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1 d from UDP-GlcNAc produced in the hexosamine biosynthetic pathway.
2 ion of several key genes in the sphingolipid biosynthetic pathway.
3 ated its capacity by optimizing the lycopene biosynthetic pathway.
4 nal reaction in the diaminopimelate l-lysine biosynthetic pathway.
5 cerolipid formed by the plastid galactolipid biosynthetic pathway.
6 utes a critical step in this l-tartaric acid biosynthetic pathway.
7 A. annua plants can express the artemisinin biosynthetic pathway.
8 ate a nearly complete description of the PQQ biosynthetic pathway.
9 etabolites formed by derailment of the major biosynthetic pathway.
10 iting step in the de novo guanine nucleotide biosynthetic pathway.
11 andis was expressed to optimize the limonene biosynthetic pathway.
12 iolin, an intermediate in the napyradiomycin biosynthetic pathway.
13 t the MeJA application activated the related biosynthetic pathway.
14 legans are reported to lack a de novo NAD(+) biosynthetic pathway.
15 l, rate limiting and regulatory genes of CPT biosynthetic pathway.
16 ansferase (AICARFT), an enzyme in the purine biosynthetic pathway.
17 tone antibiotic obafluorin and delineate its biosynthetic pathway.
18 tion of structural genes of the capsaicinoid biosynthetic pathway.
19 de as the final steps in the malbrancheamide biosynthetic pathway.
20 he activity of a specific enzyme in the heme biosynthetic pathway.
21 renylphenol, an early intermediate of the UQ biosynthetic pathway.
22 e first and rate-limiting enzyme in the heme biosynthetic pathway.
23 compensate for the deletion of an essential biosynthetic pathway.
24 ng us to propose an updated model of the TPP biosynthetic pathway.
25 etween eicosanoids and case status varied by biosynthetic pathway.
26 tes the description of the entire lincomycin biosynthetic pathway.
27 synthesized but fails to progress in the CI biosynthetic pathway.
28 vely inhibits a key enzyme in the isoleucine biosynthetic pathway.
29 PQQ biosynthesis within an oxygen-dependent biosynthetic pathway.
30 -phosphate synthase enzyme of the riboflavin biosynthetic pathway.
31 yzing the committed step in the tetrapyrrole biosynthetic pathway.
32 l carbocation intermediates on the taxadiene biosynthetic pathway.
33 mato fruits and genetically engineered their biosynthetic pathway.
34 lved in the sulfur assimilation and cysteine biosynthetic pathways.
35 as well as molybdopterin and selenocysteine biosynthetic pathways.
36 riven by environmentally-sensitive intrinsic biosynthetic pathways.
37 offs between photoactive and non-photoactive biosynthetic pathways.
38 abundance is regulated coordinately with PC biosynthetic pathways.
39 boside (NR), while down-regulating other NAD biosynthetic pathways.
40 RE, whose genomes lack purine and pyrimidine biosynthetic pathways.
41 rmediates, and incorporated into glycans via biosynthetic pathways.
42 rate the characterization of natural product biosynthetic pathways.
43 Pictet-Spengler reaction, that mimics their biosynthetic pathways.
44 ng Ols with three other types of hydrocarbon biosynthetic pathways.
45 tion of key enzymes of lipid and cholesterol biosynthetic pathways.
46 ant role in the control of metabolic flux in biosynthetic pathways.
47 s is most likely a general tool for specific biosynthetic pathways.
48 e therapeutically enhanced by blocking lipid biosynthetic pathways.
49 gically harmful cross-talk between essential biosynthetic pathways.
50 cated red cluster and exogenous hbn cluster) biosynthetic pathways.
51 requires a complete understanding of NAD(+) biosynthetic pathways.
52 c reprogramming; and (4) inhibition of lipid biosynthetic pathways.
53 ino group in the bacillosamine or perosamine biosynthetic pathways.
54 acid, S-adenosyl methionine (SAM) and folate biosynthetic pathways.
55 omoting glyceollin turnover and/or competing biosynthetic pathways.
56 ed by so-called cross talk between different biosynthetic pathways.
