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1 employed to replace isomerases in vitro for biotransformation.
2 (UGT), and sulfotransferase (SULT)) in their biotransformation.
3 etoxification of co-occurring substances via biotransformation.
4 ic removal processes, primarily sorption and biotransformation.
5 izosphere soil, supporting the potential for biotransformation.
6 s of the AD process are also involved in OMP biotransformation.
7 alpha-methyl-L-tyrosine did not inhibit the biotransformation.
8 II to produce stable catalysts for efficient biotransformation.
9 omatography revealed no evidence of Mn-PyC3A biotransformation.
10 s the consequences for siRNA disposition and biotransformation.
11 stem-specific and mix up phase transfer with biotransformation.
12 ic processes such as uptake, elimination and biotransformation.
13 or enhanced functions such as micropollutant biotransformation.
14 SRTs promote higher rates of micropollutant biotransformation.
15 grase and a dioxygenase were involved in BAC biotransformation.
16 ng the roles played by AOA in micropollutant biotransformation.
17 are considerably lower than expected due to biotransformation.
18 CFs are sensitive to even very slow rates of biotransformation.
19 sorption sites and excellent conditions for biotransformation.
20 tudy reveals an unexpected 2-step process of biotransformation.
21 avones by bacteria plays a key role in their biotransformation.
22 ts has been extensively used to evaluate ADC biotransformation.
23 v) species differences; and (v) extrahepatic biotransformation.
24 t FABP1-KO mice exhibit reduced rates of THC biotransformation.
25 ow DO impacts the kinetics of micropollutant biotransformation.
26 inement, we believe, multiple micro-organism biotransformations.
27 etically modified microorganisms for complex biotransformations.
28 ntify taxonomic groups associated with those biotransformations.
30 vaccination, triiodothyronine (T3), hepatic biotransformation (7-ethoxyresorufin-O-deethylase activi
31 y approach to quantify industrially relevant biotransformations accurately, focusing on nitrile metab
36 s that focus on the mechanisms of pyrethroid biotransformation and endocrine toxicity to fishes acros
37 andards, and then applied to follow nicotine biotransformation and lipid assimilation in vivo to demo
38 s are sufficient to drive HLC and HepG2 drug biotransformation and liver-toxin sensitivity to levels
39 elated to the monoterpene-limonene secondary biotransformation and menthofuran has been identified as
40 l substrates were produced by P450-catalyzed biotransformation and microbial/plant enzyme systems wer
42 identify associations between micropollutant biotransformation and specific gene products in complex
51 concentrations, our current understanding of biotransformation at the level of enzyme-chemical intera
52 s a system-independent descriptor of aerobic biotransformation at the water-sediment interface that i
53 f prochloraz is not only caused by inhibited biotransformation but even more by increased azoxystrobi
54 ates were proatherogenic and whether arsenic biotransformation by As3MT was required for arsenic-enha
55 nal groups, we systematically explored amine biotransformation by conducting experiments with 19 comp
63 cal approach, we aimed to assess the hepatic biotransformation capacities of Antarctic fish species b
66 l changes becoming a more relevant factor in biotransformations catalyzed by more specific enzymes (e
67 ical-specific intracellular accumulation and biotransformation combined with paracellular and active
69 in the silane substrates untouched, and this biotransformation does not lead to disiloxane formation,
70 and model the impact of DO on pharmaceutical biotransformations during wastewater treatment and ident
71 y drug conjugates (ADCs) can undergo in vivo biotransformation (e.g., payload metabolism, deconjugati
72 idental release through chain shortening and biotransformation, emphasizing the importance of compoun
75 om half-lives determined in highly efficient biotransformation experiments in activated sludge to soi
77 etermined in highly time- and work-efficient biotransformation experiments with activated sludge and
78 study was to investigate the in vitro human biotransformation for three widely used BTRs and to step
81 ain covalently bound to the Ru ion showing a biotransformation from Ru(III)N2Cl4 to Ru(III)Clx(N/O)6-
85 t community functions such as micropollutant biotransformation in complex microbial communities, we p
88 recently reported, and the potential for CFC biotransformation in surface and groundwaters remains un
90 chemical C-H oxidation reactions complement biotransformation in the synthesis of drug metabolites?
93 e report a label-free screening platform for biotransformations in live colonies using desorption ele
95 ore detailed and accurate information on ADC biotransformations in vivo, enabling analysis of low-dos
96 conditions affecting the efficiency (96%) of biotransformation including substrate concentration, inc
97 ately 100 kDa) fragments contain the key ADC biotransformation information, such as drug-to-antibody
103 d to the liver, we non-invasively imaged the biotransformation kinetics in vivo at high specificity a
104 suggest that sewer biofilms can enhance the biotransformation kinetics of most selected compounds.
