recycled in biosynthetic pathways or are further metabolized to prod

233 induced by perturbation of endogenous lipid biosynthetic pathways or exogenous application of lipid.

234 osanoids derived from AA via the CYP and LOX biosynthetic pathways were positively associated with SG

235 requirements and provide building blocks for biosynthetic pathways, metabolism is now appreciated for

236 y metabolites are synthesized through unique biosynthetic pathways, plants must orchestrate their pro

237 It is frequently invoked in biosynthetic pathways, so it is especially suitable for

238 e synthesized through apparently independent biosynthetic pathways.

239 he discovery of functional-related genes and biosynthetic pathways.

240 integrates ceramide, PEMT, and glycerolipid biosynthetic pathways.

241 condary metabolites produced by noncanonical biosynthetic pathways.

242 pedite engineering of strains for optimising biosynthetic pathways.

243 lved in the sulfur assimilation and cysteine biosynthetic pathways.

244 boside (NR), while down-regulating other NAD biosynthetic pathways.

245 omoting glyceollin turnover and/or competing biosynthetic pathways.

246 d mutations in biotin, pyridoxine and niacin biosynthetic pathways.

247 ble docking domains information in bacterial biosynthetic pathways.

248 sity-generating step in fungal meroterpenoid biosynthetic pathways: the multibond-forming polyene cyc

249 strongly dependent upon activation of lipid biosynthetic pathways; activation of these pathways exhi

250 vides detailed mechanistic insight into this biosynthetic peculiarity and establishes a molecular fra

251 SCRaMbLE can yield strains with improved biosynthetic phenotypes but is limited by screening capa

252 * mutants exhibited variable deficiencies in biosynthetic post-translational maturation, membrane sor

253 This study explores antimicrobial biosynthetic potential and diversity of actinobacteria f

254 hibiting pateamines, we identified extensive biosynthetic potential distributed among a broad phyloge

255 est, allowing us to get a better view of the biosynthetic potential of the biosphere.

256 These results show biosynthetic precursor production to be temporally regul

257 In graminaceous plants NA serves as the biosynthetic precursor to 2' -deoxymugineic acid (DMA),

258 viously on the basis of differences in their biosynthetic precursors and chemical degradation product

259 calculations on rearrangements of potential biosynthetic precursors to the sesquiterpenoid illisimon

260 lead to differential requirements in energy, biosynthetic precursors, and signaling intermediates.

261 A global understanding of which biosynthetic processes are involved and how they are tem

262 tical mechanism by which E. coli coordinates biosynthetic processes during starvation.

263 e mass is mainly reallocated from amino acid biosynthetic processes into translation, which enables a

264 ated from amino acids (AAs) and utilized for biosynthetic processes through transamination and deamin

265 Sulfur compound, methionine and cysteine biosynthetic processes were identified as significantly

266 e of intracellular geometry, organelles, and biosynthetic processes.

267 duced expression of genes that regulate core biosynthetic processes.

268 anosine triphosphatases (GTPases) and drives biosynthetic processes.

269 ocessed pseudogenes, with likely overlapping biosynthetic processes.

270 dentify enzymatic pathways that enable their biosynthetic production.

271 allows simultaneous mapping of thousands of biosynthetic products such as lipids but has needed a me

272 t is pivotal for subsequent bioenergetic and biosynthetic programs and licences T cell receptor drive

273 iates, generally thought to be important for biosynthetic purposes, as signaling molecules with funct

274 ethylhopanoid abundance, indicating that the biosynthetic reaction mechanism is cobalamin dependent.

275 re, underlying protein, and disease-relevant biosynthetic regulation is currently elusive.

276 r metabolism to provide energy and essential biosynthetic requirements for efficient replication.

277 abolic pathways to meet the bioenergetic and biosynthetic requirements is a principal characteristic

278 mine is used for generation of energetic and biosynthetic requirements of the MDV infection, while gl

279 c programs that adjust to meet energetic and biosynthetic requirements to support effector functions,

280 Novel biosynthetic routes can now be designed by the rearrange

281 Here we review recently discovered biosynthetic routes to freestanding nonproteinogenic alp

282 able, microbes shift from conversion-focused biosynthetic routes to more encompassing DNA-driven path

283 analogue of pheomelanin through chemical and biosynthetic routes using selenocystine as a feedstock.

284 somal trafficking for egress rather than the biosynthetic secretory pathway more commonly used by oth

285 Thus, biosynthetic status is an important indicator of soybean

286 By reconstituting initial biosynthetic steps in a heterologous host and generating

287 hese enzymes catalyze the previously unknown biosynthetic steps including 6-epimerization, 6,8-dehydr

288 heir fungal producers and uncovered that the biosynthetic steps require multiple iterative enzymes.

289 In summary, MFC biosensor with biosynthetic strain is an efficient and affordable syste

290 aluable bioactivities based on combinatorial biosynthetic strategies.

291 This biosynthetic strategy enables the host myxobacterium to

292 Our biosynthetic strategy exploits the large number of natur

293 nature and function, beta-cells are prone to biosynthetic stress with limited measures for self-defen

294 o the heterogeneity of bacterial lipoprotein biosynthetic systems.

295 planta, and gene expression analysis of the biosynthetic TPSs showed distinct and, albeit moderately

296 red novel compounds originating from diverse biosynthetic transformations that reveal unexpected inte

297 In these pathways, diverse biosynthetic transformations, ranging from isomerization

298 ns trpR, an intergenic region (IGR), and the biosynthetic trpB and trpA open-reading frames.

299 at what point during Golgi maturation does a biosynthetic vacuolar cargo depart from the maturing cis

300 These data reveal a natural product biosynthetic workaround that evolved to bypass a missing