57 le, tricarboxylic acid cycle, and amino acid biosynthetic pathways.
58 d mutations in biotin, pyridoxine and niacin biosynthetic pathways.
59 ble docking domains information in bacterial biosynthetic pathways.
60 e synthesized through apparently independent biosynthetic pathways.
61 he discovery of functional-related genes and biosynthetic pathways.
62 integrates ceramide, PEMT, and glycerolipid biosynthetic pathways.
63 condary metabolites produced by noncanonical biosynthetic pathways.
64 pedite engineering of strains for optimising biosynthetic pathways.
65 is method to construct a functional lycopene biosynthetic pathway (11.9 kb encoding 10 genes) in Esch
67 complete elucidation of the malbrancheamide biosynthetic pathway accomplished through complementary
68 strongly dependent upon activation of lipid biosynthetic pathways; activation of these pathways exhi
69 (or FamC1) protein encoded in the ambiguine biosynthetic pathway, an isomerocyclase that can rearran
70 acterized enzyme defects in the complex heme biosynthetic pathway and are divided into categories of
71 et the foundation to fully reveal triptolide biosynthetic pathway and consequently the heterologous b
72 HIV Nef to target distinct stages of the MR biosynthetic pathway and dramatically reduce MR expressi
73 enous fatty acids by suppressing its de novo biosynthetic pathway and exclusively utilizing extracell
75 coding enzymes of the de novo serine-glycine biosynthetic pathway and glucose transporter 1 (GLUT1).
78 oldip2 deficiency upregulates the hexosamine biosynthetic pathway and OGT (O-linked N-acetylglucosami
79 his study concludes the discovery of the MbA biosynthetic pathway and provides the complete set of ge
80 based stimulation of the iron-sulfur cluster biosynthetic pathway and suggest new strategies to overc
81 explore the biological role of the LE in the biosynthetic pathway and the etiology of cone dystrophy
83 e structure and can be produced by a de novo biosynthetic pathway and, alternatively, by the Kennedy
84 k inhibition of the corresponding amino acid biosynthetic pathway and, in this way, increases amino a
85 nd-alone catalysts, components of artificial biosynthetic pathways and biocatalytic or chemoenzymatic
86 and has led to the ability to engineer novel biosynthetic pathways and hence 'unnatural natural produ
87 view, we discuss how nitrogen is utilized in biosynthetic pathways and highlight different metabolic
88 man transporter ATP7B delivers copper to the biosynthetic pathways and maintains copper homeostasis i
89 trategies, including, among others, altering biosynthetic pathways and modifying the associations and
91 1) kinase promotes cell growth by activating biosynthetic pathways and suppressing catabolic pathways
92 e the critical importance of the meibum, its biosynthetic pathways and the roles of individual lipid
93 xplored bacterial lineages likely have novel biosynthetic pathways and unknown biochemical features.
95 e advanced our understanding of the betalain biosynthetic pathway, and discuss the impact of phylogen
96 wledge of the Thi5 enzyme, the corresponding biosynthetic pathway, and the role of metabolic network
100 skeletons have been reported from mints, but biosynthetic pathways are known for just a few of these.
102 at the cellular and metabolic levels, entire biosynthetic pathways are present in all plant groups, a
104 idine synthase, two enzymes of the polyamine biosynthetic pathway, are critical for promastigote prol
105 have a role in the, as yet uncharacterised, biosynthetic pathways around salicortin, the major salic
106 es, which revealed the mevalonate and folate biosynthetic pathways as MESN-selective dependencies.
107 ut not downstream enzymes in the cholesterol biosynthetic pathway, as a target in APC mutant colorect
108 es involved in both protein biosynthesis and biosynthetic pathways, as well as of several stress-indu
111 htly correlated with upregulation of the Trp biosynthetic pathway but not with changes in central car
112 valinomycin synthetase(12), we elucidate the biosynthetic pathway by which it progressively oligomeri
113 host fatty acid incorporation into bacterial biosynthetic pathways by the Saureus fatty acid kinase (
114 rived from the flavonoid and hydroxystilbene biosynthetic pathways can also function as true lignin m
115 recent evidence that places eoxPLs and their biosynthetic pathways center stage in immunoregulation.