107 chemical reactions and genes involved in the biotransformation mechanism of AuCl4 into gold nanoparti
108 ctral databases with prediction of mammalian biotransformation metabolites, wrapper functions for in
109 oglutarate-dependent dioxygenase enzyme in a biotransformation methodology to efficiently construct k
110 edge gap, we investigated the atropselective biotransformation of 2,2',3,4',6-pentachlorobiphenyl (PC
111 s (SR) and class richness (CR) determine the biotransformation of a mixture of 37 structurally divers
113 applied to evaluate the in vitro and in vivo biotransformation of ADCs conjugated at different sites
115 c and functional diversity are important for biotransformation of anthropogenic chemicals in phytopla
116 S assay that can be utilized to evaluate the biotransformation of any site-specific ADC independent o
118 .5-129 mug/L), our findings reveal extensive biotransformation of atmospheric As and the enrichment o
119 tly, an array of eight genes involved in the biotransformation of benzalkonium chlorides (BACs)-an ac
122 9 define simulation tests aimed at assessing biotransformation of chemicals in water-sediment systems
124 by which the gut microbiome facilitates the biotransformation of drugs and impacts pharmacological e
125 s have already been implicated in the direct biotransformation of drugs, both from targeted case stud
127 chored cytochrome P450 enzyme engaged in the biotransformation of endo- and xenobiotics, including >5
128 aquatic species, this study investigated the biotransformation of fluoxetine in the zebrafish embryo
129 tween consumer microbiota configurations and biotransformation of food ingredients, should have a num
132 beta-Glucuronidase is the key enzyme in the biotransformation of GL to GAMG, but its activities need
135 role in the arsenic biogeochemical cycle by biotransformation of inorganic arsenic into organic arse
138 uptake and export are important steps in the biotransformation of mercury (Hg) by microorganisms.
139 date the ability of M. sedula to perform the biotransformation of meteorite minerals, unravel microbi
141 al species have biological imprints, how the biotransformation of minerals may have benefited microbi
143 ns only in the presence of TTC, suggesting a biotransformation of nitrogenous compounds in Bacillus s
144 zed proresolving mediators and show that the biotransformation of NPD1 by human hepatoma cells is ext
145 (CSIA) is a promising approach for tracking biotransformation of organic pollutants, but isotope fra
148 ctyl sulfonate (PFOS) through inhalation and biotransformation of PFAS precursors in air were estimat
153 filtered water quality primarily through the biotransformation of pollutants and nutrients rather tha
157 monene-1,2-diol with the already established biotransformation of R-(+)-limonene into alpha-terpineol
158 al knowledge about the interactions with and biotransformation of REE present in a natural mineral re
164 Consistent with its role as a THC carrier, biotransformation of THC was reduced in primary hepatocy
165 by readily available l-histidine followed by biotransformation of the aldol adduct by an alcohol dehy
168 ransformation strongly affected the rates of biotransformation of the hydroxyl groups, which in some
169 oduce foods that support efficient microbial biotransformation of their ingredients into metabolic pr
171 a major community function, but also for the biotransformation of two nitrile-containing micropolluta
172 scription factor governing the transport and biotransformation of various drugs and other chemicals.
173 the potential to increase access to, and the biotransformation of, contaminant mass within the subsur
175 sociated with antibody drug conjugates, such biotransformations of tethered antibody formats usually
176 nfluence of physical-chemical properties and biotransformation on bioaccumulation behavior of these c
177 c as a model compound to study the impact of biotransformation on the bioaccumulation potential and t
179 expressions of a battery of genes related to biotransformation, oxidative stress, and endocrine disru
181 size that it is important to investigate the biotransformation pathway to assess overall exposure to
184 inhibition; fermentative, nonexoelectrogenic biotransformation pathways of the five compounds were no
185 SIA) to track the aerobic biodegradation and biotransformation pathways of the most prominent isomers
188 xperimental evidence (such as information on biotransformation pathways) increases the likelihood of
191 ure is a key factor that influences chemical biotransformation potential and rates, on which exposure
192 Es from the human body, e.g., differences in biotransformation potential of congeners, growth dilutio
195 form R package for in silico drug phase I/II biotransformation prediction and mass-spectrometric data
196 This work aimed to develop a whole-cell biotransformation process for the production of alpha-ke
198 approach was used to elucidate the microbial biotransformation processes of polyphenols following dig
199 -bound As, or the indirect stimulation of As biotransformation processes, which are presently not con
200 enormous potential in bioremediation and for biotransformations producing bulk and fine chemicals, an
201 ADME evaluation, contextualizing the site of biotransformation product formation with PK-PD modulatio
204 xiconazole, prochloraz, and their respective biotransformation products (BTPs) were studied to gain i