116 sed the newly identified genes to engineer a biosynthetic pathway (comprising 16 enzymes in total) to
119 land plants, suggesting that brassinosteroid biosynthetic pathways differ between earlier- and later-
121 biochemical approaches, we delineated the SA biosynthetic pathway downstream of isochorismate in Arab
122 evels in the CA for the 13 enzymes of the JH biosynthetic pathway during the molting cycle of 4(th) i
123 nd invasion of hosts plus the absence of key biosynthetic pathways (e.g., lipids) in metagenome assem
125 with acceptor proteins for sulfur-containing biosynthetic pathways, elucidating mechanistic details o
127 sensitivity to inhibition of the cholesterol biosynthetic pathway enzyme squalene epoxidase (SQLE).
128 SREBP1 SDM and the induction of cholesterol biosynthetic pathway enzymes that produce retinoid-relat
129 orter substrate specificities to that of the biosynthetic pathways, exemplify how transporter substra
131 sue context in determining the choice of NAD biosynthetic pathway, explain the failure of NAMPT inhib
133 ts revealed that genes encoding the complete biosynthetic pathway for brassinosteroid phytohormones a
134 rin, but culturing them is difficult and the biosynthetic pathway for firefly luciferin remains uncle
135 e metabolic engineering strategy to assemble biosynthetic pathway for longifolene production in Esche
136 spectral database, enabled us to formulate a biosynthetic pathway for the biosynthesis of triptolide,
138 ibitor of TarO, an early stage enzyme in the biosynthetic pathway for wall teichoic acid (WTA) synthe
139 unds to cope with their environments but the biosynthetic pathways for most of these compounds have n
140 unds to cope with their environments but the biosynthetic pathways for most of these compounds have y
141 ics that are covered in this minireview are: biosynthetic pathways for N-acyl amino acids, receptors
143 Characterizing the structural components and biosynthetic pathways for these polysaccharides is key t
144 n catalyzed by four enzymes in the taromycin biosynthetic pathway from the marine bacterium Saccharom
145 ard 11 recombinant CPs of different types of biosynthetic pathways from cyanobacterial and Streptomyc
146 ing strategy aims at transferring polyketide biosynthetic pathways from their native producers into t
147 We show that copy numbers of triptolide biosynthetic pathway genes are impacted by a recent whol
148 e results suggest that manipulation of auxin biosynthetic pathway genes can be an effective approach
149 followed transcript levels of the cytokinin biosynthetic pathway genes in a sliding developmental zo
150 tes to transcriptional activity of clustered biosynthetic pathway genes in Arabidopsis thaliana Our a
151 patterns pinpoint alterations in hexosamine biosynthetic pathway, glycosylation and lipid metabolism
155 l importance of these polysaccharides, their biosynthetic pathways have received limited attention.
156 stead, glucose metabolized by the hexosamine biosynthetic pathway (HBP) allows nuclear localization o
157 , we identify the requirements of hexosamine biosynthetic pathway (HBP) and O-GlcNAc transferase (OGT
158 lar, an enhanced flux through the Hexosamine Biosynthetic Pathway (HBP) has been tightly linked to PC
160 , and other metabolites drive the hexosamine biosynthetic pathway (HBP) ultimately leading to the O-G
161 ate, leading to engagement of the hexosamine biosynthetic pathway (HBP), increased O-GlcNAcylation, a
162 branch pathway in glycolysis, the hexosamine biosynthetic pathway (HBP), to increase uridine diphosph
166 romiscuity of the anthraquinone heterologous biosynthetic pathway in E. coli to act as genetically ap
167 ulated and accelerated activation of the SCW biosynthetic pathway in fiber cells, as revealed by tran
170 he bacterial P450 MycCI from the mycinamicin biosynthetic pathway in Micromonospora griseorubida poss
172 Here we report the elucidation of the RA biosynthetic pathway in Phacelia campanularia (desert be
173 ed a third P450 homolog from the chalcomycin biosynthetic pathway in Streptomyces bikiniensis These s
176 Nocardia brasiliensis and reconstituted the biosynthetic pathway in vitro to link the gene cluster t
177 Using transgenic mice with altered CYP lipid biosynthetic pathways in a mouse model of laser-induced
178 y plastic, and that dynamic GNs generate new biosynthetic pathways in different Brassicaceae lineages
179 rtance of reactivation of AR-regulated lipid biosynthetic pathways in driving CRPC progression, and s
181 can be widely applied for rapid synthesis of biosynthetic pathways in general molecular biology labor
183 ctivity is required for the induction of SPM-biosynthetic pathways in human M2-like monocyte-derived
186 sight into the evolution of specific flavone biosynthetic pathways in the mint family, Lamiaceae, but
187 hree enzymes in the postsqualene cholesterol biosynthetic pathway including EBP, DHCR7, and DHCR24.
189 endocannabinoid, and although its canonical biosynthetic pathway involving phosphoinositide-specific
190 y transcriptome landscape of the beta-lactam biosynthetic pathway is analyzed, suggesting temporal ch
193 oupled and that flux through the cholesterol biosynthetic pathway is required for the maximal SREBP-1
194 P-PRT), as the first enzyme in the histidine biosynthetic pathway, is allosterically regulated by his
195 and a homologous enzyme from the kainic acid biosynthetic pathway, KabA, to reengineer their isoprene
196 entification of genes and elucidation of the biosynthetic pathway leading to triptolide are the prere
197 ted tissues, accompanied by induction of the biosynthetic pathways leading from Glc to anthocyanins.
198 e carbocation intermediates that connect the biosynthetic pathways leading to the sand fly pheromone
199 ion events are key regulators of the protein biosynthetic pathway, leading from rDNA transcription an
201 ally important commodities, yet beyond their biosynthetic pathways, little is known about the genetic
202 three areas: glycoengineering through glycan biosynthetic pathway manipulation, glycoengineering thro
203 sults highlight that the O(2)-independent UQ biosynthetic pathway may represent a target for antibiot
204 requirements and provide building blocks for biosynthetic pathways, metabolism is now appreciated for
206 rol forms in inoculated wild-type plants and biosynthetic pathway mutants, we provide biochemical ins
208 ere, we report that the last reaction in the biosynthetic pathway of APDs, catalyzed by F(420)H(2)-de
209 AH7PS), catalyzing the first reaction of the biosynthetic pathway of aromatic amino acids, and a chor
210 fully recode, construct and characterize the biosynthetic pathway of bikaverin, a tetracyclic polyket
214 ial avenues of study, including learning the biosynthetic pathway of cypridinid luciferin and genomic
217 uction of tropine, a key intermediate in the biosynthetic pathway of medicinal TAs such as scopolamin
218 dvanced analytical techniques to dissect the biosynthetic pathway of mono- and dimethyl FuFAs and the
219 y into a rich family of natural products.The biosynthetic pathway of preakuammicine, a monoterpene pr
221 s indole-3-acetaldoxime, suggesting that the biosynthetic pathway of this compound is channeled by th
222 mologous to the last step in the acylsucrose biosynthetic pathway of tomato (Solanum lycopersicum).
223 omic groups is important for determining the biosynthetic pathways of bioluminescent substrates, whic
225 ons are increasingly being recognized in the biosynthetic pathways of many structurally complex natur
227 their medical and biological importance, the biosynthetic pathways of prenylated stilbenoids remain t
228 death and identified early insufficiency in biosynthetic pathways of prohomeostatic/neuroprotective
229 urther knowledge of the ecological roles and biosynthetic pathways of secondary metabolites may shed
232 lysosomal degradation are either recycled in biosynthetic pathways or are further metabolized to prod
233 induced by perturbation of endogenous lipid biosynthetic pathways or exogenous application of lipid.