209 Our findings provide new identified in vitro biotransformation products for future biomonitoring stud
212 evaluated to maximize incorporation of DNAN biotransformation products into the nonextractable soil
214 on rates of parent antiviral drugs and their biotransformation products were similar, indicating that
215 Catechol and phenol, which were persistent biotransformation products, inhibited exoelectrogenesis
216 nts, drugs, and antibiotics as well as their biotransformation products, through its expansion with o
217 at a high concentration, as opposed to their biotransformation products, were responsible for the obs
218 h different combinations of partitioning and biotransformation properties at various rates of lipid l
219 ke viridicatumtoxins are resistant to fungal biotransformation, providing chemical insights that coul
220 es could be explained by their effect on the biotransformation rate but that this effect could only p
221 ilm (500 mum) presented the highest specific biotransformation rate constants (kbio, L g(-1) d(-1)) f
223 ions, we demonstrated that the estimation of biotransformation rate constants in biofilm can be signi
224 n to experimental results allowed estimating biotransformation rate constants in sewer biofilms, whic
227 ulation assessment and to develop an in vivo biotransformation rate database for QSAR development and
229 ransformed within 7-day batch runs and their biotransformation rate increased with increasing initial
230 anism of synergy is the azole decreasing the biotransformation rate of alpha-cypermethrin and validat
231 ical to diminish lag times and increased the biotransformation rate of NTO in nearly all cases indica
233 of the mixture of the five compounds, their biotransformation rate ranged from 0.85 to 2.34 mM/d.
234 hepatic in vitro rates scaled to whole body biotransformation rates (k(B)) were compared against in
235 s, the model incorporating measured in vitro biotransformation rates and assuming no correction for p
237 line HepaRG shared many similarities, while biotransformation rates in cell lines widely used for es
240 n environmental exposure assessment to adapt biotransformation rates to actual temperatures, assuming
241 impact of DO concentration on pharmaceutical biotransformation rates via two approaches: (1) Determin
244 ointestinal biotransformation rates, somatic biotransformation rates, bioconcentration factors (BCF),
245 ucted to derive the in vivo gastrointestinal biotransformation rates, somatic biotransformation rates
250 showed that the inhibition of CYP-catalyzed biotransformation reactions indeed played a role for the
251 es in kinetics of different antiviral drugs, biotransformation reactions mainly involved oxidation of
252 the cases of nitrile hydration and oxidative biotransformation reactions to show that the considerati
256 xcept for prochloraz, which showed extensive biotransformation reactions with 18 BTPs detected that w
257 s appeared to undergo mostly similar initial biotransformation reactions, with substitution-type reac
262 nd most metabolites was clearly reduced, and biotransformation shifted in favor of norfluoxetine, the
264 and refine pathway prediction, comprehensive biotransformation studies for compounds exhibiting perti
266 ugates, or bispecific antibodies may undergo biotransformation (such as clipping, deamidation, or oxi
267 unts for 10-90% of the measured methanogenic biotransformation, suggesting that other active enzymes
270 results suggest that ArsH catalyzes a novel biotransformation that confers resistance to environment
272 cteria are capable of performing a number of biotransformations that may activate or deactivate xenob
275 -acrylic compounds and apply this whole-cell biotransformation to the synthesis of aminolevulinic aci
276 hotrophy, based on inorganic iron and sulfur biotransformations, to autotrophy, to chemoheterotrophy
277 nocatalytic aldol reaction with a subsequent biotransformation toward a "one-pot-like" process for th
278 on of sclerotiorin color was accomplished by biotransformation using Beauveria bassiana generating a
279 the catalytic performance was evaluated for biotransformation using whole cells exemplified for the
281 e gene ber) was sufficient for the first two biotransformations, variable between strains of Eggerthe
282 dministering protein therapeutics, including biotransformation via clipping, deamidation, isomerizati
283 factors, relative to Aroclor 1254, suggested biotransformation (via cytochrome P450) and bioaccumulat
285 that the citrus peel extract obtained after biotransformation was a good source of hesperitin and na
287 knockout mice to test whether As3MT-mediated biotransformation was required for the proatherogenic ef
292 ar, the major bioproducts from each of these biotransformations were found at different oxidation lev
293 dance of labeled taxa suggest that BP and BZ biotransformations were performed by microorganisms with
294 rements of in vivo activity using whole-cell biotransformations, where two Escherichia coli strains e
295 lutants during activated sludge treatment is biotransformation, which often leads to the formation of
296 ver, the mechanisms and factors behind these biotransformations, which are essential for elucidating
298 ze Pickering emulsions and catalyze biphasic biotransformation with superior enzymatic stability and
299 near complete mass recovery of FtTAoS after biotransformation, with 10% (mol/mol) of the amended FtT