235 early Fe-S-dependent checkpoint in the heme biosynthetic pathway, our findings help explain why heme
236 y metabolites are synthesized through unique biosynthetic pathways, plants must orchestrate their pro
237 c analysis shows that the jasmonic acid (JA) biosynthetic pathway plays an important role in salt tol
238 ikely through its regulation of the cysteine biosynthetic pathway, plays a key role in the virulence
240 at recognize intermediates of the vitamin B2 biosynthetic pathway presented by the monomorphic MR1 mo
241 risk of patient death, highlighting that the biosynthetic pathway producing OCDO is of major importan
242 erge from the architecture of the underlying biosynthetic pathways, rather than requiring the evoluti
249 erization of TnmH from the tiancimycin (TNM) biosynthetic pathway, revealing that (i) TnmH catalyzes
250 p research have spontaneous mutations in the biosynthetic pathway(s) regulating the rhythmic producti
255 identified several genes in the sphingolipid biosynthetic pathway that are required for Gb3 synthesis
256 builds its cell wall peptidoglycan through a biosynthetic pathway that is dependent on transported ho
257 and sufficient for the induction of a lipid biosynthetic pathway that is expressed in plant cells ac
258 ed to diversify a heterologous beta-carotene biosynthetic pathway that produced genetic variants with
259 provide a platform to identify nonessential biosynthetic pathways that can be deleted in the E. coli
261 final two reactions in the mithramycin (MTM) biosynthetic pathway, the Baeyer-Villiger opening of the
263 isoprenoid intermediates in the cholesterol biosynthetic pathway, the post-translational prenylation
264 lls revealed that genes from the L-histidine biosynthetic pathway, the purine, pyrimidine de novo syn
266 sity-generating step in fungal meroterpenoid biosynthetic pathways: the multibond-forming polyene cyc
267 3 regulon and indole-3-carbonylnitrile (ICN) biosynthetic pathway through exaptation of a retroduplic
268 for terpenoids and installation of terpenoid biosynthetic pathways through direction of the enzymes t
269 xidase 7, a class III GA 2-oxidase in the GA biosynthetic pathway, through a bulked segregant analysi
271 reconstitution to elucidate a near-complete biosynthetic pathway to colchicine without prior knowled
272 ing protein 2a (PBP2a), is brought into this biosynthetic pathway to complete the cross-linking.
273 functions within the cytosolic glycerolipid biosynthetic pathway to esterify C16:0 to the middle pos
274 rferons (IFNs) can reprogram the cholesterol biosynthetic pathway to facilitate innate immune respons
275 d characterization of the concise two-enzyme biosynthetic pathway to kainic acid from l-glutamic acid
276 te to afford hydroxymethylphosphonate on the biosynthetic pathway to the commercial herbicide phosphi
277 gulates the activities of key enzymes within biosynthetic pathways to meet metabolic demand for their
279 noparticles (FNP) on emerging (non-aflatoxin biosynthetic pathway) toxins production in mycelia and y
280 coding functions to metabolism through their biosynthetic pathways, tRNA modifications are emerging a
282 major changes at each of these levels in the biosynthetic pathways used by local populations in their
283 amily-specific, trichome-localized acylsugar biosynthetic pathway using a combination of mass spectro
284 full elucidation of the Rhodiola salidroside biosynthetic pathway utilizing the first comprehensive t
285 but instead by disruption of the ergosterol biosynthetic pathway via inhibition of the 14alpha-demet
286 n inner membrane-associated, multicomponent, biosynthetic pathway via successive steps of isoprenyl t
287 roughput engineering of genetic circuits and biosynthetic pathways via directed mutagenesis of bacter
288 f genes encoding enzymes of the isoflavonoid biosynthetic pathway was also maximal in these cultivars
290 the consecutive ten steps of the monolignol biosynthetic pathway were identified in the S. viridis g
291 his study, the genetic components of patulin biosynthetic pathway were systematically dissected in Pe
294 Light harvesting and secondary metabolite biosynthetic pathways were numerous across lineages, hig
295 osanoids derived from AA via the CYP and LOX biosynthetic pathways were positively associated with SG
296 e Ziziphoid clade developed the triterpenoid biosynthetic pathway, whereas the Rhamnoid clade predomi
297 cosylation are synthesized in the hexosamine biosynthetic pathway, which is controlled by the glutami
298 novel possibilities for manipulating NAD(+) biosynthetic pathways, which is key for the future of th
299 ion that has resulted in the loss of certain biosynthetic pathways, which may offer clues for improvi